CN101745026A - Setting bone and promoting blood flow plaster for treating fractures and injuries and preparation method thereof - Google Patents

Setting bone and promoting blood flow plaster for treating fractures and injuries and preparation method thereof Download PDF

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CN101745026A
CN101745026A CN201010102478A CN201010102478A CN101745026A CN 101745026 A CN101745026 A CN 101745026A CN 201010102478 A CN201010102478 A CN 201010102478A CN 201010102478 A CN201010102478 A CN 201010102478A CN 101745026 A CN101745026 A CN 101745026A
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promoting blood
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CN101745026B (en
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姜济业
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Abstract

The invention discloses a setting a bone and promoting blood flow plaster for treating fractures and injuries, which is prepared by the following raw materials by a certain weight proportion: angelica, native copper, drachonis sanguis, frankincense and myrrh. The setting a bone and promoting blood flow plaster has the functions of activating blood, bruise trimming, dispersing pathogenic wind, tendon relaxing and reunion of bone, treats traumatic injuries, and has fast treating effect of tendon breaking and fracture and high recovery rate.

Description

A kind of setting bone and promoting blood flow plaster for the treatment of fracture and injury and preparation method thereof
Technical field:
The present invention relates to a kind of medicine for the treatment of fracture and injury and preparation method thereof, belong to the field of Chinese medicines.
Background technology:
Fracture and injury be meant owing to wound the pathology reason causes sclerotin to be partially damaged or fully the fracture a kind of disease.Its main clinical manifestation is: fractures has limitation pain and tenderness, local swelling and ecchymosis occurs, and limb function is limited or completely lose, and the completeness sclerotin still cacomelia and abnormal movement can occur.Acupuncture is mainly used in closed fracture.There is very rich experience in China aspect the treatment fracture.The method of this disease of treatment has western medical treatment and Chinese traditional treatment at present.Western medical treatment is general adopt reset, methods such as external fixation or continuous traction.And traditional Chinese medical science traditional treatment is based on pain relieving, promoting blood circulation to remove blood stasis, though effective in cure, to produce effects slowly, patient suffering's time is long.
Summary of the invention:
Therefore, there are needs greatly in the setting bone and promoting blood flow plaster that people better treat fracture to curative effect, up to now, also do not find any relevant report about setting bone and promoting blood flow plaster of the present invention, the inventor is through research repeatedly, and the checking repeatedly by animal and clinical trial, has finished the present invention finally.
The purpose of this invention is to provide a kind of blood circulation promoting and blood stasis dispelling that has, reducing swelling and alleviating pain, reunion of bone tissue regeneration promoting and the reparation of promotion focus, the setting bone and promoting blood flow plaster that cure rate is high is to be adapted to the miscellaneous fracture dislocation, soft tissue injury, hematoma, comminuted fracture and closed shape fracture.
Another object of the present invention has just provided the preparation method of this setting bone and promoting blood flow plaster.
Medicament selection Radix Angelicae Sinensis of the present invention, Pyritum, Sanguis Draxonis, Olibanum, Myrrha, Eupolyphaga Seu Steleophaga, Flos Carthami, Cortex Cinnamomi, Herba speranskiae tuberculatae, Flos Caryophylli, Moschus, Borneolum Syntheticum, Mentholum, vegetable oil, Plumbum preparatium, Radix Asparagi, Rhizoma Corydalis Decumbentis make up.Make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat fracture and injury.Selecting Radix Angelicae Sinensis is owing to the sweet suffering of its nature and flavor, temperature.Go into the heart, liver, spleen channel.Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving is moisturized laxation.Control menoxenia, amenorrhea stomachache, the lump in the abdomen knot is poly-, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; The dryness of the intestine dyschezia is heavy after the bloody dysentery; The carbuncle skin ulcer is stolen, injury from falling down.Select for use Pyritum to be because its nature and flavor are arduous, flat.Go into kidney meridian, liver channel of foot-Jueyin.Eliminating stasis to stop pain, reunion of bone.Control traumatic injury, the tendon breaking fracture, blood stasis pain is gathered, goiter, skin infection is scalded.Select for use Sanguis Draxonis to be because its property sweet-salty is flat.Go into the heart, Liver Channel.The dissipating blood stasis analgesic therapy, hemostasia and promoting granulation.Control traumatic injury and lose, ecchymoma due to internal injury, continuous bleeding due to traumatic injury, scrofula, ecthyma unhealed for long time.Select for use Olibanum to be because its nature and flavor are arduous, warm.Go into the heart, liver, spleen channel.Regulating qi and activating blood, analgesic therapy chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.Select for use Myrrha to be because its nature and flavor hardship is flat.Go into Liver Channel.Diffusing blood blood stasis removing, subduing swelling and relieving pain.Control and fall damage, incised wound, muscles and bones, all pains of trusted subordinate.Lump in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye.Select for use Eupolyphaga Seu Steleophaga to be because its nature and flavor are salty, cold.Slightly poisonous.Return Liver Channel.Energy removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.Selecting Flos Carthami for use is owing to its nature and flavor suffering, temperature.Go into the heart, Liver Channel.Promoting blood circulation to restore menstrual flow, amenorrhea is controlled in the blood stasis removing pain relieving, lump in the abdomen, difficult labour, stillborn fetus, lochia is more than, and the stasis of blood is had a pain, carbuncle, traumatic injury.Selecting Cortex Cinnamomi for use, have another name called CORTEX CINNAMOMI, is because its nature and flavor suffering, sweet, hot is returned kidney, spleen, urinary bladder channel, the complement sun, and warming the spleen and stomach, the removing accumulated cold promoting blood circulation is controlled decline of the fire from the gate of life, the YANG-depletion collapse, the colic of cold type renal mass, chills and pain of the waist and kness and empty sun are more floating, heat in the upper and cold in the lower.Select for use Herba speranskiae tuberculatae to be because its nature and flavor are sweet, nontoxic, dispel the wind, dehumidifying, Shujin, invigorate blood circulation, the analgesic function, dispelling the wind and dampness pathogens arthralgia pain, muscles and bones contracture, the disturbance of lower legs due to pathogenic cold and dampness, the bright toxic swelling of skin ulcer.Selecting Flos Caryophylli for use is owing to its nature and flavor suffering, temperature.Go into stomach, spleen, kidney channel.Warming middle-JIAO, warming the kidney, sending down the abnormal ascending QI.Control singultus, vomiting, regurgitation, dysentery, trusted subordinate's cold type of pain, mass beside the umbilicus, hernia, tinea disease.Selecting Moschus for use is owing to its nature and flavor suffering, temperature.Go into the heart, spleen, Liver Channel.Have one's ideas straightened out, ward off dirty, collateral dredging, dissipating blood stasis.Control apoplexy, syncope due to accumulation of phlegm, infantile convulsion, attacked by pestiferous factors unhappiness, trusted subordinate's sudden pain, the lump in the abdomen hypochondriac lump, traumatic injury, swollen ulcer drug.Select for use Borneolum Syntheticum to be because its nature and flavor are arduous, cold.Go into the heart, lung meridian.Logical all keys, the stagnated fire of loosing, removing nebula makes eye bright, reducing swelling and alleviating pain.Control the apoplexy locked mouth, calentura coma, infantile convulsion expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media, carbuncle, hemorrhoid, conjunctivitis, enterobiasis.Selecting Mentholum for use is owing to its nature and flavor suffering, and cold is nontoxic.Return lung meridian, dispelling wind, heat clearing away.Control affection due to external wind and heat, headache conjunctival congestion, pharyngalgia, toothache, skin pruritus due to wind pathogen.Select for use the Plumbum preparatium to be because its nature and flavor suffering is salty, cold, be included into the heart, spleen, Liver Channel, removing toxic substances and promoting granulation, eliminating phlegm down to arrest convulsion.Be used for carbuncle, ulcer, incised wound is hemorrhage, and the soup fire is burnt, and infantile convulsion is demented.Selecting Rhizoma Corydalis Decumbentis for use is owing to its nature and flavor hardship, little suffering, and temperature is returned Liver Channel, is used for apoplectic hemiplegia, traumatic injury, rheumatic arthritis, sciatica.Select for use Radix Asparagi to be because its nature and flavor sweetness and bitterness is cold, return lung, kidney channel, nourishing YIN to relieve dryness, lung heat clearing is promoted the production of body fluid, and is used for dryness of the lung dry cough, dry throat and mouth, dryness of the intestine constipation.
The amounts of components of medicine of the present invention also is to draw through the Test Summary of inventor by repeatedly, and drug dose all has curative effect preferably in following weight range:
Radix Angelicae Sinensis 15 grams-25 gram Pyritums 15 grams-25 grams
Sanguis Draxonis 15 grams-20 gram Olibanums 15 grams-20 grams
Myrrha 15 grams-25 gram Eupolyphaga Seu Steleophagas 13 grams-18 grams
Flos Carthami 10 grams-18 gram Cortex Cinnamomis 8 grams-12 grams
Herba speranskiae tuberculatae 28 grams-32 gram Flos Caryophyllis 8 grams-12 grams
Moschus 1 gram-5 gram Borneolum Syntheticums 5 grams-8 grams
Mentholum 5 grams-8 gram vegetable oil 1800 grams-2200 grams
Plumbum preparatium 700 grams-900 gram Rhizoma Corydalis Decumbentiss, 700 grams-900 grams
Radix Asparagi 500 grams-700 grams
Be preferably:
Radix Angelicae Sinensis 20 gram Pyritums 20 grams
Sanguis Draxonis 18 gram Olibanums 18 grams
Myrrha 18 gram Eupolyphaga Seu Steleophagas 15 grams
Flos Carthami 15 gram Cortex Cinnamomis 10 grams
Herba speranskiae tuberculatae 30 gram Flos Caryophyllis 10 grams
Moschus 3 gram Borneolum Syntheticums 6 grams
Mentholum 6 gram vegetable oil 800 grams
Plumbum preparatium 800 gram Rhizoma Corydalis Decumbentiss, 900 grams
Radix Asparagi 600 grams
Preparation method of the present invention is as follows, and it comprises the following steps:
One, preferred feedstock medicine
1, Radix Angelicae Sinensis: choose decontamination, clean, moistening dries in the air slightly to internal and external temperature when suitable, and section is dried;
2, Pyritum: outwash, knock fritter;
3, Sanguis Draxonis: wipe dust away, the knock fritter in winter dryness weather, is placed on and makes dryly in the Calx altar, takes advantage of crisp grinding into powder then;
4, Olibanum: remove impurity, be broken into fritter;
5, Myrrha: choose decontamination, break into fragment;
6, Eupolyphaga Seu Steleophaga: get former material, cleaning, drying;
7, Flos Carthami: choose clean impurity, remove stem and leaf, base of a fruit head, dry;
8, Cortex Cinnamomi: choose clean impurity, scrape off rough bark, the time spent smashes;
9, Herba speranskiae tuberculatae: clean, dry, chopping is used;
10, Flos Caryophylli: remove bennet, dry;
11, Moschus: soak into sachet with warm water, remove fur inner membrance impurity after severing, the time spent is got Moschus core porphyrize;
12, Borneolum Syntheticum: original is used as medicine;
13, Mentholum: get crude drug, remove impurity;
14, vegetable oil: get pure soy bean, elimination impurity;
15, Plumbum preparatium: pure lead is placed in the iron pan heats, fry movingly, utilize air to make it oxidation, pulverize use water rinse then, divides the end with the thickness powder, and the fine powder that drifts out through oxidation 24 hours, is ground into fine powder again, and filtration promptly;
16, Radix Asparagi: get crude drug, remove impurity and rotten blackout person, wash quickly is clean, dries in the air cutting, drying slightly;
17, Rhizoma Corydalis Decumbentis: get crude drug, remove impurity, clean, run through, cut sheet, drying.
Two, preparation
1, earlier vegetable oil is put into iron pan, endure heat when 50 spend, Radix Angelicae Sinensis, Pyritum, Sanguis Draxonis, Olibanum, Myrrha, Eupolyphaga Seu Steleophaga, Flos Carthami, Cortex Cinnamomi, Herba speranskiae tuberculatae, Flos Caryophylli are put into pot, high temperature decocts, and medicine is fried in shallow oil into the charcoal shape pull out;
2, oil cauldron is put in the Plumbum preparatium and decoct, as on fire, urgent need mouthful spray cold water is endured to the Plumbum preparatium when water becomes pearl, touches block anxious truce with hands;
When 3, treating pot interior Plumbum preparatium cold to 30 ℃, add after Borneolum Syntheticum, Moschus and top ten medicine charcoal stir, add again book lotus brain ointment;
4, above-mentioned ointment is split on the 200 plaster stypes 30 * 30 centimetres of every subsides.
Medicine of the present invention has blood circulation and promoting silt, reunion of bone, and the function of reducing swelling and alleviating pain, it is fast to be used for the treatment of miscellaneous fracture damage curative effect, the cure rate height.
The specific embodiment:
Below further set forth the beneficial effect of medicine of the present invention by testing example.These test examples comprise the observations of animal experiment and clinical trial.
The animal experiment report of [test example 1] medicine of the present invention
Get New Zealand man and exempt from 20, the male and female dual-purpose, body weight 2.0-2.5kg is divided into two groups, 10 every group, get New Zealand wherein one group be the normal amount toxicity test, another group is for the excess toxicity test.
The normal amount toxicity test: take out the rabbit abdominal part rabbit hair, get said medicine, spread on the rabbit abdominal part, once a day, each medication is subsides, continuous three days, observes 10 all no abnormal reactions of rabbit every day.
The excess toxicity test: take out the rabbit abdominal part rabbit hair, get the above-mentioned medicine for preparing, spread on the rabbit abdominal part, every day twice, each consumption is two subsides, and logotype three days there is no abnormal response.
Evidence, medicine of the present invention has no side effect.
The clinical observation of [test example 2] Drug therapy fracture and injury of the present invention
1, physical data
Accept out-patient's 70 examples for medical treatment, wherein male 49 examples, women 21 examples, 15 years old age-20 years old 10 example wherein, 21 years old-30 years old 25 examples, 31 years old-45 years old 20 examples, 15 examples more than 45 years old.
2, diagnostic criteria
Comminuted fracture: general pilosity is born in vehicle collision or the mechanical damage in the vehicle accident, and patient's arm or shank skeleton become to pulverize shape fracture or segmental defect.
Closed fracture: traumatic injury or other unexpected permanent disabilities.
3, Therapeutic Method
Debridement is changed dressings, and bone reduction sticks this cream, changes dressings cream once in per two days.
4, efficacy assessment standard
Produce effects:
The callus formation healing, the fracture para-position, pain disappears, and limb functional recover is freely.
Take a turn for the better: the callus formation healing, the fracture para-position, pain relief or idol have pain, limb function improving action.
Invalid: as not reach improvement standard person.
5, therapeutic outcome
Figure GSA00000007950500061
In above-mentioned treatment, with Drug therapy comminuted fracture of the present invention damage patient 40 examples, produce effects 37 examples as a result, obvious effective rate is 92.5%, 2 examples that take a turn for the better, improvement rate is 5%, invalid 1 example, total effective rate is 97.5%.
With the closed shape fracture and injury of Drug therapy of the present invention patient 30 examples, produce effects 28 examples as a result, obvious effective rate is 93.3%, 2 examples that take a turn for the better, improvement rate is 6.7%, total effective rate is 100%.

Claims (3)

1. setting bone and promoting blood flow plaster for the treatment of fracture and injury, it is characterized in that: it is by following weight
Crude drug in the scope is made:
Radix Angelicae Sinensis 15 grams-25 gram Pyritums 15 grams-25 grams
Sanguis Draxonis 15 grams-20 gram Olibanums 15 grams-20 grams
Myrrha 15 grams-25 gram Eupolyphaga Seu Steleophagas 13 grams-18 grams
Flos Carthami 10 grams-18 gram Cortex Cinnamomis 8 grams-12 grams
Herba speranskiae tuberculatae 28 grams-32 gram Flos Caryophyllis 8 grams-12 grams
Moschus 1 gram-5 gram Borneolum Syntheticums 5 grams-8 grams
Mentholum 5 grams-8 gram vegetable oil 1800 grams-2200 grams
Plumbum preparatium 700 grams-900 gram Rhizoma Corydalis Decumbentiss, 700 grams-900 grams
Radix Asparagi 500 grams-700 grams.
2. setting bone and promoting blood flow plaster according to claim 1, wherein the consumption of each crude drug is:
Radix Angelicae Sinensis 20 gram Pyritums 20 grams
Sanguis Draxonis 18 gram Olibanums 18 grams
Myrrha 18 gram Eupolyphaga Seu Steleophagas 15 grams
Flos Carthami 15 gram Cortex Cinnamomis 10 grams
Herba speranskiae tuberculatae 30 gram Flos Caryophyllis 10 grams
Moschus 3 gram Borneolum Syntheticums 6 grams
Mentholum 6 gram vegetable oil 800 grams
Plumbum preparatium 800 gram Rhizoma Corydalis Decumbentiss, 900 grams
Radix Asparagi 600 grams.
3. the preparation method of setting bone and promoting blood flow plaster according to claim 1 and 2, it is characterized in that: it comprises the following steps:
One, preferred feedstock medicine
(1) Radix Angelicae Sinensis: choose decontamination, clean, moistening dries in the air slightly to internal and external temperature when suitable, and section is dried;
(2) Pyritum: outwash, knock fritter;
(3) Sanguis Draxonis: wipe dust away, the knock fritter in winter dryness weather, is placed on and makes dryly in the Calx altar, takes advantage of crisp grinding into powder then;
(4) Olibanum: remove impurity, be broken into fritter;
(5) Myrrha: choose decontamination, break into fragment;
(6) Eupolyphaga Seu Steleophaga: get former material, cleaning, drying;
(7) Flos Carthami: choose clean impurity, remove stem and leaf, base of a fruit head, dry;
(8) Cortex Cinnamomi: choose clean impurity, scrape off rough bark, the time spent smashes;
(9) Herba speranskiae tuberculatae: clean, dry, chopping is used;
(10) Flos Caryophylli: remove bennet, dry;
(11) Moschus: soak into sachet with warm water, remove fur inner membrance impurity after severing, the time spent is got Moschus core porphyrize;
(12) Borneolum Syntheticum: original is used as medicine;
(13) Mentholum is got crude drug, removes impurity;
(14) vegetable oil: get pure soy bean, elimination impurity;
(15) Plumbum preparatium: pure lead is placed in the iron pan heats, fry movingly, utilize air to make it oxidation, pulverize use water rinse then, divides the end with the thickness powder, and the fine powder that drifts out through oxidation 24 hours, is ground into fine powder again, and filtration promptly;
(16) Radix Asparagi: get crude drug, remove impurity and rotten blackout person, wash quickly is clean, dries in the air cutting, drying slightly;
(17) Rhizoma Corydalis Decumbentis: get crude drug, remove impurity, clean, run through, cut sheet, drying;
Two, preparation
(1) earlier vegetable oil is put into iron pan, endure heat when 50 spend, Radix Angelicae Sinensis, Pyritum, Sanguis Draxonis, Olibanum, Myrrha, Eupolyphaga Seu Steleophaga, Flos Carthami, Cortex Cinnamomi, Herba speranskiae tuberculatae, Flos Caryophylli are put into pot, high temperature decocts, and medicine is fried in shallow oil into the charcoal shape pull out;
(2) oil cauldron is put in the Plumbum preparatium and decoct, as on fire, urgent need mouthful spray cold water is endured to the Plumbum preparatium when water becomes pearl, touches block anxious truce with hands;
When (3) treating pot interior Plumbum preparatium cold to 30 ℃, add after Borneolum Syntheticum, Moschus stir with top ten medicine charcoal, add again the oily brain of book lotus ointment;
(4) above-mentioned ointment is split on the 200 plaster stypes 30 * 30 centimetres of every subsides.
CN2010101024787A 2010-01-25 2010-01-25 Setting bone and promoting blood flow plaster for treating fractures and injuries and preparation method thereof Expired - Fee Related CN101745026B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103372182A (en) * 2012-04-16 2013-10-30 苏州仁耀商务信息咨询有限公司 Automatic vibration electromagnetic wave massage plaster and preparation method thereof
CN103372179A (en) * 2012-04-13 2013-10-30 苏州仁耀商务信息咨询有限公司 Plaster preparation for relieving pain, activating blood, softening hard mass and removing blood stasis, and preparation method thereof
CN104524470A (en) * 2015-01-12 2015-04-22 姜济业 Blood circulation invigorating fracture setting paste for treating fracture and preparation method thereof
CN109999168A (en) * 2019-04-17 2019-07-12 深圳市正曜健康医疗有限公司 One analgesic bone liquid medicine formula

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103372179A (en) * 2012-04-13 2013-10-30 苏州仁耀商务信息咨询有限公司 Plaster preparation for relieving pain, activating blood, softening hard mass and removing blood stasis, and preparation method thereof
CN103372182A (en) * 2012-04-16 2013-10-30 苏州仁耀商务信息咨询有限公司 Automatic vibration electromagnetic wave massage plaster and preparation method thereof
CN103372182B (en) * 2012-04-16 2015-11-25 苏州仁耀传统养生科技有限公司 Automatic vibration electromagnetic wave massage plaster and preparation method thereof
CN104524470A (en) * 2015-01-12 2015-04-22 姜济业 Blood circulation invigorating fracture setting paste for treating fracture and preparation method thereof
CN109999168A (en) * 2019-04-17 2019-07-12 深圳市正曜健康医疗有限公司 One analgesic bone liquid medicine formula

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