CN101612288B - Traditional Chinese medicine for treating diabetic retinopathy - Google Patents
Traditional Chinese medicine for treating diabetic retinopathy Download PDFInfo
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- CN101612288B CN101612288B CN2009101441388A CN200910144138A CN101612288B CN 101612288 B CN101612288 B CN 101612288B CN 2009101441388 A CN2009101441388 A CN 2009101441388A CN 200910144138 A CN200910144138 A CN 200910144138A CN 101612288 B CN101612288 B CN 101612288B
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Abstract
The invention relates to a traditional Chinese medicine for treating diabetic retinopathy, which is characterized by comprising the following raw material medicines: rehmanniae vaporata, yam, salivia chinensis, tuckahoe, stir-fried wild rue, chrysanthemum, Chinese dodder, medlar, calcined sea-ear shell, rhizoma alismatis, angelica, flasem milkvetch seed and pale butterflybush flower. The traditional Chinese medicine can obtain the treating targets of good effect, quick acting and high cure rate to the therapy of the diabetes diabetic retinopathy.
Description
Technical field
The present invention relates to a kind of Chinese medicine, the Chinese medicine that particularly a kind of treatment of diabetic retinopathy becomes.
Background technology
Diabetic renal papillary necrosis is a kind of common clinical, how to remain high, to consume the diabetic microvascular complication of hindering essence and blood and causing by the long-term blood glucose of diabetes.Getting rid of under other factor situations as can be known through the inspection optical fundus, visual deterioration, blurring of vision as onset diabetes poor blood glucose control in two years, just is easy to occur retinopathy.The lighter early controls and can cure, and weight person loses to control and can make eyes blind, and the course of disease is touching.The present domestic specific treatment method of also not having is that general Western medicine is kept or laser therapy, and often the optical fundus breakage forms the blind person.
Summary of the invention
The present invention is for avoiding above-mentioned existing in prior technology weak point, a kind of Chinese medicine of treatment of diabetic retinopathy change being provided, in the hope of effective to diabetic renal papillary necrosis treatment acquisition, and instant effect, the therapeutic goal that cure rate is high.
Technical solution problem of the present invention adopts following technical scheme:
The Chinese medicine that treatment of diabetic retinopathy of the present invention becomes, its crude drug constitutes:
Radix Rehmanniae Preparata 15-20g, Rhizoma Dioscoreae 10-20g, Cortex Moutan 3-5g, Poria 10-15g, stir-baked FRUCTUS TRIBULI 5-10g,
Flos Chrysanthemi 3-8g, Semen Cuscutae 5-10g, Fructus Lycii 5-10g, Concha Haliotidis (calcined) 5-15g, Rhizoma Alismatis 3-5g,
Radix Angelicae Sinensis 5-10, Semen Astragali Complanati 5-10g, Flos Buddlejae 5-10g.
The crude drug of the Chinese medicine that treatment of diabetic retinopathy of the present invention becomes constitute also can be further into:
Radix Rehmanniae Preparata 15g, Rhizoma Dioscoreae 10g, Cortex Moutan 5g, Poria 10g, stir-baked FRUCTUS TRIBULI 7g, Flos Chrysanthemi 8g,
Semen Cuscutae 10g, Fructus Lycii 10g, Concha Haliotidis (calcined) 10g, Rhizoma Alismatis 3g, Radix Angelicae Sinensis 5g, Semen Astragali Complanati 10g,
Flos Buddlejae 10g.
Process for preparing medicine of the present invention is:
1, all medicinal pulverizers are pulverized, and break into 80 order medicated powder.
2, medicated powder is packed into before the zero capsule with disinfection by ultraviolet light once;
3, the medicated powder of sterilizing is left in sterile workshop, make every zero capsule that contains 0.4g medicated powder, in the bottle of packing into, hermetic container is preserved the standby finished product that is.
In the compatibility of drugs of the present invention:
Radix Rehmanniae Preparata: contain rehmanin, the catalpol several amino acids.Pharmacological action: hemostasis, heart tonifying, blood sugar lowering, treatment diabetes.Sweet in flavor and warm in property, go into the Liver and kidney warp.Cure mainly: deficiency of kidney-YIN, deficiency of liver-blood.
Rhizoma Dioscoreae: contain Saponin, phlegmatic temperament, arginine, allantoin, amylase etc.Pharmacological action: the QI invigorating spleen reinforcing, dysentery relieving removes expectorant.Nature and flavor are sweet flat, go into spleen lung kidney channel.Function: spleen benefiting and stimulating the appetite, QI invigorating arresting seminal emission.Cure mainly: a little less than the stomach of suffering from a deficiency of the kidney, anorexia is just counted, and quenches one's thirst a little less than the lung.
Cortex Moutan: contain paeonol, benzoic acid plant sterol, tannin etc.The nature and flavor toil is cold, goes into the conscience kidney channel.Function: clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.Cure mainly: stagnation of liver-QI hyperactivity of fire, acute appendicitis, hypertension, low grade fever hectic fever, hemorrhage etc.Pharmacological action: antibiotic blood pressure lowering.
Poria: contain pachymose, pachymic acid, protein, fat, lecithin.Pharmacological action: diuresis is nourished calm.Nature and flavor are sweet flat, go into heart spleen lung kidney stomach warp.Function: diuresis, strengthening the spleen mind calming.Cure mainly: edema, phlegm retention, vomiting, diarrhoea.Cure mainly: edema, phlegm retention.
Stir-baked FRUCTUS TRIBULI: contain volatile oil, Fructus Tribuli glycoside, alkaloid.Pharmacological action: soothing the liver relieving dizziness, high fever, infantile convulsions, epilepsy, etc., clots absorbing go to stagnate, and resolving depression makes eye bright, and is antipruritic.The bitter temperature of nature and flavor is gone into the liver lung meridian.Function: soothing the liver making eye bright.Cure mainly: headache, conjunctival congestion is shed tears.
Flos Chrysanthemi: contain adenine, stachydrine, choline, volatile oil.Pharmacological action: the heat radiation detoxifcation makes eye bright.Function: heat extraction liver heat removing and eyesight improving.Cure mainly: wind heat dizziness, headache conjunctival congestion.
Semen Cuscutae: contain materials such as Semen Cuscutae fat glycoside, amylase and vitamin A.Pharmacological action: the kidney invigorating, benefit be smart, make eye bright the solid tire of antidiarrheal.Sweet in flavor and warm in property, go into spleen Liver and kidney warp.Function: tonifying liver strengthening the spleen.Cure mainly: soreness of waist spermatorrhea, poor vision, incontinence of urine is used for the treatment of and looks the illiteracy dim eyesight due to the deficiency of the liver and kindey.
Fructus Lycii: contain betanin, vitamin A, B, C, D, calcium, ferrum, phosphorus etc.Pharmacological action: invigorating the liver and kidney benefiting essence-blood.Nature and flavor are sweet flat, go into liver lung kidney channel.Function: invigorating the liver and kidney, lung moistening makes eye bright.Cure mainly: the hepatic and renal YIN deficiency, waist soreness, the vertigo is quenched one's thirst.
Concha Haliotidis (calcined): contain calcium carbonate.Pharmacological action: let out liver-heat clearly.Cure mainly: dizzy infantile convulsion, conjunctival congestion is used for new and old nebula film.
Rhizoma Alismatis: contain furfural, volatile oil, ethanol extract, alkaloid, plant sterol and asparagine.Pharmacological action: diuresis blood sugar lowering, cholesterol reducing.Sweet in flavor and cold in property, go into the kidney urinary bladder channel.Function: diuretic expels the heat-evil.Cure mainly: dysuria, hematuria, phlegm retention, edema.
Radix Angelicae Sinensis: contain volatile oil, sucrose, vitamin B12.Pharmacological action: the promoting blood flow to regulate menstruation of enriching blood, intestine moistening.Nature and flavor toil temperature is gone into the conscience spleen channel.Function: the promoting blood flow to regulate menstruation of enriching blood.Cure mainly: menoxenia, blood deficiency and blood stasis amenorrhea, rheumatic arthralgia, constipation etc.
Semen Astragali Complanati: contain retinoid material, fat, tannin.Pharmacological action: the controlling nocturnal emission with astringent drugs kidney tonifying makes eye bright.Sweet in flavor and warm in property, go into the Liver and kidney warp.Function: invigorating the liver and kidney makes eye bright.Cure mainly: deficiency of the liver and kindey, dizziness and blurred vision, seminal emission premature ejaculation, poor vision, frequent micturition, leukorrhagia etc.
Flos Buddlejae: contain linarin.Pharmacological action: remove wind and make eye bright.Sweet in flavor and cold in property, go into Liver Channel.Function: improving acuity of vision and removing nebula.Cure mainly: the conjunctival congestion cataracta.Be used for the ophthalmology blurred vision, blurring of vision, photophobia is shed tears etc.
Chinese medicine thinks that diabetic renal papillary necrosis and Liver and kidney have substantial connection, belongs to traditional Chinese medical science pupil disease and becomes, and pupil god is at dirty genus kidney, the kidney essense abundance, and the pupil gods are clear, illuminating mirror and looking, and are open infinite.
Compared with the prior art, beneficial effect of the present invention is embodied in:
1, medication of the present invention is reasonable, the compatibility science.In the compatibility of the present invention, Radix Rehmanniae Preparata nourishing kidney replenishing essence, Semen Astragali Complanati, Semen Cuscutae the kidney invigorating and essence nourishing, three medicines are monarch drug; Fructus Lycii, Rhizoma Dioscoreae nourishing the liver and kidney, strengthening the spleen the moon and controlling nocturnal emission with astringent drugs is a ministerial drug; It is turbid in case Radix Rehmanniae Preparata is greasy that Rhizoma Alismatis lets out kidney; The light wet strengthening the spleen of Rhizoma Dioscoreae that helps of spleen that oozes of Poria is assistant; Chinese Angelica blood replonishing is enriched blood and easing the affected liver, liver-QI being connected with eyes, and liver opening at eye, visual acuity is obtained from the sufficient blood supply of the eyes, adding Flos Chrysanthemi, Concha Haliotidis (calcined), stir-baked FRUCTUS TRIBULI, Flos Buddlejae again is messenger drug to make eye bright.The all medical instruments of the present invention have three cloudy Bing to mend, and let out clearly and the characteristics of usefulness, but mend and do not stay heresy, fall to let out and just do not hinder, and invigorating middle warmer has rushes down, and residence is let out in benefit, complements each other, and plays the kidney invigorating and essence nourishing altogether, the merit of nourishing the liver to improve visual acuity.
2, the present invention routine patient surplus the clinical treatment 500, effective percentage reaches 100%, and cure rate reaches 93%.
3, technology of the present invention is simple, and treatment is convenient, and instant effect has no side effect, and does not recur after healing, and expense cost is low.
Consumption of the present invention is oral: each 5-6 grain (containing crude drug 2-2.4g altogether), three times on the one, taking medicine after meal boiled water takes.
The specific embodiment
In concrete the enforcement, the Chinese medicine that treatment of diabetic retinopathy becomes can be filled a prescription by following tabulation 1:
Table 1
Present embodiment carries out compatibility of drugs by the 5th group of value in the table 1:
Radix Rehmanniae Preparata 15g, Rhizoma Dioscoreae 10g, Cortex Moutan 5g, Poria 10g, stir-baked FRUCTUS TRIBULI 7g, Flos Chrysanthemi 8g,
Semen Cuscutae 10g, Fructus Lycii 10g, Concha Haliotidis (calcined) 10g, Rhizoma Alismatis 3g, Radix Angelicae Sinensis 5g, Semen Astragali Complanati 10g,
Flos Buddlejae 10g..
The preparation process of medicine is:
1, all medicinal pulverizers are pulverized, and break into 80 order medicated powder.
2, medicated powder is packed into before the zero capsule with disinfection by ultraviolet light once;
3, the medicated powder of sterilizing is left in sterile workshop, make every zero capsule that contains 0.4g medicated powder, in the bottle of packing into, hermetic container is preserved the standby finished product that is.
The present invention is through clinical practice, and it is as follows to enumerate typical case history:
Guo, man, 57 years old, businessman.People from Henan.Suffered from diabetes in 1988, the clothes western medicine, general blood glucose is between 7-10mmol/l, and I live irregular, and am hungry full variable.Two eye visions descend after 4 years, and blurred vision has microangioma and little petechia through ophthalmofundoscopy discovery 1, retina.2, retina has that HUANGBAI(sic) is rigid oozes out.3, retina has soft oozing out.Be diagnosed as the simple property of diabetic retinopathy.Once obeying persantin, vitamin C effect does not show.Change clothes Chinese medicine of the present invention from May, 1993, each 5, day three boiled water of clothes take.Vision takes a turn for the better after January, and the binocular vision rises to 0.3 by original 0.2, and continue and take medicine three months, vision restoration to 0.5 on inspection, vision is all normal under the situation of glycemic control.
The Shen, woman, 64 years old, cadre, Shanghai people.Main suit in April, 1998 during prescription on individual diagnosis, unexpected symptom more than three is obvious, fasting glucose 13.6mmol/l on inspection, and post-prandial glycemia 28.6mmol/l, glucose in urine ++ ++, with each 10 of clothes diabetes pill, day clothes three times, diamicron three times on the one, an a slice.Check fasting glucose 8.6mmol/l behind the fortnight, glucose in urine+.Continue clothes two weeks of medicine-feeding check blood glucose 5.9mmol/l, glucose in urine one.After just keep treatment, each a slice day of diamicron clothes once.In June, 07 is because of accidentally suffering from heavy cold, blood sugar increasing, and fasting glucose 9.8mmol/l, glucose in urine ++, two eye visions descend, blurred vision, and headache, dizziness, two optical fundus microscopical examination showed: 1, retina has microangioma and little petechia; 2, retina has that HUANGBAI(sic) is rigid oozes out; 3, retina has soft oozing out.Get rid of other factors, be diagnosed as the simple property of diabetes retinopathy, under the situation of blood sugar control, oral soft gelatin capsule of the present invention, each 5 day obeys three times, treat after three months, reach 0.5 through having an eyesight test, retina microangioma disappears, no petechia, the retina HUANGBAI(sic) is rigid, soft oozes out absorption, and all recover normal.
Zhao, man, 59 years old, cadre, Inner Mongol ancients.In JIUYUE, 2008 is gone to a doctor.The main suit: health is become thin weakly gradually before 2 years, and defecation is normal substantially, appetite still can, easy catching a cold is difficult to recover, in November, 06 unexpected slurred speech, the extremity limitation of activity, two eye vision decline blurred vision are lived hospital and are looked into and control.CT shows cerebral thrombosis, fasting glucose 18.6mmol/l, and glucose in urine ++ ++, examination of ocular fundus finds that venectasia is arranged, microangioma oozes out, and is hemorrhage, phenomenons such as edema.Be diagnosed as the latent diabetes complicated simple property retinopathy of type.Through the thromboembolism preventing glucose-lowering treatment, health can be taken care of oneself, and blood glucose is normal substantially, and only vision continues to descend, except that blood sugar control, oral soft gelatin capsule of the present invention, each 5, day clothes three times serve on three months, and vision returns to 0.3 by original 0.2, imitate more not just, obey half a year, vision restoration to 0.5 again, the examination of ocular fundus venectasia disappears, and microangioma disappears, and nothing is oozed out, no hemorrhage, phenomenons such as no edema, and fully recover.
By following diagnostic criteria, it is as shown in table 2 through the statistics of clinical practice to provide the present invention.
Primary disease is divided into two kinds of simple type and appreciation types.
Simple type divided for three phases:
The I phase: retina have microaneurysm or and with little petechia is arranged.
The II phase: retina has and rigidly oozes out or and the petechia arranged.
The III phase: retina has and softly oozes out or and the petechia arranged.
Proliferous type divided for three phases:
The IV phase: retina has new vessels or vitreous hemorrhage.
The V phase: retina has new vessels and fiber propagation.
The VI phase: retina has the concurrent detachment of retina of new vessels.
Effective standard: the retina point-like is hemorrhage and ooze out the absorption that has in various degree, and blood capillary no longer increases.
Criterion of cure: vision restoration is normal 0.5, hemorrhage machine absorption, and microangioma disappears not have and oozes out.
Table 2
Claims (2)
1. the Chinese medicine of treatment of diabetic retinopathy change is characterized in that crude drug constitutes: Radix Rehmanniae Preparata 15-20g, Rhizoma Dioscoreae 10-20g, Cortex Moutan 3-5g, Poria 10-15g, stir-baked FRUCTUS TRIBULI 5-10g, Flos Chrysanthemi 3-8g, Semen Cuscutae 5-10g, Fructus Lycii 5-10g, Concha Haliotidis (calcined) 5-15g, Rhizoma Alismatis 3-5g, Radix Angelicae Sinensis 5-10g, Semen Astragali Complanati 5-10g, Flos Buddlejae 5-10g.
2. the Chinese medicine that treatment of diabetic retinopathy according to claim 1 becomes is characterized in that crude drug constitutes: Radix Rehmanniae Preparata 15g, Rhizoma Dioscoreae 10g, Cortex Moutan 5g, Poria 10g, stir-baked FRUCTUS TRIBULI 7g, Flos Chrysanthemi 8g, Semen Cuscutae 10g, Fructus Lycii 10g, Concha Haliotidis (calcined) 10g, Rhizoma Alismatis 3g, Radix Angelicae Sinensis 5g, Semen Astragali Complanati 10g, Flos Buddlejae 10g.
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| CN102309607B (en) * | 2011-09-14 | 2013-05-08 | 汝州市济仁糖尿病医院 | Chinese medicine decoction for treating diabetic retinopathy and preparation method thereof |
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Non-Patent Citations (3)
| Title |
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| 中华人民共和国卫生部药典委员会.明目地黄丸.《中药成方制剂第九册》.1994,94. * |
| 汝亚琴等.中医药治疗糖尿病性视网膜病变概况.《中国中医药信息杂志》.2003,第10卷(第6期),87-89. * |
| 胡艳丽.糖尿病视网膜病变的中医治疗进展.《河北中医》.2006,第28卷(第6期),478-480. * |
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