CN101563344B - 新颖的色烯-2-酮衍生物和它们作为单胺神经递质再摄取抑制剂的用途 - Google Patents

新颖的色烯-2-酮衍生物和它们作为单胺神经递质再摄取抑制剂的用途 Download PDF

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Publication number
CN101563344B
CN101563344B CN2007800472000A CN200780047200A CN101563344B CN 101563344 B CN101563344 B CN 101563344B CN 2007800472000 A CN2007800472000 A CN 2007800472000A CN 200780047200 A CN200780047200 A CN 200780047200A CN 101563344 B CN101563344 B CN 101563344B
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China
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disorder
pain
syndrome
compound
base
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Expired - Fee Related
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CN2007800472000A
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English (en)
Chinese (zh)
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CN101563344A (zh
Inventor
D·佩特斯
J·P·雷德罗伯
G·M·欧尔森
E·O·尼尔森
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NTG Nordic Transport Group AS
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Neurosearch AS
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Priority claimed from PCT/EP2007/064130 external-priority patent/WO2008074797A1/en
Publication of CN101563344A publication Critical patent/CN101563344A/zh
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Publication of CN101563344B publication Critical patent/CN101563344B/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN2007800472000A 2006-12-20 2007-12-18 新颖的色烯-2-酮衍生物和它们作为单胺神经递质再摄取抑制剂的用途 Expired - Fee Related CN101563344B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US87580606P 2006-12-20 2006-12-20
DKPA200601678 2006-12-20
US60/875,806 2006-12-20
DKPA200601678 2006-12-20
PCT/EP2007/064130 WO2008074797A1 (en) 2006-12-20 2007-12-18 Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Publications (2)

Publication Number Publication Date
CN101563344A CN101563344A (zh) 2009-10-21
CN101563344B true CN101563344B (zh) 2011-11-16

Family

ID=40639626

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2007800472000A Expired - Fee Related CN101563344B (zh) 2006-12-20 2007-12-18 新颖的色烯-2-酮衍生物和它们作为单胺神经递质再摄取抑制剂的用途

Country Status (12)

Country Link
KR (1) KR20090089439A (de)
CN (1) CN101563344B (de)
AR (1) AR064457A1 (de)
AT (1) ATE486868T1 (de)
BR (1) BRPI0719578A2 (de)
DE (1) DE602007010356D1 (de)
DK (1) DK2121677T3 (de)
NZ (1) NZ577071A (de)
PT (1) PT2121677E (de)
RU (1) RU2009119919A (de)
TW (1) TW200836732A (de)
ZA (1) ZA200903278B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4159725A4 (de) 2020-05-29 2023-12-20 Daegu-Gyeongbuk Medical Innovation Foundation Carboxamidderivat und pharmazeutische zusammensetzung damit als wirkstoff zur vorbeugung oder behandlung von geisteskrankheiten
CN116057053A (zh) 2020-05-29 2023-05-02 大邱庆北尖端医疗产业振兴财团 含至少一个n的5元杂芳基衍生物和含其为活性成分用于预防或治疗精神障碍的药物组合物
US20230212121A1 (en) 2020-05-29 2023-07-06 Daegu-Gyeongbuk Medical Innovation Foundation Sulfonamide derivative and pharmaceutical composition comprising same as active ingredient for preventing or treating mental illness

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006035034A1 (en) * 2004-09-30 2006-04-06 Neurosearch A/S Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006035034A1 (en) * 2004-09-30 2006-04-06 Neurosearch A/S Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Also Published As

Publication number Publication date
KR20090089439A (ko) 2009-08-21
PT2121677E (pt) 2011-01-25
ATE486868T1 (de) 2010-11-15
CN101563344A (zh) 2009-10-21
ZA200903278B (en) 2010-07-28
RU2009119919A (ru) 2011-01-27
BRPI0719578A2 (pt) 2013-12-17
DK2121677T3 (da) 2011-02-07
NZ577071A (en) 2011-07-29
AR064457A1 (es) 2009-04-01
TW200836732A (en) 2008-09-16
DE602007010356D1 (de) 2010-12-16

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Granted publication date: 20111116

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