CN101611313A - 质谱法生物标记测定 - Google Patents

质谱法生物标记测定 Download PDF

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Publication number
CN101611313A
CN101611313A CNA2007800219002A CN200780021900A CN101611313A CN 101611313 A CN101611313 A CN 101611313A CN A2007800219002 A CNA2007800219002 A CN A2007800219002A CN 200780021900 A CN200780021900 A CN 200780021900A CN 101611313 A CN101611313 A CN 101611313A
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CN
China
Prior art keywords
biomarker
signal
sample
quality
msba
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Pending
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CNA2007800219002A
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English (en)
Chinese (zh)
Inventor
西村俊秀
荻原淳
川村猛
T·卡瓦卡米
京野完
金泽光洋
F·尼贝里
G·马科-瓦加
安养寺久荣
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AstraZeneca UK Ltd
Medical Proteoscope Co Ltd
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AstraZeneca UK Ltd
Medical Proteoscope Co Ltd
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Application filed by AstraZeneca UK Ltd, Medical Proteoscope Co Ltd filed Critical AstraZeneca UK Ltd
Publication of CN101611313A publication Critical patent/CN101611313A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/74—Optical detectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
CNA2007800219002A 2006-06-13 2007-06-13 质谱法生物标记测定 Pending CN101611313A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0611669.3A GB0611669D0 (en) 2006-06-13 2006-06-13 Mass spectrometry biomarker assay
GB0611669.3 2006-06-13

Publications (1)

Publication Number Publication Date
CN101611313A true CN101611313A (zh) 2009-12-23

Family

ID=36745797

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2007800219002A Pending CN101611313A (zh) 2006-06-13 2007-06-13 质谱法生物标记测定

Country Status (10)

Country Link
EP (1) EP2035829A2 (ko)
JP (1) JP2009540319A (ko)
KR (1) KR20090068199A (ko)
CN (1) CN101611313A (ko)
AU (1) AU2007258970A1 (ko)
BR (1) BRPI0711967A2 (ko)
CA (1) CA2651934A1 (ko)
GB (1) GB0611669D0 (ko)
MX (1) MX2008015158A (ko)
WO (1) WO2007144606A2 (ko)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102201039A (zh) * 2010-08-19 2011-09-28 上海聚类生物科技有限公司 一种分析ltq数据的方法
CN107683476A (zh) * 2015-05-29 2018-02-09 英国质谱公司 样品质谱分析
CN108427002A (zh) * 2017-02-13 2018-08-21 萨默费尼根有限公司 生成用于靶向质谱分析的包含列表的方法
CN109416360A (zh) * 2016-03-31 2019-03-01 迪森德克斯公司 生物标志物数据库的生成和用途
CN109477840A (zh) * 2016-05-24 2019-03-15 因欧沃私人有限责任公司 用于在卵内非破坏性地确定家禽性别的方法和系统
CN109863239A (zh) * 2016-08-19 2019-06-07 莫纳什大学 用于病原体的鉴定和定量的光谱学系统和方法
CN111316106A (zh) * 2017-09-05 2020-06-19 迪森德克斯公司 自动化样品工作流程门控和数据分析
CN111479464A (zh) * 2017-12-22 2020-07-31 阿西姆普托特有限公司 与用于生物样品的冷却条件相关的方法和系统
CN111672658A (zh) * 2020-06-08 2020-09-18 深圳市康泓威科技有限公司 电子雾化设备最佳雾化温度的检测与控制方法及其电子雾化设备
CN112424825A (zh) * 2018-05-15 2021-02-26 文塔纳医疗系统公司 染色聚集体中信号的定量
CN114965728A (zh) * 2021-02-18 2022-08-30 塞莫费雪科学（不来梅）有限公司 用数据非依赖性采集质谱分析生物分子样品的方法和设备

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9793100B2 (en) * 2008-07-23 2017-10-17 Samir Al Moussalami Portable plasma based diagnostic apparatus and diagnostic method
GB0906698D0 (en) 2009-04-17 2009-06-03 Queen Mary & Westfield College Method for quantifying modified peptides
KR101144237B1 (ko) * 2009-12-29 2012-05-11 한국기초과학지원연구원 고분해능 질량분석법과 약리활성검사를 이용한 천연물의 약리 활성물질 발굴 방법
GB201006360D0 (en) * 2010-04-16 2010-06-02 Immatics Biotechnologies Gmbh Method for differentially quantifying naturally processed HLA-restricted peptides for cancer, autoimmune and infectious diseases immunotherapy development
US9141756B1 (en) 2010-07-20 2015-09-22 University Of Southern California Multi-scale complex systems transdisciplinary analysis of response to therapy
GB201204278D0 (en) 2012-03-09 2012-04-25 Queen Mary & Westfield College Method
FR3016461B1 (fr) * 2014-01-10 2017-06-23 Imabiotech Procede de traitement de donnees d'imagerie moleculaire et serveur de donnees correspondant
DE102014000646B4 (de) 2014-01-17 2023-05-11 Bruker Daltonics GmbH & Co. KG Massenspektrometrische Resistenzbestimmung durch Metabolismus-Messung
WO2017142025A1 (ja) * 2016-02-19 2017-08-24 国立大学法人宮崎大学 腺癌の検出方法
SG11201908865WA (en) * 2017-06-29 2019-10-30 Quanticision Diagnostics Inc Apparatus and method for absolute quantification of biomarkers for solid tumor diagnosis
WO2019046814A1 (en) 2017-09-01 2019-03-07 Venn Biosciences Corporation IDENTIFICATION AND USE OF GLYCOPEPTIDES AS BIOMARKERS FOR THE DIAGNOSIS AND MONITORING OF TREATMENT
CN113383236A (zh) * 2018-11-23 2021-09-10 新加坡科技研究局 多属性鉴定未知生物样品的方法
KR102632163B1 (ko) 2022-04-13 2024-02-01 오보젠 주식회사 가금류 알(卵)의 암수 검사 및 선별장치 그리고 이를 이용한 선별방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8014952B2 (en) * 2002-12-18 2011-09-06 Queen Elizabeth Hospital Serum biomarkers in lung cancer
DE10324149A1 (de) * 2003-05-26 2004-12-16 Imat-Uve Gmbh Verfahren und Vorrichtung zur GC/MS- oder LC/MS-Screeninganalyse
US20090204334A1 (en) * 2004-03-30 2009-08-13 Eastern Virginia Medical School Lung cancer biomarkers
DE112005001166B4 (de) * 2004-05-20 2014-10-09 Waters Technologies Corp. (N.D.Ges.D. Staates Delaware) Verfahren und Vorrichtung zum Identifizieren von Proteinen in Gemischen

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102201039A (zh) * 2010-08-19 2011-09-28 上海聚类生物科技有限公司 一种分析ltq数据的方法
CN107683476A (zh) * 2015-05-29 2018-02-09 英国质谱公司 样品质谱分析
CN109416360A (zh) * 2016-03-31 2019-03-01 迪森德克斯公司 生物标志物数据库的生成和用途
CN109477840B (zh) * 2016-05-24 2022-12-23 因欧沃控股私人有限责任公司 用于在卵内非破坏性地确定家禽性别的方法和系统
CN109477840A (zh) * 2016-05-24 2019-03-15 因欧沃私人有限责任公司 用于在卵内非破坏性地确定家禽性别的方法和系统
CN109863239A (zh) * 2016-08-19 2019-06-07 莫纳什大学 用于病原体的鉴定和定量的光谱学系统和方法
CN108427002B (zh) * 2017-02-13 2021-01-12 萨默费尼根有限公司 生成用于靶向质谱分析的包含列表的方法
CN108427002A (zh) * 2017-02-13 2018-08-21 萨默费尼根有限公司 生成用于靶向质谱分析的包含列表的方法
CN111316106A (zh) * 2017-09-05 2020-06-19 迪森德克斯公司 自动化样品工作流程门控和数据分析
CN111479464A (zh) * 2017-12-22 2020-07-31 阿西姆普托特有限公司 与用于生物样品的冷却条件相关的方法和系统
CN112424825A (zh) * 2018-05-15 2021-02-26 文塔纳医疗系统公司 染色聚集体中信号的定量
CN111672658A (zh) * 2020-06-08 2020-09-18 深圳市康泓威科技有限公司 电子雾化设备最佳雾化温度的检测与控制方法及其电子雾化设备
CN114965728A (zh) * 2021-02-18 2022-08-30 塞莫费雪科学（不来梅）有限公司 用数据非依赖性采集质谱分析生物分子样品的方法和设备
CN114965728B (zh) * 2021-02-18 2024-04-12 塞莫费雪科学（不来梅）有限公司 用数据非依赖性采集质谱分析生物分子样品的方法和设备

Also Published As

Publication number Publication date
WO2007144606A2 (en) 2007-12-21
WO2007144606A3 (en) 2008-04-03
MX2008015158A (es) 2009-04-30
KR20090068199A (ko) 2009-06-25
JP2009540319A (ja) 2009-11-19
CA2651934A1 (en) 2007-12-21
GB0611669D0 (en) 2006-07-19
AU2007258970A1 (en) 2007-12-21
EP2035829A2 (en) 2009-03-18
BRPI0711967A2 (pt) 2012-01-24

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Application publication date: 20091223