CN1358496A - Lead free ointment and preparation process - Google Patents
Lead free ointment and preparation process Download PDFInfo
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- CN1358496A CN1358496A CN 01135909 CN01135909A CN1358496A CN 1358496 A CN1358496 A CN 1358496A CN 01135909 CN01135909 CN 01135909 CN 01135909 A CN01135909 A CN 01135909A CN 1358496 A CN1358496 A CN 1358496A
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- plaster
- chinese medicine
- colophonium
- free
- lead
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Abstract
The present invention discloses a leadless adhesive plaster and its preparation method. It is characterized by that vegetable oil and rosin are used as excipient, Chinese medicine is used as raw material and medium ethyl alcohol is used to prepare the invented medicine for external application. Its production process is simple, and can greatly raise effective medicinal component content, and when the leadless adhesive plaster is used, it can be adsorbed on any position of human body by means of heat quantity of human body, and can not be moved. Said invented leadless adhesive plaster can be produced according to any prescription for clinical application.
Description
Technical field:
The invention belongs to a kind of external preparation, specifically relate to prepare the lead-free plaster of any Chinese medicine preparation of clinical practice, the invention still further relates to the preparation method of lead-free plaster.
Technical background:
Outer sick external treatment, inner disease outer treat, this treatment means method is simple, economical, and consumption is little, good effect, no pain has no side effect, and extremely social parent looks at.To this, corresponding medicine for external use constantly comes out.Traditional black plaster is let slip extraordinary splendor greatly in poor and backward old China, but has following shortcoming with the plumbous black plaster of making.
One, complex procedures.Technology is difficult to grasp.
Two, add the lead thing gas that produce man-hour, environment is had pollution, toxic to human body.
Three, processing black plaster oil temperature need reach more than 280 ℃, and the biological activity of Chinese medicine is vulnerable to destroy.
Four, a kind of prescription is many as the flavor number, and the effective content of plaster will be subjected to very big restriction, and drug effect is difficult to improve.
Need when five, using plaster its bakingization just can be attached to the affected part, scald the pain scalded skin easily.
Six, it is mobile easily that plaster is met the heat thawing, pollutes clothing.
Seven, the plumbous agent in the plaster is big to skin irritation, the long slightly contact dermatitis that easily produces of subsides time, and the patient feels that the part very itches unbearably, often therapy discontinued.
For overcoming the shortcoming of black plaster, have many hard plasters to come out on the market again, as " HUOXUE ZHITONG GAO ", " ZHUIFENG GAO ", " SHEXIANG ZHUANGGU GAO " and etc., because of preparation be unable to do without plumbously, skin is still had stimulation, the patient can not use for a long time.
Goal of the invention:
Technical problem to be solved by this invention provide a kind of have make simply, add the environmentally safe in man-hour, to the human body nonhazardous, the effective content of medicine may regulated at will, the external lead-free plaster non-stimulated to skin during use.
Another object of the present invention provides the preparation method of lead-free plaster.
Solution of the present invention is all to be lipid material according to vegetable oil and Colophonium, and Colophonium is solid-state shape at normal temperatures, meets heat and melts.Vegetable oil and Colophonium are merged according to a certain percentage, can reach the suitable plaster of soft or hard.When plaster and contact skin, under the effect of human body temperature, the plaster face of contact site promptly melts, and can tightly be adsorbed on the position of pasting.
Effective medicinal component of Chinese medicine coarse fodder behind ethanol extraction, can be got involved in the plaster, and concentrate all is to become liposoluble substance behind the preprocess, can directly be incorporated in the plaster.These effective medicinal components lipid material generation chemical reaction of generally getting along well.Lipid material has affinity interaction to skin, and medicine carrying is entered a profession in the skin effectively.Plaster has sealing process to the part in addition, can make local temperature raise vasodilation, pore opens, and moisture is not evaporated, and the horny layer water content increases and loosens, the penetration of liposoluble substance is strengthened, and based on this mechanism of action, this programme is made a kind of lead-free plaster.
Technical scheme:
For reaching the object of the invention, the concrete feature of lead-free plaster is to be excipient with vegetable oil, Colophonium, is raw material with Chinese medicine, is that medium is made with ethanol.The weight of making medicine of the present invention is
1 kilogram of Colophonium 1-12 of vegetable oil kilogram raw material of Chinese medicine 1-12 kilogram ethanol 0-100 kilogram
The raw material of Chinese medicine of preparation lead-free plaster is clinical applied any prescription.It can be coarse fodder for a raw material of Chinese medicine, also can be concentrate, and can also be has coarse fodder, both whiles of concentrate.Described coarse fodder needs to discard residue with the effective medicinal component of ethanol extraction; Described concentrate can directly mix in the plaster.With vegetable oil and Colophonium is the made plaster of excipient, and its form approaches the plaster made with plumbous.
Above-mentioned prescription is made medicine production method of the present invention is:
1, gets the Chinese medicine coarse fodder earlier with the medicinal active ingredient of ethanol extraction, discard residue, then ethanol extract is concentrated;
2, get concentrate and be ground into impalpable powder;
3, getting Colophonium smashes;
4, Colophonium, vegetable oil are put into the fusing of iron pan internal heating, when temperature rises to 100 ℃, in pot, sprayed the ethanol extraction concentrated solution, and in pot, ceaselessly stir with club, all spread up to ethanol extract, no ethanol volatilization can be from fire, when treating that temperature is reduced to 60 ℃-70 ℃ in the pot.Throw concentrate again, a kind of lead-free plaster is promptly made.Can spread out into the plaster subsides that size specification does not wait according to clinical needs.
Technique effect:
An important feature of the present invention is: lead-free plaster is in the course of processing, and required temperature generally is no more than 100 ℃, so that biological activity is difficult for is destroyed.
Another important feature of the present invention, the active ingredient of utilization ethanol extraction Chinese medicine can be regulated the content of dispersion of lead-free plaster arbitrarily.
The present invention compares with the plumbous plaster made from tradition, has following remarkable advantage:
One, the present invention is simple for process, and is with short production cycle.Environmentally safe during making is to the human body nonhazardous.
What two, processing technology of the present invention was taked is machining at low temperature, and the biological activity of Chinese medicine is difficult for being affected, and utilizes ethanol that the active ingredient of medicine is got involved in the plaster, can regulate the content of dispersion of lead-free plaster, strengthens the effect of treatment disease.
Only need utilize human body heating power when three, using, promptly can be adsorbed on the position of pasting, and be difficult for moving, pollution-free to clothes,
Four, life-time service is non-stimulated to skin, can use no any discomfort continuously.
Five, can utilize its preparation method, produce the plaster of any Chinese medicine preparation in the clinical practice arbitrarily.
The appearance of lead-free plaster has been played the effect of maximizing favourable factors and minimizing unfavourable ones to tradition with the plumbous plaster of making.
Embodiment 1
Take by weighing raw material by following weight:
1.5 kilograms of Oleum Sesami 8 kilograms of raw material of Chinese medicine of 1 kilogram of Colophonium (concentrate)
Production method is as follows:
1, raw material of Chinese medicine is ground into impalpable powder;
2, Colophonium is smashed;
3, Colophonium is gone into a pot internal heating fusing, reenter Oleum Sesami, temperature is mixed the meticulous material of Chinese medicine and is stirred evenly in the time of 60 ℃ 70 ℃, treats that plaster is when growing paste, is attached to the plaster stand on the plaster lining according to different specifications.
Embodiment 2
Take by weighing raw material by following weight:
15 kilograms of 3 kilograms of (2.5 kilograms of 0.5 kilogram of coarse fodders of concentrate) ethanol of 6 kilograms of raw material of Chinese medicine of 1 kilogram of Colophonium of Oleum Ricini
Production method is as follows:
1, the Chinese medicine coarse fodder with ethanol extraction after, discard residue, ethanol extract is concentrated;
2, the Chinese medicine concentrate is ground into impalpable powder;
3, Colophonium is smashed;
4, Colophonium is gone into the fusing of iron pan internal heating, reenters Oleum Ricini, and stirs with club, when temperature is raised to 100 ℃, the ethanol extraction concentrated solution is sprayed in pot, waits to have sprayed, and no ethanol volatilization in the pot can be from fire.When treating that temperature is reduced to 60 ℃-70 ℃, mix concentrate and stir evenly, treat that plaster is the taste paste, spread out on the plaster lining according to different specifications again.
Embodiment 3
Take by weighing raw material by following weight
100 kilograms of 12 kilograms of ethanol of Oleum Verniciae fordii 0.5 kilogram of Oleum Arachidis hypogaeae semen, 12 kilograms of raw material of Chinese medicine of 0.5 kilogram of Colophonium (coarse fodder)
Production method is as follows:
1, the Chinese medicine coarse fodder discards residue after with ethanol extraction, and ethanol extract is concentrated;
2, Colophonium is smashed;
3, Colophonium is gone into a pot heat fused, reenter Oleum Verniciae fordii, Oleum Arachidis hypogaeae semen, when temperature rises to 100 ℃, in pot, spray the ethanol concentrated solution, sprayed and treated no ethanol volatilization in the pot, can be from fire, equitemperature is reduced to about 60 ℃, when plaster becomes to grow paste, according to different specifications the plaster stand is attached on the plaster lining again.
The using method of lead-free plaster: select the plaster of suitable model, directly be attached to affected part or be attached on the corresponding acupoints, when sticking, with hands plaster being sealed two minutes plaster can adsorb, one day or the next day change once.
Claims (6)
1, a kind of lead-free plaster is characterized in that it is is excipient with following vegetable oil, Colophonium, and Chinese medicine is raw material, and ethanol is that medium is made
12 kilograms of raw material of Chinese medicine 1-12 of 1 kilogram of Colophonium of vegetable oil kilogram ethanol 0-100 kilogram
2, lead-free plaster according to claim 1 is characterized in that described raw material of Chinese medicine is clinical applied any prescription.
3, according to claim 1,2 described lead-free plasters, it is characterized in that described raw material of Chinese medicine can be coarse fodder, also can be concentrate, can also have for coarse fodder, both whiles of concentrate.
4, lead-free plaster according to claim 3 is characterized in that said coarse fodder, needs to discard residue with the effective medicinal component of ethanol extraction; Concentrate directly mixes in the plaster.
5, be the plaster that excipient is made according to claim 1,2 described lead-free plasters with vegetable oil, Colophonium, its form approaches the black plaster made with plumbous.
6, according to the preparation method of claim 1,2 or 5 described lead-free plasters, it is characterized in that getting earlier Chinese medicine coarse fodder ethanol extraction, extracting solution concentrates, and again concentrate is ground into superfine powder, Colophonium is smashed, then Colophonium, vegetable oil are put into the iron pan internal heating, and in pot, constantly stir, when temperature reaches 100 ℃ with club, in pot, spray the ethanol extraction concentrated solution, until having sprayed, no ethanol volatilization can treat to throw when the plaster temperature drops to 60 ℃-70 ℃ concentrate from fire again in the pot.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011359099A CN100441167C (en) | 2001-10-17 | 2001-10-17 | Lead free ointment and preparation process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011359099A CN100441167C (en) | 2001-10-17 | 2001-10-17 | Lead free ointment and preparation process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1358496A true CN1358496A (en) | 2002-07-17 |
| CN100441167C CN100441167C (en) | 2008-12-10 |
Family
ID=4673345
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB011359099A Expired - Fee Related CN100441167C (en) | 2001-10-17 | 2001-10-17 | Lead free ointment and preparation process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100441167C (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105769829A (en) * | 2016-05-23 | 2016-07-20 | 宋文宝 | Rosin type lead-free plaster and preparation method thereof |
| CN108653531A (en) * | 2018-05-30 | 2018-10-16 | 湖南众医药咨询有限公司 | A kind of black plaster and preparation method thereof |
| CN109700909A (en) * | 2019-03-19 | 2019-05-03 | 孟召阳 | A kind of preparation method of quick-acting plaster |
-
2001
- 2001-10-17 CN CNB011359099A patent/CN100441167C/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105769829A (en) * | 2016-05-23 | 2016-07-20 | 宋文宝 | Rosin type lead-free plaster and preparation method thereof |
| CN108653531A (en) * | 2018-05-30 | 2018-10-16 | 湖南众医药咨询有限公司 | A kind of black plaster and preparation method thereof |
| CN109700909A (en) * | 2019-03-19 | 2019-05-03 | 孟召阳 | A kind of preparation method of quick-acting plaster |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100441167C (en) | 2008-12-10 |
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Addressee: Xue Hongyang Document name: Notice of first review |
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Granted publication date: 20081210 Termination date: 20091117 |