CN101721436A - Compound fermented aweto capsule and preparation method thereof - Google Patents

Compound fermented aweto capsule and preparation method thereof Download PDF

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Publication number
CN101721436A
CN101721436A CN200910186522A CN200910186522A CN101721436A CN 101721436 A CN101721436 A CN 101721436A CN 200910186522 A CN200910186522 A CN 200910186522A CN 200910186522 A CN200910186522 A CN 200910186522A CN 101721436 A CN101721436 A CN 101721436A
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China
Prior art keywords
fermented
powder
capsule
ganoderma lucidum
compound
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CN200910186522A
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Chinese (zh)
Inventor
付志高
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JIANGXI BAISHEN PHARMACEUTICAL GROUP CO Ltd
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JIANGXI BAISHEN PHARMACEUTICAL GROUP CO Ltd
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Priority to CN200910186522A priority Critical patent/CN101721436A/en
Publication of CN101721436A publication Critical patent/CN101721436A/en
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Abstract

The invention relates to a compound fermented aweto capsule and a preparation method thereof. The compound fermented aweto capsule is prepared by mixing fermented aweto fungus powder, fermented ganoderma lucidum fungus powder and magnesium stearate. The formula (by weight) of the compound fermented aweto capsule is as follows: the fermented aweto fungus powder accounts for 46-86%, the fermented ganoderma lucidum fungus powder accounts for 53.2-13.2%, the magnesium stearate accounts for 0.8%, the fermented aweto fungus powder, the fermented ganoderma lucidum fungus powder and the magnesium stearate are combined to prepare the compound fermented aweto capsule, and each capsule is 0.5g. Ganoderan (calculated by glucan) in the fermented ganoderma lucidum fungus powder is not less than 2.54g/100g; total triterpene (calculated by ursolic acid) is not less than 2.64g/100g. The content of adenosine in the fermented aweto fungus powder is not less than 180mg/100g. The invention is suitable for preparing and producing the compound fermented aweto capsule.

Description

Compound fermented aweto capsule and preparation method thereof
Technical field
The present invention relates to a kind of compound fermented aweto capsule and preparation method thereof, belong to the Medicines and Health Product technical field.
Background technology
Fermented Cordyceps powder (peacilomyce hepiahi (Paecilomyces hepiali Chen etDai, sp.Nov), claim Cordyceps fungus powder again, it is to utilize the microorganism means, the mycothallus of natural cordyceps sporophore is separated through artificial, after purification and the cultivation and fermentation, obtain the Cordyceps fungal mycelium, then mycelium is carried out drying and produce the pure mycopowder of Cordyceps, the kind that can be used for the fungus strain list of health food for State Food and Drug Administration's " regulation (trying) is declared and evaluated to the Mycophyta health food ": peacilomyce hepiahi (Paecilomyces hepiali Chen et Dai, sp.Nov).Fermented Cordyceps powder can the kidney invigorating be protected lung, and secret lean gas has enhancing immunity function, alleviating physical fatigue function.
Fermented Ganoderma Lucidum powder (Ganoderma lucidum) derives from raw material---the fermented Ganoderma Lucidum powder that Jiangxi Baishen Medicine Group Co.,Ltd is used to produce ganoderma lucidum extract (the accurate word Z36021927 of traditional Chinese medicines), fermented Ganoderma Lucidum powder has mind tranquilizing and the heart calming, the invigorating the spleen and regulating the stomach effect, be used for insomnia forgetfulness, physical weakness, neurasthenia etc.
Publication number CN101095701 and publication number CN101095702 disclose a kind of graininess that contains Hirsutella hepiali Chen et Shen-fermented Cordyceps powder or lamellar medicine and preparation method thereof respectively, and it contains major ingredient: Hirsutella hepiali Chen et Shen-fermented Cordyceps powder; Adjuvant: wetting agent and/or binding agent, disintegrating agent, lubricant.Notification number CN1171633 discloses extremely preparation method of a kind of aweto capsule, and aweto capsule is that cultural mycelium powder 6-12 part is formulated by wild Chinese caterpillar fungus powder 1-3 part.
What sell in the market is that the health food made of primary raw material is many with the fermented Cordyceps powder, but is still rarely to arrive on the health food market of the capsule formulation made of primary raw material with fermented Cordyceps powder, fermented Ganoderma Lucidum powder.
Summary of the invention
The objective of the invention is,, propose a kind of fermented Cordyceps powder health care of both having had, have a kind of comprehensive health-care product of fermented Ganoderma Lucidum powder health care again according to fermented Cordyceps powder and fermented Ganoderma Lucidum powder health care separately.
Technical scheme of the present invention is,
Compound fermented aweto capsule of the present invention is formed by fermented Cordyceps powder, fermented Ganoderma Lucidum powder, magnesium stearate assembly.Its prescription (by weight) is: fermented Cordyceps powder accounts for 46-86%, and fermented Ganoderma Lucidum powder accounts for 53.2-13.2%, and magnesium stearate accounts for 0.8%, with its combined preparation compound fermented aweto capsule, every 0.5g.
The used fermented Cordyceps powder (being Cordyceps fungus powder) of the present invention is to utilize the microorganism means, with the mycothallus of natural cordyceps sporophore after artificial separation, purification and cultivation and fermentation, obtain the Cordyceps fungal mycelium, then mycelium is carried out drying and produce the pure mycopowder of Cordyceps, the fermented Cordyceps powder effective component is mainly adenosine, its content 〉=250mg/100g.
The used fermented Ganoderma Lucidum powder of the present invention picks up from the red ganoderma in the natural surroundings, therefrom isolates strain with the modern biotechnology method, and the method for reuse biofermentation obtains Ganoderma mycelium, the Ganoderma mycelium drying pulverize fermented Ganoderma Lucidum powder.The fermented Ganoderma Lucidum powder functional component is mainly ganoderan, ganoderma lucidum triterpene compounds, wherein ganoderan (in glucosan) 〉=8.0g/100g in the fermented Ganoderma Lucidum powder; Total triterpene (in ursolic acid) 〉=10.0g/100g.
The used magnesium stearate of the present invention is made fluidizer in prescription.Because in capsule was produced, the flowability of powder was very big to the influential effect of capsule charge, in order to increase the capsule 's content flowability, has added an amount of magnesium stearate and has made fluidizer.
The preparation technological process of production as shown in drawings.Mainly comprise: raw material sieves, mixes, always mixes, adorns capsule etc.
1, raw material sieves: take by weighing fermented Cordyceps powder by formula ratio, cross 65 mesh sieves, and standby.Take by weighing fermented Ganoderma Lucidum powder by formula ratio, cross 65 mesh sieves, standby.
2, mix: the fermented Cordyceps powder that will sieve, fermented Ganoderma Lucidum powder are fed in the two dimensional motion mixer of dried and clean, mix 20min, make the zymophyte powder compound.
3, total mixing: take by weighing magnesium stearate by formula ratio, carry out always mixing with the zymophyte powder compound.Behind the mixing, collect total batch mixing and pack in the Plastic Drum of the clean plastic bag of liner, the outer Status Flag that posts marker material title, quantity, lot number, specification etc. of bucket is sent into the capsule intermediate station and is stored.
4, dress capsule: total batch mixing and Capsules are added respectively separately in the hopper, operate full-automatic hard capsule filling machine and carry out the capsule filling, during the operate capsule filling machine, at any time note capsule loading (0.5g/ grain), the capsule that the adjusting loading comes out filling meets the quality standard requirement, in time picks out the underproof capsule of outward appearance.
The present invention's beneficial effect compared with the prior art is, have the double health function of fermented Cordyceps powder and fermented Ganoderma Lucidum powder concurrently by the compound fermented aweto capsule of the present invention's preparation, protect lung, secret lean gas with the fermented Cordyceps powder the kidney invigorating in the prescription, be aided with the fermented Ganoderma Lucidum powder invigorating the spleen and regulating the stomach, the two share, have synergism, the effect of the kidney invigorating lung moistening, replenishing QI to invigorate the spleen, enhancing immunity is arranged.
The present invention is suitable for the preparation and the production of compound fermented aweto capsule.
Description of drawings
Be illustrated as compound fermented aweto capsule preparation technology flow chart of the present invention.
The specific embodiment
The embodiment of the invention:
1, supplementary material is selected
1. fermented Ganoderma Lucidum powder
The fermented Ganoderma Lucidum powder quality is answered the regulation of accord with Q/BSY002-2007 fermented Ganoderma Lucidum powder, and this quality standard is defined as the effective ingredient index with crude polysaccharides, total triterpene, and the fermented Ganoderma Lucidum powder functional component is ganoderan, ganoderma lucidum triterpene compounds.Ganoderan in the fermented Ganoderma Lucidum powder (in glucosan) 〉=8.0g/100g; Total triterpene (in ursolic acid) 〉=10.0g/100g.
2. fermented Cordyceps powder
Fermented Cordyceps powder is answered accord with Q/ZWZ001-2005 " great river peacilomyce hepiahi powder (fermented Cordyceps powder) " specification requirement, wherein adenosine 〉=250.0mg/100g.
3. magnesium stearate
Magnesium stearate should meet the regulation of two ones of Pharmacopoeia of the People's Republic of China versions in 2005.
2, composition of raw materials
In 1000, fermented Cordyceps powder 330g; Fermented Ganoderma Lucidum powder 166g; Magnesium stearate 4g is with 1000 of its combined preparation fermented Cordyceps powder ganoderma lucidum powder capsules, every 0.5g.
3, preparation process
1. raw material sieves: take by weighing fermented Cordyceps powder by formula ratio, cross 65 mesh sieves, and standby.Take by weighing fermented Ganoderma Lucidum powder by formula ratio, cross 65 mesh sieves, standby.
2. mix: the fermented Cordyceps powder that will sieve, fermented Ganoderma Lucidum powder are fed in the two dimensional motion mixer of dried and clean, mix 20min, make the zymophyte powder compound.
3. always mix: take by weighing magnesium stearate by formula ratio, carry out always mixing with the zymophyte powder compound.Behind the mixing, collect total batch mixing and pack in the Plastic Drum of the clean plastic bag of liner, the outer Status Flag that posts marker material title, quantity, lot number, specification etc. of bucket is sent into the capsule intermediate station and is stored.
4. adorn capsule: total batch mixing and Capsules are added respectively separately in the hopper, operate full-automatic hard capsule filling machine and carry out the capsule filling, during the operate capsule filling machine, at any time note capsule loading (0.5g/ grain), the capsule that the adjusting loading comes out filling meets the quality standard requirement, in time picks out the underproof capsule of outward appearance.
5. adorn polish behind the capsule, common process such as inspection of semifinished product, inside and outside packing, product inspection, warehouse-in, finish whole technological processes of product.

Claims (3)

1. compound fermented aweto capsule and preparation method thereof is characterized in that, described compound fermented aweto capsule is formed by fermented Cordyceps powder, fermented Ganoderma Lucidum powder, magnesium stearate assembly; Its prescription is by weight: fermented Cordyceps powder accounts for 46-86%, and fermented Ganoderma Lucidum powder accounts for 53.2-13.2%, and magnesium stearate accounts for 0.8%, with its combined preparation compound fermented aweto capsule, every 0.5g.
2. compound fermented aweto capsule according to claim 1 and preparation method thereof is characterized in that, ganoderan in the described fermented Ganoderma Lucidum powder (in glucosan) 〉=8.0g/100g; Total triterpene (in ursolic acid) 〉=10.0g/100g.
3. compound fermented aweto capsule according to claim 1 and preparation method thereof is characterized in that, adenosine content 〉=250mg/100g in the described fermented Cordyceps powder.
CN200910186522A 2009-11-19 2009-11-19 Compound fermented aweto capsule and preparation method thereof Pending CN101721436A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN200910186522A CN101721436A (en) 2009-11-19 2009-11-19 Compound fermented aweto capsule and preparation method thereof

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Application Number Priority Date Filing Date Title
CN200910186522A CN101721436A (en) 2009-11-19 2009-11-19 Compound fermented aweto capsule and preparation method thereof

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CN101721436A true CN101721436A (en) 2010-06-09

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102551058A (en) * 2012-01-17 2012-07-11 北京东方红航天生物技术股份有限公司 Chinese medicinal health-care product with function of enhancing immunity
CN102860501A (en) * 2011-07-07 2013-01-09 韩淑娜 Formula and preparation method of lucid ganoderma cordyceps militaris maitake health protection dissolved medicines
CN104997815A (en) * 2015-07-08 2015-10-28 哈尔滨瑞康源生物科技有限公司 Cordyceps sinensis and Mythic Fungus fermentation powder composite lozenge and preparation method thereof
CN105146371A (en) * 2015-07-17 2015-12-16 徐州黎明食品有限公司 Black garlic and Chinese caterpillar fungus granules and preparation method thereof
CN105166866A (en) * 2015-07-17 2015-12-23 徐州黎明食品有限公司 Black garlic and Mythic Fungus composition

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102860501A (en) * 2011-07-07 2013-01-09 韩淑娜 Formula and preparation method of lucid ganoderma cordyceps militaris maitake health protection dissolved medicines
CN102860501B (en) * 2011-07-07 2013-08-28 韩淑娜 Formula and preparation method of lucid ganoderma cordyceps militaris maitake health protection dissolved medicines
CN102551058A (en) * 2012-01-17 2012-07-11 北京东方红航天生物技术股份有限公司 Chinese medicinal health-care product with function of enhancing immunity
CN104997815A (en) * 2015-07-08 2015-10-28 哈尔滨瑞康源生物科技有限公司 Cordyceps sinensis and Mythic Fungus fermentation powder composite lozenge and preparation method thereof
CN105146371A (en) * 2015-07-17 2015-12-16 徐州黎明食品有限公司 Black garlic and Chinese caterpillar fungus granules and preparation method thereof
CN105166866A (en) * 2015-07-17 2015-12-23 徐州黎明食品有限公司 Black garlic and Mythic Fungus composition
CN105146371B (en) * 2015-07-17 2018-11-20 徐州黎明食品有限公司 A kind of black garlic cordyceps sinensis particle and preparation method thereof

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Application publication date: 20100609