CN103908628B - A kind of herbal enema medicament treating chronic pelvic inflammatory disease and preparation method thereof - Google Patents

A kind of herbal enema medicament treating chronic pelvic inflammatory disease and preparation method thereof Download PDF

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CN103908628B
CN103908628B CN201410095029.2A CN201410095029A CN103908628B CN 103908628 B CN103908628 B CN 103908628B CN 201410095029 A CN201410095029 A CN 201410095029A CN 103908628 B CN103908628 B CN 103908628B
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radix
inflammatory disease
pelvic inflammatory
chronic pelvic
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CN103908628A (en
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於永梅
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Abstract

The present invention provides a kind of herbal enema medicament treating chronic pelvic inflammatory disease and preparation method thereof, it comprises the raw material of following parts by weight: the Radix Astragali: 25 35 parts, Ramulus Cinnamomi: 10 14 parts, Radix Salviae Miltiorrhizae: 10 14 parts, Radix Paeoniae Rubra: 10 14 parts, Fructus Forsythiae: 12 18 parts, Caulis Sargentodoxae: 25 35 parts, Caulis Spatholobi: 25 35 parts, Herba Patriniae: 17 23 parts, Rhizoma Sparganii: 10 15 parts, Rhizoma Curcumae: 10 15 parts, Spina Gleditsiae: 10 15 parts, the Radix Angelicae Dahuricae: 10 15 parts, Squama Manis preparata: 8 12 parts, Herba speranskiae tuberculatae: 15 25 parts, Fructus Liquidambaris: 10 15 parts.Preparation method is to take the crude drug of above-mentioned parts by weight to add suitable quantity of water and soak 25 35 minutes, decocts 2 times, the 1st 1.8 2.2h, 2nd 0.8 1.2h, collecting decoction, stand 22 26h, filter, take supernatant, be concentrated into 180 220 parts, add sodium benzoate 0.4 1.0 parts, ethyl hydroxybenzoate 0.04 0.10 parts, boil and make dissolving, filter, subpackage, sterilizing, thus obtaining the product.The lower abdomen pain that chronic pelvic inflammatory disease is caused by the present invention, lumbosacral aching pain, uterine activity is limited, and adnexa thickens, increases slightly, pelvic hydrops, cyst of pelvic cavity, and Infertility caused by fallopian tube obstruction has obvious therapeutic effect.

Description

A kind of herbal enema medicament treating chronic pelvic inflammatory disease and preparation method thereof
(1) technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, specifically one treats chronic pelvic inflammatory disease Herbal enema medicament and preparation method thereof.
(2) background technology
Chronic pelvic inflammatory disease is common gynecological disease, frequently-occurring disease, has course of disease length, recurrent exerbation, delay difficulty more Feature, has a strong impact on the quality of life of patient, even causes fallopian tube adhesion, obstruction to cause infertile.Doctor trained in Western medicine Antibiotic therapy short-term is effective, but relapse rate is high.The many employings of the traditional Chinese medical science " heat-clearing and toxic substances removing " " blood circulation promoting and blood stasis dispelling " " dissipates Knot disappears " method for the treatment of of " regulating QI to relieve pain " carries out Comprehensive Treatment.
(3) summary of the invention
The technical assignment of the present invention is for the deficiencies in the prior art, it is provided that a kind of treat in chronic pelvic inflammatory disease Medicine coloclysis medicament and preparation method thereof.
The herbal enema medicament of the treatment chronic pelvic inflammatory disease of the present invention is based on traditional Chinese medical science traditional medical theory, " to hold up The most eliminating evil " be principle, with the Radix Astragali, Ramulus Cinnamomi, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Fructus Forsythiae, Caulis Sargentodoxae, Caulis Spatholobi, Herba Patriniae, Rhizoma Sparganii, Rhizoma Curcumae, Spina Gleditsiae, the Radix Angelicae Dahuricae, Squama Manis preparata, Herba speranskiae tuberculatae and Fructus Liquidambaris are raw material, are joined by science 5 Chinese medicine preparation preparing the present invention.
The side of above-mentioned each material composition solves and primary efficacy is:
The Radix Astragali: sweet in the mouth, slightly warm in nature.Return spleen, lung meridian.Spleen reinforcing lung qi, ascending up spleen-Qi and Yang, benefit defends consolidating superficial resistance, sharp Urine, promoting pus discharge and tissue regeneration strengthening.The modern pharmacological research Radix Astragali can promote organism metabolism, strengthens and regulates body's immunity.
Ramulus Cinnamomi: acrid in the mouth, sweet, warm in nature.Return lung, the heart, kidney, Liver Channel.Promoting the flow of QI-blood by warming the meridian, temperature aid yang qi.With The effect of QI invigorating warming the meridian for promoting the flow of YANG QI played altogether by the Radix Astragali.This product enters arbitrarily blood system, with the cold coagulation in temperature scattered pulse, can declare again and lead work Blood medicine, to strengthen the effect of blood circulation promoting and blood stasis dispelling.
Radix Salviae Miltiorrhizae: acrid in the mouth, hardship, cold nature.GUIXIN, Liver Channel.Blood circulation promoting and blood stasis dispelling, removing heat from blood eliminating carbuncle.For blood stasis Caused various disease conditions.
Radix Paeoniae Rubra: bitter in the mouth, pungent, cold nature.Return liver, heart channel.Clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.
Fructus Forsythiae: bitter in the mouth, micro-pungent, cold in nature.Return lung, stomach, the heart, small intestine meridian.Heat-clearing and toxic substances removing, dispelling wind heat, Clear away heart-fire heat.
Caulis Sargentodoxae: bitter in the mouth, pungent, cold nature.Return large intestine, Liver Channel.Heat-clearing and toxic substances removing, promoting blood circulation and stopping pain.For intestinal Carbuncle stomachache or blood-stasis internal-depression, woman in menstrual period imbalance, dysmenorrhea etc..
Caulis Spatholobi: acrid in the mouth, hardship, sweet, warm in nature.Return Liver Channel.Blood circulation promoting and enriching, relaxing muscles and tendons and activating QI and blood in the collateral.For menstruation Uncomfortable, dysmenorrhea, amenorrhea or postpartum stagnation stomachache.
Herba Patriniae: bitter in the mouth, pungent, cold nature.Return large intestine, liver, stomach warp.Heat-clearing and toxic substances removing, promoting blood circulation and stopping pain. For cards such as acute appendicitis, lung abscess, swelling pain cause by skin sore and carbuncle, the stagnant stomachache of the stasis of blood.
Rhizoma Sparganii: acrid in the mouth, hardship, property is put down.Return liver, spleen channel.Removing blood stasis, promoting the circulation of QI to relieve pain.For blood stasis or Abdominal mass accumulation, amenorrhea and trusted subordinate's stasis of blood pain caused by stagnation of QI and blood.Normal and Rhizoma Curcumae mutual reinforcement between is use.
Rhizoma Curcumae: acrid in the mouth, hardship, warm in nature.Return liver, spleen channel.Removing blood stasis, promoting the circulation of QI to relieve pain.For blood stasis or Abdominal mass accumulation, amenorrhea and trusted subordinate's stasis of blood pain caused by stagnation of QI and blood.Normal and Rhizoma Sparganii mutual reinforcement between is use.
Spina Gleditsiae: acrid in the mouth, warm in nature.Return lung, Liver Channel.Blood circulation promoting medicine, dispel-wind drug.Cure mainly swollen ulcer drug, scrofula Scrofula, skin ulcer rash stubborn dermatitis, puerperal hypogalactia, placenta retention, leprosy.
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature.Attach to the lung and stomach meridians.Expelling pathogenic wind from the body surface, pain relieving, clearing the nasal passage, dampness.This product Pungent perfume (or spice) and the inclined warm-dryness syndrome of property, control cold-damp bet, leukorrhagia, with cold expelling, dampness, and can rise the positive bright clearing heat in QI system of act With leukorrhagia stopping.
Squama Manis: acrid in the mouth, salty, cold nature.Blood circulation promoting and blood stasis dispelling, stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis.For abdominal mass Accumulation, amenorrhea due to stagnation of blood and rheumatic arthralgia etc..This product is good at walking to alter, and the special row of property dissipates, and blood circulation promoting and blood stasis dispelling power is relatively strong, Inside reach zang-fu differentiation, invigorated blood circulation by it and reach burst hard eliminating stagnation, the effect of dredge the meridian passage.
Herba speranskiae tuberculatae: acrid in the mouth, warm in nature.Return Liver Channel.Expelling wind and removing dampness, promoting blood circulation to remove blood stasis.For rheumatic arthralgia, muscle Meat contracture, traumatic injury, sore swollen toxin.
Fructus Liquidambaris: bitter in the mouth, micro-pungent, property is put down.Return liver, stomach, bladder warp.Micro-fragrant row dissipates.Soothing the liver circulation of qi promoting, Promoting blood circulation to remove obstruction in the collateral.
The technical solution adopted for the present invention to solve the technical problems is:
A kind of herbal enema medicament treating chronic pelvic inflammatory disease, it comprises the raw material of following parts by weight:
The Radix Astragali: 25-35 part, Ramulus Cinnamomi: 10-14 part, Radix Salviae Miltiorrhizae: 10-14 part, Radix Paeoniae Rubra: 10-14 part,
Fructus Forsythiae: 12-18 part, Caulis Sargentodoxae: 25-35 part, Caulis Spatholobi: 25-35 part, Herba Patriniae: 17-23 part,
Rhizoma Sparganii: 10-15 part, Rhizoma Curcumae: 10-15 part, Spina Gleditsiae: 10-15 part, the Radix Angelicae Dahuricae: 10-15 part,
Squama Manis preparata: 8-12 part, Herba speranskiae tuberculatae: 15-25 part, Fructus Liquidambaris: 10-15 part.
Further, a kind of herbal enema medicament treating chronic pelvic inflammatory disease, it comprises following preferred weight part The raw material of number:
The Radix Astragali: 28-32 part, Ramulus Cinnamomi: 11-13 part, Radix Salviae Miltiorrhizae: 11-13 part, Radix Paeoniae Rubra: 11-13 part,
Fructus Forsythiae: 14-16 part, Caulis Sargentodoxae: 28-32 part, Caulis Spatholobi: 28-32 part, Herba Patriniae: 19-21 part,
Rhizoma Sparganii: 11-13 part, Rhizoma Curcumae: 11-13 part, Spina Gleditsiae: 11-13 part, the Radix Angelicae Dahuricae: 11-13 part,
Squama Manis preparata: 9-11 part, Herba speranskiae tuberculatae: 18-22 part, Fructus Liquidambaris: 11-13 part.
Further, a kind of herbal enema medicament treating chronic pelvic inflammatory disease, it comprises following optimum weight The raw material of number:
The Radix Astragali: 30 parts, Ramulus Cinnamomi: 12 parts, Radix Salviae Miltiorrhizae: 12 parts, Radix Paeoniae Rubra: 12 parts, Fructus Forsythiae: 15 parts, red Rattan: 30 parts, Caulis Spatholobi: 30 parts, Herba Patriniae: 20 parts, Rhizoma Sparganii: 12 parts, Rhizoma Curcumae: 12 parts, Fructus Gleditsia Thorn: 12 parts, the Radix Angelicae Dahuricae: 12 parts, Squama Manis preparata: 10 parts, Herba speranskiae tuberculatae: 20 parts, Fructus Liquidambaris: 12 parts.
The preparation method of the herbal enema medicament of above-mentioned treatment chronic pelvic inflammatory disease, the method is according to following steps Carry out:
Take the crude drug of above-mentioned parts by weight to add suitable quantity of water and soak 25-35 minute, decoct 2 times, the 1st time 1.8-2.2h, the 2nd 0.8-1.2h, collecting decoction, stand 22-26h, filter, take supernatant, concentrate To 180-220 part, add sodium benzoate 0.4-1.0 part, ethyl hydroxybenzoate 0.04-0.10 part, boil make molten Solve, filter, subpackage, sterilizing, thus obtaining the product.
Using method:
Retention enema the most just before going to bed 1 time, each 200ml, 10 days 1 courses for the treatment of, it is used in conjunction three courses for the treatment of.Warp Phase disables.
A kind of herbal enema medicament treating chronic pelvic inflammatory disease of the present invention and preparation method thereof and prior art phase Ratio, produced by provide the benefit that:
1) the herbal enema medicament compatibility of the treatment chronic pelvic inflammatory disease of the present invention is scientific and reasonable, preparation technology simple, The lower abdomen pain that chronic pelvic inflammatory disease is caused, lumbosacral aching pain, uterine activity is limited, and adnexa thickens, increases slightly, Pelvic hydrops, cyst of pelvic cavity, and Infertility caused by fallopian tube obstruction have obvious therapeutic effect.And this preparation has Effective ingredient concentration is high, easy to use, do not find adverse effect and feature that clinical efficacy is good.
2) present invention uses the method for " QI invigorating warming the meridian for promoting the flow of YANG QI, activating blood circulation to dissipate blood stasis and dredge the collateral ", uses coloclysis to be administered, can So that the through sick institute of medicine, improve pelvic cavity blood supply, promote the absorption of inflammatory seep, the pine of adhesion organization Solve, make pathological changes be improved rapidly.From the angle analysis of pharmaceutics, first pass effect can be avoided, it is to avoid oral Stimulation to Stomach duodenum.
(4) detailed description of the invention
Below in conjunction with implement 1-7 to the present invention herbal enema medicament treating chronic pelvic inflammatory disease and preparation method thereof It is described in detail.
In embodiment 1-7, the weight proportion (unit: gram) of each raw material is as follows:
Its preparation method is:
Take the crude drug of above-mentioned parts by weight to add suitable quantity of water and soak 25-35 minute, decoct 2 times, the 1st time 1.8-2.2h, the 2nd 0.8-1.2h, collecting decoction, stand 22-26h, filter, take supernatant, concentrate To 180-220 part, add sodium benzoate 0.4-1.0 part, ethyl hydroxybenzoate 0.04-0.10 part, boil make molten Solve, filter, subpackage, sterilizing, thus obtaining the product.
It is presented herein below and the present invention is treated the clinical experiment that the herbal enema medicament of chronic pelvic inflammatory disease is carried out:
The present inventor carries out clinical observation, age 22--48 year, the course of disease 2 to 120 example undergoing chronic pelvic inflammation Individual month-7 years, the medicine of the application of the invention, 2-3 the course for the treatment of of general medication, 111 people cured, control More rate reaches 92.5%, and 116 people are effective, and effective percentage is 97.5%.
Typical clinical case
Case 1, Liu, female, 35 years old, people from Xuecheng District, Zaozhuang City, just comes here on November 4th, 2012 Examining, chronic pelvic inflammatory disease recurrent exerbation 5 years, existing disease sees lower abdomen dull pain, the soreness of waist, and profuse leukorrhea yellow skin has abnormal flavour, Menstruation color is dim block.Gynecologial examination: lifting pain, position after the body of palace, limitation of activity, bilateral adnexa thickens. It is diagnosed as pelvic inflammatory disease, after giving 3 courses for the treatment of of this medicine coloclysis, transference cure.
Case 2, Zhang, female, 32 years old, Weishan County summer town Xie Qiao people from village, comes here on January 16th, 2013 Medical, readme sagging distention in the smaller abdomen pain, profuse leukorrhea, the soreness of waist aches, tired postemphasis, does not practises contraception and does not becomes pregnant 2 Nian Duo, through ultrasound diagnosis right adnexal cyst 3.3 × 2.2 × 3.1cm, after giving 3 courses for the treatment of of this medicine coloclysis, abdomen Pain disappears, through B ultrasonic detection recovery from illness.In April, 2013, menolipsis was become pregnant.
Case 3, Guo, female, 43 years old, joyous people from cities and towns, Weishan County, just comes here on April 20th, 2013 Examining, companion menoxenia half a year its clinical manifestation lower abdomen dull pain several months, less effective after many places are treated, through B Super check that left attachment area is visited and 4.3 × 3.2 × 2.5cm low echo enclosed mass, after giving 3 courses for the treatment of of this medicine coloclysis, Transference cure, through B ultrasonic detection recovery from illness.
Case 4, ancestor, female, 27 years old, Weishan County Zhao Yang people from subdistrict office, within 2013, JIUYUE was come on the 23rd Go to a doctor in here, readme sagging distention in the smaller abdomen pain more than 20 day, accompanies the soreness of waist, through ultrasound diagnosis pelvic hydrops 18mm, Give transference cure after 2 courses for the treatment of of this medicine coloclysis, through B ultrasonic detection recovery from illness.
Case 5, Feng, female, 40 years old, Zhang Wang people from town, Tengzhou City, come here on July 11st, 2013 and go to a doctor, Secondary infertility 2 years, gynecologial examination: pudendum (-), vagina is unobstructed, a little thick secretions, and cervix uteri is light Degree erosion, position after the body of palace, normal size, tenderness, bilateral adnexa lamellar thickens.Hysterosalpingography shows: Lifting on bilateral salpingo, pelviography agent disperse is limited to.After giving 3 courses for the treatment of of this medicine coloclysis, pelvic cavity sign Disappear.On October 10th, 2013, menolipsis 48 days, showed through ultrasound diagnosis: early pregnancy.

Claims (4)

1. the herbal enema medicament treating chronic pelvic inflammatory disease, it is characterised in that it is made up of the crude drug of following parts by weight:
The Radix Astragali: 25-35 part, Ramulus Cinnamomi: 10-14 part, Radix Salviae Miltiorrhizae: 10-14 part, Radix Paeoniae Rubra: 10-14 part,
Fructus Forsythiae: 12-18 part, Caulis Sargentodoxae: 25-35 part, Caulis Spatholobi: 25-35 part, Herba Patriniae: 17-23 part,
Rhizoma Sparganii: 10-15 part, Rhizoma Curcumae: 10-15 part, Spina Gleditsiae: 10-15 part, the Radix Angelicae Dahuricae: 10-15 part,
Squama Manis preparata: 8-12 part, Herba speranskiae tuberculatae: 15-25 part, Fructus Liquidambaris: 10-15 part.
A kind of herbal enema medicament treating chronic pelvic inflammatory disease the most according to claim 1, it is characterised in that it is made up of the crude drug of following parts by weight:
The Radix Astragali: 28-32 part, Ramulus Cinnamomi: 11-13 part, Radix Salviae Miltiorrhizae: 11-13 part, Radix Paeoniae Rubra: 11-13 part,
Fructus Forsythiae: 14-16 part, Caulis Sargentodoxae: 28-32 part, Caulis Spatholobi: 28-32 part, Herba Patriniae: 19-21 part,
Rhizoma Sparganii: 11-13 part, Rhizoma Curcumae: 11-13 part, Spina Gleditsiae: 11-13 part, the Radix Angelicae Dahuricae: 11-13 part,
Squama Manis preparata: 9-11 part, Herba speranskiae tuberculatae: 18-22 part, Fructus Liquidambaris: 11-13 part.
A kind of herbal enema medicament treating chronic pelvic inflammatory disease the most according to claim 1, it is characterised in that it is made up of the crude drug of following parts by weight:
The Radix Astragali: 30 parts, Ramulus Cinnamomi: 12 parts, Radix Salviae Miltiorrhizae: 12 parts, Radix Paeoniae Rubra: 12 parts, Fructus Forsythiae: 15 parts, Caulis Sargentodoxae: 30 parts, Caulis Spatholobi: 30 parts, Herba Patriniae: 20 parts, Rhizoma Sparganii: 12 parts, Rhizoma Curcumae: 12 parts, Spina Gleditsiae: 12 parts, the Radix Angelicae Dahuricae: 12 parts, Squama Manis preparata: 10 parts, Herba speranskiae tuberculatae: 20 parts, Fructus Liquidambaris: 12 parts.
4. the preparation method of the herbal enema medicament treating chronic pelvic inflammatory disease as described in claim 1,2 or 3, it is characterised in that: the method follows the steps below:
The crude drug taking above-mentioned parts by weight adds suitable quantity of water immersion 25-35 minute, decocts 2 times, the 1st 1.8-2.2h, 2nd 0.8-1.2h, collecting decoction, stand 22-26h, filter, take supernatant, be concentrated into 180-220 part, add sodium benzoate 0.4-1.0 part, ethyl hydroxybenzoate 0.04-0.10 part, boil and make dissolving, filter, subpackage, sterilizing, thus obtaining the product.
CN201410095029.2A 2014-03-17 2014-03-17 A kind of herbal enema medicament treating chronic pelvic inflammatory disease and preparation method thereof Expired - Fee Related CN103908628B (en)

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CN104587403A (en) * 2015-01-29 2015-05-06 罗舒引 Traditional Chinese medicine composition for treating gynecological inflammations
CN104740529A (en) * 2015-03-11 2015-07-01 周炳秀 Traditional Chinese medicine enema prescription for treating pelvic inflammation
CN105749037A (en) * 2016-03-30 2016-07-13 宜都市中医医院 Traditional Chinese medicine composition for treating chronic pelvic inflammatory disease and preparation method and application thereof
CN107715013A (en) * 2017-10-16 2018-02-23 冯丽华 A kind of infertile bowel lavage prescription for salpingemphraxis and preparation method thereof
CN112618683A (en) * 2021-01-14 2021-04-09 佛山市欣康迈科技有限公司 Medicine for treating fallopian tube obstruction and preparation method thereof
CN113440566A (en) * 2021-08-20 2021-09-28 重庆市中医院 Enema medicine for treating pelvic inflammation and preparation method thereof
CN117159674B (en) * 2023-11-03 2024-01-09 云南中医药大学 Gynecological traditional Chinese medicine composition for treating damp-heat stasis syndrome

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