CN101670058B - Traditional Chinese medicine composition for treating gout - Google Patents
Traditional Chinese medicine composition for treating gout Download PDFInfo
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- CN101670058B CN101670058B CN2009100191898A CN200910019189A CN101670058B CN 101670058 B CN101670058 B CN 101670058B CN 2009100191898 A CN2009100191898 A CN 2009100191898A CN 200910019189 A CN200910019189 A CN 200910019189A CN 101670058 B CN101670058 B CN 101670058B
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Abstract
The invention relates to a traditional Chinese medicine composition for treating gout, which comprises the following raw material medicine components in proportion by weight: 10-40g of caulis lonicerae, 5-20g of gentiana macrophylla, 5-20g of dried rhizome of rehmannia, 15-45g of ramulus mori, 5-12g of prepared radix aconiti, 5-12g of prepared kusnezoff monkshood root, 3-10g of liquorice, 5-25g of rhizoma anemarrhenae, 2-10g of aconite, 5-25g of angelica, 5-25g of pawpaw, 5-25g of root of radix stephaniae tetrandrae, 5-25g of alisma orientale, 10-50g of coix seed, 5-25g of tuckahoe and 5-25g of clematis chinensis. The medicine formulations are fine selected, and through dialectic compatibility, the medicine components are complementary on action, have synergetic functions, can promote blood circulation, regulate purine metabolism, inhibit uric acid formation, enhance human immunity, and achieve the purpose of treating both principal and secondary aspects of diseases. The medicine composition has convenient preparation, wide medicinal resources, low cost, rapid curative effect, high cure rate and no toxic or side effect. Clinical application proves that the total effective rate reaches more than 90 percent, and the cure rate reaches 60 percent.
Description
Technical field
The present invention relates to a kind of pharmaceutical preparation of not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of gout.
Background technology
Gout (Gout) is that the purine of human body gets muddled in synthetic and catabolic process, makes the synthetic increase of uric acid or gets rid of minimizing, accumulates the hyperuricemia that causes in vivo.When the blood uric acid excessive concentration, uric acid promptly is deposited in joint, soft tissue, cartilage and the kidney with the form of sodium salt, causes the foreign body inflammatory reaction of tissue.Show that according to Chinese disease in 2004 and health survey center analysis report China hyperuricemia patient number reaches 1.2 hundred million at present, its patient with gout surpasses 7,500 ten thousand people, and just increases with annual 0.97% annual rate of growth.Gout is actual to be a kind of and the closely-related metabolic disease of life, mainly be because modern's living standard improves, in the process of indulging oneself in eating and drinking, unconsciously taken in too much and the relevant high purine diet of gout morbidity, and cause the generation of gout, promptly gout is a kind of affluenza that eats.
At present, adopt Western medicine to treat patient with gout at the symptom selectivity that different times showed clinically.Used medicine mainly contains three classes: 1, promote the medicine of urate excretion, and as benzbromarone, probenecid, sulphinpyrazone etc.; 2, the medicine that suppresses uricopoiesis is as allopurinol (unique application clinically); 3, easing pain and diminishing inflammation class medicine is as colchicine, nonsteroidal antiinflammatory drug, glucocorticoid indometacin, phenylbutazone class, ibuprofen class, piroxicam, prednisone, dexamethasone etc.But said medicine can only be used for mitigate the disease, takes said medicine for a long time and can produce toxic and side effects to human liver, kidney.
The traditional Chinese medical science thinks that to the gout pathogeny its reason has: innate excess of YANG in the body, internal organs accumulate poison, damp and hot turbid poison, insufficiency of the spleen is this, turbid damp is mark, the exopathogen invasion and attack, at above-mentioned pathogeny, adopt based on eliminating evil, by the method for treatment of, expelling wind and cold turbid, heat-clearing and toxic substances removing, promoting blood circulation to remove obstruction in the collateral except that diarrhea due to damp pathogen, carry out dialectical prescription compatibility according to different etiology and pathogenesis, to reach the purpose for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
In order to overcome available technology adopting western medicine gout, can only mitigate the disease, can not effect a permanent cure, and take the deficiency that Western medicine can produce toxic and side effects to human liver, kidney for a long time, the invention provides that a kind of preparation is easy, the medicine source is wide, curative effect is fast, cost is low, cure rate is high, and the Chinese medicine composition of the treatment gout that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of gout is characterized in that: it is made up of following weight raw material medicine components in proportion: Caulis Lonicerae 10-40, Radix Gentianae Macrophyllae 5-20g, Radix Rehmanniae 5-20g, Ramulus Mori 15-45g, Radix Aconiti Preparata 5-12g, Radix Aconiti Kusnezoffii Preparata 5-12g, Radix Glycyrrhizae 3-10g, Rhizoma Anemarrhenae 5-25g, Radix Aconiti Lateralis Preparata 2-10g, Radix Angelicae Sinensis 5-25g, Fructus Chaenomelis 5-25g, Radix Stephaniae Tetrandrae 5-25g, Rhizoma Alismatis 5-25g, Semen Coicis 10-50g, Poria 5-25g, Radix Clematidis 5-25g.
Precedence technique scheme of the present invention is: a kind of Chinese medicine composition for the treatment of gout is characterized in that: it is made up of following weight raw material medicine components in proportion: Caulis Lonicerae 30g, Radix Gentianae Macrophyllae 15g, Radix Rehmanniae 15g, Ramulus Mori 30g, Radix Aconiti Preparata 8g, Radix Aconiti Kusnezoffii Preparata 8g, Radix Glycyrrhizae 6g, Rhizoma Anemarrhenae 15g, Radix Aconiti Lateralis Preparata 6g, Radix Angelicae Sinensis 15g, Fructus Chaenomelis 15g, Radix Stephaniae Tetrandrae 15g, Rhizoma Alismatis 15g, Semen Coicis 30g, Poria 15g, Radix Clematidis 15g.
In the Chinese medicine composition of the present invention: Caulis Lonicerae, cold in nature, sweet in the mouth attaches to the lung and stomach meridians.Cure mainly heat-clearing and toxic substances removing, the dispelling wind collateral dredging is used for the epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle skin infection, rheumatism pyretic arthralgia, redness and swelling of joints burning pain; Radix Gentianae Macrophyllae, property is flat, and acrid in the mouth, hardship are returned stomach, liver, gallbladder meridian.Cure mainly wind-damp dispelling, clearing away damp-heat, stopping numbness pain is used for rheumatic arthralgia, the contracture of muscle arteries and veins, joint is ached, afternoon fever; The Radix Rehmanniae, sweet in the mouth, hardship, cold in nature, GUIXIN, liver, lung meridian.The effect clearing away heat and cooling blood is used for the warm febrile disease blood of joining the army, high fever coma, xerostomia crimson tongue; Ramulus Mori, property is flat, bitter in the mouth.The effect wind-damp dispelling, sharp joint, the row aqueous vapor cures mainly and controls anemofrigid-damp arthralgia, spasm of the limbs, beriberi edema, human body pruritus due to wind pathogen; Radix Aconiti Preparata, hot in nature, acrid in the mouth, hardship, GUIXIN, liver,kidney,spleen warp.Cure mainly expelling wind and removing dampness, antalgic is used for anemofrigid-damp arthralgia, arthralgia, and trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic; Radix Aconiti Kusnezoffii Preparata, hot in nature, acrid in the mouth, hardship, GUIXIN, liver,kidney,spleen warp.Cure mainly expelling wind and removing dampness, antalgic is used for anemofrigid-damp arthralgia, arthralgia, and trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic; Radix Glycyrrhizae, property is flat, and sweet in the mouth is returned 12 warps.Detoxifcation arranged, eliminate the phlegm, pain relieving, spasmolytic be so that pharmacological action such as anticancer cures mainly invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription; The Rhizoma Anemarrhenae, cold in nature, bitter in the mouth, sweet is returned lung, stomach, kidney channel.The function clearing away heat-fire promotes the production of body fluid and moisturizes, cures mainly to be used for fever caused by exogenous pathogenic factors, and the hyperpyrexia excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, the dryness of the intestine constipation; Radix Aconiti Lateralis Preparata, extremely hot in nature, acrid in the mouth, sweet, GUIXIN, kidney.The effect recuperating depleted YANG and rescuing the patient from collapse, it is supporing yang to mend fire, dispersing cold for relieving pain; Radix Angelicae Sinensis, sweet in the mouth, suffering, warm in nature, return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation is used for blood deficiency and yellow complexion, dizzy cardiopalmus, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores; Fructus Chaenomelis, warm in nature, sour in the mouth is returned liver, spleen channel.Cure mainly the suppressing the hyperactive liver Shujin, the stomach function regulating removing dampness is used for the arthralgia chiefly caused by damp pathogen contracture, the heavy pain of waist knee joint acid, the convulsion of vomiting and diarrhoea, beriberi edema; Radix Stephaniae Tetrandrae, bitter in the mouth, suffering, cold in nature, return bladder, lung, spleen channel, the tool inducing diuresis to remove edema, the effect of wind-expelling pain-stopping cures mainly edema, dysuria, rheumatic arthralgia, beriberi swells and ache, and the scabies skin ulcer is swollen, hypertension; Rhizoma Alismatis, cold in nature, sweet in the mouth is returned kidney, urinary bladder channel, cures mainly diuresis, and clearing away damp-heat is used for dysuria, edema distension, the oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Semen Coicis, cool in nature, sweet in the mouth, light.Function cures mainly the spleen invigorating eliminating dampness by diuresis, and eliminating impediment antidiarrheal is used for edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen; Poria sweet in the mouth, light, property is flat, returns spleen, stomach, the heart, urinary bladder channel, has promoting diuresis to eliminate damp pathogen, invigorating spleen and reinforcing stomach, the effect of mind tranquilizing and the heart calming.Be used for edema, dysuria, phlegm retention, dizzy, palpitation with fear due to the retention of water-damp in the body, insufficiency of the spleen body is tired, and the lack of appetite gastral cavity is vexed, has loose bowels in the loose stool, malaise, palpitation with fear insomnia; Radix Clematidis, warm in nature, acrid in the mouth, salty is gone into urinary bladder channel, cures mainly expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, the hypochondriac lump of loosing.
Above-mentioned Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, take expelling wind and cold, heat-clearing and toxic substances removing, remove that diarrhea due to damp pathogen is turbid, the rule of treatment of promoting blood circulation to remove obstruction in the collateral, selected medicament composing prescription, its drug component is through dialectical compatibility, complement each other using, have synergism, its drug effect is better than the effect of single medicine, can blood circulation promoting, regulate purine metabolism, suppress uric acid and form, strengthen body immunity, reach the purpose for the treatment of both the principal and secondary aspects of a disease.Various crude drug in its Chinese medicine composition are the gentle plant amedica of the property of medicine, and are nontoxic, safe and reliable, and prepare easyly, and the medicine source is wide, and cost is low, and curative effect is fast, the cure rate height.
The present invention follows the prescription principle of medication of the traditional Chinese medical science, and various component drug are taked the usefulness that is decocted in water for oral dose, and through the clinical practice checking, total effective rate reaches more than 90%, and cure rate reaches 60%.
The specific embodiment
The invention will be further described below in conjunction with embodiment.
Embodiment 1: a kind of Chinese medicine composition for the treatment of gout, it is made up of following weight raw material medicine components in proportion: Caulis Lonicerae 30g, Radix Gentianae Macrophyllae 15g, Radix Rehmanniae 15g, Ramulus Mori 30g, Radix Aconiti Preparata 8g, Radix Aconiti Kusnezoffii Preparata 8g, Radix Glycyrrhizae 6g, Rhizoma Anemarrhenae 15g, Radix Aconiti Lateralis Preparata 6g, Radix Angelicae Sinensis 15g, Fructus Chaenomelis 15g, Radix Stephaniae Tetrandrae 15g, Rhizoma Alismatis 15g, Semen Coicis 30g, Poria 15g, Radix Clematidis 15g, get said medicine by weight ratio, decocting extracting juice 300ml, be divided into two parts, every day early, take evening for 2 times.Use through clinical patients, cure rate is more than 60%, and total effective rate reaches more than 90%.Curative effect of the present invention is fast, short treating period, cure rate height, cost are low, without any side effects, and particularly centering, severe gout are remarkable.
Embodiment 2: a kind of Chinese medicine composition for the treatment of gout, it is made up of following weight raw material medicine components in proportion: Caulis Lonicerae 10g, Radix Gentianae Macrophyllae 20g, Radix Rehmanniae 20g, Ramulus Mori 15g, Radix Aconiti Preparata 12g, Radix Aconiti Kusnezoffii Preparata 5g, Radix Glycyrrhizae 10g, Rhizoma Anemarrhenae 25g, Radix Aconiti Lateralis Preparata 2g, Radix Angelicae Sinensis 25g, Fructus Chaenomelis 5g, Radix Stephaniae Tetrandrae 25g, Rhizoma Alismatis 25g, Semen Coicis 50g, Poria 5g, Radix Clematidis 25g, get said medicine by weight ratio, decocting extracting juice 300ml, be divided into two parts, every day early, take evening for 2 times.
Embodiment 3: a kind of Chinese medicine composition for the treatment of gout, it is made up of following weight raw material medicine components in proportion: Caulis Lonicerae 40g, Radix Gentianae Macrophyllae 5g, Radix Rehmanniae 5g, Ramulus Mori 45g, Radix Aconiti Preparata 5g, Radix Aconiti Kusnezoffii Preparata 12g, Radix Glycyrrhizae 3g, Rhizoma Anemarrhenae 5g, Radix Aconiti Lateralis Preparata 10g, Radix Angelicae Sinensis 5g, Fructus Chaenomelis 25g, Radix Stephaniae Tetrandrae 5g, Rhizoma Alismatis 5g, Semen Coicis 10g, Poria 25g, Radix Clematidis 5g, get said medicine by weight ratio, decocting extracting juice 300ml, be divided into two parts, every day early, take evening for 2 times.
Embodiment 4: a kind of Chinese medicine composition for the treatment of gout, it is made up of following weight raw material medicine components in proportion: Caulis Lonicerae 20g, Radix Gentianae Macrophyllae 10g, Radix Rehmanniae 10g, Ramulus Mori 25g, Radix Aconiti Preparata 9g, Radix Aconiti Kusnezoffii Preparata 9g, Radix Glycyrrhizae 8g, Rhizoma Anemarrhenae 20g, Radix Aconiti Lateralis Preparata 5g, Radix Angelicae Sinensis 20g, Fructus Chaenomelis 20g, Radix Stephaniae Tetrandrae 20g, Rhizoma Alismatis 20g, Semen Coicis 30g, Poria 18g, Radix Clematidis 18g, get said medicine by weight ratio, decocting extracting juice 300ml, be divided into two parts, every day early, take evening for 2 times.
Embodiment 5: a kind of Chinese medicine composition for the treatment of gout, it is made up of following weight raw material medicine components in proportion: Caulis Lonicerae 25g, Radix Gentianae Macrophyllae 15g, Radix Rehmanniae 18g, Ramulus Mori 35g, Radix Aconiti Preparata 6g, Radix Aconiti Kusnezoffii Preparata 6g, Radix Glycyrrhizae 9g, Rhizoma Anemarrhenae 12g, Radix Aconiti Lateralis Preparata 3g, Radix Angelicae Sinensis 12g, Fructus Chaenomelis 15g, Radix Stephaniae Tetrandrae 18g, Rhizoma Alismatis 12g, Semen Coicis 25g, Poria 8g, Radix Clematidis 10g, get said medicine by weight ratio, decocting extracting juice 300ml, be divided into two parts, every day early, take evening for 2 times.
Chinese medicine composition in embodiment of the invention decocting method is routinely produced medicament, and concrete grammar is as follows: said medicine is put into container, add cold water and cover powder, soaked about 15～20 minutes, add water again and do not have medicine to decoct for about 5 centimetres.Decocted with high heat at a simmer, will be after boiling with slow fire boiling 30-40 minute; Decoct for the second time, decocted 15-20 minute after water boils, twice decoction extracting juice 300ml.
A kind of Chinese medicine composition for the treatment of nervous headache, clinical efficacy is summed up:
One, physical data: this Chinese medicine composition is applied to clinical observation case 120 examples, wherein male 76 examples, and women 44 examples, its age is at 22-60 between year, course of disease 0.5-5.
Two, clinical symptoms performance: the having an intense pain of single or several joints, night-time attack pain can increase the weight of gradually, makes us being difficult to stand, and also diseases such as redness and swelling of joints, heating and tenderness can occur, daytime pain by subtracting, but local pain is aggravated on the contrary sometimes.
Three, usage and dosage and points for attention: during clinical practice, can take the circumstances into consideration to increase and decrease dose according to patient's body weight and age.This Chinese medicine composition potion on the one, twice extracting juice 300ml of decocting divides early, takes for late twice.Fried sticky, pungent and cold and cool food of period in a medicine diet and marine product.
Four, therapeutic effect: in this clinical observation case, after taking medicine 7-15 days, 108 routine patients' pain, stiff, swelling phenomenon are obviously alleviated, took medicine 1-2 month, the uric acid index obviously descends in 91 blood samples of patients after testing, after taking medicine 3-5 month, it is normal to have the interior uric acid index of 72 routine patient's bodies through inspection, the gout transference cure.5 routine patients to no effect react this medicine during the clinical observation.
Five, typical case:
Tall certain, man, 42 years old.Gout 5 years.The extremity multi-joint is lasting outbreak, redness and swelling of joints, heating and tenderness.Often take colchicine with anti-inflammatory analgesic, take allopurinol and suppress uricopoiesis, unsatisfactory curative effect, the uric acid index is about 530um01/L in the blood.Adopt the decoction of Chinese medicine composition preparation of the present invention, period in a medicine is taked the mode of suitable polydipsia water, to increase the urine amount, promotes urate excretion.It is after taking medicine 7 days, and this patient's swelling, tenderness, heating phenomenon make moderate progress, and takes medicine 1 month, and the uric acid index obviously descends in its blood after testing, and after taking medicine 3 months, through detecting its blood uric acid 380um01/L, the complication phenomenon of goat all disappears.Follow up a case by regular visits to and do not see recurrence in 1 year.
Chen, the man, 57 years old, suffered from gout nearly 10 years.Begin pain, swelling around the right big toe when gout is just sent out, take after the prescription on individual diagnosis " colchicine " pain is eased, disappears.Along with repeatedly morbidity later on, pain alternately appears in its bilateral foot thumb first joint, and gout joint knot is arranged, the color and luster dimness, the left side red and swollen pain of short ankle is born, and night is heavier, pain unbearably, bed can not be walked, blood uric acid 680um0I/L, behind the western medicines such as clothes colchicine, allopurinol, can only relief of symptoms, Chinese medicine has also been eaten much, poor effect, seek medical advice everywhere and seek medicine, suffer all kinds of painful the torment.Adopt the decoction of Chinese medicine composition preparation of the present invention, period in a medicine is taked the mode of suitable polydipsia water, to increase the urine amount, promotes urate excretion.It is after taking medicine 15 days, just think that QI and blood is unobstructed, the swelling in affected part, tenderness, heating phenomenon obviously reduce, took medicine 1 month, the uric acid index obviously descends in its blood after testing, after taking medicine 5 months, return to normal value through detecting its blood uric acid, the syndrome of goat all disappears, and routine blood test, routine urinalysis and hepatic and renal function are all normal, follows up a case by regular visits to and does not see recurrence in 2 years.
Claims (2)
1. Chinese medicine composition for the treatment of gout, it is characterized in that: it is made up of following weight raw material medicine components in proportion: Caulis Lonicerae 10-40g, Radix Gentianae Macrophyllae 5-20g, Radix Rehmanniae 5-20g, Ramulus Mori 15-45g, Radix Aconiti Preparata 5-12g, Radix Aconiti Kusnezoffii Preparata 5-12g, Radix Glycyrrhizae 3-10g, Rhizoma Anemarrhenae 5-25g, Radix Aconiti Lateralis Preparata 2-10g, Radix Angelicae Sinensis 5-25g, Fructus Chaenomelis 5-25g, Radix Stephaniae Tetrandrae 5-25g, Rhizoma Alismatis 5-25g, Semen Coicis 10-50g, Poria 5-25g, Radix Clematidis 5-25g.
2. Chinese medicine composition for the treatment of gout, it is characterized in that: it is made up of following weight raw material medicine components in proportion: Caulis Lonicerae 30g, Radix Gentianae Macrophyllae 15g, Radix Rehmanniae 15g, Ramulus Mori 30g, Radix Aconiti Preparata 8g, Radix Aconiti Kusnezoffii Preparata 8g, Radix Glycyrrhizae 6g, Rhizoma Anemarrhenae 15g, Radix Aconiti Lateralis Preparata 6g, Radix Angelicae Sinensis 15g, Fructus Chaenomelis 15g, Radix Stephaniae Tetrandrae 15g, Rhizoma Alismatis 15g, Semen Coicis 30g, Poria 15g, Radix Clematidis 15g.
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| CN103099999B (en) * | 2013-01-21 | 2014-06-04 | 孙新虎 | Traditional Chinese medicine for treating gout disease |
| CN103622019B (en) * | 2013-12-02 | 2015-08-19 | 广西健丰药业有限公司 | A kind of reducing blood lipid, anti-trioxypurine Chinese medicine composition |
| CN103919871B (en) * | 2014-03-21 | 2016-08-17 | 秦翠秀 | A kind of Chinese medicine composition treating gout |
| CN103989992A (en) * | 2014-05-15 | 2014-08-20 | 韦江南 | Traditional Chinese medicine for treating gout |
| CN106620280A (en) * | 2016-11-21 | 2017-05-10 | 李文本 | Traditional Chinese medicine composition for treating gout |
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| CN1836720A (en) * | 2005-06-17 | 2006-09-27 | 本溪天印药业有限公司 | Chinese medicine composition for treating arthritis or gout and preparing method thereof |
| CN1927330A (en) * | 2006-09-05 | 2007-03-14 | 广州固志医药科技有限公司 | Chinese medicine composition for treating gout and preparing method thereof |
| CN101185730A (en) * | 2006-11-21 | 2008-05-28 | 申海莉 | Pain-relieving mixture for treating gouty arthritis |
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| CN1836720A (en) * | 2005-06-17 | 2006-09-27 | 本溪天印药业有限公司 | Chinese medicine composition for treating arthritis or gout and preparing method thereof |
| CN1927330A (en) * | 2006-09-05 | 2007-03-14 | 广州固志医药科技有限公司 | Chinese medicine composition for treating gout and preparing method thereof |
| CN101185730A (en) * | 2006-11-21 | 2008-05-28 | 申海莉 | Pain-relieving mixture for treating gouty arthritis |
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