CN101790986A - Fungicide composite containing tricyclazole and hexaconazole - Google Patents
Fungicide composite containing tricyclazole and hexaconazole Download PDFInfo
- Publication number
- CN101790986A CN101790986A CN201010148112A CN201010148112A CN101790986A CN 101790986 A CN101790986 A CN 101790986A CN 201010148112 A CN201010148112 A CN 201010148112A CN 201010148112 A CN201010148112 A CN 201010148112A CN 101790986 A CN101790986 A CN 101790986A
- Authority
- CN
- China
- Prior art keywords
- tricyclazole
- azoles alcohol
- hexaconazole
- azoles
- alcohol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- DQJCHOQLCLEDLL-UHFFFAOYSA-N tricyclazole Chemical compound CC1=CC=CC2=C1N1C=NN=C1S2 DQJCHOQLCLEDLL-UHFFFAOYSA-N 0.000 title claims abstract description 150
- STMIIPIFODONDC-UHFFFAOYSA-N 2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)hexan-2-ol Chemical compound C=1C=C(Cl)C=C(Cl)C=1C(O)(CCCC)CN1C=NC=N1 STMIIPIFODONDC-UHFFFAOYSA-N 0.000 title abstract description 43
- 239000002131 composite material Substances 0.000 title abstract description 21
- 230000000855 fungicidal effect Effects 0.000 title abstract description 5
- 239000000417 fungicide Substances 0.000 title abstract 4
- 239000000839 emulsion Substances 0.000 claims abstract description 17
- 239000004530 micro-emulsion Substances 0.000 claims abstract description 17
- 239000000375 suspending agent Substances 0.000 claims abstract description 17
- 239000004562 water dispersible granule Substances 0.000 claims abstract description 17
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 104
- 150000003851 azoles Chemical class 0.000 claims description 99
- 239000000203 mixture Substances 0.000 claims description 40
- 239000000843 powder Substances 0.000 claims description 23
- 238000009736 wetting Methods 0.000 claims description 19
- 230000000844 anti-bacterial effect Effects 0.000 claims description 18
- 230000003641 microbiacidal effect Effects 0.000 claims 2
- 229940124561 microbicide Drugs 0.000 claims 2
- 239000002855 microbicide agent Substances 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 21
- 241000221785 Erysiphales Species 0.000 abstract description 15
- 239000004563 wettable powder Substances 0.000 abstract description 9
- 235000007164 Oryza sativa Nutrition 0.000 abstract description 7
- 235000009566 rice Nutrition 0.000 abstract description 7
- 239000004480 active ingredient Substances 0.000 abstract description 4
- 241000395107 Cladosporium cucumerinum Species 0.000 abstract 1
- 240000007594 Oryza sativa Species 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 49
- 230000003449 preventive effect Effects 0.000 description 22
- 238000012360 testing method Methods 0.000 description 19
- 239000008367 deionised water Substances 0.000 description 15
- 229910021641 deionized water Inorganic materials 0.000 description 15
- -1 antifreeze Substances 0.000 description 14
- FBOUIAKEJMZPQG-BLXFFLACSA-N diniconazole-M Chemical compound C1=NC=NN1/C([C@H](O)C(C)(C)C)=C/C1=CC=C(Cl)C=C1Cl FBOUIAKEJMZPQG-BLXFFLACSA-N 0.000 description 13
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 12
- 201000010099 disease Diseases 0.000 description 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 10
- 239000003921 oil Substances 0.000 description 10
- 235000019198 oils Nutrition 0.000 description 10
- 229920001296 polysiloxane Polymers 0.000 description 10
- 240000008067 Cucumis sativus Species 0.000 description 9
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 9
- 239000000575 pesticide Substances 0.000 description 9
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 8
- 210000000481 breast Anatomy 0.000 description 8
- 238000009313 farming Methods 0.000 description 8
- 230000002528 anti-freeze Effects 0.000 description 7
- 239000002270 dispersing agent Substances 0.000 description 7
- 230000002195 synergetic effect Effects 0.000 description 7
- 239000000080 wetting agent Substances 0.000 description 7
- 241000209094 Oryza Species 0.000 description 6
- 206010039509 Scab Diseases 0.000 description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 6
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 6
- 239000002518 antifoaming agent Substances 0.000 description 6
- 239000000470 constituent Substances 0.000 description 6
- JHIVVAPYMSGYDF-UHFFFAOYSA-N cyclohexanone Chemical compound O=C1CCCCC1 JHIVVAPYMSGYDF-UHFFFAOYSA-N 0.000 description 6
- 239000013530 defoamer Substances 0.000 description 6
- 229940079593 drug Drugs 0.000 description 6
- 239000003995 emulsifying agent Substances 0.000 description 6
- 235000011187 glycerol Nutrition 0.000 description 6
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 229920005646 polycarboxylate Polymers 0.000 description 6
- 239000002904 solvent Substances 0.000 description 6
- 239000002562 thickening agent Substances 0.000 description 6
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical class CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 5
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 5
- 239000004372 Polyvinyl alcohol Substances 0.000 description 5
- 240000003377 Shepherdia canadensis Species 0.000 description 5
- 235000018324 Shepherdia canadensis Nutrition 0.000 description 5
- 229920002472 Starch Polymers 0.000 description 5
- 150000004996 alkyl benzenes Chemical class 0.000 description 5
- 239000003899 bactericide agent Substances 0.000 description 5
- 239000011575 calcium Substances 0.000 description 5
- 229910052791 calcium Inorganic materials 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 5
- 239000000945 filler Substances 0.000 description 5
- 239000007789 gas Substances 0.000 description 5
- 229920002451 polyvinyl alcohol Polymers 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- 239000008107 starch Substances 0.000 description 5
- 235000019698 starch Nutrition 0.000 description 5
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 4
- 239000002202 Polyethylene glycol Substances 0.000 description 4
- 235000014443 Pyrus communis Nutrition 0.000 description 4
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 4
- 239000004283 Sodium sorbate Substances 0.000 description 4
- 241000209140 Triticum Species 0.000 description 4
- 235000021307 Triticum Nutrition 0.000 description 4
- 239000000440 bentonite Substances 0.000 description 4
- 229910000278 bentonite Inorganic materials 0.000 description 4
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 4
- 229940077388 benzenesulfonate Drugs 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 239000007859 condensation product Substances 0.000 description 4
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 4
- 238000011835 investigation Methods 0.000 description 4
- 230000002045 lasting effect Effects 0.000 description 4
- 229920001223 polyethylene glycol Polymers 0.000 description 4
- LROWVYNUWKVTCU-STWYSWDKSA-M sodium sorbate Chemical compound [Na+].C\C=C\C=C\C([O-])=O LROWVYNUWKVTCU-STWYSWDKSA-M 0.000 description 4
- 235000019250 sodium sorbate Nutrition 0.000 description 4
- 230000001018 virulence Effects 0.000 description 4
- DMAXMXPDVWTIRV-UHFFFAOYSA-N 2-(2-phenylethyl)phenol Chemical compound OC1=CC=CC=C1CCC1=CC=CC=C1 DMAXMXPDVWTIRV-UHFFFAOYSA-N 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- 239000005995 Aluminium silicate Substances 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 3
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 3
- 229920001732 Lignosulfonate Polymers 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 3
- 206010067482 No adverse event Diseases 0.000 description 3
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 description 3
- 229910019142 PO4 Inorganic materials 0.000 description 3
- 235000012211 aluminium silicate Nutrition 0.000 description 3
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 3
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 3
- 235000011130 ammonium sulphate Nutrition 0.000 description 3
- 150000007942 carboxylates Chemical class 0.000 description 3
- 239000007957 coemulsifier Substances 0.000 description 3
- 239000007884 disintegrant Substances 0.000 description 3
- NVVZQXQBYZPMLJ-UHFFFAOYSA-N formaldehyde;naphthalene-1-sulfonic acid Chemical compound O=C.C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1 NVVZQXQBYZPMLJ-UHFFFAOYSA-N 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 3
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000000149 penetrating effect Effects 0.000 description 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 3
- 239000010452 phosphate Substances 0.000 description 3
- 159000000000 sodium salts Chemical class 0.000 description 3
- 229920001285 xanthan gum Polymers 0.000 description 3
- LYCAIKOWRPUZTN-NMQOAUCRSA-N 1,2-dideuteriooxyethane Chemical compound [2H]OCCO[2H] LYCAIKOWRPUZTN-NMQOAUCRSA-N 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 239000005639 Lauric acid Substances 0.000 description 2
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 2
- 239000003905 agrochemical Substances 0.000 description 2
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 description 2
- 230000008485 antagonism Effects 0.000 description 2
- IOJUPLGTWVMSFF-UHFFFAOYSA-N benzothiazole Chemical compound C1=CC=C2SC=NC2=C1 IOJUPLGTWVMSFF-UHFFFAOYSA-N 0.000 description 2
- LLEMOWNGBBNAJR-UHFFFAOYSA-N biphenyl-2-ol Chemical compound OC1=CC=CC=C1C1=CC=CC=C1 LLEMOWNGBBNAJR-UHFFFAOYSA-N 0.000 description 2
- 239000004359 castor oil Substances 0.000 description 2
- 235000019438 castor oil Nutrition 0.000 description 2
- 210000000170 cell membrane Anatomy 0.000 description 2
- 230000002070 germicidal effect Effects 0.000 description 2
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 230000009036 growth inhibition Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 229920000609 methyl cellulose Polymers 0.000 description 2
- 239000001923 methylcellulose Substances 0.000 description 2
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 229940051841 polyoxyethylene ether Drugs 0.000 description 2
- 229920000056 polyoxyethylene ether Polymers 0.000 description 2
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 description 2
- 229920002545 silicone oil Polymers 0.000 description 2
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 2
- 235000017557 sodium bicarbonate Nutrition 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 239000003381 stabilizer Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 150000003852 triazoles Chemical class 0.000 description 2
- 239000000230 xanthan gum Substances 0.000 description 2
- 235000010493 xanthan gum Nutrition 0.000 description 2
- 229940082509 xanthan gum Drugs 0.000 description 2
- OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 description 1
- RQOCXCFLRBRBCS-UHFFFAOYSA-N (22E)-cholesta-5,7,22-trien-3beta-ol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CCC(C)C)CCC33)C)C3=CC=C21 RQOCXCFLRBRBCS-UHFFFAOYSA-N 0.000 description 1
- WKBPZYKAUNRMKP-UHFFFAOYSA-N 1-[2-(2,4-dichlorophenyl)pentyl]1,2,4-triazole Chemical compound C=1C=C(Cl)C=C(Cl)C=1C(CCC)CN1C=NC=N1 WKBPZYKAUNRMKP-UHFFFAOYSA-N 0.000 description 1
- SNTWKPAKVQFCCF-UHFFFAOYSA-N 2,3-dihydro-1h-triazole Chemical compound N1NC=CN1 SNTWKPAKVQFCCF-UHFFFAOYSA-N 0.000 description 1
- JCUDAMKYTWVICI-UHFFFAOYSA-N 4-benzyl-2,3-dimethylphenol Chemical compound C1=C(O)C(C)=C(C)C(CC=2C=CC=CC=2)=C1 JCUDAMKYTWVICI-UHFFFAOYSA-N 0.000 description 1
- PMZBHPUNQNKBOA-UHFFFAOYSA-N 5-methylbenzene-1,3-dicarboxylic acid Chemical compound CC1=CC(C(O)=O)=CC(C(O)=O)=C1 PMZBHPUNQNKBOA-UHFFFAOYSA-N 0.000 description 1
- OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000255789 Bombyx mori Species 0.000 description 1
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 1
- 229920005682 EO-PO block copolymer Polymers 0.000 description 1
- DNVPQKQSNYMLRS-NXVQYWJNSA-N Ergosterol Natural products CC(C)[C@@H](C)C=C[C@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@H]3CC[C@]12C DNVPQKQSNYMLRS-NXVQYWJNSA-N 0.000 description 1
- 239000005813 Penconazole Substances 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 229960000892 attapulgite Drugs 0.000 description 1
- 238000000498 ball milling Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004166 bioassay Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 239000006184 cosolvent Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000017858 demethylation Effects 0.000 description 1
- 238000010520 demethylation reaction Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 description 1
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
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- DNVPQKQSNYMLRS-SOWFXMKYSA-N ergosterol Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H](CC[C@]3([C@H]([C@H](C)/C=C/[C@@H](C)C(C)C)CC[C@H]33)C)C3=CC=C21 DNVPQKQSNYMLRS-SOWFXMKYSA-N 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
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- 230000010534 mechanism of action Effects 0.000 description 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- TVMXDCGIABBOFY-UHFFFAOYSA-N octane Chemical compound CCCCCCCC TVMXDCGIABBOFY-UHFFFAOYSA-N 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 229910052625 palygorskite Inorganic materials 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 229940088417 precipitated calcium carbonate Drugs 0.000 description 1
- 150000004040 pyrrolidinones Chemical class 0.000 description 1
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- 229920005989 resin Polymers 0.000 description 1
- 235000021003 saturated fats Nutrition 0.000 description 1
- PYODKQIVQIVELM-UHFFFAOYSA-M sodium;2,3-bis(2-methylpropyl)naphthalene-1-sulfonate Chemical compound [Na+].C1=CC=C2C(S([O-])(=O)=O)=C(CC(C)C)C(CC(C)C)=CC2=C1 PYODKQIVQIVELM-UHFFFAOYSA-M 0.000 description 1
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- 231100000820 toxicity test Toxicity 0.000 description 1
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Abstract
The invention relates to a fungicide composite containing tricyclazole and hexaconazole; the effective active ingredients of the fungicide composite are as follows: tricyclazole and hexaconazole, wherein the weight ratio of the tricyclazole and the hexaconazole is 5-80:40-1; auxiliaries and excipients are added in the effective active ingredients to prepare wettable powder, water dispersible granules, suspending agent, water emulsion or microemulsion, and the fungicide composite is mainly used for preventing powdery mildew, anthracnose, cladosporium cucumerinum and rice blast.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of bactericidal composition on crop pest that contains tricyclazole and own azoles alcohol.
Technical background
Tricyclazole (tricyclazole) is a triazole bactericidal agent.Molecular formula is C
9H
7N
3S, chemical name: the 5-methyl isophthalic acid, 2, the 4-triazol (3,4-b) benzothiazole.
Tricyclazole is a kind of stronger protectiveness triazole bactericidal agent of interior absorption that has, and can be absorbed, and be transported to each one of plant by root of the crop, stem, leaf rapidly.Tricyclazole antiscour power is strong, and the spray medicine is met the rain medicine that need not fill spray after one hour.Mainly be to suppress spore germination and adhere to spore to form, thereby stop germ to invade and reduce the generation of bacterium spore effectively.
Own azoles alcohol (penconazole) molecular formula: C
13H
15Cl
2N
3, chemical name: 1-[2-(2,4 dichloro benzene base)-4-propyl group-1,3-dioxolanes-2-methyl]-1-hydrogen-1,2, the 4-triazole.
Own azoles alcohol belongs to three nitrogen heterocycles bactericide, is sterol demethylation inhibitor, destroys and stop the biosynthesis of the cell membrane important composition composition ergosterol of germ, causes cell membrane not form, and is germ death.Root, stem, leaf isoreactivity tissue by crop absorb, and can upwards conduct with body fluid in the plant body soon.
No matter be tricyclazole, own azoles alcohol or other efficient germicides, long-term use separately makes disease develop immunity to drugs easily, causes the problem that dosage strengthens, preventive effect reduces, the lasting period shortens, and is unfavorable for environment sustainable development.The active ingredient of the different mechanisms of action is carried out composite, is to delay the disease method commonly used that develops immunity to drugs, and according to the effect in the production application, judge this composite be synergistic effect or antagonism.Complex role is more significantly filled a prescription, and can obviously improve preventive effect, reduces the dosage of agricultural chemicals greatly, also can enlarge fungicidal spectrum, improves germicidal efficiency.Tricyclazole is different with the own azoles alcohol mechanism of action, and composite mutually have good synergistic effect within the specific limits.And composite about tricyclazole and own azoles alcohol do not see relevant report at present at home and abroad as yet.
Summary of the invention
The objective of the invention is to propose a kind of have synergistic function, use cost is low, preventive effect the is good bactericidal composition that contains tricyclazole and own azoles alcohol.
The present invention is achieved through the following technical solutions:
A kind of bactericidal composition that contains tricyclazole and own azoles alcohol, wherein tricyclazole and own azoles alcohol weight ratio is 5～80: 40～1.
The described bactericidal composition that contains tricyclazole and own azoles alcohol, wherein the weight ratio of tricyclazole and own azoles alcohol is 10～70: 30～1.
The described bactericidal composition that contains tricyclazole and own azoles alcohol, wherein the weight ratio of tricyclazole and own azoles alcohol is 20～60: 20～1.
The described bactericidal composition that contains tricyclazole and own azoles alcohol, wherein the best ratio range of tricyclazole and own azoles alcohol is 1: 1～10: 1.
The described bactericidal composition that contains tricyclazole and own azoles alcohol, wherein the effective active component content accounts for 6～90% of gross weight; Be preferably 10～80%.
The described bactericidal composition that contains tricyclazole and own azoles alcohol is made wetting powder, water dispersible granules, suspending agent, aqueous emulsion or microemulsion.
When making wetting powder, composition comprises following constituent content: tricyclazole 5～80%, own azoles alcohol 1～40%, dispersant 5～10%, wetting agent 2～10%, filler 8～90%.
Tricyclazole, own azoles alcohol, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, promptly can be made into the own azoles alcohol of tricyclazole wetting powder product.
When making water dispersible granules, composition comprises following constituent content: tricyclazole 5～80%, own azoles alcohol 1～40%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, filler 10～90%.
Tricyclazole, own azoles alcohol, dispersant, wetting agent, disintegrant, filler etc. are obtained the particle diameter that needs through comminution by gas stream together, obtain the materials of granulating.It is interior through after granulation and the drying to expect that product are quantitatively sent the fluidized bed granulation dryer to, makes tricyclazole diniconazole water dispersible granule product.
Comprise following constituent content when composition is made suspending agent: tricyclazole 5～50%, own azoles alcohol 1～20%, dispersant 2～10%, wetting agent 2～10%, defoamer 0.1～1%, thickener 0.1～2%, emulsifier 0.5～3%, antifreeze 0.1～8%, deionized water add to 100%.
Dispersant, wetting agent, defoamer, thickener, antifreeze in the above-mentioned formulation material are mixed through high speed shear, add tricyclazole, own azoles alcohol, ball milling is 2～3 hours in ball mill, makes diameter of particle all below 5 μ m, makes tricyclazole hexaconazole suspending agent product.
Comprise following constituent content when composition is made aqueous emulsion: tricyclazole 1～50%, own azoles alcohol 1～50%, solvent 1～30%, emulsifier 1～15%, co-emulsifier 0～8%, antifreeze 0～10%, thickener 0.1～2%, defoamer 0.01～2%, deionized water are supplied surplus.
Above-mentioned formulation material is mixed, active ingredient, solvent, emulsifier, co-emulsifier are added together, make and be dissolved into even oil phase; Water, antifreeze, thickener, defoamer are mixed, become the homogeneous water.Under high-speed stirred, water is added oil phase, make tricyclazole hexaconazole aqueous emulsion product.
Comprise following constituent content when composition is made microemulsion: tricyclazole 1～50%, own azoles alcohol 1～50%, solvent 1～30%, emulsifier 3～20%, co-emulsifier 0～12%, antifreeze 0～10%, thickener 0.1～2%, defoamer 0.01～2%, stabilizing agent 0～4%, deionized water is supplied surplus.
Former medicine of tricyclazole and the former medicine of own azoles alcohol are dissolved in the homogenizer that solvent and cosolvent are housed; Mix strongly after joining emulsifier, stabilizing agent and antifreeze, water in the homogenizer that above-mentioned solution is housed and homogenize, obtain the as clear as crystal tricyclazole hexaconazole microemulsion product of outward appearance at last.
Described dispersant is selected from polycarboxylate, lignosulfonates, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy is phonetic, aliphatic amine polyoxyethylene is phonetic, in phonetic one or more of polyoxyethylene carboxylate, ester polyoxyethylene.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, silkworm excrement, the soapberry powder.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, the aluminium chloride.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, the polyethylene glycol.
Described defoamer is selected from: one or more in silicone oil, silicone compound, C10-20 saturated fat acid compounds, the C8-10 aliphatic alcohols compound.
Described thickener is selected from: one or more in xanthan gum, polyvinyl alcohol, the polyethylene glycol.
Described emulsifier is selected from: farming breast 500
#(alkyl benzene calcium sulfonate), 600
#Phosphate (phenyl phenol polyoxy ethyl ether phosphate), farming breast 400
#(benzyl dimethyl phenol polyoxy ethyl ether), farming breast 600
#(phenyl phenol polyoxy ethyl ether), Nongru-700
#(alkylphenol-formaldehyde resin polyoxy ethyl ether), farming breast 1600
#In (phenethyl phenol polyoxy ethyl polypropylene-base ether), the ethylene oxide-propylene oxide block copolymer one or more.
Described solvent is selected from one or more in toluene, dimethylbenzene, methyl alcohol, ethanol, acetone, ether, cyclohexanone, vegetable oil, dimethyl formamide, acetonitrile, polyethylene glycol, pyrrolidones, the solvent N-chain alkyl pyrrolidones;
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate.
Composition of the present invention is mainly used in powdery mildew, anthracnose, scab, the rice blast of control crop.
Beneficial effect of the present invention: (1) present composition effective active composition tricyclazole and own azoles alcohol belong to the bactericide of two kinds of different mechanisms of action, and both are mixed mutually and can produce conflict; (2) present composition has good synergistic effect within the specific limits, and preventive effect is higher than single agent, and dosage is little; (3) with an organic solvent dosage is few in the present invention, is difficult for producing poisoning, is convenient to transportation and storage; (4) present composition has special efficacy to powdery mildew, anthracnose, scab, rice blast.
Embodiment
To further instruction of the present invention, the percentage among the embodiment all is weight percentage below in conjunction with embodiment, but the present invention is not limited thereto.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.
Implementation of an application example one the implementation of Formulation Example
The own azoles alcohol of embodiment 1 80% tricyclazole wetting powder
Tricyclazole 60%, own azoles alcohol 20%, polycarboxylate 5%, lauryl sodium sulfate 3%, spaonin powder 2%, kaolin 10%, mixture carries out comminution by gas stream, makes the own azoles alcohol of 80% tricyclazole wetting powder.
The own azoles alcohol of embodiment 2 65% tricyclazoles wetting powder
Tricyclazole 35%, own azoles alcohol 30%, alkyl benzene sulfonate calcium salt 4%, wetting and penetrating agent F 4%, white carbon 8%, bentonite 19%, mixture carries out comminution by gas stream, makes the own azoles alcohol of 65% tricyclazole wetting powder.
The own azoles alcohol of embodiment 3 55% tricyclazoles wetting powder
Tricyclazole 45%, own azoles alcohol 10%, alkyl benzene sulfonate calcium salt 5%, wetting and penetrating agent F 3%, white carbon 8%, kaolin 29%, mixture carries out comminution by gas stream, makes the own azoles alcohol of 55% tricyclazole wetting powder.
The own azoles alcohol of embodiment 4 15% tricyclazoles wetting powder
Tricyclazole 10%, own azoles alcohol 5%, lignosulfonates 5%, tea are withered 5%, white carbon 35%, bentonite 40%, and mixture carries out comminution by gas stream, makes the own azoles alcohol of 15% tricyclazole wetting powder.
Embodiment 5 80% tricyclazole diniconazole water dispersible granules
Tricyclazole 70%, own azoles alcohol 10%, polycarboxylate 3%, lignosulfonates 3%, lauryl sodium sulfate 4%, ammonium sulfate 2%, starch 8%, the mixed 80% tricyclazole diniconazole water dispersible granule that gets.
Embodiment 6 70% tricyclazole diniconazole water dispersible granules
Tricyclazole 50%, own azoles alcohol 20%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 3%, polyoxyethylene carboxylate 3%, soapberry powder 4%, sodium bicarbonate 3%, starch 17%,, mixed 70% tricyclazole diniconazole water dispersible granule.
Embodiment 7 50% tricyclazole diniconazole water dispersible granules
Tricyclazole 38%, own azoles alcohol 12%, alkylphenol-polyethenoxy are phonetic 3%, polyoxyethylene carboxylate 3%, soapberry powder 4%, sodium bicarbonate 3%, starch 37%,, mixed 50% tricyclazole diniconazole water dispersible granule.
Embodiment 8 40% tricyclazole diniconazole water dispersible granules
Tricyclazole 36%, own azoles alcohol 4%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 5%, DBSA 2%, starch 20%, diatomite 33%, the mixed 40% tricyclazole diniconazole water dispersible granule that gets.
Embodiment 9 43% tricyclazole hexaconazole suspending agents
Tricyclazole 35%, own azoles alcohol 8%, alkyl benzene sulfonate calcium salt 4%, sodium lignin sulfonate 3%, DBSA 4%, silicone oil 0.1%, farming breast 600
#2%, xanthan gum 0.3%, and deionized water adds to 100%, the mixed 43% tricyclazole hexaconazole suspending agent that gets.
Embodiment 10 30% tricyclazole hexaconazole suspending agents
Tricyclazole 24%, own azoles alcohol 6%, polycarboxylate 4%, soapberry powder 5%, silicone compound 0.1%, hydroxyethylcellulose 0.1%, farming breast 1600
#2%, ethylene glycol 2%, deionized water add to 100%, the mixed 30% tricyclazole hexaconazole suspending agent that gets.
Embodiment 11 22% tricyclazole hexaconazole suspending agents
Tricyclazole 20%, own azoles alcohol 2%, polycarboxylate 4%, soapberry powder 5%, silicone compound 0.1%, hydroxyethylcellulose 0.1%, farming breast 600
#1%, ethylene glycol 2%, deionized water add to 100%, the mixed 22% tricyclazole hexaconazole suspending agent that gets.
Embodiment 12 10% tricyclazole hexaconazole suspending agents
Tricyclazole 5%, own azoles alcohol 5%, polycarboxylate 2%, neopelex 2%, silicone compound 0.1%, polyethylene glycol 0.5%, farming breast 1600
#1%, glycerine 4%, deionized water add to 100%, the mixed 10% tricyclazole hexaconazole suspending agent that gets.
Embodiment 13 48% tricyclazole hexaconazole aqueous emulsions
Tricyclazole 40%, own azoles alcohol 8%, ethanol 20%, isobutanol 5%, castor oil polyoxyethylene ether 5%, polyvinyl alcohol 1%, propane diols 5%, lauric acid 0.5%, deionized water adds to 100%, 48% mixed tricyclazole hexaconazole aqueous emulsion.
Embodiment 14 38% tricyclazole hexaconazole aqueous emulsions
Tricyclazole 20%, own azoles alcohol 18%, toluene 15%, isobutanol 5%, castor oil polyoxyethylene ether 5%, polyvinyl alcohol 1%, ammonium sulfate 4%, lauric acid 0.5%, deionized water adds to 100%, 38% mixed tricyclazole hexaconazole aqueous emulsion.
Embodiment 15 28% tricyclazole hexaconazole aqueous emulsions
Tricyclazole 18%, own azoles alcohol 10%, normal octane 15%, OP-10 phosphate 5%, butanols 5%, polyvinyl alcohol 1%, glycerine 3%, silicone defoaming agent 0.5%, deionized water adds to 100%, 28% mixed tricyclazole hexaconazole aqueous emulsion.
Embodiment 16 16% tricyclazole hexaconazole aqueous emulsions
Tricyclazole 10%, own azoles alcohol 6%, n-hexane 15%, OP-10 phosphate 5%, butanols 5%, polyvinyl alcohol 1%, glycerine 3%, silicone defoaming agent 0.5%, deionized water adds to 100%, 16% mixed tricyclazole hexaconazole aqueous emulsion.
Embodiment 17 35% tricyclazole hexaconazole microemulsions
Tricyclazole 20%, own azoles alcohol 15%, cyclohexanone 15%, agricultural newborn 600#10%, isobutanol 5%, xanthans 2%, sodium sorbate 2%, silicone defoaming agent 0.5%, deionized water adds to 100%, 35% mixed tricyclazole hexaconazole microemulsion.
Embodiment 18 25% tricyclazole hexaconazole microemulsions
Tricyclazole 20%, own azoles alcohol 5%, cyclohexanone 15%, Nongru-700 #8%, butanols 5%, hydroxyethylcellulose 2%, sodium sorbate 2%, silicone defoaming agent 0.5%, deionized water adds to 100%, 25% mixed tricyclazole hexaconazole microemulsion.
Embodiment 19 20% tricyclazole hexaconazole microemulsions
Tricyclazole 15%, own azoles alcohol 5%, glycerine 15%, phenethyl phenol polyethenoxy ether 10%, butanols 5%, methylcellulose 2%, sodium sorbate 2%, silicone defoaming agent 0.5%, deionized water adds to 100%, 20% mixed tricyclazole hexaconazole microemulsion.
Embodiment 20 11% tricyclazole hexaconazole microemulsions
Tricyclazole 10%, own azoles alcohol 1%, glycerine 15%, phenethyl phenol polyethenoxy ether 10%, butanols 5%, methylcellulose 2%, sodium sorbate 2%, silicone defoaming agent 0.5%, deionized water adds to 100%, 11% mixed tricyclazole hexaconazole microemulsion.
Implementation of an application example two: tricyclazole and own azoles alcohol are composite to the powdery mildew of cucumber Toxicity Determination
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
After the effective inhibition concentration scope of each medicament was determined in prerun, each medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament powdery mildew of cucumber.Measure colony diameter with the right-angled intersection method behind the 72h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (mg/L) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively tricyclazole and own azoles alcohol shared ratio in combination
A is a tricyclazole
B is own azoles alcohol
Result of the test is as shown in table 1:
Table 1 tricyclazole, own azoles alcohol and composite toxicity test analysis of results table thereof to powdery mildew of cucumber
As shown in Table 1, tricyclazole, own azoles alcohol are to the EC of powdery mildew of cucumber
50Be respectively 25.63mg/L and 0.37mg/L.The virulence of tricyclazole is lower than the virulence of own azoles alcohol.Tricyclazole and 1: 1,3: 1,5: 1,7: 1,10: 1 synergy ratio of own azoles alcohol proportioning are respectively 1.59,1.97,2.12,1.89,1.60, tricyclazole and own azoles alcohol is described, and both were mixed in the scope at 1: 1 to 10: 1 and all show obvious synergistic effect, synergy ratio SR maximum when tricyclazole and own azoles alcohol weight ratio is 5: 1 wherein, synergistic effect is the most obvious.
Embodiment uses three tricyclazoles and the own azoles alcohol and the composite powdery mildew of cucumber test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is at the Xian City, Shanxi Province Baqiao District, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 75% tricyclazole wettable powder (commercial), 10% own azoles alcohol missible oil (commercial).
The preceding investigation of medicine powdery mildew of cucumber disease index, in the their early stage dispenser, dispenser for the second time after 10 days, dispenser is 2 times altogether, investigates disease indexs in 7 days, 15 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 2 tricyclazole, own azoles alcohol and the composite powdery mildew of cucumber test of pesticide effectiveness of preventing and treating thereof
| Handle medicament | The preparation dosage | 7 days preventive effects (%) behind the medicine for the second time | 15 days preventive effects (%) behind the medicine for the second time |
| The own azoles alcohol of 80% tricyclazole wetting powder | 7 gram/mus | ??90.33 | ??95.12 |
| 70% tricyclazole diniconazole water dispersible granule | 8 gram/mus | ??88.25 | ??95.43 |
| 43% tricyclazole hexaconazole suspending agent | 15 gram/mus | ??92.76 | ??96.25 |
| 48% tricyclazole hexaconazole aqueous emulsion | 14 gram/mus | ??92.24 | ??96.19 |
| 35% tricyclazole hexaconazole microemulsion | 15 gram/mus | ??89.25 | ??93.38 |
| 75% tricyclazole wettable powder | 13 gram/mus | ??74.13 | ??81.21 |
| Handle medicament | The preparation dosage | 7 days preventive effects (%) behind the medicine for the second time | 15 days preventive effects (%) behind the medicine for the second time |
| 10% own azoles alcohol missible oil | 16 gram/mus | ??73.55 | ??80.84 |
As can be seen from Table 2, can effectively prevent and treat powdery mildew of cucumber after tricyclazole and own azoles alcohol are composite, control efficiency all is better than contrasting medicament, and the lasting period is long.In the test scope of medication target crop is had no adverse effects, and cucumber anthracnose is had preventive effect preferably, preventive effect reaches more than 90%.Embodiment uses four tricyclazoles and the own azoles alcohol and the composite control wheat powdery mildew test of pesticide effectiveness thereof
This experimental establishment is in the Lingbi County, Anhui Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 75% tricyclazole wettable powder (commercial), 10% own azoles alcohol missible oil (commercial).
The preceding investigation of medicine wheat powdery mildew disease index, in the their early stage dispenser, dispenser for the second time after 10 days, dispenser is 2 times altogether, investigates disease indexs in 7 days, 15 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 2 tricyclazole, own azoles alcohol and the composite control wheat powdery mildew test of pesticide effectiveness thereof
| Handle medicament | The preparation dosage | 7 days preventive effects (%) behind the medicine for the second time | 15 days preventive effects (%) behind the medicine for the second time |
| The own azoles alcohol of 65% tricyclazole wetting powder | 10 gram/mus | ??88.68 | ??94.14 |
| 50% tricyclazole diniconazole water dispersible granule | 12 gram/mus | ??89.58 | ??95.55 |
| 30% tricyclazole hexaconazole suspending agent | 18 gram/mus | ??87.47 | ??93.51 |
| 38% tricyclazole hexaconazole aqueous emulsion | 21 gram/mus | ??88.94 | ??93.58 |
| 25% tricyclazole hexaconazole microemulsion | 15 gram/mus | ??88.27 | ??93.94 |
| 75% tricyclazole wettable powder | 13 gram/mus | ??74.39 | ??80.65 |
| 10% own azoles alcohol missible oil | 16 gram/mus | ??75.27 | ??81.42 |
As can be seen from Table 2, can effectively prevent and treat wheat powdery mildew after tricyclazole and own azoles alcohol are composite, control efficiency all is better than contrasting medicament, and the lasting period is long.In the test scope of medication, the target crop is had no adverse effects.
Implementation of an application example five tricyclazoles and the own azoles alcohol and the composite pear scab test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is in area just outside a city gate town, Pucheng County, Shaanxi Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 75% tricyclazole wettable powder (commercial), 10% own azoles alcohol missible oil (commercial).
In the dispenser of pear scab their early stage, dispenser in per 7 days once is total to dispenser 3 times, and investigation disease index before the dispenser was investigated disease index respectively in 7 days, 15 days after the 3rd dispenser, and calculated preventive effect, and result of the test is as follows:
Table 4 tricyclazole and the own azoles alcohol and the composite pear scab test of pesticide effectiveness of preventing and treating thereof
| Handle medicament | Extension rate | 7 days preventive effects (%) behind the medicine for the second time | 15 days preventive effects (%) behind the medicine for the second time |
| The own azoles alcohol of 55% tricyclazole wetting powder | 5500 times | ??89.42 | ??94.82 |
| 40% tricyclazole diniconazole water dispersible granule | 2800 times | ??90.26 | ??95.57 |
| 10% tricyclazole hexaconazole suspending agent | 2000 times | ??90.67 | ??93.83 |
| 28% tricyclazole hexaconazole aqueous emulsion | 2500 times | ??88.94 | ??93.57 |
| 20% tricyclazole hexaconazole microemulsion | 2500 times | ??88.48 | ??93.76 |
| 75% tricyclazole wettable powder | 3000 times | ??71.34 | ??78.63 |
| 10% own azoles alcohol missible oil | 2500 times | ??73.75 | ??79.06 |
As can be seen from Table 4, tricyclazole, own azoles alcohol energy effectively preventing pear scab, control efficiency all is better than contrasting medicament, and dosage is little, in the test scope of medication target crop is not had harm.
Embodiment uses six tricyclazoles and the own azoles alcohol and the composite control rice blast test of pesticide effectiveness thereof
This experimental establishment is in Hanzhong City suburb, Shaanxi Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 75% tricyclazole wettable powder (commercial), 10% own azoles alcohol missible oil (commercial).
The preceding investigation of medicine rice blast disease index, in the their early stage dispenser, dispenser for the second time after 10 days, dispenser is 2 times altogether, investigates disease indexs in 7 days, 15 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 5 tricyclazole, own azoles alcohol and the composite control rice blast test of pesticide effectiveness thereof
| Handle medicament | The preparation dosage | 7 days preventive effects (%) behind the medicine for the second time | 15 days preventive effects (%) behind the medicine for the second time |
| The own azoles alcohol of 15% tricyclazole wetting powder | 30 gram/mus | ??90.93 | ??95.65 |
| 80% tricyclazole diniconazole water dispersible granule | 6 gram/mus | ??89.57 | ??94.35 |
| 22% tricyclazole hexaconazole suspending agent | 28 gram/mus | ??91.57 | ??96.61 |
| 16% tricyclazole hexaconazole aqueous emulsion | 30 gram/mus | ??89.64 | ??95.57 |
| 11% tricyclazole hexaconazole microemulsion | 35 gram/mus | ??91.24 | ??95.83 |
| Handle medicament | The preparation dosage | 7 days preventive effects (%) behind the medicine for the second time | 15 days preventive effects (%) behind the medicine for the second time |
| 75% tricyclazole wettable powder | 15 gram/mus | ??73.38 | ??79.53 |
| 10% own azoles alcohol missible oil | 18 gram/mus | ??74.32 | ??81.54 |
As can be seen from Table 5, can effectively prevent and treat rice blast after tricyclazole and own azoles alcohol are composite, control efficiency all is better than contrasting medicament, and the lasting period is long.In the test scope of medication, the target crop is had no adverse effects.
Claims (6)
1. bactericidal composition that contains tricyclazole and own azoles alcohol, the weight ratio that it is characterized in that microbicide compositions effective active composition tricyclazole and own azoles alcohol is 5～80: 40～1.
2. the bactericidal composition that contains tricyclazole and own azoles alcohol according to claim 1 is characterized in that: wherein the weight ratio of tricyclazole and own azoles alcohol is 10～70: 30～1.
3. the bactericidal composition that contains tricyclazole and own azoles alcohol according to claim 2 is characterized in that: wherein the weight ratio of tricyclazole and own azoles alcohol is 20～60: 20～1.
4. the bactericidal composition that contains tricyclazole and own azoles alcohol according to claim 1, it is characterized in that: wherein the effective active component content accounts for 6～90% of gross weight.
5. the bactericidal composition that contains tricyclazole and own azoles alcohol according to claim 4, it is characterized in that: wherein the effective active component content accounts for 10～80% of gross weight.
6. the bactericidal composition that contains tricyclazole and own azoles alcohol according to claim 1, it is characterized in that: microbicide compositions is made wetting powder, water dispersible granules, suspending agent, aqueous emulsion or microemulsion.
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| CN102027987A (en) * | 2010-12-30 | 2011-04-27 | 陕西美邦农药有限公司 | Metconazole-containing pesticide composition |
| CN102150664A (en) * | 2011-02-25 | 2011-08-17 | 陕西美邦农药有限公司 | Penconazole-containing pesticide composition |
| CN102349522A (en) * | 2011-09-15 | 2012-02-15 | 江阴苏利化学有限公司 | Synergy sterilizing composition containing tetraconazole and tricyclazole |
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| CN102349522A (en) * | 2011-09-15 | 2012-02-15 | 江阴苏利化学有限公司 | Synergy sterilizing composition containing tetraconazole and tricyclazole |
| CN102349522B (en) * | 2011-09-15 | 2013-06-05 | 江阴苏利化学有限公司 | Synergy sterilizing composition containing tetraconazole and tricyclazole |
| CN102960355A (en) * | 2012-12-11 | 2013-03-13 | 江苏龙灯化学有限公司 | Improved water dispersive granule |
| CN104396972A (en) * | 2014-10-25 | 2015-03-11 | 北京燕化永乐生物科技股份有限公司 | Compound bactericide |
| CN107973807A (en) * | 2018-01-19 | 2018-05-01 | 唐山学院 | A kind of triazol benzothiazole derivant and its preparation method and application |
| CN107973807B (en) * | 2018-01-19 | 2020-07-10 | 唐山学院 | Triazolobenzothiazole derivative and preparation method and application thereof |
| WO2019215593A1 (en) * | 2018-05-07 | 2019-11-14 | Indofil Industries Limited | Synergistic fungicidal composition and a process for preparation thereof |
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| CN101790986B (en) | 2013-11-27 |
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Address after: 715500 Shaanxi Pucheng County agricultural base industrial park Patentee after: Shaanxi Meibang pesticide Co.,Ltd. Address before: 710075, Jinqiao International C block, 15, Xi'an hi tech Zone, Shaanxi, China Patentee before: Shaanxi Meibang pesticide Co.,Ltd. |
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Application publication date: 20100804 Assignee: SHAANXI SUNGER ROAD BIO-SCIENCE Co.,Ltd. Assignor: SHAANXI MEIBANG PHARMACEUTICAL GROUP Co.,Ltd. Contract record no.: X2021980003933 Denomination of invention: A bactericidal composition containing Tricyclazole and hexaconazole Granted publication date: 20131127 License type: Common License Record date: 20210525 |
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