CN101822320A - Vitamin water aqua and preparation method thereof - Google Patents
Vitamin water aqua and preparation method thereof Download PDFInfo
- Publication number
- CN101822320A CN101822320A CN201010179636A CN201010179636A CN101822320A CN 101822320 A CN101822320 A CN 101822320A CN 201010179636 A CN201010179636 A CN 201010179636A CN 201010179636 A CN201010179636 A CN 201010179636A CN 101822320 A CN101822320 A CN 101822320A
- Authority
- CN
- China
- Prior art keywords
- vitamin
- preparation
- water aqua
- solution
- parts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940088594 vitamin Drugs 0.000 title claims abstract description 137
- 229930003231 vitamin Natural products 0.000 title claims abstract description 137
- 235000013343 vitamin Nutrition 0.000 title claims abstract description 137
- 239000011782 vitamin Substances 0.000 title claims abstract description 137
- 150000003722 vitamin derivatives Chemical class 0.000 title claims abstract description 133
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title claims abstract description 77
- 238000002360 preparation method Methods 0.000 title claims description 44
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 24
- 239000002502 liposome Substances 0.000 claims abstract description 23
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 22
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims abstract description 22
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims abstract description 21
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims abstract description 12
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims abstract description 12
- 229930003316 Vitamin D Natural products 0.000 claims abstract description 12
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims abstract description 12
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 12
- 229930003448 Vitamin K Natural products 0.000 claims abstract description 12
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims abstract description 12
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 12
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 claims abstract description 12
- 239000011719 vitamin A Substances 0.000 claims abstract description 12
- 235000019155 vitamin A Nutrition 0.000 claims abstract description 12
- 239000011710 vitamin D Substances 0.000 claims abstract description 12
- 235000019166 vitamin D Nutrition 0.000 claims abstract description 12
- 150000003710 vitamin D derivatives Chemical class 0.000 claims abstract description 12
- 239000011709 vitamin E Substances 0.000 claims abstract description 12
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 12
- 229940046009 vitamin E Drugs 0.000 claims abstract description 12
- 235000019168 vitamin K Nutrition 0.000 claims abstract description 12
- 239000011712 vitamin K Substances 0.000 claims abstract description 12
- 150000003721 vitamin K derivatives Chemical class 0.000 claims abstract description 12
- 229940045997 vitamin a Drugs 0.000 claims abstract description 12
- 229940046008 vitamin d Drugs 0.000 claims abstract description 12
- 229940046010 vitamin k Drugs 0.000 claims abstract description 12
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 11
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims abstract description 11
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 11
- 238000006243 chemical reaction Methods 0.000 claims abstract description 11
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 claims abstract description 11
- 235000019152 folic acid Nutrition 0.000 claims abstract description 11
- 239000011724 folic acid Substances 0.000 claims abstract description 11
- 229960000304 folic acid Drugs 0.000 claims abstract description 11
- 239000002904 solvent Substances 0.000 claims abstract description 11
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 11
- 239000011718 vitamin C Substances 0.000 claims abstract description 11
- 239000002994 raw material Substances 0.000 claims abstract description 7
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 claims abstract description 6
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims abstract description 3
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims abstract description 3
- 229930003451 Vitamin B1 Natural products 0.000 claims abstract description 3
- 229930003471 Vitamin B2 Natural products 0.000 claims abstract description 3
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 claims abstract description 3
- 229960002477 riboflavin Drugs 0.000 claims abstract description 3
- 229960003495 thiamine Drugs 0.000 claims abstract description 3
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 claims abstract description 3
- 235000010374 vitamin B1 Nutrition 0.000 claims abstract description 3
- 239000011691 vitamin B1 Substances 0.000 claims abstract description 3
- 235000019164 vitamin B2 Nutrition 0.000 claims abstract description 3
- 239000011716 vitamin B2 Substances 0.000 claims abstract description 3
- 235000019158 vitamin B6 Nutrition 0.000 claims abstract description 3
- 239000011726 vitamin B6 Substances 0.000 claims abstract description 3
- 229940011671 vitamin b6 Drugs 0.000 claims abstract description 3
- 239000000243 solution Substances 0.000 claims description 42
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims description 38
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 38
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims description 24
- 239000003960 organic solvent Substances 0.000 claims description 17
- 239000007853 buffer solution Substances 0.000 claims description 16
- 235000012000 cholesterol Nutrition 0.000 claims description 12
- 238000007738 vacuum evaporation Methods 0.000 claims description 11
- NRJAVPSFFCBXDT-HUESYALOSA-N 1,2-distearoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCCCC NRJAVPSFFCBXDT-HUESYALOSA-N 0.000 claims description 10
- JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 claims description 10
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 10
- 235000020958 biotin Nutrition 0.000 claims description 10
- 239000011616 biotin Substances 0.000 claims description 10
- 229960002685 biotin Drugs 0.000 claims description 10
- 229960003511 macrogol Drugs 0.000 claims description 10
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 10
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 10
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 10
- 229940083466 soybean lecithin Drugs 0.000 claims description 10
- 239000000084 colloidal system Substances 0.000 claims description 7
- 238000001914 filtration Methods 0.000 claims description 7
- 239000012982 microporous membrane Substances 0.000 claims description 7
- 238000003801 milling Methods 0.000 claims description 7
- 239000011259 mixed solution Substances 0.000 claims description 7
- 230000035484 reaction time Effects 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims 1
- 230000004060 metabolic process Effects 0.000 abstract description 5
- 201000010099 disease Diseases 0.000 abstract description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 3
- 239000003094 microcapsule Substances 0.000 abstract description 2
- 229930003779 Vitamin B12 Natural products 0.000 abstract 1
- 229930003756 Vitamin B7 Natural products 0.000 abstract 1
- 230000036737 immune function Effects 0.000 abstract 1
- 235000019163 vitamin B12 Nutrition 0.000 abstract 1
- 239000011715 vitamin B12 Substances 0.000 abstract 1
- 235000011912 vitamin B7 Nutrition 0.000 abstract 1
- 239000011735 vitamin B7 Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 description 25
- 239000000047 product Substances 0.000 description 13
- 239000002245 particle Substances 0.000 description 10
- 241000894006 Bacteria Species 0.000 description 5
- -1 and at 0.08Mpa Substances 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 239000007787 solid Substances 0.000 description 5
- 230000036541 health Effects 0.000 description 4
- 230000007774 longterm Effects 0.000 description 4
- 239000000470 constituent Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000009360 aquaculture Methods 0.000 description 2
- 244000144974 aquaculture Species 0.000 description 2
- 239000005515 coenzyme Substances 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000001363 autoimmune Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 235000012631 food intake Nutrition 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 102000027411 intracellular receptors Human genes 0.000 description 1
- 108091008582 intracellular receptors Proteins 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 208000030159 metabolic disease Diseases 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D7/00—Edible oil or fat compositions containing an aqueous phase, e.g. margarines
- A23D7/01—Other fatty acid esters, e.g. phosphatides
- A23D7/011—Compositions other than spreads
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
- A23D9/007—Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
- A23D9/013—Other fatty acid esters, e.g. phosphatides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/158—Fatty acids; Fats; Products containing oils or fats
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/174—Vitamins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A61K31/51—Thiamines, e.g. vitamin B1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Animal Husbandry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Dispersion Chemistry (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Nutrition Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Description
Time | 1 month | 3 months | 6 months | 12 months | 18 months |
Embodiment 1 | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous |
Embodiment 2 | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous |
Embodiment 3 | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous |
Time | 1 month | 3 months | 6 months | 12 months | 18 months |
Embodiment 4 | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous |
Embodiment 5 | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous | The weak yellow liquid stable homogeneous |
Time | 1 month (%) | 3 months (%) | 6 months (%) | 12 months (%) | 18 months (%) |
Vitamin A | ??99.97 | ??99.95 | ??99.95 | ??99.94 | ??99.93 |
Vitamin D | ??99.94 | ??99.93 | ??99.93 | ??99.91 | ??99.91 |
Vitamin E | ??99.96 | ??99.95 | ??99.93 | ??99.93 | ??99.91 |
Vitamin K | ??99.99 | ??99.97 | ??99.97 | ??99.95 | ??99.95 |
Claims (10)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2010101796369A CN101822320B (en) | 2010-05-22 | 2010-05-22 | Vitamin water aqua and preparation method thereof |
AU2011101750A AU2011101750A4 (en) | 2010-05-22 | 2011-05-20 | Aqueous formulation of vitamins and preparation method thereof |
KR1020127021887A KR20130083822A (en) | 2010-05-22 | 2011-05-20 | Aqueous formulation of vitamins and preparation method thereof |
PCT/CN2011/074437 WO2011147281A1 (en) | 2010-05-22 | 2011-05-20 | Aqueous formulation of vitamins and preparation method thereof |
AU2011257786A AU2011257786A1 (en) | 2010-05-22 | 2011-05-20 | Aqueous formulation of vitamins and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2010101796369A CN101822320B (en) | 2010-05-22 | 2010-05-22 | Vitamin water aqua and preparation method thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101822320A true CN101822320A (en) | 2010-09-08 |
CN101822320B CN101822320B (en) | 2013-07-03 |
Family
ID=42686660
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2010101796369A Active CN101822320B (en) | 2010-05-22 | 2010-05-22 | Vitamin water aqua and preparation method thereof |
Country Status (4)
Country | Link |
---|---|
KR (1) | KR20130083822A (en) |
CN (1) | CN101822320B (en) |
AU (2) | AU2011257786A1 (en) |
WO (1) | WO2011147281A1 (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011147281A1 (en) * | 2010-05-22 | 2011-12-01 | 鼎正动物药业(天津)有限公司 | Aqueous formulation of vitamins and preparation method thereof |
CN102552058A (en) * | 2011-12-27 | 2012-07-11 | 东南大学 | Compound vitamin lipid nanoparticle and preparation method thereof |
CN103783323A (en) * | 2014-02-05 | 2014-05-14 | 褚旭 | Method for preparing compound vitamin premix for animals |
CN104000833A (en) * | 2014-03-07 | 2014-08-27 | 江西赣南海欣药业股份有限公司 | Vitamin D2 and calcium levulinate injection composition and preparation method thereof |
CN108208411A (en) * | 2018-03-01 | 2018-06-29 | 山东德州神牛药业有限公司 | A kind of livestock and poultry metabolism immunological regulation composite solution and preparation method thereof |
CN110339169A (en) * | 2018-09-06 | 2019-10-18 | 澳汀斯(广州)生物医药科技有限公司 | Coat nano vesicle preparations and its application of vitamin D and vitamin K |
CN114766674A (en) * | 2022-04-26 | 2022-07-22 | 湖南赛菱思生物科技有限公司 | Microcapsule powder compounded with MCT and phospholipid oil as well as preparation method and application thereof |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103549219B (en) * | 2013-11-19 | 2015-03-04 | 厦门星鲨动物保健品厂 | Drug feed additive for promoting skin health of aquatic animals and preparation method thereof |
KR20160008275A (en) * | 2014-07-14 | 2016-01-22 | 배대승 | Vitamin C Composition with Improved Absorption Rate and the Method thereof (1) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1096194A (en) * | 1993-06-07 | 1994-12-14 | 北京和德实业公司 | The cosmetics of the lecithin liposome of embedding vitamin and method for making thereof |
CN1225815A (en) * | 1998-06-10 | 1999-08-18 | 南方医院 | Dried lipid article and preparation method therefor |
CN1364459A (en) * | 2001-07-02 | 2002-08-21 | 刘银良 | Method for preparing slow-releasing and controlled releasing functional microcapsule |
CN1410055A (en) * | 2002-06-06 | 2003-04-16 | 上海家化联合股份有限公司 | Vitamin A liposome and its preparation method |
CN101502326A (en) * | 2009-02-23 | 2009-08-12 | 江南大学 | Method for preparing vitamin E nano liposome |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6361800B1 (en) * | 2000-04-13 | 2002-03-26 | Cooper Concepts, Inc. | Multi-vitamin and mineral supplement |
CN1843327A (en) * | 2006-04-17 | 2006-10-11 | 重庆医药工业研究院有限责任公司 | Stable freeze-dried formulation containing multiple kinds of vitamin and its preparation method |
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CN101822320B (en) * | 2010-05-22 | 2013-07-03 | 鼎正动物药业(天津)有限公司 | Vitamin water aqua and preparation method thereof |
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WO2011147281A1 (en) * | 2010-05-22 | 2011-12-01 | 鼎正动物药业(天津)有限公司 | Aqueous formulation of vitamins and preparation method thereof |
CN102552058A (en) * | 2011-12-27 | 2012-07-11 | 东南大学 | Compound vitamin lipid nanoparticle and preparation method thereof |
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CN110339169A (en) * | 2018-09-06 | 2019-10-18 | 澳汀斯(广州)生物医药科技有限公司 | Coat nano vesicle preparations and its application of vitamin D and vitamin K |
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Also Published As
Publication number | Publication date |
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AU2011101750A4 (en) | 2015-02-05 |
WO2011147281A1 (en) | 2011-12-01 |
AU2011257786A1 (en) | 2012-08-30 |
KR20130083822A (en) | 2013-07-23 |
CN101822320B (en) | 2013-07-03 |
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