CN101668421B - 用于治疗甲状旁腺功能亢进和高钙血症的聚阳离子钙调节肽 - Google Patents

用于治疗甲状旁腺功能亢进和高钙血症的聚阳离子钙调节肽 Download PDF

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CN101668421B
CN101668421B CN200780050006.8A CN200780050006A CN101668421B CN 101668421 B CN101668421 B CN 101668421B CN 200780050006 A CN200780050006 A CN 200780050006A CN 101668421 B CN101668421 B CN 101668421B
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peptide
calcium
terminus
residue
aminoterminal
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CN101668421A (zh
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格雷戈里·贝尔
萨拉·瓦尔特
费利克斯·卡里姆
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Kai Pharmaceuticals Inc
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P19/00—Drugs for skeletal disorders
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    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
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    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A61P5/20—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH
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  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
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  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN200780050006.8A 2006-11-16 2007-11-16 用于治疗甲状旁腺功能亢进和高钙血症的聚阳离子钙调节肽 Active CN101668421B (zh)

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US85959706P 2006-11-16 2006-11-16
US60/859,597 2006-11-16
PCT/US2007/085024 WO2008067199A2 (en) 2006-11-16 2007-11-16 Polycationic calcium modulator peptides for the treatment of hyperparathyroidism and hypercalcemic disorders

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CN101668421B true CN101668421B (zh) 2014-05-21

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CN201410164043.3A Pending CN103961686A (zh) 2006-11-16 2007-11-16 用于治疗甲状旁腺功能亢进和高钙血症的聚阳离子钙调节肽

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US (1) US8987200B2 (enExample)
EP (1) EP2086321B1 (enExample)
JP (2) JP5645408B2 (enExample)
KR (1) KR101552843B1 (enExample)
CN (2) CN101668421B (enExample)
AU (1) AU2007325387B2 (enExample)
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CN103961686A (zh) 2014-08-06
WO2008067199A3 (en) 2008-09-18
WO2008067199A2 (en) 2008-06-05
JP2014114296A (ja) 2014-06-26
AU2007325387A1 (en) 2008-06-05
US20090023652A1 (en) 2009-01-22
US8987200B2 (en) 2015-03-24
CA2669914A1 (en) 2008-06-05
EP2086321B1 (en) 2016-08-31
JP2010510244A (ja) 2010-04-02
CN101668421A (zh) 2010-03-10
EP2086321A2 (en) 2009-08-12
JP5645408B2 (ja) 2014-12-24
CA2669914C (en) 2017-11-07
EP2086321A4 (en) 2012-07-04
KR101552843B1 (ko) 2015-09-14
AU2007325387B2 (en) 2014-04-03
KR20090102754A (ko) 2009-09-30

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