CN100441167C - Lead free ointment and preparation process - Google Patents
Lead free ointment and preparation process Download PDFInfo
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- CN100441167C CN100441167C CNB011359099A CN01135909A CN100441167C CN 100441167 C CN100441167 C CN 100441167C CN B011359099 A CNB011359099 A CN B011359099A CN 01135909 A CN01135909 A CN 01135909A CN 100441167 C CN100441167 C CN 100441167C
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- plaster
- chinese medicine
- lead
- concentrate
- coarse fodder
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Abstract
The present invention discloses a plaster without lead and a preparation method for the plaster. The plaster uses vegetable oil and rosin as excipient and traditional Chinese medicine as raw materials, and externally pasted medicine is formed by ethanol as media. The present invention has simple production. When produced, the present invention is not toxic or harmful to human bodies and has no pollution to environment. The bioactivity of the traditional Chinese medicine can not be damaged easily. Moreover, the content of effective medicine can be greatly improved. When used, the plaster without lead can be attached to a sticking position only by the heat force of human bodies, and the plaster can not move when meeting heat. The present invention has no stimulation to skins for long time use. The present invention can prepare any kind of formulation for clinical application. The plaster of the present invention performs the functions of taking advantages of traditional plaster formed by lead and avoiding the defects of the traditional plaster formed by lead.
Description
Technical field:
The invention belongs to a kind of external preparation, saying so particularly relates to the preparation method of the lead-free plaster for preparing any Chinese medicine preparation of clinical practice.
Technical background:
Outer sick external treatment, interior sick treatment by oral administration of medicines, this treatment means method is simple, economy, consumption are little, good effect, no pain, have no side effect, and extremely social parent looks at.To this, corresponding medicine for external use constantly comes out.Traditional black plaster is let slip brilliance greatly in poor and backward old China, but has following shortcoming with the plumbous black plaster of making:
One, complex procedures, technology are difficult to grasp.
Two, add the lead thing gas that produce man-hour, environment is had pollution, toxic to human body.
Three, processing black plaster oil temperature need reach more than 280 ℃, and the biological activity of Chinese medicine is vulnerable to destroy.
Four, a kind of prescription is many as the flavor number, and the effective content of plaster will be subjected to very big restriction, and drug effect is difficult to improve.
Need when five, using plaster its bakingization just can be attached to the affected part, scald pain scalded skin method easily.
Six, it is mobile easily that plaster is met the heat thawing, pollutes clothing.
Seven, the plumbous agent in the plaster is big to skin irritation, the long slightly contact dermatitis that easily produces of subsides time, and the patient feels that the part very itches unbearably, often therapy discontinued.
For overcoming the shortcoming of black plaster, there are many hard plasters to come out on the market again, as " HUOXUE ZHITONG GAO ", " ZHUIFENG GAO ", " SHEXIANG ZHUANGGU GAO " etc.,, skin is still had stimulation because of preparation be unable to do without lead, the patient can not use for a long time.
Summary of the invention:
Technical problem to be solved by this invention provide a kind of have make simple, add the environmentally safe in man-hour, to the effective content of human body nonhazardous, medicine may regulated at will, when using to the preparation method of the non-stimulated external lead-free plaster of skin.
Its technical scheme is: a kind of preparation method of lead-free plaster, the lead-free plaster of preparation are to be excipient with vegetable oil and Colophonium, and Chinese medicine is raw material, and ethanol is medium;
The weight for preparing each component of above-mentioned lead-free plaster is: 1 kilogram of vegetable oil, Colophonium 6-12 kilogram, raw material of Chinese medicine 1-12 kilogram and ethanol 0-100 kilogram;
Wherein raw material of Chinese medicine it can be coarse fodder, also can be concentrate, can also be coarse fodder, concentrate both have simultaneously;
It is characterized in that:
1) when the Chinese medicine raw material only be concentrate, when not containing coarse fodder, earlier concentrate is ground into superfine powder, again Colophonium is smashed the back and put into the thawing of iron pan internal heating with vegetable oil, temperature is mixed the meticulous material of Chinese medicine and is stirred evenly in the time of 60-70 ℃, treats that plaster is when growing paste, according to different specifications the plaster stand is attached on the plaster lining, promptly gets lead-free plaster;
2) when the Chinese medicine raw material be coarse fodder, concentrate both all sometimes simultaneously, earlier the Chinese medicine coarse fodder is concentrated with ethanol extraction and with this extracting solution, again concentrate is ground into superfine powder, then Colophonium is smashed with vegetable oil and put into the thawing of iron pan internal heating, when temperature rises to 100 ℃, in pot, spray the Chinese medicine coarse fodder ethanol extraction concentrated solution of above-mentioned acquisition, wait to have sprayed, no ethanol volatilization in the pot can be from fire, when treating that temperature is reduced to 60-70 ℃, mixing concentrate stirs evenly, treat that plaster is the taste paste, spread out on the plaster lining according to different specifications again, promptly get lead-free plaster; Plaster;
2) when the Chinese medicine raw material be coarse fodder, concentrate both all sometimes simultaneously, earlier the Chinese medicine coarse fodder is concentrated with ethanol extraction and with this extracting solution, again concentrate is ground into superfine powder, then Colophonium is smashed with vegetable oil and put into the thawing of iron pan internal heating, when temperature rises to 100 ℃, in pot, spray the Chinese medicine coarse fodder ethanol extraction concentrated solution of above-mentioned acquisition, wait to have sprayed, no ethanol volatilization in the pot can be from fire, when treating that temperature is reduced to 60-70 ℃, mixing concentrate stirs evenly, treat that plaster is the taste paste, spread out on the plaster lining according to different specifications again, promptly get lead-free plaster;
3) when the Chinese medicine raw material only be coarse fodder, when not containing the situation of concentrate, earlier the Chinese medicine coarse fodder is concentrated with ethanol extraction and with this extracting solution, again Colophonium is smashed with vegetable oil and put into the thawing of iron pan internal heating, when temperature rises to 100 ℃, in pot, spray the Chinese medicine coarse fodder ethanol extraction concentrated solution of above-mentioned acquisition, wait to have sprayed, no ethanol volatilization in the pot, can be from fire, when treating that temperature is reduced to 60-70 ℃, plaster is the taste paste, spread out on the plaster lining according to different specifications again, promptly get lead-free plaster.
The raw material of Chinese medicine of above-mentioned preparation lead-free plaster is clinical applied any prescription.With vegetable oil and Colophonium is the made plaster of excipient, and its form approaches the plaster made with plumbous.
Preparation method of the present invention is compared with traditional plaster production technology, has following remarkable advantage:
One, the present invention is simple for process, and is with short production cycle.Environmentally safe during making is to the human body nonhazardous.
Two, lead-free plaster of the present invention is in the course of processing, and required temperature generally is no more than 100 ℃, so be machining at low temperature, the biological activity of Chinese medicine is difficult for being affected and destroying; Simultaneously, effective medicinal component of Chinese medicine coarse fodder behind ethanol extraction, just can be got involved in the plaster, and concentrate all is to become liposoluble substance behind the preprocess, can directly be incorporated in the plaster.Therefore, can regulate the content of dispersion of lead-free plaster arbitrarily, and these effective medicinal components lipid material generation chemical reaction of generally getting along well.Lipid material has affinity interaction to skin, and medicine carrying is entered a profession in the skin effectively; Plaster has sealing process to the part in addition, and local temperature is raise, vasodilation, and pore opens, and moisture content is not evaporated, and the horny layer water content increases and loosens, and the penetration of liposoluble substance is strengthened, thereby can strengthen the effect of treatment disease.
Three, solution of the present invention is all to be lipid material according to vegetable oil and Colophonium, and Colophonium is solid-state shape at normal temperatures, meets heat and melts, and vegetable oil and Colophonium are merged according to a certain percentage, can reach the suitable plaster of soft or hard.When using the plaster that method of the present invention prepares, as long as plaster and contact skin, under the effect of human body temperature, the plaster of contact site melts immediately, and can tightly be adsorbed on the position of pasting, and difficult mobile, and is pollution-free to clothes; Life-time service is non-stimulated to skin, can use no any discomfort continuously.
Four, utilize preparation method of the present invention, can produce the plaster of any Chinese medicine preparation in the clinical practice arbitrarily.
The specific embodiment:
Embodiment 1.
Take by weighing raw material by following weight:
1 kilogram in Oleum Sesami, 8 kilograms of Colophonium, 1.5 kilograms of raw material of Chinese medicine (concentrate).
Production method is as follows:
1. raw material of Chinese medicine is ground into impalpable powder;
2. Colophonium is smashed;
3. Colophonium is gone into pot internal heating and melt, reenter Oleum Sesami, temperature is mixed the meticulous material of Chinese medicine and is stirred evenly in the time of 60C-70 ℃, treats that plaster is when growing paste, is attached to the plaster stand on the plaster lining according to different specifications.
Embodiment 2.
Take by weighing raw material by following weight:
15 kilograms of 1 kilogram of Oleum Ricini, 6 kilograms of Colophonium, raw material of Chinese medicine 3 kilograms (0.5 kilogram of concentrate, 2.5 kilograms of coarse fodders), ethanol.
Production method is as follows:
The Chinese medicine coarse fodder with ethanol extraction after, discard residue, ethanol extract is concentrated;
2. the Chinese medicine concentrate is ground into impalpable powder;
3. Colophonium is smashed;
4. Colophonium is gone into the thawing of iron pan internal heating, reenters Oleum Ricini, and stirs with club, when temperature is raised to 100 ℃, the ethanol extraction concentrated solution is sprayed in pot, waits to have sprayed, and no ethanol volatilization in the pot can be from fire.When treating that temperature is reduced to 60C-70 ℃, mix concentrate and stir evenly, treat that plaster is the taste paste, spread out on the plaster lining according to different specifications again.
Embodiment 3.
Take by weighing raw material by following weight:
0.5 kilogram of Oleum Verniciae fordii, 0.5 kilogram of Oleum Arachidis hypogaeae semen, 12 kilograms of Colophonium, 12 kilograms of raw material of Chinese medicine (coarse fodder), 100 kilograms of ethanol.
Production method is as follows:
1. the Chinese medicine coarse fodder discards residue after with ethanol extraction, and ethanol extract is concentrated;
2. Colophonium is smashed;
3. Colophonium is gone into a pot heating and melting, reenter Oleum Verniciae fordii, Oleum Arachidis hypogaeae semen, when temperature rises to 100 ℃, in pot, spray the ethanol extraction concentrated solution, sprayed and treated that no ethanol volatilizees in the pot, can be from fire, treat that temperature reduces to about 60 ℃, plaster is when growing paste, according to different specifications the plaster stand is attached on the plaster lining again.
The using method of lead-free plaster: select the cream card of suitable model, directly be attached to affected part or be attached on the corresponding acupoints, when sticking, with hands plaster being sealed two minutes plaster can adsorb.One day or the next day change once.
Claims (1)
1, a kind of preparation method of lead-free plaster, the lead-free plaster of preparation are to be excipient with vegetable oil and Colophonium, and Chinese medicine is raw material, and ethanol is medium;
The weight for preparing each component of above-mentioned lead-free plaster is: 1 kilogram of vegetable oil, Colophonium 6-12 kilogram, raw material of Chinese medicine 1-12 kilogram and ethanol 0-100 kilogram;
Wherein raw material of Chinese medicine it can be coarse fodder, also can be concentrate, can also be coarse fodder, concentrate both have simultaneously;
It is characterized in that:
1) when the Chinese medicine raw material only be concentrate, when not containing coarse fodder, earlier concentrate is ground into superfine powder, again Colophonium is smashed the back and put into the thawing of iron pan internal heating with vegetable oil, temperature is mixed the meticulous material of Chinese medicine and is stirred evenly in the time of 60-70 ℃, treats that plaster is when growing paste, according to different specifications the plaster stand is attached on the plaster lining, promptly gets lead-free plaster;
2) when the Chinese medicine raw material be coarse fodder, concentrate both all sometimes simultaneously, earlier the Chinese medicine coarse fodder is concentrated with ethanol extraction and with this extracting solution, again concentrate is ground into superfine powder, then Colophonium is smashed with vegetable oil and put into the thawing of iron pan internal heating, when temperature rises to 100 ℃, in pot, spray the Chinese medicine coarse fodder ethanol extraction concentrated solution of above-mentioned acquisition, wait to have sprayed, no ethanol volatilization in the pot can be from fire, when treating that temperature is reduced to 60-70 ℃, mixing concentrate stirs evenly, treat that plaster is the taste paste, spread out on the plaster lining according to different specifications again, promptly get lead-free plaster;
3) when the Chinese medicine raw material only be coarse fodder, when not containing the situation of concentrate, earlier the Chinese medicine coarse fodder is concentrated with ethanol extraction and with this extracting solution, again Colophonium is smashed with vegetable oil and put into the thawing of iron pan internal heating, when temperature rises to 100 ℃, in pot, spray the Chinese medicine coarse fodder ethanol extraction concentrated solution of above-mentioned acquisition, wait to have sprayed, no ethanol volatilization in the pot, can be from fire, when treating that temperature is reduced to 60-70 ℃, plaster is the taste paste, spread out on the plaster lining according to different specifications again, promptly get lead-free plaster.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011359099A CN100441167C (en) | 2001-10-17 | 2001-10-17 | Lead free ointment and preparation process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011359099A CN100441167C (en) | 2001-10-17 | 2001-10-17 | Lead free ointment and preparation process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1358496A CN1358496A (en) | 2002-07-17 |
| CN100441167C true CN100441167C (en) | 2008-12-10 |
Family
ID=4673345
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB011359099A Expired - Fee Related CN100441167C (en) | 2001-10-17 | 2001-10-17 | Lead free ointment and preparation process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100441167C (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105769829A (en) * | 2016-05-23 | 2016-07-20 | 宋文宝 | Rosin type lead-free plaster and preparation method thereof |
| CN108653531A (en) * | 2018-05-30 | 2018-10-16 | 湖南众医药咨询有限公司 | A kind of black plaster and preparation method thereof |
| CN109700909A (en) * | 2019-03-19 | 2019-05-03 | 孟召阳 | A kind of preparation method of quick-acting plaster |
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2001
- 2001-10-17 CN CNB011359099A patent/CN100441167C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1358496A (en) | 2002-07-17 |
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Addressee: Xue Hongyang Document name: Notice of first review |
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