CN203507337U - Ultrasonic tumor treatment apparatus - Google Patents

Ultrasonic tumor treatment apparatus Download PDF

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Publication number
CN203507337U
CN203507337U CN201320480000.7U CN201320480000U CN203507337U CN 203507337 U CN203507337 U CN 203507337U CN 201320480000 U CN201320480000 U CN 201320480000U CN 203507337 U CN203507337 U CN 203507337U
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China
Prior art keywords
tumor
ultrasonic transducer
ultrasonic
ultrasound wave
fluorine carbon
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Expired - Lifetime
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CN201320480000.7U
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Chinese (zh)
Inventor
张晓峰
肖遂宁
黄继宏
王慧海
吴睿
孟庆前
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SHENZHEN ET MEDICAL TECHNOLOGY CO LTD
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SHENZHEN ET MEDICAL TECHNOLOGY Co Ltd
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Abstract

The utility model relates to an ultrasonic tumor treatment apparatus which comprises a fluorocarbon liquid drop, a positioning unit, a gathering unit and a blocking unit, wherein the positioning unit is used for positioning positions of a tumor on a body and injecting the fluorocarbon liquid drop into a blood vessel; the gathering unit comprises a first ultrasonic transducer which generates ultrasonic waves focused on the tumor, so that the fluorocarbon liquid drop in the blood vessel is gathered in the tumor, and the first ultrasonic transducer works under 3 MHz to 7.5 MHz; and the blocking unit comprises a second ultrasonic transducer which generates low-frequency and high-pressure ultrasonic waves focused on the tumor, so that the fluorocarbon liquid drop gathered in the tumor can be gasified, and the second ultrasonic transducer works under 0.8 MHz to 2 MHz. According to the ultrasonic tumor treatment apparatus, the fluorocarbon liquid drop is gathered to the tumor through the blood vessel by means of the ultrasonic waves and then gasified under the action of the ultrasonic waves, the volume of the fluorocarbon liquid drop is expanded, and embolism is formed. The ultrasonic tumor treatment apparatus is simple in structure, free of toxic and side effects and is good in treatment effect.

Description

A kind of ultrasonic tumor device
Technical field
This utility model relates to a kind of therapeutic apparatus for treating tumor, relates in particular to a kind of ultrasonic and therapeutic apparatus for treating tumor fluorine carbon drop that utilizes.
Background technology
Tumor is the principal disease that threatens human life's health, and main treatment means is chemotherapy, radiotherapy and operative treatment at present.But the means of antitumor drug combined chemotherapy, radiotherapy and operative treatment, its effect is indubitable, but all there is certain defect, in killing tumor cell, surrounding normal cell is also inevitably caused to damage with organizing, especially chemotherapy and radiation, also can produce the toxic and side effects such as bone marrow depression.Therefore, find that targeting is good, treatment means that there is no toxic and side effects is the development trend of current oncotherapy.In prior art, adopt ultrasonic technique to carry out oncotherapy, make blood vessel cavitation so that the blood in blood vessel blocks, but this residence time is short by ultrasonication, can not damage for a long time the pressure that keeps blood vessel, therapeutic effect is not good.
Utility model content
The technical problem that this utility model solves is: build a kind of ultrasonic tumor device, overcome prior art and utilize the not good technical problem of ultrasonic cavitation treatment tumor effect.
The technical solution of the utility model is: build a kind of ultrasonic tumor device, comprise positioning unit, accumulation unit, block unit, to described tumor, the position at health positions described positioning unit, described accumulation unit comprises the first ultrasonic transducer, the ultrasound wave of described the first ultrasonic transducer generating 3MHz to 7.5MHz frequency focuses on tumor, fluorine carbon drop in blood is converged in tumor, described obstruction unit comprises the second ultrasonic transducer, the low-frequency high-voltage ultrasound wave of described the second ultrasonic transducer generating 0.8 MHz to 2MHz frequency focuses on tumor, make to converge to the fluorine carbon droplets vaporize of tumor.
Further technical scheme of the present utility model is: described the first ultrasonic transducer and described the second ultrasonic transducer are ultrasound transducer array.
Further technical scheme of the present utility model is: also comprise the time-sequence control mode of controlling ultrasonic transducer sequential in described ultrasound transducer array.
Further technical scheme of the present utility model is: also comprise monitoring means, in described monitoring means monitoring tumor, fluorine carbon drop converges.
Further technical scheme of the present utility model is: described the first ultrasonic transducer generation ultrasound wave, described 8,000,000 ten thousand pulse periods of pulse period to 1200 of ultrasound wave continuous action, described ultrasound wave acoustic pressure is 50KPa.
Further technical scheme of the present utility model is: described the second ultrasonic transducer generation ultrasound wave, and described ultrasound wave continuous action connects 3 times, each 5 recurrent pulses, acoustic pressure is 2MPa.
Further technical scheme of the present utility model is: described positioning unit is for comprising the 3rd ultrasonic transducer.
Further technical scheme of the present utility model is: described the first ultrasonic transducer, described the second ultrasonic transducer, described the 3rd ultrasonic transducer are integrated in one.
Further technical scheme of the present utility model is: described the first ultrasonic transducer and described the 3rd ultrasonic transducer are one group of ultrasonic transducer.
Technique effect of the present utility model is: build a kind of ultrasonic tumor device, comprise fluorine carbon drop, positioning unit, accumulation unit, block unit, to described tumor, the position at health positions described positioning unit, by in fluorine carbon drop injected into blood vessel, described accumulation unit comprises the first ultrasonic transducer, the ultrasound wave that described the first ultrasonic transducer generating focuses on tumor converges in tumor the fluorine carbon drop in blood, described the first ultrasonic transducer is operated in 3MHz to 7.5MHz, described obstruction unit comprises the second ultrasonic transducer, the low-frequency high-voltage ultrasound wave that described the second ultrasonic transducer generating focuses on tumor makes to converge to the fluorine carbon droplets vaporize of tumor, described the second ultrasonic transducer is operated in 0.8 MHz to 2MHz.Ultrasound tumor therapeutic system of the present utility model, is pooled in tumor by blood vessel fluorine carbon drop by ultrasound wave, then under hyperacoustic effect, gasifies, and volumetric expansion forms thromboembolism.Ultrasound tumor therapeutic system of the present utility model, simple in structure, do not there is toxic and side effects, therapeutic effect is good.
Accompanying drawing explanation
Fig. 1 is structural representation of the present utility model.
Fig. 2 is this utility model optimal way structural representation.
Fig. 3 is this utility model therapy system structural representation.
The specific embodiment
Below in conjunction with specific embodiment, technical solutions of the utility model are further illustrated.
As shown in Figure 1, the specific embodiment of the present utility model is: build a kind of ultrasonic tumor device, comprise positioning unit 1, accumulation unit 2, block unit 3, 1 pair of described tumor of described positioning unit positions in the position of health, described accumulation unit 2 comprises the first ultrasonic transducer, described the first ultrasonic transducer generating ultrasound wave, described ultrasound wave with the frequency focusing of 3MHz to 7MHz in tumor, fluorine carbon drop in blood is converged in tumor, described obstruction unit 3 comprises the second ultrasonic transducer, described the second ultrasonic transducer generating low-frequency high-voltage ultrasound wave, described low-frequency high-voltage ultrasound wave arrives tumor with the frequency focusing of 0.8 MHz to 2MHz, make to converge to the fluorine carbon droplets vaporize of tumor.
As shown in Figure 1, specific implementation process of the present utility model is: 1 pair of described tumor of described positioning unit positions in the position of health, concrete localization method comprises: adopt ultrasound wave to tumor locus imaging, by imaging analysis, determine that tumor is in the position of health, comprise the mode imaging that adopts X-ray or MRI.By blood vessel to patient infusion fluorine carbon drop, described accumulation unit 2 comprises the first ultrasonic transducer, described the first ultrasonic transducer produces ultrasound wave to tumor, this ultrasound wave with the frequency focusing of 3MHz to 7.5MHz in tumor, by regulating its effect frequency and cycle and acoustic pressure, the fluorine carbon drop in blood is converged in tumor.In this utility model, described ultrasound wave with the frequency focusing of 3MHz to 7.5MHz in tumor continuous action 2 to 5 seconds, fluorine carbon drop in blood is converged in tumor, in specific embodiment, described ultrasound wave is with the frequency focusing of 5MHz in tumor continuous action 3 seconds, and the fluorine carbon drop in blood can converge in tumor preferably.Described obstruction unit 3 comprises the second ultrasonic transducer, and described the second ultrasonic transducer produces low-frequency high-voltage ultrasound wave to tumor, by regulating its effect frequency and cycle and acoustic pressure, makes to converge to the fluorine carbon droplets vaporize of tumor.In this utility model, described low-frequency high-voltage ultrasound wave arrives tumor continuous action 5 to 15 microseconds with the frequency focusing of 0.8 MHz to 2MHz, makes to converge to the fluorine carbon droplets vaporize of tumor, in gasification, the moment increase of fluorine carbon drop, causes the blood in tumor to block, and cuts off tumor feeding.In specific embodiment, described low-frequency high-voltage ultrasound wave arrives tumor continuous action 10 microseconds with the frequency focusing of 1.5 MHz, and the fluorine carbon drop that converges to tumor is easily vaporized.
As shown in Figure 1, preferred implementation of the present utility model is: described the first ultrasonic transducer and described the second ultrasonic transducer are ultrasound transducer array.In specific embodiment, described ultrasonic transducer is arranged in linear array, also comprises the time-sequence control mode of controlling ultrasonic transducer sequential in described ultrasound transducer array.During use, by time-sequence control mode, control each ultrasonic transducer hyperacoustic time occurs, to form the ultrasonic transducer of ultrasound transducer array, hyperacoustic time synchronized occurs.
As shown in Figure 1, preferred implementation of the present utility model is: also comprise monitoring means 4, the situation that converges of fluorine carbon drop in described monitoring means 4 monitoring tumors, determined for second ultrasonic transducer generating hyperacoustic opportunity according to the situation of converging.Described monitoring means 4 is ultrasonic transducer, by this ultrasonic transducer generating ultrasound wave to tumor imaging, to carry out monitoring analysis.
As shown in Figure 2, preferred implementation of the present utility model is: described positioning unit 1 is for comprising the 3rd ultrasonic transducer.Described the first ultrasonic transducer, described the second ultrasonic transducer, described the 3rd ultrasonic transducer are integrated in one.In specific embodiment, described the first ultrasonic transducer, described the 3rd ultrasonic transducer are same group of ultrasonic transducer, described the second ultrasonic transducer comprises two ultrasonic transducer linear arraies, be arranged in respectively the two ends of described the first ultrasonic transducer, these two ultrasonic transducer linear array acoustic beams are overlapping at 0.8cm to the 5cm place of middle described the second ultrasonic transducer of distance.The ultrasonic transducer linear array at the two ends of described the first ultrasonic transducer and the pinch of centrage are 3 to 12 degree.
As shown in Figure 3, the specific embodiment of the present utility model is: build a kind of ultrasound tumor therapeutic system, comprise fluorine carbon drop 5, positioning unit 1, accumulation unit 2, block unit 3, 1 pair of described tumor of described positioning unit positions in the position of health, by in fluorine carbon drop 5 injected into blood vessel, described accumulation unit 2 comprises the first ultrasonic transducer, described the first ultrasonic transducer generating ultrasound wave, described ultrasound wave with the frequency focusing of 3MHz to 7.5MHz in tumor and the fluorine carbon drop in blood is converged in tumor, described obstruction unit 3 comprises the second ultrasonic transducer, described the second ultrasonic transducer generating low-frequency high-voltage ultrasound wave, described low-frequency high-voltage ultrasound wave with the frequency focusing of 0.8 MHz to 2MHz to tumor and make to converge to the fluorine carbon droplets vaporize of tumor.
As shown in Figure 3, specific implementation process of the present utility model is: 1 pair of described tumor of described positioning unit positions in the position of health, concrete localization method comprises: adopt ultrasound wave to tumor locus imaging, by imaging analysis, determine that tumor is in the position of health, comprise the mode imaging that adopts X-ray or MRI.By blood vessel to patient infusion fluorine carbon drop 5, described accumulation unit 2 comprises the first ultrasonic transducer, described the first ultrasonic transducer produces ultrasound wave to tumor, described ultrasound wave with the frequency focusing of 3MHz to 7.5MHz in tumor continuous action 2 to 5 seconds, by regulating its frequency and duration and acoustic pressure, the fluorine carbon drop in blood is converged in tumor.Described obstruction unit 3 comprises the second ultrasonic transducer, described the second ultrasonic transducer produces low-frequency high-voltage ultrasound wave to tumor, described low-frequency high-voltage ultrasound wave arrives tumor continuous action 5 to 15 microseconds with the frequency focusing of 0.8 MHz to 2MHz, and the fluorine carbon drop 5 that converges to tumor is gasified, in gasification, the moment increase of fluorine carbon drop, causes the blood in tumor to block, and cuts off tumor feeding.
As shown in Figure 3, preferred implementation of the present utility model is: also comprise monitoring means 4, the situation that converges of fluorine carbon drop in described monitoring means 4 monitoring tumors, determined for second ultrasonic transducer generating hyperacoustic opportunity according to the situation of converging.Described monitoring means 4 is ultrasonic transducer, by this ultrasonic transducer generating ultrasound wave to tumor imaging, to carry out monitoring analysis.
Preferred implementation of the present utility model is: described the first ultrasonic transducer generation ultrasound wave, described ultrasound wave with the frequency focusing of 3MHz to 7.5MHz in 8,000,000 ten thousand pulse periods of pulse period to 1200 of tumor continuous action, described ultrasound wave acoustic pressure is 50KPa, by acting on tumor, the fluorine carbon drop 5 in blood is converged in tumor.In specific embodiment, described ultrasound wave with the frequency focusing of 3MHz to 7.5MHz in 1,000 ten thousand pulse periods of tumor continuous action.
Preferred implementation of the present utility model is: described the second ultrasonic transducer generation low-frequency high-voltage ultrasound wave, described low-frequency high-voltage ultrasound wave connects 3 times to tumor continuous action with the frequency focusing of 0.8 MHz to 2MHz, each 5 recurrent pulses, acoustic pressure is-2MPa to 2MPa to make to converge to fluorine carbon drop 5 gasifications of tumor.Described fluorine carbon drop 5 comprises the mixed solution of fluorine carbon micro-nano particle and phospholipid.
Technique effect of the present utility model is: build a kind of ultrasonic tumor device, comprise positioning unit 1, accumulation unit 2, block unit 3, 1 pair of described tumor of described positioning unit positions in the position of health, described accumulation unit 2 comprises the first ultrasonic transducer, described the first ultrasonic transducer generating ultrasound wave, described ultrasound wave with the frequency focusing of 3MHz to 7.5MHz in tumor continuous action 2 to 5 seconds, fluorine carbon drop in blood is converged in tumor, described obstruction unit 3 comprises the second ultrasonic transducer, described the second ultrasonic transducer generating ultrasound wave, described ultrasound wave arrives tumor continuous action 5 to 15 microseconds with the frequency focusing of 0.8 MHz to 2MHz, make to converge to the fluorine carbon droplets vaporize of tumor.Ultrasound tumor therapeutic system of the present utility model, is pooled in tumor by blood vessel fluorine carbon drop by ultrasound wave, then under hyperacoustic effect, gasifies, and volumetric expansion forms thromboembolism.Ultrasound tumor therapeutic system of the present utility model, simple in structure, do not there is toxic and side effects, therapeutic effect is good.
Above content is in conjunction with concrete preferred implementation further detailed description of the utility model, can not assert that concrete enforcement of the present utility model is confined to these explanations.For this utility model person of an ordinary skill in the technical field, without departing from the concept of the premise utility, can also make some simple deduction or replace, all should be considered as belonging to protection domain of the present utility model.

Claims (7)

1. a ultrasonic tumor device, it is characterized in that, comprise positioning unit, accumulation unit, block unit, to described tumor, the position at health positions described positioning unit, described accumulation unit comprises the first ultrasonic transducer, described the first ultrasonic transducer generating ultrasound wave, described ultrasound wave with the frequency focusing of 3MHz to 7.5MHz in tumor, fluorine carbon drop in blood is converged in tumor, described obstruction unit comprises the second ultrasonic transducer, described the second ultrasonic transducer generating low-frequency high-voltage ultrasound wave, described low-frequency high-voltage ultrasound wave arrives tumor with the frequency focusing of 0.8 MHz to 2MHz, make to converge to the fluorine carbon droplets vaporize of tumor.
2. ultrasonic tumor device according to claim 1, is characterized in that, described the first ultrasonic transducer and described the second ultrasonic transducer are ultrasound transducer array.
3. ultrasonic tumor device according to claim 2, is characterized in that, also comprises the time-sequence control mode of controlling ultrasonic transducer sequential in described ultrasound transducer array.
4. ultrasonic tumor device according to claim 1, is characterized in that, also comprises monitoring means, and in described monitoring means monitoring tumor, fluorine carbon drop converges.
5. ultrasonic tumor device according to claim 1, is characterized in that, described positioning unit comprises the 3rd ultrasonic transducer.
6. ultrasonic tumor device according to claim 5, is characterized in that, described the first ultrasonic transducer, described the second ultrasonic transducer, described the 3rd ultrasonic transducer are integrated in one.
7. ultrasonic tumor device according to claim 5, is characterized in that, described the first ultrasonic transducer and described the 3rd ultrasonic transducer are one group of ultrasonic transducer.
CN201320480000.7U 2013-08-07 2013-08-07 Ultrasonic tumor treatment apparatus Expired - Lifetime CN203507337U (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103386169A (en) * 2013-08-07 2013-11-13 深圳市一体医疗科技股份有限公司 Ultrasonic tumor treatment device and treatment system
CN106551722A (en) * 2017-01-03 2017-04-05 中国科学院化学研究所 A kind of RF therapy system
WO2019119429A1 (en) * 2017-12-22 2019-06-27 中国科学院深圳先进技术研究院 Dual-transducer compensation imaging method and ultrasonic imaging system

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103386169A (en) * 2013-08-07 2013-11-13 深圳市一体医疗科技股份有限公司 Ultrasonic tumor treatment device and treatment system
CN106551722A (en) * 2017-01-03 2017-04-05 中国科学院化学研究所 A kind of RF therapy system
WO2019119429A1 (en) * 2017-12-22 2019-06-27 中国科学院深圳先进技术研究院 Dual-transducer compensation imaging method and ultrasonic imaging system

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Owner name: SHENZHEN ENERGY TECHNOLOGY, INC.

Free format text: FORMER NAME: SHENZHEN ET MEDICAL TECHNOLOGY CO., LTD.

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Address after: 518000, Nanshan District Shenzhen science and Technology Park, Guangdong Province, North Hill, two road, clean Sunshine Garden

Patentee after: SHENZHEN ET MEDICAL TECHNOLOGY CO.,LTD.

Address before: 518000, Nanshan District Shenzhen science and Technology Park, Guangdong Province, North Hill, two road, clean Sunshine Garden

Patentee before: Shenzheng Et Medical Technology Co.,Ltd.

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Address after: No.1 Workshop A601, MeiXun digital technology factory, No.19 Jinxiu Middle Road, Laokeng community, Longtian street, Pingshan District, Shenzhen, Guangdong 518000

Patentee after: SHENZHEN ET MEDICAL TECHNOLOGY CO.,LTD.

Address before: 518000 clean Sunshine Park, Langshan Second Road, North District, science and Technology Park, Nanshan District, Shenzhen, Guangdong

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CX01 Expiry of patent term

Granted publication date: 20140402