CN101697956B - Anti-acne jelly with pearl hydrolyzate liposome - Google Patents

Anti-acne jelly with pearl hydrolyzate liposome Download PDF

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Publication number
CN101697956B
CN101697956B CN200910205088XA CN200910205088A CN101697956B CN 101697956 B CN101697956 B CN 101697956B CN 200910205088X A CN200910205088X A CN 200910205088XA CN 200910205088 A CN200910205088 A CN 200910205088A CN 101697956 B CN101697956 B CN 101697956B
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skin
liposome
acne
pearl
cells
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CN101697956A (en
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周树立
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Hainan Jingrun Zhenzhu Biological Technology Co Ltd
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Hainan Jingrun Zhenzhu Biological Technology Co Ltd
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Abstract

The invention discloses an anti-acne jelly with pearl hydrolyzate liposome. Acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer, glycerol, 1,3-butanediol, witch-hazel extract, pearl hydrolyzate liposome, plant sterols, capryloyl glycin, allantoin, dipotassium glycyrrhizinate, diazolidinyl urea, methyl hydroxybenzoate, trolamine, disodium ethylene diamine tetraacetate and deionized water are evenly mixed to prepare the anti-acne jelly. In the invention, the pearl hydrolyzate liposome is added to the anti-acne jelly to effectively enhance the metabolism of skin cells, inhibit surplus lipid from secretion, dredge pores of skin cells, smoothly discharge impurities blocking the skin pores, such as dust, grease, bacteria, peeling, dead cells and the like, and promote the regeneration of surface cells, thereby effectively repairing impaired skin, accelerating the healing of impaired skin sores and pox marks, enabling the skin to be in a healthy state and smoothing the skin.

Description

A kind of anti-acne jelly that adds pearl hydrolysate liposome
Technical field
The present invention relates to a kind of cosmetics, be specifically related to a kind of anti-acne jelly that adds pearl hydrolysate liposome.
Background technology
Comedo, acne are one of modal skin problems, good sending out in vigorous positions of sebum secretion such as face, shirtfronts.It is because the pilosebaceous unit disease that combined factors effects such as hypersteatosis, pilosebaceous duct hyperkeratosis, propionibacterium acnes propagation cause.Raising along with people's living standard, everybody more and more pays close attention to the problem of comedo, this influence beauty treatment of acne, the ratio of seeking medical advice raises gradually, and anti-acne class skin care item also emerge in an endless stream, and product for resolving poxes in the market has soap class, cleaning solution, lotion, Emulsion, gel, cream frost etc.Because the formation of comedo is relevant with a variety of causes, the anti-acne skin care item are exactly to add different active component at these reasons in cosmetics, generally all be to sterilize earlier (thoroughly to kill the skin surface pathogenic bacterium, prevent that bacterial infection skin from making its inflammation), (can effectively control the variola of infection inflammation at short notice by antiinflammation again, acne, and it is disappeared gradually take off) etc. process reaches the anti-acne effect.Nowadays the product for resolving poxes on the market all is by means of medical outcome, adopt antibiotic or antibiotics material, as metronidazole, chloromycetin etc., add dexamethasone antiallergic and salicylic acid exfoliation again, these raw materials are effective really to anti-inflammation and sterilization, but it is particularly responsive to face skin that these raw materials all belong to antibiotic, antibiotics and hormone, and can not effectively repair the open sore part and the pox seal of damage, thereby can not fundamentally solve the practical problem of skin anti-acne.
Margarita is acknowledged as cosmetic good merchantable brand always, and its beauty treatment mechanism is aminoacid and the trace element that contains various needed by human body in the Margarita, and nutritional labeling that contains in the Margarita and the required nutrient of human skin are approaching, are easy to be absorbed by the body, and have the effect of aesthetic health care.Utilizing the effective ingredient of Margarita in the cosmetics at present mainly is to carry out with the form of Margarita hydrolyzed solution, owing to contain various trace elements in the Margarita, electrical conductivity is higher, as direct interpolation, be easy to destroy the system of cosmetics, and Margarita hydrolyzed solution added directly to its effective ingredient is easy to be destroyed by other components in the cosmetics, it is lost activity and be difficult to be absorbed by the body.
Patent " CN1795874A " discloses a kind of method for preparing pearl hydrolysate liposome, it is that Margarita hydrolyzed solution is dissolved in the phosphate buffer, transfer pH value to neutral, slowly join then in the bottle of making by the soybean lecithin dry film, obtain pearl hydrolysate liposome through vibration, ultrasonic Treatment.The pearl hydrolysate liposome that prepared by this method has removed calcium carbonate a large amount of in the Margarita powder; reduce the conductivity of hydrolyzed solution; minimizing protects the effective ingredient of Margarita not destroyed by other components to the destruction of cosmetics series effectively, has improved the assimilation effect of Margarita greatly.
Summary of the invention
The objective of the invention is provides a kind of anti-acne jelly that adds pearl hydrolysate liposome at the deficiencies in the prior art, it can improve keratodermatitis, efficient bacteriostasis and sterilization intelligent balance oils and fats, make skin be in health status, effectively dispel comedo, acne and the impaired skin of energy maintenance, making the smooth exquisiteness of skin, is a kind of safe, natural anti-acne active matter that efficient is high.
Another object of the present invention provides a kind of preparation method of above-mentioned anti-acne jelly.
The technical solution adopted in the present invention is:
A kind of anti-acne jelly that adds pearl hydrolysate liposome, be by acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross linked polymer, glycerol, 1, the 3-butanediol, the Radix Hamamelidis Mollis extract, pearl hydrolysate liposome, phytosterol, the decoyl glycine, allantoin, glycyrrhizic acid dipotassium, two imidazolidinyl urea, methyl hydroxybenzoate, triethanolamine, disodiumedetate and deionized water are prepared from through mix homogeneously, wherein each components contents is respectively by weight percentage: acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross linked polymer 0.3~0.8%, glycerol 2.0~5.0%, 1,3-butanediol 2.0~5.0%, Radix Hamamelidis Mollis extract 2.0~5.0%, pearl hydrolysate liposome 3.0~8.0%, phytosterol 1.0~5.0%, decoyl glycine 0.2~1.0%, allantoin 0.1~0.2%, glycyrrhizic acid dipotassium 0.1~0.4%, two imidazolidinyl urea 0.1~0.5%, methyl hydroxybenzoate 0.1~0.2%, triethanolamine 0.5~1.0%, disodiumedetate 0.05~0.15%, surplus are deionized water.
A kind of preparation method of anti-acne jelly of above-mentioned interpolation pearl hydrolysate liposome, its processing step is as follows:
1, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross linked polymer soaks glycerol adding after 0.5~1.5 hour, 1,3 butylene glycol, Radix Hamamelidis Mollis extract, allantoin, methyl hydroxybenzoate, disodiumedetate with deionized water and mixes and drop into the emulsifying pot and be heated with stirring to 80~85 ℃; Keep the vacuum and the constantly degassing, until transparent no steam bubble;
2, adding triethanolamine 80~85 ℃ the time stirs;
3, being cooled to 40~50 ℃ adds the discharging that stirs of pearl hydrolysate liposome, phytosterol, decoyl glycine, two imidazolidinyl urea and obtains finished product.
For understanding the result of use of this product, form with questionnaire survey has been carried out investigation on probation widely in China to this product, men and women's property trier 100 people in all parts of the country are included in this investigation altogether in, male 21 people wherein, women 79 people, the oldest 39 years old, minimum 16 years old, about 25 years old mean age, regain 95 parts of effective questionnaires altogether.
95 triers use 4 week of the anti-acne jelly back of interpolation pearl hydrolysate liposome as follows to the result of " small pox " relevant every index improvement degree self evaluation:
The skin oil and fat secretion has 65% and 23.8% trier to have moderate to improve and obviously improve respectively;
Blackhead has 75% and 9.38% trier to have moderate to improve and obviously improve respectively;
Hoary hair's acne have 31.25% and 58.13% trier to have moderate to improve and obviously improve respectively;
The inflammatory pimple has 47.25% and 28.13% trier to have moderate to improve and obviously improve respectively;
The pus born of the same parents have 55.13% and 31.25% trier to have moderate to improve and obviously improve respectively.
From the result of trier's self assessment as can be seen, this product has in various degree improvement to skin oil and fat secretion, acne, inflammation pimple and pustule.
Show according to survey result: the anti-acne jelly of this interpolation pearl hydrolysate liposome has preferably " anti-acne " effect.
The present invention has added pearl hydrolysate liposome in anti-acne jelly, not only can bactericidal antiphlogistic, infection, dispel acne and skin sore, and can strengthen the skin cell metabolism function effectively, effectively suppress unnecessary fat secretion, mediation Skin Cell pore, impurity such as being blocked in the interior dust of skin pore, oil stain, antibacterial, decortication, dead cell is discharged smoothly, promote the regeneration of superficial cell, thereby effectively repaired impaired skin, the skin open sore part of healing acceleration damage and pox seal can make skin be in health status, make the smooth exquisiteness of skin.
The specific embodiment
The invention will be further described with non-limiting examples below.
Embodiment one
1, measures acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross linked polymer 0.4kg, glycerol 3.0kg, 1,3 butylene glycol 3.0kg, Radix Hamamelidis Mollis extract 3.0kg, pearl hydrolysate liposome 5.0kg, phytosterol 2.0kg, decoyl glycine 0.5kg, allantoin 0.15kg, glycyrrhizic acid dipotassium 0.2kg, two imidazolidinyl urea 0.2kg, methyl hydroxybenzoate 0.15kg, triethanolamine 0.5kg, disodiumedetate 0.05kg, ionized water 81.3kg by prescription.
2, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross linked polymer soaks glycerol adding after 1 hour, 1,3 butylene glycol, Radix Hamamelidis Mollis extract, allantoin, methyl hydroxybenzoate, disodiumedetate with deionized water and mixes and drop into the emulsifying pot and be heated with stirring to 85 ℃; Keep the vacuum and the constantly degassing, until transparent no steam bubble;
3, adding triethanolamine 85 ℃ the time stirs;
4, being cooled to 45 ℃ adds the discharging that stirs of pearl hydrolysate liposome, phytosterol, decoyl glycine, two imidazolidinyl urea and obtains finished product.
Embodiment two
1, measures acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross linked polymer 0.5kg, glycerol 4.0kg, 1,3 butylene glycol 5.0kg, Radix Hamamelidis Mollis extract 5.0kg, pearl hydrolysate liposome 8.0kg, phytosterol 1.0kg, decoyl glycine 0.2kg, allantoin 0.1kg, glycyrrhizic acid dipotassium 0.1kg, two imidazolidinyl urea 0.15kg, methyl hydroxybenzoate 0.1kg, triethanolamine 0.4kg, disodiumedetate 0.05kg, ionized water 75.4kg by prescription.
2, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross linked polymer soaks glycerol adding after 1 hour, 1,3 butylene glycol, Radix Hamamelidis Mollis extract, allantoin, methyl hydroxybenzoate, disodiumedetate with deionized water and mixes and drop into the emulsifying pot and be heated with stirring to 80 ℃; Keep the vacuum and the constantly degassing, until transparent no steam bubble;
3, adding triethanolamine 80 ℃ the time stirs;
4, being cooled to 50 ℃ adds the discharging that stirs of pearl hydrolysate liposome, phytosterol, decoyl glycine, two imidazolidinyl urea and obtains finished product.
Embodiment three
1, measures acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross linked polymer 1kg, glycerol 10.0kg, 1,3 butylene glycol 8.0kg, Radix Hamamelidis Mollis extract 8.0kg, pearl hydrolysate liposome 12.0kg, phytosterol 3kg, decoyl glycine 1kg, allantoin 0.4kg, glycyrrhizic acid dipotassium 0.3kg, two imidazolidinyl urea 0.4kg, methyl hydroxybenzoate 0.3kg, triethanolamine 0.8kg, disodiumedetate 0.1kg, ionized water 154.7kg by prescription.
2, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross linked polymer soaks glycerol adding after 1 hour, 1,3 butylene glycol, Radix Hamamelidis Mollis extract, allantoin, methyl hydroxybenzoate, disodiumedetate with deionized water and mixes and drop into the emulsifying pot and be heated with stirring to 83 ℃; Keep the vacuum and the constantly degassing, until transparent no steam bubble;
3, adding triethanolamine 83 ℃ the time stirs;
4, being cooled to 45 ℃ adds the discharging that stirs of pearl hydrolysate liposome, phytosterol, decoyl glycine, two imidazolidinyl urea and obtains finished product.

Claims (1)

1. anti-acne jelly that adds pearl hydrolysate liposome, it is characterized in that: be by acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross linked polymer, glycerol, 1, the 3-butanediol, the Radix Hamamelidis Mollis extract, pearl hydrolysate liposome, phytosterol, the decoyl glycine, allantoin, glycyrrhizic acid dipotassium, two imidazolidinyl urea, methyl hydroxybenzoate, triethanolamine, disodiumedetate and deionized water are prepared from through mix homogeneously, wherein each components contents is respectively by weight percentage: acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross linked polymer 0.3~0.8%, glycerol 2.0~5.0%, 1,3-butanediol 2.0~5.0%, Radix Hamamelidis Mollis extract 2.0~5.0%, pearl hydrolysate liposome 3.0~8.0%, phytosterol 1.0~5.0%, decoyl glycine 0.2~1.0%, allantoin 0.1~0.2%, glycyrrhizic acid dipotassium 0.1~0.4%, two imidazolidinyl urea 0.1~0.5%, methyl hydroxybenzoate 0.1~0.2%, triethanolamine 0.5~1.0%, disodiumedetate 0.05~0.15%, surplus are deionized water.
CN200910205088XA 2009-10-19 2009-10-19 Anti-acne jelly with pearl hydrolyzate liposome Active CN101697956B (en)

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CN102133169B (en) * 2011-03-22 2012-08-08 海南海之润生物工程有限公司 Cosmetic for protecting eye and preparation method thereof
CN102225040B (en) * 2011-06-08 2012-09-05 浙江欧诗漫集团有限公司 Pearl skin-caring oil-controlling essence
CN102198071B (en) * 2011-06-08 2012-11-28 浙江欧诗漫集团有限公司 Preparation process for pearl skin-care and oil-control essence
CN103230359B (en) * 2013-04-15 2014-11-19 北京华夏众芳生物科技有限公司 Skin-care composition having anti acne efficacy, mask and preparation method thereof
CN105147570B (en) * 2015-10-14 2017-12-15 皖南医学院 A kind of pore cleanser frosted white gel and preparation method thereof only
CN105267122B (en) * 2015-11-04 2018-06-26 皖南医学院 A kind of natural moisture preserving pore refining gel and preparation method thereof
CN105796461A (en) * 2016-03-21 2016-07-27 浙江大学 Moisturizing and repairing lotion containing hydrolyzed pearl essence flexible nano-liposomes and sea buckthron oil
CN108096378A (en) * 2017-12-26 2018-06-01 广州在路上信息科技有限公司 A kind of blemish clearing gel and preparation method thereof
CN109316438A (en) * 2018-08-30 2019-02-12 珀莱雅化妆品股份有限公司 A kind of preparation method of the solid precursor liposome with acne-removing
CN111973499A (en) * 2019-05-24 2020-11-24 西安博和医疗科技有限公司 Agent combination for skin care
CN115837002A (en) * 2022-09-28 2023-03-24 广州丝芬化妆品有限公司 Composition containing pearl extract and mother-of-pearl extract and application thereof

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CN101288640A (en) * 2008-05-23 2008-10-22 海南京润珍珠生物技术股份有限公司 Anti-acne essence added with pearl hydrolysate liposome
CN101450032A (en) * 2007-11-30 2009-06-10 北京化工大学 Rose whitening moisture-retention gel and preparation method thereof

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
CN101450032A (en) * 2007-11-30 2009-06-10 北京化工大学 Rose whitening moisture-retention gel and preparation method thereof
CN101288640A (en) * 2008-05-23 2008-10-22 海南京润珍珠生物技术股份有限公司 Anti-acne essence added with pearl hydrolysate liposome

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Denomination of invention: Anti-acne jelly with pearl hydrolyzate liposome

Effective date of registration: 20160518

Granted publication date: 20110810

Pledgee: Haikou rural commercial bank Limited by Share Ltd

Pledgor: Hainan Jingrun Zhenzhu Biological Technology Co., Ltd.

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Date of cancellation: 20200831

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Pledgee: Haikou rural commercial bank Limited by Share Ltd.

Pledgor: HAINAN JINGRUN PEARL BIOTECHNOLOGY Co.,Ltd.

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