CN102233082B - Preparation method of compound traditional Chinese medicine concentrated pill for resisting fatigue and delaying senility - Google Patents
Preparation method of compound traditional Chinese medicine concentrated pill for resisting fatigue and delaying senility Download PDFInfo
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- CN102233082B CN102233082B CN201010158052.3A CN201010158052A CN102233082B CN 102233082 B CN102233082 B CN 102233082B CN 201010158052 A CN201010158052 A CN 201010158052A CN 102233082 B CN102233082 B CN 102233082B
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Abstract
The invention relates to a preparation method of a compound traditional Chinese medicine concentrated pill for resisting fatigue and delaying senility. The preparation method comprises the following steps of: taking 10g of eucommia, 10g of desertliving cistanche, 10g of morinda root, 5g of achyranthes root, 5g of japanese sweetflag, 5g of small fennel, 5g of dogwood, 5g of magnolia vine fruit, 5g of Chinese yam, 5g of prepared rehmannia root, 5g of Chinese wolfberry and 5g of paper mulberry fruit, and extracting to prepare extract; taking 5g of jujube, 5g of tuckahoe, 5g of Chinese yam and 5g of prepared rehmannia root and preparing to obtain dry powder, mixing the dry powder with the prepared extract, and adding hot distilled water according to the proportion of 2:1 to prepare blank pills; putting 30kg of the blank pills into a sugar coating pan, adding 1000ml of gelatin of 5%; drying 0.5-2kg of talcum powder by an isolating layer, adding 500g of warm syrup of 70%, drying 0.5-2kg of talcum powder as the powder coating layer for later use; and adding 105g of black ferric oxide to 8kg of syrup of 70% to prepare a mixed syrup, putting into the sugar coating pan, covering the pan for 10 minutes, adding 60g of wax powder and polishing for 40 minutes to obtain pills. Pills prepared by the method have good stability, long shelf life and high curative effect.
Description
Technical field
The present invention relates to a kind of Chinese medicinal preparation method, specifically the preparation method of the Chinese medicine of resisting fatigue, slow down aging.
Traditional Chinese medical science recipe Huanshao pill, has good result aspect resisting fatigue and slow down aging, and dosage form is honeyed pill at present, but this dosage form dose is large, and drug effect is slow.
Summary of the invention
Object of the present invention, is to provide a kind of preparation method of resisting fatigue Chinese medicine of Delaying Senility compound recipe concentrated pill, has improved curative effect.
The technical scheme adopting is:
A preparation method for resisting fatigue, Chinese medicine of Delaying Senility compound recipe concentrated pill, comprises following processing step:
Pill is processed and made to medical material, Cortex Eucommiae 10-15g, Radix Achyranthis Bidentatae 5-10g, Rhizoma Acori Graminei 5-10g, Herba Cistanches 10-15g, Radix Morindae Officinalis 10-15g, Fructus Foeniculi 5-10g, mountain Fructus Corni 5-10g, Fructus Schisandrae Chinensis 5-10g, Rhizoma Dioscoreae 5-10g, Radix Rehmanniae Preparata 5-10g, Fructus Lycii 5-10g, Fructus Broussonetiae 5-10g, 10 taste medical materials, the aquiferous ethanol reflux, extract, that is 30-90% by the concentration of 8 times of amounts of medical material 1-3 time, each extraction time is respectively 0.5-2.0 hour, merging filtrate, decompression recycling ethanol, medicinal liquid is condensed into the extractum that relative density is 1.05-1.15 (40 ℃ of mensuration), dry (the inlet temperature 80-110 ℃ of spraying, outlet temperature 140-160 ℃), obtain extractum, standby.Get Fructus Jujubae 5-10g, Poria 5-10g, Rhizoma Dioscoreae 5-10g and Radix Rehmanniae Preparata 5-10g, at 60-80 ℃ of temperature, dry weightlessness approximately 15%, mix with the above-mentioned extractum making, be ground into fine powder, after fine powder stirs, cross 80 mesh sieve 2 times, make medicated powder standby; In medicated powder, add hot distilled water, the proportioning of medicated powder and hot distilled water (80-100 ℃) is 2: 1, stirs and makes soft material, with automatic traditional Chinese medicine palletizing machine, pushes pill, and wet ball Weight control is every of 0.2g.The wet ball making rotary rolling 15min in coating pan, to strengthen its roundness.60 ℃～70 ℃ oven dry, arrange plain ball sorting, remove broken ball and roundness chump, and irradiation sterilization, obtains plain ball.
Get the plain ball 30kg after sterilizing, put in coating pan, get 5% gelatine size 1000ml, Pulvis Talci 0.5-2kg, divides to add for 3-10 time and makes sealing coat, blows 40 ℃ of hot air dryings.After layer to be isolated is dry, add the about 500g of 70% warm syrup, Pulvis Talci 0.5-2kg, gradation adds to add for 3-10 time makes sub-coat, blows 40 ℃ of hot air dryings.Separately 105g Black Rouge is added in 8kg70% syrup, make mixing molasses, minute 12～15 times (10～15min/ a time) adds in coating pan, bag color clothing layer.After vexed pot 10min, add wax powder 60g, polishing 40min obtains outward appearance rounding, bright fine and smooth finished product ball.
This process using part medicinal material extract, beats powder with residue medical material, makes concentrated pill.Finished-product volume significantly reduces, and it is original 40% that clothes for patients dose is reduced to, and carry and transport all more convenient.
The pill that adopts the present invention to make, good stability, long shelf-life, curative effect is high.
The specific embodiment
Embodiment mono-
A kind of resisting fatigue, the preparation method of Chinese medicine of Delaying Senility compound recipe concentrated pill, to get Cortex Eucommiae 10g, Radix Achyranthis Bidentatae 5g, Rhizoma Acori Graminei 5g, Herba Cistanches 10g, Radix Morindae Officinalis 10g, Fructus Foeniculi 5g, mountain Fructus Corni 5g, Fructus Schisandrae Chinensis 5g, Rhizoma Dioscoreae 5g, Radix Rehmanniae Preparata 5g, Fructus Lycii 5g, Fructus Broussonetiae 5g, with 80% aquiferous ethanol of 8 times of amounts of medical material, extract 2 times, extraction time is respectively 2 hours, merging filtrate, decompression recycling ethanol, medicinal liquid is condensed into the extractum that relative density is 1.05-1.10 (40 ℃ of mensuration), dry (the inlet temperature 80-100 ℃ of spraying, outlet temperature 140-160 ℃), obtain extractum, standby.Get Fructus Jujubae 5g, Poria 5g, Rhizoma Dioscoreae 5 and Radix Rehmanniae Preparata 5g, at 60-80 ℃ of temperature, dry weightlessness approximately 15%, mix with the above-mentioned extractum making, be ground into fine powder, after fine powder stirs, cross 80 mesh sieve 2 times, make medicated powder standby; In medicated powder, add hot distilled water (80-100 ℃), the proportioning of medicated powder and hot distilled water is 2: 1, stirs and makes soft material, with automatic traditional Chinese medicine palletizing machine, pushes pill, and wet ball Weight control is every of 0.2g.The wet ball making rotary rolling 15min in coating pan, to strengthen its roundness.60 ℃～70 ℃ oven dry, arrange plain ball sorting, remove broken ball and roundness chump, and irradiation sterilization, obtains plain ball.
Get the plain ball 30kg after sterilizing, put in coating pan, get 5% gelatine size 1000ml, Pulvis Talci 0.5-2kg, divides to add for 4-8 time and makes sealing coat, blows 40 ℃ of hot air dryings.After layer to be isolated is dry, add the about 500g of 70% warm syrup, Pulvis Talci 1kg, gradation adds to add for 4-8 time makes sub-coat, blows 40 ℃ of hot air dryings.Separately 105g Black Rouge is added in 8kg70% syrup, make mixing molasses, minute 12～15 times (10～15min/ a time) adds in coating pan, bag color clothing layer.After vexed pot 10min, add wax powder 60g, polishing 40min obtains outward appearance rounding, bright fine and smooth finished product ball.
Embodiment bis-
The preparation method of a kind of resisting fatigue, Chinese medicine of Delaying Senility compound recipe concentrated pill, to get Cortex Eucommiae 11g, Radix Achyranthis Bidentatae 6g, Rhizoma Acori Graminei 8g, Herba Cistanches 13g, Radix Morindae Officinalis 14g, Fructus Foeniculi 7g, mountain Fructus Corni 8g, Fructus Schisandrae Chinensis 9g, Fructus Lycii 6g, Fructus Broussonetiae 7g, with 80% aquiferous ethanol of 8 times of amounts of medical material, extract 2 times, extraction time is respectively 2 hours, merging filtrate, decompression recycling ethanol, medicinal liquid is condensed into the extractum that relative density is 1.05-1.10 (40 ℃ of mensuration), dry (the inlet temperature 80-100 ℃ of spraying, outlet temperature 140-160 ℃), obtain extractum, standby.Another by remaining Fructus Jujubae 8g, Poria 7g, Rhizoma Dioscoreae 6g and Radix Rehmanniae Preparata 8g, at 60-80 ℃ of temperature, dry weightlessness approximately 15%, mix with the above-mentioned extractum making, be ground into fine powder, after stirring, fine powder crosses 80 mesh sieve 2 times, make medicated powder standby; In medicated powder, add hot distilled water (80-100 ℃), the proportioning of medicated powder and hot distilled water is 2: 1, stirs and makes soft material, with automatic traditional Chinese medicine palletizing machine, pushes pill.The wet ball making rotary rolling 15min in coating pan, to strengthen its roundness.60 ℃～70 ℃ oven dry, arrange plain ball sorting, remove broken ball and roundness chump, and irradiation sterilization, obtains plain ball.
Get the plain ball 30kg after sterilizing, put in coating pan, get 5% gelatine size 1000ml, Pulvis Talci 0.5-2kg, divides to add for 4-8 time and makes sealing coat, blows 40 ℃ of hot air dryings.After layer to be isolated is dry, add the about 500g of 70% warm syrup, Pulvis Talci 1kg, gradation adds to add for 4-8 time makes sub-coat, blows 40 ℃ of hot air dryings.Separately 105g Black Rouge is added in 8kg70% syrup, make mixing molasses, minute 12～15 times (10～15min/ a time) adds in coating pan, bag color clothing layer.After vexed pot 10min, add wax powder 60g, polishing 40min obtains outward appearance rounding, bright fine and smooth finished product ball.
Embodiment tri-
A kind of resisting fatigue, the preparation method of Chinese medicine of Delaying Senility compound recipe concentrated pill, to get Cortex Eucommiae 15g, Radix Achyranthis Bidentatae 10g, Rhizoma Acori Graminei 10g, Herba Cistanches 15g, Radix Morindae Officinalis 15g, Fructus Foeniculi 10g, mountain Fructus Corni 10g, Fructus Schisandrae Chinensis 10g, Rhizoma Dioscoreae 10g, Radix Rehmanniae Preparata 10g, Fructus Lycii 10g, Fructus Broussonetiae 10g, with 80% aquiferous ethanol of 8 times of amounts of medical material, extract 2 times, extraction time is respectively 2 hours, merging filtrate, decompression recycling ethanol, medicinal liquid is condensed into the extractum that relative density is 1.05-1.10 (40 ℃ of mensuration), dry (the inlet temperature 80-100 ℃ of spraying, outlet temperature 140-160 ℃), obtain extractum, standby.Get Fructus Jujubae 5g, Poria 5g, Rhizoma Dioscoreae 5 and Radix Rehmanniae Preparata 5g, at 60-80 ℃ of temperature, dry weightlessness approximately 15%, mix with the above-mentioned extractum making, be ground into fine powder, after fine powder stirs, cross 80 mesh sieve 2 times, make medicated powder standby; In medicated powder, add hot distilled water (80-100 ℃), the proportioning of medicated powder and hot distilled water is 2: 1, stirs and makes soft material, with automatic traditional Chinese medicine palletizing machine, pushes pill.The wet ball making rotary rolling 15min in coating pan, to strengthen its roundness.60 ℃～70 ℃ oven dry, arrange plain ball sorting, remove broken ball and roundness chump, and irradiation sterilization, obtains plain ball.
Get the plain ball 30kg after sterilizing, put in coating pan, get 5% gelatine size 1000ml, Pulvis Talci 0.5-2kg, divides to add for 4-8 time and makes sealing coat, blows 40 ℃ of hot air dryings.After layer to be isolated is dry, add the about 500g of 70% warm syrup, Pulvis Talci 1kg, gradation adds to add for 4-8 time makes sub-coat, blows 40 ℃ of hot air dryings.Separately 105g Black Rouge is added in 8kg70% syrup, make mixing molasses, minute 12～15 times (10～15min/ a time) adds in coating pan, bag color clothing layer.After vexed pot 10min, add wax powder 60g, polishing 40min obtains outward appearance rounding, bright fine and smooth finished product ball.
Claims (1)
1. the preparation method of a resisting fatigue, Chinese medicine of Delaying Senility compound recipe concentrated pill, it is characterized in that getting Cortex Eucommiae 11g, Radix Achyranthis Bidentatae 6g, Rhizoma Acori Graminei 8g, Herba Cistanches 13g, Radix Morindae Officinalis 14g, Fructus Foeniculi 7g, mountain Fructus Corni 8g, Fructus Schisandrae Chinensis 9g, Fructus Lycii 6g, Fructus Broussonetiae 7g, with 80% aquiferous ethanol of 8 times of amounts of medical material, extract 2 times, extraction time is respectively 2 hours, merging filtrate, decompression recycling ethanol, medicinal liquid is condensed into the extractum that 40 ℃ of surveys of relative density are 1.05-1.10, spraying is dry, inlet temperature 80-100 ℃, outlet temperature 140-160 ℃, obtains extractum, standby; Another by remaining Fructus Jujubae 8g, Poria 7g, Rhizoma Dioscoreae 6g and Radix Rehmanniae Preparata 8g, at 60-80 ℃ of temperature, dry weightlessness 15%, mix with the above-mentioned extractum making, be ground into fine powder, after stirring, fine powder crosses 80 mesh sieve 2 times, make medicated powder standby; The hot distilled water that adds 80-100 ℃ in medicated powder, the proportioning of medicated powder and hot distilled water is 2:1, stirs and makes soft material, with automatic traditional Chinese medicine palletizing machine, pushes pill; The wet ball making rotary rolling 15min in coating pan, 60 ℃～70 ℃ oven dry, arrange plain ball sorting, remove broken ball, and irradiation sterilization, obtains plain ball;
Get the plain ball 30kg after sterilizing, put in coating pan, get 5% gelatine size 1000ml, Pulvis Talci 0.5-2kg, divides to add for 4-8 time and makes sealing coat, blows 40 ℃ of hot air dryings; After layer to be isolated is dry, add 70% warm syrup 500g, Pulvis Talci 1kg, gradation adds to add for 4-8 time makes sub-coat, blows 40 ℃ of hot air dryings; Separately 105g Black Rouge is added in 8kg70% syrup, make mixing molasses, divide 12～15 times, each 10～15min adds in coating pan, bag color clothing layer; After vexed pot 10min, add wax powder 60g, the polishing 40min ball that gets product.
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| CN201010158052.3A CN102233082B (en) | 2010-04-28 | 2010-04-28 | Preparation method of compound traditional Chinese medicine concentrated pill for resisting fatigue and delaying senility |
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| CN201010158052.3A CN102233082B (en) | 2010-04-28 | 2010-04-28 | Preparation method of compound traditional Chinese medicine concentrated pill for resisting fatigue and delaying senility |
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| CN102233082B true CN102233082B (en) | 2014-04-02 |
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| CN104222412A (en) * | 2014-08-18 | 2014-12-24 | 郭雪山 | Health herbal tea capable of improving immunity and preparation method thereof |
| CN112167617A (en) * | 2020-06-29 | 2021-01-05 | 武汉林宝莱生物科技有限公司 | Female anti-aging whitening pill and preparation method thereof |
| CN112891505A (en) * | 2021-04-25 | 2021-06-04 | 曾雨晴 | Spleen-tonifying and kidney-tonifying composition, preparation method and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1788772A (en) * | 2004-12-15 | 2006-06-21 | 修涞贵 | Traditional Chinese medicine oral liquid for building spleen and kidney, nourishing heart and calming nerve |
| CN101695539A (en) * | 2009-10-28 | 2010-04-21 | 重庆三峡云海药业有限责任公司 | Medicament for deferring senility and preparation method thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1788772A (en) * | 2004-12-15 | 2006-06-21 | 修涞贵 | Traditional Chinese medicine oral liquid for building spleen and kidney, nourishing heart and calming nerve |
| CN101695539A (en) * | 2009-10-28 | 2010-04-21 | 重庆三峡云海药业有限责任公司 | Medicament for deferring senility and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 国家药品监督管理局.还少丹.《国家药品标准地标升国标肾系》.2002, * |
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