CN1202845C - Medicine for treating prostatosis and its prepn - Google Patents

Medicine for treating prostatosis and its prepn Download PDF

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Publication number
CN1202845C
CN1202845C CN 02133225 CN02133225A CN1202845C CN 1202845 C CN1202845 C CN 1202845C CN 02133225 CN02133225 CN 02133225 CN 02133225 A CN02133225 A CN 02133225A CN 1202845 C CN1202845 C CN 1202845C
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China
Prior art keywords
radix
medicine
ethanol
add
rhizoma rhei
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Expired - Fee Related
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CN 02133225
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CN1403118A (en
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张弘
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HUINAN CHANGLONG BIOCHEMICAL PHARMACEUTICAL CO Ltd JILIN PROV
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HUINAN CHANGLONG BIOCHEMICAL PHARMACEUTICAL CO Ltd JILIN PROV
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Priority to CN 02133225 priority Critical patent/CN1202845C/en
Publication of CN1403118A publication Critical patent/CN1403118A/en
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Abstract

The present invention relates to a traditional Chinese medicine preparation, namely medicine for treating prostate diseases and a preparation method thereof. The medicine is a tablet preparation which is prepared from rhubarb, Chinese honeylocust abnormal fruit, cassia bark, cattail pollen, talc and medicinal cyathula root by specified proportions. The method comprises that cassia bark and rhubarb are extracted in alcohol, cattail pollen and medicinal cyathula root are extracted in water, and then, alcohol extracting solution and water extracting solution are mixed with Chinese honeylocust abnormal fruit and talc. The present invention has the characteristics of stasis removal, consciousness restoration, urination promotion, obvious curative effect and stable process.

Description

A kind of medicine for the treatment of prostatosis and preparation method thereof
Technical field: the present invention relates to a kind of Chinese medicine preparation, promptly treat the prostatitis laurel xanthate and the preparation method of prostatosis.
Background technology: in prior art, hyperplasia of prostate can belong to " difficulty in urination " category with regard to its clinical manifestation, and the difficulty in urination is meant with urine amount few, drop and going out, very then inaccessible obstructed be a kind of disease of primary symptom.Prostatic hyperplasia is not only painful unusual, and delay is difficult, and even threat to life.In recent years, domestic Western medicine has urine logical, and Phenoxybenzamine, furosemide lead to, and imported medicine has proscar or the like, and Chinese patent medicine has QIANLIEKANG, and the prostatitis is easypro etc., and characteristics are respectively arranged, and finds no the prescription identical with the present invention by retrieval.
Summary of the invention: the objective of the invention is provides a kind of new combination, the prostatitis laurel xanthate and the preparation method of treatment prostatosis evident in efficacy at above-mentioned situation.
Technical solution of the present invention is: a kind of prostatitis laurel xanthate thing for the treatment of prostatosis, and it is made by the raw material of following weight: Radix et Rhizoma Rhei (processed) 4.25-5.75g, Fructus Gleditsiae Abnormalis 4.25-5.75g, Cortex Cinnamomi 6.5-8.5g, Pollen Typhae 8.5-11.5g, Talcum 8.5-11.5g, Radix Cyathulae 8.5-11.5g.Preferred dosage form is a tablet, but is not limited to tablet, and also each medicinal component and pharmaceutical carrier or additive are mixed and made into the medicinal common dosage forms of going up such as capsule, pill, electuary, oral liquid, granule.
The Therapeutic Principle is with eliminating stasis and resolving masses, and is sensible that water is main.Radix Et Rhizoma Rhei has stasis removing in the side, the effect that purging fire and cooling blood, clots absorbing stimulate the menstrual flow, going into blood can blood stasis removing and clots absorbing, the diabetes with polydipsia as the prominent symptom distention and fullness in the abdomen, and more can strengthen the power of blood circulation promoting competent silt and slow down the purgation power of rushing down after the Radix Et Rhizoma Rhei processed with wine, if the resistance of the urethra stasis of blood is for a long time in addition, the suspicion of heat-transformation is then arranged, and the double again energy of Radix et Rhizoma Rhei (processed with wine) Qinghua is damp and hot, thereby brings into play its blood circulation promoting and blood stasis dispelling, current blood vessels, eliminate distension, dredge the stagnant effect of the stasis of blood, and be monarch drug.Minister is got its suffering and is loose to walk to scurry with pig angle soap, consciousness restoring, foul, the clear dirty of this being longer than of medicine, broken stagnant, the logical plug of switching of eliminating stagnation.Cortex Cinnamomi the kidney warming circulation of qi promoting and help the gasification of bladder, a surname's promoting blood circulation makes the QI and blood colleague.Two medicines are assisted monarch drug, and the Xingqi vim and vigour are arranged, the hard intestinal stasis relieving that disappears, and sensible eliminating stagnation helps the merit of functioning of bladder, thereby strengthens the power of eliminating stasis and resolving masses, creates the advantage of getting rid of pathogenic factor.Assistant is with Pollen Typhae, Talcum, and two medicines are real to be grey the loosing of Pu of " Medical Treasures of the Golden Chamber ", has blood stasis dispelling blood, detumescence promoting the circulation of blood, the merit that must urinate.Talcum is had one's ideas straightened out treating stranguria, eliminating dampness and diuresis.Two medicines are associated with, and can help and help monarch-minister drug a surname to stop up intestinal stasis relieving, and sensible diuretic is strengthened and opened the energy of urinary tract stasis of blood resistance.Make with Radix Cyathulae, its property master sedimentation, kind descending.Therefore borrow it to make for drawing, the disease of can going directly institute can increase blood circulation promoting and blood stasis dispelling, broken knot again, loose and stop up swollen power.Six medicines share plays eliminating stasis and resolving masses altogether, the effect of sensible diuretic, and outgrowth body of prostate dwindles gradually, and the resistance of the urinary tract stasis of blood is removed thereupon.
Preparation method: get Fructus Gleditsiae Abnormalis and be ground into coarse powder; In addition Cortex Cinnamomi is added 3 times of amount ethanol, reflux, extract, 1 hour is filtered, and filtrate recycling ethanol is standby; Get Radix Et Rhizoma Rhei again, add 8 times of amount 70% ethanol, reflux, extract, 2 hours is filtered, filtrate recycling ethanol, and being concentrated into relative density is 1.30-1.32 (80 ℃); Get Talcum, add 10 times of amounts of water, decocted 1 hour; The Radix Et Rhizoma Rhei and the Cortex Cinnamomi medicinal residues that add Pollen Typhae, Radix Cyathulae and cross with alcohol reflux decoct twice, add 10 times of amounts of water for the first time, decocted 2 hours, and added 8 times of amounts of water for the second time, decocted 1.5 hours, filter, merge filtrate twice, being concentrated into relative density is 1.30-1.32 (80 ℃); Add Radix Et Rhizoma Rhei ethanol extraction and Fructus Gleditsiae Abnormalis powder, mixing is made bulky grain, in 60-80 ℃ of drying, pulverizes, and sieves, and adds small amount of ethanol and granulates, and drying sprays into the Cortex Cinnamomi ethanol extract, mixes thoroughly, dry, and tabletting, coating, promptly.
Function cures mainly: eliminating stasis and resolving masses, and sensible diuresis is used for the urinary tract stasis-eliminating disease of I, II phase prostatic hyperplasia, and disease is seen frequent micturition, and urgent micturition is compeled, and it is not smooth to urinate, dribble of urine, purplish tongue petechia, hesitant pulse or string.
The consumption usage: with the tablet is example, oral, one time 4 (0.3g), 3 times on the one.
Advantage of the present invention is: 1, the present invention is the compound Chinese medicinal preparation with actual effect, and the treatment prostatic hyperplasia is respond well, do not find toxic and side effects, and the medicine source is extensive, and the medicine valency is cheap, and the patient is easy to accept, especially mostly high weak patients suitable drugs treatment of several years.2, process stabilizing, Rational Parameters, conservation guarantees drug effect.3, the second clinical hospital shows that to 90 routine hyperplasia of prostate patient clinical observations total effective rate 91.67% of the present invention obviously is better than matched group (60%) through the Norman Bethune Medical University.The present invention simultaneously is to the heart, liver, the no abnormal influence of renal function, and bad reflection is slight, takes safe and effective.
Below in conjunction with embodiment the present invention is described in further detail:
The specific embodiment:
Embodiment 1: osmanthus, prostatitis pornographic movie: Radix et Rhizoma Rhei (processed) 5g, Fructus Gleditsiae Abnormalis 5g, Cortex Cinnamomi 7.5g, Pollen Typhae 10g, Talcum 10g, Radix Cyathulae 10g.
Embodiment 2: osmanthus, prostatitis pornographic movie: Radix et Rhizoma Rhei (processed) 5.5g, Fructus Gleditsiae Abnormalis 4.5g, Cortex Cinnamomi 7.0g, Pollen Typhae 11g, Talcum 11g, Radix Cyathulae 11g.
Preparation method: raw material: Radix Et Rhizoma Rhei (processed with wine) 200g, Fructus Gleditsiae Abnormalis 200g, Cortex Cinnamomi 300g, Pollen Typhae 400g, Talcum 400g, Radix Cyathulae 400g makes 1000.
Get Fructus Gleditsiae Abnormalis and be ground into coarse powder; In addition Cortex Cinnamomi is added 3 times of amount ethanol, reflux, extract, 1 hour is filtered, and filtrate recycling ethanol is standby to 100ml; Get Radix Et Rhizoma Rhei again, add 8 times of amount 70% ethanol, reflux, extract, 2 hours is filtered, filtrate recycling ethanol, and being concentrated into relative density is 1.30-1.32 (80 ℃); Get Talcum, add 10 times of amounts of water, decocted 1 hour; The Radix Et Rhizoma Rhei and the Cortex Cinnamomi medicinal residues that add Pollen Typhae, Radix Cyathulae and cross with alcohol reflux decoct twice, add 10 times of amounts of water for the first time, decocted 2 hours, and added 8 times of amounts of water for the second time, decocted 1.5 hours, filter, merge filtrate twice, being concentrated into relative density is 1.30-1.32 (80 ℃); Add Radix Et Rhizoma Rhei ethanol extraction and Fructus Gleditsiae Abnormalis powder, mixing is made bulky grain, in 60-80 ℃ of drying, pulverizes, and crosses 100 mesh sieves, adds a small amount of 68% alcohol granulation, and drying sprays into the Cortex Cinnamomi ethanol extract, mixes thoroughly, dry, and tabletting, coating, promptly.

Claims (5)

1, a kind of medicine for the treatment of prostatosis is characterized in that it is made by the raw material of following weight:
Radix et Rhizoma Rhei (processed) 4.25-5.75g, Fructus Gleditsiae Abnormalis 4.25-5.75g, Cortex Cinnamomi 6.5-8.5g, Pollen Typhae 8.5-11.5g, Talcum 8.5-11.5g, Radix Cyathulae 8.5-11.5g.
2,, it is characterized in that dosage form is a tablet according to the medicine of the described treatment prostatosis of claim 1.
3,, it is characterized in that making by the raw material of following weight according to the medicine of the described treatment prostatosis of claim 2:
Radix et Rhizoma Rhei (processed) 5g, Fructus Gleditsiae Abnormalis 5g, Cortex Cinnamomi 7.5g, Pollen Typhae 10g, Talcum 10g, Radix Cyathulae 10g.
4,, it is characterized in that dosage form is capsule, pill, electuary, oral liquid or granule according to the medicine of the described treatment prostatosis of claim 1.
5, a kind of preparation method of medicine of treatment prostatosis as claimed in claim 2 is characterized in that method for making is as follows:
Get Fructus Gleditsiae Abnormalis and be ground into coarse powder; In addition Cortex Cinnamomi is added 3 times of amount ethanol, reflux, extract, 1 hour is filtered, and filtrate recycling ethanol is standby; Get Radix Et Rhizoma Rhei again, add 8 times of amount 70% ethanol, reflux, extract, 2 hours is filtered, filtrate recycling ethanol, and being concentrated into relative density is 1.30-1.32; Get Talcum, add 10 times of amounts of water, decocted 1 hour; The Radix Et Rhizoma Rhei and the Cortex Cinnamomi medicinal residues that add Pollen Typhae, Radix Cyathulae and cross with alcohol reflux decoct twice, add 10 times of amounts of water for the first time, decoct 2 hours, add 8 times of amounts of water for the second time, decoct 1.5 hours, filter, and merge filtrate twice, and being concentrated into relative density is 1.30-1.32; Add Radix Et Rhizoma Rhei ethanol extraction and Fructus Gleditsiae Abnormalis powder, mixing is made bulky grain, in 60-80 ℃ of drying, pulverizes, and sieves, and adds small amount of ethanol and granulates, and drying sprays into the Cortex Cinnamomi ethanol extract, mixes thoroughly, dries tabletting, coating.
CN 02133225 2002-10-17 2002-10-17 Medicine for treating prostatosis and its prepn Expired - Fee Related CN1202845C (en)

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Application Number Priority Date Filing Date Title
CN 02133225 CN1202845C (en) 2002-10-17 2002-10-17 Medicine for treating prostatosis and its prepn

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Application Number Priority Date Filing Date Title
CN 02133225 CN1202845C (en) 2002-10-17 2002-10-17 Medicine for treating prostatosis and its prepn

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CN1403118A CN1403118A (en) 2003-03-19
CN1202845C true CN1202845C (en) 2005-05-25

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