CN101670155B - Digitalized high sound pressure ultrasound non-invasive therapy system - Google Patents
Digitalized high sound pressure ultrasound non-invasive therapy system Download PDFInfo
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- CN101670155B CN101670155B CN200910308407XA CN200910308407A CN101670155B CN 101670155 B CN101670155 B CN 101670155B CN 200910308407X A CN200910308407X A CN 200910308407XA CN 200910308407 A CN200910308407 A CN 200910308407A CN 101670155 B CN101670155 B CN 101670155B
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Abstract
The invention discloses a digitalization high sound pressure ultrasound non-invasive therapy system which comprises a power supply system (16), a display system (15), a combined type chip ultrasound therapy head (14), a work station control system (11), a digital pulse signal generator (12), and a high sound pressure digital pulse power amplifier (13), wherein the display system (15), the digital pulse signal generator (12), the high sound pressure digital pulse power amplifier (13), and the combined type chip ultrasound therapy head (14) are respectively connected with a work station control system (11); an output interface of the digital pulse signal generator (12) is connected with an input interface of the high sound pressure digital pulse power amplifier (13); an output interface of the high sound pressure digital pulse power amplifier (13) is connected with the input interface of the combined type chip ultrasound therapy head (14). The system can generate needed high sound pressure pulses according to therapy requirements.
Description
Technical field
The present invention relates to a kind of tumor treatment system and device, relate in particular to a kind of digitalization high sound pressure ultrasound non-invasive therapy system.
Background technology
Malignant tumor is the disease of serious threat human life health, and its treatment is the difficult point and the focus of medical circle always.At present, the basic skills of treatment cancer has therapies such as surgical resection, radiotherapy, chemotherapy and biological immune, but these treatment meanss often can not satisfy patient's treatment requirement, and there is a considerable shortcoming, easily produce severe complications and side effect, not only risk is big, and has reduced patient's life quality.
The surgical resection treatment, the surgical wound face is big, malignant tumor is extractd fully to be not easy especially, and postoperative is very big to the injury of human body.
Radiotherapy is to shine the effect that tumor reaches treatment with the lonizing radiation that radioactive material such as institutes such as radium, cobalt radiate out.Though reached the purpose of kill tumor cell, normal immunocyte also together has been killed.Because the destruction of lonizing radiation, patient's blood change, bone marrow human body sustain damage, leukocyte and thrombocytopenia, serious even cause septicemia, for example: cause stomatocace easily, atrophy of salivary gland, radiation pneumonia, hyperemia and edema even take place in xerostomia unbearably, and the damage of all these is likely lifelong participation.
Chemotherapy then is that " chemicals " injected in the body in order to poison cancerous cell with poison.This class chemicals is quite tangible to the damage of human body, in kill cancer cell, the human normal cell is brought serious damage equally.Cause the severe inhibition of hemopoietic function of bone marrow, seriously kill and wound intravital immunocyte, leukocyte, erythrocyte and hematoblastic serious reduction, immunity is very low, patient body quality extremely feeble, to the severe inhibition of gastrointestinal mucosa cell, serious strike digestive function.Obvious adverse reaction appears in gastrointestinal tract, the most outstanding performance of patient be feel sick, vomiting, inappetence etc.The all essential decomposition of all these medicines through internal organs.To some extent important organs such as liver, kidney are being brought infringement equally.In addition, put, chemotherapy also can cause alopecia, skin lesion etc., causes great pressure and influence for patients ' psychological, life.
In order to solve the deficiency of above Therapeutic Method, industry on Therapeutic Method also at other Therapeutic Method of the exploration of making great efforts.
The generation of entity tumor, development, invasion and attack and shift and rely on tumor-blood-vessel growth (Tumor angiogenesis) are so be that the tumor " dormancy therapy " of therapeutic purposes is in recent years continue a kind of new oncotherapy pattern of performing the operation, growing up behind the chemicotherapy with inhibition, thromboembolism or blocking-up tumor neogenetic blood vessels.At present, get involved the tremulous pulse that the blood vessel embolism therapy can only the big caliber of thromboembolism, powerless to collateral circulation; Use chemistry or biological preparation antineoplastic vascular to generate treatment and can directly act on tumor neovasculature target spot, but specificity is not high, curative effect is undesirable.Tumor naturopathy method comprises that various interventions are hot in naturely melted, freezing, electrochemistry etc., and all by puncture or operation direct killing tumor tissues, but side effect is also bigger.
The ultrasonic cavitation effect is meant that microbubble produces a series of dynamic processes such as concussion, expansion, contraction and implosion in the liquid under the ultrasound wave effect, and following extremely exergonic behaviors such as transient high temperature, high pressure, shock wave and jet is one of hyperacoustic biophysics effect.
Utilize ultrasonic energy non-invasive treatment tumor is the target that industry is pursued always.In recent years, the basic research of ultrasonic cavitation effect in atraumatic ultrasonic therapeutic field is very active, but most of correlational studyes relate generally to drug release and gene transfection, and be few to the mechanical injuries effect study that its cavitation produces.
The ultrasonic cavitation treatment need make mediation (microvesicle) produce transient cavitation at the ultrasonic pulse of mediation (microvesicle) the emission peak value negative pressure in the circulation of biological blood body, discharges high temperature, high pressure, shock wave, microjet homenergic form.For fear of the heat effect that produces similar HIFU, ultrasonic energy must be the form of energy of high sound pressure, the harmonic(-)mean sound intensity, low duty ratio.At present, do not see the ultrasonic energy mode that the special cavitation effect that produces for high sound pressure ultrasonication mediation (microvesicle) designs in the existing ultrasonic therapeutic apparatus, do not see the ultrasonic physics therapeutic instrument of special-purpose ultrasonic cavitation mediation (microvesicle) treatment and the ultrasonic energy form report of this device emission as yet.
Summary of the invention
The purpose of this invention is to provide a kind ofly, design a kind of atraumatic digitalization high sound pressure ultrasound pulse therapy system in order to overcome the above-mentioned shortcoming of conventional ultrasound treatment.
The objective of the invention is to be achieved through the following technical solutions:
One digitalization high sound pressure ultrasound non-invasive therapy system, comprise electric power system 16, display system 15, modular wafer ultrasonic therapeutic head 14 is characterized in that, also comprise work station control system 11, digital pulse signal generator 12, high sound pressure digit pulse power amplifier 13; Display system 15, digital pulse signal generator 12, high sound pressure digit pulse power amplifier 13, modular wafer ultrasonic therapeutic head 14 are connected with work station control system 11 respectively; The output interface of digital pulse signal generator 12 is connected with the input interface of high sound pressure digit pulse power amplifier 13; The output interface of high sound pressure digit pulse power amplifier 13 is connected with the input interface of modular wafer ultrasonic therapeutic head 14;
Work station control system 11: digit pulse signal generator 12, high sound pressure digit pulse power amplifier 13 are issued the control parameter command, and the information cue of output parameter, revise the control parameter that issues for the user at any time according to prompting;
Digital pulse signal generator 12: be used for the instruction that receiving workstation control system 11 is sent, instruction according to work station control system 11 produces a digital pulse signal, and to work station control system 11 feedback digital pulse signal generators 12 work at present states;
High sound pressure digit pulse power amplifier 13: the instruction that receiving workstation control system 11 is sent, keep accurately working asynchronously with digital pulse signal generator 12, feedback high sound pressure digit pulse power amplifier 13 work at present states, generate the high pressure pulses of therapeutic ultrasound, the high pressure pulses of therapeutic ultrasound is transferred to modular wafer ultrasonic therapeutic head 14.
Described digital pulse signal generator 12 comprises single-chip microcomputer, field programmable gate array and latch;
Single-chip microcomputer: finish man-machine data interaction by the workstation software interface, latch is issued control signal, field programmable gate array is configured, and will controls parameter and be issued to field programmable gate array, make field programmable gate array according to layout setting requirement work;
Field programmable gate array: after the control parameter that the reception single-chip microcomputer issues, finish date processing, computing, and output timing logical signal, the sequential logic signal sends to high sound pressure digit pulse power amplifier 13 by interface, feed back the work at present state simultaneously and to single-chip microcomputer, single-chip microcomputer sends to the work station control system with information.
Latch: receive the control signal of single-chip microcomputer, the data that needs are transmitted latch output.
Described control parameter comprises modulation system, modulation width, therapeutic modality, treatment time, output adjusting, beginning/time-out, stopped treatment.
Described high sound pressure digit pulse power amplifier 13 comprises pulse amplifier 131 and pulse power supply 132.
Described pulse power supply 132 is made up of solid-state relay, electromagnetic relay, rectifier bridge, filter regulator circuit, temperature control circuit;
Solid-state relay, electromagnetic relay are used for isolated controlling and select power input voltage;
Rectifier bridge is a DC voltage with the AC signal rectification;
Filter regulator circuit, the DC voltage that rectifier bridge is exported carries out filtering, voltage stabilizing, obtains pressing than galvanic current;
Temperature control circuit, the monitoring environment temperature starts heat abstractor when temperature surpasses setting value.
Described pulse amplifier 131 comprises coupling isolated part, prime amplifier section and power amplifying part;
Coupling isolated part: digital pulse signal generator 12 and high sound pressure digit pulse power amplifier 13 are carried out physical isolation;
The prime amplifier section: shaping and voltage amplification are carried out in the pulse to 12 emissions of digit pulse signal generator, promote power amplifying part work;
Power amplifying part: the pulse signal to the prime amplifier section under the support of pulse power supply 132 carries out power amplification.
The array element compound mode of described modular wafer ultrasonic therapeutic head 14 makes up control by work station control system 11.
The present invention is a kind of digitalization high sound pressure ultrasound non-invasive therapy system, produce the form of energy of the required high sound pressure of ultrasonic cavitation treatment, the harmonic(-)mean sound intensity, low duty ratio, penetrate the high sound pressure pulse by modular wafer treatment hair, tumor is carried out the high sound pressure ultrasonic therapeutic.
Description of drawings
The present invention will illustrate by example and with reference to the mode of accompanying drawing, wherein:
Fig. 1 is a systematic schematic diagram of the present invention.
Fig. 2 is the schematic diagram of digital pulse signal generator.
Fig. 3 is interface software control principle figure of the present invention.
Fig. 4 is an interface software control figure of the present invention;
Fig. 5 is the schematic diagram of pulse amplifier;
Fig. 6 a is the coupling separation principle figure of pulse amplifier;
Fig. 6 b is the prime amplification principle figure of pulse amplifier;
Fig. 6 c is the power amplification schematic diagram of pulse amplifier;
Fig. 7 is solid-state relay, the electromagnetic relay circuit diagram of pulse power supply;
Fig. 8 is the relay circuit figure of pulse power supply;
Fig. 9 a is the compound fan-shaped compound modes of many array elements of wafer;
Fig. 9 b is many array element multi-frequency plyability compound mode of wafer;
Fig. 9 c is the compound compound mode of many array element double frequency of wafer;
Fig. 9 d is that the many array elements of the diagnosis of wafer are launched compound compound mode;
Fig. 9 e is that compound compound mode is launched in the diagnosis of wafer;
Fig. 9 f is the compound compound mode of the frequency multiplication of wafer.
Wherein, 11 of Fig. 1 is the work station control system, and 12 is the digital pulse signal generator, 13 is high sound pressure digit pulse power amplifier, and 14 is the modular wafer ultrasonic therapeutic head, and 15 is display system, 16 is electric power system, and 131 is pulse amplifier, and 132 is pulse power supply.
The specific embodiment
Disclosed all features in this description, or the step in disclosed all methods or the process except mutually exclusive feature and/or step, all can make up by any way.
Disclosed arbitrary feature in this description (comprising any accessory claim, summary and accompanying drawing) is unless special narration all can be replaced by other equivalences or the alternative features with similar purpose.That is, unless special narration, each feature is an example in a series of equivalences or the similar characteristics.
Below in conjunction with accompanying drawing the present invention is described in detail.
One digitalization high sound pressure ultrasound non-invasive therapy system, comprise electric power system 16, display system 15, modular wafer ultrasonic therapeutic head 14 is characterized in that, also comprise work station control system 11, digital pulse signal generator 12, high sound pressure digit pulse power amplifier 13; Display system 15, digital pulse signal generator 12, high sound pressure digit pulse power amplifier 13, modular wafer ultrasonic therapeutic head 14 are connected with the work station control system respectively; The output interface of digital pulse signal generator 12 is connected with the input interface of high sound pressure digit pulse power amplifier 13; The output interface of high sound pressure digit pulse power amplifier 13 is connected with the input interface of modular wafer ultrasonic therapeutic head 14;
A kind of digitalization high sound pressure ultrasound non-invasive therapy system, whole system is to be the center with work station control system 11, parameters such as the tranmitting frequency of control figure pulse signal generator 12, radiation pattern, launch time, startup, time-out, termination, the working method of control high sound pressure digit pulse power amplifier 13, the various combination mode of control ultrasonic therapeutic head wafer realizes whole technique effect.The principle of work station control system 11, digital pulse signal generator 12, high sound pressure digit pulse power amplifier 13, modular wafer treatment 14 is formed and is acted on as follows:
1, the digital pulse signal generator 12: digital pulse signal generator 12 is used for the instruction that receiving workstation control system 11 is sent, produce the digital pulse signal of a high accuracy, highly reliable, high stable by programming software, and to receiving workstation control system 11 timely feedback digital pulse signal generator 12 work at present states.
Digital pulse signal generator 12 mainly comprises single-chip microcomputer (MCU), field programmable gate array (FPGA) chip, latch, as shown in Figure 2; In therapy system, key is that launch parameters such as hyperacoustic tranmitting frequency, launch time, pulse width are controlled, and the ultrasound wave that is produced is determining the efficient of ultrasonic cavitation, also the success rate of decision treatment.So therapeutic equipment is very high to the digit pulse control functional requirement of signal generator; FPGA(Field Programmable Gate Array field programmable gate array) be the product that on the basis of programming devices such as PAL, GAL, PLD, further develops, be the highest a kind of of integrated level in the special IC (ASIC), advantages such as FPGA has that speed is fast, flexible configuration, secondary development are easy are so the present invention adopts the technical scheme of single-chip microcomputer (MCU)+FPGA to realize digit pulse signal generator 12 is carried out particular design.
The operation principle of digital pulse signal generator 12:
Single-chip microcomputer (MCU) is finished man-machine data interaction by the workstation software interface, disposes FPGA simultaneously and makes its work, will control parameter and be issued to FPGA and make it according to layout setting requirement work; After FPGA receives the control parameter, finish date processing, computing and export corresponding sequential logic signal, the sequential logic signal sends to high sound pressure digit pulse power amplifier 13 by interface, to single-chip microcomputer (MCU) feedback digital pulse signal generator 12 work at present states, single-chip microcomputer (MCU) sends to the work station control system with information and finally shows intuitively on the screen of display system 15 simultaneously.Concrete implementation is:
As shown in Figure 3, single-chip microcomputer (MCU) communicates by the serial ports workstation software, the control parameter of receiving workstation software, and by parameter control FPGA work, I/O port by FPGA sends digital pulse signal to excess sound pressure digit pulse power amplifier 13, and receives some work at present status informations of FPGA feedback and state is sent to work station control system and demonstration by single-chip microcomputer (MCU).
Workstation software comprises to the control parameter that single-chip microcomputer (MCU) sends: modulation system, modulation width, therapeutic modality, treatment time, output adjusting, beginning/time-out, stopped treatment.
The control parameter that the panel control end does not directly send to single-chip microcomputer (MCU), but send the control parameter to workstation software, finally will control parameter and send to single-chip microcomputer (MCU) by workstation software.
Single-chip microcomputer (MCU) is as follows with the rule of communication of interface software:
Use serial communication, workstation software sends instruction to single-chip microcomputer (MCU), and single-chip microcomputer (MCU) will be to carrying out CRC check and the byte number that obtains being postbacked to workstation software to guarantee reliable communications after receiving the data of interface software.
Single-chip microcomputer (MCU) will be controlled parameter and send to FPGA by the I/O mouth after receiving the effective order of workstation software, data/address bus, FPGA produces required pulse signal and exports latch to according to the data that obtain, finally by the output of single-chip microcomputer (MCU) control latch.
FPGA produces required frequency by the internal processes counting, and the order of sending according to single-chip microcomputer (MCU) simultaneously produces control signal, thereby forms required final composite pulse signal and deliver to power amplifier work.
It is as follows that the signal of FPGA produces principle:
FPGA receives only 4 supplemental characteristics: output adjusting, modulation width, modulation system, therapeutic modality; Treatment time is by single-chip microcomputer (MCU) control latch output and by realizing.
The data communication rule of FPGA and single-chip microcomputer (MCU) is as follows: write logic clock signal and data in the address and write the rising edge FPGA of logic clock signal and read address and the data that MCU delivers to the I/O mouth, according to receiving that data produce corresponding pulse signal and control signal is delivered to latch, wait single-chip microcomputer (MCU) unlatching latch then signal is delivered to high sound pressure digit pulse power amplifier 13.Concrete data communication rule is as follows:
Single-chip microcomputer (MCU) is respectively address and corresponding data to the instruction that FPGA sends.The address is used to export the identification of adjusting, modulation width, modulation system, 4 parameters of therapeutic modality, and data are then represented the sizes values of this address correspondence, and FPGA produces corresponding pulse signal and control signal according to the size of data.
Adopt single-chip microcomputer (MCU) to add synthetic realization of digitized of FPGA structure, have able to programme, reliability, good stability, frequency accuracy height, digital controlled signal source that capacity of resisting disturbance is strong, satisfy the requirement of equipment paired pulses, raising equipment integral body can high property.Also reserve simultaneously the interface of secondary development expansion.
Digital pulse signal generator 12 is under 11 controls of work station control system, issue control parameter commands such as tranmitting frequency, launch time, pulse width by 11 controls of work station control system, digital pulse signal generator 12 corresponding control commands, the dutycycle of generation is adjustable in 0.01%～20%.
2, the work station control system 11: digit pulse signal generator (12), high sound pressure digit pulse power amplifier (13) are issued the control parameter command, and the information cue of output parameter, revise the control parameter that issues for the user at any time according to prompting;
Whole therapy system is platform with the computer, carries out control mode work with workstation software, has abundant friendly human-computer interaction interface.
Can issue pulse control parameter, treatment time parameter by touch screen, output parameter is given digital pulse signal generator and impulse-type output amplifier, the custom of considering the user simultaneously keeps that the button method issues pulse control parameter, treatment time parameter, output parameter digital pulse signal generator is given impulse-type output amplifier, feedback digital pulse signal generator and impulse-type output amplifier work at present state guarantee that equipment work is controlled, reliable simultaneously; Simultaneously, can be by the array element compound mode of touch screen or keyboard input modular wafer ultrasonic therapeutic head 14; Modulation system, modulation width, therapeutic modality, treatment time, output are regulated control parameters such as (acoustic pressures) and are imported by the user.
Design has the information cue of hommization and reflects the situation of digital pulse signal generator 12 and 13 work of high sound pressure digit pulse amplifier, display system Set For Current parameter and treatment time and not treatment time point out the user, as shown in Figure 4.
Have abundant user to be provided with, the user can be provided with functions such as background, time prompting according to personal habits.
Workstation software is the control core of whole system, the modulation system of the pulse signal that control figure signal generator 12 is produced, modulating time, therapeutic modality, treatment time, startup, time-out, termination, acoustic pressure size and high sound pressure digit pulse amplifier 13.
3, high sound pressure digit pulse power amplifier 13: the instruction that receiving workstation control system 11 is sent, keep accurately working asynchronously with digital pulse signal generator 12, in time feedback pulse out amplifier work at present state provides treatment needed ultrasonic acoustic pressure, reaches therapeutic purposes.
High sound pressure digit pulse power amplifier 13 is a kind of special amplifier circuits.Adopt the coupling of photoelectricity isolation method, be characterized in that safety is good, anti-interference strong, can export the pulsed ultrasonic wave of microsecond level, realize peak sound pressure (comprising peak negative pressure and peak value malleation) scalable, output average sound intensity scalable; Have efficient height, bandwidth, a plurality of resonance point, adapt to the characteristics of second harmonic, impulse wave, sawtooth waveforms.Adaptation has low in energy consumption under different frequencies, the efficient height, and heat energy hangs down characteristics, guarantees high-speed dedicated numerical control ultrasonic pulse circuit energy long-term stable operation, obtains best power output, reaches ideal therapeutic effect.
High sound pressure digit pulse power amplifier 13 comprises pulse amplifier 131 and pulse power supply 132.
Pulse amplifier 131: the coupling isolated part, shown in Fig. 6 a, purpose is that digital signal pulse generator (12) and high sound pressure digit pulse power amplifier (13) are carried out physical isolation; Working stability is guaranteed in interference between reducing mutually; The prime amplifier section, the pre-amplifier shown in Fig. 6 b that Q1, Q2, Q3 form, paired pulses has the function of shaping, voltage amplification, guarantees to promote power stage work; Power amplifying part shown in Fig. 6 c, is formed power output by power amplifier module, and the pulse signal to the prime amplifier section under the support of pulse power supply 132 carries out power amplification.
Pulse power supply 132: solid-state relay, electromagnetic relay are used to select power input voltage; Rectifier bridge is a DC voltage with the AC signal rectification; Filter regulator circuit carries out filtering, voltage stabilizing to the pulsating direct current of rectifier bridge output, obtains pressing than galvanic current; Temperature control circuit, the monitoring environment temperature starts the radiator fan heat radiation, for power supply provides good working environment when temperature is too high.
4, combination type crystal ultrasonic therapeutic head 14: modular wafer ultrasonic therapeutic head 14 is the control circuit control emission wafer combination working methods by work station control system 11, perhaps intermittent pulse type ultrasound emission, the emission wafer is focus type or plane ultrasonic transducer, and optional frequency is formed ultrasonic therapeutic head at the wafer of any Frequency point of 0.2MHz～2MHz ± 20% or multi-frequency point.For example: the ultrasonic therapeutic head of 0.2 MHz, 0.5MHz, 1MHz, 2MHz etc., reach the needed working method of treatment different parts, being implemented in has multiple radiation pattern optional on the ultrasonic transducer, and user friendly operation improves therapeutic efficiency.
High sound pressure ultrasound non-invasive therapy device treatment head wafer compound mode has:
Compound mode one shown in Fig. 9 a, is the compound fan type of the many array elements combination type of wafer, and array element 1,2,3,4 is worked under same tranmitting frequency, can encourage 1,2,3,4 array element work respectively; Array element 1,2,3,4 can be with the single or multiple array elements of different compound modes alternately or work simultaneously.For example, can be that array element 1, array element 2, array element 3, array element 4 work independently respectively, also can carry out work or alternation with any compound mode, or four array elements are worked simultaneously with any two array elements or any three array elements.
Compound mode two shown in Fig. 9 b, is the compound compound mode of many array element multi-frequency, can encourage array element 1,2,3,4,5 transmitted pulses respectively under 5 tranmitting frequencies; Array element 1,2,3,4,5 replaces with the single or multiple array elements of different compound modes or works simultaneously.
Compound mode three shown in Fig. 9 c, is the compound compound mode of many array element double frequency, and two kinds of tranmitting frequencies encourage 1,2,3,4,5 array elements respectively in the various combination mode.1,2,3,4,5 array elements replace with the single or multiple array elements of different compound modes or work simultaneously.
Compound mode four shown in Fig. 9 d, is launched compound compound mode for diagnosing many array elements, and the 5th, the diagnosis head, array element 1,2,3,4 replaces with the single or multiple array elements of different compound modes or works simultaneously.For example, can be that array element 1, array element 2, array element 3, array element 4 work independently respectively, also can carry out work or alternation with any compound mode, or four array elements are worked simultaneously with any two array elements or any three array elements.
Compound mode five, shown in Fig. 9 e, be the compound compound mode of diagnosis emission, the 1st, emitting treatment array element, the 2nd, the diagnosis head, work in an alternating manner, promptly the diagnosis of the work of treatment array element 1 and diagnostic device 2 quits work in the time of treatment, on the contrary the diagnosis of diagnostic device 2 work and treatment array element 1 quits work in the time of diagnosis.
Compound mode six is the compound compound mode of frequency multiplication as Fig. 9 f, and array element 1 is emission array element, the 2nd, and the frequency multiplication emission array element of array element 1 tranmitting frequency, mode work or compound mode replace or work simultaneously separately.
The present invention is not limited to the aforesaid specific embodiment.The present invention expands to any new feature or any new combination that discloses in this manual, and the arbitrary new method that discloses or step or any new combination of process.
Claims (1)
1. digitalization high sound pressure ultrasound non-invasive therapy system, comprise electric power system (16), display system (15), modular wafer ultrasonic therapeutic head (14), it is characterized in that, also comprise work station control system (11), digital pulse signal generator (12), high sound pressure digit pulse power amplifier (13); Display system (15), digital pulse signal generator (12), high sound pressure digit pulse power amplifier (13), modular wafer ultrasonic therapeutic head (14) are connected with work station control system (11) respectively; The output interface of digital pulse signal generator (12) is connected with the input interface of high sound pressure digit pulse power amplifier (13); The output interface of high sound pressure digit pulse power amplifier (13) is connected with the input interface of modular wafer ultrasonic therapeutic head (14);
Work station control system (11): digit pulse signal generator (12), high sound pressure digit pulse power amplifier (13) are issued the control parameter command, and the information cue of output parameter, the user revises the control parameter that issues at any time according to prompting;
Digital pulse signal generator (12): be used for the instruction that receiving workstation control system (11) is sent, instruction according to work station control system (11) produces a digital pulse signal, and to work station control system (11) feedback digital pulse signal generator (12) work at present state;
High sound pressure digit pulse power amplifier (13): the instruction that receiving workstation control system (11) is sent, keep accurately working asynchronously with digital pulse signal generator (12), output high pressure pulses of therapeutic ultrasound, send the high pressure pulses of therapeutic ultrasound to modular wafer ultrasonic therapeutic head (14), and feedback high sound pressure digit pulse power amplifier (13) work at present state.
2.System according to claim 1 is characterized in that, described digital pulse signal generator (12) comprises single-chip microcomputer, field programmable gate array and latch;
Single-chip microcomputer: finish man-machine data interaction by the workstation software interface, issue control signal to latch, field programmable gate array is configured, and will control parameter and be issued to field programmable gate array, make field programmable gate array require work according to workstation software setting;
Field programmable gate array: after the control parameter that the reception single-chip microcomputer issues, finish date processing, computing, and output timing logical signal, the sequential logic signal sends to high sound pressure digit pulse power amplifier (13) by interface, feed back the work at present state simultaneously and to single-chip microcomputer, single-chip microcomputer sends to the work station control system with information;
Latch: receive the control signal of single-chip microcomputer, the data that needs are transmitted latch output.
3.System according to claim 1 and 2 is characterized in that, described control parameter comprises modulation system, modulation width, therapeutic modality, treatment time, output adjusting, beginning/time-out, stopped treatment.
4.System according to claim 2 is characterized in that, described high sound pressure digit pulse power amplifier (13) comprises pulse amplifier (131) and pulse power supply (132).
5.System according to claim 4 is characterized in that, described pulse power supply (132) comprises solid-state relay, electromagnetic relay, rectifier bridge, filter regulator circuit, temperature control circuit;
Solid-state relay, electromagnetic relay are used for isolated controlling and select power input voltage;
Rectifier bridge is a DC voltage with the AC signal rectification;
Filter regulator circuit, the DC voltage that rectifier bridge is exported carries out filtering, voltage stabilizing, obtains pressing than galvanic current;
Temperature control circuit, the monitoring environment temperature starts heat abstractor when temperature surpasses setting value.
6.System according to claim 4 is characterized in that, described pulse amplifier (131) comprises coupling isolated part, prime amplifier section and power amplifying part;
Coupling isolated part: digital pulse signal generator (12) and high sound pressure digit pulse power amplifier (13) are carried out physical isolation;
The prime amplifier section: shaping and voltage amplification are carried out in the pulse to digit pulse signal generator (12) emission, promote power amplifying part work;
Power amplifying part: the pulse signal to the prime amplifier section under the support of pulse power supply (132) carries out power amplification.
7.System according to claim 1 is characterized in that, the array element compound mode of described modular wafer ultrasonic therapeutic head (14) makes up control by work station control system (11).
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| CN102049109A (en) * | 2011-01-06 | 2011-05-11 | 西安交通大学 | Method for compensating flow heat loss by utilizing additional heat generated through flow microbubble cavitation in focused ultrasound field |
| CN102430212B (en) * | 2011-11-29 | 2014-12-24 | 绵阳索尼克电子有限责任公司 | Ultrasonic device for treating pains |
| CN107648751B (en) * | 2017-08-15 | 2024-06-04 | 安隽医疗科技(南京)有限公司 | Multifunctional intelligent informationized ultrasonic physiotherapy instrument |
| CN108144199A (en) * | 2017-12-22 | 2018-06-12 | 深圳先进技术研究院 | Device, method and system are motivated by ultrasound |
| CN107913477B (en) * | 2017-12-26 | 2020-04-10 | 中科绿谷（深圳）医疗科技有限公司 | Excitation method, device, equipment and storage medium of array ultrasonic transducer |
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