CN101653497A - Traditional Chinese medical composition for treating calf scour and preparation method thereof - Google Patents
Traditional Chinese medical composition for treating calf scour and preparation method thereof Download PDFInfo
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- CN101653497A CN101653497A CN200910307262A CN200910307262A CN101653497A CN 101653497 A CN101653497 A CN 101653497A CN 200910307262 A CN200910307262 A CN 200910307262A CN 200910307262 A CN200910307262 A CN 200910307262A CN 101653497 A CN101653497 A CN 101653497A
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Abstract
The invention provides a traditional Chinese medical composition for treating calf scour and a preparation method thereof. The traditional Chinese medical composition for treating calf scour is prepared from the following raw materials in parts by weight: 8-15 ebony, 8-15 myrobalam, 3-10 nutmeg, 3-10 opiate shells, 3-10 red halloysite, 3-10 rhizoma atractylodis, 8-15 pencil stone, 3-10 rhizome ofcyrtomium and 3-10 radix scutellariae. The preparation method comprises the following steps: proportionally and accurately weighting and crushing the traditional Chinese medicines; adding water to decoct; taking concentrated filtrate; adding, fully stirring and dissolving ethylparaben, ethanol, propylene glycol and sodium benzoate. The traditional Chinese medical composition has little toxicity and lower cost, effectively takes the effects of preventing and treating the calf scour, enhances the anti-adversity capability of a calf and has obvious effect; and the preparation method is simple, practical and suitable for the need of scaled industrial production.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition and preparation method thereof, especially a kind of Chinese medicine composition for the treatment of calf scour and preparation method thereof.
Background technology
Calf scour, especially calf catch cold, feed and excessively all can cause calf scour, cause the calf dysfunction of spleen and stomach, the defecation increased frequency, even rush down down as water, if treat untimely or malpractice, cause death easily.The Chinese medicine traditional Chinese medical science has long history in China, spread so far with its particular performances, continuous development along with pharmaceuticals industry, Chinese medicine is extracting, application facet has more obtained significant progress, it also highlights more and more important effect in the diseases prevention and treatment of domestic animal, being used for the treatment of at present and preventing the medicine of calf scour still is with Western medicine such as gentamycin, amikacins etc. are main, though Western medicine is being brought into play important function aspect pathogenic the having loose bowels of treatment, but some are got ill from overeating, having loose bowels of causing such as catch cold often is difficult to receive ideal effect with Western medicine, the characteristics that Chinese medicine preparation then has the wholism to control, antibiotic, conditioning, the treating both the principal and secondary aspects of a disease of building up resistance, therefore, a kind of Chinese medicine for the treatment of calf scour of exploitation is significant.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine composition for the treatment of calf scour.
Another technical problem to be solved by this invention is to provide the preparation method of the Chinese medicine composition of above-mentioned treatment calf scour.
For solving the problems of the technologies described above, technical scheme of the present invention is:
A kind of Chinese medicine composition for the treatment of calf scour, form by Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae and Radix Scutellariae, by its parts by weight Fructus Mume 8-15 part, Fructus Chebulae 8-15 part, Semen Myristicae 3-10 part, Pericarpium Papaveris 3-10 part, Halloysitum Rubrum 3-10 part, Rhizoma Atractylodis 3-10 part, Talcum 8-15 part, Rhizoma Osmundae 3-10 part, Radix Scutellariae 3-10 part.
Preferably, the Chinese medicine composition of above-mentioned treatment calf scour is by 12 parts of its parts by weight Fructus Mumes, 12 parts of Fructus Chebulaes, 6 parts of Semen Myristicaes, 6 parts of Pericarpium Papaveriss, 6 parts of Halloysitum Rubrums, 6 parts of Rhizoma Atractylodis, 12 parts in Talcum, 6 parts of Rhizoma Osmundae, 6 parts of Radix Scutellariaes.
Preferably, the Chinese medicine composition of above-mentioned treatment calf scour is by 8 parts of its parts by weight Fructus Mumes, 15 parts of Fructus Chebulaes, 3 parts of Semen Myristicaes, 3 parts of Pericarpium Papaveriss, 10 parts of Halloysitum Rubrums, 3 parts of Rhizoma Atractylodis, 15 parts in Talcum, 10 parts of Rhizoma Osmundae, 3 parts of Radix Scutellariaes.
Preferably, the Chinese medicine composition of above-mentioned treatment calf scour is by 15 parts of its parts by weight Fructus Mumes, 8 parts of Fructus Chebulaes, 10 parts of Semen Myristicaes, 10 parts of Pericarpium Papaveriss, 3 parts of Halloysitum Rubrums, 10 parts of Rhizoma Atractylodis, 8 parts in Talcum, 3 parts of Rhizoma Osmundae, 10 parts of Radix Scutellariaes.
Preferably, the Chinese medicine composition of above-mentioned treatment calf scour is by 10 parts of its parts by weight Fructus Mumes, 11 parts of Fructus Chebulaes, 8 parts of Semen Myristicaes, 8 parts of Pericarpium Papaveriss, 4 parts of Halloysitum Rubrums, 9 parts of Rhizoma Atractylodis, 10 parts in Talcum, 8 parts of Rhizoma Osmundae, 5 parts of Radix Scutellariaes.
Preferably, the Chinese medicine composition of above-mentioned treatment calf scour is by 13 parts of its parts by weight Fructus Mumes, 10 parts of Fructus Chebulaes, 5 parts of Semen Myristicaes, 5 parts of Pericarpium Papaveriss, 7 parts of Halloysitum Rubrums, 4 parts of Rhizoma Atractylodis, 9 parts in Talcum, 9 parts of Rhizoma Osmundae, 8 parts of Radix Scutellariaes.
Preferably, the Chinese medicine composition of above-mentioned treatment calf scour is by 9 parts of its parts by weight Fructus Mumes, 9 parts of Fructus Chebulaes, 4 parts of Semen Myristicaes, 9 parts of Pericarpium Papaveriss, 8 parts of Halloysitum Rubrums, 7 parts of Rhizoma Atractylodis, 14 parts in Talcum, 5 parts of Rhizoma Osmundae, 4 parts of Radix Scutellariaes.
Preferably, the Chinese medicine composition of above-mentioned treatment calf scour is by 11 parts of its parts by weight Fructus Mumes, 13 parts of Fructus Chebulaes, 7 parts of Semen Myristicaes, 7 parts of Pericarpium Papaveriss, 5 parts of Halloysitum Rubrums, 8 parts of Rhizoma Atractylodis, 11 parts in Talcum, 7 parts of Rhizoma Osmundae, 7 parts of Radix Scutellariaes.
Preferably, the Chinese medicine composition of above-mentioned treatment calf scour is by 10 parts of its parts by weight Fructus Mumes, 12 parts of Fructus Chebulaes, 8 parts of Semen Myristicaes, 6 parts of Pericarpium Papaveriss, 10 parts of Halloysitum Rubrums, 8 parts of Rhizoma Atractylodis, 15 parts in Talcum, 5 parts of Rhizoma Osmundae, 6 parts of Radix Scutellariaes.
Preferably, the Chinese medicine composition of above-mentioned treatment calf scour is brown liquid, feeble QI perfume (or spice), sweet in the mouth.
The preparation method of the Chinese medicine composition of above-mentioned treatment calf scour, concrete preparation process is as follows:
(1) getting Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae, Radix Scutellariae respectively is raw material pulverizing, crosses the 60-100 mesh sieve;
(2) get Fructus Mume behind the crushing screening by above-mentioned parts by weight, the Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae, the Radix Scutellariae mix homogeneously, adding the decocting of counting 5～12 times of its gross weights by weight boils, boiled 30～60 minutes, get filtrate, residue adds 5～10 times water boil 30～50 minutes again, get filtrate, leave standstill and be concentrated into relative density 1.0～1.3 after getting supernatant, put into ethanol water afterwards, the concentration expressed in percentage by volume of described ethanol water is 50%～80%, left standstill 24 hours, and got filtrate recycling ethanol and be concentrated into relative density 1.0-1.3;
(3) set by step make the every 190-210ml taking ethylparaben of solution 0.5～2g in (2),, add propylene glycol 5～10ml and stir, add sodium benzoate 0.8～1.2g again and be stirred well to dissolving, add in the described solution, promptly with ethanol 5～15ml dissolving.
Use the Chinese medicine composition of the treatment calf scour that above-mentioned preparation method makes, when the treatment calf scour, gavage by every cattle 200ml, 1 day 2 times, 2～3 days is a course of treatment.
The invention has the beneficial effects as follows:
(1) Chinese medicine composition toxicity of the present invention is little, and cost is lower, can effectively play prevention and therapeutical effect to calf scour, goes back the anti-adversity ability of enhancing body simultaneously, and effect is obvious;
(2) make oral administration solution because of it, directly gavage, ingredient absorbs fast;
(3) described preparation method is simple and easy to do, is fit to requirements of large-scale industrial production.
The specific embodiment
Below in conjunction with specific embodiment technical scheme of the present invention is further described.
Embodiment 1
A kind of Chinese medicine composition for the treatment of calf scour is made up of Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae and Radix Scutellariae, and concrete preparation method is as follows:
(1) getting Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae, Radix Scutellariae respectively is raw material pulverizing, crosses 80 mesh sieves;
(2) get 12 parts of Fructus Mumes behind the crushing screening by weight, 12 parts of Fructus Chebulaes, 6 parts of Semen Myristicaes, 6 parts of Pericarpium Papaveriss, 6 parts of Halloysitum Rubrums, 6 parts of Rhizoma Atractylodis, 12 parts in Talcum, 6 parts of Rhizoma Osmundae, 6 parts of mix homogeneously of Radix Scutellariae, adding the decocting of counting 10 times of its gross weights by weight boils, boiled 60 minutes, get filtrate, residue adds 8 times water boil 30 minutes again, get filtrate, leave standstill and be concentrated into relative density 1.1 after getting supernatant, put into ethanol water afterwards, the concentration expressed in percentage by volume of described ethanol water is 70%, left standstill 24 hours, and got filtrate recycling ethanol and be concentrated into relative density 1.04;
(3) set by step make the every 200ml taking ethylparaben of solution 0.6g in (2),, add propylene glycol 8ml and stir, add sodium benzoate 1.0g again and be stirred well to dissolving, add in the described solution, promptly get oral administration solution with ethanol 10ml dissolving.
Embodiment 2
A kind of Chinese medicine composition for the treatment of calf scour is made up of Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae and Radix Scutellariae, and concrete preparation method is as follows:
(1) getting Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae, Radix Scutellariae respectively is raw material pulverizing, crosses 60 mesh sieves;
(2) get 8 parts of Fructus Mumes behind the crushing screening by weight, 15 parts of Fructus Chebulaes, 3 parts of Semen Myristicaes, 3 parts of Pericarpium Papaveriss, 10 parts of Halloysitum Rubrums, 3 parts of Rhizoma Atractylodis, 15 parts in Talcum, 10 parts of Rhizoma Osmundae, 3 parts of mix homogeneously of Radix Scutellariae, adding the decocting of counting 8 times of its gross weights by weight boils, boiled 45 minutes, get filtrate, residue adds 6 times water boil 30 minutes again, get filtrate, leave standstill and be concentrated into relative density 1.2 after getting supernatant, put into ethanol water afterwards, the concentration expressed in percentage by volume of described ethanol water is 65%, left standstill 24 hours, and got filtrate recycling ethanol and be concentrated into relative density 1.1;
(3) set by step make the every 195ml taking ethylparaben of solution 0.5g in (2),, add propylene glycol 10ml and stir, add sodium benzoate 1.2g again and be stirred well to dissolving, add in the described solution, promptly with ethanol 15ml dissolving.
Embodiment 3
A kind of Chinese medicine composition for the treatment of calf scour is made up of Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae and Radix Scutellariae, and concrete preparation method is as follows:
(1) getting Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae, Radix Scutellariae respectively is raw material pulverizing, crosses 100 mesh sieves;
(2) get 15 parts of Fructus Mumes behind the crushing screening by weight, 8 parts of Fructus Chebulaes, 10 parts of Semen Myristicaes, 10 parts of Pericarpium Papaveriss, 3 parts of Halloysitum Rubrums, 10 parts of Rhizoma Atractylodis, 8 parts in Talcum, 3 parts of Rhizoma Osmundae, 10 parts of mix homogeneously of Radix Scutellariae, adding the decocting of counting 5 times of its gross weights by weight boils, boiled 50 minutes, get filtrate, residue adds 10 times water boil 45 minutes again, get filtrate, leave standstill and be concentrated into relative density 1.15 after getting supernatant, put into ethanol water afterwards, the concentration expressed in percentage by volume of described ethanol water is 60%, left standstill 24 hours, and got filtrate recycling ethanol and be concentrated into relative density 1.0;
(3) set by step make the every 210ml taking ethylparaben of solution 0.8g in (2),, add propylene glycol 5ml and stir, add sodium benzoate 0.8g again and be stirred well to dissolving, add in the described solution, promptly with ethanol 12ml dissolving.
Embodiment 4
A kind of Chinese medicine composition for the treatment of calf scour is made up of Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae and Radix Scutellariae, and concrete preparation method is as follows:
(1) getting Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae, Radix Scutellariae respectively is raw material pulverizing, crosses 80 mesh sieves;
(2) get 10 parts of Fructus Mumes behind the crushing screening by weight, 11 parts of Fructus Chebulaes, 8 parts of Semen Myristicaes, 8 parts of Pericarpium Papaveriss, 4 parts of Halloysitum Rubrums, 9 parts of Rhizoma Atractylodis, 10 parts in Talcum, 8 parts of Rhizoma Osmundae, 5 parts of mix homogeneously of Radix Scutellariae, adding the decocting of counting 12 times of its gross weights by weight boils, boiled 55 minutes, get filtrate, residue adds 5 times water boil 40 minutes again, get filtrate, leave standstill and be concentrated into relative density 1.3 after getting supernatant, put into ethanol water afterwards, the concentration expressed in percentage by volume of described ethanol water is 80%, left standstill 24 hours, and got filtrate recycling ethanol and be concentrated into relative density 1.2;
(3) set by step make the every 190ml taking ethylparaben of solution 1.0g in (2),, add propylene glycol 7ml and stir, add sodium benzoate 1.1g again and be stirred well to dissolving, add in the described solution, promptly get oral administration solution with ethanol 7ml dissolving.
Embodiment 5
A kind of Chinese medicine composition for the treatment of calf scour is made up of Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae and Radix Scutellariae, and concrete preparation method is as follows:
(1) getting Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae, Radix Scutellariae respectively is raw material pulverizing, crosses 100 mesh sieves;
(2) get 13 parts of Fructus Mumes behind the crushing screening by weight, 10 parts of Fructus Chebulaes, 5 parts of Semen Myristicaes, 5 parts of Pericarpium Papaveriss, 7 parts of Halloysitum Rubrums, 4 parts of Rhizoma Atractylodis, 9 parts in Talcum, 9 parts of Rhizoma Osmundae, 8 parts of mix homogeneously of Radix Scutellariae, adding the decocting of counting 6 times of its gross weights by weight boils, boiled 30 minutes, get filtrate, residue adds 9 times water boil 50 minutes again, get filtrate, leave standstill and be concentrated into relative density 1.1 after getting supernatant, put into ethanol water afterwards, the concentration expressed in percentage by volume of described ethanol water is 50%, left standstill 24 hours, and got filtrate recycling ethanol and be concentrated into relative density 1.3;
(3) set by step make the every 210ml taking ethylparaben of solution 2.0g in (2),, add propylene glycol 10ml and stir, add sodium benzoate 1.1g again and be stirred well to dissolving, add in the described solution, promptly with ethanol 15ml dissolving.
Embodiment 6
A kind of Chinese medicine composition for the treatment of calf scour is made up of Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae and Radix Scutellariae, and concrete preparation method is as follows:
(1) getting Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae, Radix Scutellariae respectively is raw material pulverizing, crosses 60 mesh sieves;
(2) get 9 parts of Fructus Mumes behind the crushing screening by weight, 9 parts of Fructus Chebulaes, 4 parts of Semen Myristicaes, 9 parts of Pericarpium Papaveriss, 8 parts of Halloysitum Rubrums, 7 parts of Rhizoma Atractylodis, 14 parts in Talcum, 5 parts of Rhizoma Osmundae, 4 parts of mix homogeneously of Radix Scutellariae, adding the decocting of counting 7 times of its gross weights by weight boils, boiled 45 minutes, get filtrate, residue adds 8 times water boil 40 minutes again, get filtrate, leave standstill and be concentrated into relative density 1.0 after getting supernatant, put into ethanol water afterwards, the concentration expressed in percentage by volume of described ethanol water is 80%, left standstill 24 hours, and got filtrate recycling ethanol and be concentrated into relative density 1.2;
(3) set by step make the every 195ml taking ethylparaben of solution 0.6g in (2),, add propylene glycol 8ml and stir, add sodium benzoate 1.0g again and be stirred well to dissolving, add in the described solution, promptly get oral administration solution with ethanol 5ml dissolving.
Embodiment 7
A kind of Chinese medicine composition for the treatment of calf scour is made up of Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae and Radix Scutellariae, and concrete preparation method is as follows:
(1) getting Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae, Radix Scutellariae respectively is raw material pulverizing, crosses 80 mesh sieves;
(2) get 11 parts of Fructus Mumes behind the crushing screening by weight, 13 parts of Fructus Chebulaes, 7 parts of Semen Myristicaes, 7 parts of Pericarpium Papaveriss, 5 parts of Halloysitum Rubrums, 8 parts of Rhizoma Atractylodis, 11 parts in Talcum, 7 parts of Rhizoma Osmundae, 7 parts of mix homogeneously of Radix Scutellariae, adding the decocting of counting 10 times of its gross weights by weight boils, boiled 45 minutes, get filtrate, residue adds 8 times water boil 30 minutes again, get filtrate, leave standstill and be concentrated into relative density 1.2 after getting supernatant, put into ethanol water afterwards, the concentration expressed in percentage by volume of described ethanol water is 65%, left standstill 24 hours, and got filtrate recycling ethanol and be concentrated into relative density 1.05;
(3) set by step make the every 205ml taking ethylparaben of solution 0.8g in (2),, add propylene glycol 10ml and stir, add sodium benzoate 1.2g again and be stirred well to dissolving, add in the described solution, promptly get oral administration solution with ethanol 12ml dissolving.
Embodiment 8
A kind of Chinese medicine composition for the treatment of calf scour is made up of Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae and Radix Scutellariae, and concrete preparation method is as follows:
(1) getting Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae, Radix Scutellariae respectively is raw material pulverizing, crosses 80 mesh sieves;
(2) get 10 parts of Fructus Mumes behind the crushing screening by weight, 12 parts of Fructus Chebulaes, 8 parts of Semen Myristicaes, 6 parts of Pericarpium Papaveriss, 10 parts of Halloysitum Rubrums, 8 parts of Rhizoma Atractylodis, 15 parts in Talcum, 5 parts of Rhizoma Osmundae, 6 parts of mix homogeneously of Radix Scutellariae, adding the decocting of counting 8 times of its gross weights by weight boils, boiled 60 minutes, get filtrate, residue adds 5 times water boil 45 minutes again, get filtrate, leave standstill and be concentrated into relative density 1.2 after getting supernatant, put into ethanol water afterwards, the concentration expressed in percentage by volume of described ethanol water is 60%, left standstill 24 hours, and got filtrate recycling ethanol and be concentrated into relative density 1.15;
(3) set by step make the every 200ml taking ethylparaben of solution 0.5g in (2),, add propylene glycol 9ml and stir, add sodium benzoate 1.2g again and be stirred well to dissolving, add in the described solution, promptly with ethanol 10ml dissolving.
In the above-mentioned Chinese medicine composition, Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae, Radix Scutellariae all meet the relevant regulations in " Chinese veterinary drug allusion quotation ".
Calf scour mainly is because taste are impaired, causes clear QI failing to ascend, and turbid QI failing to descend mixes together just to become to have loose bowels.The present invention adopts the heart tonifying stomach reinforcing in medication, spleen reinforcing is good for the stomach, the diuretic damp eliminating, the principle that heat-clearing and toxic substances removing etc. combine is carried out prescription and treatment, Fructus Mume in the described Chinese medicine composition, the Fructus Chebulae, Semen Myristicae, Halloysitum Rubrum, Pericarpium Papaveris, the Rhizoma Atractylodis relieving diarrhea with astringents, the relieving restlessness of promoting the production of body fluid, stomach reinforcing nourishes heart, the solid intestinal of spleen reinforcing, warming middle-JIAO to promote flow of QI, invigorating the spleen to clear away damp pathogen is main, the Radix Scutellariae clearing away heat-fire, and the detoxifcation of Rhizoma Osmundae parasite killing is auxilliary, assistant is with the Talcum diuretic, more than all medicines share, emphasize particularly on different fields, mutually Synergistic, in the time of the anti-adversity ability of enhancing body, play spleen reinforcing altogether and be good for the stomach, the damp eliminating cold expelling, clearing away heat and promoting diuresis, the effect of relieving diarrhea with astringents.
Clinical trial 1
In June, 2005, parched rice shop, Zhang Wo town poplar is raised the tolly morbidity at several 5 monthly ages, the main suit: this calf diarrhoea 3 days, not sick just the food, feces Lycoperdon polymorphum Vitt scattered paste shape, feces is the black water sample and the blood streak is arranged after 2 days, poultry is main invalid with the gentamycin intramuscular injection for treating, checks that ill domestic animal body temperature is more than 40.2 ℃, about 108 times/minute of pulse, spirit is depressed, the conjunctiva flushing, the asoscope drying, the xerostomia color is red, and the intestinal sound is faint, the time angry duty arranged.Be diagnosed as diarrhea due to damp-heat,, gavage by every cattle 200ml with embodiment 1 described Chinese medicine composition, one day 2 times, cure rate 91% after 3 days.
Clinical trial 2
In August, 2006, several 3-5 monthly age calf morbidities of Da Feng heap town Wu raising, the main suit: calf diarrhoea continues 2 days, does not eat feces canescence pasty state.Check: body temperature is more than 37.9 ℃, about 70 times/minute of pulse, spirit better, asoscope is moistening, but Cheng Zhu not, abdominal distention, mouthful color is red slightly, thick fur is greasy.Be diagnosed as dyspepsia due to improper feeding and have loose bowels,, gavage, one day 2 times, all cured in 2 days by every cattle 200ml with embodiment 1 described Chinese medicine composition.
As seen, Chinese medicine composition of the present invention is in treatment during calf scour, the stomach reinforcing that nourishes heart, and the solid intestinal of spleen reinforcing, warming middle-JIAO to promote flow of QI, invigorating the spleen to clear away damp pathogen utilizes various component synergism, significantly improves the disease-resistant effect of curing the disease.
Above-mentioned detailed description of this a kind of Chinese medicine composition for the treatment of calf scour and preparation method thereof being carried out with reference to embodiment; be illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (10)
1. Chinese medicine composition for the treatment of calf scour, it is characterized in that: form by Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae and Radix Scutellariae, by its parts by weight Fructus Mume 8-15 part, Fructus Chebulae 8-15 part, Semen Myristicae 3-10 part, Pericarpium Papaveris 3-10 part, Halloysitum Rubrum 3-10 part, Rhizoma Atractylodis 3-10 part, Talcum 8-15 part, Rhizoma Osmundae 3-10 part, Radix Scutellariae 3-10 part.
2. a kind of Chinese medicine composition for the treatment of calf scour according to claim 1 is characterized in that: by 12 parts of its parts by weight Fructus Mumes, 12 parts of Fructus Chebulaes, 6 parts of Semen Myristicaes, 6 parts of Pericarpium Papaveriss, 6 parts of Halloysitum Rubrums, 6 parts of Rhizoma Atractylodis, 12 parts in Talcum, 6 parts of Rhizoma Osmundae, 6 parts of Radix Scutellariaes.
3. a kind of Chinese medicine composition for the treatment of calf scour according to claim 1 is characterized in that: by 8 parts of its parts by weight Fructus Mumes, 15 parts of Fructus Chebulaes, 3 parts of Semen Myristicaes, 3 parts of Pericarpium Papaveriss, 10 parts of Halloysitum Rubrums, 3 parts of Rhizoma Atractylodis, 15 parts in Talcum, 10 parts of Rhizoma Osmundae, 3 parts of Radix Scutellariaes.
4. a kind of Chinese medicine composition for the treatment of calf scour according to claim 1 is characterized in that: by 10 parts of its parts by weight Fructus Mumes, 11 parts of Fructus Chebulaes, 8 parts of Semen Myristicaes, 8 parts of Pericarpium Papaveriss, 4 parts of Halloysitum Rubrums, 9 parts of Rhizoma Atractylodis, 10 parts in Talcum, 8 parts of Rhizoma Osmundae, 5 parts of Radix Scutellariaes.
5. a kind of Chinese medicine composition for the treatment of calf scour according to claim 1 is characterized in that: by 13 parts of its parts by weight Fructus Mumes, 10 parts of Fructus Chebulaes, 5 parts of Semen Myristicaes, 5 parts of Pericarpium Papaveriss, 7 parts of Halloysitum Rubrums, 4 parts of Rhizoma Atractylodis, 9 parts in Talcum, 9 parts of Rhizoma Osmundae, 8 parts of Radix Scutellariaes.
6. a kind of Chinese medicine composition for the treatment of calf scour according to claim 1 is characterized in that: by 9 parts of its parts by weight Fructus Mumes, 9 parts of Fructus Chebulaes, 4 parts of Semen Myristicaes, 9 parts of Pericarpium Papaveriss, 8 parts of Halloysitum Rubrums, 7 parts of Rhizoma Atractylodis, 14 parts in Talcum, 5 parts of Rhizoma Osmundae, 4 parts of Radix Scutellariaes.
7. a kind of Chinese medicine composition for the treatment of calf scour according to claim 1 is characterized in that: by 11 parts of its parts by weight Fructus Mumes, 13 parts of Fructus Chebulaes, 7 parts of Semen Myristicaes, 7 parts of Pericarpium Papaveriss, 5 parts of Halloysitum Rubrums, 8 parts of Rhizoma Atractylodis, 11 parts in Talcum, 7 parts of Rhizoma Osmundae, 7 parts of Radix Scutellariaes.
8. a kind of Chinese medicine composition for the treatment of calf scour according to claim 1 is characterized in that: by 10 parts of its parts by weight Fructus Mumes, 12 parts of Fructus Chebulaes, 8 parts of Semen Myristicaes, 6 parts of Pericarpium Papaveriss, 10 parts of Halloysitum Rubrums, 8 parts of Rhizoma Atractylodis, 15 parts in Talcum, 5 parts of Rhizoma Osmundae, 6 parts of Radix Scutellariaes.
9. according to the described a kind of Chinese medicine composition for the treatment of calf scour of one of claim 1-8, it is characterized in that: be brown liquid, feeble QI perfume (or spice), sweet in the mouth.
10. the preparation method of the Chinese medicine composition of the described treatment calf scour of claim 1-9 is characterized in that: concrete preparation process is as follows:
(1) getting Fructus Mume, Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae, Radix Scutellariae respectively is raw material pulverizing, crosses the 60-100 mesh sieve;
(2) get Fructus Mume behind the crushing screening by above-mentioned parts by weight, the Fructus Chebulae, Semen Myristicae, Pericarpium Papaveris, Halloysitum Rubrum, Rhizoma Atractylodis, Talcum, Rhizoma Osmundae, the Radix Scutellariae mix homogeneously, adding the decocting of counting 5～12 times of its gross weights by weight boils, boiled 30～60 minutes, get filtrate, residue adds 5～10 times water boil 30～50 minutes again, get filtrate, leave standstill and be concentrated into relative density 1.0～1.3 after getting supernatant, put into ethanol water afterwards, the concentration expressed in percentage by volume of described ethanol water is 50%～80%, left standstill 24 hours, and got filtrate recycling ethanol and be concentrated into relative density 1.0-1.3;
(3) set by step make the every 190-210ml taking ethylparaben of solution 0.5～2g in (2),, add propylene glycol 5～10ml and stir, add sodium benzoate 0.8～1.2g again and be stirred well to dissolving, add in the described solution, promptly with ethanol 5～15ml dissolving.
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Application publication date: 20100224 |