CN103908628A - A traditional Chinese medicine enema medicament used for treating chronic pelvic inflammation and a preparing method thereof - Google Patents
A traditional Chinese medicine enema medicament used for treating chronic pelvic inflammation and a preparing method thereof Download PDFInfo
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- CN103908628A CN103908628A CN201410095029.2A CN201410095029A CN103908628A CN 103908628 A CN103908628 A CN 103908628A CN 201410095029 A CN201410095029 A CN 201410095029A CN 103908628 A CN103908628 A CN 103908628A
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Abstract
The invention provides a traditional Chinese medicine enema medicament used for treating chronic pelvic inflammation and a preparing method thereof. The medicament comprises following raw materials by weight: 25-35 parts of radix astragali, 10-14 parts of cassia twig, 10-14 parts of red sage root, 10-14 parts of red peony root, 12-18 parts of fructus forsythiae, 25-35 parts of sargentodoxa vine, 25-35 parts of spatholobus stem, 17-23 parts of herba patriniae, 10-15 parts of common burreed rhizome, 10-15 parts of zedoary turmeric, 10-15 parts of Chinese honeylocust spine, 10-15 parts of dahurian angelica root, 8-12 parts of parched pangolin scales, 15-25 parts of herb of garden balsam and 10-15 parts of sweetgum fruit. The method includes: adding a proper amount of water into the raw material medicines of the weight parts mentioned above, dipping for 25-35 min, decocting for two times with the first decocting time being 1.8-2.2 h and the second decocting time being 0.8-1.2 h, combining the decoction liquids, allowing the mixture to stand for 22-26 h, filtering to obtain liquid supernatant, concentrating the liquid supernatant to 180-220 parts, adding 0.4-1.0 part of sodium benzoate and 0.04-0.10 part of ethylparaben, boiling for dissolution, filtering, subpackaging and sterilizing. The medicament has significant treating effects for lower-abdomen pain, lumbosacral aching, restricted uterus movement, adnexa uteri thickening, pelvic effusion, pelvic cysts, and fallopian tube obstructive infertility which are caused by the chronic pelvic inflammation.
Description
(1) technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, specifically a kind of herbal enema medicament for the treatment of chronic pelvic inflammatory disease and preparation method thereof.
(2) background technology
Chronic pelvic inflammatory disease is common gynecological disease, frequently-occurring disease, has the course of disease and grows, repeatedly shows effect, delays the difficult feature healing, and has a strong impact on patient's quality of life, even causes that fallopian tube adhesion, obstruction cause infertile.Doctor trained in Western medicine antibiotic therapy short-term is effective, but relapse rate is high.The traditional Chinese medical science adopts the method for the treatment of of " heat-clearing and toxic substances removing " " blood circulation promoting and blood stasis dispelling " " dispersing accumulated pathogens to resolve the mass " " regulating QI to relieve pain " to carry out Comprehensive Treatment more.
(3) summary of the invention
Technical assignment of the present invention is for the deficiencies in the prior art, and a kind of herbal enema medicament for the treatment of chronic pelvic inflammatory disease and preparation method thereof is provided.
The herbal enema medicament for the treatment of chronic pelvic inflammatory disease of the present invention is taking traditional Chinese medical science traditional medical theory as basis, taking " strengthening vital QI to eliminate pathogenic factors " as principle, taking the Radix Astragali, Ramulus Cinnamomi, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Fructus Forsythiae, Caulis Sargentodoxae, Caulis Spatholobi, Herba Patriniae, Rhizoma Sparganii, Rhizoma Curcumae, Spina Gleditsiae, the Radix Angelicae Dahuricae, Squama Manis preparata, Herba speranskiae tuberculatae and Fructus Liquidambaris as raw material, make Chinese medicine preparation of the present invention by science compatibility.
The side of above-mentioned each material composition separates and main effect is:
The Radix Astragali: sweet in the mouth, slightly warm in nature.Return spleen, lung meridian.Spleen reinforcing lung qi, ascending up spleen-Qi and Yang, benefit is defended consolidating superficial resistance, diuresis, promoting pus discharge and tissue regeneration strengthening.The modern pharmacological research Radix Astragali can promote organism metabolism, strengthens and adjusting body's immunity.
Ramulus Cinnamomi: acrid in the mouth, sweet, warm in nature.Return lung, the heart, kidney, Liver Channel.Promoting the flow of QI-blood by warming the meridian, warm aid yang qi.The effect of playing altogether QI invigorating warming the meridian for promoting the flow of YANG QI with the Radix Astragali.This product is entered arbitrarily blood system, with the cold coagulation in warm scattered pulse, can declare and lead blood circulation promoting medicine again, to strengthen the effect of blood circulation promoting and blood stasis dispelling.
Radix Salviae Miltiorrhizae: acrid in the mouth, hardship, cold nature.GUIXIN, Liver Channel.Blood circulation promoting and blood stasis dispelling, removing heat from blood eliminating carbuncle.For the various disease conditions due to blood stasis.
Radix Paeoniae Rubra: bitter in the mouth, pungent, cold nature.Return liver, heart channel.Clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.
Fructus Forsythiae: bitter in the mouth, micro-pungent, cold in nature.Return lung, stomach, the heart, small intestine meridian.Heat-clearing and toxic substances removing, dispelling wind heat, heat clears away heart-fire.
Caulis Sargentodoxae: bitter in the mouth, pungent, cold nature.Return large intestine, Liver Channel.Heat-clearing and toxic substances removing, promoting blood circulation and stopping pain.For abdominalgia with intestinal abscess or blood-stasis internal-depression, woman in menstrual period imbalance, dysmenorrhea etc.
Caulis Spatholobi: acrid in the mouth, hardship, sweet, warm in nature.Return Liver Channel.Blood circulation promoting and enriching, relaxing muscles and tendons and activating QI and blood in the collateral.For menoxenia, dysmenorrhea, amenorrhea or postpartum stagnation stomachache.
Herba Patriniae: bitter in the mouth, pungent, cold nature.Return large intestine, liver, stomach warp.Heat-clearing and toxic substances removing, promoting blood circulation and stopping pain.For acute appendicitis, lung abscess, swelling pain cause by skin sore and carbuncle, the cards such as the stagnant stomachache of the stasis of blood.
Rhizoma Sparganii: acrid in the mouth, hardship, property is flat.Return liver, spleen channel.Removing blood stasis, promoting the circulation of QI to relieve pain.For lumps in the chest and abdomen, amenorrhea and trusted subordinate's stasis of blood pain due to blood stasis or stagnation of QI and blood.Normal and Rhizoma Curcumae mutual reinforcement between is use.
Rhizoma Curcumae: acrid in the mouth, hardship, warm in nature.Return liver, spleen channel.Removing blood stasis, promoting the circulation of QI to relieve pain.For lumps in the chest and abdomen, amenorrhea and trusted subordinate's stasis of blood pain due to blood stasis or stagnation of QI and blood.Normal and Rhizoma Sparganii mutual reinforcement between is use.
Spina Gleditsiae: acrid in the mouth, warm in nature.Return lung, Liver Channel.Blood circulation promoting medicine, medicine dispels the wind.Cure mainly swollen ulcer drug, scrofula, skin ulcer rash stubborn dermatitis, puerperal hypogalactia, placenta retention, leprosy.
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature.Attach to the lung and stomach meridians.Expelling pathogenic wind from the body surface, pain relieving, clearing the nasal passage, dampness.The pungent perfume (or spice) of this product and the inclined to one side warm-dryness syndrome of property, control cold-damp bet, and leukorrhagia can cold expelling, dampness, and the bright clearing heat in QI system of elevate a turnable ladder sun is with leukorrhagia stopping.
Squama Manis: acrid in the mouth, salty, cold nature.Blood circulation promoting and blood stasis dispelling, the stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis.Yong Yu lumps in the chest and abdomen, amenorrhea due to stagnation of blood and rheumatic arthralgia etc.This product is good at walking to alter, and property specially row is loose, and blood circulation promoting and blood stasis dispelling power is stronger, inside reaches internal organs meridians, is invigorated blood circulation and is reached the effect of burst hard eliminating stagnation, dredge the meridian passage by it.
Herba speranskiae tuberculatae: acrid in the mouth, warm in nature.Return Liver Channel.Expelling wind and removing dampness, promoting blood circulation to remove blood stasis.For rheumatic arthralgia, muscles contracture, traumatic injury, sore swollen toxin.
Fructus Liquidambaris: bitter in the mouth, micro-pungent, property is flat.Return liver, stomach, urinary bladder channel.Micro-fragrant row is loose.Soothing the liver circulation of qi promoting, promoting blood circulation to remove obstruction in the collateral.
The technical solution adopted for the present invention to solve the technical problems is:
Treat a herbal enema medicament for chronic pelvic inflammatory disease, the raw material that it comprises following parts by weight:
The Radix Astragali: 25-35 part, Ramulus Cinnamomi: 10-14 part, Radix Salviae Miltiorrhizae: 10-14 part, Radix Paeoniae Rubra: 10-14 part,
Fructus Forsythiae: 12-18 part, Caulis Sargentodoxae: 25-35 part, Caulis Spatholobi: 25-35 part, Herba Patriniae: 17-23 part,
Rhizoma Sparganii: 10-15 part, Rhizoma Curcumae: 10-15 part, Spina Gleditsiae: 10-15 part, the Radix Angelicae Dahuricae: 10-15 part,
Squama Manis preparata: 8-12 part, Herba speranskiae tuberculatae: 15-25 part, Fructus Liquidambaris: 10-15 part.
Further, a kind of herbal enema medicament for the treatment of chronic pelvic inflammatory disease, the raw material that it comprises following preferred weight umber:
The Radix Astragali: 28-32 part, Ramulus Cinnamomi: 11-13 part, Radix Salviae Miltiorrhizae: 11-13 part, Radix Paeoniae Rubra: 11-13 part,
Fructus Forsythiae: 14-16 part, Caulis Sargentodoxae: 28-32 part, Caulis Spatholobi: 28-32 part, Herba Patriniae: 19-21 part,
Rhizoma Sparganii: 11-13 part, Rhizoma Curcumae: 11-13 part, Spina Gleditsiae: 11-13 part, the Radix Angelicae Dahuricae: 11-13 part,
Squama Manis preparata: 9-11 part, Herba speranskiae tuberculatae: 18-22 part, Fructus Liquidambaris: 11-13 part.
Further, a kind of herbal enema medicament for the treatment of chronic pelvic inflammatory disease, the raw material that it comprises following optimum weight umber:
The Radix Astragali: 30 parts, Ramulus Cinnamomi: 12 parts, Radix Salviae Miltiorrhizae: 12 parts, Radix Paeoniae Rubra: 12 parts, Fructus Forsythiae: 15 parts, Caulis Sargentodoxae: 30 parts, Caulis Spatholobi: 30 parts, Herba Patriniae: 20 parts, Rhizoma Sparganii: 12 parts, Rhizoma Curcumae: 12 parts, Spina Gleditsiae: 12 parts, the Radix Angelicae Dahuricae: 12 parts, Squama Manis preparata: 10 parts, Herba speranskiae tuberculatae: 20 parts, Fructus Liquidambaris: 12 parts.
The preparation method of the herbal enema medicament of above-mentioned treatment chronic pelvic inflammatory disease, the method is carried out according to following steps:
The crude drug of getting above-mentioned parts by weight adds suitable quantity of water and soaks 25-35 minute, decocts the 1st 1.8-2.2h 2 times, the 2nd 0.8-1.2h, collecting decoction, leaves standstill 22-26h, filter, get supernatant, be concentrated into 180-220 part, add sodium benzoate 0.4-1.0 part, ethyl hydroxybenzoate 0.04-0.10 part, boil and make to dissolve, filter subpackage, sterilizing and get final product.
Using method:
Retention enema just before going to bed 1 time every night, each 200ml, 10 days 1 courses for the treatment of, is used in conjunction three courses for the treatment of.Stop using menstrual period.
Compared with prior art, the beneficial effect producing is a kind of herbal enema medicament for the treatment of chronic pelvic inflammatory disease of the present invention and preparation method thereof:
1) the herbal enema medicament compatibility for the treatment of chronic pelvic inflammatory disease of the present invention is scientific and reasonable, preparation technology is simple, the lower abdomen pain that chronic pelvic inflammatory disease is caused, lumbosacral aching pain, uterine activity is limited, adnexa thickens, increases thick, pelvic hydrops, cyst of pelvic cavity, and obstructive oviduct is infertile an obvious therapeutic effect.And this preparation have effective ingredient concentration high, easy to use, do not find adverse effect and the good feature of clinical efficacy.
2) the present invention uses the method for " QI invigorating warming the meridian for promoting the flow of YANG QI, activating blood circulation to dissipate blood stasis and dredge the collateral ", adopts coloclysis administration, can make the medicine sick institute that go directly, improves pelvic cavity blood supply, and absorption that promotion inflammation is oozed out, adhesion organization loosen, and pathological changes is improved rapidly.From the angle analysis of pharmaceutics, can avoid first pass effect, avoid the oral stimulation to Stomach duodenum.
(4) detailed description of the invention
Be elaborated below in conjunction with implementing 1-7 herbal enema medicament to treatment chronic pelvic inflammatory disease of the present invention and preparation method thereof.
The weight proportion of each raw material in embodiment 1-7 (unit: gram) as follows:
Its preparation method is:
The crude drug of getting above-mentioned parts by weight adds suitable quantity of water and soaks 25-35 minute, decocts the 1st 1.8-2.2h 2 times, the 2nd 0.8-1.2h, collecting decoction, leaves standstill 22-26h, filter, get supernatant, be concentrated into 180-220 part, add sodium benzoate 0.4-1.0 part, ethyl hydroxybenzoate 0.04-0.10 part, boil and make to dissolve, filter subpackage, sterilizing and get final product.
The clinical experiment that the herbal enema medicament for the treatment of chronic pelvic inflammatory disease of the present invention is carried out below:
The inventor carries out clinical observation to 120 routine undergoing chronic pelvic inflammation, age 22--48 year, and the course of disease 2 months-7 years, the medicine of the application of the invention, general medication 2-3 course for the treatment of, 111 people's healings, it is effective that cure rate reaches 92.5%, 116 people, and effective percentage is 97.5%.
Typical clinical case
Case 1, Liu, female, 35 years old, people from Xuecheng District, Zaozhuang City, came here on November 4th, 2012 medical, and chronic pelvic inflammatory disease is shown effect 5 years repeatedly, and existing disease is seen lower abdomen dull pain, the soreness of waist, profuse leukorrhea yellow skin has abnormal flavour, and menstruation color is dim piece.Gynecologial examination: lifting pain, position after the body of palace, limitation of activity, bilateral adnexa thickens.Be diagnosed as pelvic inflammatory disease, give after 3 courses for the treatment of of this medicine coloclysis transference cure.
Case 2, Zhang, female, 32 years old, Weishan County summer town Xie Qiao people from village, comes here on January 16th, 2013 medical, readme sagging distention in the smaller abdomen pain, profuse leukorrhea, soreness of waist pain, tired postemphasis, contraception was not become pregnant more than 2 years, through right adnexal cyst 3.3 × 2.2 × 3.1cm of ultrasound diagnosis, give after 3 courses for the treatment of of this medicine coloclysis, stomachache disappears, and detects recovery from illness through B ultrasonic.In April, 2013, menolipsis was become pregnant.
Case 3, Guo, female, 43 years old, joyous people from cities and towns in Weishan County, came here on April 20th, 2013 medical, its companion menoxenia half a year clinical manifestation lower abdomen dull pain several months, after many places treatments, effect is not good enough, visits and the low echo enclosed mass of 4.3 × 3.2 × 2.5cm through the left attachment area of ultrasound diagnosis, gives after 3 courses for the treatment of of this medicine coloclysis, transference cure, detects recovery from illness through B ultrasonic.
Case 4, ancestor certain, female, 27 years old, Weishan County Zhao Yang people from subdistrict office, it is medical that JIUYUE in 2013 is come here on the 23rd, readme sagging distention in the smaller abdomen pain more than 20 day, companion's soreness of waist, through ultrasound diagnosis pelvic hydrops 18mm, give transference cure after 2 courses for the treatment of of this medicine coloclysis, detect recovery from illness through B ultrasonic.
Case 5, Feng, female, 40 years old, Zhang Wang people from town, Tengzhou City, came here on July 11st, 2013 medical, secondary infertility 2 years, gynecologial examination: pudendum (-), vagina is unobstructed, a little thick secretions, cervix uteri is slightly rotten to the corn, position after the body of palace, normal size, tenderness, bilateral adnexa lamellar thickens.Hysterosalpingography shows: on bilateral fallopian tube, lift pelviography agent disperse limitation.Give after 3 courses for the treatment of of this medicine coloclysis, pelvic cavity sign disappears.On October 10th, 2013, menolipsis 48 days, showed through ultrasound diagnosis: early pregnancy.
Claims (4)
1. a herbal enema medicament for the treatment of chronic pelvic inflammatory disease, is characterized in that, the raw material that it comprises following parts by weight:
The Radix Astragali: 25-35 part, Ramulus Cinnamomi: 10-14 part, Radix Salviae Miltiorrhizae: 10-14 part, Radix Paeoniae Rubra: 10-14 part,
Fructus Forsythiae: 12-18 part, Caulis Sargentodoxae: 25-35 part, Caulis Spatholobi: 25-35 part, Herba Patriniae: 17-23 part,
Rhizoma Sparganii: 10-15 part, Rhizoma Curcumae: 10-15 part, Spina Gleditsiae: 10-15 part, the Radix Angelicae Dahuricae: 10-15 part,
Squama Manis preparata: 8-12 part, Herba speranskiae tuberculatae: 15-25 part, Fructus Liquidambaris: 10-15 part.
2. a kind of herbal enema medicament for the treatment of chronic pelvic inflammatory disease according to claim 1, is characterized in that: the raw material that it comprises following parts by weight:
The Radix Astragali: 28-32 part, Ramulus Cinnamomi: 11-13 part, Radix Salviae Miltiorrhizae: 11-13 part, Radix Paeoniae Rubra: 11-13 part,
Fructus Forsythiae: 14-16 part, Caulis Sargentodoxae: 28-32 part, Caulis Spatholobi: 28-32 part, Herba Patriniae: 19-21 part,
Rhizoma Sparganii: 11-13 part, Rhizoma Curcumae: 11-13 part, Spina Gleditsiae: 11-13 part, the Radix Angelicae Dahuricae: 11-13 part,
Squama Manis preparata: 9-11 part, Herba speranskiae tuberculatae: 18-22 part, Fructus Liquidambaris: 11-13 part.
3. a kind of herbal enema medicament for the treatment of chronic pelvic inflammatory disease according to claim 1, is characterized in that: the raw material that it comprises following parts by weight:
The Radix Astragali: 30 parts, Ramulus Cinnamomi: 12 parts, Radix Salviae Miltiorrhizae: 12 parts, Radix Paeoniae Rubra: 12 parts, Fructus Forsythiae: 15 parts, Caulis Sargentodoxae: 30 parts, Caulis Spatholobi: 30 parts, Herba Patriniae: 20 parts, Rhizoma Sparganii: 12 parts, Rhizoma Curcumae: 12 parts, Spina Gleditsiae: 12 parts, the Radix Angelicae Dahuricae: 12 parts, Squama Manis preparata: 10 parts, Herba speranskiae tuberculatae: 20 parts, Fructus Liquidambaris: 12 parts.
4. a preparation method for the treatment of the herbal enema medicament of chronic pelvic inflammatory disease as described in claim 1,2 or 3, is characterized in that: the method is carried out according to following steps:
The crude drug of getting above-mentioned parts by weight adds suitable quantity of water and soaks 25-35 minute, decocts the 1st 1.8-2.2h 2 times, the 2nd 0.8-1.2h, collecting decoction, leaves standstill 22-26h, filter, get supernatant, be concentrated into 180-220 part, add sodium benzoate 0.4-1.0 part, ethyl hydroxybenzoate 0.04-0.10 part, boil and make to dissolve, filter subpackage, sterilizing and get final product.
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104587403A (en) * | 2015-01-29 | 2015-05-06 | 罗舒引 | Traditional Chinese medicine composition for treating gynecological inflammations |
| CN104740529A (en) * | 2015-03-11 | 2015-07-01 | 周炳秀 | Traditional Chinese medicine enema prescription for treating pelvic inflammation |
| CN105749037A (en) * | 2016-03-30 | 2016-07-13 | 宜都市中医医院 | Traditional Chinese medicine composition for treating chronic pelvic inflammatory disease and preparation method and application thereof |
| CN107715013A (en) * | 2017-10-16 | 2018-02-23 | 冯丽华 | A kind of infertile bowel lavage prescription for salpingemphraxis and preparation method thereof |
| CN112618683A (en) * | 2021-01-14 | 2021-04-09 | 佛山市欣康迈科技有限公司 | Medicine for treating fallopian tube obstruction and preparation method thereof |
| CN113440566A (en) * | 2021-08-20 | 2021-09-28 | 重庆市中医院 | Enema medicine for treating pelvic inflammation and preparation method thereof |
| CN117159674A (en) * | 2023-11-03 | 2023-12-05 | 云南中医药大学 | Gynecological traditional Chinese medicine composition for treating damp-heat stasis syndrome |
-
2014
- 2014-03-17 CN CN201410095029.2A patent/CN103908628B/en not_active Expired - Fee Related
Non-Patent Citations (2)
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| 卢英翔: "盆腔炎中医外治法应用概况", 《吉林中医药》, vol. 23, no. 8, 31 August 2003 (2003-08-31), pages 55 - 56 * |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104587403A (en) * | 2015-01-29 | 2015-05-06 | 罗舒引 | Traditional Chinese medicine composition for treating gynecological inflammations |
| CN104740529A (en) * | 2015-03-11 | 2015-07-01 | 周炳秀 | Traditional Chinese medicine enema prescription for treating pelvic inflammation |
| CN105749037A (en) * | 2016-03-30 | 2016-07-13 | 宜都市中医医院 | Traditional Chinese medicine composition for treating chronic pelvic inflammatory disease and preparation method and application thereof |
| CN107715013A (en) * | 2017-10-16 | 2018-02-23 | 冯丽华 | A kind of infertile bowel lavage prescription for salpingemphraxis and preparation method thereof |
| CN112618683A (en) * | 2021-01-14 | 2021-04-09 | 佛山市欣康迈科技有限公司 | Medicine for treating fallopian tube obstruction and preparation method thereof |
| CN113440566A (en) * | 2021-08-20 | 2021-09-28 | 重庆市中医院 | Enema medicine for treating pelvic inflammation and preparation method thereof |
| CN117159674A (en) * | 2023-11-03 | 2023-12-05 | 云南中医药大学 | Gynecological traditional Chinese medicine composition for treating damp-heat stasis syndrome |
| CN117159674B (en) * | 2023-11-03 | 2024-01-09 | 云南中医药大学 | Gynecological traditional Chinese medicine composition for treating damp-heat stasis syndrome |
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