CN103584839A - Pain sense stimulation instrument and implementation method thereof - Google Patents
Pain sense stimulation instrument and implementation method thereof Download PDFInfo
- Publication number
- CN103584839A CN103584839A CN201310593485.5A CN201310593485A CN103584839A CN 103584839 A CN103584839 A CN 103584839A CN 201310593485 A CN201310593485 A CN 201310593485A CN 103584839 A CN103584839 A CN 103584839A
- Authority
- CN
- China
- Prior art keywords
- laser
- dual
- pain
- pain stimulus
- wavelength laser
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Abstract
The invention provides a pain sense stimulation instrument and an implementation method of the pain sense stimulation instrument. The pain sense stimulation instrument comprises a double-wave-length laser module, a laser power supply, a control circuit board, a water cooling machine, a mechanical light path, an infrared imaging monitoring module and a PC. The pain sense stimulation instrument is manufactured based on the principle that different laser wave lengths penetrate through the surface of the human body to act on pain sense nerves of the skin of the human body to generate light and heat to stimulate the pain sense to generate, the measured result is more accurate, a non-contact specificity excitement polymodal nociceptor is utilized, so that the sense strength is adjustable, stimulation is safe without burning the skin or harming the body, the pains of patients are eliminated, the infection probability and the probability that diseases are spread by blood sources are reduced, and the pain sense stimulation instrument has high clinical practical value.
Description
Technical field
The present invention relates to medical apparatus and instruments and its implementation of a kind of system that excites nerve, especially a kind of pain stimulus instrument and its implementation.
Background technology
The pain sensation is the organism sensation that sexual stimulus produces that comes to harm.There is important biological significance.Be the warning system of organism inside, can cause defensive reaction, there is protective effect.The pain sensation, can be divided into dermatodynia, and from deep pain and the Encelialgia in muscle, tendon and joint, they respectively have feature.The pain sensation acquires a certain degree, conventionally can be with certain physiological change and offending emotional response.People's the pain sensation or pain reaction have larger individual difference.Someone pain susceptibility is low, has people Ze Gao.The individual difference that the pain sensation is larger has much relations with the psychological factor that produces the pain sensation.The pain sensation is also existing certain difference aspect nationality, sex, age.
Visible, organism feels to exist individual variation for pain, in some clinical researches, diagnosis and therapeutic process, for example, analgesic, anesthesia therapeutic evaluation, the mechanism research of charcot marie tooth neuropathic pain, use Laser evoked potentials technology and the intervention of pain intuition to carry out integral body sleep and the sleep study of eyeball fast moving, the aspect such as intravertebral anesthesia and nerve block anesthesia, by the stimulation to organism pain nerve, utilize the impression of its pain to make objective and to have an assessment of directive significance dosage, therapeutic effect etc.
Present stage, the method of organism being carried out to pain stimulus mainly comprises: needle point method, electrostimulation and thermal source stimulus method, yet, needle point method often causes patient to experience inaccurate impact to pain stimulation because acupuncture dynamics is non-constant, electrostimulation and thermal source stimulus method make to stimulate area large, stimulate the degree of depth to be difficult to control, thereby can not accurately stimulate and need stimulation location.Therefore, study a kind of new pain stimulus device, in safety, stimulate the organic measurement result accurately that simultaneously obtains, will there is very important clinical research and be worth.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of pain stimulus instrument.
Another technical problem to be solved by this invention is to provide the implementation method of above-mentioned pain stimulus instrument.
For solving the problems of the technologies described above, technical scheme of the present invention is:
An instrument, comprises dual-wavelength laser module, Laser Power Devices, control circuit board, water cooling unit, mechanical light path, infrared imaging monitoring modular and PC, wherein,
Dual-wavelength laser module, is mainly coupled to form by fiber coupler by 980nm laser instrument (generation pulse current) and 1940nm laser instrument (generation continuous current);
Laser Power Devices, with dual-wavelength laser module connection;
Water cooling unit, is that cooling water is supplied with in the circulation of water-cooled platform by water-cooled interface, and described dual-wavelength laser module is placed on water-cooled platform and carries out glue with indium and connects and heat conduction;
Control circuit board, is DAQ V1.0 data collecting card, by IO delivery outlet, is connected with 15 pin control ports of Laser Power Devices with DA delivery outlet, and to control the parameters such as energy, pulsewidth and cycle of Laser output, described control circuit board of while and water cooling unit control connection;
Machinery light path, by band, protecting armour optical fiber, collimating mirror and mirror holder forms, described band protects armour optical fiber and connects dual-wavelength laser module, by band, protect the light-output that armour optical fiber produces dual-wavelength laser module, and at this band, protect armour optical fiber connector and be fixed with collimating mirror by mirror holder, the beam quality while guaranteeing to irradiate by collimating mirror;
Infrared imaging monitoring modular, is comprised of infrared imaging monitor and PLC communication module connection, for the temperature signal detecting is returned to PC with the form of 4 hexadecimal digits, as calculated afterwards for alarm or control laser power;
PC, with the PLC communication module connection of infrared imaging monitoring modular, simultaneously this PC and control circuit board connection.
Preferably, above-mentioned pain stimulus instrument, described dual-wavelength laser module also comprises indication light source, by the semiconductor laser light resource of a 632nm and LED lamp, the mode with coupling fiber forms described indication light source.
Preferably, above-mentioned pain stimulus instrument, described dual-wavelength laser module is that dual-wavelength laser module is connected with five pin aviation sockets with 232 interfaces by wire with Laser Power Devices line connection, a quasi-continuous semiconductor laser power supply J-QCW4212(pulse current) and a uninterruptable power J-CW5006(continuous current) Power supply line be integrated in aviation plug, by connecting described five pin aviation sockets, to dual-wavelength laser module, power.
Preferably, above-mentioned pain stimulus instrument, the BILON-T-1001 water cooling unit that described water cooling unit is 800W.
Preferably, above-mentioned pain stimulus instrument, is also provided with adnexa on the mirror holder of described mechanical light path, and described adnexa is included as the blower fan with filter screen dustproof and that design, dust cover and is the added attenuator of control light path, optics wedge and micro-step motor connector.
Preferably, above-mentioned pain stimulus instrument, the model of described infrared imaging monitor is online monitor WX-150.
Preferably, above-mentioned pain stimulus instrument, the model of described PLC communication module is Mitsubishi PLC communication module FX1N-485-BD FX3U-485-BD FX2N.
Above-mentioned pain stimulus instrument carries out the implementation method of laser stimulation to organism, concrete steps are as follows:
LEPS pattern (laser evoked potentials, Laser evoked potentials, the pattern of utilizing pulse laser evoked brain potential) under, system initialization, carry out pulse width, the initial setting up of pulse frequency and pulse energy also checks hydraulic pressure protection, whether original state is normal, utilize outer signal controlling output pulse waveform frequently, and start timing in the moment that starts output, and send synchronization pulse to electroencephalograph, by electroencephalograph, on each time point, recorded the EEG signals detecting, and when LEPS finishes by the signal storage detecting to PC, conveniently carry out computing, and/or
(1) CHEP pattern (Contact heat evoked potentials, contact thermostimulation pattern, with heat dish, to carry out the pattern of thermostimulation, here refer to that the laser with continuous wave output stimulates, the mode that the temperature curve of simulation CHEP stimulates) under, system initialization, mainly to carry out preset temperature and the setting of temperature rise time, by these two numerical value, through converting, by experiment, determined the corresponding relation of laser power and temperature value, preset temperature and temperature rise time are found out to corresponding baseline laser power and boost pulse laser power, determine Output of laser pattern, obtain needing the laser output power of modulation, meanwhile, also need to carry out the detection of original state,
(2) under CHEP pattern, utilize the illuminated tested surface of infrared imaging monitor test temperature, and temperature value is sent to PC, and then regulation and control control circuit board, according to temperature rise speed and surface temperature, the power that improves or reduce Output of laser, the time, the intensity that finally reach pain stimulus are controlled effect.
The invention has the beneficial effects as follows:
Above-mentioned pain stimulus instrument, according to different optical maser wavelength, penetrating human body surface acts on the principle that human body skin pain nerve produces photo-thermal thorn Severe Pain and makes, make measurement result more accurate, adopt the excited nociceptor of non-contacting mode specificity, sensation intensity is adjustable, when safety stimulates, can also can not produce injury to health by skin ambustion, has eliminated patient's misery, the probability that has reduced infection and Blood spread disease, has high clinical application.
Accompanying drawing explanation
Fig. 1 is the structure annexation block diagram of pain stimulus instrument of the present invention;
Fig. 2 is that pain stimulus instrument of the present invention carries out the workflow diagram of laser stimulation to organism.
The specific embodiment
In order to make those skilled in the art better understand technical scheme of the present invention, below in conjunction with the drawings and the specific embodiments, technical scheme of the present invention is described in further detail.
Embodiment 1
As shown in Figure 1, a kind of pain stimulus instrument, comprises the BILON-T-1001 water cooling unit of dual-wavelength laser module, Laser Power Devices, control circuit board, 800W, mechanical light path, infrared imaging monitoring modular and PC, wherein,
Dual-wavelength laser module, mainly by the 1940nm laser instrument (generation continuous current) of the quasi-continuous 980nm laser instrument of 150W (generation pulse current) and 3 5W independently, by fiber coupler, be coupled to form, simultaneously, also have indication light source, by the semiconductor laser light resource of a 632nm and green LED lamp, the mode with coupling fiber forms described indication light source;
Laser Power Devices, with dual-wavelength laser module connection, connected mode is that dual-wavelength laser module is connected with five pin aviation sockets with 232 interfaces by wire, the Power supply line of a quasi-continuous semiconductor laser power supply J-QCW4212 and a uninterruptable power J-CW5006 is integrated in aviation plug, by connecting described five pin aviation sockets, to dual-wavelength laser module, powers;
Water cooling unit, is that cooling water is supplied with in the circulation of water-cooled platform by water-cooled interface, and described dual-wavelength laser module is placed on water-cooled platform and carries out glue with indium and connects and heat conduction;
Control circuit board, is DAQ V1.0 data collecting card, by IO delivery outlet, is connected with 15 pin control ports of Laser Power Devices with DA delivery outlet, and to control the parameters such as energy, pulsewidth and cycle of Laser output, described control circuit board of while and water cooling unit control connection;
Machinery light path, by band, protecting armour optical fiber, collimating mirror and mirror holder forms, described band protects armour optical fiber and connects dual-wavelength laser module, by band, protect the light-output that armour optical fiber produces dual-wavelength laser module, and at this band, protect armour optical fiber connector and be fixed with collimating mirror by mirror holder, the beam quality while guaranteeing to irradiate by collimating mirror; In addition, on the mirror holder of described mechanical light path, adnexa can also be set, described adnexa is included as the blower fan with filter screen dustproof and that design, dust cover and is the added attenuator of control light path, optics wedge and micro-step motor connector;
Infrared imaging monitoring modular, by infrared imaging monitor and Mitsubishi PLC communication module FX1N-485-BD FX3U-485-BD FX2N connection, formed, wherein, the model of described infrared imaging monitor is online monitor WX-150, PLC communication module returns to PC for the temperature signal that infrared imaging monitor is detected with the form of 4 hexadecimal digits, as calculated afterwards for alarm or control laser power;
PC, with the PLC communication module connection of infrared imaging monitoring modular, simultaneously this PC and control circuit board connection.
As shown in Figure 2, above-mentioned pain stimulus instrument carries out the implementation method of laser stimulation to organism, and concrete steps are as follows:
LEPS pattern (laser evoked potentials, Laser evoked potentials, the pattern of utilizing pulse laser evoked brain potential) under, system initialization, carry out pulse width, the initial setting up of pulse frequency and pulse energy also checks hydraulic pressure protection, whether original state is normal, utilize outer signal controlling output pulse waveform frequently, and start timing in the moment that starts output, and send synchronization pulse to electroencephalograph, by electroencephalograph, on each time point, recorded the EEG signals detecting, and when LEPS finishes by the signal storage detecting to PC, conveniently carry out computing, and/or
(1) CHEP pattern (Contact heat evoked potentials, contact thermostimulation pattern, with heat dish, to carry out the pattern of thermostimulation, here refer to that the laser with continuous wave output stimulates, the mode that the temperature curve of simulation CHEP stimulates) under, system initialization, mainly to carry out preset temperature and the setting of temperature rise time, by these two numerical value, through converting, by experiment, determined the corresponding relation of laser power and temperature value, preset temperature and temperature rise time are found out to corresponding baseline laser power and boost pulse laser power, determine Output of laser pattern, obtain needing the laser output power of modulation, meanwhile, also need to carry out the detection of original state,
(2) under CHEP pattern, utilize the illuminated tested surface of infrared imaging monitor test temperature, and temperature value is sent to PC, and then regulation and control control circuit board, according to temperature rise speed and surface temperature, the power that improves or reduce Output of laser, the time, the intensity that finally reach pain stimulus are controlled effect.
Because the penetration depth of 976nm laser in skin is darker, can under the pattern of injured skin not, produce heat stimulates darker pain sensation impression; 1940nm laser is an absworption peak on the water, just be absorbed and stimulate to depths heat by conduction skin table is shallow, in the dual-wavelength laser module of described pain stimulus instrument, the generation of dual-wavelength laser adopts 1940nm continuous laser and frequency multiplication to obtain 976nm pulse laser, stimulates the Pain receptor that table is shallow.Due to energy, the burst length is adjustable, therefore the control that the pain sensation is brought out to signal can be carried out more accurate, the high duplication in the situation that.And the temperature that can control irradiating surface by dual-wavelength laser regulates (above-mentioned several temperature are that the pain sensation is experienced the threshold value that receptor is activated) in 43 ℃, 48 ℃ and 52 ℃ of these intervals, thereby can control, stimulate respectively Pain receptor A δ fiber and C fiber, in this judgement at clinical disease and basic research, there is higher practical value.
Above-mentioned detailed description of this kind of pain stimulus instrument and its implementation being carried out with reference to the specific embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not depart under general plotting of the present invention, within should belonging to protection scope of the present invention.
Claims (8)
1. a pain stimulus instrument, is characterized in that: comprise dual-wavelength laser module, Laser Power Devices, control circuit board, water cooling unit, mechanical light path, infrared imaging monitoring modular and PC, wherein,
Dual-wavelength laser module, is mainly coupled to form by fiber coupler by 980nm laser instrument and 1940nm laser instrument;
Laser Power Devices, with dual-wavelength laser module connection;
Water cooling unit, is that cooling water is supplied with in the circulation of water-cooled platform by water-cooled interface, and described dual-wavelength laser module is placed on water-cooled platform and carries out glue with indium and connects and heat conduction;
Control circuit board, is DAQ V1.0 data collecting card, is connected, simultaneously described control circuit board and water cooling unit control connection by IO delivery outlet with DA delivery outlet with 15 pin control ports of Laser Power Devices;
Machinery light path, by band, protecting armour optical fiber, collimating mirror and mirror holder forms, described band protects armour optical fiber and connects dual-wavelength laser module, by band, protecting armour optical fiber derives the laser of dual-wavelength laser module generation, and at this band, protect armour optical fiber connector and be fixed with collimating mirror by mirror holder, the beam quality while guaranteeing to irradiate by collimating mirror;
Infrared imaging monitoring modular, is comprised of infrared imaging monitor and PLC communication module connection, for the temperature signal detecting is returned to PC with the form of 4 hexadecimal digits, as calculated afterwards for alarm or control laser power;
PC, with the PLC communication module connection of infrared imaging monitoring modular, simultaneously this PC and control circuit board connection.
2. pain stimulus instrument according to claim 1, is characterized in that: described dual-wavelength laser module also comprises indication light source, and by the semiconductor laser light resource of a 632nm and LED lamp, the mode with coupling fiber forms described indication light source.
3. pain stimulus instrument according to claim 1, it is characterized in that: described dual-wavelength laser module is that dual-wavelength laser module is connected with five pin aviation sockets with 232 interfaces by wire with Laser Power Devices line connection, the Power supply line of a quasi-continuous semiconductor laser power supply J-QCW4212 and a uninterruptable power J-CW5006 is integrated in aviation plug, by connecting described five pin aviation sockets, to dual-wavelength laser module, powers.
4. pain stimulus instrument according to claim 1, is characterized in that: the BILON-T-1001 water cooling unit that described water cooling unit is 800W.
5. pain stimulus instrument according to claim 1, it is characterized in that: on the mirror holder of described mechanical light path, be also provided with adnexa, described adnexa is included as the blower fan with filter screen dustproof and that design, dust cover and is the added attenuator of control light path, optics wedge and micro-step motor connector.
6. pain stimulus instrument according to claim 1, is characterized in that: the model of described infrared imaging monitor is online monitor WX-150.
7. pain stimulus instrument according to claim 1, is characterized in that: the model of described PLC communication module is Mitsubishi PLC communication module FX1N-485-BD FX3U-485-BDFX2N.
8. the described pain stimulus instrument of one of claim 1-7 carries out the implementation method of laser stimulation to organism, it is characterized in that: concrete steps are as follows:
Under LEPS pattern, system initialization, carry out pulse width, the initial setting up of pulse frequency and pulse energy also checks hydraulic pressure protection, and whether original state is normal, utilizes outer signal controlling output pulse waveform frequently, and start timing and send synchronization pulse to electroencephalograph in the moment that starts output, by electroencephalograph, on each time point, recorded the EEG signals detecting, and when LEPS finishes by the signal storage detecting to PC, conveniently carry out computing; And/or
(1) under CHEP pattern, system initialization, mainly to carry out preset temperature and the setting of temperature rise time, by these two numerical value, through converting, by experiment, determined the corresponding relation of laser power and temperature value, preset temperature and temperature rise time are found out to corresponding baseline laser power and boost pulse laser power, determine Output of laser pattern, obtain needing the laser output power of modulation; Meanwhile, also need to carry out the detection of original state;
(2) under CHEP pattern, utilize the illuminated tested surface of infrared imaging monitor test temperature, and temperature value is sent to PC, and then regulation and control control circuit board, according to temperature rise speed and surface temperature, the power that improves or reduce Output of laser, the time, the intensity that finally reach pain stimulus are controlled effect.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310593485.5A CN103584839B (en) | 2013-11-21 | 2013-11-21 | A kind of pain sense stimulation instrument and its implementation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310593485.5A CN103584839B (en) | 2013-11-21 | 2013-11-21 | A kind of pain sense stimulation instrument and its implementation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103584839A true CN103584839A (en) | 2014-02-19 |
| CN103584839B CN103584839B (en) | 2015-08-26 |
Family
ID=50075317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310593485.5A Expired - Fee Related CN103584839B (en) | 2013-11-21 | 2013-11-21 | A kind of pain sense stimulation instrument and its implementation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103584839B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105456024A (en) * | 2015-12-30 | 2016-04-06 | 中国医学科学院生物医学工程研究所 | Double-wavelength multi-channel laser acupuncture and moxibustion instrument |
| CN110811631A (en) * | 2019-11-07 | 2020-02-21 | 重庆市江津区中心医院 | Pain measuring instrument device for anesthesia department |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101360460A (en) * | 2006-01-20 | 2009-02-04 | 住友电气工业株式会社 | Imaging system |
| CN101569778A (en) * | 2009-03-10 | 2009-11-04 | 深圳先进技术研究院 | Biofeedback simulation system and biofeedback simulation method |
| US20110282334A1 (en) * | 2010-05-11 | 2011-11-17 | Ceramoptec Industries Inc. | Device and method for fistula treatment |
| US20110295344A1 (en) * | 2010-05-28 | 2011-12-01 | Lockheed Martin Corporation | Optical bundle apparatus and method for optical and/or electrical nerve stimulation of peripheral nerves |
| CN203677059U (en) * | 2013-11-21 | 2014-07-02 | 中国医学科学院生物医学工程研究所 | Algesia stimulator |
-
2013
- 2013-11-21 CN CN201310593485.5A patent/CN103584839B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101360460A (en) * | 2006-01-20 | 2009-02-04 | 住友电气工业株式会社 | Imaging system |
| CN101569778A (en) * | 2009-03-10 | 2009-11-04 | 深圳先进技术研究院 | Biofeedback simulation system and biofeedback simulation method |
| US20110282334A1 (en) * | 2010-05-11 | 2011-11-17 | Ceramoptec Industries Inc. | Device and method for fistula treatment |
| US20110295344A1 (en) * | 2010-05-28 | 2011-12-01 | Lockheed Martin Corporation | Optical bundle apparatus and method for optical and/or electrical nerve stimulation of peripheral nerves |
| CN203677059U (en) * | 2013-11-21 | 2014-07-02 | 中国医学科学院生物医学工程研究所 | Algesia stimulator |
Non-Patent Citations (1)
| Title |
|---|
| 李裕昌 等: "1.06μm激光致皮肤痛觉效应的研究", 《激光生物学报》, vol. 19, no. 1, 28 February 2010 (2010-02-28) * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105456024A (en) * | 2015-12-30 | 2016-04-06 | 中国医学科学院生物医学工程研究所 | Double-wavelength multi-channel laser acupuncture and moxibustion instrument |
| CN110811631A (en) * | 2019-11-07 | 2020-02-21 | 重庆市江津区中心医院 | Pain measuring instrument device for anesthesia department |
| CN110811631B (en) * | 2019-11-07 | 2022-07-12 | 重庆市江津区中心医院 | Pain measuring instrument device for anesthesia department |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103584839B (en) | 2015-08-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| King et al. | Effective parameters for ultrasound-induced in vivo neurostimulation | |
| US20170312456A1 (en) | Skin Desensitizing Device | |
| CA2487987C (en) | Method and apparatus for photothermal treatment of tissue at depth | |
| US8029553B2 (en) | Portable laser and process for pain research | |
| US20110172725A1 (en) | Nerve stimulator and method using simultaneous electrical and optical signals | |
| EP1094864B1 (en) | Method and device for stimulating the immune system and generating healing at the cellular level | |
| Zheng et al. | A shape-memory and spiral light-emitting device for precise multisite stimulation of nerve bundles | |
| McCaughey et al. | Novel wavelengths for laser nerve stimulation | |
| CN107427406A (en) | Collagen stimulation apparatus and method | |
| KR20130119795A (en) | Fat removing apparatus using light and ultrasonics wave | |
| CN205569065U (en) | Semiconductor laser therapeutic instrument that moults | |
| CN103584839B (en) | A kind of pain sense stimulation instrument and its implementation | |
| CN203677059U (en) | Algesia stimulator | |
| EP2672913B1 (en) | Laser generator for deep tissue laser treatment using low intensity laser therapy causing selective destruction of nociceptive nerves | |
| RU108309U1 (en) | DEVICE OF LIGHT IMPACT ON A LIVING ORGANISM | |
| KR20140102879A (en) | Electro-acupuncture system | |
| Merrick et al. | A comparison of intramuscular temperatures during ultrasound treatments with coupling gel or gel pads | |
| WO2022158629A1 (en) | Wearable pain treatment device based on principle of complex photobiochemical action | |
| US20220379135A1 (en) | Device for transferring heat and infrared energy, with dynamic temperature control and uniform heat distribution | |
| Clark et al. | Selective, high-optrode-count, artifact-free stimulation with infrared light via intrafascicular utah slanted optrode arrays | |
| CN206549007U (en) | A kind of high-strength focus supersonic therapeutic system | |
| AU2011257952B2 (en) | Method of diagnosis and location of a soft tissue injury | |
| JP2016036429A (en) | Acupuncture point light stimulation device | |
| RU2732706C1 (en) | Improved device for laser therapy | |
| Cayce et al. | Relating optical signals induced by infrared neural stimulation to electrophysiology |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150826 Termination date: 20211121 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |