Background technology
Psoriasis, also known as psoriasis, is a kind of chronic dermatosis of common comparatively suitable recurrent exerbation.The traditional Chinese medical science is thought: primary disease and wind, wet, heat, poison, five aspects of becoming silted up are relevant: think now: its disease may with hereditary, infect, dysbolismus, spiritual hypertonicity, immune factor have relation.This disease is not only common but also obstinate, though not direct life-threatening, patient suffering can't bear.Hinder specious simultaneously, have a strong impact on live and work.
The psoriasic method of current treatment has: therapy of combining Chinese and Western medicine, folk prescription, grass side, boil medicine scald, external-applied ointment, tincture water preparation, not phototherapy, the multiple methods such as therapy of blood-letting and antitumor drug treatment, will developing into of being in a bad way controls with hormone.To be objective, various prescription has certain curative effect, but does not find that certain Drug therapy primary disease effect is fine.What the state of an illness was lighter also has cure rate, and state of an illness pertinacious disease that is long, that do not cure for a long time, serious symptom only has certain curative effect, but relapse rate is high.And life-time service hormone and antitumor drug easily cause anemia, leukemia.Real elimination very few, often makes patient lose treatment information, so that bring ineffable hardship.
Summary of the invention
The object of this invention is to provide one and treat psoriasic Chinese medicine, natural pure, the safety non-toxic of this medicine, does not have dependency.
The preparation method of this medicine is provided to be another goal of the invention of the present invention.
Medicine of the present invention is that crude drug prepares by the Chinese medicine of following parts by weight:
Radix Rehmanniae 10-50 big gun Squama Manis 8-18 Rhizoma Smilacis Glabrae 10-19
Radix Angelicae Sinensis 6-30 Radix Salviae Miltiorrhizae 6-18 Radix Sophorae Flavescentis 10-90
Radix Sophorae Tonkinensis 6-30 Cortex erythrinae 10-25 Cortex Phellodendri 10-20
Cortex Mori 10-60 Fructus Forsythiae 6-60 Caulis Spatholobi 10-18
Radix Scutellariae 10-30 Pericarpium Granati 10-20 Spina Gleditsiae 10-20
Favus skin 10-50 Rhizoma Osmundae 10-60 Cortex Moutan 10-30
Herba Ecliptae 10-30 Rhizoma Zingiberis Recens Cordyceps 10-18 Caulis Polygoni Multiflori 10-50
Radix Glycyrrhizae 10-18.
Said medicine can be made on pharmaceutics that any one dosage form is as tablet, pill, powder, capsule, the present invention is oral liquid preferably.
The concrete preparation method above-mentioned each component being made oral liquid of the present invention is:
By even for the medicament mixed of above-mentioned weight portion, decoct with water 2 ~ 4 times, each 1 ~ 2 hour, collecting decoction, filter, filtrate is condensed into the clear paste of 70 DEG C of relative densities 1.15 ~ 1.18, cold preservation leaves standstill, and gets supernatant and filters, customary adjuvant is added in filtrate, mixing, add purified water to being 1g/ml containing crude drug amount, oral liquid formulations is made in embedding, sterilizing.
Using method: oral, each 1 bag, every bag of 500ml, every day three times.
Psoriasic inducement mostly is Nervous and Mental Factors, due to overworked, and family quarrel, relatives die, economic problems etc. make patient mental's hypertonicity, are in a very depressed state, and can cause a series of psychoreaction, cause endocrine regulation, immunologic function degression, thus facilitate psoriatic generation and development.By differential diagnosis in tcm analysis, what psoriasis had " blood dry, heat in blood, blood deficiency " resembles, and the traditional Chinese medical science is thought, feelings will internal injury, obstruction of QI, strongly fragrant fire-transformation of a specified duration, and scorchingly hot volt to occur in nutrient blood that this is sick.The present invention is special antipsoriatic good recipe, can alleviate and improve by endocrine regulation, the symptom that immunologic function degression causes.Radix Rehmanniae in the present invention, effect that Rhizoma Osmundae has clearing away heat and cooling blood, tonifying YIN promotes the production of body fluid; Big gun Squama Manis can subside a swelling burst carbuncle, search wind active; Rhizoma Smilacis Glabrae removing toxic substances, dehumidifying; Favus skin heat clearing and damp drying, removing toxic substances of dispeling the wind, for damp and hot sore, scabies skin ulcer La.Entirely can share by all medicines above, be used for the treatment of psoriasis cure rate high, without Western medicine preparation to side effect such as human epidermal infringements, the also drug resistance such as antibiotic-free.
For investigating clinical efficacy and the safety of medicine of the present invention further, 14 routine psoriatics are selected to carry out clinical observation to the curative effect of medicine of the present invention.
Criterion of therapeutical effect: according to " new Chinese medicine treats psoriasic guideline of clinical investigations " regulation, efficacy determination based on transference cure, and changes situation with reference to sign etc., is divided into healing, effective, effective, invalid level Four.Cure: symptom and sign all disappear.Effective: symptom and sign are obviously improved.Effective: symptom and sign have certain improvement.Invalid: symptom and sign are all without improvement.
Through Ureteral Calculus, patient is used in conjunction ten days.14 routine patients, cure 8 examples, and take a turn for the better 6 examples, total effective rate 100%.Without any side effect and untoward reaction.
Embodiment:
Get Radix Rehmanniae 30kg, big gun Squama Manis 13kg, Rhizoma Smilacis Glabrae 15kg, Radix Angelicae Sinensis 25kg, Radix Salviae Miltiorrhizae 13kg, Radix Sophorae Flavescentis 70kg, Radix Sophorae Tonkinensis 25kg, Cortex erythrinae 18kg, Cortex Phellodendri 12kg, Cortex Mori 40kg, Fructus Forsythiae 40kg, Caulis Spatholobi 12kg, Radix Scutellariae 20kg, Pericarpium Granati 15kg, Spina Gleditsiae 15kg, favus skin 30kg, Rhizoma Osmundae 30kg, Cortex Moutan 15kg, Herba Ecliptae 15kg, Rhizoma Zingiberis Recens Cordyceps 12kg, Caulis Polygoni Multiflori 30kg, Radix Glycyrrhizae 12kg, clean with clear water, decoct with water 3 times, each 1 ~ 2 hour, collecting decoction, filter, filtrate is condensed into the clear paste of 70 DEG C of relative densities 1.15 ~ 1.18, cold preservation leaves standstill, get supernatant to filter, customary adjuvant is added in filtrate, mixing, adding purified water to containing crude drug amount is 1g/ml, embedding, oral liquid formulations is made in sterilizing.
Case history one: Changzi County surnamed Zhang man, homeliness type psoriasis 18 years, hospitalization western medicines in treatment and external traditional Chinese medicine ointment wiping, do not cure, recurrent exerbation, aggravation always, take Drug therapy of the present invention, continue to take medicine after 3 courses for the treatment of of taking medicine to consolidate and do not recur so far a course for the treatment of.
Case history two: Tunliu County Li female, suffers from psoriasis for many years, and head is serious, and face is rare, spreads all over whole body.Each hospital out-patient treatment, various method was all used, and never treated, and treated with Chinese herb medicine of the present invention, and 2 courses for the treatment of take a turn for the better, and cure, do not recur so far after 3 courses for the treatment of.