CN101647515B - Chinese herbal growth promoter, preparation method and application thereof - Google Patents

Chinese herbal growth promoter, preparation method and application thereof Download PDF

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Publication number
CN101647515B
CN101647515B CN2009100652856A CN200910065285A CN101647515B CN 101647515 B CN101647515 B CN 101647515B CN 2009100652856 A CN2009100652856 A CN 2009100652856A CN 200910065285 A CN200910065285 A CN 200910065285A CN 101647515 B CN101647515 B CN 101647515B
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chinese medicine
percent
powder
growth accelerator
weight
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CN101647515A (en
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吴红云
张谦
郝志友
匡秀华
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Henan Hou Yi Industry Group Co., Ltd.
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Zhengzhou Houyi Pharmaceutical Co Ltd
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

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Abstract

The invention relates to a Chinese herbal growth promoter, a preparation method and an application thereof, belonging to the technical field of animal feed. The Chinese herbal growth promoter comprises the active ingredients prepared from the following raw materials in proportion by weight: 1-5 percent of rhizoma dryopteris crassirhizomae, 0.5-4 percent of radix polygoni multiflori preparata, 10-60 percent of malt, 30-70 percent of fried bean, 2-4 percent of astragalus root, 1.5-8 percent of Chinese angelica, 0.5-5 percent of dried orange peel, 0.5-4 percent of hawthorn and 0.5-4 percent of betel nut. The Chinese herbal growth promoter for animals can obviously improve the growth speed of animals, the feed conversion ratio and the feed returns and reduce the feed cost. The invention has the advantages of cheap and easily obtained raw materials, simple and reasonable preparation method, high safety and efficiency and convenient popularization.

Description

A kind of Chinese medicine growth accelerator and preparation and application
(1) technical field
The invention belongs to technical field of animal, particularly a kind of Chinese medicine growth accelerator and preparation and application.
(2) background technology
Along with the raising of Developing of Animal Industry and living standards of the people, people by the stress quantity to the neglect of quality weight heavy again that turns to, have had requirements at the higher level to the residual amount of its medicine, hygienic quality etc. to the demand of animal food.
Worldwide, antibiotics promptly begins to be used as growth accelerator in Production of Livestock and Poultry from the 1950's.Undoubtedly, use antibiotics to improve the growth rate of livestock and poultry and the effect of growth efficiency is confirmed by a large amount of research institutes.The antibiotics growth accelerator plays a role by regulating gut flora, is subjected to most gram positive bacterias of its effect to influence animal health and production performance.Present science data clearly show that Antibiotic Additive bringing into play important effect in modern animal produces.But the researcher finds feeding antibiotic and can cause that resistant micro-organism significantly increases in the enteron aisle, causes those that one or more antiseptics are produced chemical sproof flora to the inhibition of specific antiseptic and optionally grows.In addition, selection course can make bacterial antibiotic produce widely inhibition at double.Observation to this process has increased use the worry of antibiotic to human disease treatment indiscriminately.This has just caused a worry: antibiotic effect when continue using certain antibiotic to cause drug-fast bacteria propagation can influence the treatment people obtaining disease as growth promoter in livestock and poultry.Thereby, in feed, add antibiotic for a long time in large quantities, directly threatened health, antibiotic will reduce in livestock and poultry gradually, until thorough forbidding.Given this, Sweden thoroughly forbade antibiotic as the use of feed addictive in the herding industry in 1986, and Denmark forbids avoparcin and VIRGINIAMYCIN respectively in nineteen ninety-five and 1998, and European Union forbade avoparcin in 1997.Rose in 1999, European Union has only 4 kinds of antibiotic can use on the basis of " careful using priciple ", is bacitracin, acetyl spiramycin, tylosin and VIRGINIAMYCIN.
Be devoted to thoroughly to forbid antibiotic as the use of growth accelerator though comprise states such as China and America and Europe in the herding industry,, can substitute before antibiotic produces as the preparation of growth accelerator new, it will use in quite long period.Therefore, seek the critical work that this " substituting preparation " just becomes various countries scientific worker and veterinary drug manufacturing enterprise.
Chinese herb feed additive with its have no side effect, do not have hazard residue, advantage such as have no drug resistance, be subjected to domestic and international experts and scholars in recent years and pay close attention to, it will become one of substitute of antibiotics growth accelerator.The use of Chinese herbal medicine gets according to empiric observation, and it can produce useful effect.It has specific non-oxidizability, antibiotic property, immunity regulating type and appetite control characteristic.Big quantity research clearlys show, some Chinese herbal medicine can produce significant benefits aspect the breeding performonce fo animals influencing.So far, also there have been many Chinese herbal medicine growth promoter products to occur, also included some Chinese herbal medicine growth promotion preparations in " People's Republic of China's veterinary drug allusion quotation ".Proved the definite effect of Chinese herbal medicine growth promoter.
But the present situation of Chinese herbal medicine class growth accelerator is at present, adopts Chinese herbal medicine directly to pulverize mostly and is used as medicine with powder, and formulation is single; Feeding volume is excessive, uses inconvenience; Being easy to change daily ration forms; The storage and transport cost height; Useless composition proportion is too big, and effect is had a greatly reduced quality; Difficult quality control.
(3) summary of the invention
The object of the present invention is to provide agent of a kind of Chinese medicine promoting animal growth and preparation thereof and application; Described Chinese medicine growth accelerator is nuisanceless, and the high addition of active constituent content is little; Be convenient to the transportation, quality be easy to control.
The technical solution used in the present invention is as follows:
A kind of Chinese medicine growth accelerator, its active ingredient is made by the raw material of following weight ratio example: thick wood-fern rhizome 1~5%, baked polygonum capitatum 0.5~4%, Fructus Hordei Germinatus 10~60%, stir-bake to yellowish beans 30~70%, the Radix Astragali 2~4%, Radix Angelicae Sinensis 1.5~8%, dried orange peel 0.5~5%, hawthorn 0.5~4%, betel nut 0.5~4%.
Described Chinese medicine growth accelerator is a powder.
Described Chinese medicine growth accelerator can be prepared according to conventional method, but preferably carries out according to following method: at first get each raw material according to described part by weight, step is as follows afterwards:
1) with the Radix Astragali, Radix Angelicae Sinensis, dried orange peel, hawthorn, betel nut boiling 3 times, merges decocting liquid, filter, be concentrated into the thick paste shape;
2) thick wood-fern rhizome, baked polygonum capitatum, Fructus Hordei Germinatus, stir-bake to yellowish beans are mixed, pulverize, cross the 50-80 mesh sieve;
3) get thick paste in the step 1) and weight be thick paste weight 3-6 doubly 2) in evenly 50-80 ℃ of oven dry in back of powder, pulverized the 50-80 mesh sieve once more, powder;
4) with step 2) in remaining powder and 3) in powder evenly promptly get described Chinese medicine growth accelerator.
Described Chinese medicine growth accelerator is used to promote the growth of pig; Described Chinese medicine growth accelerator adds according to the 0.1-1.0% of original medicinal material weight meter with feed weight.
The application of described Chinese medicine growth accelerator in preparation treatment pig endoparasite, poor appetite or dyspeptic medicine.
Chinese medicine growth accelerator of the present invention is a kind of veterinary formulations, and said preparation can be admixed in the feed and feed, and also can add to feed after drinking-water stirs.The effect of each material is as follows in the preparation raw materials of effective components: thick wood-fern rhizome, and clearing heat and detoxicating, expelling parasite; The moxibustion tuber of multiflower knotweed: filling liver kidney, benefiting essence-blood, strengthening the bones and muscles; Fructus Hordei Germinatus: promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite; The stir-bake to yellowish beans: nutritious, can replenish the necessary amino acid in the body; The Radix Astragali: invigorating qi for strengthening superficies, diuresis holder poison, apocenosis, expelling pus and promoting granulation.Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, relax bowel.Dried orange peel: regulating qi-flowing for strengthening spleen, eliminating dampness and eliminating phlegm, sharp water defaecation.Hawthorn: appetite-stimulating indigestion-relieving, long-pending, promoting blood circulation to remove blood stasis, the promoting the circulation of qi of reducing phlegm of disappearing change to stagnate.Betel nut: the effect that desinsection, broken long-pending, the therapeutic method to keep the adverse qi flowing downward, row water are arranged.After each Chinese medicine cooperated, the preparation that contains its active ingredient that makes had that tonifying Qi is enriched blood, regulating qi-flowing for strengthening spleen, helping digestion disappear long-pending function, thereby built up health, and accelerated weightening finish.
This invention is not added any antibiotic, and is used as medicine with the extracting section thing of Chinese medicine because its active ingredient is pure Chinese medicinal preparation, therefore can reduce dose, reduces feedstuff-meat ratio, improves taste, and improves bioavailability of medicament.
The present invention has following advantage with respect to prior art:
The agent of described Chinese medicine promoting animal growth can significantly improve the speed of growth of animal, and can significantly improve feedstuff-meat ratio, improves the price of deed, reduces feeding cost.Raw material of the present invention is cheap and easy to get, the preparation method is simple, rationally, safe and efficient, be convenient to promote.
(4) specific embodiment:
Below with specific embodiment technical scheme of the present invention is described, but protection scope of the present invention is not limited thereto:
Embodiment 1
The Chinese medicine growth accelerator, it is made by following raw materials according:
Thick wood-fern rhizome 30g, baked polygonum capitatum 30g, Fructus Hordei Germinatus 500g, stir-bake to yellowish beans 500g, Radix Astragali 30g, Radix Angelicae Sinensis 30g, dried orange peel 30g, hawthorn 30g, betel nut 30g
A, the Radix Astragali, Radix Angelicae Sinensis, dried orange peel, hawthorn, betel nut are added 8 times of water gagings, soak after 30 minutes, decoct 3 times, kept 1.5 hours after each boiling, collecting decoction also is concentrated into the thick paste shape;
B, thick wood-fern rhizome, baked polygonum capitatum, Fructus Hordei Germinatus, stir-bake to yellowish beans are mixed, pulverize, powder;
C, be that powder is even described in its b of 3 times with thick paste described in the step a and weight, 80 ℃ of oven dry are down pulverized again, powder;
D, powder described in powder described in the step c and the remaining b is merged, mix, cross 50 mesh sieves, packing promptly gets Chinese medicine promoting animal growth of the present invention agent.
Embodiment 2
Prescription: thick wood-fern rhizome 60g, baked polygonum capitatum 45g, Fructus Hordei Germinatus 270g, stir-bake to yellowish beans 550g, Radix Astragali 45g, Radix Angelicae Sinensis 90g, dried orange peel 60g, hawthorn 45g, betel nut 45g.
A, the Radix Astragali, Radix Angelicae Sinensis, dried orange peel, hawthorn, betel nut are added 8 times of water gagings, soak after 30 minutes, decoct 3 times, kept 1.5 hours after each boiling, collecting decoction also is concentrated into the thick paste shape;
B, thick wood-fern rhizome, baked polygonum capitatum, Fructus Hordei Germinatus, stir-bake to yellowish beans are mixed, pulverize, powder;
C, thick paste described in the step a is added weight be described in its b of 4 times in the powder, mixes, and 70 ℃ of oven dry are down pulverized again, get powder;
D, powder described in powder described in the step c and the remaining b is merged, mix, cross 50 mesh sieves, packing promptly gets Chinese medicine promoting animal growth of the present invention agent.
Embodiment 3
Prescription: thick wood-fern rhizome 24g, baked polygonum capitatum 36g, Fructus Hordei Germinatus 242g, stir-bake to yellowish beans 847g, Radix Astragali 24g, Radix Angelicae Sinensis 20g, dried orange peel 6g, hawthorn 6g, betel nut 6g
A, the Radix Astragali, Radix Angelicae Sinensis, dried orange peel, hawthorn, betel nut are added 8 times of water gagings, soak after 30 minutes, decoct 3 times, kept 1.5 hours after each boiling, collecting decoction also is concentrated into the thick paste shape;
B, thick wood-fern rhizome, baked polygonum capitatum, Fructus Hordei Germinatus, stir-bake to yellowish beans are mixed, pulverize, powder;
C, thick paste described in the step a is added weight be described in its b of 5 times in the powder, mixes, and 65 ℃ of oven dry are down pulverized again, get powder;
D, powder described in powder described in the step c and the remaining b is merged, mix, cross 50 mesh sieves, packing promptly gets Chinese medicine promoting animal growth of the present invention agent.
Embodiment 4
Prescription: thick wood-fern rhizome 48g, baked polygonum capitatum 36g, Fructus Hordei Germinatus 470g, stir-bake to yellowish beans 470g, Radix Astragali 36g, Radix Angelicae Sinensis 72g, dried orange peel 36g, hawthorn 36g, betel nut 36g.
A, the Radix Astragali, Radix Angelicae Sinensis, dried orange peel, hawthorn, betel nut are added 8 times of water gagings, soak after 30 minutes, decoct 3 times, kept 1.5 hours after each boiling, collecting decoction also is concentrated into the thick paste shape;
B, thick wood-fern rhizome, baked polygonum capitatum, Fructus Hordei Germinatus, stir-bake to yellowish beans are mixed, pulverize, powder;
C, thick paste described in the step a is added weight be described in its b of 6 times in the powder, mixes, and 60 ℃ of oven dry are down pulverized again, get powder;
D, powder described in powder described in the step c and the remaining b is merged, mix, cross 50 mesh sieves, packing promptly gets Chinese medicine promoting animal growth of the present invention agent.
Embodiment 5
Prescription: thick wood-fern rhizome 25g, baked polygonum capitatum 40g, Fructus Hordei Germinatus 240g, stir-bake to yellowish beans 715g, Radix Astragali 30g, Radix Angelicae Sinensis 85g, dried orange peel 25g, hawthorn 36g, betel nut 12g.
A, the Radix Astragali, Radix Angelicae Sinensis, dried orange peel, hawthorn, betel nut are added 8 times of water gagings, soak after 30 minutes, decoct 3 times, kept 1.5 hours after each boiling, collecting decoction also is concentrated into the thick paste shape;
B, thick wood-fern rhizome, baked polygonum capitatum, Fructus Hordei Germinatus, stir-bake to yellowish beans are mixed, pulverize, powder;
C, thick paste described in the step a is added weight be described in its b of 5 times in the powder, and after mixing, 50 ℃ of oven dry are down pulverized again, get powder;
D, powder described in powder described in the step c and the remaining b is merged, mix, cross 50 mesh sieves, packing promptly gets Chinese medicine promoting animal growth of the present invention agent.
The weightening finish experiment:
1 materials and methods
1.1 experimental animal and test period
40 piglets of about 20kg (long white) are selected in test for use, and sex is regardless of, and is divided into 2 groups at random, i.e. test group and control group, and every group each 20, after conventional immunity and expelling parasite, observation 7d (clinical health) enters experimental period then, and test period is 30 days.
1.2 trial drug and adding method
The embodiment of the invention 1 medicine is made an addition in the test group feed in feed weight 0.5% (in crude drug weight) ratio, stir, control group does not add any medicine.
1.3 experimental basis daily ration
The experimental basis daily ration is commercially available complete feed, purchases in Henan Lianhe Inve Feed Co., Ltd..
1.4 test method
Test group and control group are except that adding medicine, and it is all identical that each organizes basal diet, colony house condition, management etc., throws something and feeds every day 3~4 times, and free choice feeding is freely drunk water, and when on-test and end, weigh on an empty stomach by head, calculate average daily gain, feed consumption and material anharmonic ratio.
2 test results and analysis
Table 1 gaining effect relatively
Figure G2009100652856D00061
2.1 weightening finish
As shown in Table 1, the equal daily gain of test group head is 680.55g, and the equal daily gain of control group head is 615.35g, and test group improves 10.6% than control group.
2.2 feedstuff-meat ratio
As can be seen from Table 1, test group and control group feedstuff-meat ratio are respectively 2.66: 1 and 2.81: 1, and test group improves 5.34% than control group.
Test shows that the present invention makes an addition in proportion can improve piglet appetite in the piglet diet, increase feed intake, significantly increases the growth rate of test group pig, and can significantly improve feedstuff-meat ratio, improves the price of deed, reduces feeding cost.Raw material of the present invention is cheap and easy to get, safe and efficient, is convenient to promote.

Claims (6)

1. Chinese medicine growth accelerator, it is characterized in that, its active ingredient is made by the raw material of following weight ratio example: thick wood-fern rhizome 1~5%, baked polygonum capitatum 0.5~4%, Fructus Hordei Germinatus 10~60%, stir-bake to yellowish beans 30~70%, the Radix Astragali 2~4%, Radix Angelicae Sinensis 1.5~8%, dried orange peel 0.5~5%, hawthorn 0.5~4%, betel nut 0.5~4%.
2. Chinese medicine growth accelerator as claimed in claim 1 is characterized in that, described Chinese medicine growth accelerator is a powder.
3. the preparation method of the described Chinese medicine growth accelerator of claim 1 is characterized in that, gets each raw material according to described part by weight, and step is as follows afterwards:
1) with the Radix Astragali, Radix Angelicae Sinensis, dried orange peel, hawthorn and betel nut boiling 3 times, merges decocting liquid, filter, be concentrated into the thick paste shape;
2) thick wood-fern rhizome, baked polygonum capitatum, Fructus Hordei Germinatus, stir-bake to yellowish beans are mixed, pulverize, cross the 50-80 mesh sieve;
3) get thick paste in the step 1) and weight be thick paste weight 3-6 doubly 2) in evenly 50~80 ℃ of oven dry in back of powder, pulverized the 50-80 mesh sieve once more, powder;
4) with step 2) in remaining powder and 3) in powder evenly promptly get described Chinese medicine growth accelerator.
4. the application of the described Chinese medicine growth accelerator of claim 1 in the growth that promotes pig.
5. the application of Chinese medicine growth accelerator as claimed in claim 4 in the growth that promotes pig is characterized in that, described Chinese medicine growth accelerator adds according to the 0.1-1.0% of original medicinal material weight meter with feed weight.
6. the application of the described Chinese medicine growth accelerator of claim 1 in preparation treatment pig endoparasite, poor appetite or dyspeptic medicine.
CN2009100652856A 2009-06-26 2009-06-26 Chinese herbal growth promoter, preparation method and application thereof Expired - Fee Related CN101647515B (en)

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CN102754734B (en) * 2012-05-28 2013-06-19 鲁东大学 Chinese herbal livestock feed additive and application thereof
CN102727693B (en) * 2012-06-20 2014-01-01 青岛绿曼生物工程有限公司 Compound propolis composition used for treating swine toxoplasmosis, and preparation method thereof
CN104161177B (en) * 2013-07-15 2016-06-08 河南联合英伟饲料有限公司 A kind of promote pig growth and improve the Chinese herbal feed additive of meat
CN103829108B (en) * 2014-03-26 2015-08-12 山东新希望六和集团有限公司 Promote Chinese medicine additive of piglet growth and preparation method thereof
CN104474438A (en) * 2014-11-26 2015-04-01 郑州后羿制药有限公司 Traditional Chinese medicine composition for promoting pig growth and improving pork quality
CN104435907A (en) * 2014-12-29 2015-03-25 河南天纳图生物科技有限公司 Compound fermented Chinese medicine for livestock fattening and preparation method of compound fermented Chinese medicine
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CN106376742A (en) * 2016-08-29 2017-02-08 天峨县全盛蜂业科技有限公司 Pig traditional Chinese medicine feed additive for growth promotion
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