CN105031201A - Medicament for treating bad symptoms caused by heart-fire hyperactivity and preparation method thereof - Google Patents
Medicament for treating bad symptoms caused by heart-fire hyperactivity and preparation method thereof Download PDFInfo
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- CN105031201A CN105031201A CN201510399412.1A CN201510399412A CN105031201A CN 105031201 A CN105031201 A CN 105031201A CN 201510399412 A CN201510399412 A CN 201510399412A CN 105031201 A CN105031201 A CN 105031201A
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Abstract
The invention discloses medicament for treating bad symptoms caused by heart-fire hyperactivity. The medicament is characterized by being formulated by 150g of coptis root, 150g of Baikal skullcap root, 200g of kudzuvine root, 200g of red-rooted salvia root, 50g of ginseng, 200g of Chinese angelica root, 200g of rhizome acori graminei, 200g of albizia flower, 100g of lily flower, 300g of spina date seed, 250g of fossil fragment and 250g of oyster. The drug is a capsule, content of the drug is brown powder and is fragrant in smell and bitter in taste, and the drug has a quite good effect in tranquilizing, refreshing and relieving depression and is mainly used for treating symptoms like insomnia, vexation and dizziness caused by heart-fire hyperactivity.
Description
Technical field
The present invention relates to field of medicaments, especially relate to a kind of medicine being used for the treatment of insomnia caused by hyperactivity of heart-fire, the symptom such as vexed, dizzy.
Background technology
Disease name.Can send out because the fire of feelings will is interior, or because of six climate exopathogens stagnation of fire in the interior, or surfeit is hot, crosses and takes temperature compensation and cause.Disease sees dysphoria with smothery sensation in the heart, impatient insomnia, and aphthous stomatitis pain is thirsty, red tongue, and rapid pulse very then sparkles impairing the lung the moon and sees spitting of blood, epistaxis etc.Control suitable clearing heart fire, or double removing heat from blood.
Caused by flaming of heart-fire in the interior, the clinical syndrome that is main manifestations with vexed insomnia, aphtha of the mouth and tongue etc.Be found in stranguria with blood, be insomnia, cardiopalmus, and the multiple oral ulcer of doctor trained in Western medicine, urinary system infection, hyperthyroidism, neurosis and manic type psychosis etc.The heart-yin heart-yang balance coordination, maintains the functional activity of heart governing blood and vessels, main mind jointly.If burning hot heresy invades, or the product that monophagia is pungent usually, or anger is depressed, then can heat-transformation fire-transformation, inside disturbs the mind, forms hyperactivity of heart-fire card.The clinical manifestation of hyperactivity of heart-fire card is with vexed, and insomnia, aphtha of the mouth and tongue, very then rotten to the corn, red of red tongue thorn, rapid pulse, yellowish urine, burning on urination etc. are feature.Concrete manifestation can be divided into again flaming of heart-fire in the interior, flaming up of heart-fire and the heart transferring pathogenic heat to the small intestine three kinds according to the difference of Deterioration mechanism.Heart channel is intimately flourishing, and the mind is disturbed, and gently then has a sleepless night, dreaminess, heavy then raving are dazed and confused, constant laughter; Burning hot Sheng, therefore rapid pulse, the very then burning hot absurd row of forcing blood, and see various hemorrhage; Because of flaming of heart-fire in the interior in the heart, the conscious ambition of patient is unhappy.Flaming up of heart-fire, visible aphtha of the mouth and tongue, very then rotten to the corn, the broken pain of the tip of the tongue, red of red tongue thorn etc.The heart transferring pathogenic heat to the small intestine, visible yellowish or reddish urine, scorching hot twinge of urinating, even the card of the excess-heat in the small intestines such as hematuria.The treatment of hyperactivity of heart-fire card take clearing heart fire as principle.As the epistaxis haematemesis person caused for flaming of heart-fire in the interior, XIEXIN TANG should be used; Flaming up of heart-fire, optional coptos bolus for clearing the upper heat; Heart-fire is moved in small intestinal person, generally selects daochi powder; If have bleeding concurrently, the product of cooling blood for hemostasis can be added.
Summary of the invention
The object of this invention is to provide a kind of medicine being used for the treatment of insomnia caused by hyperactivity of heart-fire, the symptom such as vexed, dizzy, and disclose its pharmaceutical methods.
To achieve these goals, technical scheme of the present invention is such: the medicine of the ill symptoms of a kind for the treatment of caused by hyperactivity of heart-fire, and its formula is as follows:
Rhizoma Coptidis 150g Radix Scutellariae 150g Radix Puerariae 200g Radix Salviae Miltiorrhizae 200g
Radix Ginseng 50g Radix Angelicae Sinensis 200g Rhizoma Acori Graminei 200g Flos Albiziae 200g
Bulbus Lilii 100g Semen Ziziphi Spinosae 300g Os Draconis 250g Concha Ostreae 250g.
A method for the medicine of manufacturing claims 1, is characterized in that: comprise the following steps:
A, above 12 tastes, except Os Draconis, each 100g of Concha Ostreae are ground into except fine powder, get Radix Angelicae Sinensis, Rhizoma Acori Graminei etc. two taste add water that to extract volatile oil for subsequent use for 6-8 times amount respectively, the another device of the aqueous solution after distillation is collected;
B, get Rhizoma Coptidis, Radix Scutellariae, Radix Puerariae, Radix Salviae Miltiorrhizae, people participate in 70% ethanol 4 times amount reflux, extract, twice, three hours first times, second time two hours, filter, filter and merge, decompression recycling ethanol, being concentrated into relative density is 1.30(50 degree Celsius) thick paste;
C, get each 150g of Bulbus Lilii, Flos Albiziae, Semen Ziziphi Spinosae, Os Draconis and Concha Ostreae and said extracted volatile oil and alcohol reflux after merge with medicinal residues, 10 times amount that add water decoct secondary, each 1.5 hours, filter, filter and merge, add distillate, being concentrated into relative density is 1.30(50 degree Celsius) thick paste;
D, above-mentioned thick paste to be merged, dry, pulverize into fine powder;
E, volatile oil is sprayed in Os Draconis, Concha Ostreae fine powder, with above-mentioned medicated powder stirring and evenly mixing, sieves, incapsulate, make 1000, to obtain final product.
Detailed description of the invention
Embodiment
Medication name of the present invention is called imperial Fructus Jujubae capsule, is below its standard recipe:
Rhizoma Coptidis 150g Radix Scutellariae 150g Radix Puerariae 200g Radix Salviae Miltiorrhizae 200g
Radix Ginseng 50g Radix Angelicae Sinensis 200g Rhizoma Acori Graminei 200g Flos Albiziae 200g
Bulbus Lilii 100g Semen Ziziphi Spinosae 300g Os Draconis 250g Concha Ostreae 250g.
Its pharmaceutical methods is:
A, above 12 tastes, except Os Draconis, each 100g of Concha Ostreae are ground into except fine powder, get Radix Angelicae Sinensis, Rhizoma Acori Graminei etc. two taste add water that to extract volatile oil for subsequent use for 6-8 times amount respectively, the another device of the aqueous solution after distillation is collected;
B, get Rhizoma Coptidis, Radix Scutellariae, Radix Puerariae, Radix Salviae Miltiorrhizae, people participate in 70% ethanol 4 times amount reflux, extract, twice, three hours first times, second time two hours, filter, filter and merge, decompression recycling ethanol, being concentrated into relative density is 1.30(50 degree Celsius) thick paste;
C, get each 150g of Bulbus Lilii, Flos Albiziae, Semen Ziziphi Spinosae, Os Draconis and Concha Ostreae and said extracted volatile oil and alcohol reflux after merge with medicinal residues, 10 times amount that add water decoct secondary, each 1.5 hours, filter, filter and merge, add distillate, being concentrated into relative density is 1.30(50 degree Celsius) thick paste;
D, above-mentioned thick paste to be merged, dry, pulverize into fine powder;
E, volatile oil is sprayed in Os Draconis, Concha Ostreae fine powder, with above-mentioned medicated powder stirring and evenly mixing, sieves, incapsulate, make 1000, to obtain final product.
pre-treatment of raw material operating process and process conditions
rhizoma Coptidis
Clean: medical material is put on sorting table, reject impurity and dis-medicinal part, visual inspection free from admixture.
Washing: Rhizoma Coptidis is put into medicine frame and put wash pond, gets express developed totally, by dry for water sky.
Dry: Rhizoma Coptidis is put into heated-air circulation oven drip pan, temperature controls at 70 DEG C ~ 80 DEG C, dry.
Storage: the medicinal polythene film bag of clean medical material is sealed, puts and only expect storehouse.
radix Scutellariae
Clean: medical material is put on sorting table, reject impurity and dis-medicinal part, visual inspection free from admixture.
Storage: the medicinal polythene film bag of clean medical material is sealed, puts and only expect storehouse.
radix Puerariae
Clean: medical material is put on sorting table, reject impurity and dis-medicinal part, visual inspection free from admixture.
Storage: the medicinal polythene film bag of clean medical material is sealed, puts and only expect storehouse.
radix Salviae Miltiorrhizae
Clean: medical material is put on sorting table, reject impurity and dis-medicinal part, visual inspection free from admixture.
Storage: the medicinal polythene film bag of clean medical material is sealed, puts and only expect storehouse.
radix Ginseng
Clean: medical material is put on sorting table, reject impurity and dis-medicinal part, visual inspection free from admixture.
Washing: Radix Ginseng is put into medicine frame and put wash pond, gets express developed totally, by dry for water sky.
Dry: Radix Ginseng to be put into heated-air circulation oven drip pan, baking temperature 70 DEG C ~ 80 DEG C, dry.
Storage: the medicinal polythene film bag of clean medical material is sealed, puts and only expect storehouse.
radix Angelicae Sinensis
Clean: medical material is put on sorting table, reject impurity and dis-medicinal part, visual inspection free from admixture.
Storage: the medicinal polythene film bag of clean medical material is sealed, puts and only expect storehouse.
rhizoma Acori Graminei
Clean: medical material is put on sorting table, reject impurity and dis-medicinal part, visual inspection free from admixture.
Storage: the medicinal polythene film bag of clean medical material is sealed, puts and only expect storehouse.
flos Albiziae
Clean: medical material is put on sorting table, reject impurity and dis-medicinal part, visual inspection free from admixture.
Washing: Flos Albiziae is put into medicine frame and put wash pond, gets express developed totally, by dry for water sky.
Dry: Flos Albiziae to be put into heated-air circulation oven drip pan, baking temperature 70 DEG C ~ 80 DEG C, dry.
Storage: the medicinal polythene film bag of clean medical material is sealed, puts and only expect storehouse.
bulbus Lilii
Clean: medical material is put on sorting table, reject impurity and dis-medicinal part, visual inspection free from admixture.
Storage: the medicinal polythene film bag of clean medical material is sealed, puts and only expect storehouse.
semen Ziziphi Spinosae
Clean: medical material is put on sorting table, reject impurity and dis-medicinal part, visual inspection free from admixture.
Washing: Semen Ziziphi Spinosae is put into medicine frame and put wash pond, gets express developed totally, by dry for water sky.
Dry: Semen Ziziphi Spinosae to be put into heated-air circulation oven drip pan, baking temperature 70 DEG C ~ 80 DEG C, dry.
Storage: the medicinal polythene film bag of clean medical material is sealed, puts and only expect storehouse.
os Draconis
Clean: medical material is put on sorting table, reject impurity and dis-medicinal part, visual inspection free from admixture.
Storage: the medicinal polythene film bag of clean medical material is sealed, puts and only expect storehouse.
concha Ostreae
Clean: medical material is put on sorting table, reject impurity and dis-medicinal part, visual inspection free from admixture.
Storage: the medicinal polythene film bag of clean medical material is sealed, puts and only expect storehouse.
Note: if when crude drug is bought, is the decoction pieces after processing, the process of preparing Chinese medicine, all manages by clean medical material.Chinese crude drug after circulating water should be used to wash selection, must not be used for washing other medical materials with the water crossed, and different Chinese crude drugs must not wash simultaneously in same container.
production operation process and process conditions
batching: check whether operation room has " production licence "; Electronic platform scale whether within the verification phase, switch on power whether normal; Whether production technology file, bath manufacturing records be complete, confirms to meet the requirements.Take clean medical material by pre-treatment instruction sheet, Rhizoma Coptidis 180.00kg, Radix Scutellariae 180.00kg, Radix Puerariae 240.00kg, Radix Salviae Miltiorrhizae 240.00kg, Radix Ginseng 60.00kg are denoted as reflux, extract, material; Radix Angelicae Sinensis 240.00kg, Rhizoma Acori Graminei 240.00kg are denoted as and hang oils material; Os Draconis 120.00kg, Concha Ostreae 120.00kg are denoted as comminuting matter; Bulbus Lilii 120.00kg, Flos Albiziae 240.00kg, Semen Ziziphi Spinosae 360.00kg, Os Draconis 180.00kg, Concha Ostreae 180.00kg are denoted as decoction material.
Check whether operation room has " production licence ", and whether multi-function extractor is normal; Whether production technology file, bath manufacturing records be complete, confirms to meet the requirements; Fetch that stream extracts material Rhizoma Coptidis, Radix Scutellariae, Radix Puerariae, Radix Salviae Miltiorrhizae, Radix Ginseng are put in multi-function extractor, reflux, extract, twice, first time adds 70% ethanol 4 times amount, reflux 3 hours, adds 70% ethanol 4 times amount for the second time, refluxes 2 hours.After extraction terminates, merge secondary decocting liquid, filter, extracting solution is deposited in storage tank.Decompression recycling ethanol, being concentrated into relative density is 1.30(50 DEG C) thick paste, medicinal residues are continued to employ.Attention: Rhizoma Coptidis, Radix Ginseng, before backflow, are first broken into coarse granule, decoct a drug wrapped.Operating process is undertaken by multi-functional extraction concentrated group standard operating procedure.Process conditions: this post is general production area, has air draft, draining, water vapour control device, the material of Decocting pot and pipeline is rustless steel.Technical parameter: boil the time: one decocts 3 hours, and two decoct 2 hours.Steam pressure 0.05 ~ 0.1MPa after boiling.
Get and hang oils material Radix Angelicae Sinensis Pu and put in multi-function extractor, add drinking water 6 times amount, distill 4.5 hours, collect volatile oil, distillation rear solution puts into receiver, stand-by.Medicinal residues decoct twice, add drinking water 10 times amount at every turn, decoct 1.5 hours.Filter, merging filtrate.Get and hang oils work stone Rhizoma Acori Graminei and put in multi-function extractor, add drinking water 6 times, distill 4.5 hours, collect volatile oil, distillation rear solution puts into receiver, stand-by.Medicinal residues decoct twice, add drinking water 10 times amount at every turn, decoct 1.5 hours.Filter, merging filtrate.
Decoct: get and decoct material Bulbus Lilii, Semen Ziziphi Spinosae, Flos Albiziae, Os Draconis, Concha Ostreae, drop in multi-function extractor, decoct twice with medicinal residues after reflux, extract, add drinking water 10 times amount at every turn, decoct 1.5 hours.Filter, merging filtrate.
concentrated
Check whether operation room has " production licence "; Whether economic benefits and social benefits decompression evaporator is normal; Whether production technology file, bath manufacturing records be complete, confirms to meet the requirements.
Draw Aqueous extracts, aqueous solution after distillation, by filtrate gradation suction concentrator, unlatching cooling water, steam valve, vacuum pump carry out concentrating under reduced pressure, control steam pressure and be no more than 0.10MPa, vacuum pressure controls at-0.06 ~-0.08MPa, and temperature controls, at 65 DEG C ~ 75 DEG C, to operate and undertaken by enriched standard rule of operation.Being concentrated into relative density is 1.30(50 DEG C) fluid extract, receive cream in clean area, load in clean polyethylene drum, treat that room temperature is down to by fluid extract, enter freezer and preserve.
Process conditions: this post is general production area, has air draft, draining, water vapour control device, the material of concentration tank and pipeline is rustless steel.Receive cream in D level clean area, temperature 18-26 DEG C, relative humidity 45-65%.
Technical parameter: steam pressure is no more than 0.10MPa, vacuum pressure controls at-0.06 ~-0.08MPa, and temperature controls at 65 DEG C ~ 75 DEG C.
heat-wind circulate drying
Check whether operation room has " production licence "; Whether heated-air circulation oven is normal; Whether production technology file, bath manufacturing records be complete, confirms to meet the requirements.
By aqueous extract, alcohol extractum, stand dish is put in heated-air circulation oven, 70 ~ 80 DEG C of dryings.Time dry, stand disc thickness is 2 ~ 3cm, within 2 hours, stirs once, and after drying about 6h, (stand dish, the time of stirring are disregarded) pull-out charging tray dries in the air cool, and rewinding, loads cleaning bag.Moisture Control, about 4%, to obtain final product.
Technical parameter: baking temperature 70 ~ 80 DEG C, drying time is about 6h.
pulverize
Check whether operation room has " production licence "; Pulverize unit, whether vibrosieve is normal; Whether production technology file, bath manufacturing records be complete, confirms to meet the requirements.By broken for dried cream powder mistake 80 mesh sieve, pack.By Os Draconis, Concha Ostreae co-grinding, cross 80 mesh sieves, pack.Process conditions: this post is D level clean area, temperature 18-26 DEG C, relative humidity 45-65%.Equipment material is rustless steel.Technical parameter: nylon screen, order number: 80 orders.
material (preparation)
Check whether operation room has " production licence "; Electronic platform scale whether within the verification phase, switch on power whether normal; Whether production technology file, bath manufacturing records be complete, confirms to meet the requirements.
By batch production instruction order, get imperial Fructus Jujubae capsule dried cream powder, crude drug powder, Radix Angelicae Sinensis volatile oil, Rhizoma Acori Graminei volatile oil from storehouse, check the name of an article in kind and quantity, and confirm errorless.Accurately material is taken by " batching post standard operating procedure ".
total mixed
Check whether operation room has " production licence "; Whether the running of pelletizing machine, two-dimensional motion mixer is normal; Whether production technology file, bath manufacturing records be complete, confirms to meet the requirements.
Imperial Fructus Jujubae capsule crude drug powder is put into hopper, sprays into Radix Angelicae Sinensis volatile oil and Rhizoma Acori Graminei volatile oil, add in mixer after stirring, drop into the mixing of imperial Fructus Jujubae capsule extract powder simultaneously.Mixed once amount should be no more than 2/3rds of mixing tank total measurement (volume).Incorporation time 30 minutes, rotating speed is 15 turns/min.The medicated powder mixed is put in clean container for subsequent use.
capsule charge
Check whether operation room has " production licence "; Whether fully-automatic capsule filling machine, capsule polisher work well; Whether production technology file, bath manufacturing records be complete, confirms to meet the requirements.Get No. 0 gem bluebonnet lean type Capsules 610,000 from storehouse, deposit in supplementary material temporary between, per tour is got by use amount limitation; Intermediate products dragon Fructus Jujubae capsule mixed powder is got by per tour use amount limitation from intermediate station, checkout facility main frame send capsule plate, correct block, module, filling bar, whether contain powder cup specification consistent and should be corresponding with softgel shell specification to be filled, carry out adjustment by fully-automatic capsule filling machine standard operating procedure to each position to install, in capsule hopper, add appropriate Capsules, then add a certain amount of attal in spice bucket.On capsule filler filling be every dress 0.5g(0.460g ~ 0.540g) capsule.At interval of 5 ~ 10 minutes, detect primary filling amount, every 30 minutes records once, guarantee that product is in acceptability limit.The capsule that filling is good eliminates distortion, splits shell, the waste product such as trachoma, ghost.Load in cleaning bag after the capsule polishing good to filling, inside and outside addendum material card.End-of-job, shutdown, break main power, cleaning machine sections residual material.
bubble-cap subpackage
Check whether operation room has " production licence "; Whether blister packaging machine works well; Whether production technology file, bath manufacturing records be complete, confirms to meet the requirements.
Change according to triple effect phase printing list and print triple effect phase steel letters.Two people check institute's transpose head content should be consistent with production ordering triple effect phase content.Upper heating at 125-130 DEG C, lower heating 125-130 DEG C, heat-sealing temperature 175-180 DEG C.
Get capsule grain, aluminium foil 22.00kg, PVC stiff sheet 160.00kg from intermediate station, handle handing over procedure.Check delivery receitp and circulation card, check material card and the name of an article, specification, quantity, lot number, two people check errorless after can carry out next step operation.
Install hopper, and in hopper, add capsule grain, bring into operation, every plate packaging quantity is 12, and stamping-out speed is: 30-40 time/min.Produce aluminium-plastic panel to choose and pick up, qualified aluminium-plastic panel is put into transfer basket, defectively put into specified containers, answer regular check aluminium-plastic panel whether to conform with the regulations standard in production process, every two hours, sealing is inspected by random samples.After end-of-job, press " always stopping " key, out of service, closes compression gas, cooling water, cuts off main power.Produce and terminate, cut residue PVC, aluminium foil, and take quantity and enclose material and snap fits into cleaning bag, cancelling stocks cartonning is sealed up for safekeeping.
outer package
Check whether operation room has " production licence "; Whether there is the upper batch of material left over; Whether production technology file, bath manufacturing records be complete, confirms to meet the requirements.
To get material respectively in intermediate station, packaging material storehouse, standby box post, plastic packaging post according to packaging production ordering, product description, seal, triple effect phase print qualified packing box and packing crates, plastic packaging bag, jointly to check the name of an article of lead material and packaging material, volume (criticizing) number, packing specification, quantity etc. and production ordering and technological requirement consistent with intermediate station manager, standby box post director and warehouse keeper, handles handing over procedure of being correlated with simultaneously.Check packaging material outward appearance should totally, clean and tidy, Packing Intact, without breakage, is made moist, and damaged by rats is damaged by worms sign, can carry out neck and expect, lead material process to answer strict implement two people to check system after passed examination.
packaging operation
Description is got in queuing, and squad leader counts granting, and first operator should check the name of an article, specification.Browse inspection, check and be mixed into or without other key to variety book, and then folding, be the doubling of axle with broadside time folding, in folding process, defective work chosen, deposit in defective work collecting box.
Queue up according to squad leader's point sequence code and get packing box, packing crates.First check the concordance of the name of an article of box and case, specification, triple effect phase and sequence code, blend compounds band, by involution bottom packing crates, places one, backing plate in case, to put to operating board etc. to be packaged.Squad leader answers fixation to deposit after specifying special messenger that material is transported to operation room, and operator should check the name of an article, specification, triple effect phase again, then by material to table top, wait to be packaged.
Packaging starts, and first picks packing box, and without the need to rolling over box, pressing box card line, gets packaged medicated bag 1, description 1 loads in box, buckle well lid, load packing crates.Defective material is chosen by packaging process, deposits in defective work collecting box.FCL packaging is complete, is got togather by case lid, and block pattern row pattern, in appointment pallet, waits for plastic packaging.This batch of packing of product terminates, and hand over warehouse for finished product custody for account of customers, squad leader checks defective material quantity, registration quantity, after scrapping situation statistics, returns packaging material storehouse, handles corresponding entries.
This product is capsule, and content is the powder of brown color, gas delicate fragrance, bitter in the mouth.At tranquillizing and allaying excitement, pure and fresh resolving depression aspect effect is very good, is mainly used in the treatment of the insomnia caused by hyperactivity of heart-fire, the symptom such as vexed, dizzy.
Claims (2)
1. a medicine for the ill symptoms for the treatment of caused by hyperactivity of heart-fire, is characterized in that: formula is as follows:
Rhizoma Coptidis 150g Radix Scutellariae 150g Radix Puerariae 200g Radix Salviae Miltiorrhizae 200g
Radix Ginseng 50g Radix Angelicae Sinensis 200g Rhizoma Acori Graminei 200g Flos Albiziae 200g
Bulbus Lilii 100g Semen Ziziphi Spinosae 300g Os Draconis 250g Concha Ostreae 250g.
2. a method for the medicine of manufacturing claims 1, is characterized in that: comprise the following steps:
A, above 12 tastes, except Os Draconis, each 100g of Concha Ostreae are ground into except fine powder, get Radix Angelicae Sinensis, Rhizoma Acori Graminei etc. two taste add water that to extract volatile oil for subsequent use for 6-8 times amount respectively, the another device of the aqueous solution after distillation is collected;
B, get Rhizoma Coptidis, Radix Scutellariae, Radix Puerariae, Radix Salviae Miltiorrhizae, people participate in 70% ethanol 4 times amount reflux, extract, twice, three hours first times, second time two hours, filter, filter and merge, decompression recycling ethanol, being concentrated into relative density is 1.30(50 degree Celsius) thick paste;
C, get each 150g of Bulbus Lilii, Flos Albiziae, Semen Ziziphi Spinosae, Os Draconis and Concha Ostreae and said extracted volatile oil and alcohol reflux after merge with medicinal residues, 10 times amount that add water decoct secondary, each 1.5 hours, filter, filter and merge, add distillate, being concentrated into relative density is 1.30(50 degree Celsius) thick paste;
D, above-mentioned thick paste to be merged, dry, pulverize into fine powder;
E, volatile oil is sprayed in Os Draconis, Concha Ostreae fine powder, with above-mentioned medicated powder stirring and evenly mixing, sieves, incapsulate, make 1000, to obtain final product.
Priority Applications (1)
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CN201510399412.1A CN105031201A (en) | 2015-07-09 | 2015-07-09 | Medicament for treating bad symptoms caused by heart-fire hyperactivity and preparation method thereof |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105770378A (en) * | 2016-03-18 | 2016-07-20 | 陕西金象制药有限公司 | Ossa draconis and Semen ziziphi spinosae capsules and preparation method thereof |
CN110151875A (en) * | 2019-05-21 | 2019-08-23 | 陕西金象制药有限公司 | A kind of dragon jujube capsule and preparation method thereof |
-
2015
- 2015-07-09 CN CN201510399412.1A patent/CN105031201A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105770378A (en) * | 2016-03-18 | 2016-07-20 | 陕西金象制药有限公司 | Ossa draconis and Semen ziziphi spinosae capsules and preparation method thereof |
CN110151875A (en) * | 2019-05-21 | 2019-08-23 | 陕西金象制药有限公司 | A kind of dragon jujube capsule and preparation method thereof |
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