CN101821281A - 糖蛋白和糖基化的细胞以及其制备方法 - Google Patents

糖蛋白和糖基化的细胞以及其制备方法 Download PDF

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Publication number
CN101821281A
CN101821281A CN200880110687A CN200880110687A CN101821281A CN 101821281 A CN101821281 A CN 101821281A CN 200880110687 A CN200880110687 A CN 200880110687A CN 200880110687 A CN200880110687 A CN 200880110687A CN 101821281 A CN101821281 A CN 101821281A
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CN
China
Prior art keywords
sugar
cells
peptide
peptide conjugate
sugar moieties
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN200880110687A
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English (en)
Chinese (zh)
Inventor
G·戴卡尼
K·阿戈什顿
I·鲍伊佐
M·博伊斯特拉普
L·克勒格尔
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Glycom AS
Original Assignee
Glycom AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycom AS filed Critical Glycom AS
Publication of CN101821281A publication Critical patent/CN101821281A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN200880110687A 2007-09-25 2008-09-24 糖蛋白和糖基化的细胞以及其制备方法 Pending CN101821281A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200701381 2007-09-25
DKPA200701381 2007-09-25
PCT/EP2008/062728 WO2009040363A1 (en) 2007-09-25 2008-09-24 Glycoproteins and glycosylated cells and a method for the preparation of the same

Publications (1)

Publication Number Publication Date
CN101821281A true CN101821281A (zh) 2010-09-01

Family

ID=40089962

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880110687A Pending CN101821281A (zh) 2007-09-25 2008-09-24 糖蛋白和糖基化的细胞以及其制备方法

Country Status (7)

Country Link
US (1) US8785594B2 (https=)
EP (1) EP2190857A1 (https=)
JP (1) JP2010540488A (https=)
CN (1) CN101821281A (https=)
AU (1) AU2008303584C1 (https=)
CA (1) CA2700587A1 (https=)
WO (1) WO2009040363A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9816122B2 (en) 2012-09-25 2017-11-14 Glycom A/S Glycoconjugate synthesis
JP6289177B2 (ja) * 2014-03-11 2018-03-07 国立大学法人 東京大学 含窒素複素環化合物の製造方法
EP4477741A3 (en) 2014-06-27 2025-03-05 Glycom A/S Oligosaccharide production
EP4179102A1 (en) 2020-07-13 2023-05-17 Glycom A/S Oligosaccharide production
US20260021172A1 (en) 2022-04-28 2026-01-22 Carbocalyx Gmbh Personalized Anticancer Vaccine Comprising Glycoengineered Tumour Cells or Tumour Cell Fragments
KR20260049791A (ko) * 2023-08-08 2026-04-14 카보칼릭스 게엠베하 라이게이션을 위한 환형 카바메이트 화합물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL194729C (nl) 1986-10-13 2003-01-07 Novartis Ag Werkwijze voor de bereiding van peptidealcoholen via vaste fase.
DE4003574A1 (de) 1990-02-07 1991-08-08 Bayer Ag Neue dipeptide, verfahren zu ihrer herstellung und ihre verwendung als renininhibitoren in arzneimitteln

Also Published As

Publication number Publication date
AU2008303584C1 (en) 2013-10-10
EP2190857A1 (en) 2010-06-02
US20100261873A1 (en) 2010-10-14
CA2700587A1 (en) 2009-04-02
JP2010540488A (ja) 2010-12-24
AU2008303584B2 (en) 2013-06-27
US8785594B2 (en) 2014-07-22
AU2008303584A1 (en) 2009-04-02
WO2009040363A1 (en) 2009-04-02

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Application publication date: 20100901