CN101588807B - D-核糖在制备治疗心律失常的药物中的应用 - Google Patents

D-核糖在制备治疗心律失常的药物中的应用 Download PDF

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Publication number
CN101588807B
CN101588807B CN2008800029553A CN200880002955A CN101588807B CN 101588807 B CN101588807 B CN 101588807B CN 2008800029553 A CN2008800029553 A CN 2008800029553A CN 200880002955 A CN200880002955 A CN 200880002955A CN 101588807 B CN101588807 B CN 101588807B
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Prior art keywords
ribose
grams
heart
atrial fibrillation
cardiac arrhythmias
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Chinese (zh)
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CN101588807A (zh
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J·D·赫里克
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Ribek Co
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Bioenergy Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CN2008800029553A 2007-01-23 2008-01-23 D-核糖在制备治疗心律失常的药物中的应用 Active CN101588807B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88194007P 2007-01-23 2007-01-23
US60/881,940 2007-01-23
PCT/US2008/000845 WO2008091618A1 (en) 2007-01-23 2008-01-23 Use of d-ribose to treat cardiac arrhythmias

Publications (2)

Publication Number Publication Date
CN101588807A CN101588807A (zh) 2009-11-25
CN101588807B true CN101588807B (zh) 2012-07-04

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008800029553A Active CN101588807B (zh) 2007-01-23 2008-01-23 D-核糖在制备治疗心律失常的药物中的应用

Country Status (10)

Country Link
US (1) US8101581B2 (cg-RX-API-DMAC7.html)
EP (1) EP2120968B1 (cg-RX-API-DMAC7.html)
JP (1) JP5396387B2 (cg-RX-API-DMAC7.html)
CN (1) CN101588807B (cg-RX-API-DMAC7.html)
AT (1) ATE487485T1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0806231A2 (cg-RX-API-DMAC7.html)
CA (1) CA2674717C (cg-RX-API-DMAC7.html)
DE (1) DE602008003411D1 (cg-RX-API-DMAC7.html)
ES (1) ES2352154T3 (cg-RX-API-DMAC7.html)
WO (1) WO2008091618A1 (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020119933A1 (en) * 2000-07-28 2002-08-29 Butler Terri L. Compositions and methods for improving cardiovascular function
WO2008091618A1 (en) 2007-01-23 2008-07-31 Bioenergy, Inc. Use of d-ribose to treat cardiac arrhythmias
CN106138071A (zh) * 2008-04-02 2016-11-23 生物能公司 核糖在对于急性心肌梗塞的第一反应中的用途
EP4241838A3 (en) 2016-02-01 2023-12-20 Bioenergy Life Science, Inc. Use of ribose for treatment of subjects having congestive heart failure

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US4605644A (en) * 1985-02-07 1986-08-12 Regents Of The University Of Minnesota Method for stimulating recovery from ischemia employing ribose and adenine
US4719201A (en) * 1985-02-07 1988-01-12 Regents Of The University Of Minnesota Method for stimulating recovery from ischemia
US4824660A (en) * 1985-06-06 1989-04-25 Paul S. Angello Method of determining the viability of tissue in an organism
DE4228215A1 (de) * 1992-08-25 1994-03-03 Pliml Wolfgang Verwendung von Ribose zur Herstellung eines Arzneimittels zur Behandlung von Leistungsschwächen des Körpers, insbesondere von Organinsuffizienzen
RU2127548C1 (ru) * 1996-06-26 1999-03-20 Алабовский Владимир Владимирович Способ коронарографии в эксперименте
DE19650754A1 (de) * 1996-12-06 1998-06-10 Wolfgang Dr Pliml Ribose und Schlaganfall
US6218366B1 (en) * 1998-06-19 2001-04-17 Bioenergy, Inc. Method for raising the hypoxic threshold
US6159942A (en) * 1998-06-19 2000-12-12 Bioenergy, Inc. Compositions for increasing energy in vivo
US20020119933A1 (en) * 2000-07-28 2002-08-29 Butler Terri L. Compositions and methods for improving cardiovascular function
US6429198B1 (en) * 1999-04-12 2002-08-06 Bioenergy Inc. Compositions for increasing athletic performance in mammals
US6534480B2 (en) * 1999-06-17 2003-03-18 Bioenergy Inc. Compositions for increasing energy in vivo
US6339716B1 (en) * 1999-09-24 2002-01-15 Bioenergy Inc. Method for determining viability of a myocardial segment
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US6511964B2 (en) * 1999-09-24 2003-01-28 Bioenergy, Inc. Method for treating acute mountain sickness
US6703370B1 (en) * 1999-10-27 2004-03-09 Bioenergy, Inc. Use of ribose to treat fibromyalgia
ATE282310T1 (de) * 1999-12-21 2004-12-15 Viacell Llc Zusammensetzungen zur lagerung von blutplättchen
CA2397707A1 (en) * 2000-01-07 2001-07-19 Susan S. Percival Compositions for enhancing the immune response
US6525027B2 (en) * 2000-01-20 2003-02-25 Bioenergy Inc. Use of ribose supplementation for increasing muscle mass and decreasing body fat in humans
US6420342B1 (en) * 2000-05-08 2002-07-16 N.V. Nutricia Nutritional preparation comprising ribose and medical use thereof
IT1317043B1 (it) * 2000-06-14 2003-05-26 Sigma Tau Healthscience Spa Integratore alimentare potenziante il metabolismo energeticomuscolare, comprendente una alcanoil l-carnitina e ribosio.
US20030212006A1 (en) * 2002-05-13 2003-11-13 Seifert John G. Method for reducing free radical formation in healthy individuals undergoing hypoxic exercise and medical conditions with increased oxygen free radicals
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US7687468B2 (en) * 2003-05-14 2010-03-30 Viacell, LLC. Rejuvenation of stored blood
US8759315B2 (en) * 2003-05-14 2014-06-24 Viacell, Llc Methods for rejuvenating
US20040229205A1 (en) * 2003-05-16 2004-11-18 Ericson Daniel G. Compositions for the storage of platelets
BRPI0506485A (pt) * 2004-01-14 2007-02-13 Bioenergy Inc método para reduzir o tempo de recuperação de um mamìfero submetido a uma anestesia geral, método para aumentar a recuperação de sepsia e uma composição adequada para administração intravenosa
ES2393786T3 (es) * 2004-04-29 2012-12-28 Ribocor, Inc. Método para mejorar la eficacia ventilatoria
US20100099630A1 (en) * 2004-04-29 2010-04-22 Maccarter Dean J Method for improving ventilatory efficiency
DK1800675T3 (da) * 2005-12-23 2011-09-05 Nutricia Nv Sammensætninger omfattende polyumættede fedtsyrer, proteiner og mangan og/eller molybdæn og nucleosider/nucleotider til behandling af demens
US8835396B2 (en) * 2006-12-15 2014-09-16 Bioenergy, Inc. Method and compositions for improving pulmonary hypertension
WO2008091618A1 (en) 2007-01-23 2008-07-31 Bioenergy, Inc. Use of d-ribose to treat cardiac arrhythmias
US20090197819A1 (en) * 2007-03-20 2009-08-06 Clarence Albert Johnson Compositions for improving and repairing skin
US20080312169A1 (en) * 2007-03-20 2008-12-18 Clarence Albert Johnson Cosmetic use of D-ribose
US20090232750A1 (en) * 2008-03-13 2009-09-17 St Cyr John A Compositions for indoor tanning
CN106138071A (zh) * 2008-04-02 2016-11-23 生物能公司 核糖在对于急性心肌梗塞的第一反应中的用途
US20090286750A1 (en) * 2008-05-16 2009-11-19 Kasubick Robert V Use of ribose in lessening the clinical symptoms of aberrant firing of neurons

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
刘平怀等.D-核糖对实验性心肌缺血和心律失常的作用研究.《中国药业》.2005,第14卷(第10期),26－28. *

Also Published As

Publication number Publication date
JP2010526884A (ja) 2010-08-05
DE602008003411D1 (de) 2010-12-23
ATE487485T1 (de) 2010-11-15
WO2008091618A1 (en) 2008-07-31
WO2008091618A8 (en) 2010-04-01
ES2352154T3 (es) 2011-02-16
EP2120968A1 (en) 2009-11-25
EP2120968B1 (en) 2010-11-10
CA2674717C (en) 2015-10-13
US20080176809A1 (en) 2008-07-24
JP5396387B2 (ja) 2014-01-22
US8101581B2 (en) 2012-01-24
BRPI0806231A2 (pt) 2011-09-06
CN101588807A (zh) 2009-11-25
CA2674717A1 (en) 2008-07-31

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Owner name: RIBERK INC.

Free format text: FORMER NAME: BIOENERGY INC.

CP01 Change in the name or title of a patent holder

Address after: The University of Minnesota

Patentee after: Ribek Co.

Address before: The University of Minnesota

Patentee before: Bioenergy Inc.