CN104224128B - A kind of birds visual stimulus monitors and light analysis record system in real time - Google Patents

A kind of birds visual stimulus monitors and light analysis record system in real time Download PDF

Info

Publication number
CN104224128B
CN104224128B CN201410482583.6A CN201410482583A CN104224128B CN 104224128 B CN104224128 B CN 104224128B CN 201410482583 A CN201410482583 A CN 201410482583A CN 104224128 B CN104224128 B CN 104224128B
Authority
CN
China
Prior art keywords
led
resistance
input
circuit
connects
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201410482583.6A
Other languages
Chinese (zh)
Other versions
CN104224128A (en
Inventor
刘苏
肖茜
赵旭东
郭晓菲
王秀春
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Biophysics of CAS
Original Assignee
Institute of Biophysics of CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute of Biophysics of CAS filed Critical Institute of Biophysics of CAS
Priority to CN201410482583.6A priority Critical patent/CN104224128B/en
Publication of CN104224128A publication Critical patent/CN104224128A/en
Application granted granted Critical
Publication of CN104224128B publication Critical patent/CN104224128B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

The present invention relates to a kind of birds visual stimulus monitor in real time and light analysis record service system, it is characterised in that: it includes stereotaxic instrument, recording electrode, eeg amplifier, brain wave acquisition card, computer, optical stimulus signal generator, LED to photo structure, fiber optic tap structure, illumination probe, fluorescence spectrophotometer protractor and six Semi-digital universal meters；It is by converting to light patterns and the simple eye/eyes of intensity Stimulation of Birds, the EEG signals of synchronous recording survey region, and experimenter can utilize this feedback information photic stimuli signal to regulate and control the while of monitoring the illuminance under different condition, wavelength, energy information in real time according to requirement of experiment, these information provide physical parameter support to analyzing EEG signals feature simultaneously.

Description

A kind of birds visual stimulus monitors and light analysis record system in real time
Technical field
The present invention relates to animal brain cognitive techniques field, monitor in real time especially with regard to a kind of birds visual stimulus and light divides New record system.
Background technology
The mankind and most animals depend on vision system to the brightness of object, color, right to the visually-perceptible of exterior object The ratio analysis of the information such as degree, therefore vision system is always scientists primary study object, the vision system that birds are flourishing Unite and be widely adopted in research brain cognitive domain as classical experiment material.
In birds vision system and brain function research, conventional mode is according to the object functionality studied, and designs light Source or image carry out visual stimulus the reaction of synchronous recording related brain areas.Optical signal is by being manually given or calculating The giant-screen that machine controls stimulates.Under the conditions of long time-histories visual stimulus, Artificial Control to light cannot ensure accurate sequential and Time precision and give luminous intensity；Although computer-controlled giant-screen stimulates can guarantee that sequential is accurate, but is not suitable for Under dark room conditions, simple eye/eyes stimulate.
Summary of the invention
For the problems referred to above, it is an object of the invention to provide one and there is programmable type temporal aspect and controllable type luminous intensity Birds visual stimulus monitor in real time and light analysis record system, it is possible to according to requirement of experiment to the illumination under different conditions Degree, wavelength, energy information monitor in real time, it is also possible to adjust visual light stimulus signal according to this feedback information Control.
For achieving the above object, the present invention takes techniques below scheme: a kind of birds visual stimulus real-time monitoring system, It is characterized in that: it include a stereotaxic instrument, a recording electrode, an eeg amplifier, a brain wave acquisition card, one Computer, an optical stimulus signal generator, a LED pop one's head in photo structure, a fiber optic tap structure and an illumination；Bird Class is fixed on described stereotaxic instrument, and the input of described recording electrode is plugged in birds brain district, described recording electrode Output connect the input of described eeg amplifier, the output of described eeg amplifier connects described brain wave acquisition The input of card, the output of described brain wave acquisition card connects described computer；Described optical stimulus signal generator passes through Cable and described LED are connected to excite described LED to send LED light signal, described LED to photo structure to photo structure Connect to photo structure and hold for LED light signal being delivered to described fiber optic tap structure collecting of described fiber optic tap structure Each branch end, one of them branch end alignment birds eyes of described fiber optic tap structure are for transmitting portion LED light Signal is sent to described as light stimulus, light stimulus via the EEG signals that birds produce after described recording electrode collection Eeg amplifier, described eeg amplifier is sent to computer by described eeg signal acquisition card after being amplified by signal and enters Row real time record is analyzed；Part LED light signal is sent to described photograph by another branch end of described fiber optic tap structure Degree probe carries out illuminance detection, and the signal of telecommunication of detection is returned to described light stimulus by cable by described illumination probe to be believed Number generator is for monitoring the brightness value of LED light signal.
When being applicable to eyes pattern, also include a LED and pop one's head in photo structure, a fiber optic tap structure and an illumination； Described optical stimulus signal generator is connected in parallel two described LED to photo structure, and two described LED are to photo structure simultaneously Send the described fiber optic tap structure of LED light signal to two collects end, and each described fiber optic tap structure is wherein One branch end is respectively aligned to two eyes of birds for transmitting portion LED light signal as light stimulus, polished bard regular menstruation during early pregnancy The EEG signals produced by birds are sent to described eeg amplifier by after described recording electrode collection, and described brain is electrically amplified Device is sent to described computer by described brain wave acquisition card after being amplified by signal and carries out real time record analysis；Each institute State another branch end of fiber optic tap structure part LED light signal is sent to corresponding illumination probe respectively to carry out illumination Degree detection, the signal of telecommunication of detection is returned to described optical stimulus signal generator by cable and is used for by illumination probe described in two The brightness value of monitoring LED light signal.
Described optical stimulus signal generator includes a power filtering module, a Switching Power Supply, a timer, a light stimulus Pattern and LED luminance adjust circuit, a left eye LED current display circuit, a right eye LED current display circuit, one Left eye light stimulus illumination circuit, a right eye light stimulus illumination circuit, some switches, some buttons and some connections are used Interface；Wherein, switch includes a photodiode amplifying circuit power switch, a pause switch and a reset switch； Button include a left eye LED luminance adjusting knob, one stimulus modality select knob, a right eye LED luminance adjusting knob, One brain wave acquisition current potential adjusts knob, a LED luminance shelves knob, three left eye light stimulus illumination button and three right eye polished bards Swash illumination button；Connection interface includes a left eye LED cable interface, a right eye LED cable interface, a left eye light Stimulate illumination circuit cable interface, a right eye light stimulus illumination circuit cable interface, a brain wave acquisition card cable interface, One photodiode amplifying circuit cable interface and one or six Semi-digital universal meter cable interfaces；Wherein, described power supply filter The input of mode block connects civil power and is used for being filtered civil power 220V, and the output of described power filtering module is in parallel Connect input and the energization input of described timer of described Switching Power Supply；The output of described Switching Power Supply connects Described light stimulus pattern and LED luminance adjust the input of circuit, and described reset switch and pause switch are respectively with described The input of timer connects, and described timer output end adjusts the letter of circuit with described light stimulus pattern and LED luminance Number input connects；Described light stimulus pattern and LED luminance adjust the input of circuit and are also associated with some knobs, use In the parameter changed in light stimulus pattern and LED luminance adjustment circuit, wherein, described left eye LED luminance adjusting knob It is used for changing to LED loop current value in photo structure, described right eye LED luminance adjusting knob for changing left eye LED Right eye LED to LED loop current value in photo structure, described stimulus modality select knob be used for changing right and left eyes LED to LED stimulus modality in photo structure, described brain wave acquisition current potential adjusts knob and is used for adjusting brain electricity sync signal level amplitude, Described LED luminance shelves knob is for changing LED to the brightness range of LED in photo structure, described light stimulus pattern and LED The output of brightness regulating circuit is connected in parallel the power switch of photodiode amplifying circuit, left eye LED current shows Circuit, right eye LED current display circuit, left eye LED cable interface, right eye LED cable interface, brain wave acquisition card Cable interface, photodiode amplifying circuit cable interface and six Semi-digital universal meter cable interfaces；Wherein, described The power switch of photodiode amplifying circuit is used for controlling photodiode amplifying circuit on/off；Described left eye LED current display circuit is used for showing that left eye LED is to LED loop current value in photo structure, described right eye LED current Display circuit is used for showing that right eye LED is used for LED loop current value in photo structure, described left eye LED cable interface Connecting left eye LED to photo structure, described right eye LED cable interface is used for connecting right eye LED to photo structure, described brain Electricity capture card cable interface is used for connecting described brain wave acquisition card brain electricity synchronizing signal is bright from light stimulus pattern and LED Degree adjusts circuit and sends into described brain wave acquisition card；Described photodiode amplifying circuit cable interface is used for connecting photoelectricity two The signal of telecommunication of conversion is also sent to described six Semi-digital universal meter cable interfaces by pole pipe amplifying circuit, and described six and half Digital multimeter cable interface is for connecting six Semi-digital universal meters；Described left eye light stimulus illumination circuit and left eye light Illumination circuit cable interface is stimulated to be connected for connecting left eye illumination probe and the left eye illumination probe signal of telecommunication being sent to institute State left eye light stimulus illumination circuit；Described right eye light stimulus illumination circuit connects with described right eye light stimulus illumination circuit cable Mouth is connected for connecting right eye illumination probe and the right eye illumination probe signal of telecommunication being sent to described right eye light stimulus illumination electricity Road；Described left eye light stimulus illumination button is connected for changing described left eye polished bard with described left eye light stimulus illumination circuit Swashing illumination circuit parameter, described right eye light stimulus illumination button is connected for changing with described right eye light stimulus illumination circuit Right eye light stimulus illumination circuit parameter.
Described light stimulus pattern and LED luminance adjust circuit and include level shifter interface circuit, sequential logical circuit, many Road gating circuit, left/right eye LED precision standard source constant-current drive circuit, LED chip, brain wave acquisition card signal synchronize Interface circuit, power supply and filter circuit；Described level shifter interface circuit is for the clock pulses letter exported by timer Number CP is converted to be applicable to CMOS level and the signal of Transistor-Transistor Logic level chip operation and produce positive and negative CP clock signal send out Deliver to described sequential logical circuit；Described sequential logical circuit is for receiving what described level shifter interface processing of circuit was crossed Clock signal required for clock signal generation is sent to described multi-strobe circuit；Described multi-strobe circuit will touch Feeding of signaling described left/right eye LED precision standard source constant-current drive circuit, as triggering signal, is used for realizing LED The selection of chip stimulus modality；Described brain wave acquisition card signal synchronous interface circuit is connected use with described multi-strobe circuit In producing the signal of telecommunication Tong Bus with light stimulus, and using the signal of telecommunication described brain wave acquisition card of feeding of light stimulus synchronization as with The reference signal that EEG signals synchronize；Described power supply and filter circuit are used for powering for all circuit chips, and to chip Power supply and ground provide decoupling capacitor filtering.
Described level shifter interface circuit by connector J1, triode Q1, triode Q7, earth resistance R5 and R24, Current-limiting resistance R3 and R23, resistance R22, resistance R6, phase inverter U6A, reverser U6B and reverser U6C composition； Described resistance R3 one end connects the output of described plug-in unit J1, and the described resistance R3 other end connects described triode Q1 Base stage；Described resistance R5 one end connects the base stage of described triode Q1, the other end ground connection of described resistance R5；Institute State the emitter stage that resistance R6 one end connects described triode Q1, the other end ground connection of described resistance R6；Described resistance One end of R23 connects the emitter stage of described triode Q1, and the other end of described resistance R23 connects described triode Q7 Base stage；One end of described resistance R24 connects the base stage of described triode Q7, the other end ground connection of described resistance R24； One end of described resistance R22 connects the colelctor electrode of described triode Q7, another termination 5V power supply of described resistance R22； The input of described phase inverter U6A connects the colelctor electrode of described triode Q7；The input of described phase inverter U6B connects The input of described phase inverter U6A, the output of described phase inverter U6B connects the input of described phase inverter U6C.
Described sequential logical circuit is by JK flip-flop U4A, JK flip-flop U4B, resistance R12, resistance R13, button Switch SV2, resistance R17, resistance R18, key switch SV3, four inputs and door U2A, U2B, U2C and U2D； The output of described phase inverter U6A is connected in parallel described JK flip-flop U4A'sJK flip-flop U4B's Input the input 2B of the input 1A with door U2A and input and door U2B；The K input of described JK flip-flop U4A End, J input and VCC power end connect 5V power supply；One end of described resistance R12 connects 5V power supply, described electricity The other end of resistance R12 connects described JK flip-flop U4A'sOne end of described resistance R13 connects 5V power supply, The other end connects described JK flip-flop U4A'sThe GND ground connection of described JK flip-flop U4A, described JK touches The Q output sending out device U4A is connected with the input 1B of door U2A with described input, described JK flip-flop U4A'sDefeated Go out end to be connected with the input 2A of door U2B with described input；One end of described key switch SV2 connects described JK and touches Send out device U4A'sThe other end ground connection of described key switch SV2；The J input of described JK flip-flop U4B, K input and VCC power end connect 5V power supply；One end of described resistance R17 connects 5V power supply, described resistance R17 The other end connect described JK flip-flop U4BOne end of described resistance R18 connects 5V power supply, the other end Connect trigger U4B described in JKOne end of described key switch SV3 connects described JK flip-flop U4B'sThe other end ground connection of described key switch SV3；The Q output of described JK flip-flop U4B connects described input With the input 4A of door U2D, described JK flip-flop U4B'sOutput connects the input of described input and door U2C End 3A.
Described multi-strobe circuit is made up of two-way eight bit switch SW1, first input of described two-way eight bit switch SW1 End is connected with the 1Y output of door U2A with described input；Second input is unsettled；3rd input and described input with The 1Y output of door U2A connects；Four-input terminal is connected with the output of described phase inverter U6A；5th input with Described input is connected with the output of door U2D；6th input and described JK flip-flop U4B /Q output is connected； 7th input is connected with the Q output of described JK flip-flop U4A；8th input and described input and door U2B Output connect；9th input is unsettled；Tenth input is connected with the output of described input with door U2B；The 11 inputs are connected with the output of described input with door U2B；12nd input is defeated with described phase inverter U6A's Go out end to connect；13rd input is connected with the Q output of described JK flip-flop U4B；Tenth four-input terminal is with described Input is connected with the output of door U2C；15th input is connected with the output of described input with door U2A；Tenth Six inputs and described JK flip-flop U4A /Q output is connected；17th output and described LED precision standard The input 1B of one end of resistance R20 of source constant-current drive circuit, input or door U3A connects；18th output with One end of the resistance R11 of described LED precision standard source constant-current drive circuit, input are connected with the input 1A of door U3A.
Described LED precision standard source constant-current drive circuit include voltage-reference U1, voltage-reference U5, resistance R1, Resistance R2, resistance R10, resistance R11, resistance R14, resistance R15, resistance R16, resistance R19, resistance R20, Resistance R21, resistance R25, resistance R26, triode Q3, triode Q4, triode Q5, triode Q6, LED To LED chip D2 in photo structure, LED to LED chip D3 in photo structure, LED luminance adjusting knob W1, LED luminance adjusting knob W3, LED current display circuit J3, LED current display circuit J4 and two-way two-position switch SW4； The other end of described resistance R11 connects the base stage of described triode Q4；One end of described resistance R14 connects described three poles The base stage of pipe Q4, other end ground connection；The grounded emitter of described triode Q4；The colelctor electrode of described triode Q4 is also Connection connects described resistance R2 and one end of resistance R10, the other end of described resistance R2 and described voltage-reference U1 Negative electrode connect, the other end of described resistance R10 is connected with the anode of described voltage-reference U1, described voltage reference The negative electrode of source U1 is connected in parallel 12V power supply, resistance R1 and one end of resistance R25；The other end of described resistance R1 with One group of normally opened contact of described two-way two-position switch SW4 connects, the other end of described resistance R25 and described two-way two One group of normally-closed contact of switch SW4 connects, one group of common port of described two-way two-position switch SW4 and described LED luminance The sliding end of adjusting knob W1 connects, and the fixing end of described LED luminance adjusting knob W1 is sent out with described triode Q3's Emitter-base bandgap grading connects, and the base stage of described triode Q3 is connected with the anode of described voltage-reference U1, described triode Q3 Colelctor electrode be connected to the anode of LED chip D2 in photo structure with described LED, described LED is in photo structure The negative electrode of LED chip D2 is connected with the signal input part of LED current display circuit J3, described LED current display electricity The signal ground of road J3 and power supply ground ground connection, power supply connects 5V power supply.One end of described resistance R20 and described triode Q6 Base stage, resistance R21 one end connect, the other end ground connection of described resistance R21, described triode Q6 emitter stage connects Ground.The colelctor electrode of described triode Q6 is connected with one end of resistance R16, one end of resistance R19, described resistance R16 The other end be connected with the negative electrode of described voltage-reference U5, the other end of described resistance R19 and described voltage-reference The anode of U5 connects, the negative electrode of described voltage-reference U5 and 12V power supply, one end of resistance R15, resistance R26 One end connect；Another group normally opened contact of the other end of described resistance R26 and described two-way two-position switch SW4 is connected, The other end of resistance R15 is connected with another group normally-closed contact of two-way two-position switch SW4, described two-way two-position switch SW4 Another group common port be connected with the sliding end of described LED luminance adjusting knob W3, LED luminance adjusting knob W3's Fixing end is connected with the emitter stage of triode Q5, the base stage of described triode Q5 and the anode of described voltage-reference U5 Connecting, the colelctor electrode of described triode Q5 is connected to the anode of LED chip D3 in photo structure with described LED, institute State LED to connect to the signal ground of the negative electrode of LED chip D3 in photo structure and LED current display circuit J4 and power supply Ground, power supply connects 5V power supply.
Described LED includes magnet base cross rod frame, LED support bar, LED support rod connecting sleeve, two core electricity to photo structure Cable plug female, two core cable plug male plug, LED and aluminium base and LED lamp cover；Described magnet base crossbar The top of frame arranges a rectangle metal derby with two mutually orthogonal circular holes, and described LED support bar passes rectangle The orthogonal hole of metal derby is fastened by bolt lock with described magnet base cross rod frame；One end set of described LED support bar Being provided with described LED support rod connecting sleeve, the outer end of described LED support rod connecting sleeve is threaded connection described two core electricity Cable plug male, described two core cable plug male connects described two core cable plug female, described LED by contact pin The other end of support bar is threaded connection described LED and aluminium base, and the outside of described LED and aluminium base is sheathed described LED lamp cover, described LED positive pole connects a two core cable wherein cable, and LED negative pole connects another in two core cable Root cable.
A kind of birds visual stimulus light analysis record system, it is characterised in that: it includes a stereotaxic instrument, a polished bard Energizing signal generator, a LED to photo structure, an optical fiber structure, a fiber optic tap structure, a light intensity test module, One sepectrophotofluorometer and a computer；Birds are fixed on described stereotaxic instrument, and described optical stimulus signal occurs Device is connected to excite LED to send LED light signal, described LED to photo structure to photo structure with described LED by cable The input of described optical fiber structure is connected, a wherein eye of the output alignment birds of described optical fiber structure to photo structure Eyeball is used for sending LED light signal and the LED light signal of decay is sent out as light stimulus, the eye socket of the another eyes of birds That delivers to described fiber optic tap structure collects end, collects end and the LED light signal of decay from birds eye socket is passed to respectively Branch end, the part LED light signal of reception is sent to described light by one of them branch end of described fiber optic tap structure Testing by force module, the optical signal received is converted to voltage signal and is sent to described light stimulus by described light intensity test module Signal generator；The part LED light signal of reception is sent to institute by another fiber optic tap end of described fiber optic tap structure Stating sepectrophotofluorometer, described sepectrophotofluorometer carries out spectral scan to the LED light signal received, and by light Spectrum scanning result is sent to described computer and is analyzed.
Also include that one for the fiber optic tap arrangement holding device being supported described fiber optic tap structure, it includes magnetic Power seat cross rod frame, photodiode amplifying circuit contact pin line sheath, photodiode amplifying circuit, optical fiber and light Electric diode amplifying circuit adapter sleeve, two branch optical fibers, bleeding-stopping dressing, two branch optical fiber grooves hold blocks and three-dimensional shifting Moving platform bridge；The top of described magnet base cross rod frame arranges a rectangle metal with two mutually orthogonal circular holes Block, one end of described photodiode amplifying circuit contact pin line sheath is through described rectangle metal derby circular hole and passes through Bolt is locked with described magnet base cross rod frame, another of described photodiode amplifying circuit contact pin line sheath End connects described photodiode amplifying circuit, and described photodiode amplifying circuit is by described optical fiber and photoelectricity two pole Pipe amplifying circuit adapter sleeve connects a wherein branch end of described two branch optical fibers, another branch of described two branch optical fibers Optical fiber connects described sepectrophotofluorometer, and the end that collects of described two branch optical fibers fixes connection bleeding-stopping dressing；Described two The end that collects of branch optical fiber supports fixing by described two branch optical fiber grooves hold blocks, described two branch optical fiber groove folders Hold block fixed placement on described three-dimensional mobile platform bridge.
Due to the fact that and take above technical scheme, it has the advantage that 1, optical stimulus signal generator in the present invention Eight kinds of stimulus modalities can be provided, and the CP clock signal that can arrange multiple time span is stung for the circulation of pattern Swash, it is possible to according to requirement of experiment, the illuminance under different conditions, wavelength, energy information are monitored in real time, it is possible to Visual light stimulus signal is regulated and controled according to this feedback information.2, the present invention utilizes two-way eight bit switch to realize stimulating Pattern switching has minimum wiring and stable duty compared with the method such as analog switch and multi channel selecting.3, originally The LED precision standard source constant-current drive circuit of invention rather than PWM light adjusting circuit, on the one hand can as brightness adjustment mode To provide the constant current that stability is higher, on the other hand constant luminance is more suitable for visual experiment.4, the electricity of the present invention Stream display circuit may indicate that current by LED current value, supports for later data analysis.5, the illumination of the present invention Circuit can receive the signal of telecommunication of illumination probe feedback, shows LED illuminance in real time, and this feedback system is for realizing illumination Light stimulus accurately provides and ensures.6, the brain wave acquisition card signal synchronous interface circuit of the present invention is connected with brain wave acquisition card, Software extensions can be analyzed with other to use.7, the LED of the present invention to LED chip distribution curve flux level in photo structure and hangs down Nogata, to identical, reassemble 30 degree of corner lamp covers of frosting and ensure that emergent ray enters all directions uniformity of optical fiber.8、 The light of equal portions is given animal used as test and feedback illumination probe by the two branch optical fiber approximations of the present invention respectively, projects with optical fiber Evenly, the use of rubber optical fiber cover is not only possible to prevent light leakage but also can realize connecing with animal used as test softness the light gone out Touch；Optical fiber and illumination probe adjust frame and can ensure that two branch optical fiber light path shape approximately equals, and optical signal is by shining Degree probe circuit form feeds back illumination intensity signal, reduces optical path distance, reduces the mistake formed due to attenuation as far as possible Difference.9, due to the fact that employing bleeding-stopping dressing, be therefore easy to absorptive tissue liquid.10, the present invention is provided with fluorescence and divides Light photometer, the spectral results utilizing high sensitivity sepectrophotofluorometer scanning optical fiber to import light gained is better than existing skill The equipment acquired results of the measure spectrum in art.The present invention can be widely applied to birds visual stimulus and monitors in real time and light During analysis.
Accompanying drawing explanation
Fig. 1 is birds visual stimulus real-time monitoring system schematic diagram of the present invention；
Fig. 2 is birds visual stimulus light analysis record system schematic of the present invention；
Fig. 3 is light stimulus pattern and the LED luminance adjustment circuitry block schematic diagram of the present invention；
Fig. 4 is light stimulus pattern and the LED luminance adjustment circuit theory diagrams of the present invention, and Fig. 4 (a) is that level conversion connects Mouth circuit theory schematic diagram, Fig. 4 (b) is sequential logical circuit principle schematic, and Fig. 4 (c) is multi-strobe circuit Principle schematic, Fig. 4 (d) is LED precision standard source constant-current drive circuit principle schematic, and Fig. 4 (e) is brain electricity Capture card signal synchronous interface circuit principle schematic；
Fig. 5 is 8 kinds of light stimulus mode signal schematic diagrames of the present invention；
Fig. 6 is that the LED of the present invention is to photo structure schematic diagram；
Fig. 7 is the fiber optic tap arrangement holding device structural representation of the present invention；
Fig. 8 is another fiber optic tap arrangement holding device structural representation of the present invention.
Detailed description of the invention
With embodiment, the present invention is described in detail below in conjunction with the accompanying drawings.
As it is shown in figure 1, the birds visual stimulus real-time monitoring system of the present invention includes stereotaxic instrument 11, record Electrode 12, one eeg amplifier 13, brain wave acquisition card 14, computer 15, optical stimulus signal generator 16, One LED is to photo structure 17, fiber optic tap structure 18 and illumination probe 19；Experiment birds are fixed on stereoscopic localized On instrument 11, the input of recording electrode 12 is plugged in birds brain district, and it is electrically amplified that the output of recording electrode 12 connects brain The input of device 13, the output of eeg amplifier 13 connects the input of brain wave acquisition card 14, brain wave acquisition card The output of 14 connects computer 15；Optical stimulus signal generator 16 is connected use with LED to photo structure 17 by cable In exciting LED to send LED light signal to photo structure 17, LED connects the remittance of fiber optic tap structure 18 to photo structure 17 Total end for being delivered to each branch end of fiber optic tap structure 18 by LED light signal, and fiber optic tap structure 18 is wherein One branch end alignment birds eye produces via birds as light stimulus, light stimulus for transmitting portion LED light signal EEG signals be recorded electrode 12 gather after be sent to eeg amplifier 13, eeg amplifier 13 by signal amplify after It is sent to computer 15 by eeg signal acquisition card 14 and carries out real time record analysis；Another of fiber optic tap structure 18 Part LED light signal is sent to illumination probe 19 and carries out illuminance detection by individual branch end, and illumination probe 19 will detection The signal of telecommunication be returned to optical stimulus signal generator 16 for monitoring the brightness value of LED light signal by cable.
The birds visual stimulus real-time monitoring system of the present invention goes for simple eye pattern (birds left eye or right eye), also Go for eyes pattern (birds eyes), when the present invention is applicable to eyes pattern, also include that a LED ties to light Structure, a fiber optic tap structure and illumination probe；Optical stimulus signal generator 16 is connected in parallel two LED to photo structure 17, two LED send LED light signal simultaneously and collect end, often to two fiber optic tap structures 18 to photo structure 17 One of them branch end of one fiber optic tap structure is respectively aligned to two eyes of birds and believes for transmitting portion LED light Number as light stimulus, light stimulus is recorded via the EEG signals that birds produce that to be sent to brain after electrode 12 gathers electrically amplified Device 13, eeg amplifier 13 is sent to computer 15 by brain wave acquisition card 14 after being amplified by signal and remembers in real time Record is analyzed；Part LED light signal is sent to corresponding illumination by another branch end of each fiber optic tap structure respectively Probe carries out illuminance detection, and the signal of telecommunication of detection is returned to optical stimulus signal by cable and occurs by two illumination probes 19 Device 16 is for monitoring the brightness value of LED light signal.
As in figure 2 it is shown, the birds visual stimulus light analysis record system of the present invention is suitable only for simple eye pattern, including One stereotaxic instrument 21, optical stimulus signal generator 22, LED is to photo structure 23, optical fiber structure 24, Fiber optic tap structure 25, one light intensity test module 26, sepectrophotofluorometer 27 and a computer 28；Experiment bird Class is fixed on stereotaxic instrument 21, and optical stimulus signal generator 22 is connected use with LED to photo structure 23 by cable In exciting LED to send LED light signal to photo structure, LED connects the input of optical fiber structure 24 to photo structure 23, A wherein eye (these eyes are intact) of the output alignment birds of optical fiber structure 24 is used for sending LED light letter Number as light stimulus, the eye socket of the another eyes (this eyeball has been extractd) of birds will the LED light letter of decay Number be sent to fiber optic tap structure 25 collects end, collects to hold and the LED light signal of decay from birds eye socket is passed to Each branch end, the part LED light signal of reception is sent to light intensity and surveys by one of them branch end of fiber optic tap structure 25 Die trial block 26, the light intensity signal received is converted to voltage signal and is sent to optical stimulus signal by light intensity test module 26 Generator 22；The part LED light signal of reception is sent to fluorescence by another fiber optic tap end of fiber optic tap structure 25 Spectrophotometer 27, sepectrophotofluorometer 27 carries out spectral scan to the LED light signal received, and is swept by spectrum Retouch result to be sent to computer 28 and be analyzed.When birds eye socket decay light is more weak (when eye-observation is insensitive), Light intensity test module 26 can use photodiode amplifying circuit, the light intensity that photodiode amplifying circuit will receive Signal is converted to voltage signal and is sent to optical stimulus signal generator 22, and optical stimulus signal generator 22 is by voltage signal Being sent to six Semi-digital universal meters, six Semi-digital universal meters are for showing the magnitude of voltage of avian tissue decay optical signal. When birds eye socket decay light is stronger, light intensity test module 26 can also use illumination to pop one's head in, and illumination probe will receive Light intensity signal be converted to voltage signal and be sent to optical stimulus signal generator 22 and show avian tissue decay optical signal Brightness value.
In above-described embodiment, optical stimulus signal generator include a power filtering module, a Switching Power Supply, a timer, One light stimulus pattern and LED luminance adjust circuit, a left eye LED current display circuit, a right eye LED current show If circuit, a left eye light stimulus illumination circuit, a right eye light stimulus illumination circuit, some switches, some buttons and Involvement connects uses interface；Wherein, switch includes that a photodiode amplifying circuit power switch, a pause switch and one are multiple Bit switch；Button includes that a left eye LED luminance adjusting knob, a stimulus modality select knob, a right eye LED luminance Adjusting knob, one brain wave acquisition current potential adjust knob, a LED luminance shelves knob, three left eye light stimulus illumination buttons and Three right eye light stimulus illumination buttons；Connection interface include a left eye LED cable interface, a right eye LED cable interface, One left eye light stimulus illumination circuit cable interface, a right eye light stimulus illumination circuit cable interface, a brain wave acquisition card electricity Cable interface, a photodiode amplifying circuit cable interface and one or six Semi-digital universal meter cable interfaces.
Wherein, the input of power filtering module connects civil power and is used for being filtered civil power 220V, power filtering module Output be connected in parallel the input of Switching Power Supply and the energization input of timer, for Switching Power Supply and timing Device provides electric power.The output connection light stimulus pattern of Switching Power Supply and the input of LED luminance adjustment circuit are used for Light stimulus pattern and LED luminance adjust circuit and provide electric power.Reset switch and pause switch respectively with the input of timer End connects, and resets for control timer and suspends；Timer output end adjusts electricity with light stimulus pattern and LED luminance The signal input part on road connects, and provides clock pulses for adjusting circuit for LED luminance.
Light stimulus pattern and LED luminance adjust the input of circuit and are also associated with some knobs, are used for changing light stimulus mould Formula and LED luminance adjust the parameter in circuit, and wherein, left eye LED luminance adjusting knob (potentiometer) is used for changing Left eye LED is to LED loop current value in photo structure；Right eye LED luminance adjusting knob (potentiometer) is used for changing the right side Eye LED is to LED loop current value in photo structure；Stimulus modality selects knob to be used for changing right and left eyes LED to photo structure Middle LED stimulus modality；Brain wave acquisition current potential adjusts knob and is used for adjusting brain electricity sync signal level amplitude；LED luminance Shelves knob is for changing LED to the brightness range of LED in photo structure.Light stimulus pattern and LED luminance adjust circuit Output is connected in parallel the power switch of photodiode amplifying circuit, left eye LED current display circuit, right eye LED Current display circuit, left eye LED cable interface, right eye LED cable interface, brain wave acquisition card cable interface, photoelectricity Diode amplifying circuit cable interface and six Semi-digital universal meter cable interfaces；Wherein, photodiode amplifying circuit Power switch be used for controlling photodiode amplifying circuit on/off；Left eye LED current display circuit is used for showing Left eye LED is to LED loop current value in photo structure；Right eye LED current display circuit is used for showing that right eye LED is to light LED loop current value in structure；Left eye LED cable interface is used for connecting left eye LED to photo structure；Right eye LED electricity Cable interface is used for connecting right eye LED to photo structure；Brain wave acquisition card cable interface is used for connecting brain wave acquisition card and by brain Electricity synchronizing signal adjusts circuit from light stimulus pattern and LED luminance and sends into brain wave acquisition card；Photodiode amplifying circuit Cable interface is for connecting photodiode amplifying circuit and the signal of telecommunication of conversion being sent to six Semi-digital universal meter electricity Cable interface, six Semi-digital universal meter cable interfaces are for connecting six Semi-digital universal meters, six Semi-digital universal meters The signal of telecommunication is sent to six Semi-digital universal meters by cable interface again.
Left eye light stimulus illumination circuit is connected with left eye light stimulus illumination circuit cable interface for being connected left eye illumination probe And the left eye illumination probe signal of telecommunication is sent to left eye light stimulus illumination circuit；Right eye light stimulus illumination circuit and right eye light Illumination circuit cable interface is stimulated to be connected for connecting right eye illumination probe and the right eye illumination probe signal of telecommunication being sent to the right side Eye stimulates illumination circuit.Left eye light stimulus illumination button is connected for changing left eye light with left eye light stimulus illumination circuit Stimulating illumination circuit parameter, right eye light stimulus illumination button is connected for changing right eye light with right eye light stimulus illumination circuit Stimulate illumination circuit parameter.
In the various embodiments described above, as it is shown on figure 3, light stimulus pattern and LED luminance adjust circuit includes that level conversion connects Mouth circuit 31, sequential logical circuit 32, multi-strobe circuit 33, the constant current of left/right eye LED precision standard source drive electricity Road 34, brain wave acquisition card signal synchronous interface circuit 35, LED chip 36, power supply and filter circuit 37.
Wherein, as shown in Fig. 4 (a), level shifter interface circuit 31 is for the clock pulses letter exported by timer Number CP is converted to be applicable to CMOS level and the signal of Transistor-Transistor Logic level chip operation and produce positive and negative CP clock signal send out Delivering to sequential logical circuit, level shifter interface circuit also includes for eliminating the small mistake that may cause in clock signal The anti-clutter circuit of actuating signal.Wherein, level shifter interface circuit is by connector J1, triode Q1, triode Q7, earth resistance (resistance R5 and resistance R24), current-limiting resistance (resistance R3 and resistance R23), resistance R22, electricity Resistance R6, phase inverter U6A, reverser U6B and reverser U6C composition.Resistance R3 one end connects the defeated of connector J1 Go out end, the base stage of resistance R3 other end connecting triode Q1；The base stage of resistance R5 one end connecting triode Q1, electricity The other end ground connection of resistance R5；The emitter stage of resistance R6 one end connecting triode Q1, the other end ground connection of resistance R6； The emitter stage of one end connecting triode Q1 of resistance R23, the base stage of the other end connecting triode Q7 of resistance R23； The base stage of one end connecting triode Q7 of resistance R24, the other end ground connection of resistance R24；One end of resistance R22 connects The colelctor electrode of triode Q7, another termination 5V power supply of resistance R22；The input connecting triode of phase inverter U6A The colelctor electrode of Q7；The input of phase inverter U6B connects the input of phase inverter U6A, and the output of phase inverter U6B is even The input meeting phase inverter U6C connects.The output of phase inverter U6C and the 3B input inputted with door U2C and input It is connected with the 4B input of door U2D.Wherein, resistance R3, resistance R5, resistance R6 and triode Q1 composition are followed The 2v high level CP that timer is exported by device transfers Transistor-Transistor Logic level to；Triode Q7 and resistance R22, resistance R23 and electricity Resistance R24 composition phase inverter is used for improving output loading capability；Signal through level translation becomes CP and warp by U6A Crossing phase inverter U6B and phase inverter U6C, signal becomes/CP, phase inverter U6 and is mainly responsible for the shaping of CP square wave, removes The concussion on rise and fall edge.In foregoing circuit, resistance R5 and resistance R24 is not having high potential through triode Q1 During with the base stage of triode Q7, transistor base is embedded in earth potential, prevents triode due to interference signal misoperation.
As shown in Fig. 4 (b), the clock letter that sequential logical circuit 32 is crossed for receiving level shifter interface processing of circuit Number and produce required for clock signal, sequential logical circuit produce impulse waveform be sent to multi-strobe circuit.Time Sequence logic circuit is by JK flip-flop U4A, JK flip-flop U4B, resistance R12, resistance R13, key switch SV2, electricity Resistance R17, resistance R18, key switch SV3, four inputs and door (U2A, U2B, U2C and U2D)；Phase inverter U6A Output be connected in parallel JK flip-flop U4A'sJK flip-flop U4B'sInput is defeated with door U2A's Enter to hold the input 2B of 1A and input and door U2B；The K input of JK flip-flop U4A, J input and VCC electricity Source connects 5V power supply；One end of resistance R12 connects 5V power supply, and the other end of resistance R12 connects JK flip-flop U4A'sOne end of resistance R13 connects 5V power supply, and the other end connects JK flip-flop U4A'sJK touches Sending out the GND ground connection of device U4A, the Q output of JK flip-flop U4A is connected with the input 1B of door U2A with input, JK flip-flop U4A'sOutput is connected with the input 2A of door U2B with input；One end of key switch SV2 is even Connect JK flip-flop U4A'sThe other end ground connection of key switch SV2；The J input of JK flip-flop U4B, K Input) and VCC power end connection 5V power supply；One end of resistance R17 connects 5V power supply, another of resistance R17 End connects JK flip-flop U4B'sOne end of resistance R18 connects 5V power supply, and the other end connects JK flip-flop U4B'sOne end of key switch SV3 connects JK flip-flop U4B'sAnother of key switch SV3 End ground connection；The Q output of JK flip-flop U4B connects the input 4A of input and door U2D, JK flip-flop U4B's Output connects the input 3A of input and door U2C.
In foregoing circuit, JK flip-flop U4A and JK flip-flop U4B constitutes d type flip flop, resistance R12, resistance R13, resistance R17, resistance R18, key switch SV2, key switch SV3 determine the duty of circuit.Warp Cross JK flip-flop U4 generate fractional frequency signal Q1 ,/Q1, Q2 ,/Q2 carry out with CP signal again with computing obtain A, B, Tetra-groups of signals of C, D, these eight groups of signals combine into eight kinds of stimulus modalities.Sequential logical circuit utilizes JK flip-flop U4 Do and computing with CP next time after making this signal Q generated or/Q stably along triggering feature after chip, this reality Existing mode has evaded the sequential logic confusion likely caused because of the race and hazard phenomenon in circuit cleverly, adds Signal reliability.As it is shown in figure 5, the mode of operation under LED light stimulates includes eight kinds of display patterns:
The first shows pattern: when first CP high level, left eye LED lights, first CP low level and second Individual CP left eye LED extinguishes, and right eye LED extinguishes all the time, circulates successively.
The second display pattern: during first CP high level, right eye LED lights, first CP low level and second During individual CP, right eye LED extinguishes, and left eye LED extinguishes all the time, circulates successively.
The third shows pattern: when first Clock pulse CP is high level, left eye LED lights, now right eye LED extinguishes, and when first CP is low level, two LED extinguish.The right eye LED when second CP high level Lighting, left eye LED extinguishes, and when second CP low level, eyes LED extinguishes, and circulates successively.
4th kind of display pattern: eyes LED lights simultaneously when CP high level, and eyes LED is when CP low level Extinguish, circulate successively.
5th kind of display pattern: first CP left eye LED lights, and right eye LED lights low at first CP high level Level extinguishes, and all extinguishes at second CP eyes LED, circulates successively.
6th kind of display pattern: first CP right eye LED lights, and left eye LED lights low at first CP high level Level extinguishes, and all extinguishes at second CP eyes LED, circulates successively.
7th kind of display pattern: first CP left eye LED lights, and right eye LED extinguishes low at first CP high level Level is lighted, and all extinguishes at second CP eyes LED, circulates successively.
8th kind of display pattern: first CP right eye LED lights, and left eye LED extinguishes low at first CP high level Level is lighted, and all extinguishes at second CP eyes LED, circulates successively.
As shown in Fig. 4 (c), two-way eight bit switch SW1 is for realizing the selection of stimulus modality, and is sent out by triggering signal Deliver to LED precision standard source constant-current drive circuit as trigger signal, multi-strobe circuit 33 is by two-way eight bit switch SW1 forms, and the first input end 1 of two-way eight bit switch SW1 is connected with the 1Y output of door U2A with input；Two-way Second input 2 of eight bit switch SW1 is unsettled, the 3rd input 3 of two-way eight bit switch SW1 and input and door U2A 1Y output connect；The four-input terminal 4 of two-way eight bit switch SW1 is connected with the output of phase inverter U6A；Double 5th input of road eight bit switch SW1 is connected with the output of door U2D with input；The of two-way eight bit switch SW1 Six inputs 6 and JK flip-flop U4B /Q output is connected；7th input 7 of two-way eight bit switch SW1 with The Q output of JK flip-flop U4A connects；8th input 8 of two-way eight bit switch SW1 and input are with door U2B's Output connects；9th input 9 of two-way eight bit switch SW1 is unsettled；Tenth input of two-way eight bit switch SW1 End 10 is connected with the output of door U2B with input；11st input 11 of two-way eight bit switch SW1 and input with The output of door U2B is connected；12nd input 12 of two-way eight bit switch SW1 is with the output of phase inverter U6A even Connect；13rd input 13 of two-way eight bit switch SW1 is connected with the Q output of JK flip-flop U4B；Two-way eight Tenth four-input terminal 14 of bit switch SW1 is connected with the output of door U2C with input；The of two-way eight bit switch SW1 15 inputs 15 are connected with the output of door U2A with input；16th input 16 of two-way eight bit switch SW1 With JK flip-flop U4A /Q output is connected；17th output 17 of two-way eight bit switch SW1 and resistance R20 One end, input or door U3A input 1B connect；18th output 18 and the electricity of two-way eight bit switch SW1 One end of resistance R11, input are connected with the input 1A of door U3A.Multi-strobe circuit has been abandoned and has been utilized multi channel selecting core The traditional design thinking of sheet or analog switch, utilizes wire structures and two-way eight bit switch to realize as transmission signal vector Multi channel selecting.Two groups of terminals of two-way eight bit switch SW1 meet 8 kinds of signals of right and left eyes, two-way eight bit switch SW1 respectively The 17th output the 17 and the 18th output 18 connect right and left eyes LED precision standard source constant-current drive circuit respectively. This kind of design makes PCB layout minimum minimizing circuit complexity, stable and reliable in work at low frequency state, contact resistance Little and model selection can be carried out when instrument no power.
As shown in Fig. 4 (d), LED precision standard source constant-current drive circuit 34 is for the electric current stable for LED offer Input also realizes stepless continuous adjustment to the electric current produced.LED precision standard source constant-current drive circuit includes voltage reference Source U1, voltage-reference U5, resistance R1, resistance R2, resistance R10, resistance R11, resistance R14, resistance R15, Resistance R16, resistance R19, resistance R20, resistance R21, resistance R25, resistance R26, triode Q3, triode Q4, triode Q5, triode Q6, LED to LED chip D2 in photo structure, LED to the LED in photo structure Chip D3, LED luminance adjusting knob W1, LED luminance adjusting knob W3, LED current display circuit J3, LED electricity Stream display circuit J4 and two-way two-position switch SW4.The base stage of the other end connecting triode Q4 of resistance R11；Resistance The base stage of one end connecting triode Q4 of R14, other end ground connection；The grounded emitter of triode Q4；Triode Q4 Colelctor electrode be connected in parallel resistance R2 and one end of resistance R10, the moon of the other end of resistance R2 and voltage-reference U1 Pole connects, and the other end of resistance R10 is connected with the anode of voltage-reference U1, and the negative electrode of voltage-reference U1 is in parallel Connect 12V power supply, resistance R1 and one end of resistance R25；The other end of resistance R1 is with two-way two-position switch SW4's One group of normally opened contact connects, and the other end of resistance R25 is connected with one group of normally-closed contact of two-way two-position switch SW4, double One group of common port of road two-position switch SW4 is connected with the sliding end of LED luminance adjusting knob W1, LED luminance regulation rotation The fixing end of button W1 is connected with the emitter stage of triode Q3, the base stage of triode Q3 and the anode of voltage-reference U1 Connecting, the colelctor electrode of triode Q3 is connected to the anode of LED chip D2 in photo structure with LED, and LED ties to light The negative electrode of LED chip D2 in structure is connected with the signal input part of LED current display circuit J3, and LED current shows The signal ground of circuit J3 and power supply ground ground connection, power supply connects 5V power supply.The base stage of one end of resistance R20 and triode Q6, One end of resistance R21 connects, the other end ground connection of resistance R21, triode Q6 grounded emitter.Triode Q6's Colelctor electrode is connected with one end, one end of resistance R19 of resistance R16, the other end of resistance R16 and voltage-reference U5 Negative electrode connect, the other end of resistance R19 is connected with the anode of voltage-reference U5, the negative electrode of voltage-reference U5 It is connected with 12V power supply, one end of resistance R15, one end of resistance R26.The other end of resistance R26 and two-way two Another group of another group normally opened contact connection, the other end of resistance R15 and the two-way two-position switch SW4 of switch SW4 is often Closed contact connects, and another group common port of two-way two-position switch SW4 is connected with the sliding end of LED luminance adjusting knob W3, The fixing end of LED luminance adjusting knob W3 is connected with the emitter stage of triode Q5, the base stage of triode Q5 and voltage base The anode of quasi-source U5 connects, and the colelctor electrode of triode Q5 is connected to the anode of LED chip D3 in photo structure with LED, LED to the signal ground of the negative electrode of LED chip D3 in photo structure and LED current display circuit J4 and power supply ground ground connection, Power supply connects 5V power supply.
LED precision standard source constant-current drive circuit is described below as a example by the constant-current drive circuit of left eye LED precision standard source Structure, this structure uses darlington structure to promote triode carrying load ability, and triode Q4, triode Q3 make respectively Base stage and emitter stage for Darlington transistor.Resistance R11 and resistance R2 is that triode Q4 sets operating point, resistance R14 Ensure that triode Q4 is when no signal, it is ensured that earth potential.Voltage-reference U1 and resistance R1 (or resistance R25), LED Brightness regulation knob W1, the base stage parallel connection of triode Q3, it is ensured that resistance R1 (or resistance R25), LED luminance regulate Knob W1, the base stage constant voltage of triode Q3, therefore change LED luminance adjusting knob W1 on the basis of voltage is certain Resistance just can change loop current, thus change LED luminance.Voltage-reference U1 be high-precision voltage stabilizing pipe thus Ensure that the stability of electric current.Two-way two-position switch SW4 and resistance R1, resistance R25 composition LED luminance shelves adjust electricity Road, by selecting different resistance to arrange loop base current value in the loop.LED chip is for producing birds eyes Light stimulus, this chip 0～180 degree identical with 90～270 degree of distribution curve fluxs, the most any angle rotate all Make axial direction uniform intensity.
As shown in Fig. 4 (e), brain wave acquisition card signal synchronous interface circuit 35 is connected to multi-strobe circuit 33 Produce the signal of telecommunication Tong Bu with light stimulus, and the signal of telecommunication that light stimulus is synchronized send into brain wave acquisition card as with brain telecommunications Number synchronize reference signal, its circuit can also adjust level output amplitude and match with cmos circuit and TTL circuit. This circuit comprises indicator light circuit, can signal through time light.Brain wave acquisition card signal synchronous interface circuit includes Resistance R7, resistance R8, input or door U3A, resistance R4, resistance R9, signal lamp D1, triode Q2, brain Electricity gathers current potential and adjusts knob W2 and brain wave acquisition card cable interface J2.One end of resistance R7 and input or door U3A's First input end 1A connects, other end ground connection；One end of resistance R8 and input or the second input 1B of door U3A Connect, the other end ground connection of resistance R8.Output 1Y and resistance R4 one end of input or door U3A is connected, resistance The other end of R4 is connected in parallel one end of resistance R9, the base stage of triode Q2 and the anode of signal lamp D1, electricity The other end ground connection of resistance R9, the minus earth of signal lamp D1, the colelctor electrode of triode Q2 connects 5V power supply, One end that the emitter stage of triode Q2 adjusts knob W2 with brain wave acquisition current potential is connected, and brain wave acquisition current potential adjusts knob The sliding end of W2 is connected with brain wave acquisition card cable interface J2, and brain wave acquisition current potential adjusts another fixing end of knob W2 Ground connection.Four input right and left eyes LED drive signal H1, H2 are asked by door U3A or computing be sent to by resistance R4, R9, Knob W2, signal lamp D1 and the follower circuit of triode Q2 composition, adjust by adjusting brain wave acquisition current potential The resistance of knob W2 realizes the change of output voltage, and D1 is signal lamp, when there being stimulus signal to occur, and D1 point Bright.H1 and H2 must be carried out or computing could produce the signal that can distinguish right and left eyes in brain wave acquisition card.
Power supply and filter circuit 37 are for powering for all circuit chips, and provide decoupling capacitor filter to chip power and ground Ripple, provides energy for above-mentioned all modules and removes interference.Power supply and filtration module mainly positive and negative 15V is converted to 12V, 9V, 5V, and be that each chip adds decoupling capacitor elimination power supply and chip chamber interference.12V is that LED precision standard source is permanent Stream drive circuitry, 9V is that light stimulus illumination circuit is powered, and 5V is that all of digit chip is powered.
In the various embodiments described above, as shown in Figure 6, to photo structure, LED includes that magnet base cross rod frame 41, LED support Bar 42, LED support rod connecting sleeve 43, two core cable plug male plug 44, two core cable plug female 45, LED And aluminium base 46 and LED lamp cover 47, the top of magnet base cross rod frame 41 arranges one and has two mutually orthogonal circular holes Rectangle metal derby, LED support bar 42 leads to through the orthogonal hole of rectangle metal derby with magnet base cross rod frame 41 Cross bolt lock to fasten；One end of LED support bar 42 is arranged with LED support rod connecting sleeve 43, and LED support bar connects The outer end of set 43 is threaded connection two core cable plug male 44, and two core cable plug male 44 is connected by contact pin Two core cable plug female 45, the other end of LED support bar 42 is threaded connection LED and aluminium base 46, LED And the sheathed LED lamp cover in outside 47 of aluminium base 46, LED positive pole connects a two core cable wherein cable, and LED bears Pole connects another root cable in two core cable；Wherein, aluminium base is for dispelling the heat to LED, and LED lamp cover 47 uses table Face frosted, the cloche of internal 30 degree of angles, it is therefore an objective to be used for into 30 degree of angle throw lights.
In the various embodiments described above, as it is shown in fig. 7, also include that one divides for the optical fiber being supported fiber optic tap structure Propping up arrangement holding device, it includes that magnet base cross rod frame 51, two branch optical fiber 52, optical fiber and illumination probe adjust frame 53, L-type adjusts frame 54, illumination probe 55, is used for eliminating the illumination probe seal box that illumination photometry is affected by veiling glare 56, two branch optical fiber grip blocks 57 and rubber optical fiber cover 58；The top of magnet base cross rod frame 51 arranges one and has two The rectangle metal derby of individual mutually orthogonal circular hole, the orthocycle through rectangle metal derby is held in collecting of two branch optical fibers 52 Hole is fastened by bolt lock with magnet base cross rod frame 51.Optical fiber and illumination probe adjust frame 53 and include a base 531, Base 531 top is fixedly installed a support bar 532, and the top of support bar 532 is fixedly installed L-type and adjusts frame 54, L Type adjusts the outside of frame 54 and is fixedly installed illumination probe seal box 56, and the bottom of L-type adjustment frame 54 is fixedly installed to be had Two branch optical fiber grip blocks 57 of manhole；Two branch optical fibers 52 wherein one be branching through illumination probe seal box 56 connect illumination probe 55, and another branch optical fiber is passed the circular hole of two points of optical fiber grip blocks 57 and locked by bolt Fix, and the outer end of another branch optical fiber is socketed a rubber optical fiber cover 58.
In the various embodiments described above, as shown in Figure 8, the birds visual stimulus light analysis record system of the present invention is used to carry out During experiment, also include that one for the fiber optic tap arrangement holding device being supported fiber optic tap structure, it includes magnetic Power seat cross rod frame 61, photodiode amplifying circuit contact pin line sheath 62, photodiode amplifying circuit 63, Optical fiber and photodiode amplifying circuit adapter sleeve 64, two branch optical fiber 65, bleeding-stopping dressing 66, two branch optical fiber are recessed Groove grip block 67 and three-dimensional mobile platform bridge 68.The top of magnet base cross rod frame 61 arranges one and has two mutually The rectangle metal derby of orthogonal circular hole, one end of photodiode amplifying circuit contact pin line sheath 62 is through rectangle gold Belonging to block circular hole and be locked with magnet base cross rod frame 61 by bolt, photodiode amplifying circuit contact pin line protects The other end of set 62 connects photodiode amplifying circuit 63, and photodiode amplifying circuit 63 is by optical fiber and photoelectricity Diode amplifying circuit adapter sleeve 64 connects a wherein branch end of two branch optical fibers 65, another of two branch optical fibers 65 Branch optical fiber connects sepectrophotofluorometer, and two branch optical fibers collect the fixing bleeding-stopping dressing 66 that connects of end (time actually used Casing can be rolled into bleeding-stopping dressing and collect end at two branch optical fibers), bleeding-stopping dressing 66 is for inserting birds inside ofeye Time absorb wound surface exudate, prevent diffusate cover at optical fiber surface.Collecting of two branch optical fibers 65 is held by two points Propping up fiber grooves grip block 67 to support, and use lock screw to fix, two branch optical fiber grooves hold blocks 67 are fixing to be put Putting on three-dimensional mobile platform bridge 68, three-dimensional mobile platform bridge 68 is used for adjusting optical fiber and collects end entrance birds eye The position of nest.
The various embodiments described above are merely to illustrate the present invention, and the structure of the most each parts, connected mode and manufacture craft etc. are all Can be varied from, every equivalents carried out on the basis of technical solution of the present invention and improvement, the most should not Get rid of outside protection scope of the present invention.

Claims (11)

1. a birds visual stimulus real-time monitoring system, it is characterised in that: it includes a stereotaxic instrument, a record Electrode, an eeg amplifier, a brain wave acquisition card, a computer, an optical stimulus signal generator, a LED are to light Structure, a fiber optic tap structure and illumination probe；Birds are fixed on described stereotaxic instrument, described recording electrode Input be plugged in birds brain district, the output of described recording electrode connects the input of described eeg amplifier, institute The output stating eeg amplifier connects the input of described brain wave acquisition card, and the output of described brain wave acquisition card connects Described computer；
Described optical stimulus signal generator is connected to excite described LED to light to photo structure with described LED by cable Structure sends LED light signal, and described LED collects end for by LED to the photo structure described fiber optic tap structure of connection Optical signal is delivered to each branch end of described fiber optic tap structure, one of them branch end pair of described fiber optic tap structure Quasi-birds eyes are used for transmitting portion LED light signal as light stimulus, the EEG signals quilt that light stimulus produces via birds Being sent to described eeg amplifier after described recording electrode collection, described eeg amplifier passes through described after being amplified by signal Eeg signal acquisition card is sent to computer and carries out real time record analysis；Another branch end of described fiber optic tap structure Part LED light signal being sent to described illumination probe and carries out illuminance detection, described illumination probe is by the telecommunications of detection Number it is returned to described optical stimulus signal generator for monitoring the brightness value of LED light signal by cable.
2. a kind of birds visual stimulus real-time monitoring system as claimed in claim 1, it is characterised in that: when being applicable to During eyes pattern, also include a LED and pop one's head in photo structure, a fiber optic tap structure and an illumination；Described light stimulus Signal generator is connected in parallel two described LED to photo structure, and two described LED send LED light to photo structure simultaneously The described fiber optic tap structure of signal to two collect end, one of them branch end of each described fiber optic tap structure Two eyes being respectively aligned to birds produce via birds as light stimulus, light stimulus for transmitting portion LED light signal EEG signals be sent to described eeg amplifier by after described recording electrode collection, signal is put by described eeg amplifier It is sent to described computer by described brain wave acquisition card after big and carries out real time record analysis；Each described fiber optic tap Part LED light signal is sent to corresponding illumination probe and carries out illuminance detection by another branch end of structure respectively, and two The signal of telecommunication of detection is returned to described optical stimulus signal generator by cable and is used for monitoring LED light by described illumination probe The brightness value of signal.
3. a kind of birds visual stimulus real-time monitoring system as claimed in claim 1 or 2, it is characterised in that: described Optical stimulus signal generator includes a power filtering module, a Switching Power Supply, a timer, light stimulus pattern and a LED Brightness regulating circuit, a left eye LED current display circuit, a right eye LED current display circuit, a left eye light stimulus Illumination circuit, a right eye light stimulus illumination circuit, some switches, some buttons and some connection interfaces；Wherein, Switch includes a photodiode amplifying circuit power switch, a pause switch and a reset switch；Button includes that one is left Eye LED luminance adjusting knob, a stimulus modality select knob, a right eye LED luminance adjusting knob, a brain wave acquisition Current potential adjusts knob, a LED luminance shelves knob, three left eye light stimulus illumination buttons and three right eye light stimulus illumination buttons； Connection interface includes a left eye LED cable interface, a right eye LED cable interface, a left eye light stimulus illumination circuit Cable interface, a right eye light stimulus illumination circuit cable interface, a brain wave acquisition card cable interface, a photodiode Amplifying circuit cable interface and one or six Semi-digital universal meter cable interfaces；
Wherein, the input of described power filtering module connects civil power and is used for being filtered civil power 220V, described power supply The output of filtration module is connected in parallel input and the energization input of described timer of described Switching Power Supply；Described The output of Switching Power Supply connects described light stimulus pattern and the input of LED luminance adjustment circuit, described reset switch Input with described timer is connected respectively with pause switch, described timer output end and described light stimulus pattern and LED luminance adjusts the signal input part of circuit and connects；Described light stimulus pattern and LED luminance adjust the input of circuit It is also associated with some knobs, adjusts the parameter in circuit for changing light stimulus pattern and LED luminance, wherein, described Left eye LED luminance adjusting knob is used for changing left eye LED to LED loop current value in photo structure, described right eye LED Brightness regulation knob is used for changing right eye LED and selects knob to LED loop current value in photo structure, described stimulus modality It is used for adjusting to LED stimulus modality in photo structure, described brain wave acquisition current potential adjustment knob for changing right and left eyes LED Brain electricity sync signal level amplitude, described LED luminance shelves knob is for changing LED to the brightness model of LED in photo structure Enclosing, the output of described light stimulus pattern and LED luminance adjustment circuit is connected in parallel the electricity of photodiode amplifying circuit Source switch, left eye LED current display circuit, right eye LED current display circuit, left eye LED cable interface, right eye LED cable interface, brain wave acquisition card cable interface, photodiode amplifying circuit cable interface and six Semi-digitals ten thousand Use table cable interface；Wherein, the power switch of described photodiode amplifying circuit is used for controlling photodiode amplification Circuit power break-make；Described left eye LED current display circuit is used for showing that left eye LED is to LED loop electricity in photo structure Flow valuve, described right eye LED current display circuit is used for showing that right eye LED is to LED loop current value in photo structure, institute Stating left eye LED cable interface for connecting left eye LED to photo structure, described right eye LED cable interface is used for connecting the right side Eye LED is to photo structure, and described brain wave acquisition card cable interface is used for connecting described brain wave acquisition card and brain electricity being synchronized letter Number adjusting circuit from light stimulus pattern and LED luminance sends into described brain wave acquisition card；Described photodiode amplifying circuit Cable interface is for connecting photodiode amplifying circuit and the signal of telecommunication of conversion being sent to described six Semi-digital general-purposes Table cable interface, described six Semi-digital universal meter cable interfaces are for connecting six Semi-digital universal meters；Described left eye Light stimulus illumination circuit is connected with left eye light stimulus illumination circuit cable interface for being connected left eye illumination probe and by left eye The illumination probe signal of telecommunication is sent to described left eye light stimulus illumination circuit；Described right eye light stimulus illumination circuit and the described right side Eye stimulates illumination circuit cable interface to be connected for connecting right eye illumination probe and being sent by the right eye illumination probe signal of telecommunication To described right eye light stimulus illumination circuit；Described left eye light stimulus illumination button and described left eye light stimulus illumination circuit phase It is used in conjunction in changing described left eye light stimulus illumination circuit parameter, described right eye light stimulus illumination button and described right eye polished bard Swash illumination circuit to be connected for changing right eye light stimulus illumination circuit parameter.
4. a kind of birds visual stimulus real-time monitoring system as claimed in claim 3, it is characterised in that: described polished bard Energizing mode and LED luminance adjust circuit include level shifter interface circuit, sequential logical circuit, multi-strobe circuit, Left/right eye LED precision standard source constant-current drive circuit, LED chip, brain wave acquisition card signal synchronous interface circuit, electricity Source and filter circuit；Described level shifter interface circuit is for being converted to fit by the clock pulse signal CP that timer exports For CMOS level and the signal of Transistor-Transistor Logic level chip operation and produce positive and negative CP clock signal and be sent to described sequential Logic circuit；Described sequential logical circuit is for receiving clock signal that described level shifter interface processing of circuit crosses and producing Clock signal required for life is sent to described multi-strobe circuit；Described multi-strobe circuit will trigger signal and send into institute State left/right eye LED precision standard source constant-current drive circuit as triggering signal, for realizing LED chip stimulus modality Select；Described brain wave acquisition card signal synchronous interface circuit and described multi-strobe circuit are connected to produce and light stimulus The signal of telecommunication synchronized, and the signal of telecommunication described brain wave acquisition card of feeding light stimulus synchronized is as Tong Bu with EEG signals Reference signal；Described power supply and filter circuit are for powering for all circuit chips, and remove chip power and ground offer Coupling capacitor filtering.
5. a kind of birds visual stimulus real-time monitoring system as claimed in claim 4, it is characterised in that: described level Conversion interface circuit is by connector J1, triode Q1, triode Q7, earth resistance R5, earth resistance R24, limit Leakage resistance R3, current-limiting resistance R23, resistance R22, resistance R6, phase inverter U6A, reverser U6B and reverser U6C Composition；Described current-limiting resistance R3 one end connects the output of described plug-in unit J1, and the described current-limiting resistance R3 other end connects The base stage of described triode Q1；Described earth resistance R5 one end connects the base stage of described triode Q1, described ground connection electricity The other end ground connection of resistance R5；Described resistance R6 one end connects the emitter stage of described triode Q1, described resistance R6's Other end ground connection；One end of described current-limiting resistance R23 connects the emitter stage of described triode Q1, described current-limiting resistance The other end of R23 connects the base stage of described triode Q7；One end of described earth resistance R24 connects described triode Q7 Base stage, the other end ground connection of described earth resistance R24；One end of described resistance R22 connects described triode Q7 Colelctor electrode, described resistance R22 another termination 5V power supply；The input of described phase inverter U6A connects described three poles The colelctor electrode of pipe Q7；The input of described phase inverter U6B connects the input of described phase inverter U6A, described phase inverter The output of U6B connects the input of described phase inverter U6C.
6. a kind of birds visual stimulus real-time monitoring system as claimed in claim 5, it is characterised in that: described sequential Logic circuit is by JK flip-flop U4A, JK flip-flop U4B, resistance R12, resistance R13, key switch SV2, resistance R17, resistance R18, key switch SV3, four inputs and door U2A, U2B, U2C and U2D；Described phase inverter U6A Output be connected in parallel described JK flip-flop U4A'sJK flip-flop U4B'sInput and door U2A Input 1A and input and the input 2B of door U2B；The K input of described JK flip-flop U4A, J input 5V power supply is connected with VCC power end；One end of described resistance R12 connects 5V power supply, another of described resistance R12 End connects described JK flip-flop U4A'sOne end of described resistance R13 connects 5V power supply, and the other end connects institute State JK flip-flop U4A'sThe GND ground connection of described JK flip-flop U4A, the Q of described JK flip-flop U4A Output is connected with the input 1B of door U2A with described input, described JK flip-flop U4A'sOutput is with described Input is connected with the input 2A of door U2B；One end of described key switch SV2 connects described JK flip-flop U4A'sThe other end ground connection of described key switch SV2；The J input of described JK flip-flop U4B, K input and VCC power end connects 5V power supply；One end of described resistance R17 connects 5V power supply, the other end of described resistance R17 Connect described JK flip-flop U4B'sOne end of described resistance R18 connects 5V power supply, and the other end connects JK Described trigger U4B'sOne end of described key switch SV3 connects described JK flip-flop U4B's The other end ground connection of described key switch SV3；The Q output of described JK flip-flop U4B connects described input and door The input 4A of U2D, described JK flip-flop U4B'sOutput connects the input 3A of described input and door U2C.
7. a kind of birds visual stimulus real-time monitoring system as claimed in claim 6, it is characterised in that: described multichannel Gating circuit is made up of two-way eight bit switch SW1, the first input end of described two-way eight bit switch SW1 and described input It is connected with the 1Y output of door U2A；Second input is unsettled；3rd input and described input and the 1Y of door U2A Output connects；Four-input terminal is connected with the output of described phase inverter U6A；5th input and described input with The output of door U2D connects；6th input and described JK flip-flop U4B /Q output is connected；7th input End is connected with the Q output of described JK flip-flop U4A；8th input connects with the output of described input with door U2B Connect；9th input is unsettled；Tenth input is connected with the output of described input with door U2B；11st input It is connected with the output of described input with door U2B；12nd input is connected with the output of described phase inverter U6A； 13rd input is connected with the Q output of described JK flip-flop U4B；Tenth four-input terminal and described input and door The output of U2C connects；15th input is connected with the output of described input with door U2A；16th input With described JK flip-flop U4A /Q output is connected；17th output drives with described LED precision standard source constant current The input 1B of dynamic one end of resistance R20 of circuit, input or door U3A connects；18th output and described LED One end of the resistance R11 of precision standard source constant-current drive circuit, input are connected with the input 1A of door U3A.
8. a kind of birds visual stimulus real-time monitoring system as claimed in claim 7, it is characterised in that: described LED Precision standard source constant-current drive circuit includes voltage-reference U1, voltage-reference U5, resistance R1, resistance R2, electricity Resistance R10, resistance R11, resistance R14, resistance R15, resistance R16, resistance R19, resistance R20, resistance R21, Resistance R25, resistance R26, triode Q3, triode Q4, triode Q5, triode Q6, LED are in photo structure LED chip D2, LED to LED chip D3 in photo structure, LED luminance adjusting knob W1, LED luminance regulation Knob W3, LED current display circuit J3, LED current display circuit J4 and two-way two-position switch SW4；Described resistance The other end of R11 connects the base stage of described triode Q4；One end of described resistance R14 connects described triode Q4's Base stage, other end ground connection；The grounded emitter of described triode Q4；The colelctor electrode of described triode Q4 is connected in parallel Described resistance R2 and one end of resistance R10, the other end of described resistance R2 connects with the negative electrode of described voltage-reference U1 Connecing, the other end of described resistance R10 is connected with the anode of described voltage-reference U1, described voltage-reference U1's Negative electrode is connected in parallel 12V power supply, resistance R1 and one end of resistance R25；The other end of described resistance R1 is double with described One group of normally opened contact of road two-position switch SW4 connects, the other end of described resistance R25 and described two-way two-position switch SW4 One group of normally-closed contact connect, one group of common port of described two-way two-position switch SW4 and described LED luminance adjusting knob The sliding end of W1 connects, and the fixing end of described LED luminance adjusting knob W1 is connected with the emitter stage of described triode Q3, The base stage of described triode Q3 is connected with the anode of described voltage-reference U1, the colelctor electrode of described triode Q3 and institute Stating LED to connect to the anode of LED chip D2 in photo structure, described LED is to LED chip D2 in photo structure Negative electrode is connected with the signal input part of LED current display circuit J3, the signal ground of described LED current display circuit J3 With power supply ground ground connection, power supply connects 5V power supply, one end of described resistance R20 and the base stage of described triode Q6, resistance One end of R21 connects, the other end ground connection of described resistance R21, described triode Q6 grounded emitter, described three poles The colelctor electrode of pipe Q6 is connected with one end, one end of resistance R19 of resistance R16, the other end of described resistance R16 and institute The negative electrode stating voltage-reference U5 connects, and the other end of described resistance R19 connects with the anode of described voltage-reference U5 Connecing, the negative electrode of described voltage-reference U5 is connected with 12V power supply, one end of resistance R15, one end of resistance R26； Another group normally opened contact of the other end of described resistance R26 and described two-way two-position switch SW4 is connected, resistance R15 The other end is connected with another group normally-closed contact of two-way two-position switch SW4, another group of described two-way two-position switch SW4 Common port is connected with the sliding end of described LED luminance adjusting knob W3, the fixing end of LED luminance adjusting knob W3 with The emitter stage of triode Q5 connects, and the base stage of described triode Q5 is connected with the anode of described voltage-reference U5, institute The colelctor electrode stating triode Q5 is connected to the anode of LED chip D3 in photo structure with described LED, and described LED gives The signal ground of the negative electrode of LED chip D3 in photo structure and LED current display circuit J4 and power supply ground ground connection, power supply Connect 5V power supply.
9. a kind of birds visual stimulus as described in claim 1 or 2 or 4 or 5 or 6 or 7 or 8 monitors system in real time System, it is characterised in that: to photo structure, described LED includes that magnet base cross rod frame, LED support bar, LED support bar are even Female connector, two core cable plug female, two core cable plug male plug, LED and aluminium base and LED lamp cover；Described The top of magnet base cross rod frame arranges a rectangle metal derby with two mutually orthogonal circular holes, and described LED supports Bar is fastened by bolt lock through the orthogonal hole of rectangle metal derby with described magnet base cross rod frame；Described LED props up One end of strut is arranged with described LED support rod connecting sleeve, and the outer end of described LED support rod connecting sleeve is by screw thread even Connecing described two core cable plug male, it is female that described two core cable plug male connects described two core cable plug by contact pin Head, the other end of described LED support bar is threaded connection described LED and aluminium base, described LED and aluminium base Outside sheathed described LED lamp cover, described LED positive pole connects a two core cable wherein cable, and LED negative pole connects two Another root cable in core cable.
10. a birds visual stimulus light analysis record system, it is characterised in that: it include a stereotaxic instrument, one Optical stimulus signal generator, a LED are to photo structure, an optical fiber structure, a fiber optic tap structure, a light intensity test mould Block, a sepectrophotofluorometer and a computer；
Birds are fixed on described stereotaxic instrument, and described optical stimulus signal generator passes through cable with described LED to light Structure is connected to excite LED to send LED light signal to photo structure, and described LED connects described optical fiber knot to photo structure The input of structure, wherein eyes of the output alignment birds of described optical fiber structure are used for sending LED light signal and make For light stimulus, the LED light signal of decay is sent to described fiber optic tap structure by the eye socket of the another eyes of birds Collecting end, collect end and the LED light signal of decay from birds eye socket is passed to each branch end, described fiber optic tap is tied The part LED light signal of reception is sent to described light intensity test module by one of them branch end of structure, and described light intensity is surveyed The optical signal received is converted to voltage signal and is sent to described optical stimulus signal generator by die trial block；Described optical fiber divides The part LED light signal of reception is sent to described sepectrophotofluorometer by another fiber optic tap end propping up structure, described Sepectrophotofluorometer carries out spectral scan to the LED light signal received, and spectral scan result is sent to described meter Calculation machine is analyzed.
11. a kind of birds visual stimulus light analysis record systems as claimed in claim 10, it is characterised in that: also wrap Including one for the fiber optic tap arrangement holding device being supported described fiber optic tap structure, it includes that magnet base intersects Bridge, photodiode amplifying circuit contact pin line sheath, photodiode amplifying circuit, optical fiber and photodiode Amplifying circuit adapter sleeve, two branch optical fibers, bleeding-stopping dressing, two branch optical fiber grooves hold block and three-dimensional mobile platform bars Frame；The top of described magnet base cross rod frame arranges a rectangle metal derby with two mutually orthogonal circular holes, described One end of photodiode amplifying circuit contact pin line sheath is through described rectangle metal derby circular hole and by bolt and institute Stating magnet base cross rod frame to be locked, the other end of described photodiode amplifying circuit contact pin line sheath connects institute Stating photodiode amplifying circuit, described photodiode amplifying circuit amplifies electricity by described optical fiber with photodiode Road adapter sleeve connects a wherein branch end of described two branch optical fibers, and another branch optical fiber of described two branch optical fibers connects Described sepectrophotofluorometer, the end that collects of described two branch optical fibers fixes connection bleeding-stopping dressing；Described two branch optical fibers The end that collects support fixing by described two branch optical fiber grooves hold blocks, described two branch optical fiber grooves hold blocks are fixed It is placed on described three-dimensional mobile platform bridge.
CN201410482583.6A 2013-09-26 2014-09-19 A kind of birds visual stimulus monitors and light analysis record system in real time Active CN104224128B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410482583.6A CN104224128B (en) 2013-09-26 2014-09-19 A kind of birds visual stimulus monitors and light analysis record system in real time

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN201310444773 2013-09-26
CN2013104447734 2013-09-26
CN201310444773.4 2013-09-26
CN201410482583.6A CN104224128B (en) 2013-09-26 2014-09-19 A kind of birds visual stimulus monitors and light analysis record system in real time

Publications (2)

Publication Number Publication Date
CN104224128A CN104224128A (en) 2014-12-24
CN104224128B true CN104224128B (en) 2016-08-24

Family

ID=52213683

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410482583.6A Active CN104224128B (en) 2013-09-26 2014-09-19 A kind of birds visual stimulus monitors and light analysis record system in real time

Country Status (1)

Country Link
CN (1) CN104224128B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106249846B (en) * 2015-06-29 2020-03-17 北京智谷睿拓技术服务有限公司 Light intensity adjusting method and device
CN106489790B (en) * 2016-10-25 2019-03-15 郑州大学 Birds visual cognition learning training system
CN111134669A (en) * 2020-04-08 2020-05-12 成都泰盟软件有限公司 Visual evoked potential acquisition method and device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1248426A (en) * 1999-10-29 2000-03-29 清华大学 Controller based on brain electricity steady-state induced response
US6577886B1 (en) * 2001-08-15 2003-06-10 Olympus Optical Co., Ltd. Living body function measurement method
CN1491610A (en) * 2002-10-22 2004-04-28 株式会社日立制作所 Living body measuring system
CN101569778A (en) * 2009-03-10 2009-11-04 深圳先进技术研究院 Biofeedback simulation system and biofeedback simulation method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1248426A (en) * 1999-10-29 2000-03-29 清华大学 Controller based on brain electricity steady-state induced response
US6577886B1 (en) * 2001-08-15 2003-06-10 Olympus Optical Co., Ltd. Living body function measurement method
CN1491610A (en) * 2002-10-22 2004-04-28 株式会社日立制作所 Living body measuring system
CN101569778A (en) * 2009-03-10 2009-11-04 深圳先进技术研究院 Biofeedback simulation system and biofeedback simulation method

Also Published As

Publication number Publication date
CN104224128A (en) 2014-12-24

Similar Documents

Publication Publication Date Title
JP4451899B2 (en) Digitally controlled lighting method and system
CN104107051B (en) Portable multiple brain region blood oxygen detection and real-time display system
CN104224128B (en) A kind of birds visual stimulus monitors and light analysis record system in real time
CN204072050U (en) A kind of Portable Chinese medicine picture of the tongue numeralization collecting device
CN203763052U (en) Mammary tissue detector and detection probe thereof
CN202535920U (en) Device for researching on phototactic behavior of small fish
CN101664598A (en) Photoelectric chessboard and use method thereof
CN203634167U (en) Medical device
CN108324241A (en) Multispectral light source, eyeground imaging system and imaging method
CN104545815B (en) A kind of facial spectral reflectivity restored method based on multispectral video
CN106157598B (en) Wireless infrared remote control optogenetic system
CN206543179U (en) Eeg signal acquisition system
CN209285472U (en) A kind of acquisition device
KR20140053487A (en) Therapy lighting apparatus
CN104735869A (en) Lamplight control system based on vision comfort level and control method
CN102885613A (en) Biological safety detection method for LED (light-emitting diode) light
CN110503908A (en) A kind of POV shows exchange method and system
CN203705052U (en) Portable LED dental standard colorimetric light source
CN203354516U (en) Multifunctional oral cavity digital observation instrument
RU2429779C2 (en) Diagnostic technique for human and animal organ conditions and device for its implementation
CN206559694U (en) The crack lamp lighting apparatus of ophthalmic operating microscope
CN200991228Y (en) Vision temporary-keeping characteristic detector
CN215219124U (en) Power-on control testing device based on DS1286
Mota et al. Portable, low-cost, lensless DHM system using RGB LEDs
CN101847335B (en) Simulating probe in single photon emission computed tomography (SPECT) system

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant