CN101611313A - 质谱法生物标记测定 - Google Patents

质谱法生物标记测定 Download PDF

Info

Publication number
CN101611313A
CN101611313A CNA2007800219002A CN200780021900A CN101611313A CN 101611313 A CN101611313 A CN 101611313A CN A2007800219002 A CNA2007800219002 A CN A2007800219002A CN 200780021900 A CN200780021900 A CN 200780021900A CN 101611313 A CN101611313 A CN 101611313A
Authority
CN
China
Prior art keywords
biomarker
signal
sample
quality
msba
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2007800219002A
Other languages
English (en)
Chinese (zh)
Inventor
西村俊秀
荻原淳
川村猛
T·卡瓦卡米
京野完
金泽光洋
F·尼贝里
G·马科-瓦加
安养寺久荣
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca UK Ltd
Medical Proteoscope Co Ltd
Original Assignee
AstraZeneca UK Ltd
Medical Proteoscope Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca UK Ltd, Medical Proteoscope Co Ltd filed Critical AstraZeneca UK Ltd
Publication of CN101611313A publication Critical patent/CN101611313A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/74Optical detectors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • G01N30/7233Mass spectrometers interfaced to liquid or supercritical fluid chromatograph

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
CNA2007800219002A 2006-06-13 2007-06-13 质谱法生物标记测定 Pending CN101611313A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0611669.3A GB0611669D0 (en) 2006-06-13 2006-06-13 Mass spectrometry biomarker assay
GB0611669.3 2006-06-13

Publications (1)

Publication Number Publication Date
CN101611313A true CN101611313A (zh) 2009-12-23

Family

ID=36745797

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2007800219002A Pending CN101611313A (zh) 2006-06-13 2007-06-13 质谱法生物标记测定

Country Status (10)

Country Link
EP (1) EP2035829A2 (fr)
JP (1) JP2009540319A (fr)
KR (1) KR20090068199A (fr)
CN (1) CN101611313A (fr)
AU (1) AU2007258970A1 (fr)
BR (1) BRPI0711967A2 (fr)
CA (1) CA2651934A1 (fr)
GB (1) GB0611669D0 (fr)
MX (1) MX2008015158A (fr)
WO (1) WO2007144606A2 (fr)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102201039A (zh) * 2010-08-19 2011-09-28 上海聚类生物科技有限公司 一种分析ltq数据的方法
CN107683476A (zh) * 2015-05-29 2018-02-09 英国质谱公司 样品质谱分析
CN108427002A (zh) * 2017-02-13 2018-08-21 萨默费尼根有限公司 生成用于靶向质谱分析的包含列表的方法
CN109416360A (zh) * 2016-03-31 2019-03-01 迪森德克斯公司 生物标志物数据库的生成和用途
CN109477840A (zh) * 2016-05-24 2019-03-15 因欧沃私人有限责任公司 用于在卵内非破坏性地确定家禽性别的方法和系统
CN109863239A (zh) * 2016-08-19 2019-06-07 莫纳什大学 用于病原体的鉴定和定量的光谱学系统和方法
CN111316106A (zh) * 2017-09-05 2020-06-19 迪森德克斯公司 自动化样品工作流程门控和数据分析
CN111479464A (zh) * 2017-12-22 2020-07-31 阿西姆普托特有限公司 与用于生物样品的冷却条件相关的方法和系统
CN111672658A (zh) * 2020-06-08 2020-09-18 深圳市康泓威科技有限公司 电子雾化设备最佳雾化温度的检测与控制方法及其电子雾化设备
CN112424825A (zh) * 2018-05-15 2021-02-26 文塔纳医疗系统公司 染色聚集体中信号的定量
CN114965728A (zh) * 2021-02-18 2022-08-30 塞莫费雪科学(不来梅)有限公司 用数据非依赖性采集质谱分析生物分子样品的方法和设备

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9793100B2 (en) * 2008-07-23 2017-10-17 Samir Al Moussalami Portable plasma based diagnostic apparatus and diagnostic method
GB0906698D0 (en) 2009-04-17 2009-06-03 Queen Mary & Westfield College Method for quantifying modified peptides
KR101144237B1 (ko) * 2009-12-29 2012-05-11 한국기초과학지원연구원 고분해능 질량분석법과 약리활성검사를 이용한 천연물의 약리 활성물질 발굴 방법
GB201006360D0 (en) * 2010-04-16 2010-06-02 Immatics Biotechnologies Gmbh Method for differentially quantifying naturally processed HLA-restricted peptides for cancer, autoimmune and infectious diseases immunotherapy development
US9141756B1 (en) 2010-07-20 2015-09-22 University Of Southern California Multi-scale complex systems transdisciplinary analysis of response to therapy
GB201204278D0 (en) 2012-03-09 2012-04-25 Queen Mary & Westfield College Method
FR3016461B1 (fr) * 2014-01-10 2017-06-23 Imabiotech Procede de traitement de donnees d'imagerie moleculaire et serveur de donnees correspondant
DE102014000646B4 (de) * 2014-01-17 2023-05-11 Bruker Daltonics GmbH & Co. KG Massenspektrometrische Resistenzbestimmung durch Metabolismus-Messung
JP6613490B2 (ja) * 2016-02-19 2019-12-04 国立大学法人 宮崎大学 腺癌の検出方法
CA3101968A1 (fr) * 2017-06-29 2019-01-03 Quanticision Diagnostics Canada, Inc. Appareil et procede de quantification absolue de biomarqueurs permettant un diagnostic de tumeur solide
JP2020532732A (ja) 2017-09-01 2020-11-12 ヴェン バイオサイエンシズ コーポレーション 診断および治療モニタリングのためのバイオマーカーとしての糖ペプチドの同定および使用
EP3884281A4 (fr) * 2018-11-23 2022-08-24 Agency for Science, Technology and Research Procédé d'identification d'un échantillon biologique inconnu à partir de multiples attributs
KR102632163B1 (ko) 2022-04-13 2024-02-01 오보젠 주식회사 가금류 알(卵)의 암수 검사 및 선별장치 그리고 이를 이용한 선별방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1573044A4 (fr) * 2002-12-18 2006-07-05 Ciphergen Biosystems Inc Biomarqueurs seriques du cancer du poumon
DE10324149A1 (de) * 2003-05-26 2004-12-16 Imat-Uve Gmbh Verfahren und Vorrichtung zur GC/MS- oder LC/MS-Screeninganalyse
AU2005231101A1 (en) * 2004-03-30 2005-10-20 Eastern Virginia Medical School Lung cancer biomarkers
US7851742B2 (en) * 2004-05-20 2010-12-14 Waters Technologies Corporation Method and apparatus for identifying proteins in mixtures

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102201039A (zh) * 2010-08-19 2011-09-28 上海聚类生物科技有限公司 一种分析ltq数据的方法
CN107683476A (zh) * 2015-05-29 2018-02-09 英国质谱公司 样品质谱分析
CN109416360A (zh) * 2016-03-31 2019-03-01 迪森德克斯公司 生物标志物数据库的生成和用途
CN109477840B (zh) * 2016-05-24 2022-12-23 因欧沃控股私人有限责任公司 用于在卵内非破坏性地确定家禽性别的方法和系统
CN109477840A (zh) * 2016-05-24 2019-03-15 因欧沃私人有限责任公司 用于在卵内非破坏性地确定家禽性别的方法和系统
CN109863239A (zh) * 2016-08-19 2019-06-07 莫纳什大学 用于病原体的鉴定和定量的光谱学系统和方法
CN108427002B (zh) * 2017-02-13 2021-01-12 萨默费尼根有限公司 生成用于靶向质谱分析的包含列表的方法
CN108427002A (zh) * 2017-02-13 2018-08-21 萨默费尼根有限公司 生成用于靶向质谱分析的包含列表的方法
CN111316106A (zh) * 2017-09-05 2020-06-19 迪森德克斯公司 自动化样品工作流程门控和数据分析
CN111479464A (zh) * 2017-12-22 2020-07-31 阿西姆普托特有限公司 与用于生物样品的冷却条件相关的方法和系统
CN112424825A (zh) * 2018-05-15 2021-02-26 文塔纳医疗系统公司 染色聚集体中信号的定量
CN111672658A (zh) * 2020-06-08 2020-09-18 深圳市康泓威科技有限公司 电子雾化设备最佳雾化温度的检测与控制方法及其电子雾化设备
CN114965728A (zh) * 2021-02-18 2022-08-30 塞莫费雪科学(不来梅)有限公司 用数据非依赖性采集质谱分析生物分子样品的方法和设备
CN114965728B (zh) * 2021-02-18 2024-04-12 塞莫费雪科学(不来梅)有限公司 用数据非依赖性采集质谱分析生物分子样品的方法和设备

Also Published As

Publication number Publication date
EP2035829A2 (fr) 2009-03-18
BRPI0711967A2 (pt) 2012-01-24
JP2009540319A (ja) 2009-11-19
KR20090068199A (ko) 2009-06-25
WO2007144606A3 (fr) 2008-04-03
GB0611669D0 (en) 2006-07-19
CA2651934A1 (fr) 2007-12-21
AU2007258970A1 (en) 2007-12-21
MX2008015158A (es) 2009-04-30
WO2007144606A2 (fr) 2007-12-21

Similar Documents

Publication Publication Date Title
CN101611313A (zh) 质谱法生物标记测定
Veenstra Global and targeted quantitative proteomics for biomarker discovery
Issaq et al. Peer reviewed: SELDI-TOF MS for diagnostic proteomics
US20060269944A1 (en) Mass Intensity profiling system and uses thereof
CN110838340B (zh) 一种不依赖数据库搜索的蛋白质生物标志物鉴定方法
Sokolowska et al. Applications of mass spectrometry in proteomics
CN112305121B (zh) 代谢标志物在动脉粥样硬化性脑梗死中的应用
EP1887351A1 (fr) Procede de criblage pour une proteine specifique dans une analyse detaillee du proteome
CN114624317B (zh) 一种基于直接进样质谱的定性和定量分析方法
CN112305122B (zh) 代谢物标志物及其在疾病中的应用
Khan et al. Proteomics by mass spectrometry—Go big or go home?
Merkley et al. A proteomics tutorial
O'riordan et al. Technology Insight: renal proteomics—at the crossroads between promise and problems
CN101169417A (zh) 用磁珠支持基质及质谱判断正常人与肝癌的试剂盒和方法
CN112630344B (zh) 代谢标志物在脑梗死中的用途
Hachey et al. Proteomics in reproductive medicine: the technology for separation and identification of proteins
CN112147344B (zh) 动脉粥样硬化性脑梗死的代谢标志物及其在诊疗中的应用
Sigdel et al. Interpreting the proteome and peptidome in transplantation
Vaezzadeh et al. Proteomics and opportunities for clinical translation in urological disease
Del Boccio et al. Homo sapiens proteomics: clinical perspectives
Keane et al. Mass spectrometry based proteomics: Changing the impact of protein analysis in forensic science
Fassbender et al. Proteomic biomarkers for endometriosis
Wang et al. SWATH-MS in proteomics: current status
Lottspeich Top down and bottom up analysis of proteins (focusing on quantitative aspects)
Cutillas Analysis of peptides in biological fluids by LC-MS/MS

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20091223