CN101904938A - Kidney-tonifying heath traditional Chinese medicine composition and preparation method thereof - Google Patents

Kidney-tonifying heath traditional Chinese medicine composition and preparation method thereof Download PDF

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CN101904938A
CN101904938A CN2010102284620A CN201010228462A CN101904938A CN 101904938 A CN101904938 A CN 101904938A CN 2010102284620 A CN2010102284620 A CN 2010102284620A CN 201010228462 A CN201010228462 A CN 201010228462A CN 101904938 A CN101904938 A CN 101904938A
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kidney
radix
chinese medicine
radix rehmanniae
ethanol
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杨建雲
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Abstract

The invention provides kidney-tonifying heath traditional Chinese medicine composition and preparation method thereof. The composition is prepared from the following raw materials: 1-4 parts of male silkworm moth, 1-4 parts of acanthopanax, 1-3 parts of dodder, 1-3 parts of epimedium, 0.1-2 parts of rehmanniae, and 0.1-2 parts of psoralea. The composition has the advantages of reasonable prescription, concise proportioning, accurate therapy effect, good clinical effect, and functions of tonifying kidney and strengthening yang, replenishing essence and nourishing marrow, and the like, is used for treating impotence, premature ejaculation, weakness of the penis in erection, sexuality decrease, prostatoplasia , prostatitis, sterility caused by no sperm, little sperm or decrease of sperm activity, is suitable for people with low immunity, and also can be used for the regular health care and the like of middle and old men.

Description

A kind of kidney-tonifying heath Chinese medicine composition and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine composition and preparation method thereof, especially a kind of kidney supplementing yang invigorating health care Chinese medicine composition and preparation method thereof belongs to field of medicaments.
Background technology
At present, deficiency of kidney essence, impotence and premature ejaculation, emission, soreness of waist and knee joint, frequent micturition, lift and not hard, libido descends, prostatic hyperplasia, prostatitis, the symptoms such as sterility and infertility that azoospermia, few essence or motility of sperm descend and cause are usually perplexing middle-aging male, existing medicament exists side effect big, problems such as unsatisfactory curative effect in this symptom of treatment, prepare a kind of side effect little, improve patient's immunity, the health care medicine that can be used for the middle-aging male routine again is a problem demanding prompt solution.
Summary of the invention
Big for overcoming existing medicament side effect, problems such as unsatisfactory curative effect the object of the present invention is to provide that a kind of side effect is little, use amount is few, absorb kidney-tonifying heath Chinese medicine completely, adopt following a few flavor medical materials, and pharmacology analysis is as follows:
Male Bombycis mori, salty in the mouth, temperature heat.It is the medicine-food two-purpose medical material that the strong essence of male used always is healthy and strong.Have the liver and the kidney tonifying, nocturnal control and yang nourishing, anti-senility, main beneficial vital essence, the reinforcing YIN-essence road, warming the kidney, the smart hematuria of stopping leak is controlled the function of seminal emission reddish and whitish turbid urine, is monarch drug.Treatment sexual impotence, nebulousurine (prostatitis), hematuria, prostate hyperplasia, functional anemia, geromorphism etc. all there is sure curative effect.Sun Simiao " preemergency a thousand pieces of gold prescription ", Song dynasty well-known doctor Zhao closely question at " Shengji Zonglu ", Yuan Dynasty well-known doctor Zhu Zhenheng all on the booksly at " danxi's experiential therapy " and Ming Dynasty well-known doctor Li Shizhen (1518-1593 A.D.) Compendium of Material Medica, all given the therapeutic evaluation of height.Modern study is found to contain brain hormone, ecdyson, juvenile hormone in the male Bombycis mori, is not have in other biological medicine and irreplaceable tonification hormone.Brain hormone: be excretory hormone in the male Bombycis mori cranial nerve cell, can regulate the fertility activity, obviously delay and resist human senility, postpone involutional arrival.Ecdyson: be the active substance in the male moth body, human body is had the growth of the cell of promotion, stimulate the hypodermal cell division, produce the new life cells and the effect of sexual cell, and have obvious promotion insulin cell to upgrade regenerated ability.Juvenile hormone: have the control specific proteins synthetic, promote growth, stop aged function.In addition, male Bombycis mori also is rich in the aminoacid of needed by human body, and known Bombycis mori contains aminoacid kind more than 20, to tissue growth with upgrade, safeguard that the nervous system normal function all can have better action.For being used for defying age, the traditional Chinese medical science provides material base.
Herba Epimedii has another name called Herba Epimedii.Acrid in the mouth, sweet, warm in nature.Return liver, kidney channel.The function kidney invigorating and YANG supporting.It is sterile to cure mainly sexual impotence, and modern study confirms that this product contains chemical constituents such as icariine, has androgen-like action.Fructus Psoraleae claims Fructus Psoraleae again.Bitter in the mouth, suffering, the big temperature of property.Return kidney, spleen channel.The function kidney invigorating and YANG supporting, the controlling nocturnal emission with astringent drugs reducing urination.Modern study contains compositions such as coumarin, Bakuchiol.Cure mainly impotence due to deficiency of the kidney, seminal emission, the enuresis, frequent micturition.
Fructus Psoraleae comes from Lei Gong's Treatise on Preparation and Broiling of Materia Medica, cures mainly that reinforcing the kidney and supporting YANG, helping inspiration to relieve asthma, warming spleen and stopping diarrha, insufficiency of kidney-YANG, below element deficiency and cold, chills and pain of the waist and kness, sexual impotence essence, frequent micturition, the enuresis, failure of the kidney in receiving QI, dyspnea due to deficiency are more than, asthenia of both the spleen and kidney etc.With Herba Epimedii be ministerial drug altogether
The Semen Cuscutae suffering, sweet, flat.Return liver, kidney, spleen channel.The YANG invigorating tonifying YIN, the controlling nocturnal emission with astringent drugs reducing urination: cure mainly and suffer from a deficiency of the kidney admittedly, disease is seen seminal emission, spermatorrhea, sexual impotence, the urine nebulousurine, the heeltap reaches cards such as waist soreness not to the utmost, and modern study contains Quercetin, glycoside, and the treatment prostatic hyperplasia is suitable with finasteride.
Radix Et Caulis Acanthopanacis Senticosi sees Shennong's Herbal, classifies as top grade.Acrid in the mouth, little hardship, warm in nature, nontoxic.Good replenishing QI to invigorate the spleen, the effect of tonifying the kidney for tranquilization are arranged.Cure mainly diseases such as soreness of the waist and knees, body void are weak, insomnia.Radix Et Caulis Acanthopanacis Senticosi still contains superoxide dismutase (SOD) complex, has the antioxidative function, can improve the generation of body immunity and opposing free radical.
Radix Rehmanniae, sweet, tepor.Return liver, kidney channel.Nourishing YIN and supplementing blood, beneficial essence is filled out marrow.Be used for the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, early whitening of beard and hair etc.Semen Cuscutae, Radix Et Caulis Acanthopanacis Senticosi and Radix Rehmanniae Preparata make it medicine for assistant altogether.
Kidney-tonifying heath Chinese medicine composition provided by the invention is characterized in that being made up of following component:
1~4 part of male Bombycis mori, 1~4 part of Radix Et Caulis Acanthopanacis Senticosi,
1~3 part of Semen Cuscutae, 1~3 part of Herba Epimedii,
0.1~2 part of Radix Rehmanniae, 0.1~2 part of Fructus Psoraleae.
Another object of the present invention is to provide the preparation method of this Chinese medicine composition, it is characterized in that by following each step:
A, get the raw materials ready by following mass component:
1~4 part of male Bombycis mori, 1~4 part of Radix Et Caulis Acanthopanacis Senticosi,
1~3 part of Semen Cuscutae, 1~3 part of Herba Epimedii,
0.1~2 part of Radix Rehmanniae, 0.1~2 part of Fructus Psoraleae;
B, with mass ratio 2~20: 1, male Bombycis mori is added in the edible wine of 36~95% concentration, fully behind the mixing, soaked under the room temperature 10~60 days, collect soak, discard medicinal residues;
C, get Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, Radix Rehmanniae and Fructus Psoraleae, press mass ratio 1: 2~15, add the ethanol of 50~95% concentration, extracting 2~10h collects extracting solution and medicinal residues;
D, get the medicinal residues of gained among the C, press mass ratio 1: 2~10, add the ethanol of 50~95% concentration, extracting 1~6h collects extracting solution, discards medicinal residues;
E, the extracting solution of C and D gained is merged;
F, the supernatant of E gained is concentrated, and recovery ethanol, the ethanol content of adjusting liquid after concentrating leaves standstill 12~48h after-filtration 50~95%, gets filtrate and precipitate, with precipitate with 50~95% washing with alcohol, get cleaning mixture and last precipitate, discard last precipitate, filtrate and cleaning mixture are merged, reclaim ethanol to there not being the alcohol flavor, promptly get the total extract of Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, Radix Rehmanniae and Fructus Psoraleae;
G, get among the B that the total extract of gained merges mixing in the gained soak and F, promptly get the kidney-tonifying heath Chinese medicine composition.
Chinese medicine composition preparation method of the present invention, also can be by following each step:
A, get the raw materials ready by following mass component:
1~4 part of male Bombycis mori, 1~4 part of Radix Et Caulis Acanthopanacis Senticosi,
1~3 part of Semen Cuscutae, 1~3 part of Herba Epimedii,
0.1~2 part of Radix Rehmanniae, 0.1~2 part of Fructus Psoraleae;
B, with mass ratio 2~20: 1, male Bombycis mori is added in the edible wine of 36~95% concentration, stirred under the room temperature 1~10 day, collect soak, discard medicinal residues;
C, get Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, Radix Rehmanniae and Fructus Psoraleae, be ground into Powderedly, press mass ratio 1: 6~15, add the ethanol of 50~95% concentration, extracting 4~8h collects extracting solution, discards medicinal residues;
D, get the extracting solution of gained among the C, reclaim ethanol, the ethanol content of adjusting liquid after concentrating leaves standstill 12~48h after-filtration 50~95%, gets filtrate and precipitate, and with precipitate with 50~95% washing with alcohol, get cleaning mixture and last precipitate, discard last precipitate, filtrate and cleaning mixture are merged, reclaim ethanol to there not being the alcohol flavor, promptly get the total extract of Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, Radix Rehmanniae and Fructus Psoraleae;
E, get among the B that the total extract of gained merges mixing in the gained soak and D, promptly get the kidney-tonifying heath Chinese medicine composition.
Described edible wine is grain wine or ethanol.
Described Semen Cuscutae is a processed with wine.
Described Radix Rehmanniae is Radix Rehmanniae Preparata or Radix Rehmanniae.
Described Radix Rehmanniae Preparata is a processed with salt.
Described Fructus Psoraleae is a processed with salt.
After making the kidney-tonifying heath Chinese medicine composition, utilize methods such as Enzymatic Extraction in the prior art, ultrasonic method extraction, extraction extraction compositions to be extracted refining again, make preparation again, as preparation series such as oral liquid, medicated wine, extractum, hard capsule, soft capsule, tablet, drop pill, granules, both guaranteed the effectiveness of this compositions, control the safety and the use amount of this compositions again, be convenient for carrying use.
Advantage of the present invention and effect: this medicine reasonable recipe, prescription is simplified, determined curative effect, clinical effectiveness is fine, be widely used in relevant section office of internal medicine and the conventional health care of middle-aging male, the combination of male Bombycis mori, Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, Radix Rehmanniae Preparata and Fructus Psoraleae or plus-minus application on our basis all can reach the effect of perfect pair.Chinese medicine composition provided by the invention has kidney invigorating and YANG supporting, functions such as life essence-filling, marrow-benefitting, be used for sexual impotence, premature ejaculation is lifted and not hard, libido descends, prostatic hyperplasia, prostatitis, the sterility and infertility that azoospermia, few essence or motility of sperm descend and cause, the immunocompromised person promptly can be used for the health care of middle-aging male routine etc.
The specific embodiment
Below in conjunction with embodiment the present invention is described further.
Embodiment 1
A, get the raw materials ready by following mass component:
Male Bombycis mori 40 grams, Radix Et Caulis Acanthopanacis Senticosi 10 grams,
Semen Cuscutae 19 grams, Herba Epimedii 10 grams,
Radix Rehmanniae 1 gram Fructus Psoraleae 20 grams;
B, male Bombycis mori is added 240 gram concentration is in 36% the jowar wine, fully behind the mixing, soaks 60 days under the room temperature, collects soak, discards medicinal residues;
C, get Radix Et Caulis Acanthopanacis Senticosi, processed with wine Semen Cuscutae, Herba Epimedii, Radix Rehmanniae Preparata and Fructus Psoraleae, add 360 gram concentration and be 95% ethanol, reflux extracting 2h collects extracting solution and medicinal residues;
D, get the medicinal residues of gained among the C, pressed mass ratio 1: 4, add the ethanol of 95% concentration, reflux extracting 2h collects extracting solution, discards medicinal residues;
E, the extracting solution of C and D gained is merged;
F, the supernatant of E gained is concentrated, and recovery ethanol, the ethanol content of adjusting liquid after concentrating leaves standstill the 48h after-filtration 70%, gets filtrate and precipitate, with precipitate with 50% washing with alcohol, get cleaning mixture and last precipitate, discard last precipitate, filtrate and cleaning mixture are merged, reclaim ethanol to there not being the alcohol flavor, promptly get the total extract of Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, Radix Rehmanniae and Fructus Psoraleae;
G, get among the B that the total extract of gained merges mixing in the gained soak and F, promptly get the kidney-tonifying heath Chinese medicine composition.
Embodiment 2
A, get the raw materials ready by following mass component:
Male Bombycis mori 25 grams, Radix Et Caulis Acanthopanacis Senticosi 25 grams,
Semen Cuscutae 10 grams, Herba Epimedii 20 grams,
Radix Rehmanniae 10 gram Fructus Psoraleaes 10 grams;
B, male Bombycis mori is added 50 gram concentration is in 52% the big rice wine, fully behind the mixing, soaks 30 days under the room temperature, collects soak, discards medicinal residues;
C, get Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, Radix Rehmanniae and processed with salt Fructus Psoraleae, add 1125 gram concentration and be 70% ethanol, reflux extracting 4h collects extracting solution and medicinal residues;
D, get the medicinal residues of gained among the C, pressed mass ratio 1: 10, add the ethanol of 70% concentration, reflux extracting 1h collects extracting solution, discards medicinal residues;
E, the extracting solution of C and D gained is merged;
F, the supernatant of E gained is concentrated, and recovery ethanol, the ethanol content of adjusting liquid after concentrating leaves standstill the 24h after-filtration 95%, gets filtrate and precipitate, with precipitate with 70% washing with alcohol, get cleaning mixture and last precipitate, discard last precipitate, filtrate and cleaning mixture are merged, reclaim ethanol to there not being the alcohol flavor, promptly get the total extract of Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, Radix Rehmanniae and Fructus Psoraleae;
G, get among the B that the total extract of gained merges mixing in the gained soak and F, promptly get the kidney-tonifying heath Chinese medicine composition.
Embodiment 3
A, get the raw materials ready by following mass component:
Male Bombycis mori 10 grams, Radix Et Caulis Acanthopanacis Senticosi 29 grams,
Semen Cuscutae 30 grams, Herba Epimedii 20 grams,
Radix Rehmanniae 10 gram Fructus Psoraleaes 1 gram;
B, male Bombycis mori is added 200 gram concentration is in 95% the little ale, fully behind the mixing, soaks 10 days under the room temperature, collects soak, discards medicinal residues;
C, get Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, processed with salt Radix Rehmanniae Preparata and Fructus Psoraleae, add 180 gram concentration and be 50% ethanol, reflux extracting 10h collects extracting solution and medicinal residues;
D, get the medicinal residues of gained among the C, pressed mass ratio 1: 2, add the ethanol of 50% concentration, reflux extracting 6h collects extracting solution, discards medicinal residues;
E, the extracting solution of C and D gained is merged;
F, the supernatant of E gained is concentrated, and recovery ethanol, the ethanol content of adjusting liquid after concentrating leaves standstill the 12h after-filtration 50%, gets filtrate and precipitate, with precipitate with 95% washing with alcohol, get cleaning mixture and last precipitate, discard last precipitate, filtrate and cleaning mixture are merged, reclaim ethanol to there not being the alcohol flavor, promptly get the total extract of Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, Radix Rehmanniae and Fructus Psoraleae;
G, get among the B that the total extract of gained merges mixing in the gained soak and F, promptly get the kidney-tonifying heath Chinese medicine composition.
Embodiment 4
A, get the raw materials ready by following mass component:
Male Bombycis mori 10 grams, Radix Et Caulis Acanthopanacis Senticosi 40 grams,
Semen Cuscutae 10 grams, Herba Epimedii 10 grams,
Radix Rehmanniae 20 gram Fructus Psoraleaes 10 grams;
B, male Bombycis mori is added 20 gram concentration is in 95% the ethanol, stirs 1 day under the room temperature, collects soak, discards medicinal residues;
C, get Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, processed with salt Radix Rehmanniae and processed with salt Fructus Psoraleae, be ground into Powderedly, add 1350 gram concentration and be 70% ethanol, extracting 6h collects extracting solution, discards medicinal residues;
D, get the extracting solution of gained among the C, reclaim ethanol, the ethanol content of adjusting liquid after concentrating leaves standstill the 48h after-filtration 95%, gets filtrate and precipitate, and with precipitate with 95% washing with alcohol, get cleaning mixture and last precipitate, discard last precipitate, filtrate and cleaning mixture are merged, reclaim ethanol to there not being the alcohol flavor, promptly get the total extract of Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, Radix Rehmanniae and Fructus Psoraleae;
E, get among the B that the total extract of gained merges mixing in the gained soak and D, promptly get the kidney-tonifying heath Chinese medicine composition.
Embodiment 5
A, get the raw materials ready by following mass component:
Male Bombycis mori 29 grams, Radix Et Caulis Acanthopanacis Senticosi 10 grams,
Semen Cuscutae 20 grams, Herba Epimedii 30 grams,
Radix Rehmanniae 1 gram Fructus Psoraleae 10 grams;
B, male Bombycis mori is added 290 gram concentration is in 52% the corn wine, stirs 10 days under the room temperature, collects soak, discards medicinal residues;
C, get Radix Et Caulis Acanthopanacis Senticosi, processed with wine Semen Cuscutae, Herba Epimedii, Radix Rehmanniae and processed with salt Fructus Psoraleae, be ground into Powderedly, add 700 gram concentration and be 95% ethanol, extracting 4h collects extracting solution, discards medicinal residues;
D, get the extracting solution of gained among the C, reclaim ethanol, the ethanol content of adjusting liquid after concentrating leaves standstill the 24h after-filtration 70%, gets filtrate and precipitate, and with precipitate with 50% washing with alcohol, get cleaning mixture and last precipitate, discard last precipitate, filtrate and cleaning mixture are merged, reclaim ethanol to there not being the alcohol flavor, promptly get the total extract of Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, Radix Rehmanniae and Fructus Psoraleae;
E, get among the B that the total extract of gained merges mixing in the gained soak and D, promptly get the kidney-tonifying heath Chinese medicine composition.
Embodiment 6
A, get the raw materials ready by following mass component:
Male Bombycis mori 40 grams, Radix Et Caulis Acanthopanacis Senticosi 10 grams,
Semen Cuscutae 19 grams, Herba Epimedii 10 grams,
Radix Rehmanniae 1 gram Fructus Psoraleae 20 grams;
B, male Bombycis mori is added 800 gram concentration is in 36% the ethanol, stirs 5 days under the room temperature, collects soak, discards medicinal residues;
C, get Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, processed with salt Radix Rehmanniae Preparata and processed with salt Fructus Psoraleae, be ground into Powderedly, add 360 gram concentration and be 50% ethanol, extracting 8h collects extracting solution, discards medicinal residues;
D, get the extracting solution of gained among the C, reclaim ethanol, the ethanol content of adjusting liquid after concentrating leaves standstill the 12h after-filtration 50%, gets filtrate and precipitate, and with precipitate with 70% washing with alcohol, get cleaning mixture and last precipitate, discard last precipitate, filtrate and cleaning mixture are merged, reclaim ethanol to there not being the alcohol flavor, promptly get the total extract of Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, Radix Rehmanniae and Fructus Psoraleae;
E, get among the B that the total extract of gained merges mixing in the gained soak and D, promptly get the kidney-tonifying heath Chinese medicine composition.
Adopt the Chinese medicine composition of the embodiment of the invention 1, human body carried out clinical efficacy testing:
The treatment of kidney deficiency: the age is 40~65 years old male, totally 300 examples, soreness of the waist and knees patient 214 examples wherein, refreshing tired weak patient's 280 examples, frequent micturition patient's 181 examples, impotence patient 117 examples, hyposexuality patient 254 examples, sombre patient's 173 examples.The tablet oral, that this compositions of 5g is made, 2 times on the one.Use a course of treatment continuously, be 30 days a course of treatment.
The clinical observation of treatment kidney deficiency
Figure BSA00000193181200101
The treatment of hyperplasia of prostate: the age is 45~68 years old male, frequent micturition patient's 60 examples, nocturia increased frequency patient 60 examples, urinate and delay interrupted patient's 48 examples, trouble urinating patient 44 examples, difficulty in micturition and sound of rain pattering patient 48 examples, the urine line carefully reaches short patient's 48 examples of range.The drop pill oral, that this compositions of 5g is made, 2 times on the one.Use a course of treatment continuously, be 30 days a course of treatment.
The clinical observation of treatment hyperplasia of prostate
Figure BSA00000193181200102
Conclusion: as can be seen, this product all has the improvement effect to the cardinal symptom of kidney deficiency, hyperplasia of prostate from the observation of symptoms table, and is especially comparatively desirable to frequent micturition, soreness of the waist and knees, refreshing tired weak, hyposexuality, nocturnal emission, doing well,improving such as sombre.Purified Chinese medicine composition extract has efficiently, the good product of safe without toxic side effect so extract by above preparation technology.

Claims (8)

1. kidney-tonifying heath Chinese medicine composition is characterized in that being made up of following component:
1~4 part of male Bombycis mori, 1~4 part of Radix Et Caulis Acanthopanacis Senticosi,
1~3 part of Semen Cuscutae, 1~3 part of Herba Epimedii,
0.1~2 part of Radix Rehmanniae, 0.1~2 part of Fructus Psoraleae.
2. the preparation method of a kidney-tonifying heath Chinese medicine composition is characterized in that by following each step: A, gets the raw materials ready by following mass component:
1~4 part of male Bombycis mori, 1~4 part of Radix Et Caulis Acanthopanacis Senticosi,
1~3 part of Semen Cuscutae, 1~3 part of Herba Epimedii,
0.1~2 part of Radix Rehmanniae, 0.1~2 part of Fructus Psoraleae;
B, with mass ratio 2~20: 1, male Bombycis mori is added in the edible wine of 36~95% concentration, fully behind the mixing, soaked under the room temperature 10~60 days, collect soak, discard medicinal residues;
C, get Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, Radix Rehmanniae and Fructus Psoraleae, press mass ratio 1: 2~15, add the ethanol of 50~95% concentration, extracting 2~10h collects extracting solution and medicinal residues;
D, get the medicinal residues of gained among the C, press mass ratio 1: 2~10, add the ethanol of 50~95% concentration, extracting 1~6h collects extracting solution, discards medicinal residues;
E, the extracting solution of C and D gained is merged;
F, the supernatant of E gained is concentrated, and recovery ethanol, the ethanol content of adjusting liquid after concentrating leaves standstill 12~48h after-filtration 50~95%, gets filtrate and precipitate, with precipitate with 50~95% washing with alcohol, get cleaning mixture and last precipitate, discard last precipitate, filtrate and cleaning mixture are merged, reclaim ethanol to there not being the alcohol flavor, promptly get the total extract of Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, Radix Rehmanniae and Fructus Psoraleae;
G, get among the B that the total extract of gained merges mixing in the gained soak and F, promptly get the kidney-tonifying heath Chinese medicine composition.
3. the preparation method of a kidney-tonifying heath Chinese medicine composition is characterized in that by following each step:
A, get the raw materials ready by following mass component:
1~4 part of male Bombycis mori, 1~4 part of Radix Et Caulis Acanthopanacis Senticosi,
1~3 part of Semen Cuscutae, 1~3 part of Herba Epimedii,
0.1~2 part of Radix Rehmanniae, 0.1~2 part of Fructus Psoraleae;
B, with mass ratio 2~20: 1, male Bombycis mori is added in the edible wine of 36~95% concentration, stirred under the room temperature 1~10 day, collect soak, discard medicinal residues;
C, get Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, Radix Rehmanniae and Fructus Psoraleae, be ground into Powderedly, press mass ratio 1: 6~15, add the ethanol of 50~95% concentration, extracting 4~8h collects extracting solution, discards medicinal residues;
D, get the extracting solution of gained among the C, reclaim ethanol, the ethanol content of adjusting liquid after concentrating leaves standstill 12~48h after-filtration 50~95%, gets filtrate and precipitate, and with precipitate with 50~95% washing with alcohol, get cleaning mixture and last precipitate, discard last precipitate, filtrate and cleaning mixture are merged, reclaim ethanol to there not being the alcohol flavor, promptly get the total extract of Radix Et Caulis Acanthopanacis Senticosi, Semen Cuscutae, Herba Epimedii, Radix Rehmanniae and Fructus Psoraleae;
E, get among the B that the total extract of gained merges mixing in the gained soak and D, promptly get the kidney-tonifying heath Chinese medicine composition.
4. according to the preparation method of claim 2 or 3 described kidney-tonifying heath Chinese medicine compositions, it is characterized in that: described edible wine is grain wine or ethanol.
5. according to claim 1,2 or 3 described kidney-tonifying heath Chinese medicine compositions and preparation method thereof, it is characterized in that: described Semen Cuscutae is a processed with wine.
6. according to claim 1,2 or 3 described kidney-tonifying heath Chinese medicine compositions and preparation method thereof, it is characterized in that: described Radix Rehmanniae is Radix Rehmanniae Preparata or Radix Rehmanniae.
7. according to claim 1,2 or 3 described kidney-tonifying heath Chinese medicine compositions and preparation method thereof, it is characterized in that: described Radix Rehmanniae Preparata is a processed with salt.
8. according to claim 1,2 or 3 described kidney-tonifying heath Chinese medicine compositions and preparation method thereof, it is characterized in that: described Fructus Psoraleae is a processed with salt.
CN2010102284620A 2010-07-16 2010-07-16 Kidney-tonifying heath traditional Chinese medicine composition and preparation method thereof Pending CN101904938A (en)

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Cited By (3)

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Publication number Priority date Publication date Assignee Title
CN102512639A (en) * 2011-12-31 2012-06-27 徐海洋 Traditional Chinese medicinal kidney-tonifying pill for treating male infertility
CN105193715A (en) * 2015-10-23 2015-12-30 云南云龙制药股份有限公司 Preparation method for Torvosaurus liquid and application of Torvosaurus liquid
CN108324815A (en) * 2018-05-14 2018-07-27 金华市华萃医药研究所有限公司 A kind of composition for sex dysfunctions such as prospermia of males

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102512639A (en) * 2011-12-31 2012-06-27 徐海洋 Traditional Chinese medicinal kidney-tonifying pill for treating male infertility
CN105193715A (en) * 2015-10-23 2015-12-30 云南云龙制药股份有限公司 Preparation method for Torvosaurus liquid and application of Torvosaurus liquid
CN105193715B (en) * 2015-10-23 2017-12-12 云南云龙制药股份有限公司 A kind of preparation method and application of Torvosaurus liquid
CN108324815A (en) * 2018-05-14 2018-07-27 金华市华萃医药研究所有限公司 A kind of composition for sex dysfunctions such as prospermia of males

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