CN101791385B

CN101791385B - Medicine for treating psoriasis

Info

Publication number: CN101791385B
Application number: CN2010101377399A
Authority: CN
Inventors: 程海东
Original assignee: Individual
Current assignee: Individual
Priority date: 2010-04-02
Filing date: 2010-04-02
Publication date: 2011-05-11
Anticipated expiration: 2030-04-02
Also published as: CN101791385A

Abstract

The invention discloses a Chinese medicine for treating psoriasis, and is characterized in that the Chinese medicine is prepared by the following raw materials in parts by weight: 1-2 parts of lightyellow sophora root, 1-2 parts of Phellodendron amurense, 1-2 parts of Radix saposhnikoviae, 1-3 parts of honeysuckle, 1-2 parts of Fructus forsythiae, 1-2 parts of Radix stemonae, 1-2 parts of common cnidium fruit, 1-2 parts of dock root, 1-2 parts of Rhizoma smilacis Glabrae, 1-10 parts of centipede, 1-10 parts of Buthus martensi Karsch, 1-2 parts of Chinese angelica, 1-2 parts of leatherleaf millettia, 1-2 parts of Chinese starjasmine stem, 1-2 parts of long pepper, 1-5 parts of coix seed, 1-2 parts of Rhizoma atractylodis and 1-2 parts of dried tangerine peel. The curative effect of the medicine is obvious, the effect can be obtained within 6-15 days when the medicine is used for treating patients with kinds of psoriasis and the treatment cycle is 3-15 months. Generally, the patients with psoriasis can be cured within 2 weeks to 6 months. The treatment cycle is short, the total expense is low and psoriasis is not apt to relapse after recovery. The obvious effect rate is 100 percent, the cure rate is 92 percent and the relapse rate is only 5 percent.

Description

A kind of antipsoriatics thing

Technical field

The invention belongs to the technical field of Chinese medicine preparation, a kind of specifically antipsoriatics thing.

Background technology

Psoriasis also is psoriasis, belongs to frequently-occurring disease, commonly encountered diseases.Modern medicine has more research to psoriasic pathogeny: pathogenic factor has argumentations such as hereditism, immunology at present.Also relevant for dysfunction, aspect theories such as direct stimulation, trauma infection contamination.Because its cause of disease complexity does not still have final conclusion so far.The traditional Chinese medical science also has various clinical dialectical to psoriasis: reason roughly can be agreed.As heat in blood; Damp and hot gathering blood-deficiency and wind-dry, burning hot flourishing etc.The composite factor of all exopathogen causes that the blood poison accumulates in epidermis, makes the epidermis hyperplasia.Show as the red pimple of needle-like or point-like at first, there is silvery white squama on the surface, and sharpness of border can expand to polylith by several piece.Area also can enlarge.After patient feels pruritus, often strike off surperficial squama, expose scarlet epidermis, and with fragmentary petechial hemorrhage.Because psoriasis is mainly in extremity, scalp, cervical region back.Other internal disease of comparing has influence on normal life of patient and human communication, brings huge mental pressure to patient.For psoriasis, modern medicine adopts aminopterin, ethyliminum, acetic acid morpholine, cyclophosphamide etc. to have Cytotoxic medicine more; Perhaps adopt dexamethasone, the treatment of hormoness such as prednisone.The traditional Chinese medical science also has the medicines that induce sweat such as the QINGKAILING of employing, and polyporusum bellatus improves immunity and in conjunction with ultraviolet light, modes such as steroid hormone or heavy metal coating are used in the part.The weak point of these common drugs is: owing to can not treat targetedly from the multiple variation of patient's inherent mechanism, make curative effect definite inadequately, the medicine that has a psoriasis produce effects to a certain type is to other types DeGrain or absolutely void.Adopt hormone and heavy metal, make that side effect is big during the treatment, the patient can not continue to use, and recurrence appears in drug withdrawal easily, also causes hepatorenal damage easily.Comparatively speaking, Chinese prescription treatment psoriasis has certain advantage compared with Western medicine.The psoriasic prescription of treatment by Chinese herbs is many at present, demonstrates the strength of Chinese medicine culture aspect treatment psoriasis class difficult miscellaneous diseases.

Summary of the invention

In order to solve the problems of the technologies described above, the purpose of this invention is to provide a kind of thoroughly medicine for radical treatment of psoriasis.Technical scheme of the present invention is: a kind of antipsoriatics thing is characterized in that: it is to be made by the raw material of following weight parts: Radix Sophorae Flavescentis 1-2, Cortex Phellodendri 1-2, Radix Saposhnikoviae 1-2, Flos Lonicerae 1-3, Fructus Forsythiae 1-2, Radix Stemonae 1-2, Fructus Cnidii 1-2, Radix Rumicis 1-2, Rhizoma Smilacis Glabrae 1-2, Scolopendra 1-10, Scorpio 1-10, Radix Angelicae Sinensis 1-2, Caulis Spatholobi 1-2, Caulis Trachelospermi 1-2, Fructus Piperis Longi 1-2 SEMEN COICIS 1-5 Rhizoma Atractylodis 1-2 Pericarpium Citri Reticulatae 1-2.

Medicine optimal proportion of the present invention is: Radix Sophorae Flavescentis 2, Cortex Phellodendri 2, Radix Saposhnikoviae 2, Flos Lonicerae 6, Fructus Forsythiae 3, the Radix Stemonae 2, Fructus Cnidii 2, Radix Rumicis 2, Rhizoma Smilacis Glabrae 2, Scolopendra 2, Scorpio 5, Radix Angelicae Sinensis 2, Caulis Spatholobi 2, Caulis Trachelospermi 2, Fructus Piperis Longi 2, SEMEN COICIS 6, Rhizoma Atractylodis 2, Pericarpium Citri Reticulatae 2.

The present invention has had new breakthrough again on the basis of the medication custom of traditional monarch.No longer adopt single monarch drug and ministerial drug, but adopt many monarchs, many ministers, many assistants, the balance compatibility mode that makes more.With Radix Sophorae Flavescentis, Cortex Phellodendri, Radix Saposhnikoviae is monarch drug, gets the cold blood poison of separating of Radix Sophorae Flavescentis Cortex Phellodendri.With Radix Saposhnikoviae, Flos Lonicerae, Fructus Forsythiae is ministerial drug; Radix Saposhnikoviae is protected table, and Flos Lonicerae and Fructus Forsythiae induce sweat and disperse poison in the blood.Get Scolopendra, Scorpio is an adjuvant drug, dispel the wind, detoxifcation, collateral dredging.Radix Stemonae Caulis Spatholobi and other Chinese medicine are messenger drug, and Yin Yang balancing prevents recurrence.Be applicable to the psoriasis that multiple factor causes.

Beneficial effect: compared with prior art, the invention has the advantages that: 1, dose little (being no more than 10g), taking convenience.Taking three every day gets final product; 2, pure drug matching, no hormone and cytotoxic drug do not contain heavy metal class medicine, and side effect is little; 3, cheap, most of Chinese medicine is all very common, is convenient to buy, and the patient easily accepts; 4, determined curative effect, relapse rate is low.Even recurrence is also easily cured after continuing to take.

The present invention can make dosage forms such as powder, syrup, the watered pill, honeyed pill.

Clinical use patient is 300 examples, and the men and women half and half.Contain heat in blood, damp and hotly accumulate the psoriasis symptom that long-pending, blood-deficiency and wind-dry, burning hot multiple factor such as flourishing cause.Calculate the crude drug amount according to the dosage form that is made into, take oral theoretical crude drug amount 5-10g, took continuously 6-15 days, all patients' squama hypertrophy phenomenon alleviates, and squama can come off voluntarily, and it is hemorrhage that needle-like no longer appears in the position that comes off voluntarily.After continuing to take 3-6 month, the overwhelming majority can be fully recovered.

Be the concrete clinical case data of part below, be used for proving curative effect of the present invention.

25 years old Shanxi Province of example 1 king * * woman Fenyang City Yang Jiazhuan town village village consultation time: on March 4th, 2004.Upon somebody's introduction, toss about in bed to see a doctor.Whole body pruritus, extremity body side and the back squama that is silvery white in color comes off, and after squama came off, the surface was scarlet, with petechial hemorrhage.Through being diagnosed as psoriasis, main suit's whole body pruritus desquamation 5 years, no history of past illness, no family history.Take Chinese medicine of the present invention every day 3 times, each 10g takes the back check of 1 week, and focus is obviously dwindled, and pruritus alleviates.After continuing to take two weeks, the focus complete obiteration.2004 so far, follows up a case by regular visits to and do not have recurrence.

Example 2 field * * woman age 24 Fenyang City, three spring Zhenping Lu Cun consultation times: on August 15th, 2007.Upon somebody's introduction, see a doctor simultaneously, surplus main suit's whole body pruritus desquamation ten year, the large tracts of land skin lesion occurs with father.Have a strong impact on social activity and employment.No history of past illness has family history, hereditary history.After making a definite diagnosis psoriasis, take Chinese medicine of the present invention every day 3 times, each 5g takes the back check of 1 week, and the squama edge is general red, and squama presents the sign that comes off.Continue to take the back check of 6 weeks, squama comes off fully; After continuing to take 3 weeks, it is normal that skin lesion recovers.2007 so far, follows up a case by regular visits to and do not have recurrence.

Area just outside a city gate, Fenyang City town, example 3 Song * * man age 40 Shanxi consultation time: on JIUYUE 20th, 2008.See a doctor through ward mate's introduction, be diagnosed as the psoriasis initial stage, health is not seen the large area skin infringement.Scalp and hand psoriasis feature are obvious.Main suit's desquamation phenomenon was near 1 year.Slight drug allergy history is arranged, and no history of past illness does not have hereditary history.Take Chinese medicine of the present invention every day 3 times, each 8g takes the back check of 1 week, and squama can come off voluntarily, and the position that comes off is scarlet, no longer follows needle-like hemorrhage.After continuing to take two weeks, the focus complete obiteration, it is normal that skin recovers.Follow up a case by regular visits to and do not have recurrence.

Use the eurypalynous psoriasis patient of example surplus the clinical treatment 300 of the present invention, 276 patients cure in successively during two weeks to 6 month, and skin recovers normally.14 examples recurrence occurs in the back of recovering, and after continuing to take medicine, all cure in 3 weeks.Take in the oral dose 5-10g scope all effectively, dosage and effective time exist related, and the too small meeting of dosage makes the effective time prolongation.Other antipsoriatics thing of comparing, the present invention is evident in efficacy, for polytype psoriasis patient, gets final product produce effects in 6-15 days, and treatment cycle is 3-15 month.General two weeks to 6 month can cure.Treatment cycle is short, and total cost is low, and more the back is difficult for recurrence.Obvious effective rate 100%, cure rate 92%, relapse rate only is 5%.

The specific embodiment:

Embodiment 1: various medicines of ratio by weight: Radix Sophorae Flavescentis 2, Cortex Phellodendri 2, Radix Saposhnikoviae 2, Flos Lonicerae 3, Fructus Forsythiae 2, the Radix Stemonae 2, Fructus Cnidii 2, Radix Rumicis 2, Rhizoma Smilacis Glabrae 2, Scolopendra 10, Scorpio 10, Radix Angelicae Sinensis 2, Caulis Spatholobi 2, Caulis Trachelospermi 2, Fructus Piperis Longi 2, SEMEN COICIS 5, Rhizoma Atractylodis 2, Pericarpium Citri Reticulatae 2.Temperature is below 100 degrees centigrade, pulverizes after the intensive drying, is screened into 100 order fine powders, fully mixes.Make powder.

Embodiment 2: various medicines of ratio by weight: Radix Sophorae Flavescentis 1, Cortex Phellodendri 1, Radix Saposhnikoviae 1, Flos Lonicerae 1, Fructus Forsythiae 1, the Radix Stemonae 1, Fructus Cnidii 1, Radix Rumicis 1, Rhizoma Smilacis Glabrae 1, Scolopendra 1, Scorpio 1, Radix Angelicae Sinensis 1, Caulis Spatholobi 1, Caulis Trachelospermi 1, Fructus Piperis Longi 1, SEMEN COICIS 1, Rhizoma Atractylodis 1, Pericarpium Citri Reticulatae 1 are got suitable quantity of water, are not advisable to have medicine.Decoct secondary, each 1 hour.Twice decoction liquor is with 100 order silk screen filter, and it is 1.03 that filtrate mixing is concentrated into proportion, and concentrated solution adds an amount of dense syrup, makes weights such as manufactured goods and crude drug, makes syrup.

Embodiment 3: various medicines of ratio by weight: Radix Sophorae Flavescentis 1.5, Cortex Phellodendri 1.5, Radix Saposhnikoviae 1.5, Flos Lonicerae 1.5, Fructus Forsythiae 1.5, the Radix Stemonae 1.5, Fructus Cnidii 1.5, Radix Rumicis 1.5, Rhizoma Smilacis Glabrae 1.5, Scolopendra 5, Scorpio 5, Radix Angelicae Sinensis 1.5, Caulis Spatholobi 1.5, Caulis Trachelospermi 1.5, Fructus Piperis Longi 1.5, SEMEN COICIS 1.5, Rhizoma Atractylodis 1.5, Pericarpium Citri Reticulatae 1.5 processing powders are broken into 100 order fine powders, fully mix.Add entry or honey, general ball is made every the watered pill or honeyed pill that weighs 0.3g.

Claims

1. antipsoriatics thing, it is characterized in that: it is to be made by the raw material of following weight parts: Radix Sophorae Flavescentis 1-2, Cortex Phellodendri 1-2, Radix Saposhnikoviae 1-2, Flos Lonicerae 1-3, Fructus Forsythiae 1-2, Radix Stemonae 1-2, Fructus Cnidii 1-2, Radix Rumicis 1-2, Rhizoma Smilacis Glabrae 1-2, Scolopendra 1-10, Scorpio 1-10, Radix Angelicae Sinensis 1-2, Caulis Spatholobi 1-2, Caulis Trachelospermi 1-2, Fructus Piperis Longi 1-2, SEMEN COICIS 1-5, Rhizoma Atractylodis 1-2, Pericarpium Citri Reticulatae 1-2.

2. a kind of antipsoriatics thing according to claim 1 is characterized in that it is to be made by the raw material of following weight parts: Radix Sophorae Flavescentis 2, Cortex Phellodendri 2, Radix Saposhnikoviae 2, Flos Lonicerae 3, Fructus Forsythiae 2, the Radix Stemonae 2, Fructus Cnidii 2, Radix Rumicis 2, Rhizoma Smilacis Glabrae 2, Scolopendra 2, Scorpio 5, Radix Angelicae Sinensis 2, Caulis Spatholobi 2, Caulis Trachelospermi 2, Fructus Piperis Longi 2, SEMEN COICIS 5, Rhizoma Atractylodis 2, Pericarpium Citri Reticulatae 2.

3. according to claim 1,2 described a kind of antipsoriatics things, it is characterized in that: various Chinese herbal medicine are made syrup, the watered pill, honeyed pill or powder.

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