CN101773499A - 延胡索乙素的新用途 - Google Patents

延胡索乙素的新用途 Download PDF

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Publication number
CN101773499A
CN101773499A CN200910076383A CN200910076383A CN101773499A CN 101773499 A CN101773499 A CN 101773499A CN 200910076383 A CN200910076383 A CN 200910076383A CN 200910076383 A CN200910076383 A CN 200910076383A CN 101773499 A CN101773499 A CN 101773499A
Authority
CN
China
Prior art keywords
cancer
cell
carcinoma
tetrahydropalmatine
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN200910076383A
Other languages
English (en)
Chinese (zh)
Inventor
张虹
金雪
向俊锋
李骞
谭莉
唐亚林
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Chemistry CAS
Original Assignee
Institute of Chemistry CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute of Chemistry CAS filed Critical Institute of Chemistry CAS
Priority to CN200910076383A priority Critical patent/CN101773499A/zh
Priority to PCT/CN2009/000563 priority patent/WO2010081266A1/fr
Publication of CN101773499A publication Critical patent/CN101773499A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN200910076383A 2009-01-14 2009-01-14 延胡索乙素的新用途 Pending CN101773499A (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN200910076383A CN101773499A (zh) 2009-01-14 2009-01-14 延胡索乙素的新用途
PCT/CN2009/000563 WO2010081266A1 (fr) 2009-01-14 2009-05-22 Utilisation nouvelle de la tétrahydropalmatine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN200910076383A CN101773499A (zh) 2009-01-14 2009-01-14 延胡索乙素的新用途

Publications (1)

Publication Number Publication Date
CN101773499A true CN101773499A (zh) 2010-07-14

Family

ID=42339387

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200910076383A Pending CN101773499A (zh) 2009-01-14 2009-01-14 延胡索乙素的新用途

Country Status (2)

Country Link
CN (1) CN101773499A (fr)
WO (1) WO2010081266A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104327068A (zh) * 2014-09-17 2015-02-04 深圳福山生物科技有限公司 一种用于抗癌镇痛的含硒化合物及其制备方法和用途
CN104490877A (zh) * 2014-12-10 2015-04-08 中国科学院化学研究所 左旋延胡索乙素衍生物的新用途
WO2017080313A1 (fr) * 2015-11-13 2017-05-18 Institute Of Chemistry, Chinese Academy Of Sciences Dérivé de tétrahydropalmatine, son procédé de préparation et utilisation

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020139999A1 (fr) * 2018-12-28 2020-07-02 Addanki Pratap Kumar Traitement du cancer du pancréas
CN112755045B (zh) * 2021-02-04 2022-08-26 新疆医科大学 芜菁中性多糖在制备肺癌a549细胞调控的药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101327214B (zh) * 2008-07-18 2011-01-12 中国药科大学 异喹啉生物碱类作为组织因子抑制剂的医药用途

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104327068A (zh) * 2014-09-17 2015-02-04 深圳福山生物科技有限公司 一种用于抗癌镇痛的含硒化合物及其制备方法和用途
CN104490877A (zh) * 2014-12-10 2015-04-08 中国科学院化学研究所 左旋延胡索乙素衍生物的新用途
WO2017080313A1 (fr) * 2015-11-13 2017-05-18 Institute Of Chemistry, Chinese Academy Of Sciences Dérivé de tétrahydropalmatine, son procédé de préparation et utilisation

Also Published As

Publication number Publication date
WO2010081266A1 (fr) 2010-07-22

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Open date: 20100714