CN101779601A - Rat/mouse labyrinth automatic training device - Google Patents

Rat/mouse labyrinth automatic training device Download PDF

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Publication number
CN101779601A
CN101779601A CN 201010121891 CN201010121891A CN101779601A CN 101779601 A CN101779601 A CN 101779601A CN 201010121891 CN201010121891 CN 201010121891 CN 201010121891 A CN201010121891 A CN 201010121891A CN 101779601 A CN101779601 A CN 101779601A
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door
power supply
program control
labyrinth
rat
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彭吉云
李葆明
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Fudan University
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Fudan University
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Abstract

The invention discloses a rat/mouse labyrinth automatic training device, belonging to the technical field of animal behaviors and neuroelectrophysiology experiments. The device comprises a main labyrinth body, an infrared detector, a program control door system which is opened downwards vertically, a PCI (programmable communication interface) interface data acquisition card and a computer control program. A core technology lies in the effective implementation of the program control door system. The device realizes automatic rat/mouse labyrinth training and enables the electrophysiological record of animals carrying out labyrinth task operations to be possible. The program control door has concise structure and stable and reliable work, and the design of opening downwards vertically avoids the blocking and the winding of connecting lines during wired electrophysiological recording; and the invention maintains the conciseness and the smoothness of an original labyrinth to a maximum extent.

Description

Greatly/rat/mouse labyrinth automatic training device
Technical field
The invention belongs to Animal Behavior Science and neural electrophysiology experiment field, be specifically related to a kind of big/rat/mouse labyrinth trainer of automation.
Background technology
Multiple labyrinth model (as the Y/T labyrinth, cross labyrinth, eight arm labyrinths) is the basic means of research rodent learning and memory.Also commonly used in some other field, as identifying cognitive drug screening etc. to carry out cognitive function through the genetic manipulation animal.
In the past when animal being carried out the training of this class labyrinth, the methods that adopt artificial training more.For example rat Y labyrinth delays alternately that task is the most frequently used model of test rat working memory ability.When task was trained, the experimenter need hand a baffle plate and earlier rat was limited in the initiation region in the past, removed baffle plate then behind the lag phase of regulation, allowed animal freely select to enter the passage left side or the right and rewarded to obtain food.Afterwards, the experimenter must grab back animal initiation region continuation experiment.This method requires the experimenter to have higher experiment skill excessively stress to avoid as far as possible animal caused.Obviously, this objectivity that experimenter's requirement has been influenced to a great extent experimental result.
In addition, along with the continuous progress of methods such as behavior electrophysiology, simple behaviouristics is observed the demand that can not satisfy the researcher.When to being in that animal in the task operating carries out that electric physiology is observed and during record, animal artificially being contacted and will cause great interference to observation.The automation of behavior training and programme-controlled be inevitable requirement when free moving animals is carried out electrophysiological recording.
Up to now, do not find the open report identical with technical solution of the present invention.
Summary of the invention
The objective of the invention is on basis, traditional labyrinth, install additional program control door and multiple spot infrared detection device, software and hardware combining, the automation of realization behavior training.
Core of the present invention is effective realization of program control door.Program control door of the present invention adopts opening ways vertically downward, has ensured the succinctly unobstructed of labyrinth channel.When all doors all behind the complete opening, labyrinth channel and original traditional labyrinth channel are almost without any difference, have avoided installing additional a barrier factors that may cause.This point is particularly important when carrying out wired electrophysiological recording.
Provided by the invention big/rat/mouse labyrinth automatic training device, be based on traditional labyrinth trainer, set up program control in each passway in original labyrinth, and some infrared probes be set in each passage, be used for detecting the position of mouse in the labyrinth; In program control door both sides a pair of infrared detection head is set also, whether open and close puts in place to detect program control door; The open and close of program control door is controlled by control circuit.
Among the present invention, the structure of program control door as shown in Figure 2.Program control door is fixed on the labyrinth channel inwall by the chute of both sides, adopts opening ways vertically downward, and promptly program control door can be done vertically to move up and down along the both sides chute, implements opening and closing.The one side top (or below) of program control door and the below (or top) of opposite side have breach, and these two breach are corresponding with program control two infrared probes outdoors respectively; The opening and closing of program control door realize by a two-way d.c. motor and a pull rope.The bottom center of program control door is provided with a small branch plate, is used for positioning towed rope, and an end of pull rope is fixed in the rotating disk that a two-way d.c. motor drives, the medium position place of motor and rotating disk setting and program control door; The chute bottom is close to program control door place and is provided with a plate washer, and smooth and easy to guarantee that program control door moves up and down along chute, the pull rope other end passes small branch plate (not being dead) back and binds with a little metal weight.
Among the present invention, the control circuit of program control door is seen shown in Figure 4.
Among the present invention, list is seen shown in Figure 3 to the circuit diagram of infrared probe.The transmitting terminal Ie1 positive pole of infrared probe connects power supply+5V end, meets the ground terminal G of power supply behind the negative pole series connection protective resistance R1.The receiving terminal Ir1 positive pole of infrared probe connects power supply+5V end, and negative pole is told two lines, connects the ground terminal of power supply behind line serial resistance R2, meets the base stage b of triode T1 after the resistance R 3 of a line series connection.The colelctor electrode c of triode tells two lines, connect after the resistance R 4 of line series connection power supply+the 5V end, output inserts data collecting card to another line as signal.The colelctor electrode of triode T1 connects the ground terminal of power supply.Ultrared transmitting terminal and receiving terminal are coaxial line and install.
Among the present invention, the control circuit of program control door as shown in Figure 4.Wherein, the control circuit that the first half is closed for door, the latter half is a door control of turning circuit.The closed portion circuit of door, the input port CIn of circuit are accepted computer commands output.CIn connects the base stage of triode T2 after the resistance R 5 of series connection.The negative pole end input (No. 8 mouths) of the collector connecting relay J1 of T2, the positive terminal input (No. 1 mouth) of J1 connect power supply+12V end.The emitter stage of T2 is told two lines, and a line connects the ground terminal of power supply after the resistance R 6 of series connection.Article one, connect the emitter stage of auxiliary circuit part triode T3.Relay under non-started state, its pin 2 and 3 short circuits, 6 and 7 short circuits; The input end grounding of motor M, another input is told three lines, No. 4 mouths, No. 2 mouths through relay J 1 connect power supply+the 12V end; Article one, through No. 4 mouths of relay J 2, No. 2 mouths connect power supply-the 12V end; Also have a part to succeed No. 7 mouths of electrical equipment J2 as auxiliary circuit.The auxiliary circuit of closed portion is subjected to the modulation of infrared rays (among Fig. 4 Ie2, Ir2 probe to) on off operating mode.Ie2 is identical with Ie1, connects the power supply of 5V behind the series resistance R10.The positive terminal of Ir2 then connects power supply+12V end, and negative pole end is also identical with Ie1, divides resistance R 8 that two lines connect respectively afterwards to connect the base stage of triode T3 behind ground connection and the connecting resistance R7.The colelctor electrode of triode T3 directly connects power supply+12V end, the emitter stage of T3 is told two lines, and the emitter stage short circuit with T2 is succeeded No. 7 mouths of electrical equipment J1 behind another series connection adjustable resistance R9, succeed No. 6 mouths of electrical equipment J2 again through No. 6 mouths of J1, connect the input of motor again through No. 7 mouths of J2.The circuit of door opening section and the circuit symmetrical of closed portion of door, just relay J 2 controls is-power supply of 12V.
Description of drawings
Fig. 1 is a Y type labyrinth diagram.Wherein: (A) labyrinth top view; (B) labyrinth bottom view.
Fig. 2 is program control door diagram.Wherein: (A) anterior view of program control door; (B) normal cross-section during program control door half propradation; (C) the side section during program control door half propradation.
Fig. 3 is that the right circuit of infrared probe connects.
Fig. 4 is program control gate control circuit.
Number in the figure: 1, infrared probe, 2, program control door, 3, motor, 4, backing support, 5, the pillar installing port, 6, reward point of release, 7, baffle plate, 8, the wiring rotating disk, 9, pull rope, 10, metal drops, 11, cushioning fender, 12, conduit wall, 13, the tether plate, J1, J2 are two eight pin relays, and M is a motor.
Embodiment
Embodiments of the present invention (is example with rat Y labyrinth):
This automation labyrinth device is by the labyrinth main body, Infrared Detectors and control circuit, and program control door pci interface data collecting card and computer-controlled program are formed.
(1) the labyrinth main body is shown in accompanying drawing 1 (A), and the labyrinth main body is " Y " type labyrinth that 3 passages link to each other, and is made up of the selection arm (long 42cm) of an initial arm (long 70cm) and two symmetries.Labyrinth interchannel angle in twos is all identical, is 120 °.Each channel width is identical, and the conduit wall height is also identical, is respectively 14cm and 20cm.For the intensity that can provide program control to open the required installing space of required space and corresponding power set 3 motors downwards and guarantee labyrinth structure in the bottom surface, labyrinth, shown in accompanying drawing 1 (B), the bottom surface, labyrinth is sticked on the A-frame 4 made of iron, and this support is installed on the vertical pillars 5 that the gravity chassis arranged.So, whole labyrinth is in a firm vacant state.
(2) Infrared Detectors accompanying drawing 1 (A) has also identified each infrared probe to 1 installation site.(7 pairs of infrared probes once are labeled as I1 to infrared probe by 7 pairs of diverse locations in the passage, I2......I7), can monitor rat residing position in the labyrinth in real time, thereby can make corresponding reaction by control program according to the rule of setting.For example, open in good time or close certain fan door, award (being the drinking-water of 50~100 μ l in this example) in good time.Each fan door both sides of passage bottom also are equipped with a pair of infrared probe respectively.As the part of program control door subsystem, its circuit diagram is seen accompanying drawing 4.
(3) Infrared Detectors operation principle Fig. 3 is single circuit diagram to infrared probe I1~I7.The transmitting terminal Ie1 positive pole of infrared probe connects power supply+5V end, and negative pole is connected and met the ground terminal G of power supply behind the protective resistance R1 of 100 Ω.Like this, when electric power starting, the transmitting terminal of infrared probe is in the infrared rays emission state always.The receiving terminal Ir1 positive pole of infrared probe connects power supply+5V end, and negative pole is told two lines, connects the ground terminal of power supply after line polyphone 10K Ω resistance R 2, meets the base stage b of triode T1 after the resistance R 3 of a line series connection 1K Ω.The colelctor electrode c of triode T1 tells two lines, connect after the resistance R 4 of line series connection 2K Ω power supply+the 5V end, output inserts data collecting card to a line as signal.The colelctor electrode of triode connects the ground terminal of power supply.Ultrared transmitting terminal and receiving terminal are coaxial line and install, like this two the probe between without hindrance every in, receiving terminal is in low resistive state (less than 1K Ω) by infrared radiation, make through the T1 amplification through the electric current of Ir1 and R2 to be low resistive state between triode c, e, thereby output end voltage approaches 0.When the infrared rays between two probes is blocked by barrier (for example mouse health), receiving terminal loses infrared radiation and is high-impedance state (greater than 1M Ω), be high-impedance state between corresponding triode c, e, a little less than the electric current that passes through is atomic, thereby output end voltage approaches power supply+5V.By gathering the saltus step data of output end voltage, can judge very easily whether mouse is between the current infrared probe.
(4) to be installed in the program control door 2 of the downward unlatching in three passages respectively be the key device of control rat operating process to installation three fans of program control door, the program control door of three fans be numbered I, II, III.Accompanying drawing 1 is seen in each installation site.For other forms of labyrinth, can as required door be installed in the correct position of labyrinth channel equally.The specification of three fan doors is in full accord in this example.Shown in accompanying drawing 2 (A), this door is a wide 13.5cm, the hawk of high 25cm.On the limit, top side of door and the bottom side of offside a small gap (particular location is seen accompanying drawing) that 1.5cm is square is arranged respectively, so, whether two pairs of infrared probes 1 installing in relevant position, bottom surface, labyrinth can provide this information of putting in place of ON/OFF.The bottom center of door has a small branch plate 13, installs to make things convenient for pull rope 9.Shown in accompanying drawing 2 (B), (C), the opening and close of door by lying in due to putting of a pull rope of bottom center position 9 draw.This pull rope other end is fixed in the rotating disk 8 that is driven by bidirectional, dc motor 3.The installation site of motor and rotating disk slightly lateral deviation, is avoided the side direction pulling force to cause the inclination of door and is strengthened friction so that pull rope is in vertical direction in the central authorities of door, cooperates chute and is installed on the bottom surface and presses close to the baffle plate 7 of door-plate, and it is smooth and easy to have guaranteed that door is advanced up and down.Pull rope passes and is not a small branch plate at the bottom of dying from, is tied to a little metal weight 10 after passing again.So, when carrying on the pull rope, can rise together by the moving door of weight ligament; When pull rope is transferred, pull rope is weighed down the thing tractive also will be in tensioned state always, and near the unordered entanglement that may form rotating disk after having avoided rope lax causes operation exception.The unlatching of door is after the pull rope pulling force removes, the result of door self gravitation effect.More reliable for failing after a unlatching is put in place (realizing) by circuit, fall the baffle plate 11 that a band sea buffering is equipped with at the place, position the student.
(5) circuit shown in the program control door principle accompanying drawing 4 closing and open is to be used to realize rationally closing and opening of program control door.The infrared probe at I, II, III door place is designated as I8 and I9 respectively, I10 and I11, I12 and I13.Be the example explanation now with door I.The closed portion of door, the input port CIn of circuit are accepted computer commands output.CIn connects the base stage of triode T2 after the resistance R 5 of series connection 1K Ω.The negative pole end input (No. 8 mouths) of the collector connecting relay of T2 (minimum operating voltage is about 5V) J1, the positive terminal input (No. 1 mouth) of J1 connect power supply+12V end.The emitter stage of T2 is told two lines, and a line connects the ground terminal of power supply after the resistance R 6 of 100 Ω that connect.Article one, connect the emitter stage of auxiliary circuit part triode T3.Relay under non-started state, its pin 2 and 3 short circuits, pin 6 and 7 short circuits; Relay under starting state, its pin 2 and 3 disconnect and with short pin 4 short circuits, short pin 7 disconnect with 6 and with weak point pin 5 short circuits.Such relay essence is a double-point double-throw switch.With the input end grounding of motor M, another input is told three lines, No. 4 mouth, No. 2 mouths through relay J 1 connect power supply+the 12V end; Article one, through No. 4 mouths of relay J 2, No. 2 mouths connect power supply-the 12V end; Also have a part to succeed No. 7 mouths of electrical equipment J2 as auxiliary circuit.The auxiliary circuit of closed portion is subjected to the modulation of infrared rays I8 (among Fig. 4 Ie2, Ir2 probe to) on off operating mode.Ie2 is identical with Ie1, connects the power supply of 5V after the 100 Ω resistance R 10 of connecting.The positive terminal of Ir2 then connects power supply+12V end, and negative pole end is also identical with Ie1, divides the base stage that meets triode T3 after two lines resistance R 8 back ground connection that meet 10K Ω respectively and the resistance R 7 that meets 1K Ω.The colelctor electrode of triode T3 directly connects power supply+12V end, the emitter stage of T3 is told two lines, and the emitter stage short circuit with T2 is succeeded No. 7 mouths of electrical equipment J1 behind another series connection adjustable resistance R9, succeed No. 6 mouths of electrical equipment J2 again through No. 6 mouths of J1, connect the input of motor again through No. 7 mouths of J2.
When door was in complete opening or semi-open state, I8 was in the state of interrupting, and the c utmost point and the e interpolar of triode T3 are high-impedance state.If give the Transistor-Transistor Logic level (this moment, OIn must be in 0 level) of CIn+5V this moment, the b utmost point forward input of T2 makes the c utmost point of T2 and e interpolar be low resistive state, + 12V voltage major part is carried on relay J 1 and the resistance R 6, the voltage that is distributed in this moment on the J1 is enough to allow J1 start, thereby make No. 2 mouths and No. 4 mouth short circuits of J1, begin behind the motor loading+12V voltage to rotate, hoist pull rope, drive door and rise by rotating disk.Close when door and to put in place, when the breach of door bottom side arrived the labyrinth basal surface position, infrared rays I8 connected.Ir2 was in low resistive state and made the b utmost point of triode T3 that bigger input be arranged this moment, so just made the c utmost point of T3 and e interpolar be in low resistive state.Because the c of T3 extremely directly connects power supply+12V end, and e utmost point ground connection again after series resistance, this just make the e utmost point of T3 be at this moment higher current potential (approaching+12V).The e utmost point of T3 and the e utmost point of T2 are short circuits, this potential difference that just means T2 b utmost point this moment and e interpolar is less than 0, and the input of the b utmost point of T2 is invalid, the current blocking between the c utmost point and the e utmost point, relay J 1 is closed condition and makes the disconnection that is connected of No. 2 mouths and No. 4 mouths, original+12V power supply that motor loses.But this moment J1 pin 6 and No. 7 mouth short circuits, the pin 6 of J2 and No. 7 mouths also are short circuits.The e electrode potential of T3 just has been carried on the series circuit of resistance R 9 and motor simultaneously like this, motor is under the effect of powering a little less than this forward and certain positive torque power is arranged, but being not enough to drive door continues to rise, door stops the back also will face bigger resistance if will descend, like this, door just can stop in good time and don't can glide again.The CIn end can remain on before open command is assigned+5V.
The circuit of door opening section and door closed portion be symmetry almost completely, and just relay J 2 controls is-power supply of 12V.Before the door open command was assigned, the shutdown command end of door must be in 0 level state.The startup of relay J 2 is powered a little less than with the forward of motor and is switched to-the 12V power supply, the motor counter-rotating, and pull rope loosens, and door drops naturally with rope.When the student dropped to, the below buffer board stoped door to continue to descend on the one hand, and infrared rays I9 connects on the one hand, and the power supply of motor automatically switches into the weak power supply of forward, pull rope is tightened up once more, but be not enough to door pull-up once more.The pull rope that tightens up makes that also door can in time rise when shutdown command arrival next time, thereby guarantees that each is closed required time basically identical.
(6) circuit protecting element: because the saltus step of relay both sides may be not exclusively synchronous, thereby may cause instantaneous-12V voltage to be loaded on the e end of each triode through R9/R15, make each e end be the negative potential state.In this state, be equivalent to all load forward voltage to CIn and OIn, like this relay will form the vibration and entire circuit can't operate as normal.We draw the negative pole end that a line meets a diode D1 at No. 7 mouths of relay J 1 so, and with the plus earth of D1.Like this, when-when 12V voltage has been loaded into No. 7 mouths of J1 once more, will by directly with guiding to the end.Because this time compole short, be unlikely to cause short circuit to destroy.In addition and since the same terminals of motor will+12V and-switch between 12V, cause short circuit for avoiding fault or program command mistake, we are equipped with fuse F1, F2 at two power supply access ports.
The concrete operations step is as follows:
Delaying to replace task with rat is example, and we write down the neuron discharge in rat specific brain regions district during the rat task operating.The specific tasks flow process is as follows:
1, before task begins, by control program program control door is reset to the I door and close the state that II, III door are opened.After labyrinth state and each parameter condition setting are good, program is changed to " RUN " state.
2, debugged the electrophysiological recording system after, the headstage that will be connected with lead inserts the connector on the rat head, and rat is put into initial arm terminal location.
3, when rats underwent proceeds to the infrared position of I2, program is sent I door open command (+5V Transistor-Transistor Logic level), and pull rope is loosened in revolution, and the I door begins free-falling.When the door complete opening, the cushioning fender under stops door to continue to descend on the one hand, and the input current of motor is reverse on the one hand, and this moment, the opposing torque of motor tightened up pull rope once more, but was not enough to the door pull-up upwards.Like this, door is held open state always.
4, after number door was opened, the time point that rat moves ahead through the infrared position of I3 was recorded, and is used for the off-line data analysis.
5, rat continues to move ahead, and this moment, rat can freely select to enter left channel or right channel.Entering left channel with rat is example, when rat is interrupted the I4 infrared rays, judges that promptly rat has entered the left side.This moment, program was sent the shutdown command of III door, the revolution of III door, and the twist pull rope is pulled upwardly door.When the door rising put in place, the 12V power supply of motor was cut off automatically and is powered a little less than transferring in the same way.Motor had certain positive torque power but was not enough to drive door and continues to rise this moment, and door stops the back and also will face bigger resistance if will descend, so, and door stop motion and the closed condition of sd so always.
When 6, rat continued to proceed to I5 infrared rays position, program was sent the award release command, rewarded to rat drinking-water.
7, after rat finished off water, rat must get back to initial arm and begin task next time.When rat got back to I2 infrared rays place, the II door was closed.When rat continued to proceed to I1 infrared rays place, the I door was closed.Begin to calculate down the time delay that subtask begins this moment.The I door began to close back 1 second, and II, III door are opened simultaneously.
8, postpone (setting for example 5 seconds according to requirement of experiment) through the regular hour, and rat is when being in the infrared position of I2, the I door is opened once more.
9, this moment, rat still can freely enter left side or right channel, but had only when rat enters the passage opposite with last time, and rat can obtain to reward.With last time identical, after judging that rat has made a choice, promptly close the opposite side passage.
10, after rat was made correct selection and obtains to reward or do wrong, rat must get back to initial arm and begin task next time once more, and then selects to enter opposite passage to obtain award next time.Replace and so forth.
Below promptly be that classical rat delays the alternately implementation procedure of task in the Y labyrinth of automation.There is not experimenter's participation in the task process.Omnidistance neuron activity record can reflect verily that rat at the brain activity state in each stage of task, provides reliable data for we further illustrate neural coding mechanism.

Claims (4)

1. one kind big/rat/mouse labyrinth automatic training device, it is characterized in that this trainer is based on traditional labyrinth trainer, set up program control door in each passway in original labyrinth, and some infrared probes are set in each passage, be used for detecting the position of mouse in the labyrinth; In each program control door both sides a pair of infrared detection head is set also, whether open and close puts in place to detect program control door; The open and close of program control door is controlled by control circuit.
2. according to claim 1 big/rat/mouse labyrinth automatic training device, it is characterized in that the chute of described program control door, be fixed on the labyrinth channel inwall, adopt opening ways vertically downward by both sides, be that program control door can be done vertically to move up and down along the both sides chute, implement opening and closing; The one side top of program control door and the below of opposite side have breach, and these two breach are corresponding with program control two infrared probes outdoors respectively; The opening and closing of program control door realize by a two-way d.c. motor and a pull rope: the bottom center of program control door is provided with a small branch plate, be used for positioning towed rope, one end of pull rope is fixed in the rotating disk that the bidirectional, dc motor drives, the medium position place of motor and rotating disk setting and program control door, the pull rope other end binds with a little metal weight after passing small branch plate.
3. according to claim 2 big/rat/mouse labyrinth automatic training device, it is characterized in that described control circuit is divided into a control circuit and a door control of turning circuit that door is closed; The control circuit of closing of door, the input port CIn of circuit are accepted computer commands output; Input port CIn connects the base stage of triode T2 after the resistance R 5 of series connection; The negative pole end input of the collector connecting relay J1 of triode T2, the positive terminal input of relay J 1 connect power supply+12V end; The emitter stage of triode (T2) is told two lines, and a line connects the ground terminal of power supply after the resistance R 6 of series connection; Article one, connect the emitter stage of auxiliary circuit part triode T3; The input end grounding of motor M, another input is told three lines, No. 4 mouth, No. 2 mouths through relay J 1 connect power supply+the 12V end; Article one, through No. 4 mouths of relay J 2, No. 2 mouths connect power supply-the 12V end; Also have a part to succeed No. 7 mouths of electrical equipment J2 as auxiliary circuit; The auxiliary circuit of closed portion is modulated by the infrared rays on off operating mode; Ie2 is identical with Ie1, connects the power supply of 5V behind the series resistance R10; The positive terminal of Ir2 then connects power supply+12V end, and negative pole end is also identical with Ie1, divides resistance R 8 that two lines connect respectively afterwards to connect the base stage of triode T3 behind ground connection and the connecting resistance R7; The colelctor electrode of triode T3 directly connects power supply+12V end, the emitter stage of T3 is told two lines, and the emitter stage short circuit with T2 is succeeded No. 7 mouths of electrical equipment J1 behind another series connection adjustable resistance R9, succeed No. 6 mouths of electrical equipment J2 again through No. 6 mouths of J1, connect the input of motor again through No. 7 mouths of J2; The circuit of door opening section and the circuit symmetrical of closed portion of door, relay J 2 controls be-power supply of 12V.
4. according to claim 2 big/rat/mouse labyrinth automatic training device, it is characterized in that the circuit of described infrared probe team is as follows:
The transmitting terminal Ie1 positive pole of infrared probe connects power supply+5V end, meets the ground terminal G of power supply behind the protective resistance R1 of negative pole series connection; Like this, when electric power starting, the transmitting terminal of infrared probe is in the infrared rays emission state always; The receiving terminal Ir1 positive pole of infrared probe connects power supply+5V end, and negative pole is told two lines, connects the ground terminal of power supply behind line serial resistance R2, meets the base stage b of triode T1 after the resistance R 3 of a line series connection; The colelctor electrode c of triode T1 tells two lines, connect after the resistance R 4 of line series connection power supply+the 5V end, output inserts data collecting card to a line as signal; The colelctor electrode of triode connects the ground terminal of power supply; Ultrared transmitting terminal and receiving terminal are coaxial line and install.
CN 201010121891 2010-03-11 2010-03-11 Rat/mouse labyrinth automatic training device Pending CN101779601A (en)

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WO2020182107A1 (en) * 2019-03-12 2020-09-17 中国科学院脑科学与智能技术卓越创新中心 Spatial working memory behavior training device and training method
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CN113016654A (en) * 2021-03-25 2021-06-25 复旦大学 Visual information-oriented spatial memory behavior training method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3516389A (en) * 1968-02-12 1970-06-23 Arthur Brackett Meyer Experimental modular animal maze
CN1817325A (en) * 2006-02-21 2006-08-16 沈阳医学院 Mouse hearing and vision memory model and intelligent action inspecting system
CN2836461Y (en) * 2005-11-23 2006-11-15 中国科学院心理研究所 Water maze for behavior test of animal study ability

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3516389A (en) * 1968-02-12 1970-06-23 Arthur Brackett Meyer Experimental modular animal maze
CN2836461Y (en) * 2005-11-23 2006-11-15 中国科学院心理研究所 Water maze for behavior test of animal study ability
CN1817325A (en) * 2006-02-21 2006-08-16 沈阳医学院 Mouse hearing and vision memory model and intelligent action inspecting system

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
《北京生物医学工程》 20010930 赵崇侃 《一种用于行为医学的新型红外检测器》 192-193 1-4 第20卷, 第3期 2 *

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012119323A1 (en) * 2011-03-07 2012-09-13 沈阳医学院 Automatic mechanical arm stimulating device for animal memory training system
CN102265792A (en) * 2011-05-16 2011-12-07 浙江中医药大学 Microcomputer-controlled automatic animal dietary behavior detection device
CN102830609A (en) * 2012-08-03 2012-12-19 深圳先进技术研究院 Positioning and timing device and method of animal behavioristics labyrinth
CN102830609B (en) * 2012-08-03 2014-10-29 深圳先进技术研究院 Positioning and timing device and method of animal behavioristics labyrinth
CN103583397A (en) * 2013-11-01 2014-02-19 中国科学院深圳先进技术研究院 Photostimulation device of decision behaviors
CN103583397B (en) * 2013-11-01 2015-09-30 中国科学院深圳先进技术研究院 The light stimulation device of decision behavior
CN105230520A (en) * 2015-07-25 2016-01-13 南昌航空大学 Full-automatic rat maze behavior training system
CN105467107A (en) * 2015-12-15 2016-04-06 中国科学院深圳先进技术研究院 Analysis system
CN109275590A (en) * 2017-07-19 2019-01-29 长沙市公安局刑事侦查支队 A kind of instruction dog device
CN109392755A (en) * 2018-09-29 2019-03-01 中国科学院深圳先进技术研究院 Detect the method and system of scientific research animal behavior
WO2020182107A1 (en) * 2019-03-12 2020-09-17 中国科学院脑科学与智能技术卓越创新中心 Spatial working memory behavior training device and training method
CN111685049A (en) * 2019-03-12 2020-09-22 中国科学院脑科学与智能技术卓越创新中心 Space working memory behavior training device and training method
CN111685049B (en) * 2019-03-12 2022-01-21 中国科学院脑科学与智能技术卓越创新中心 Method for space working memory behavior training
CN109874696A (en) * 2019-04-04 2019-06-14 北京理工大学 A kind of training of animal behavior, test macro and its training method, test method
CN109874696B (en) * 2019-04-04 2024-04-19 北京理工大学 Animal behavior training and testing system and training method and testing method thereof
WO2021078865A1 (en) * 2019-10-22 2021-04-29 Université D'aix Marseille (Amu) Apparatus and system for testing rodents' cognitive ability
CN113016654A (en) * 2021-03-25 2021-06-25 复旦大学 Visual information-oriented spatial memory behavior training method
CN113016654B (en) * 2021-03-25 2021-12-10 复旦大学 Visual information-oriented spatial memory behavior training method

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