CN101658535A - Preparation method of novel hard plaster - Google Patents
Preparation method of novel hard plaster Download PDFInfo
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- CN101658535A CN101658535A CN200910185128A CN200910185128A CN101658535A CN 101658535 A CN101658535 A CN 101658535A CN 200910185128 A CN200910185128 A CN 200910185128A CN 200910185128 A CN200910185128 A CN 200910185128A CN 101658535 A CN101658535 A CN 101658535A
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Abstract
The invention discloses a preparation method of novel hard plaster; colophony, beeswax and seed fat are combined together and are processed into ground substances by high-temperature oil refining; theraw material of traditional Chinese medicines are mixed in the ground substances by extraction and fine-processing, the anti-oxidant propyl gallate is added and is stirred evenly at the same time, soas to prepare the novel hard plaster. The color of the prepared novel hard plaster is close to the traditional black plaster, the shape and action mechanism of the novel hard plaster is basically thesame with the traditional black plaster; the preparation method can be utilized to prepare the plaster with any formula clinically; after one patch of the plaster can be used repeatedly, the originaldrug effect is kept, and the plaster has no stimulation to skin after long-time usage, is good preparation formulation to internal diseases by external therapy and is suitable for commercial production of factories.
Description
Technical field
The invention belongs to a kind of external preparation, specifically relate to prepare a kind of preparation method of novel hard plaster of any Chinese medicine preparation in the clinical practice.
Technical background
Because traditional plumbiferous cause of black plaster is eliminated successively.Many predecessors are prescriptions of black plaster, actively reincarnate in rubber plaster again, but still do not break away from the stimulation of using for a long time skin, and modal is stripping reaction, can make skin erythema iris occur.In order to solve this difficult problem, the cream card of refreshing card in Guizhou and so on has appearred again.Though these plaster is own non-stimulated to skin, it depends on the adhesive plaster card unguentum is fixed on the position of pasting.Immobilization with adhesive tape produces stimulation equally to skin on skin, can not use continuously for a long time.Disclosed lead-free plaster of ZL01135909.9 and preparation method thereof, though solved the leaded existing drawback of traditional black plaster, it also has the following disadvantages:
1, plaster adds man-hour, and the starch in the concentrated solution, cellulose touch the bottom of a pan and just produce pastel, influences the purity of plaster;
2, during plaster outer plaster, because the package effect of plaster, plaster and water generates hydration reaction, the plaster face forms the bean curd slag specimen and changes, and influences therapeutic effect;
3,, make the belt erythema of position that plaster pastes appearance and pruritus takes place because plaster hardness is big, and the plaster periphery produces physical stimulation to skin;
4, because summer in winter temperature contrast is big, the cream card of producing is subjected to the influence in season big, is unfavorable for commodity production.
Summary of the invention
Technical problem to be solved by this invention, provide a kind of can prepare clinical in the cream card of any prescription, it is in the plaster course of processing, drug effect is difficult for destroyed, plaster purity is good, one obedient plaster can use repeatedly repeatedly still can keep original drug effect, a kind of preparation method of novel hard plaster that life-time service is non-stimulated to skin.
Its technical scheme is: a kind of preparation method of novel hard plaster is a substrate with vegetable oil, Colophonium, Cera Flava, and gallic acid third lipoprotein is an antioxidant, and Chinese medicine is raw material;
Each raw material weight component for preparing novel black plaster: 1 kilogram of vegetable oil, Colophonium 10-12 kilogram, 1 kilogram in Cera Flava, gallic acid third lipoprotein 0.01-0.02 kilogram, raw material of Chinese medicine 0.5-3 kilogram;
Raw material of Chinese medicine wherein is the concentrate medicine, also can be that the medicinal decocting of coarse fodder boils or with the extract after the soak with ethanol, can also concentrate medicine coarse fodder both have simultaneously;
It is characterized in that:
1) when the Chinese medicine raw material is the concentrate medicine merely, concentrate medicated powder is thin, sieve, and Colophonium, vegetable oil, Cera Flava are put pot internal heating and melted, heat again " oil refining ", when temperature rises to 320 when spending, " dripping into pearl ", promptly accuse and refine oil successfully,, in cream, spray water droplet from fire, remove " fire-toxin ", removed " fire-toxin ", treated the cream temperature drop when 70-80 spends, raw material of Chinese medicine and gallic acid third lipoprotein have been mixed in the cream, stir evenly, make the cream card;
2) when the Chinese medicine raw material is the coarse fodder medicine merely, the medicinal water boiling and extraction of coarse fodder or extract with soak with ethanol, extracting solution concentrates, dry, powder is thin, sieve, Colophonium, vegetable oil, Cera Flava are put pot internal heating and are melted, and heat " oil refining " is when temperature rises to 320 when spending again, " drip into pearl ", promptly accuse and refine oil successfully, from fire, in cream, spray water droplet, remove " fire-toxin ", removed " fire-toxin ", treat that the cream temperature drop is when 70-80 spends, raw material of Chinese medicine and gallic acid third lipoprotein are mixed in the cream, stirred evenly, make the cream card;
3) when the Chinese medicine raw material be coarse fodder medicine, concentrate medicine both all sometimes simultaneously, concentrate medicated powder is thin, sieve, the coarse fodder medicinal alcohol soaks and extracts or use water boiling and extraction, extracting solution concentrates, dry, powder is thin, sieve, Colophonium, vegetable oil, Cera Flava are put pot internal heating and are melted, and heat " oil refining " is when temperature rises to 320 when spending again, " drip into pearl ", promptly accuse " oil refining " success,, in cream, spray water droplet from fire, remove " fire-toxin ", removed " fire-toxin ", treated the cream temperature drop when 70-80 spends, raw material of Chinese medicine and gallic acid third lipoprotein have been mixed in the cream, stir evenly, make the cream card;
Novel hard plaster provided by the present invention, comparing with the lead-free plaster of ZL01135909.9 has following remarkable advantage:
1, the Cera Flava in this prescription can reduce the toughness of plaster greatly, eliminates the physical stimulation that Colophonium produces skin;
2, plaster substrate makes substrate produce oxidation, polyreaction by the processing method of high temperature oil refining, strengthens the toughness of plaster, and the hydration reaction of avoiding plaster to be occurred has in use kept plaster to the absorption affinity of skin and the transdermal effect of medicine.Also changed the adaptability of plaster to temperature contrast.Also can the suit use in four seasons spring, summer, autumn and winter of a kind of prescription helps commodity production;
3, plaster is adding man-hour, and fusion antioxidant gallic acid third lipoprotein increases the life-span of plaster, and the effect phase prolongs;
4, the coarse fodder medicine passes through machining at low temperature in advance, makes meticulous powder, mixes into to stir evenly in the substrate, and plaster purity height, the quality of making are good.
The technology that the improvement of cream technique " the shape muscle invigorate blood circulation " that 1996 the 12nd periodicals of the present invention and Chinese patent medicine are stepped on provided, though the substrate element that they constitute is basic identical, but their proportioning is different with processing method, but brought two kinds of different technique effects: the one, in plaster substrate based on Colophonium, Colophonium is thickening agent, and vegetable oil is a softening agent.Because their proportioning difference makes the plaster that they are made that old tender branch be arranged.This and water are cooked congee, cooked with rice is a reason.The ratio of water of cooking is little; Cook congee, it is big that the ratio of water is wanted, and ratio all wants suitable.The plaster substrate prescription that the improvement of paste formulation technology " the strong muscle invigorate blood circulation " provided is: Colophonium 1000 grams, and vegetable oil 200 grams, Cera Flava 150 grams that is to say Colophonium: Oleum sesami: Cera Flava=5: 1: 1.5.The matrix formulations that present technique provided is a Colophonium 10-12 kilogram, 1 kilogram of vegetable oil, and 1 kilogram in Cera Flava that is to say Colophonium: vegetable oil: Cera Flava=10-12: 1: 1.The technology of present technique and the improvement of paste formulation technology " the shape muscle invigorate blood circulation " is compared and is one and is that is to say by ointment to have become plaster by quantitative change to qualitative change, makes present technique more flexible in clinical application, more convenient; Simultaneously, because hard plaster has the package effect, the better efficacy that makes the present technique generation; The 2nd, the improvement of paste formulation technology " the strong muscle invigorate blood circulation ", Chinese medicine that is provided and substrate combination mode are: mix in the substrate important, continue to add heat refining again to " dripping into pearl ".Reach the state of " dripping into pearl ", the cream temperature must be near 320 degree.Chinese medicine that present technique provided and substrate combination mode are: spice machining at low temperature in advance is good, and marquis's cream temperature drop is thrown in spice in the cream when 70-80 spends.Two kinds of compound modes of Chinese medicine and substrate produce two kinds of technique effects.Be a kind of be combination under the low temperature, drug effect loss is little, another kind is the combination of cream relaxing the bowels with purgatives of warm nature, the drug effect loss is big.
Present technique is compared with the cream card that comes out in rubber plaster and nearly period thereof, and its advantage is:
1, novel hard plaster is not leaded, and life-time service is non-stimulated to skin.
2, a kind of plaster can use repeatedly repeatedly continuously, still keeps original drug effect, has brought into play the utilization rate of plaster greatly;
3, novel hard plaster only needs the viscosity of self just can adsorb skin, does not need by immobilization with adhesive tape, avoids the stimulation of adhesive plaster card to skin.
4, novel hard plaster is a kind of hard plaster, has the package therapeutical effect, and cutin is loosened, and strengthens the Transdermal absorption of medicine, improves therapeutic effect;
When 5, using, the fragranced that gives out is comparatively dense.
The specific embodiment
Embodiment 1.Take by weighing 1 kilogram in Oleum Sesami, 10 kilograms of Colophonium, 1 kilogram in Cera Flava, 0.01 kilogram of gallic acid third lipoprotein, 0.5 kilogram of Chinese medicine coarse fodder medicament extract;
Production method is as follows:
1, the extraction of Chinese medicine coarse fodder medicine, the extracting method of coarse fodder medicine are water boiling and extraction or alcohol-pickled extraction, and extracting solution is thin through concentrated, drying, powder;
2, Colophonium is smashed;
3, earlier Colophonium, Cera Flava, Oleum Sesami are put into pot, heating and melting, continue to heat to 320 the degree, when reaching " dripping into pearl " from fire, in pot, spray water droplet and remove " fire-toxin ", after releasing fire-toxin finishes, treat the cream temperature drop when 70-80 spends, the extract of coarse fodder medicine is mixed in the cream, throw in gallic acid third lipoprotein again, stir evenly altogether, be attached on the plaster cloth, promptly get novel hard plaster by different specification stand.
Embodiment 2.Take by weighing 1 kilogram of Oleum Arachidis hypogaeae semen, 11 kilograms of Colophonium, 1 kilogram in Cera Flava, 0.015 kilogram of gallic acid third lipoprotein, 2 kilograms of coarse fodder medicament extract, concentrate medicines;
Production method is as follows:
1, the coarse fodder medicinal alcohol soak to extract, extracting solution through concentrating, dry and concentrate medicine respectively porphyrize, sieve;
2, Colophonium is smashed;
3, Colophonium, Cera Flava, Oleum Arachidis hypogaeae semen are put into pot, heating and melting, continue to heat to 320 the degree, when reaching " dripping into pearl " from fire, in pot, spray water droplet and remove " fire-toxin ", after releasing fire-toxin finishes, when treating the cream temperature drop to the 70-80 degree left and right sides, in spice mix in the cream, throw in gallic acid third lipoprotein again, stir evenly altogether, be attached on the plaster cloth, promptly get novel hard plaster by different specification stand.
Embodiment 3.Take by weighing 1 kilogram of Oleum Verniciae fordii, 12 kilograms of Colophonium, 1 kilogram in Cera Flava, 0.02 kilogram of gallic acid third lipoprotein, 3 kilograms of concentrate medicines;
Production method is as follows:
1, concentrate medicine porphyrize sieves;
2, Colophonium is smashed;
3, earlier Colophonium, Cera Flava, Oleum Verniciae fordii are put into pot, heating and melting continues to heat to 320 degree, when reaching " dripping into pearl " from fire, in pot, spray water droplet and remove " fire-toxin ", after releasing fire-toxin finishes, treat that the cream temperature drop is when 70-80 spends, the concentrate medicine is mixed in the cream, thrown in gallic acid third lipoprotein again, stir evenly altogether, be attached on the plaster cloth by different specification stand, promptly get novel hard plaster.
The using method of novel hard plaster is: select the cream card of suitable model, and soft with the fire baking, be attached on affected part or the corresponding acupoints.
Claims (1)
1, a kind of preparation method of novel hard plaster is a substrate with vegetable oil, Colophonium, Cera Flava, and gallic acid third lipoprotein is an antioxidant, and Chinese medicine is raw material;
Each raw material weight component of preparation novel hard plaster: 1 kilogram of vegetable oil, Colophonium 10-12 kilogram, 1 kilogram in Cera Flava, gallic acid third lipoprotein 0.01-0.02 kilogram, raw material of Chinese medicine 0.5-3.5 kilogram;
Raw material of Chinese medicine wherein is the concentrate medicine, also can be that the medicinal decocting of coarse fodder boils or with the extract after the soak with ethanol, can also concentrate medicine coarse fodder both have simultaneously;
It is characterized in that:
1) when the Chinese medicine raw material is the concentrate medicine merely, concentrate medicated powder is thin, sieve, and Colophonium, vegetable oil, Cera Flava are put pot internal heating and melted, heat again " oil refining ", when temperature rises to 320 when spending, " dripping into pearl ", promptly accuse and refine oil successfully,, in cream, spray water droplet from fire, remove " fire-toxin ", removed " fire-toxin ", treated the cream temperature drop when 70-80 spends, raw material of Chinese medicine and gallic acid third lipoprotein have been mixed in the cream, stir evenly, make the cream card;
2) when the Chinese medicine raw material is the coarse fodder medicine merely, the medicinal water boiling and extraction of coarse fodder or extract with soak with ethanol, extracting solution concentrates, dry, powder is thin, sieve, Colophonium, vegetable oil, Cera Flava are put pot internal heating and are melted, and heat " oil refining " is when temperature rises to 320 when spending again, " drip into pearl ", promptly accuse and refine oil successfully, from fire, in cream, spray water droplet, remove " fire-toxin ", removed " fire-toxin ", treat that the cream temperature drop is when 70-80 spends, raw material of Chinese medicine and gallic acid third lipoprotein are mixed in the cream, stirred evenly, make the cream card;
3) when the Chinese medicine raw material be coarse fodder medicine, concentrate medicine both all sometimes simultaneously, concentrate medicated powder is thin, sieve, the coarse fodder medicinal alcohol soaks and extracts or use water boiling and extraction, extracting solution concentrates, dry, powder is thin, sieve, Colophonium, vegetable oil, Cera Flava are put pot internal heating and are melted, and heat " oil refining " is when temperature rises to 320 when spending again, " drip into pearl ", promptly accuse " oil refining " success,, in cream, spray water droplet from fire, remove " fire-toxin ", removed " fire-toxin ", treated the cream temperature drop when 70-80 spends, raw material of Chinese medicine and gallic acid third lipoprotein have been mixed in the cream, stir evenly, make the cream card.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910185128A CN101658535A (en) | 2009-09-29 | 2009-09-29 | Preparation method of novel hard plaster |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910185128A CN101658535A (en) | 2009-09-29 | 2009-09-29 | Preparation method of novel hard plaster |
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| CN101658535A true CN101658535A (en) | 2010-03-03 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN200910185128A Pending CN101658535A (en) | 2009-09-29 | 2009-09-29 | Preparation method of novel hard plaster |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105343035A (en) * | 2015-11-30 | 2016-02-24 | 江苏七O七天然制药有限公司 | Preparation process of plaster |
| CN105343034A (en) * | 2015-10-31 | 2016-02-24 | 韩俊峰 | Black plaster and novel preparation method thereof |
-
2009
- 2009-09-29 CN CN200910185128A patent/CN101658535A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105343034A (en) * | 2015-10-31 | 2016-02-24 | 韩俊峰 | Black plaster and novel preparation method thereof |
| CN105343035A (en) * | 2015-11-30 | 2016-02-24 | 江苏七O七天然制药有限公司 | Preparation process of plaster |
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Application publication date: 20100303 |