CN101647555A - Edible fungus composite nutrient composition for improving cardiovascular and cerebrovascular functions - Google Patents
Edible fungus composite nutrient composition for improving cardiovascular and cerebrovascular functions Download PDFInfo
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Abstract
The invention provides an edible fungus composite nutrient composition for improving cardiovascular and cerebrovascular functions, which integrates edible fungus, plants and Chinese medicines, uses blueberry and black fungus extract as main raw materials and taking qingko, lotus seeds, lotus leaves, cassis seeds, hawthorns and the like as auxiliary materials that are specified by the Ministry of Health of the PRC to be both food and medicine. The composite health care product preparation is formulated by the traditional Chinese medical science theory and the modern nutrology theory,is preparedby scientifically ing and operating an advanced food processing technology and has functions of clearing and activating the channels and collaterals, and improving heart and brain blood-supply deficiency and microcirculation.
Description
Technical field
The present invention relates to nutritional health food field, relate in particular to a kind of compound nutritious composition of edible fungi that improves cardio and vascular function and preparation method thereof.
Background technology
The 21st century people pursue is the food of pure natural, pollution-free, nutrition, health, safety.Particularly pure natural, non agricultural chemical residuum, heavy metal free pollute have nutrition again, the food of health care, safety, extremely consumer's favor.Scientist foretells like this, " 21 century will be the century of pollution-free food ", actual from China, raising along with living standards of the people, the consumer selects the starting point of food, turn to " health " from " simply having adequate food and clothing ", green plants extract " combined food " gains great popularity and becomes inexorable trend.
Be accompanied by the progress of society, work is more and more fierce with the competition of cause, and environmental pollution causes food to be unfavorable for that healthy deposit is more and more.Therefore, cardiovascular and cerebrovascular " inferior health " crowd grows with each passing day, to improve microcirculation, improve cardiac and cerebral blood supply insufficiency, the demand of clearing and activating the channels and collaterals product is in continuous increase, people to high immunity of organisms, improve cardiac and cerebral blood supply insufficiency, improve microcirculatory product and be not content with biochemical series products, especially favor in the health products of plant and Chinese medical extract.Yet present nutraceutical is more, but the overall absorption weak effect, edible not only inconvenience but also influence absorption, and existing processing technology is coarse, can not effectively discharge the ability of the complementation of multiple nutrients material, enriched nutritive effect.Like product is more, but the hill functional food prescription that combines with instant medicine again is few.
The present invention uses traditional Chinese medicine theory and the theoretical prescription of modern medicine nutrition, adopts advanced technologies such as biological enzymolysis wall breaking technology, resin separation purification technology to prepare edible mushroom compound nutritional composite preparation, and product efficacy is definite.
Summary of the invention
The invention provides a kind of compound nutritious composition of edible fungi that improves cardio and vascular function, be that to melt edible mushroom, plant, Chinese medical extract be one, with blueberry, black fungus extract is primary raw material, " not only eat but also medicine " raw material that is aided with health ministry regulation: gingko, lotus seeds, lotus leaf, cassia seed, hawthorn etc., carry out scientific composition according to motherland's Traditional Chinese medical theory and modern nutriology theory: its principle is promoting blood circulation and removing obstruction in channels, mental-tranquilization, and gingko is that its active ingredient of ginkgo has the nutrition of improvement action of the heart; Lotus seeds have the mental-tranquilization effect; Lotus leaf has cool blood effect, and modern study proof lotus leaf has effect for reducing blood fat; Cassia seed has effect for reducing blood fat; Hawthorn has effect for reducing blood fat; Modern study proof blueberry has the immunity of raising, black fungus has effect for reducing blood fat; And the employing refining vegetable oil is an excipients, and refining " compound " that forms of the foods processing technique of uses advanced is clearing and activating the channels and collaterals, improve cardiac and cerebral blood supply insufficiency, improve microcirculatory health food.
Compound nutritious composition of edible fungi of the present invention adopts the raw material of following weight ratio: gingko 500-550 part, lotus seeds 150-200 part, lotus leaf 150-200 part, cassia seed 100-150 part, hawthorn 100-130 part, blueberry 100-150 part, black fungus 100-140 part, refining vegetable oil 380-400 part.
In an embodiment of the present invention, preferred, the weight proportion of described raw material is: 100 parts of gingkoes, 100 parts in lotus seeds, 100 parts on lotus leaf, 100 parts of cassia seeds, 100 parts of hawthorn, 50 parts of blueberries, 50 parts of black fungus, 400 parts of refining vegetable oils.
Described compound nutritious composition of edible fungi can be prepared into suitable clinically preparation according to Chinese medicine preparation.Described preparation comprises capsule, pill, powder, granule, tablet, oral liquid or pill.After for example taking by weighing each bulk drug by described weight portion, pulverize, sieve (for example can be the 200-400 mesh sieve) adds required auxiliary material or the excipients of preparations shaping, is prepared into capsule, powder, tablet or granule.
The present invention also provides a kind of described edible mushroom compound nutritional preparation of compositions method, may further comprise the steps:
(1) big molecule resin separation and purification: pericarp and the seed of getting blueberry, leaching liquor is a 40-50% acetone, and extracting temperature is 50-70 ℃, and extraction time is 50-70 minute, leaching liquor is used the 35-40% ethanol elution after with macroporous resin adsorption, and eluent reclaims and both dusts after ethanol concentrates;
(2) biological enzymolysis broken wall: adopt multi-enzyme method technology, adopt pectase 0.6-1.0%, proteinase-10 .5-0.9%, Ye Huamei 0.3-0.7%, cassia seed, hawthorn are carried out enzymolysis make grain refine, dry back granularity reaches the 100-300 order;
(3) extraction of Blackfungus polyhexose: black fungus powder is broken into meal, crosses the 20-40 mesh sieve, add 10-30 times of water gaging, heating-up temperature is 45-50 ℃, and the proportioning that adds cellulase and pectase is 1-3: 1, and enzymolysis 3-4h; Enzymolysis liquid filters, concentrated spray is drying to obtain Blackfungus polyhexose;
(4) ultramicro grinding: gingko, lotus seeds, lotus leaf are pulverized, and granularity is the 200-400 order;
(5) various compositions that each step of front is prepared and refining vegetable oil and required auxiliary material or the excipients of preparations shaping are prepared into capsule, powder, tablet or granule.
Wherein, the extraction conditions of described blueberry OPC is preferred: extracting temperature is 60 ℃, and extraction time is 60 minutes, and leaching liquor is 50% acetone, and leaching liquor is used 38% ethanol elution after with macroporous resin adsorption.
The extraction of described Blackfungus polyhexose shows by test, and enzymolysis time has the greatest impact to polyoses content, and hydrolysis temperature takes second place, and the influence degree of enzyme proportioning and enzyme dosage is less.Hydrolysis temperature is that 45-50 ℃, enzymolysis time are that the proportioning of 3-4h, enzyme dosage 1.8%, cellulose and pectase is 2: 1 o'clock, and the extraction yield of Blackfungus polyhexose is the highest.
Edible mushroom composite nourishment health care product of the present invention have not only satisfied the modern works and life requirement efficiently, and has guaranteed the nourishing healthy demand of people to blueberry, black fungus.This product has that technology is simple, easy operating, quality stability are easy to control, nutrition accumulation, trophic factors are with strong complementarity, be easy to characteristics such as absorption, taking convenience.
The specific embodiment
The invention will be further described below in conjunction with embodiment, it should be understood that these embodiment only are used for the purpose of illustration, never limit protection scope of the present invention.
Embodiment 1
500 parts of gingkoes, 150 parts in lotus seeds, 200 parts on lotus leaf, 100 parts of cassia seeds, 130 parts of hawthorn, 150 parts of blueberries, 140 parts of black fungus, 400 parts of refining vegetable oils.
(1) big molecule resin separation and purification: the blueberry OPC is that macroreticular resin extracts the blueberry OPC from Daxing'an Mountainrange wild blueberry pericarp and seed, extracting temperature is 60 ℃, extraction time is 60 minutes, leaching liquor is 50% acetone, leaching liquor is used 38% ethanol elution after with macroporous resin adsorption, and eluent reclaims and both dusts after ethanol concentrates;
(2) biological enzymolysis broken wall: adopt multi-enzyme method technology, adopt pectase 0.8%, proteinase-10 .7%, Ye Huamei 0.5%, cassia seed, hawthorn are carried out enzymolysis make grain refine, dry back granularity reaches 200 orders, to raw material yield 10.2-12.4%;
(3) extraction of Blackfungus polyhexose: it is 45-50 ℃ that black fungus powder is broken into that meal crosses 30 mesh sieves, adds 20 times of water gaging heating-up temperatures, and the proportioning that adds cellulase and pectase is 2: 1, and enzymolysis 3-4h, enzymolysis liquid filter, concentrated spray is drying to obtain Blackfungus polyhexose;
(4) ultramicro grinding: gingko, lotus seeds, lotus leaf are pulverized, and granularity is about 300 orders;
(5) the resulting product of abovementioned steps is mixed, it is an amount of to add refining vegetable oil, dextrin, Flos Chrysanthemi total glycosides, and mixing adds ethanol and makes particle in right amount, and low temperature drying is standby;
(6) dried particles with preparation in (5) adopts tablet press machine to carry out compressing tablet, is prepared into tablet.
Embodiment 2
550 parts of gingkoes, 200 parts in lotus seeds, 150 parts on lotus leaf, 150 parts of cassia seeds, 100 parts of hawthorn, 100 parts of blueberries, 100 parts of black fungus, 380 parts of refining vegetable oils.
(1) big molecule resin separation and purification: the blueberry OPC is that macroreticular resin extracts the blueberry OPC from Daxing'an Mountainrange wild blueberry pericarp and seed, extracting temperature is 60 ℃, extraction time is 60 minutes, leaching liquor is 50% acetone, leaching liquor is used 38% ethanol elution after with macroporous resin adsorption, and eluent reclaims and both dusts after ethanol concentrates;
(2) biological enzymolysis broken wall: adopt multi-enzyme method technology, adopt pectase 0.8%, proteinase-10 .7%, Ye Huamei 0.5%, cassia seed, hawthorn are carried out enzymolysis make grain refine, dry back granularity reaches 200 orders, to raw material yield 10.2-12.4%;
(3) extraction of Blackfungus polyhexose: it is 45-50 ℃ that black fungus powder is broken into that meal crosses 30 mesh sieves, adds 20 times of water gaging heating-up temperatures, and the proportioning that adds cellulase and pectase is 2: 1, and enzymolysis 3-4h, enzymolysis liquid filter, concentrated spray is drying to obtain Blackfungus polyhexose;
(4) ultramicro grinding: gingko, lotus seeds, lotus leaf are pulverized, and granularity is about 300 orders;
(5) the resulting product of abovementioned steps is mixed, it is an amount of to add refining vegetable oil, dextrin, Flos Chrysanthemi total glycosides, and mixing adds ethanol and makes particle in right amount, and low temperature drying is standby;
(6) dried particles with preparation in (5) carries out whole grain, is prepared into single-size, after the low temperature drying, and whole grain, packing, promptly.
Embodiment 3
100 parts of gingkoes, 100 parts in lotus seeds, 100 parts on lotus leaf, 100 parts of cassia seeds, 100 parts of hawthorn, 50 parts of blueberries, 50 parts of black fungus, 400 parts of refining vegetable oils.
(1) big molecule resin separation and purification: the blueberry OPC is that macroreticular resin extracts the blueberry OPC from Daxing'an Mountainrange wild blueberry pericarp and seed, extracting temperature is 60 ℃, extraction time is 60 minutes, leaching liquor is 50% acetone, leaching liquor is used 38% ethanol elution after with macroporous resin adsorption, and eluent reclaims and both dusts after ethanol concentrates;
(2) biological enzymolysis broken wall: adopt multi-enzyme method technology, adopt pectase 0.8%, proteinase-10 .7%, Ye Huamei 0.5%, cassia seed, hawthorn are carried out enzymolysis make grain refine, dry back granularity reaches 200 orders, to raw material yield 10.2-12.4%;
(3) extraction of Blackfungus polyhexose: it is 45-50 ℃ that black fungus powder is broken into that meal crosses 30 mesh sieves, adds 20 times of water gaging heating-up temperatures, and the proportioning that adds cellulose and pectase is 2: 1, and enzymolysis 3-4h, enzymolysis liquid filter, concentrated spray is drying to obtain Auricularia polysaccharide.
(4) ultramicro grinding: gingko, lotus seeds, lotus leaf are pulverized, and granularity is about 300 orders;
(5) preparation of suspension: various compositions and refining vegetable oil (purchasing in the soybean oil plant) that each step of front is prepared adopt the suspension making process to prepare suspension;
(6) preparation of soft capsule: with the suspension that makes rotating mould platen press glue ball;
(7) choosing grain: the soft capsule of making is laid on puts into drying alley in shallow, the relative humidity 20%~30%, dry under 21~24 ℃ of air blast conditions of temperature, make glue shell water content in the 6-10% scope, make finished product.
Its every technical indicator of the soft capsule of embodiment 3 has reached every regulation of state food medicine
1, organoleptic indicator
Table 1 organoleptic indicator
Project | Index |
Color and luster | Content is yellow |
Flavour, smell | Has the distinctive taste smell of this product |
Proterties | Soft capsule, complete bright and clean, color and luster are evenly, content is the oily liquids that has particle to suspend |
Impurity | There is not macroscopic exogenous impurity |
2, physical and chemical index
Table 2 physical and chemical index
Project | Index |
Acid value (KOH) mg/g | ??≤3.5 |
Peroxide value (g/100g) | ??≤0.2 |
Ash, % | ??≤5 |
Total arsenic (in As) mg/kg | ??≤1.0 |
Plumbous (in Pb) mg/kg | ??≤1.5 |
Total mercury (in Hg) mg/kg | ??≤0.3 |
BHC, mg/kg | ??≤0.2 |
DDT, mg/kg | ??≤0.2 |
Disintegration time limited, min | ??≤30 |
3, health care
Strengthen immunity function, regulate blood fat, blood pressure, blood sugar, clearing and activating the channels and collaterals, improve cardiac and cerebral blood supply insufficiency, improve microcirculation.
The above only is preferred embodiment of the present invention, only is illustrative for the purpose of the present invention, and nonrestrictive.Those skilled in the art is understood, and can carry out many changes to it in the spirit and scope that claim of the present invention limited, revise, even equivalence, but all will fall within the scope of protection of the present invention.
Claims (9)
1. a compound nutritious composition of edible fungi that improves cardio and vascular function is characterized in that the component that it comprises following weight proportion: gingko 100-150 part, lotus seeds 100-150 part, lotus leaf 100-150 part, cassia seed 100-150 part, hawthorn 100-150 part, blueberry 50-100 part, black fungus 50-100 part, refining vegetable oil 380-400 part.
2. compound nutritious composition of edible fungi according to claim 1 is characterized in that the component that it comprises following weight proportion: 100 parts of gingkoes, 100 parts in lotus seeds, 100 parts on lotus leaf, 100 parts of cassia seeds, 100 parts of hawthorn, 50 parts of blueberries, 50 parts of black fungus, 400 parts of refining vegetable oils.
3. compound nutritious composition of edible fungi according to claim 1 and 2 is characterized in that being prepared into suitable clinically preparation according to Chinese medicine preparation.
4. compound nutritious composition of edible fungi according to claim 3 is characterized in that described preparation comprises capsule, pill, powder, granule, tablet, oral liquid or pill.
5. method for preparing claim 1 or 2 described compound nutritious composition of edible fungi, after it is characterized in that taking by weighing each bulk drug, pulverize, sieve by described weight portion, add required auxiliary material or the excipients of preparations shaping, be prepared into capsule, powder, tablet or granule.
6. method for preparing the described compound nutritious composition of edible fungi of claim 1 is characterized in that may further comprise the steps:
(1) big molecule resin separation and purification: pericarp and the seed of getting blueberry, leaching liquor is a 40-50% acetone, and extracting temperature is 50-70 ℃, and extraction time is 50-70 minute, leaching liquor is used the 35-40% ethanol elution after with macroporous resin adsorption, and eluent reclaims and both dusts after ethanol concentrates;
(2) biological enzymolysis broken wall: adopt multi-enzyme method technology, adopt pectase 0.6-1.0%, proteinase-10 .5-0.9%, Ye Huamei 0.3-0.7%, cassia seed, hawthorn are carried out enzymolysis make grain refine, dry back granularity reaches the 100-300 order;
(3) extraction of Blackfungus polyhexose: black fungus powder is broken into meal, crosses the 20-40 mesh sieve, add 10-30 times of water gaging, heating-up temperature is 45-50 ℃, and the proportioning that adds cellulase and pectase is 1-3: 1, and enzymolysis 3-4h; Enzymolysis liquid filters, concentrated spray is drying to obtain Blackfungus polyhexose;
(4) ultramicro grinding: gingko, lotus seeds, lotus leaf are pulverized, and granularity is the 200-400 order;
(5) various compositions that each step of front is prepared and refining vegetable oil and required auxiliary material or the excipients of preparations shaping are prepared into capsule, powder, tablet or granule.
7. preparation method according to claim 6 is characterized in that the extraction conditions of described blueberry OPC is: extracting temperature is 60 ℃, and extraction time is 60 minutes, and leaching liquor is 50% acetone, and leaching liquor is used 38% ethanol elution after with macroporous resin adsorption.
8. preparation method according to claim 6, the extraction conditions that it is characterized in that described Blackfungus polyhexose is that hydrolysis temperature is that 45-50 ℃, enzymolysis time are that the proportioning of 3-4h, enzyme dosage 1.8%, cellulase and pectase is 2: 1.
9. claim 1 or 2 described compound nutritious composition of edible fungi improve the medicine of cardio and vascular function or the application in the health products in preparation.
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103931792A (en) * | 2014-03-21 | 2014-07-23 | 安徽省怀远县鑫泰粮油有限公司 | Cardiovascular and cerebrovascular disease preventing peanut oil and its preparation method |
CN104000134A (en) * | 2014-04-24 | 2014-08-27 | 安徽金鹰农业科技有限公司 | Brain strengthening and intelligence developing blueberry powder and processing method thereof |
CN108420935A (en) * | 2018-04-26 | 2018-08-21 | 澍林尔(苏州)生物科技有限公司 | A kind of reducing blood pressure and blood fat food medicine |
CN109588703A (en) * | 2018-11-29 | 2019-04-09 | 厦门元之道生物科技有限公司 | A kind of herb fermenting agent of aided blood pressure-lowering and preparation method thereof |
CN111642741A (en) * | 2020-07-17 | 2020-09-11 | 广州同康生物科技有限公司 | Production process of intestinal regulator |
CN113142590A (en) * | 2021-03-24 | 2021-07-23 | 广东丽姿生物科技有限公司 | Composition for improving microcirculation and preparation method thereof |
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103931792A (en) * | 2014-03-21 | 2014-07-23 | 安徽省怀远县鑫泰粮油有限公司 | Cardiovascular and cerebrovascular disease preventing peanut oil and its preparation method |
CN104000134A (en) * | 2014-04-24 | 2014-08-27 | 安徽金鹰农业科技有限公司 | Brain strengthening and intelligence developing blueberry powder and processing method thereof |
CN108420935A (en) * | 2018-04-26 | 2018-08-21 | 澍林尔(苏州)生物科技有限公司 | A kind of reducing blood pressure and blood fat food medicine |
CN109588703A (en) * | 2018-11-29 | 2019-04-09 | 厦门元之道生物科技有限公司 | A kind of herb fermenting agent of aided blood pressure-lowering and preparation method thereof |
CN111642741A (en) * | 2020-07-17 | 2020-09-11 | 广州同康生物科技有限公司 | Production process of intestinal regulator |
CN113142590A (en) * | 2021-03-24 | 2021-07-23 | 广东丽姿生物科技有限公司 | Composition for improving microcirculation and preparation method thereof |
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