CN101782575B - Inner ring and outer ring double flow line structure for fully-automatic immunity analyzer - Google Patents
Inner ring and outer ring double flow line structure for fully-automatic immunity analyzer Download PDFInfo
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- CN101782575B CN101782575B CN 201010111423 CN201010111423A CN101782575B CN 101782575 B CN101782575 B CN 101782575B CN 201010111423 CN201010111423 CN 201010111423 CN 201010111423 A CN201010111423 A CN 201010111423A CN 101782575 B CN101782575 B CN 101782575B
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Abstract
The invention discloses an inner ring and outer ring double flow line structure for a fully-automatic immunity analyzer, comprising an inner ring and an outer ring. The inner ring and the outer ring are both turnplates connected with a power source and are concentrically arranged. The inner ring is in a disc shape, the edge of the inner ring is provided with an inner ring reaction cup trough along the circumference, and the opening direction of the inner ring reaction cup trough is outward. The edge of the outer ring is provided with an outer ring reaction cup trough along the circumference, and the opening direction of the outer ring reaction cup trough is inward. The opening of the inner ring reaction cup trough and the opening of the outer ring reaction cup trough are arranged opposite to each other. The inner ring and outer ring double flow line structure also comprises a reaction cup stand which is adaptive to both the inner ring reaction cup trough and the outer ring reaction cup trough, and the reaction cup stand is connected with a conversion device and is arranged in the inner ring reaction cup trough and/or the outer ring reaction cup trough. The invention provides the inner ring and outer ring double flow line structure which is used for the fully-automatic immunity analyzer, and is matched with the fully-automatic immunity analyzer so as to realize random sample introduction, random detection and convenient operation, reduces the waste and reduces the use cost.
Description
Technical field
The present invention relates to a kind of device that is used for clinical immune diagnostic technique, especially a kind of inner ring and outer ring double flow line structure that is used for automatic lmunoassays analyzer.
Background technology
At present, clinical immune diagnostic technique is one of main auxiliary diagnosis technology that is widely used in domestic and international each medical institutions, has important role for the detection and the treatment of clinical disease.The core of clinical immune diagnostic technique is the specific reaction of antigen and antibody, according to the difference of observation signal, is divided into multiple diagnostic techniquess such as enzyme linked immunological, radio-immunity, colloid gold immune, fluorescence immunoassay and chemiluminescence immunoassay again; Difference according to carrier is divided into homogeneous phase and solid phase etc. again.Because cost; The difference of environment and properties of product; The most extensive with enzyme linked immunological and two kinds of technical application of chemiluminescence at present; Wherein board-like chemiluminescence detection reagent is accepted rapidly by the home market because of it is more suitable for China's actual conditions, increases just with surprising rapidity based on board-like chemiluminescence detection reagent market at home at present.
Board-like immune diagnostic reagent has easy and simple to handle, advantage such as cost is low, "dead" pollution, result are accurate with respect to other immune diagnostic reagent, and clinical at home at present immunodiagnosis market has occupied than great share.But there is a bigger defective in board-like immune diagnostic reagent; Promptly can't realize sample introduction at random, with the function of machine testing, thereby in clinical use small-middle hospital especially, when sample size less; And under the more situation of emergency treatment sample; Can make user's operation inconvenience, also cause waste significantly simultaneously, increase user's use cost.
Summary of the invention
The purpose of this invention is to provide a kind of be used for automatic lmunoassays analyzer and can cooperate with automatic lmunoassays analyzer realize at random sample introduction, with machine testing, easy to operate, cut the waste, thereby reduce the inner ring and outer ring double flow line structure of use cost.
For realizing above-mentioned purpose; The present invention adopts following technical scheme: a kind of inner ring and outer ring double flow line structure that is used for automatic lmunoassays analyzer, and ring and outer shroud in comprising, inner and outer rings is the rotating disk that is connected with power source and both are concentric is provided with; And interior ring is discoid; Ring reaction cup groove in interior ring edge is provided with along the border, interior ring reaction cup channel opening direction is outside, and outer shroud offers outer shroud reaction cup groove along the border; Outer shroud reaction cup channel opening direction is inside, and interior ring reaction cup channel opening and outer shroud reaction cup channel opening are provided with in opposite directions; Comprise also and interior ring reaction cup groove and all suitable reaction saucer of outer shroud reaction cup groove that the reaction saucer is connected with conversion equipment, encircle in reaction cup groove and/or the outer shroud reaction cup groove in the reaction saucer is arranged at.
Said conversion equipment comprises the conversion motor, and reaction saucer center is provided with the conversion motor output shaft is eccentric, and the reaction saucer removably connects with the conversion motor output shaft.
Outer shroud is the disk of diameter greater than interior ring diameter, and interior ring is arranged at the outer shroud upper surface, and said outer shroud reaction cup groove is provided with along the border, edge at outer shroud upper surface upside, and interior ring reaction cup channel opening is oppositely arranged with outer shroud reaction cup channel opening and bottom land flushes.
Said reaction saucer is a semicolumn; Be provided with the reaction saucer in the inner and outer rings reaction cup groove respectively, react saucer down; Last reaction saucer semi arch faces sunken inside, and following reaction saucer semi arch faces outer the depression, when last reaction saucer and two vertical planes that react saucer down are relative fully; The one side angle point place of last reaction saucer upper surface is provided with the transposition hole, and the opposite side angle point place of the following reaction saucer relative with last transposition hole is provided with down the transposition hole; The output axle head of said conversion motor drives a transpositing plate, respectively establishes a transpositing pin on the transpositing plate of output axle head both sides, and when two vertical planes of last reaction saucer and reaction saucer down fully relatively the time, upper and lower two transpositing pin positions are corresponding with upper and lower transposition hole site respectively.
Outer shroud is driven through belt driver by the outer shroud motor, and interior ring is driven through a pair of transmission gear by interior ring motor.
In ring top be installed with cover in the incubation disk center fixed head of ring and outer shroud, encircle the reaction cup groove in the incubation disk center fixed head edge correspondence and relative outer shroud reaction cup groove is provided with at least 4 breach.
Said conversion motor, interior ring motor and outer shroud motor are stepper motor.
The ring stepper motor is arranged at the upper surface of incubation disk center fixed head in said; And incubation disk center fixed head is provided with the reaction cup pick-up unit, the reaction cup pick-up unit through control circuit with change motor and/or interior ring motor and/or outer shroud motor signal and be connected.
Reaction cup backing face is provided with the locating convex block of two halves spherical shape, and all corresponding two locating convex blocks of bottom land of interior ring reaction cup groove and outer shroud reaction cup groove are respectively equipped with two halves spherical shape detent.
The trench bottom of outer shroud reaction cup groove is provided with the reaction cup through hole, and the corresponding reaction cup through hole of reaction saucer also is provided with through hole.
Beneficial effect of the present invention is: adopt the design of inner and outer rings separate type; Control the rotation of inner and outer rings respectively through the inner and outer rings stepper motor; Can distinguish independent adjustment inner and outer rings sense of rotation and speed like this; Reaction cup is loaded on the reaction saucer, and in ring or the outer shroud reaction cup groove, interior ring or outer shroud are sent to appointed positions according to instruction with reaction cup in the reaction cup holder being placed on again.The reaction saucer that carries through interior ring or outer shroud is sent to assigned address with reaction cup.Reaction cup is accomplished washing, substrate respectively, detects and adds the course of work of reaction cup, sample, reactant along with the rotation of interior ring and outer shroud.The inner and outer ring transfer device can freely be changed the reaction saucer that interior ring and outer shroud carry between inner and outer ring according to instruction; Thereby raising detection efficiency; The reaction cup that automatic lmunoassays analyzer can be at any time detected needs carried out various operations, has realized at random sample introduction, with machine testing, and is easy to operate; Cut the waste, thereby reduced use cost.Conversion equipment is when work; Two transpositing pins insert two transposition holes of upper and lower reaction saucer respectively; The rotation of conversion driven by motor transpositing plate so two transpositing pins also perhaps turn clockwise counterclockwise, changes over upper and lower reaction saucer rotation; Last reaction saucer falls in the outer shroud reaction cup groove, encircles in the reaction cup groove in following reaction saucer falls into.Incubation disk center fixed head can play the effect of protection inner structure; 4 breach of incubation disk center fixed head will expose corresponding several to inner and outer rings reaction saucer, and the inner and outer rings reaction saucer in 4 breach can be respectively applied for to be played cup, add reagent or lose cup, detect or add substrate, wash cup.The reaction cup pick-up unit is position transducer or optical sensor or temperature sensor or pressure transducer; Can detect the saucer that responds that whether drops in the inner and outer rings reaction cup bracket, and then send signal instruction with perhaps interior ring motor of conversion motor or outer shroud motor.Two locating convex blocks of reaction cup backing face and two detents can hold up the effect of location to reaction cup, simultaneously, when conversion equipment need be to the pop-jump change place of reaction cup, exert oneself slightly, and the reaction saucer can rotate.The through hole of reaction cup through hole and reaction saucer helps when not needing reaction cup, reaction cup to be hit down.
Description of drawings
Fig. 1 is a structural representation of the present invention;
Fig. 2 is the A-A view shown in Fig. 1;
Fig. 3 is the structural representation of inner and outer rings and conversion equipment;
Fig. 4 is the structural representation of conversion equipment;
Fig. 5 is the left view of Fig. 4;
Fig. 6 is the structural representation of interior ring reaction cup groove and outer shroud reaction cup groove;
Fig. 7 is the structural representation of reaction saucer.
Embodiment
By Fig. 1-a kind of inner ring and outer ring double flow line structure that is used for automatic lmunoassays analyzer shown in Figure 7, be horizontally disposed with interior ring transmission gear 3, interior ring 28, upper end cover 7, outer shroud 8, belt driver 10 and the bottom end cover 11 of incubation disk center fixed head 2, pair of meshing from top to bottom successively.Interior ring 28 is discoid rotating disk with outer shroud 8; The diameter of outer shroud 8 is greater than interior ring 28 diameters; In ring 28 be arranged at outer shroud 8 upper surfaces, interior ring 28 and outer shroud 8 all are arranged on the same vertical stationary shaft 12 and both are provided with one heart, interior ring 28 edges are provided with ring reaction cup groove 9 in the semicircular arc along the border; The semicircular arc opening direction of interior ring reaction cup groove 9 is outside; Outer shroud 8 upper surface upsides are provided with semicircular arc outer shroud reaction cup groove 14 along the border, edge, the semicircular arc opening direction of outer shroud reaction cup groove 14 is inside, and interior ring reaction cup groove 9 openings are oppositely arranged with outer shroud reaction cup groove 14 openings and bottom land flushes.Inner and outer rings reaction cup groove 9,14 is provided with 30 respectively; Also comprise the semi-cylindrical reaction saucer 18 that is connected and vertically is provided with conversion equipment 20; Reaction saucer 18 shapes and interior ring reaction cup groove 9 are all suitable with outer shroud reaction cup groove 14; In the inner and outer rings reaction cup groove 9,14 respectively correspondence be provided with reaction saucer 16, react saucer 15 down, reaction saucer 18 can be provided with totally 60.Last reaction saucer 16 semi arches face sunken inside, and following reaction saucer 15 semi arches face outer depression.Said conversion equipment 20 comprises housing 25 and the housing 25 interior conversion motors 21 that are provided with; The output axle head of conversion motor 21 drives a transpositing plate 23 through a pair of transposition transmission gear that is meshed 22; Respectively establish a transpositing pin 24 on the transpositing plate 23 of output axle head both sides; When last reaction saucer 16 and two vertical planes that react saucer 15 down are relative fully; The one side angle point place of last reaction saucer 16 upper surfaces is provided with transposition hole 17, and the opposite side angle point place of the following reaction saucer 15 relative with last transposition hole 17 is provided with down the hole 17 of replacing; When half-terete two vertical planes of going up reaction saucer 16 and reaction saucer 15 down fully relatively the time, upper and lower two transpositing pins 24 positions are corresponding with 17 positions, upper and lower transposition hole respectively.Outer shroud is driven through belt driver 10 by outer shroud motor 1; And the driven pulley 13 of belt driver 10 is fixedly arranged on the downside of outer shroud 8 lower surfaces; Interior ring 28 encircles transmission gear 3 drives by interior ring motor 4 in one pair; And the upside of ring 28 upper surfaces in the follower gear 6 of interior ring transmission gear 3 is fixedly arranged on, said incubation disk center fixed head 2 is the plate-likes of ring 28 in covering and outer shroud 8, stationary shaft 12 tops of ring top in incubation disk center fixed head 2 is fixedly arranged on.Ring reaction cup groove 9 and relative outer shroud reaction cup groove 14 thereof are provided with 4 breach A, B, C, D in the incubation disk center fixed head 2 edge correspondences.Ring motor 4 is arranged at the upper surface of incubation disk center fixed head 2 in said; And incubation disk center fixed head 2 upper surfaces also are provided with reaction cup pick-up unit 26; Reaction cup pick-up unit 26 is position transducer or optical sensor or temperature sensor or pressure transducer; Reaction cup pick-up unit 26 is connected (said control circuit is a prior art, so be not described in detail) through control circuit with conversion motor 21 and/or interior ring motor 4 and/or outer shroud motor 1 signal.Said conversion motor 21, interior ring motor 4 and outer shroud motor 1 are stepper motor.Reaction saucer 18 bottom surfaces are provided with the locating convex block 30 of two halves spherical shape, and all corresponding two locating convex blocks 30 of bottom land of interior ring reaction cup groove 9 and outer shroud reaction cup groove 14 are respectively equipped with two halves spherical shape detent 27.The trench bottom of outer shroud reaction cup groove 14 is provided with reaction cup through hole 19, and the corresponding reaction cup through hole 19 of reaction saucer also is provided with through hole 32.Said stationary shaft 12 and inner and outer rings 28, between 8, between the engaged wheel 13 of stationary shaft 12 and belting, stationary shaft 12 is provided with bearing 5 respectively with the follower gear 6 of interior ring transmission gear 3.
During work; Inner and outer ring rotates respectively; 4 breach A of incubation disk center fixed head 2, B, C, D will expose corresponding several can being respectively applied for the inner and outer rings reaction saucer 16,15 in 16,15,4 breach of inner and outer rings reaction saucer and play cup, add reagent or lose cup, detect or add substrate, wash cup.Conversion equipment 20 is when work; Two transpositing pins 24 insert two transposition holes 17 of upper and lower reaction saucer 15 respectively; Conversion motor 21 drives transpositing plate 23 rotations, so two transpositing pins 24 also perhaps turn clockwise counterclockwise, upper and lower reaction saucer 15 rotations is changed over; Last reaction saucer 16 falls in the outer shroud reaction cup groove 14; Under react saucer 15 fall in the ring reaction cup groove 9, so, when reaction saucer 18 is arranged in outer shroud reaction cup groove 14, become reaction saucer 15 down; When reaction saucer 18 is arranged in ring reaction cup groove 9, become and go up reaction saucer 16; The setting of replace the up and down hole 17 and the transpositing pin 24 of upper and lower reaction saucer 15,16 is actually through reacting the saucer center and change the eccentric setting of motor 21 output shafts, reacting saucer and change motor 21 output shafts and removably connects, and upper and lower reaction saucer 16, the 15 rotation realizations of conversion motor 21 drives replace.Incubation disk center fixed head 2 also can play the effect of protection inner structure; The reaction cup pick-up unit is position transducer or optical sensor or temperature sensor or pressure transducer; Can detect the saucer that responds that whether drops in the inner and outer rings reaction cup bracket, and then send signal instruction with perhaps interior ring motor 4 of conversion motor 21 or outer shroud motor 1.Two locating convex blocks 30 of reaction cup backing face and two detents 27 can hold up the effect of location to reaction cup, simultaneously, when conversion equipment 20 need be to the pop-jump change place of reaction cup, exert oneself slightly, and the reaction saucer can rotate.The through hole 31 of reaction cup through hole 19 and reaction saucer helps when not needing reaction cup, reaction cup to be hit down.Certainly, the present invention is not limited to above-mentioned form, also can in the reaction cup bracket of interior ring 28 or outer shroud 8, reaction cup be set as required as required, and reaction saucer 18 encircles in reaction cup groove 9 or the outer shroud reaction cup groove 14 in also can setting up and placing.
Claims (8)
1. inner ring and outer ring double flow line structure that is used for automatic lmunoassays analyzer is characterized in that: ring and outer shroud in comprising, inner and outer rings are the rotating disk that is connected with power source and both are concentric is provided with; And interior ring is discoid; Ring reaction cup groove in interior ring edge is provided with along the border, interior ring reaction cup channel opening direction is outside, and outer shroud offers outer shroud reaction cup groove along the border; Outer shroud reaction cup channel opening direction is inside, and interior ring reaction cup channel opening and outer shroud reaction cup channel opening are provided with in opposite directions; Comprise also and interior ring reaction cup groove and all suitable reaction saucer of outer shroud reaction cup groove that the reaction saucer is connected with conversion equipment, encircle in reaction cup groove and/or the outer shroud reaction cup groove in the reaction saucer is arranged at; Said conversion equipment comprises the conversion motor, and reaction saucer center is provided with the conversion motor output shaft is eccentric, and the reaction saucer removably connects with the conversion motor output shaft; Said reaction saucer is a semicolumn; Be provided with the reaction saucer in the inner and outer rings reaction cup groove respectively, react saucer down; Last reaction saucer semi arch faces sunken inside, and following reaction saucer semi arch faces outer the depression, when last reaction saucer and two vertical planes that react saucer down are relative fully; The one side angle point place of last reaction saucer upper surface is provided with the transposition hole, and the opposite side angle point place of the following reaction saucer relative with last transposition hole is provided with down the transposition hole; The output axle head of said conversion motor drives a transpositing plate, respectively establishes a transpositing pin on the transpositing plate of output axle head both sides, and when two vertical planes of last reaction saucer and reaction saucer down fully relatively the time, upper and lower two transpositing pin positions are corresponding with upper and lower transposition hole site respectively.
2. the inner ring and outer ring double flow line structure that is used for automatic lmunoassays analyzer as claimed in claim 1; It is characterized in that: outer shroud is the disk of diameter greater than interior ring diameter; Interior ring is arranged at the outer shroud upper surface; Said outer shroud reaction cup groove is provided with along the border, edge at outer shroud upper surface upside, and interior ring reaction cup channel opening is oppositely arranged with outer shroud reaction cup channel opening and bottom land flushes.
3. the inner ring and outer ring double flow line structure that is used for automatic lmunoassays analyzer as claimed in claim 2 is characterized in that: outer shroud is driven through belt driver by the outer shroud motor, and interior ring is driven through a pair of transmission gear by interior ring motor.
4. the inner ring and outer ring double flow line structure that is used for automatic lmunoassays analyzer as claimed in claim 3; It is characterized in that: the incubation disk center fixed head of ring and outer shroud in interior ring top is installed with and covers, ring reaction cup groove and relative outer shroud reaction cup groove thereof are provided with at least 4 breach in the incubation disk center fixed head edge correspondence.
5. the inner ring and outer ring double flow line structure that is used for automatic lmunoassays analyzer as claimed in claim 4 is characterized in that: said conversion motor, interior ring motor and outer shroud motor are stepper motor.
6. the inner ring and outer ring double flow line structure that is used for automatic lmunoassays analyzer as claimed in claim 5; It is characterized in that: the ring stepper motor is arranged at the upper surface of incubation disk center fixed head in said; And incubation disk center fixed head is provided with the reaction cup pick-up unit, the reaction cup pick-up unit through control circuit with change motor and/or interior ring motor and/or outer shroud motor signal and be connected.
7. the inner ring and outer ring double flow line structure that is used for automatic lmunoassays analyzer as claimed in claim 6; It is characterized in that: reaction cup backing face is provided with the locating convex block of two halves spherical shape, and all corresponding two locating convex blocks of bottom land of interior ring reaction cup groove and outer shroud reaction cup groove are respectively equipped with two halves spherical shape detent.
8. the inner ring and outer ring double flow line structure that is used for automatic lmunoassays analyzer as claimed in claim 7 is characterized in that: the trench bottom of outer shroud reaction cup groove is provided with the reaction cup through hole, and the corresponding reaction cup through hole of reaction saucer also is provided with through hole.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010111423 CN101782575B (en) | 2010-02-10 | 2010-02-10 | Inner ring and outer ring double flow line structure for fully-automatic immunity analyzer |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 201010111423 CN101782575B (en) | 2010-02-10 | 2010-02-10 | Inner ring and outer ring double flow line structure for fully-automatic immunity analyzer |
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| CN101782575A CN101782575A (en) | 2010-07-21 |
| CN101782575B true CN101782575B (en) | 2012-12-05 |
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Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104330550B (en) * | 2013-04-03 | 2017-05-10 | 艾博生物医药(杭州)有限公司 | Apparatus and method for identifying front and back directions of detection board |
| CN104237127B (en) * | 2014-09-12 | 2017-03-15 | 苏州国科鼎翼生物科技有限公司 | Specimen holder and corresponding analyzer with TIP head placement mechanisms |
| CN105301227B (en) * | 2015-11-04 | 2017-03-29 | 徐恩良 | A kind of any project team's parallel reaction processing meanss of immune detection |
| CN109917145B (en) * | 2017-12-12 | 2023-06-20 | 深圳拓真生物科技有限公司 | Full-automatic chemiluminescence immunoassay instrument |
| CN109230449B (en) * | 2018-08-22 | 2024-03-12 | 威海威高生物科技有限公司 | Steering sample rack |
| CN113834798A (en) * | 2021-07-28 | 2021-12-24 | 北京茂泽科技有限公司 | Multifunctional optical detection and analysis system |
| CN115541907B (en) * | 2022-10-09 | 2023-10-03 | 深圳市国赛生物技术有限公司 | Full-automatic chemiluminescence immunoassay instrument |
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| CN1963527B (en) * | 2005-11-10 | 2011-12-14 | 深圳迈瑞生物医疗电子股份有限公司 | Full-automatic biochemical analyzer and analysis method thereof |
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| EP0100663A2 (en) * | 1982-07-30 | 1984-02-15 | Corning Glass Works | Dilution cups for spectrophotometer analyzer |
| EP1102068A1 (en) * | 1999-11-16 | 2001-05-23 | Maxmat SA | Biochemical analyzer with means for identification of tubes |
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| CN101782575A (en) | 2010-07-21 |
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Application publication date: 20100721 Assignee: Nanjing bosai Biotechnology Co.,Ltd. Assignor: Zhengzhou Biocell Biotechnology Co.,Ltd. Contract record no.: 2014320000662 Denomination of invention: Inner ring and outer ring double flow line structure for fully-automatic immunity analyzer Granted publication date: 20121205 License type: Exclusive License Record date: 20140903 |
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Address after: 450016 No. 28, First Avenue, Zhengzhou economic and Technological Development Zone, Henan Patentee after: ZHENGZHOU RENFU BIOCELL BIOTECHNOLOGY Co.,Ltd. Address before: 450016 No. 28, First Avenue, Zhengzhou economic and Technological Development Zone, Henan Patentee before: Zhengzhou Biocell Biotechnology Co.,Ltd. |
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Address after: 450016 No. 28, First Avenue, Zhengzhou economic and Technological Development Zone, Henan Patentee after: Zhengzhou Biocell Biotechnology Co.,Ltd. Address before: 450016 No. 28, First Avenue, Zhengzhou economic and Technological Development Zone, Henan Patentee before: Zhengzhou Bosai Biotechnology Co.,Ltd. Address after: 450016 No. 28, First Avenue, Zhengzhou economic and Technological Development Zone, Henan Patentee after: Zhengzhou Bosai Biotechnology Co.,Ltd. Address before: 450016 No. 28, First Avenue, Zhengzhou economic and Technological Development Zone, Henan Patentee before: ZHENGZHOU RENFU BIOCELL BIOTECHNOLOGY Co.,Ltd. |