CN101657325B - 用于色谱分离的具有高有机质含量和增进的孔几何特征的多孔无机/有机混合颗粒 - Google Patents

用于色谱分离的具有高有机质含量和增进的孔几何特征的多孔无机/有机混合颗粒 Download PDF

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CN101657325B
CN101657325B CN2008800056207A CN200880005620A CN101657325B CN 101657325 B CN101657325 B CN 101657325B CN 2008800056207 A CN2008800056207 A CN 2008800056207A CN 200880005620 A CN200880005620 A CN 200880005620A CN 101657325 B CN101657325 B CN 101657325B
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hybrid particles
porous inorganic
particle
organic
organic hybrid
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CN101657325A (zh
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K·D·维恩达姆
J·E·奥加拉
N·L·劳伦斯
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Waters Technologies Corp
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Waters Technologies Corp
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    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/283—Porous sorbents based on silica
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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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CN2008800056207A 2007-02-21 2008-02-21 用于色谱分离的具有高有机质含量和增进的孔几何特征的多孔无机/有机混合颗粒 Expired - Fee Related CN101657325B (zh)

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CN201310499813.5A CN103551132B (zh) 2007-02-21 2008-02-21 用于色谱分离的具有高有机质含量和增进的孔几何特征的多孔无机/有机混合颗粒

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Application Number Priority Date Filing Date Title
US90265507P 2007-02-21 2007-02-21
US60/902,655 2007-02-21
PCT/US2008/002312 WO2008103423A1 (en) 2007-02-21 2008-02-21 Porous inorganic/organic hybrid particles having high organic content and enhanced pore geometry for chromatographic separations

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CN101657325A CN101657325A (zh) 2010-02-24
CN101657325B true CN101657325B (zh) 2013-11-20

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CN201310499813.5A Expired - Fee Related CN103551132B (zh) 2007-02-21 2008-02-21 用于色谱分离的具有高有机质含量和增进的孔几何特征的多孔无机/有机混合颗粒

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US (1) US9120083B2 (enExample)
EP (1) EP2150402A4 (enExample)
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WO (1) WO2008103423A1 (enExample)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6686035B2 (en) 1999-02-05 2004-02-03 Waters Investments Limited Porous inorganic/organic hybrid particles for chromatographic separations and process for their preparation
EP1417366A4 (en) 2001-08-09 2010-10-27 Waters Technologies Corp INORGANIC / ORGANIC HYBRID MONOLITHIC MATERIALS FOR CHROMATOGRAPHIC SEPARATIONS AND PROCESS FOR THEIR PREPARATION
WO2004041398A2 (en) 2002-10-30 2004-05-21 Waters Investments Limited Porous inorganic/organic hybrid materials and preparation thereof
US8658277B2 (en) 2004-07-30 2014-02-25 Waters Technologies Corporation Porous inorganic/organic hybrid materials with ordered domains for chromatographic separations and processes for their preparation
US10773186B2 (en) 2004-07-30 2020-09-15 Waters Technologies Corporation Porous inorganic/organic hybrid materials with ordered domains for chromatographic separations and processes for their preparation
US9440869B2 (en) 2005-09-30 2016-09-13 Abs Materials, Inc. Sol-gel derived compositions
JP2010515804A (ja) 2007-01-12 2010-05-13 ウオーターズ・テクノロジーズ・コーポレイシヨン クロマトグラフ分離用多孔質炭素−ヘテロ原子−ケイ素ハイブリッド無機／有機材料およびその調製のための方法
US20090208542A1 (en) * 2008-02-18 2009-08-20 Conopco, Inc., D/B/A Unilever Product and method for transferring heated flowable cosmetic onto skin
US11439977B2 (en) 2009-06-01 2022-09-13 Waters Technologies Corporation Hybrid material for chromatographic separations comprising a superficially porous core and a surrounding material
EP2437882A4 (en) * 2009-06-01 2016-11-23 Waters Technologies Corp HYBRID MATERIAL FOR CHROMATOGRAPHY SEPARATIONS
US10159911B2 (en) 2009-08-04 2018-12-25 Waters Technologies Corporation High purity chromatographic materials comprising an ionizable modifier
EP2462188A4 (en) * 2009-08-04 2016-11-23 Waters Technologies Corp HIGH-QUALITY CHROMATOGRAPHIC MATERIALS WITH A IONIZABLE MODIFIER
US8975358B2 (en) * 2010-07-23 2015-03-10 The Regents Of The University Of California Compositions and methods for synthesis of organic-silica hybrid materials
US12623205B2 (en) 2010-07-26 2026-05-12 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution
EP3834927B1 (en) 2010-07-26 2026-03-25 Waters Technologies Corporation Method for preparing a superficially porous material
KR20140051373A (ko) * 2011-08-02 2014-04-30 에이비에스 머티리얼즈 인코포레이티드 졸-겔 유래 조성물
CN102503518B (zh) * 2011-11-16 2013-02-13 黑龙江大学 一种多孔晶态TiO2泡沫陶瓷的制备方法
US20150136700A1 (en) 2012-05-15 2015-05-21 Waters Technologies Corporation Chromatographic materials
CN111644164B (zh) * 2012-05-15 2024-03-08 沃特世科技公司 用于分离不饱和分子的色谱材料
US11577179B2 (en) 2013-06-11 2023-02-14 Waters Technologies Corporation Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography
JP6393964B2 (ja) * 2013-07-22 2018-09-26 東ソー株式会社 時間制御による試料注入装置及びそれを備えた液体クロマトグラフィ
US11282688B2 (en) 2015-03-06 2022-03-22 Micromass Uk Limited Spectrometric analysis of microbes
GB2551669B (en) 2015-03-06 2021-04-14 Micromass Ltd Physically guided rapid evaporative ionisation mass spectrometry ("Reims")
US10777397B2 (en) 2015-03-06 2020-09-15 Micromass Uk Limited Inlet instrumentation for ion analyser coupled to rapid evaporative ionisation mass spectrometry (“REIMS”) device
WO2016142693A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited In vivo endoscopic tissue identification tool
WO2016142683A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Improved ionisation of gaseous samples
EP3265821B1 (en) 2015-03-06 2021-06-16 Micromass UK Limited Liquid trap or separator for electrosurgical applications
EP3570315B1 (en) 2015-03-06 2024-01-31 Micromass UK Limited Rapid evaporative ionisation mass spectrometry ("reims") and desorption electrospray ionisation mass spectrometry ("desi-ms") analysis of biopsy samples
CA2981085A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Spectrometric analysis
WO2016142674A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Cell population analysis
CN110706996B (zh) 2015-03-06 2023-08-11 英国质谱公司 用于改进电离的碰撞表面
US11289320B2 (en) 2015-03-06 2022-03-29 Micromass Uk Limited Tissue analysis by mass spectrometry or ion mobility spectrometry
EP3265823B1 (en) 2015-03-06 2020-05-06 Micromass UK Limited Ambient ionization mass spectrometry imaging platform for direct mapping from bulk tissue
US10978284B2 (en) 2015-03-06 2021-04-13 Micromass Uk Limited Imaging guided ambient ionisation mass spectrometry
EP3741303A3 (en) 2015-03-06 2020-12-30 Micromass UK Limited Chemically guided ambient ionisation mass spectrometry
GB201517195D0 (en) 2015-09-29 2015-11-11 Micromass Ltd Capacitively coupled reims technique and optically transparent counter electrode
CN106892937A (zh) * 2015-12-18 2017-06-27 长春工业大学 一种基于苄基的有机钛杂化材料及其制备方法
CN121869327A (zh) 2016-03-06 2026-04-17 沃特世科技公司 用于色谱分离的具有受控孔隙度的多孔材料；其制备方法；以及其用途
WO2017178833A1 (en) 2016-04-14 2017-10-19 Micromass Uk Limited Spectrometric analysis of plants
US10618920B2 (en) * 2016-06-03 2020-04-14 Agilent Technologies, Inc. Functionalized particles having modified phases
EP3491374B1 (en) 2016-07-28 2024-10-09 Waters Technologies Corporation Encapsulated pre-analytic workflow reagents for flow-through devices, liquid chromatography and mass spectrometric analysis
CN107163170A (zh) * 2017-05-31 2017-09-15 宁夏大学 单分散表面多孔的核壳型聚合物色谱介质及其制备方法
US11155575B2 (en) 2018-03-21 2021-10-26 Waters Technologies Corporation Non-antibody high-affinity-based sample preparation, sorbent, devices and methods
WO2020072668A1 (en) 2018-10-02 2020-04-09 Waters Technologies Corporation Sorbents, devices, kits and methods useful for biological sample treatment
CN111426762B (zh) * 2020-03-31 2022-04-12 湖北航天化学技术研究所 一氨基胍硝酸盐和二氨基胍硝酸盐含量的测定方法
US11964874B2 (en) 2020-06-09 2024-04-23 Agilent Technologies, Inc. Etched non-porous particles and method of producing thereof
CN112240917B (zh) * 2020-09-03 2024-09-17 四川科正检测技术有限公司 一种离子色谱仪
WO2022061035A1 (en) 2020-09-16 2022-03-24 Waters Technologies Corporation Improved size exclusion chromatography utilizing low concentration amino acids in size exclusion chromatography mobile phase
CN116209517B (zh) 2020-09-16 2026-06-16 沃特世科技公司 具有羟基封端的peg键合和甲氧基封端的peg表面改性的基于二氧化硅的颗粒
CN117279712B (zh) * 2021-06-29 2026-01-06 株式会社力森诺科 填充剂及其制造方法、以及尺寸排阻色谱用柱
US20230101326A1 (en) * 2021-08-26 2023-03-30 Waters Technologies Corporation Core-shell particles with organic polymer cores
WO2023089538A1 (en) 2021-11-19 2023-05-25 Waters Technologies Corporation A double surface modified porous material with minimized nonspecific interaction
CN118320463A (zh) * 2023-01-12 2024-07-12 安捷伦科技有限公司 用于分离表面活性剂的色谱柱
CN121127312A (zh) 2023-05-05 2025-12-12 沃特世科技公司 用于亲和色谱的蛋白a/g颗粒及其使用方法
EP4613371A1 (en) 2024-03-04 2025-09-10 Dionex Softron GmbH Mixed mode chromatographic packing material
EP4613370A1 (en) 2024-03-04 2025-09-10 Dionex Softron GmbH Mixed mode chromatographic packing material

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5403908A (en) * 1989-10-06 1995-04-04 Idemitsu Kosan Company, Limited Aryl styrene-based copolymer
CN1265691A (zh) * 1997-11-22 2000-09-06 克罗内斯蒂垣两合公司 膦酸硅氧烷处理的无机颗粒

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6686035B2 (en) * 1999-02-05 2004-02-03 Waters Investments Limited Porous inorganic/organic hybrid particles for chromatographic separations and process for their preparation
EP1733786B1 (en) * 1999-02-05 2010-04-14 Waters Technologies Corporation Porous hybrid particles for chromatographic separations
US20060194919A1 (en) * 1999-08-04 2006-08-31 Lichtenhan Joseph D Porosity control with polyhedral oligomeric silsesquioxanes
US6528167B2 (en) * 2001-01-31 2003-03-04 Waters Investments Limited Porous hybrid particles with organic groups removed from the surface
EP1417366A4 (en) * 2001-08-09 2010-10-27 Waters Technologies Corp INORGANIC / ORGANIC HYBRID MONOLITHIC MATERIALS FOR CHROMATOGRAPHIC SEPARATIONS AND PROCESS FOR THEIR PREPARATION
WO2004041398A2 (en) 2002-10-30 2004-05-21 Waters Investments Limited Porous inorganic/organic hybrid materials and preparation thereof
DE112005000269T5 (de) * 2004-02-17 2007-01-25 Waters Investments Ltd., New Castle Poröse Hybridmonolithmaterialien mit von der Oberfläche entfernten organischen Gruppen

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5403908A (en) * 1989-10-06 1995-04-04 Idemitsu Kosan Company, Limited Aryl styrene-based copolymer
CN1265691A (zh) * 1997-11-22 2000-09-06 克罗内斯蒂垣两合公司 膦酸硅氧烷处理的无机颗粒

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CN103551132B (zh) 2017-04-12
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