CN101617664A - Sterilization composite containing cyprodinil and epoxiconazole - Google Patents
Sterilization composite containing cyprodinil and epoxiconazole Download PDFInfo
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- CN101617664A CN101617664A CN200910023209A CN200910023209A CN101617664A CN 101617664 A CN101617664 A CN 101617664A CN 200910023209 A CN200910023209 A CN 200910023209A CN 200910023209 A CN200910023209 A CN 200910023209A CN 101617664 A CN101617664 A CN 101617664A
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- cyprodinil
- ring azoles
- fluorine ring
- epoxiconazole
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Abstract
The invention discloses a sterilization composite containing cyprodinil and epoxiconazole whose effective activity components comprise cyprodinil and epoxiconazole in a weight ratio of 10-80:50-1. Auxiliary agent and excipient are added into the effective activity components to prepare wettability powder, water-dispersion granule and suspending agent. The invention is used for curing and preventing diseases of fruit trees and grains, and has obvious synergized effect in preventing and curing sigatoka, apple tree alternaria leaf spot, and wheat powdery mildew.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of contain cyprodinil and the composite application of bactericidal composition on fruit tree and cereal disease of fluorine ring azoles.
Technical background
Cyprodinil (cyprodinil) is that pure product are powdery solid by the aminopyrimidine bactericide of Syngenta Co.,Ltd's exploitation.Molecular formula: C
14H
15N
3, chemical name: 4-cyclopropyl-6-methyl-N-phenyl pyrimidine-2-amine.
Cyprodinil is the methionine biosynthesis inhibitor.No cross resistances such as same triazole type, imidazoles, morpholine class, phenylpyrrole class.The main mode of action of cyprodinil is to suppress the biosynthesis of methionine moral, suppresses the secretion of hydrolase.Absorbed rapidly by blade in plant corpus, be penetrated into more than 30% in the tissue, protected sediment is stored in the blade; transmit in xylem, also transmit between blade, metabolism at high temperature is rapid relatively; sediment quite stable under the low temperature in blade, metabolite inanimate object activity.Be mainly used in the gray mold, powdery mildew, scab of control wheat, barley, grape, strawberry, fruit tree, vegetables, ornamental plants etc. etc.
Fluorine ring azoles (epoxiconazole) is the triazole bactericidal agent by BASF AG's exploitation, molecular formula C
17H
13ClFN
3O, chemical name: (2RS, 3SR)-3-(2-chlorphenyl)-2-(4-fluorophenyl)-2-[(1H1,2, the 4-triazol-1-yl) methyl] oxirane.
Fluorine ring azoles is a kind of triazole type wide-spectrum bactericide, belongs to C-14 demethylation enzyme inhibitor in the biosynthesis of cell membrane sterol.Have protection and therapeutic action concurrently.Be mainly used in the disease of control cereal crop, rape, lawn, coffee, paddy rice and fruit tree etc.Field test results shows that it has good preventive and therapeutic effect to ten multiple diseases such as a series of cereal class corps diseases such as damping off, powdery mildew, eyeprint diseases, and can prevent and treat the disease in sugar beet, peanut, rape, lawn, coffee, paddy rice and the fruit tree etc.Good protection not only there is, treats and roots out activity, and inhale and preferable residual activity in having.
In the real process of agricultural production, preventing and treating the problem that disease is easy to generate most is the drug-fast generation of germ.Important disease such as powdery mildew, spot defoliation, leaf spot etc. are because its spread speed is fast on the agricultural, and host range is wide, often takes place in the plant growth later stage, is easy to generate resistance especially.In some diseases serious place takes place, use such as common bactericide such as tpn, thiophanate-methyl, tmtd etc. have not separately had any effect.Fluorine ring azoles, cyprodinil etc. have also caused very serious resistance, and have been easy to generate poisoning owing to large-area application.At present, adopt composite bactericidal composition can obviously improve control and result of treatment, reduced the usage amount of agricultural chemicals, reduced cost, become the important means of the various diseases of integrated control.
So far do not see the relevant report of relevant cyprodinil and the composite product of fluorine ring azoles on domestic and international magazine and the related media as yet.
Summary of the invention
The purpose of this invention is to provide the bactericidal composition that contains cyprodinil and fluorine ring azoles that a kind of antagonism germ has synergistic effect.
The present invention is achieved through the following technical solutions:
The bactericidal composition that contains cyprodinil and fluorine ring azoles, cyprodinil and fluorine ring azoles percentage by weight are 10～80: 50～1, percentage by weight after wherein preferred is 10～70: 30～5, effective active composition weight percentage is 11% to 80%, adds auxiliary agent and excipients and makes wetting powder, water dispersible granules, suspending agent.
When making wetting powder, composition comprises following constituent content: cyprodinil 10～80%, fluorine ring azoles 1～50%, dispersant 3～15%, wetting agent 2～12%, filler 5～84%.
Cyprodinil, fluorine ring azoles, dispersant, wetting agent, filler are mixed in mixed cylinder, after airslide disintegrating mill is pulverized, mix again, promptly can be made into cyprodinil fluorine ring azoles wetting powder.
When making water dispersible granules, composition comprises following constituent content: cyprodinil 10～80%, fluorine ring azoles 1～50%, dispersant 3～12%, wetting agent 2～8%, disintegrant 0～8%, binding agent 0～5%, filler 5～84%.
Cyprodinil, fluorine ring azoles, dispersant, wetting agent, disintegrant, filler etc. are obtained the particle diameter that needs through comminution by gas stream together, add other auxiliary agents such as binding agent again, obtain the materials of granulating.It is interior through after granulation and the drying to expect that product are quantitatively sent the fluidized bed granulation dryer to, makes cyprodinil epoxiconazole water dispersant product.
When making suspending agent, composition comprises following constituent content: cyprodinil 10～50%, fluorine ring azoles 1～20%, dispersant 3～12%, wetting agent 2～10%, defoamer 0.1～0.5%, thickener 0～2%, antifreeze 0～8%, deionized water surplus.
Dispersant, wetting agent, defoamer, thickener, antifreeze in the above-mentioned formulation material are mixed through high speed shear, add cyprodinil, fluorine ring azoles, ball milling is 2～3 hours in ball mill, makes diameter of particle all below 5 μ m, makes cyprodinil epoxiconazole suspension concentrate product.
Described dispersant is selected from one or more in polycarboxylate, lignosulfonates, alkylphenol polyoxyethylene formaldehyde condensation products sulphate, alkyl benzene sulfonate calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol polyoxyethylene, aliphatic amine polyoxyethylene ether, polyoxyethylene carboxylate, the fatty acid glyceride APEO.
Described wetting agent is natural products wetting agent and cationic wetting agent, and available tea is withered, spaonin powder, silkworm excrement, soapberry powder, bay alcohol radical sodium sulphate, lauryl sodium sulfate, neopelex, washing powder, draw back in the powder one or more.
Described disintegrant is selected from one or more in bentonite, ammonium sulfate, calcium chloride, urea, magnesium chloride, aluminium chloride, citric acid, succinic acid, the carbonic hydroammonium.
Described defoamer is selected from one or more in silicone oil, silicone compound, C10-20 saturated fat acid compounds, the C8-10 aliphatic alcohols compound.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, the glycerine.
Described binding agent is selected from: one or more in gum Arabic, white dextrin, carboxy-propyl cellulose, xanthan gum, methylcellulose, PAA, polyvinylpyrrolidone, crospolyvinylpyrrolidone, polyethylene glycol, polyvinyl alcohol, anhydrous succinic acid-styrene copolymerized, the polyvinyl acetate.
Described thickener is selected from: one or more in xanthans, CMC, hydroxyethylcellulose, methylcellulose, Magnesiumaluminumsilicate, polyvinyl alcohol, the polyethylene glycol.
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate.
Described bactericidal composition is used to prevent and treat the disease on fruit tree and the cereal, is mainly used in to prevent and treat sigatoka, alternaria leaf spot of apple, wheat powdery mildew.
The invention has the advantages that: (1) cyprodinil has the different mechanisms of action with fluorine ring azoles, mutual composite no antagonism; The agricultural chemicals of (2) two kinds of different mechanisms of action carries out composite, has both enlarged fungicidal spectrum, has saved production cost again; (3) composition does not contain organic solvent, and environmental pollution is little, and use cost is low; (4) be used to prevent and treat sigatoka, alternaria leaf spot of apple, wheat powdery mildew and have good synergistic effect.
Embodiment
To further instruction of the present invention, but the scope of application of the present invention is not limited to following illustrated embodiment below in conjunction with embodiment.
Embodiment 1 80% cyprodinil fluorine ring azoles wetting powder
Cyprodinil 55%, fluorine ring azoles 25%, polycarboxylate 3%, lauryl sodium sulfate 4%, white carbon 4%, kaolin 9%, mixture carries out comminution by gas stream, makes 80% cyprodinil fluorine ring azoles wetting powder.
Embodiment 2 62% cyprodinil fluorine ring azoles wetting powders
Cyprodinil 42%, fluorine ring azoles 20%, alkyl benzene sulfonate calcium salt 4%, washing powder 4%, diatomite 30%, mixture carries out comminution by gas stream, makes 62% cyprodinil fluorine ring azoles wetting powder.
Embodiment 3 40% cyprodinil fluorine ring azoles wetting powders
Withered 3%, the kaolin 53% of cyprodinil 32%, fluorine ring azoles 8%, aliphatic amine polyoxyethylene ether 4%, tea, mixture carries out comminution by gas stream, makes 40% cyprodinil fluorine ring azoles wetting powder.
Embodiment 4 80% cyprodinil epoxiconazole water dispersants
Cyprodinil 60%, fluorine ring azoles 20%, polycarboxylate 4%, neopelex 3%, urea 2%, starch 11% make 80% cyprodinil epoxiconazole water dispersant.
Embodiment 5 60% cyprodinil epoxiconazole water dispersants
Cyprodinil 45%, fluorine ring azoles 15%, alkylphenol polyoxyethylene 4%, neopelex 3%, magnesium chloride 2%, starch 10%, bentonite 21% make 60% cyprodinil epoxiconazole water dispersant.
Embodiment 6 45% cyprodinil epoxiconazole water dispersants
Cyprodinil 33%, fluorine ring azoles 12%, lignosulfonates 3%, spaonin powder 4%, calcium chloride 3%, starch 10%, kaolin 35%, the mixed 45% cyprodinil epoxiconazole water dispersant that gets.
Embodiment 7 50% cyprodinil epoxiconazole suspension concentrates
Cyprodinil 40%, fluorine ring azoles 10%, polycarboxylate 2%, lauryl sodium sulfate 3%, silicone compound 0.1%, polyvinyl alcohol 0.1%, deionized water add to 100%, the mixed 50% cyprodinil epoxiconazole suspension concentrate that gets.
Embodiment 8 35% cyprodinil epoxiconazole suspension concentrates
Cyprodinil 24%, fluorine ring azoles 11%, aliphatic amine polyoxyethylene ether 2%, silkworm excrement 3%, silicone compound 0.1%, polyethylene glycol 0.1%, ethylene glycol 3%, deionized water add to 100%, the mixed 35% cyprodinil epoxiconazole suspension concentrate that gets.
Embodiment 9 11% cyprodinil epoxiconazole suspension concentrates
Cyprodinil 10%, fluorine ring azoles 1%, lauryl sodium sulfate 4%, silicone oil 0.1%, xanthans 0.2%, ethylene glycol 5%, deionized water add to 100%, the mixed 11% cyprodinil epoxiconazole suspension concentrate that gets.
Implementation of an application example one: cyprodinil and fluorine ring azoles and be mixed to the alternaria leaf spot of apple Toxicity Determination
Reagent agent is provided by Shaanxi Pucheng County Meibang Pesticide Co., Ltd..Test strain picks up from Luochuan County suburb, Shaanxi Province, the virulence regression equation of the cyprodinil that is obtained, fluorine ring azoles and the comparison alternaria leaf spot of apple that is mixed thereof, suppress in concentration and synergy ratio (SR) as following table:
Table 1 cyprodinil, fluorine ring azoles and be mixed to the alternaria leaf spot of apple Toxicity Determination
As shown in Table 1, cyprodinil of the present invention and fluorine ring azoles are composite, to the alternaria leaf spot of apple Toxicity Determination, when cyprodinil and fluorine ring azoles proportioning are that 1: 1,2: 1,5: 1,8: 1,11: 1 synergy ratio is respectively 1.36,1.51,1.73,1.61,1.45, wherein when cyprodinil: fluorine ring azoles shows as synergistic effect when being 2: 1,5: 1,8: 1, and it is comparatively reasonable to illustrate that cyprodinil and fluorine ring azoles were mixed in the scope at 2: 1～8: 1.
Implementation of an application example two: the cyprodinil and the composite control alternaria leaf spot of apple of the fluorine ring azoles test of pesticide effectiveness
This experimental establishment is at Shaanxi Province's Luochuan County, and test medicine is researched and developed, provided by Shaanxi Pucheng County Meibang Pesticide Co., Ltd., contrast medicament 50% cyprodinil water dispersible granules (commercial), 75 grams per liter fluorine ring azoles missible oil (commercial).
In the alternaria leaf spot of apple initial stage of origination, dispenser in per 7 days once is total to dispenser 3 times, and investigation state of an illness radix before the medicine was investigated disease indexs in 7 days, 20 days behind the last medicine and calculated preventive effect, and the result is as shown in the table:
Table 2 cyprodinil, fluorine ring azoles and the control alternaria leaf spot of apple test of pesticide effectiveness that is mixed thereof
| Handle medicament | Extension rate | 7 days preventive effects (%) behind the last medicine | 20 days preventive effects (%) behind the last medicine |
| Embodiment 1 | 4000 times | ??81.37 | ??90.29 |
| Embodiment 5 | 3000 times | ??83.25 | ??92.77 |
| Embodiment 8 | 2000 times | ??86.06 | ??93.45 |
| 50% cyprodinil water dispersible granules | 1000 times | ??80.42 | ??84.05 |
| 75 grams per liter fluorine ring azoles missible oil | 600 times | ??78.33 | ??83.72 |
As shown in Table 2, can effectively prevent and treat alternaria leaf spot of apple after cyprodinil and fluorine ring azoles are composite, control efficiency all is better than contrasting medicament, and the lasting period is long, the test scope of medication in to crop safety.
Implementation of an application example three cyprodinils, fluorine ring azoles and the composite control wheat powdery mildew test of pesticide effectiveness thereof
Reagent agent: the composite product of cyprodinil fluorine ring azoles is provided by Shaanxi Pucheng County Meibang Pesticide Co., Ltd.; 50% cyprodinil water dispersible granules (commercial), 75 grams per liter fluorine ring azoles missible oil (commercial).
Test arrangement is at the Xian City, Shanxi Province Changan District, and dispenser in per 7 days once is total to dispenser 2 times, and investigation disease index before the medicine was investigated disease indexs in 7 days, 14 days behind the last medicine and calculated preventive effect.Result of the test is as follows:
Table 3 cyprodinil, fluorine ring azoles and composite control wheat powdery mildew field control effectiveness test thereof
Find out that by table 3 can effectively prevent and treat the generation of wheat powdery mildew after cyprodinil and fluorine ring azoles are composite, control efficiency is better than all contrasting medicament, in trial stretch to the target crop safety.
Implementation of an application example four: the composite sigatoka test of pesticide effectiveness of preventing and treating of cyprodinil and fluorine ring azoles
This experimental establishment is in the Guangxi province Nanning suburban district, and test medicine is researched and developed, provided by Shaanxi Pucheng County Meibang Pesticide Co., Ltd., contrast medicament 50% cyprodinil water dispersible granules (commercial), 75 grams per liter fluorine ring azoles missible oil (commercial).
In the sigatoka initial stage of origination, dispenser in per 7 days once is total to dispenser 4 times, and investigation state of an illness radix before the medicine was investigated disease indexs in 7 days, 20 days behind the last medicine and calculated preventive effect, and the result is as shown in the table:
Table 4 cyprodinil, fluorine ring azoles and be mixed and prevent and treat the sigatoka test of pesticide effectiveness
| Handle medicament | Extension rate | 7 days preventive effects (%) behind the last medicine | 20 days preventive effects (%) behind the last medicine |
| Embodiment 2 | 3000 times | ??74.29 | ??87.04 |
| Embodiment 6 | 2500 times | ??77.85 | ??89.75 |
| Embodiment 9 | 1000 times | ??80.23 | ??88.37 |
| 50% cyprodinil water dispersible granules | 1000 times | ??72.34 | ??80.77 |
| 75 grams per liter fluorine ring azoles missible oil | 600 times | ??72.57 | ??84.02 |
As shown in Table 4, can effectively prevent and treat sigatoka after cyprodinil and fluorine ring azoles are composite, control efficiency all is better than contrasting medicament, and the lasting period is long, the test scope of medication in to crop safety.
Claims (6)
1, a kind of bactericidal composition is characterized in that: composition effective active composition contains cyprodinil and fluorine ring azoles, and wherein the percentage by weight of cyprodinil and fluorine ring azoles is 10～80: 50～1.
2, the bactericidal composition that contains cyprodinil and fluorine ring azoles according to claim 1 is characterized in that the percentage by weight after cyprodinil and fluorine ring azoles are preferably is 10～70: 30～5.
3, the bactericidal composition that contains cyprodinil and fluorine ring azoles according to claim 1 is characterized in that the effective active composition weight content of cyprodinil and fluorine ring azoles is 11～80%.
4, the bactericidal composition that contains cyprodinil and fluorine ring azoles according to claim 1, the formulation that it is characterized in that composition is wetting powder, water dispersible granules, suspending agent.
5, cyprodinil and the fluorine ring azoles bactericidal composition of containing according to claim 1 is used to prevent and treat disease on fruit tree and the cereal.
6, cyprodinil and the fluorine ring azoles bactericidal composition of containing according to claim 5 is mainly used in and prevents and treats sigatoka, alternaria leaf spot of apple, wheat powdery mildew.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910023209A CN101617664A (en) | 2009-07-07 | 2009-07-07 | Sterilization composite containing cyprodinil and epoxiconazole |
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|---|---|---|---|
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102696664A (en) * | 2012-04-06 | 2012-10-03 | 陕西韦尔奇作物保护有限公司 | Sterilization composition containing mepanipyrim and triazoles |
| CN102845419A (en) * | 2012-03-29 | 2013-01-02 | 广东中迅农科股份有限公司 | Cyprodinil water dispersible granule and preparation method thereof |
| CN110367250A (en) * | 2019-08-13 | 2019-10-25 | 福建拓烯新材料科技有限公司 | A kind of microcapsule formulations composition and preparation method thereof |
-
2009
- 2009-07-07 CN CN200910023209A patent/CN101617664A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102845419A (en) * | 2012-03-29 | 2013-01-02 | 广东中迅农科股份有限公司 | Cyprodinil water dispersible granule and preparation method thereof |
| CN102845419B (en) * | 2012-03-29 | 2013-11-06 | 广东中迅农科股份有限公司 | Cyprodinil water dispersible granule and preparation method thereof |
| CN102696664A (en) * | 2012-04-06 | 2012-10-03 | 陕西韦尔奇作物保护有限公司 | Sterilization composition containing mepanipyrim and triazoles |
| CN110367250A (en) * | 2019-08-13 | 2019-10-25 | 福建拓烯新材料科技有限公司 | A kind of microcapsule formulations composition and preparation method thereof |
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Application publication date: 20100106 |