CN101569778A - Biofeedback simulation system and biofeedback simulation method - Google Patents
Biofeedback simulation system and biofeedback simulation method Download PDFInfo
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Abstract
The invention relates to a biofeedback simulation system and a biofeedback simulation method. The biofeedback simulation system comprises a physiological signal pick device, a central control system, a memory, a physical simulation device and multimedia equipment; the physiological signal pick device is used for picking physiological signals; the memory is used for memorizing multimedia data; the central control system is used for analyzing physiological signals and forming feedback information, reading multimedia data memorized in the memory according to the feedback information, controlling the multimedia equipment to show the read multimedia data, and controlling physical simulation device to implement the physical simulation. The biofeedback simulation system is a fire-new and more efficient rehabilitation iatrotechnique.
Description
[technical field]
The present invention relates to a kind of biofeedback stimulating system and biofeedback stimulating method.
[background technology]
At present, the drug addiction treatment method that generally adopts both domestic and external has following four kinds of methods:
(1) natural withdrawal method (claiming cold turkey or dried ring method again).The drugs that are meant forced interruption junkie in the withdrawal are supplied with, and only provide diet to look after with general, make its withdrawal symptom spontaneous regression and reach a kind of drug rehabilitation method of detoxification purpose.Be characterized in not administration, shortcoming is to cause patient's withdrawal painful owing to give up phenomenon.
(2) drug withdrawal method.Be to show junkie to take and give up medicine, with the method that substitutes, successively decreases, slow down, alleviate the misery of junkie withdrawal symptom, reach the drug rehabilitation method of detoxification gradually.Drug-breaking medicine generally is a chemicals, and effect is strong, and toxicity is also strong, use back relapse rate height, and the Western medicine that has itself also has addiction.For example, adopting the weak lifelong Concept of Maintenance of agonist methadone of opiate receptor actual is with the method for drug dependence for drug addiction, not from solving the problem of drug rehabilitation in essence.
(3) non-drug withdrawal method.Be meant and adopt acupuncture, physiotherapy table etc. to alleviate a kind of drug rehabilitation method of junkie withdrawal symptom reaction.The method by supplementary means and " psychological hint " of being characterized in alleviates junkie withdrawal symptom misery and reaches the detoxification purpose.As Han Shi withdrawal instrument, activate body endogenous opiate system when utilizing stimulating acupoint, impel the release endogenous opiatepeptide, to replace the function of exogenous morphine, the analgesic activity of performance general is eliminated withdrawal symptom.Narrow spectrum low-frequency electrical stimulation pulse physics detoxification treatment is difficult to spend the peak platform of detoxification.And the treatment source as electrotherapy is relatively more chaotic at present, and stimulus parameter differs greatly, and also lacking stimulates the detection means of back to patient physiological information, so unsatisfactory curative effect.
(4) operation drug rehabilitation.By the neurosurgery horseley-Clarke technique, destroy interior certain or certain the several nuclears of brain selectively and roll into a ball the nerve fiber conductive beam, reach the purpose of rehabilitating addicts.Because this damage is irreversible, can not expect to people's harm, often produces serious adverse and sequela.
[summary of the invention]
In view of this, be necessary, a kind of brand-new and effective more biofeedback stimulating system is provided at the existing problem of above-mentioned various drug addiction treatment methods.
A kind of biofeedback stimulating system comprises physiology signal acquisition device, central control system, memorizer, physical stimulation device and multimedia equipment; Described physiology signal acquisition device is used to gather physiological signal; Described memorizer is used to store multi-medium data; Described central control system is used for feedback information is analyzed and formed to physiological signal, read the multi-medium data of memory stores according to described feedback information, the control multimedia equipment represents the multi-medium data that reads, and control physical stimulation device is implemented physical stimulation.
Preferably, described physiology signal acquisition device is one or more in eeg signal acquisition device, myoelectric sensor, pulses measure device, nuclear magnetic resonance analyser, electrocardiograph and the sphygomanometer.
Preferably, described physical stimulation device be a deep brain nuclear group electrical stimulation device, in cranium repeatability low frequency magnetic stimulating device and device for laser therapy one or more.
Preferably, described multimedia equipment is one or more among display device, stereo set, game station and the human-computer interaction device.
Preferably, described central control system, memorizer and multimedia equipment are realized by computer system.
Preferably, described multi-medium data comprises video, the audio frequency multimedia file that animal capable obtains.
Preferably, described multi-medium data comprises video, audio frequency, recreation multimedia file.
Preferably, described multimedia file has personalization features.
In addition, also provide a kind of biofeedback stimulating method.
A kind of biofeedback stimulating method comprises: represent multimedia messages; Gather physiological signal; Analyze physiological signal, and form feedback information; Continue to represent current multimedia messages or change current multimedia messages according to feedback information, and implement physical stimulation.
Preferably, described multimedia messages is one or more in video, audio frequency and the recreation.
Preferably, described physiological signal is one or more in EEG signals, the muscle signal of telecommunication, heart rate, functional magnetic resonance resonance image-forming information, electrocardiosignal and the blood pressure.
Preferably, described physical stimulation is one or more in electricity irritation, magnetic stimulation and the photostimulation.
Above-mentioned biofeedback stimulating system and biofeedback stimulating method influence patient's brain by representing multimedia messages, and form new power rule formula to help the patient by physical stimulation, make organismic internal environment produce new stablizing, therefore withdrawal can obviously reduce patient's relapse rate and shorten treatment time the psychological dependence of drugs.Above-mentioned biofeedback stimulating system and biofeedback stimulating method obviously are different from existing drug addiction treatment method, are a kind of brand-new and effective more drug addiction treatment technology.
[description of drawings]
Fig. 1 is the sketch map of first embodiment of biofeedback stimulating system.
Fig. 2 is the sketch map of second embodiment of biofeedback stimulating system.
Fig. 3 is the sketch map of the 3rd embodiment of biofeedback stimulating system.
Fig. 4 is the sketch map of device for laser therapy first embodiment.
Fig. 5 is the sketch map of blue laser.
Fig. 6 is the sketch map of Yellow light laser.
Fig. 7 is the sketch map of beam condensing unit.
Fig. 8 is the sketch map that optical fiber treating device uses on human body.
Fig. 9 is the amplification inclinating view of optical fiber emanator.
Figure 10 is the amplification inclinating view of optical fiber integrator.
Figure 11 is the sketch map of laser irradiation cell.
Figure 12 is the neuronic sketch map that laser irradiation has imported the light sensation gene.
Figure 13 is the graph of a relation that brings out current potential and laser pulse.
Figure 14 is the sketch map of device for laser therapy second embodiment.
[specific embodiment]
According to the biofeedback principle, brain and whole machine body are accepted and process information is to carry out according to certain power rule formula.Power rule formula is that the individual back of giving birth to produces under the various information effect and forms.Under the effect of " information → reaction ", new power rule formula can appear, and it can be " useful " or " deleterious " to body, as disease, custom, way of act etc.The consume illegal drugs addiction is also advised formula because the psychology of junkie and behavior have formed a kind of deleterious power except that because of the physiological need.After the physiology drug rehabilitation, psychological drug addiction is hidden difficulty in the hiding and is gone, and very easily takes place " reviving ".Can wake demand once more up because of the old old reaction of information recurrence to drugs.The principle of biofeedback stimulating system is exactly the brain that influences junkie, forms new power rule formula with benign information, makes organismic internal environment produce new stablizing, and gives up the psychological dependence of drugs.
Fig. 1 is the sketch map of first embodiment of biofeedback stimulating system.Biofeedback stimulating system 100 comprises physiology signal acquisition device 101, central control system 102, memorizer 103, physical stimulation device 104 and multimedia equipment 105.
Physiology signal acquisition device 101 is used to gather various physiological signals.Physiology signal acquisition device 101 can be one or more in eeg signal acquisition device, myoelectric sensor, pulses measure device, nuclear magnetic resonance analyser, electrocardiograph and the sphygomanometer.The eeg signal acquisition device is used for gathering and analyzing EEG signals, myoelectric sensor is used to gather the muscle signal of telecommunication, the pulses measure device is used for the monitored patient heart rate, nuclear magnetic resonance analyser is used to gather the functional magnetic resonance resonance image-forming information of patient's brain, electrocardiograph is used for record and analyzes electrocardiosignal, and sphygomanometer is used for monitoring in real time the situation of change of blood pressure.
Central control system 102 is used for feedback information is analyzed and formed to physiological signal, reads the data of memorizer 103 storages, control physical stimulation device 104 and multimedia equipment 105 work.
Memorizer 103 is used to store multi-medium data.Memorizer 103 can be storage mediums such as hard disk, flash memory, CD.
Physical stimulation device 104 is used for biology is implemented physical stimulation.Physical stimulation device 104 can be electrical stimulation device (the Deep brain stimulation of deep brain nuclear group, DBS), through cranium repeatability low frequency magnetic stimulating device (Transcranial Magnetic Stimulation, one or more TMS) and in the device for laser therapy.
Deep brain nuclear group electrical stimulation device is to utilize brain stereotactic operation a certain specific position implant electrode in brain, produces pulse by stimulus generator, and brain deep nerve nucleus is carried out chronic electrical stimulation.This method is not destroyed cerebral tissue and nervous tissue, is reversible, can adjust stimulus intensity and frequency external.
Through cranium repeatability low frequency magnetic stimulating device is a kind of AT electrophysiological technique that neurocyte is stimulated in the brain outside.The action principle that stimulates through cranium repeatability low frequency magnetic is to produce transient magnetic field with a fast current pulse, and skull is passed in this magnetic field, causes that contiguous nervous tissue produces the secondary electric current, the neurocyte depolarization, thus generation stimulates or the electrical activity of blocking-up cerebral tissue.Stimulating through cranium repeatability low frequency magnetic is a kind of noinvasive, painless, safe new technique, and multiple central nervous system disease is all had certain curative effect.
Device for laser therapy is to utilize laser instrument to send blueness or yellow laser, blueness or yellow laser are deep in the cortex in the skull by optical fiber and shine, blueness or yellow laser only work to the cell that has imported the photaesthesia gene, therefore, this device for laser therapy has cell-specific and can effectively activate or suppress neuron.Before using device for laser therapy, need be with photaesthesia gene (excited type channel protein gene (Channelrhodopsin-2, ChR2), inhibition type channel protein gene (Helorhodopsin, NpHR)) be transferred to by special promoter and the neuron of the drug craving associated loop of reverting to take drugs in and express.Device for laser therapy changes in brain and has the neuron of photaesthesia gene that photostimulation is provided by burying optical fiber in the brain, causes neuronic excitement or inhibition thus.Specifically, express the neuron that the excited type channel protein gene is arranged with the blue light stimulation, with such neuron of excitement; Stimulate expression that the neuron of inhibition type channel protein gene is arranged with gold-tinted, will suppress such neuron.By neural circuit excited or that inhibition just can be regulated and control to revert to take drugs, thereby reduce relapse rate.This photaesthesia gene neuromodulation technology has higher spatial and temporal resolution (temporal resolution is accurate to certain class neuron in the ms level on the space).
The stimulus parameter of above-mentioned physical stimulation is regulated and control by central control system 102.These parameters comprise the frequency (Hz), intensity (V), time-histories (ms or s) of stimulation, (ms or s) etc. at interval.
Multimedia equipment 105 is used to represent multimedia messages.Multimedia equipment 105 can be one or more among display device, stereo set, game station and the human-computer interaction device.
Central control system 102, memorizer 103 and multimedia equipment 105 can be realized by computer system.
Fig. 2 is the sketch map of second embodiment of biofeedback stimulating system.This biofeedback stimulating system 200 is mainly used in animal experiment study.Laboratory animal is chosen the animal model (for example monkey) of reverting to take drugs after classical drug dependence is given up.This biofeedback stimulating system 200 comprises eeg signal acquisition device 201, central control system 202, memorizer 203, deep brain nuclear group electrical stimulation device 204, device for laser therapy 205, display device 207 and stereo set 206.The multi-medium data of memorizer 203 storage comprises multimedia files (such as video recordings such as color, food, the contentions of copulation power) such as video that animal capable obtains, audio frequency.
When biofeedback stimulating system 200 was started working, central control system 202 at first read multimedia file from memorizer 203, control display device 207 display images, and control stereo set 206 plays sound.The brain central nervous system is caught and entered to these audio/video informations by the animal sense organ, forms neural impulse, produces brain wave thus.Eeg signal acquisition device 201 is gathered EEG signals by the recording electrode that sticks on the animal scalp, and the EEG signals of gathering is sent to central control system 202.Feedback information is analyzed and formed to 202 pairs of EEG signals of central control system.If it is normal that feedback information shows brain wave, then control display device 207 and the current multimedia file of stereo set 206 continuation broadcasts.If feedback information shows animal and the phenomenon of reverting to take drugs occurs, then change current multimedia messages, and give one or more physical stimulations simultaneously.The multimedia messages that changes can be that audio frequency turns to more intuitive video information, and perhaps more weak information transfers stronger information to.Physical stimulation comprises electricity irritation and photostimulation, and electricity irritation realizes that by deep brain nuclear group electrical stimulation device 204 photostimulation is realized by device for laser therapy 205.
Above-mentioned therapeutic process is a continuous multiple process.Eeg signal acquisition device 201 is gathered the EEG signals of animal in real time, and central control system 202 is tackled new EEG signals of gathering mutually and carried out analyzing and processing, upgrades feedback information.Constantly regulate, feed back re-adjustment thus, constantly deepen the psychological cognition of animal simultaneously, reduce the drug craving of reverting to take drugs, thereby on aggregate level, reduce relapse rate, reach the purpose of thoroughly rehabilitating addicts.
Fig. 3 is the sketch map of the 3rd embodiment of biofeedback stimulating system.This biofeedback stimulating system 300 is mainly used in clinical treatment, and the drug abuse patient is rehabilitated addicts, and can be used for treatment simultaneously and alleviates sacred diseases such as parkinson disease, epileptics, depression and chronic pain.Have characteristics such as the suitability is strong, real-time is high, accuracy is good, powerful.This biofeedback stimulating system 300 comprises eeg signal acquisition device 301, myoelectric sensor 302, pulses measure device 303, nuclear magnetic resonance analyser 304, electrocardiograph 305, sphygomanometer 306, central control system 307, memorizer 311, a deep brain nuclear group electrical stimulation device 308, through cranium repeatability low frequency magnetic stimulating device 310, device for laser therapy 309, display device 313, stereo set 312 and game station 314.The multi-medium data of memorizer 311 storages comprises multimedia files such as video, audio frequency, recreation, these information and drug addiction are closely related, as take drugs can cause going to bits, catch, the breakdown of a family, give up when taking place that health trembles, rolls about etc., and the back family that rehabilitates addicts is harmonious again, lives a happy life etc.This multimedia file can be chosen flexibly at different patients, so this biofeedback stimulating system 300 has the advantage of personalized treatment.
When biofeedback stimulating system 300 was started working, central control system 307 at first read multimedia file from memorizer 311, and control display device 313 display images, control stereo set 312 play sound, control game station 314 running games.These multimedia messages enter the brain central nervous system by human body (eye or ear), and form neural impulse, cause that thus effector organ (as muscle, internal organs, secernent official rank) reacts, and produces a series of physiological changies.Eeg signal acquisition device 301, myoelectric sensor 302, pulses measure device 303, nuclear magnetic resonance analyser 304, electrocardiograph 305 and sphygomanometer 306 are gathered functional magnetic resonance resonance image-forming information, electrocardiosignal and the blood pressure of the EEG signals of human body, the muscle signal of telecommunication, heart rate, patient's brain respectively, these physiological signals all are sent to central control system 307, central control system 307 to these physiological signals screen, analysis-by-synthesis and form feedback information.Situation is normal if feedback information shows patient physiological, then controls display device 313 and continues to show that current images, control stereo set 312 continue to play current sound, and the control game station continues the operation current game.If feedback information shows the patient and the phenomenon of reverting to take drugs occurs, then change current multimedia messages, and give one or more physical stimulations simultaneously.The multimedia messages that changes can be to turn to more intuitive video information by audio frequency, transfers stronger information to by more weak information, as transferring serious consequence with one's family broken up to from the simple harm of taking drugs.Physical stimulation comprises that electricity irritation, magnetic stimulate and photostimulation.Electricity irritation is realized that by deep brain nuclear group electrical stimulation device magnetic stimulates by realizing that through cranium repeatability low frequency magnetic stimulating device photostimulation is realized by device for laser therapy.
Above-mentioned therapeutic process is a continuous multiple process.Various physiology signal acquisition devices are gathered the various physiological signals of human body in real time, and central control system 307 is tackled the new physiological signal of gathering mutually and carried out analyzing and processing, upgrades feedback information.Constantly regulate, feed back re-adjustment thus, constantly deepen patient's psychological cognition simultaneously, reduce the drug craving of reverting to take drugs, thereby on aggregate level, reduce relapse rate, reach the purpose of thoroughly rehabilitating addicts.
The physical stimulation of above-mentioned biofeedback stimulating system is noinvasive or Wicresoft, the patient's is painful less, and, therefore can obviously reduce patient's relapse rate and shorten treatment time owing to gather patient physiological information in real time and in time regulate output information and additional various stimulus by feedback.
Confirm through laboratory and clinical practice, above-mentioned biofeedback stimulating system has fabulous effect to brain and central nervous system's multiple disease, as insomnia, headache, hypomnesis, neurasthenia, hysteria, habitual tic, obsession, hyperkinetic syndrome, extrapyramidal disease, extremity tremble, involutional neurosis, anxiety neurosis, pain therapy, epilepsy, depression, hypertension, altophobia, childhood hyperkinetic syndrome, neural psychological assessment system etc.
In addition, above-mentioned biofeedback stimulating system can also be applied to sports field (for example athlete's muscle accuracy training system, athlete's muscular endurance training system, athletes ' psychological quality training system, athlete's attention training system etc.), education sector (for example network addiction therapy system, psychology scientific research system, Teaching of Psychology system, students psychology quality training system etc.) and special occupation field (for example army and police's mental training system, fireman's mental training system, drug rehabilitation psychotherapy system, system etc. detects a lie).
Below device for laser therapy (205,309) is carried out specific description:
The number of the laser instrument of device for laser therapy, output controller and impulse controller can be 1,2,3 or more.Below be to be that example describes with 2 situation.
Fig. 4 is the sketch map of device for laser therapy first embodiment.The device for laser therapy of first embodiment comprises power supply 10, first laser instrument 11, the first output controller 12, first impulse controller 13, second laser instrument 18, the second output controller 23, second impulse controller 19, beam condensing unit 14, optical fiber treating device 15, outside program controller 20 and central control system 17.Power supply 10 is a rechargable power supplies, and for example chargeable lithium cell once charges and can use at least 5 years.First laser instrument 11 is used to produce first laser, and second laser instrument 18 is used to produce second laser.First laser enters beam condensing unit 14, the second laser through the first output controller 12 and first impulse controller 13 and enters beam condensing unit 14 through the second output controller 23 and second impulse controller 19.Central control system 17 is used to control power supply 10, first laser instrument 11, second laser instrument 18, the first output controller 12, the second output controller 23, first impulse controller 13 and second impulse controller 19, thereby realizes any adjusting of intensity, repetition rate, pulse number and the relative time relation of first laser and second laser.Under the control of central control system 17, first laser and second laser are that timesharing produces, and promptly any time has only a kind of laser to enter beam condensing unit 14.First laser or second laser transfer to optical fiber treating device 15 by first optical fiber (figure does not show) after beam condensing unit 14 is assembled.Optical fiber treating device 15 is decomposed at least two bundle the 3rd laser or the 4th laser with first laser or second laser, and every bundle the 3rd laser or the 4th laser are by one second optical fiber (figure does not show) transmission.This at least two bundle the 3rd laser or the 4th laser are used for lesions position is shone.
The effect of the various instructions (referring to Fig. 4) that central control system 17 is sent is as follows:
1.P11 and P13 is used to control the output of first laser instrument 11, makes the output of first laser instrument 11 adjustable in the 10-50mW scope.
2.P21 and P23 is used to control the output of second laser instrument 18, makes the output of second laser instrument 18 adjustable in the 10-50mW scope.
3.P12 be used to control the repetition rate of the acousto-optic Q-switching of first laser instrument 11.
4.P22 be used to control the repetition rate of the acousto-optic Q-switching of second laser instrument 18.
5.T1 be used to control the luminous persistent period of first laser.
6.T2 be used to control the luminous persistent period of second laser.
In addition, utilize the clock in the central control system 17 can also control the relative time of the luminous and pulse of first, second laser, thereby finally can realize any adjusting of intensity, repetition rate, pulse number and the relative time relation of first, second laser.
Fig. 7 is the sketch map of beam condensing unit 14.Beam condensing unit 14 comprises first plane mirror 31, second plane mirror 32 and convex lens 33.First laser enters convex lens 33, the second laser through first plane mirror 31 and enter convex lens 33 after second plane mirror 32 and 31 reflection of first plane mirror.First laser or the second laser planoconvex lens 33 assemble the back by first fiber-optic transfer to optical fiber treating device 15.
In use, power supply 10, first laser instrument 11, the first output controller 12, first impulse controller 13, second laser instrument 18, the second output controller 23, second impulse controller 19, central control system 17 and beam condensing unit 14 are formed pulse generator.The volume range of pulse generator is 4 cubic centimetres to 72 cubic centimetres.Pulse generator is imbedded near the position the clavicle of human body by operation.
In use, outside program controller 20 is equivalent to a remote controller, is used for opening or closing pulse generator, regulates laser generation parameter.
Fig. 8 is the sketch map that optical fiber treating device uses on human body.Optical fiber treating device 15 comprises optical fiber emanator 405 and optical fiber integrator 406.Optical fiber emanator 405 is connected with at least two second optical fiber 407 with first optical fiber 402.As shown in Figure 9, optical fiber emanator 405 is spherical, and its surface is provided with a macropore 52 and at least two apertures 51, and macropore 52 and at least two apertures 51 are oppositely arranged.Macropore 52 connects first optical fiber 402, and each aperture 51 connects one second optical fiber 407.As shown in figure 10, optical fiber integrator 406 is plate, which is provided with at least two apertures 61.Each aperture 61 can pass through one second optical fiber 407.Optical fiber integrator 406 is used for fixing at least two second relative positions between the optical fiber 407.Like this, many second optical fiber 407 can cover target spot widely.The volume range of optical fiber treating device 15 is 4 cubic millimeters to 50 cubic millimeters, and therefore, optical fiber treating device 15 can be deep in the cortex 408 in the skull 401.
First optical fiber 402 is encased by the sleeve pipe 403 of the about 300-500 μ of diameter m, sleeve pipe 403 whole heeling-ins are in human epidermal, one end of sleeve pipe 403 connects pulse generator, the other end is fixed on the skull 401 by holder 404 in scalp 400, and passes skull 401 (in advance positional punch) and be deep into cortex 408.The length of second optical fiber 407 is adjustable, thereby can control the degree of depth that second optical fiber 407 is deep into cortex 408.
Figure 11 is the sketch map of laser irradiation cell.The scope of 701 expression laser irradiations, 702 expressions have imported the cell of light sensation gene, 703 represent lead-in light sensillary base not because of cell.The light sensation gene can be photaesthesia channel gene or chlG gene, can import in a certain specific cell, tissue or the individuality light sensation gene and great expression by viral vector in the practice.Have only the importing that is mapped to by illumination the cell 702 of light sensation gene just can produce electricity and change and comprise excitement or inhibitory action, and all not lead-in light sensillary bases because of cell 703 and do not receive illumination importing the cell 702 of light sensation gene all unaffected.And, dissimilar light sensation genes a photaesthesia to specific wavelength, for example, the gene pairs sensitive to blue light of photoactivation type ionophorous protein, the gene pairs gold-tinted sensitivity of light inhibition type ionophorous protein.Because the range of exposures of dispersive each the 3rd laser beam or the 4th laser beam is littler, can shine non-specific site on every side, thereby guarantee the accuracy in treatment site.
Figure 12 is the neuronic sketch map that laser irradiation has imported the light sensation gene, and Figure 13 is the graph of a relation that brings out current potential and laser pulse.When laser pulse arrived neuron 801, the dendron 802 of neuron 801 was accepted this photostimulation, and current potential is brought out in neuron 801 one of corresponding generation, brought out current potential and propagated by aixs cylinder 803.As seen from Figure 12, laser pulse 806 one of a correspondence are brought out current potential 805.
Above-mentioned device for laser therapy resolves into the little laser beam of at least two bundles by optical fiber treating device 15 with a branch of big laser beam, and therefore, the area of the lesions position that this device for laser therapy can shine is bigger.And the range of exposures of the little laser beam of every bundle is littler, can not shine non-specific site on every side, thereby has guaranteed the accuracy of this device for laser therapy.In addition, because this device for laser therapy is to be placed in the human body, can carry, therefore, this device for laser therapy is well suited for patient's daily use.
Figure 14 is the sketch map of device for laser therapy second embodiment.The structure of the device for laser therapy of the device for laser therapy of second embodiment and first embodiment is basic identical, and its difference is: the device for laser therapy of second embodiment also comprises record microelectrode 16 and computer 21.Record microelectrode 16 is used to be imbedded in patient's lesions position, be sent to computer 21 with the potential change of record cell and with the potential change of cell, computer 21 is analyzed with behavioristics the information that records by specific software and is tested, and feedback information is sent to central control system 17 by wireless transmission method, central control system 17 corresponding modify laser generation parameters.The diameter of record microelectrode 16 is about 100 microns, and therefore, record microelectrode 16 can be deep in the cortex 408 in the skull 401.
Because the information that record microelectrode 16 is write down is to handle on computer 21, computer 21 can carry out more high-grade analyzing and processing to information, and therefore, the device for laser therapy of second embodiment is studied very helpful to research worker.
The above embodiment has only expressed two or more embodiment of the present invention, and it describes comparatively concrete and detailed, but can not therefore be interpreted as the restriction to claim of the present invention.Should be pointed out that for the person of ordinary skill of the art without departing from the inventive concept of the premise, can also make at least two distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
Claims (12)
1, a kind of biofeedback stimulating system is characterized in that: comprise physiology signal acquisition device, central control system, memorizer, physical stimulation device and multimedia equipment; Described physiology signal acquisition device is used to gather physiological signal; Described memorizer is used to store multi-medium data; Described central control system is used for feedback information is analyzed and formed to physiological signal, read the multi-medium data of memory stores according to described feedback information, the control multimedia equipment represents the multi-medium data that reads, and control physical stimulation device is implemented physical stimulation.
2, biofeedback stimulating system according to claim 1 is characterized in that: described physiology signal acquisition device is one or more in eeg signal acquisition device, myoelectric sensor, pulses measure device, nuclear magnetic resonance analyser, electrocardiograph and the sphygomanometer.
3, biofeedback stimulating system according to claim 1 is characterized in that: described physical stimulation device is a deep brain nuclear group electrical stimulation device, in cranium repeatability low frequency magnetic stimulating device and device for laser therapy one or more.
4, biofeedback stimulating system according to claim 1 is characterized in that: described multimedia equipment is one or more among display device, stereo set, game station and the human-computer interaction device.
5, biofeedback stimulating system according to claim 1, it is characterized in that: described central control system, memorizer and multimedia equipment are realized by computer system.
6, biofeedback stimulating system according to claim 1 is characterized in that: described multi-medium data comprises video, the audio frequency multimedia file that animal capable obtains.
7, biofeedback stimulating system according to claim 1 is characterized in that: described multi-medium data comprises video, audio frequency, recreation multimedia file.
8, biofeedback stimulating system according to claim 1, it is characterized in that: described multi-medium data has personalization features.
9, a kind of biofeedback stimulating method is characterized in that: comprising:
Represent multimedia messages;
Gather physiological signal;
Analyze physiological signal, and form feedback information;
Continue to represent current multimedia messages or change current multimedia messages according to feedback information, and implement physical stimulation.
10, biofeedback stimulating method according to claim 9 is characterized in that: described multimedia messages is one or more in video, audio frequency and the recreation.
11, biofeedback stimulating method according to claim 9 is characterized in that: described physiological signal is one or more in EEG signals, the muscle signal of telecommunication, heart rate, functional magnetic resonance resonance image-forming information, electrocardiosignal and the blood pressure.
12, biofeedback stimulating method according to claim 9 is characterized in that: described physical stimulation is one or more in electricity irritation, magnetic stimulation and the photostimulation.
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