CN101731250B - Fenazaquin-containing acaricidal composition - Google Patents

Fenazaquin-containing acaricidal composition Download PDF

Info

Publication number
CN101731250B
CN101731250B CN 201010004931 CN201010004931A CN101731250B CN 101731250 B CN101731250 B CN 101731250B CN 201010004931 CN201010004931 CN 201010004931 CN 201010004931 A CN201010004931 A CN 201010004931A CN 101731250 B CN101731250 B CN 101731250B
Authority
CN
China
Prior art keywords
fenazaquin
butyl ether
ether urea
urea
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN 201010004931
Other languages
Chinese (zh)
Other versions
CN101731250A (en
Inventor
刘忠义
曹明章
朱卫锋
桂艳男
程凯
孔建
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DONGGUAN RUIDEFENG BIOLOGICAL SCIENCE AND TECHNOLOGY Co Ltd
Original Assignee
DONGGUAN RUIDEFENG BIOLOGICAL SCIENCE AND TECHNOLOGY Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DONGGUAN RUIDEFENG BIOLOGICAL SCIENCE AND TECHNOLOGY Co Ltd filed Critical DONGGUAN RUIDEFENG BIOLOGICAL SCIENCE AND TECHNOLOGY Co Ltd
Priority to CN 201010004931 priority Critical patent/CN101731250B/en
Publication of CN101731250A publication Critical patent/CN101731250A/en
Application granted granted Critical
Publication of CN101731250B publication Critical patent/CN101731250B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention discloses a fenazaquin-containing acaricidal composition. The acaricidal composition comprises fenazaquin and diafenthiuron serving as active ingredients, wherein the mass-portion ratio of fenazaquin to diafenthiuron is between 20:1 and 1:80. The compounding of fenazaquin and diafenthiuron has obvious synergism and can reduce dosage and delay the generation of the drug resistance of pest mites. The composition can be used to prevent and control the pest mites on fruit trees, cotton, vegetables and flowers and other crops.

Description

A kind of miticide composition that contains fenazaquin
Technical field
The present invention relates to a kind of compound acaricide composition, be specially a kind of miticide composition that contains fenazaquin.
Background technology
Fenazaquin: English common name Fenazaquin, chemical name: 4-spy-butyl benzene ethyl quinazoline, molecular formula: C 20H 22N 20Its structural formula is:
Figure G2010100049310D00011
This medicine is the quinolines miticide, through mitochondria and the chromosome set 1 of action of contace poison in insect cell, occupies the abutment of ubiquinone, and citrus, European red mite are had the better prevention effect, and the lasting period is long, to natural enemies security.Do not have cross resistance with existing miticide, be particularly suitable for preventing and treating the pest mite class that existing miticide is produced resistance.But under the selection pressure of a large amount of dispensers of single agent, agent is easy to generate pesticide resistance to the evil mite to the fenazaquin list, and fenazaquin to prevent and treat the cost of resistance evil mite higher relatively.
Butyl ether urea: another name methamidophos, boccaccio, English common name Diafenthiuron, chemical name: 1-tertiary butyl-3-(2,6-diisopropyl-4-Phenoxyphenyl) thiocarbamide, molecular formula: C 23H 32N 2OS.The butyl ether urea is a kind of novel Thiourea efficient insecticide, miticide, have tag, stomach toxicity, interior suction and fumigation action; Low toxicity changes the material with insecticidal activity under ultraviolet light, the insect that has produced serious resistance on the vegetables is had stronger activity.Can prevent and treat aphid, aleyrodid, leafhopper, noctuidae pests and evil mite on various crop and the flowers.But the agent of butyl ether urea list is used and is easy to generate pesticide resistance, and the performance of its drug effect receives weather effect big.
Mite pest is because its breeding cycle is short, and breeding amount is big, and mobility is little, and the selfing degree is high, is easy to generate resistance especially.Show that according to people's results of study to the Chunan County panonychus citri in 2007 such as Xaisur China local panonychus citri has improved 25 times to the resistance of pyridaben.In the serious zone of some mite classes harm, single agent control such as pyridaben, four mite piperazines, azacyclotin evil mite dosage is big, cost is high, weak effect, environmental pollution are serious.
Composite through the compound of different effects mechanism is to delay the effective means that the evil mite produces resistance and the improvement of resistance evil mite.Compounded combination with synergistic effect, the dose that can reduce agricultural chemicals is a spraying times, delays the drug-fast generation of disease mite.
Summary of the invention
The objective of the invention is: a kind of complex composition that contains fenazaquin is provided, and said composition has obvious synergistic effect, and the control spectrum is wide, can delay the characteristics that evil mite pesticide resistance produces.Another object of the present invention is to provide the application of said composition on agricultural evil mite.
The present invention realizes through following technical scheme:
A large amount of compound screening test and field trial that the inventor carries out after unexpected discovery fenazaquin and butyl ether urea are composite, show obvious synergistic effect to the evil mite, can delay the drug-fast generation of evil mite.
A kind of miticide composition with synergistic effect is characterized in that containing fenazaquin and butyl ether urea, and the mass ratio of fenazaquin and butyl ether urea is 20: 1-1: 80, and the preferred mass ratio is 10: 1-1: 30.
Described miticide composition, wherein the active ingredient total content is 5%-90%, all the other are auxiliary element.
The present composition can adopt prior art; As required; Active ingredient is added auxiliary agent and excipients process agricultural according to production technology well known by persons skilled in the art and go up available any formulation, preferred dosage form is missible oil, wetting powder, suspending agent, water dispersible granules and microemulsion.
Beneficial effect of the present invention is: 1. fenazaquin and the composite miticide composition of butyl ether urea, have obvious synergistic effect, and reduce effective ingredient consumption, improve control efficiency; 2. the acaricidal activity composition of different effects mechanism is composite, has synergistic effect, can effectively delay the drug-fast generation of evil mite, and can be used for the improvement of resistance evil mite; Lasting period long, reduced dosage and medication number of times, practice thrift cost, and reduce pollution environment.
Embodiment
Following examples are to further specify of the present invention, but the present invention is not limited thereto.
(1) prescription and preparation processing embodiment.What active component adopted in the embodiment of the invention is former medicine of 99% fenazaquin and the former medicine of 95% butyl ether urea.
Embodiment 1:42% fenazaquin butyl ether urea wetting powder
Fenazaquin 40.40g
Butyl ether urea 2.11g
Lauryl sodium sulfate (wetting agent) 3g
Alkylnaphthalene sulfonate formaldehyde condensation products (dispersant) 5g
Kaolin (filler) is mended to 100g
Active component, various auxiliary agent and filler etc. are fully mixed in the ratio of prescription, promptly get 42% fenazaquin butyl ether urea wetting powder through airslide disintegrating mill pulverizing, screening.(mass ratio of fenazaquin and butyl ether urea is 20: 1)
Embodiment 2:22% fenazaquin butyl ether urea suspending agent
Fenazaquin 20.20g
Butyl ether urea 2.11g
Lignosulfonates (dispersant) 4g
Ethylene glycol (antifreezing agent) 4g
Silicone oil (antifoaming agent) 0.4g
Deionized water is mended to 100g
By the prescription requirement, the former medicine of pulverizing in advance and carrier, surfactant, antifreezing agent, water etc. are added in the husky mill still, porphyrize is again through the mixed suspending agent that gets of high speed shear.(mass ratio of fenazaquin and butyl ether urea is 10: 1)
Embodiment 3:24% fenazaquin butyl ether urea microemulsion
Fenazaquin 20.20g
Butyl ether urea 4.22g
N-Methyl pyrrolidone (cosolvent) 10g
Calcium dodecyl benzene sulfonate (emulsifier) 8g
Triphen ethyl-phenol polyoxyethylene (emulsifier) 5g
Deionized water complements to 100g
Former medicine, cosolvent, emulsifier are added together, make and be dissolved into even oil phase, slowly add in the entry under stirring,, be chilled to room temperature and make microemulsion again through the rapid phase inversion of agitating heating.(mass ratio of fenazaquin and butyl ether urea is 5: 1)
Embodiment 4:30% fenazaquin butyl ether urea missible oil
Fenazaquin 15.15g
Butyl ether urea 15.79g
Calcium dodecyl benzene sulfonate (emulsifier) 4g
Phenethyl phenol polyethenoxy ether (emulsifier) 4g
Xylol (solvent) is mended to 100g
To contain active component, emulsifier and solvent etc., add mixing kettle successively, stir, get 30% fenazaquin butyl ether urea missible oil in the ratio of filling a prescription.(mass ratio of fenazaquin and butyl ether urea is 1: 1)
Embodiment 5:60% fenazaquin butyl ether urea wetting powder
Fenazaquin 10.10g
Butyl ether urea 52.63g
Lauryl sodium sulfate (wetting agent) 3g
Alkylnaphthalene sulfonate formaldehyde condensation products (dispersant) 5g
Kaolin (filler) is mended to 100g
Active component, various auxiliary agent and filler etc. are fully mixed in the ratio of prescription, after airslide disintegrating mill is pulverized, promptly get 60% fenazaquin butyl ether urea wetting powder through screening again.(mass ratio of fenazaquin and butyl ether urea is 1: 5)
Embodiment 6:33% fenazaquin butyl ether urea missible oil
Fenazaquin 3.03g
Butyl ether urea 31.58g
Calcium dodecyl benzene sulfonate (emulsifier) 4g
Phenethyl phenol polyethenoxy ether (emulsifier) 4g
Xylol (solvent) is mended to 100g
Former medicine, emulsifier and the soluble additive etc. that will contain active component add mixing kettle successively in the ratio of filling a prescription, and stir, and get 33% fenazaquin butyl ether urea missible oil.(mass ratio of fenazaquin and butyl ether urea is 1: 10)
Embodiment 7:62% fenazaquin butyl ether urea suspending agent
Fenazaquin 2.11g
Butyl ether urea 60.60g
Lignosulfonates (dispersant) 4g
Ethylene glycol (antifreezing agent) 4g
Silicone oil (antifoaming agent) 0.4g
Deionized water is mended to 100g
By the prescription requirement, the former medicine of pulverizing in advance and carrier, surfactant, antifreezing agent, water etc. are added in the husky mill still, porphyrize is again through the mixed suspending agent that gets of high speed shear.(mass ratio of fenazaquin and butyl ether urea is 1: 30)
Embodiment 8:81% fenazaquin diafenthiuron water dispersible granule
Fenazaquin 1.01g
Butyl ether urea 84.21g
Neopelex (wetting agent) 3g
Lignin sodium sulphate (dispersant) 4g
Alkylnaphthalene sulfonate formaldehyde condensation products (dispersant) 2g
Urea (disintegrant) 5g
Diatomite (filler) is mended to 100g
Said mixture is evenly mixed, and comminution by gas stream adds suitable quantity of water and kneading, and the mixture pelleting of gained promptly gets 81% fenazaquin diafenthiuron water dispersible granule.(mass ratio of fenazaquin and butyl ether urea is 1: 80)
(2) biological activity determination of the present composition and the test of pesticide effectiveness
1. Toxicity Determination
With the cotton tetranychid is subjects; Employing leaf dish spray-on process (with reference to " NY/T 1154.13-2008 agricultural chemicals indoor bioassay test rule insecticide. the 13rd part: leaf dish spray-on process "), the synergistic effect of measuring fenazaquin and the composite different proportion of butyl ether urea is big or small.Co-toxicity coefficient (CTC value) according to the abundant method calculation composition of Sun Yun:
Actual measurement toxicity index (ATI)=(standard medicament LC 50/ confession reagent agent LC 50) * 100
The percentage composition of B in percentage composition+B medicament toxicity index * mixture of A in theoretical toxicity index (TTI)=A medicament toxicity index * mixture
Co-toxicity coefficient (CTC)=[mixture actual measurement toxicity index (the ATI)/theoretical toxicity index (TTI) of mixture] * 100
When CTC≤80, then the composition performance is for antagonism, and when 80<CTC<120, then the composition performance is for summation action, and when CTC>=120, then the composition performance is synergistic effect.
Toxicity Determination on the composite cotton tetranychid of table 1 fenazaquin and butyl ether urea
Handle LC 50(mg/L) ATI TTI CTC
Fenazaquin 14.9 100
The butyl ether urea 24.62 60.52
Fenazaquin 20: butyl ether urea 1 8.97 166.1 98.1 169.3
Fenazaquin 10: butyl ether urea 1 8.21 181.5 96.4 188.2
Fenazaquin 5: butyl ether urea 1 7.47 199.5 93.4 213.5
Fenazaquin 1: butyl ether urea 1 7.52 198.1 80.3 246.9
Fenazaquin 1: butyl ether urea 5 8.69 171.5 67.1 255.5
Fenazaquin 1: butyl ether urea 10 9.75 152.8 64.1 238.4
Fenazaquin 1: butyl ether urea 30 11.78 126.5 61.8 204.7
Fenazaquin 1: butyl ether urea 80 18.56 80.3 61.0 131.6
Fenazaquin and butyl ether urea composite Toxicity Determination result on the cotton tetranychid show; Fenazaquin and butyl ether urea are composite at ratio range 20: 1-1: between 80, can both show synergistic effect, especially 10: 1-1: between 30; Synergistic effect is remarkable, and co-toxicity coefficient is at (table 1) more than 180.
2, the composite field controling test of fenazaquin and butyl ether urea to the cotton tetranychid
The whole strain spray-on process of knapsack sprayer is adopted in test; Zone relatively uniformly takes place in two spotted spider mite in the field, and every group of medicament selected the 5 strain cottons object of making investigation, and makes marks; Carry out the investigation of insect population radix, then carry out even spraying according to the extension rate and the application method of experimental scheme.Respectively at checking in 1 day, 7 days and 21 days behind the medicine, calculate field efficacy.
The composite field efficacy of table 2 fenazaquin and butyl ether urea to the cotton tetranychid
Figure G2010100049310D00071
30% fenazaquin butyl ether urea missible oil (embodiment 4) 3000 22.5g fenazaquin+22.5 butyl ether ureas 85.4 91.7 93.3
60% fenazaquin butyl ether urea wetting powder (embodiment 5) 2000 22.5g fenazaquin+112.5g butyl ether urea 93.4 98.2 95.1
33% fenazaquin butyl ether urea missible oil (embodiment 6) 2000 6.75g fenazaquin+67.5g butyl ether urea 90.3 95.4 92.9
62% fenazaquin butyl ether urea suspending agent (embodiment 7) 2000 4.5g fenazaquin+135g butyl ether urea 91.1 94.8 90.9
81% fenazaquin diafenthiuron water dispersible granule (embodiment 8) 2000 22.5g fenazaquin+200g butyl ether urea 90.2 94.3 91.8
CK (clear water contrast) 0 0 0 0 0
Result of the test to the cotton tetranychid shows that fenazaquin and butyl ether urea are 20: 1-1: in 80 the ratio range, have synergistic effect.Can find out from table 2, compare with butyl ether urea list agent preventive effect with fenazaquin that compound drug is under the situation that effective ingredient consumption reduces, preventive effect increases.After the dispenser 1 day, the preventive effect of each compound drug was all more than 80%, and maximum preventive effect is 93.4% (embodiment 4), is higher than the preventive effect of fenazaquin list agent, explains that compound drug promotes with respect to the agent of fenazaquin list on quick-acting to some extent, has synergistic effect; After the dispenser 7 days, the preventive effect of each compound drug was all more than 85%, and especially the preventive effect of embodiment 4 reaches 98.2%, explained that fenazaquin and butyl ether urea are composite to have an obvious synergistic effect; After the dispenser 21 days, the preventive effect of each compound drug was higher than 70.6% of butyl ether urea list agent all more than 90%, explains that aspect lasting effect, the lasting effect of compound drug is better, and lasting effect is strong, can reduce the whole growth spraying times in season, reduced the control cost.
The result of Toxicity Determination and field efficiency test shows, fenazaquin and butyl ether urea be composite to have synergistic effect, can reduce dosage, reduces and pollutes; Synergistic effect is obvious, and lasting effect strengthens, and can reduce the whole growth spraying times in season, delays the evil mite and develops immunity to drugs, and can reduce the control cost simultaneously, the protection environment.

Claims (4)

1. a miticide composition is characterized in that active ingredient contains fenazaquin and butyl ether urea, and wherein the mass fraction ratio of fenazaquin and butyl ether urea is 20: 1-1: 80.
2. miticide composition according to claim 1, the mass fraction ratio that it is characterized in that active ingredient fenazaquin and butyl ether urea is 10: 1-1: 30.
3. miticide composition according to claim 1 is characterized in that formulation is missible oil, wetting powder, water dispersible granules, suspending agent or microemulsion.
4. be used for the control of cotton tetranychid according to each described miticide composition of claim 1 to 3.
CN 201010004931 2010-01-20 2010-01-20 Fenazaquin-containing acaricidal composition Active CN101731250B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 201010004931 CN101731250B (en) 2010-01-20 2010-01-20 Fenazaquin-containing acaricidal composition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 201010004931 CN101731250B (en) 2010-01-20 2010-01-20 Fenazaquin-containing acaricidal composition

Publications (2)

Publication Number Publication Date
CN101731250A CN101731250A (en) 2010-06-16
CN101731250B true CN101731250B (en) 2012-12-12

Family

ID=42455662

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 201010004931 Active CN101731250B (en) 2010-01-20 2010-01-20 Fenazaquin-containing acaricidal composition

Country Status (1)

Country Link
CN (1) CN101731250B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107372522A (en) * 2017-08-31 2017-11-24 江西正邦生物化工有限责任公司 A kind of composition pesticide containing fenazaquin

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101366379A (en) * 2007-06-29 2009-02-18 拜尔农作物科学股份公司 Acaricidal active substance combinations
CN101653134A (en) * 2009-08-03 2010-02-24 东莞市瑞德丰生物科技有限公司 Mite-killing composition containing fenazaquin

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101366379A (en) * 2007-06-29 2009-02-18 拜尔农作物科学股份公司 Acaricidal active substance combinations
CN101653134A (en) * 2009-08-03 2010-02-24 东莞市瑞德丰生物科技有限公司 Mite-killing composition containing fenazaquin

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
刘刚.沈阳化工研究院成功研制25%丁醚脲·哒螨灵悬浮剂.《农药市场信息》.2008,(第10期),31. *
周艳丽.新型杀螨剂喹螨醚的合成.《农药科学与管理》.2005,第26卷(第6期),33-34. *
赵玉伟.二斑叶螨和朱砂叶螨对常用杀螨剂的敏感性比较.《农药》.2006,第45卷(第6期),418-419. *

Also Published As

Publication number Publication date
CN101731250A (en) 2010-06-16

Similar Documents

Publication Publication Date Title
CN101380008A (en) Disinsection composition with synergistic action
CN101642117A (en) Pesticidal composition with synergistic effect
CN101647463A (en) Insecticidal and acaricidal composition containing spirodiclofen
CN101637158A (en) Insecticidal composition with synergistic action
CN101485329B (en) Agricultural chemical composition for disinsection and use thereof
CN103947655B (en) A kind of Pesticidal combination comprising ivermectin and spiral shell mite ester
CN101589720B (en) Pesticide composition containing indoxacarb
CN101406197B (en) Compositional mite-killing composition containing spirodiclofen and ivermectin
CN101731228A (en) Fenazaquin-containing acaricidal composition
CN102228044B (en) Insecticidal composition containing sufluoxime
CN102246778A (en) Efficiency enhanced insecticidal composition, and application thereof
CN103651506B (en) A kind of Pesticidal combination containing penta pyrrole worm guanidine and nimbin
CN101653126B (en) Mite-killing composition containing fenazaquin
CN101731250B (en) Fenazaquin-containing acaricidal composition
CN101653134A (en) Mite-killing composition containing fenazaquin
CN101380002A (en) Insecticide and acaricide composition containing spirodiclofen
CN101473828B (en) Agricultural chemical composition for disinsection and use thereof
CN104814031B (en) A kind of Pesticidal combination containing butene-fipronil and clothianidin
CN101653120B (en) Mite-killing composition containing fenazaquin
CN102696631B (en) Synergistic acaricidal composition containing etoxazole and chlorfenapyr
CN101653125A (en) Compound pesticide composition containing pymetrozine
CN101669479A (en) Mite-killing combination
CN102771494A (en) Insecticidal composition containing Guadipyr and macrolide pesticide
CN101653144B (en) Pesticide composition with synergistic action
CN104255735A (en) Pyridalyl and tetra-chlorantraniliprole compounded insecticidal composition

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant