CN205698888U - A kind of ultrasonic conductivity meter - Google Patents
A kind of ultrasonic conductivity meter Download PDFInfo
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- CN205698888U CN205698888U CN201620249952.1U CN201620249952U CN205698888U CN 205698888 U CN205698888 U CN 205698888U CN 201620249952 U CN201620249952 U CN 201620249952U CN 205698888 U CN205698888 U CN 205698888U
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Abstract
The utility model discloses a kind of ultrasonic conductivity meter, including power supply, transformator, mainboard, display operation panel and treatment head, described power supply, transformator, mainboard, display panel are sequentially connected electrically, treatment head electrically connects with mainboard, it is characterized in that, mainboard includes that ultrasonic module, pulse control module, single-chip microcomputer main control module and over-current detection module, treatment head include ultrasonic transducer, electrode and shell.This utility model can realize ultrasonic target position and accurately offer medicine, it is possible to carry out the accurate manipulation of Drug therapy according to the situation of patient.
Description
Technical field
This utility model belongs to art of pharmacy, the ultrasonic conductivity meter of a kind of percutaneous dosing.
Background technology
It is a kind of with physical energy as power that ultrasonic medicinal penetrates, and makes medicine pass through intact skin and then enter people
Body circulation and pathological tissues play a kind of new dosage form and the practice of pharmacy of Drug therapy effect, it is achieved medicine
Target position transmission, the medical skill of precisely dispensing, have many and be better than the oral and feature of drug administration by injection method.
Ultrasonic conductivity meter is a kind of with ultrasound wave as major impetus, it is achieved the Needleless injection target position transdermal of medicine
Electromedical equipment. comprehensive employing intrasonic is ultrasonic waits physical energy, utilizes the radiation pressure of ultrasound wave to produce punching
Hitting power, making changes mechanical energy is strength kinetic energy, is launched by medicine and enters internal through skin, reaches needleless note
The effect penetrated. ultrasonic medicinal penetrates and directly medicine is delivered to pathological tissues, it is possible to achieve target position is accurately controlled
Treat；Medicine directly plays a role without systemic blood circulation, it is possible to reduce medicine normal tissue is particularly
The infringement of Liver and kidney organ；Without medicine arrive loss before target tissue (if medicine is at the first pass effect of liver,
With medicine ineffective distribution of other normal structures outside blood circulation target tissue), improve the biological profit of medicine
Expenditure, safely and effectively.
Ultrasonic transdermal technology is a kind of Novel medicine feeding method in recent years occurred, it has also become international the world of medicine is the most popular
Subdiscipline. ultrasonic conductivity meter realizes the instrument and equipment of ultrasonic transdermal, has obtained certain at clinical medicine
Application, has played good clinical treatment effect.Clinical practice shows, existing ultrasonic conductivity meter exists defeated
Go out that parameter is unstable, parameter waveform is nonstandard, easily disturbed by external voltage, electromagnetic modification, it is impossible to be complete
Meet the requirement of international telecommunication product safety standard, the even output risk damaged out of control.Therefore
Optimize the design of ultrasonic conductivity meter, compositions of adjusting the product mix, parameters optimization with realize circuit, be gesture must
OK.
Utility model content
In order to solve the problems referred to above, this utility model provides a kind of ultrasonic conductivity meter, including power supply, transformation
Device, mainboard, display operation panel and treatment head, described power supply, transformator, mainboard, display panel are electrically connected successively
Connect, treatment head electrically connect with mainboard, it is characterised in that mainboard include ultrasonic module, pulse control module,
Single-chip microcomputer main control module and over-current detection module, treatment head includes ultrasonic transducer, electrode and shell, wherein,
Described ultrasonic module includes self-oscillation circuit, ultrasonic exciting current modulating circuit, single-chip microcomputer master control
The control signal that module sends is by ultrasonic exciting current modulating circuit modulated sinusoid and produces ultrasonic action
Signal, this signal is amplified, and is just produced by self-maintained circuit by ultrasonic exciting current amplification circuit
After string ripple, treatment head is given in output；
Described pulse control module includes pulse signal generating unit, amplifying unit and modulating unit, pulse control
Molding block for receiving the control signal that single-chip microcomputer main control module sends, produce multiple pulse wave group output to
Treatment head；
Described single-chip microcomputer main control module, for receiving the parameter signal of display operation panel output, and according to this ginseng
Number signal output control signal controls described ultrasonic module and pulse control module；Described over-current detection module connects
Receive the control signal that single-chip microcomputer main control module sends, with reference to the electric current for the treatment of head feedback, control Pulse Width Control mould
The electric current of block output is strong and weak；
Described display operation panel includes parameter set unit and guidance panel, sends for arranging command signal
To single-chip microcomputer main control module, and show order parameter and the duty for the treatment of head of setting；
Further, described ultrasonic transducer includes inductance, resistance, piezoelectric ceramic piece.
Further, described self-oscillation circuit includes audion U6, audion U7 and auxiliary circuit, audion
U6 and audion U7 is connected in auxiliary circuit then in parallel.
Further, described ultrasonic exciting current modulating circuit includes audion Q5, audion Q6, audion
U5, resistance and diode D1001, audion Q5, audion Q6, audion U5, resistance and diode D1001
Electrical connection；The sine wave that ultrasonic exciting current-modulation electricity produces for modulating self-maintained circuit obtains ultrasonic
Excitation control signal.
Further, described single-chip microcomputer main control module is made up of single-chip microcomputer and peripheral circuit, and peripheral circuit includes crystalline substance
Shake and electric capacity.
Further, described over-current detection module includes negative feedback voltage amplifier and pin.
The beneficial effects of the utility model are:
The ultrasonic conductivity meter of one that the utility model proposes, can realize ultrasonic target position and accurately offer medicine, it is possible to according to
The situation of patient carries out the accurate manipulation of Drug therapy.Ultrasound wave passes through its radiation pressure and cavitation effect, changes
Putting in order of cell membrane and tissue film's lipid conformation, has opened tissue barrier, increases the logical of skin and tissue
Property thoroughly, enters the internal kinetic energy that provides for medicine, promotes that medicine is to internal transmission and transhipment. and can be in deep
Pathological tissues forms high drug concentration to be assembled, thus improves the bioavailability of medicine, improves the treatment of medicine
Effect；Penetrating Drug therapy with ultrasound wave local and can avoid the untoward reaction of systemic administration, drug effect remains long, is
Important breakthrough to convenient administration idea.
Accompanying drawing explanation
Fig. 1 is this utility model structural representation；
Fig. 2 is this utility model ultrasonic module circuit diagram；
Fig. 3 is this utility model pulse control module circuit diagram；
Fig. 4 is single-chip microcomputer main control module circuit diagram of the present utility model；
Fig. 5 is over-current detection module circuit diagram of the present utility model；
Fig. 6 is preceding pulse output waveform figure；
Fig. 7 is modulation pulsating wave output waveform figure；
Fig. 8 is preceding pulse and the modulation comprehensive output waveform figure of pulsating wave.
Detailed description of the invention
Below in conjunction with accompanying drawing, detailed description of the invention of the present utility model is described in detail.It is to be understood that
It is that detailed description of the invention described herein is merely to illustrate and explains this utility model, is not limited to
Enforcement of the present utility model.
A kind of ultrasonic conductivity meter, including power supply, transformator, mainboard, display operation panel and treatment head, described
Power supply, transformator, mainboard, display operation panel are sequentially connected electrically, and treatment head electrically connects with mainboard, mainboard bag
Including ultrasonic module, pulse control module, single-chip microcomputer main control module and over-current detection module, treatment head includes surpassing
Sonic transducer, electrode and shell.
As in figure 2 it is shown, ultrasonic module includes self-oscillation circuit, ultrasonic exciting current modulating circuit, from
Swash oscillating circuit and produce the sine wave that frequency is 1M Hz, through the control that single-chip microcomputer main control module circuit sends
Signal ULPWM controls the auxiliary of Q5, tri-audions of Q6, U5 and resistance R13-R17 and diode D1001 composition
Help circuit.The ultrasonic action that obtains after modulation, control signal, use the methods such as frequency modulation(PFM) to ultrasonic signal
Process, then formed oscillating circuit (mating with treatment head) by U6, U7 audion and relevant auxiliary circuit,
Obtain the driving signal matched with treatment head module.
As it is shown on figure 3, pulse control module includes pulse signal generating unit, amplifying unit (audion Q14)
And modulating unit, i.e. on-off circuit (audion Q15 and audion Q16), is used for receiving single-chip microcomputer master control mould
The control signal that block sends, produces multiple pulse wave group and exports to treatment head；TAP2K is by monolithic owner
The control signal that control modular circuit sends, this signal controls audion Q15 after being amplified by audion Q14 isolation,
The on-off circuit of audion Q16 composition, to 100HZ half-sinusoid signal processing, modulation, after being modulated,
To the pulse wave group of 2K frequency, pulse wave group number and the frequency of occurrences all can set according to parameter and control flexibly,
The impulse train signal of telecommunication, by treating head output, is responsible for dipole inversion at running repeat circuit K1.
Single-chip microcomputer main control module shows the parameter signal of operation panel output for receiving, and according to this parameter signal
Output control signal controls described ultrasonic module and pulse control module.As shown in Figure 4, single-chip microcomputer master control mould
Block by chip AT89C52 or other MCS-51 8 single-chip microcomputers of series and peripheral circuit (include Y1 crystal oscillator, C21,
C22 electric capacity etc.) composition, control the output part of whole instrument treatment, this module is man-machine by display panel
Interactive interface, obtains treatment parameter, and according to corresponding control signal such as above-mentioned parameter output ULPWM and TAP2K,
Control ultrasonic raw modular circuit and 2K pulse control module circuit, produce the signal of telecommunication needed.Over-current detection mould
Block receives the control signal that single-chip microcomputer main control module sends, and with reference to the electric current for the treatment of head feedback, controls pulse control
The electric current of molding block output is strong and weak.
As it is shown in figure 5, over-current detection module by amplifier U104LM324 and attached components and parts R3-R10, Q3,
D1 forms negative feedback voltage amplifier, single-chip microcomputer main control module provide pin IIC_0, the IIC_1 of signal,
IIC_2, IIC_3 are by the change (0,1) of each pin difference low and high level and be combined, the most right
According to the size by NET01 (network numbering, shown in Fig. 5) feedback current, change the electricity of U104A amplifier 2 foot
Pressure, dynamically adjusts, equal with U104A amplifier 3 foot voltage, reaches to control stream according to different body constitution and symptom
Cross the size purpose of body current.
Display operation panel includes parameter set unit and guidance panel, for being sent to list by arranging command signal
Sheet machine main control module, and show order parameter and the duty for the treatment of head of setting.Guidance panel by keyboard,
LED charactron, LED light forms, the internal parameter state arranged of LED numeral method machine, the time
Etc. information.The parameter state of LED instruction machine.Keyboard, as input equipment, inputs, adjusts the fortune of machine
Line parameter.
Treatment head is made up of ultrasonic transducer and match circuit, and wherein ultrasonic transducer is by piezoelectric ceramics
The compositions such as vibrating reed that sheet, metal are made, cabinet.It is limited by the manufacturing technical feature of piezoelectric ceramic piece,
The components and parts such as its electrical quantity often concordance is poor, needs to use inductance during use, resistance mate, so
Piezoelectric ceramic piece can be made to be operated in optimum Working, improve electric energy and be converted into the efficiency of mechanical energy, suppression is not
The heat needed produces.It addition, treatment head provides 2K pulse output interface, two metal vibrating plates are defeated
Two electrodes gone out.
Power module is changer, produces the power supply needed for main circuit board and tune by rectification or rectifying and wave-filtering
Basic steamed bread waveform needed for pulsating wave processed.2K pulse control module produces modulation pulsating wave and ultrasonic mould
Block drives ultrasonic transducer to be converted to ultrasound wave and jointly acts on human body.Modulation pulsating wave signal and ultrasound wave
By the treatment head comprehensive function of ultrasonic electric training on human body, human tissue cell can be made to separate and form hole
Gap, medicine can arrive patient part under the driving of ultrasound wave smoothly.This intercellular hole opening is
Temporary transient, after about 12 hours, hole will progressively close off and recover normal.
It is 0～87V adjustable preceding pulse that pulse control module needs to export VCC2K according to control, ultrasonic
The modulation pulsating wave that module output 100Hz half-sinusoid exports through ovennodulation.Fig. 6 is preceding pulse output wave
Shape, Fig. 7 is modulation pulsating wave output waveform.Fig. 8 is preceding pulse and the modulation comprehensive output waveform of pulsating wave.
All signal waveforms have the requirement of strict sequential and shape, and error is less than 10%.
A kind of ultrasound-transmissive method of ultrasonic conductivity meter, step 1: pulse control module and single-chip microcomputer master control
Pulse wave group after resume module, repeatedly acts on human body through described treatment head through medium；Pulse wave group
Including preceding pulse, preceding pulse is constituted one group by the square wave that 5 frequencies are 2.5Hz, and the working time is
0.2s, error is less than ± 10%, preceding pulse maximum current intensity when standard termination from minimum 0mA to
Big 4.35mA, points 8 grades are adjustable, and wherein 1 grade be 0mA, and 8 grades: 4.35mA, error is less than ± 10%；
Step 2: after the self-oscillation circuit of ultrasonic module produces sine wave, the ultrasonic exciting of ultrasonic module
Current modulating circuit receives the control signal that single-chip microcomputer main control module sends, and is modulated into frequency modulation(PFM) excitation
Signal, this signal is amplified and exports to treatment head, through treatment head by ultrasonic exciting current amplification circuit
Produce ultrasound wave, and described ultrasound wave is sent to human body site of action through the medium on treatment head.Preposition
The basic waveform of pulse be pulsewidth be 0.25mS, dutycycle is the square wave of 1:1, error be not more than ± 10%,
Several modulating frequencies are that the pulsation half-sinusoid of 100Hz forms a pulsation wave group, the cycle that wave group occurs
Divide from 2.5S to 0.5S 8 grades adjustable, wherein 1 grade is 2.5S, and 8 grades is 0.5S, error be less than ± 10%；
Each wave group is pulsed working time of half-sinusoid from minimum 20mS to maximum 500mS, points 8 grades are adjustable,
Wherein 1 grade is 20mS, 8 grades: for 500mS.
Step 3: produce output continuously by pulse control module or be interrupted the media drive pulse electricity of output
Stream, excitation peak voltage is 100Vp-p, franchise < ± 20%；With step 2 produce ultrasound wave by treating head
After medium synchronism output, produce ultrasound wave and drive electric current synergism, ordering about medium molecule to target
Tissue transmits.The ultrasonic natural frequency that treatment head produces is 1MHz, franchise < ± 30%；Ultrasonic output ripple
The cycle of ripple divide from 2.5S to 0.5S 8 grades adjustable, wherein 1 grade is 2.5S, and 8 grades is 0.5S, and error is little
In ± 10%；The working time of ultrasonic pulsating wave, points 8 grades were adjustable from minimum 0 to maximum 0.5S, and wherein 1
It is 0.5S that shelves are 0,8 grades, franchise < ± 5%.
The foregoing is only preferable combination implementation example of the present utility model, not new in order to limit this practicality
Type, all within spirit of the present utility model and principle, any modification, equivalent substitution and improvement etc. made,
Within should be included in protection domain of the present utility model.
Claims (6)
1. a ultrasonic conductivity meter, including power supply, transformator, mainboard, display operation panel and treatment head, described power supply, transformator, mainboard, display panel are sequentially connected electrically, treatment head electrically connects with mainboard, it is characterized in that, mainboard includes that ultrasonic module, pulse control module, single-chip microcomputer main control module and over-current detection module, treatment head include ultrasonic transducer, electrode and shell, wherein
Described ultrasonic module includes self-oscillation circuit, ultrasonic exciting current modulating circuit, the control signal that single-chip microcomputer main control module sends is by ultrasonic exciting current modulating circuit modulated sinusoid and produces ultrasonic excitation signal, this signal is amplified by ultrasonic exciting current amplification circuit, and is given treatment head by output after self-maintained circuit generation sine wave；
Described pulse control module includes pulse signal generating unit, amplifying unit and modulating unit, and pulse control module, for receiving the control signal that single-chip microcomputer main control module sends, produces multiple pulse wave group and exports to treatment head；
Described single-chip microcomputer main control module, for receiving the parameter signal of display operation panel output, and controls described ultrasonic module and pulse control module according to this parameter signal output control signal；Described over-current detection module receives the control signal that single-chip microcomputer main control module sends, and with reference to the electric current for the treatment of head feedback, the electric current controlling pulse control module output is strong and weak；
Described display operation panel includes parameter set unit and guidance panel, for being sent to single-chip microcomputer main control module by arranging command signal, and shows order parameter and the duty for the treatment of head of setting.
Ultrasonic conductivity meter the most according to claim 1, it is characterised in that described ultrasonic transducer includes inductance, resistance, piezoelectric ceramic piece.
Ultrasonic conductivity meter the most according to claim 1, it is characterised in that it is then in parallel that described self-oscillation circuit includes that audion U6, audion U7 and auxiliary circuit, audion U6 and audion U7 are connected in auxiliary circuit.
Ultrasonic conductivity meter the most according to claim 1, it is characterised in that described ultrasonic exciting current modulating circuit includes audion Q5, audion Q6, audion U5, resistance and diode D1001, audion Q5, audion Q6, audion U5, resistance and diode D1001 electrical connection；The sine wave that ultrasonic exciting current-modulation electricity produces for modulating self-maintained circuit obtains control signal is motivated by ultrasound.
Ultrasonic conductivity meter the most according to claim 1, it is characterised in that described single-chip microcomputer main control module is made up of single-chip microcomputer and peripheral circuit, and peripheral circuit includes crystal oscillator and electric capacity.
Ultrasonic conductivity meter the most according to claim 1, it is characterised in that described over-current detection module includes negative feedback voltage amplifier and pin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620249952.1U CN205698888U (en) | 2016-03-29 | 2016-03-29 | A kind of ultrasonic conductivity meter |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620249952.1U CN205698888U (en) | 2016-03-29 | 2016-03-29 | A kind of ultrasonic conductivity meter |
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| CN205698888U true CN205698888U (en) | 2016-11-23 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105771081A (en) * | 2016-03-29 | 2016-07-20 | 北京中美联医学科学研究院有限公司 | Ultrasonic conductivity meter and ultrasonic delivery method thereof |
| CN107320842A (en) * | 2017-08-14 | 2017-11-07 | 长春市罡恒电子有限责任公司 | Low frequency ultrasound leads medicine instrument |
-
2016
- 2016-03-29 CN CN201620249952.1U patent/CN205698888U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105771081A (en) * | 2016-03-29 | 2016-07-20 | 北京中美联医学科学研究院有限公司 | Ultrasonic conductivity meter and ultrasonic delivery method thereof |
| CN107320842A (en) * | 2017-08-14 | 2017-11-07 | 长春市罡恒电子有限责任公司 | Low frequency ultrasound leads medicine instrument |
| CN107320842B (en) * | 2017-08-14 | 2023-03-24 | 长春市罡恒电子有限责任公司 | Low-frequency ultrasonic medicine guide instrument |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20240126 Address after: Room 07A, Building D, 7th Floor, No.28 Information Road, Haidian District, Beijing, 100085 Patentee after: Beijing Noah Tongzhou Medical Technology Co.,Ltd. Country or region after: China Address before: Room 102, Building No. 1, 80 South College Road, Haidian District, Beijing 100080 Patentee before: BEIJING ZHONGMEILIAN MEDICAL SCIENCE RESEARCH INSTITUTE CO.,LTD. Country or region before: China |