CN101559146B - Oral Tonglin Paishi capsule for curing urinary calculi and preparation method thereof - Google Patents
Oral Tonglin Paishi capsule for curing urinary calculi and preparation method thereof Download PDFInfo
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- CN101559146B CN101559146B CN2008100506107A CN200810050610A CN101559146B CN 101559146 B CN101559146 B CN 101559146B CN 2008100506107 A CN2008100506107 A CN 2008100506107A CN 200810050610 A CN200810050610 A CN 200810050610A CN 101559146 B CN101559146 B CN 101559146B
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Abstract
The invention relates to a drug used for curing urinary calculi, in particular to an oral Tonglin Paishi capsule prepared by taking Chinese herbal medicines as raw materials and used for curing the urinary calculi. The drug is prepared by taking ten Chinese herbal medicines, such as loosestrife, chicken gizzardskin, Chinese teasel roots, glauber salt, immature citron fruits, magnolia bark, semen vaccariae, pangolin, plantain and alisma, as the raw materials, as well as nine processing steps, such as material selecting, cleaning, drying, grinding, sieving, mixing, capsule filling, split charging and packing. According to the clinical observation, the oral Tonglin Paishi capsule has the advantages of good and fast curative effect and high curative ratio for curing the urinary calculi, simple manufacture, convenient taking, low cost, and the like.
Description
Technical field
The present invention relates to a kind of medicine of treating urinary system calculus, a kind of specifically is the oral Tonglin Paishi capsule of the treatment treatment urinary system calculus of feedstock production with the Chinese herbal medicine, the invention still further relates to the method for preparing of this medicine.
Background technology
Urinary system calculus is some crystal things (like calcium, oxalic acid, uric acid, cystine etc.) and has substrate (like stromatin, acidic mucopolysaccharide etc.) to build up caused disease unusually.In recent years, along with improving constantly of China's living standards of the people, the sickness rate of urinary system calculus increases year by year.Be more common in adult male; The ratio of China men and women morbidity is 4: 1; Often occur in the person between twenty and fifty in 20-50 year, urinary calculi can cause urinary tract infection and obstruction, if the calculus incarceration is in renal pelvis, ureter intersection or ureter; Then produce hydronephrosis, pyelectasis, renal cortex atrophy and destruction, cause hematuria, renal colic, urine sense, renal failure etc.Though the Chinese patent medicine of some treatment primary disease and the application of extracorporeal shock-wave lithotomy are arranged at present, because effect is not fairly obvious, it is healthy to have a strong impact on patient's body.
Summary of the invention
The objective of the invention is to provide a kind of clearing away heat-damp and promoting diuresis that has, the oral Tonglin Paishi capsule of the treatment urinary system calculus of Tonglin Paishi.
Another object of the present invention provides the method for preparing of the oral Tonglin Paishi capsule of this treatment urinary system calculus.
The objective of the invention is to realize like this:
This medicine is the medicament of being processed by following raw materials by weight proportions:
Herba Lysimachiae 10-30 part Endothelium Corneum Gigeriae Galli 10-25 part Radix Et Rhizoma Rhei 10-20 part Natrii Sulfas 10-20 part
Fructus Aurantii Immaturus 10-20 part Cortex Magnoliae Officinalis 10-20 part Semen Vaccariae 10-20 part Squama Manis 5-15 part
Herba Plantaginis 10-20 part Rhizoma Alismatis 10-20 part.
The weight proportion scope of preparation medicine of the present invention is:
Herba Lysimachiae 10-20 part Endothelium Corneum Gigeriae Galli 10-20 part Radix Et Rhizoma Rhei 10-15 part Natrii Sulfas 10-15 part
Fructus Aurantii Immaturus 10-15 part Cortex Magnoliae Officinalis 10-15 part Semen Vaccariae 10-15 part Squama Manis 5-10 part
Herba Plantaginis 10-15 part Rhizoma Alismatis 10-15 part.
The weight proportion of medicine of the present invention is:
12 parts of 12 parts of Fructus Aurantii Immaturuss of 12 parts of Natrii Sulfas of 12 parts of Radix Et Rhizoma Rhei of 15 parts of Endothelium Corneum Gigeriae Galli of Herba Lysimachiae
12 parts of 12 portions of Rhizoma Alismatis of 6 portions of Herba Plantaginiss of 12 parts of Squama Maniss of 12 parts of Semen Vaccariae of Cortex Magnoliae Officinalis
Above-mentioned each component is processed production of medicine method of the present invention is:
This method for preparing through select materials, clean, dry, grind, sieve, mixing, encapsulated, packing, nine steps of packing accomplish.
Above-mentioned Chinese medicine at first will through selecting materials, clean, process such as drying; When drying, to do, grind then, after sieve in dry in the sun under the sun or at low temperature flood below 60 ℃; Reach 100 orders, mix then, encapsulated, packing, pack and promptly accomplished whole process of preparation at last.
When processing this medicine, require to accomplish aseptic in packer's bay and the storeroom, free from dampness.
The present invention has the curative effect height through clinical observation, instant effect, and cure rate is high, taking convenience, advantage such as expense is low.
Function: clearing away heat-damp and promoting diuresis, Tonglin Paishi.
Cure mainly: urinary system calculus.
Usage and consumption: oral.A 8-10 grain, 3 times on the one.
The clinical case visual report of medicine of the present invention
The medicine Tonglin Paishi capsule of this treatment urinary system calculus is the Chinese medicinal capsule preparation, and this medical instrument has the effect of clearing away heat-damp and promoting diuresis, Tonglin Paishi.Observe this invention medicines through 266 routine clinical cases and is treating advantage such as have the curative effect height aspect the urinary system calculus, have no side effect the court.
One, case is selected
19-30 year 42 examples among the 266 routine urinary system calculus patients; 31-40 year 79 examples; 41-50 year 62 examples; 51-60 year 51 examples; 61-72 year 32 examples.
Two, diagnostic criteria
" Chinese medicine clinical pharmacology " diagnostic criteria according to Weng Weiliang chief editor in 2002
Lithangiuria comprises renal calculus, ureteral calculus, vesical calculus and calculus of urethra.After comprising results such as medical history, symptom, physical examination, uroscopy, blood testing, renal function mensuration, X ray examination, cystoscopy, ultrasound investigation and ING inspection at analysis-by-synthesis, its diagnosis just can make.
1, medical history and symptom have kidney and the ureteral colic that the typical case breaks out, companion's naked eyes and microscopic hematuria; Or the waist and belly dull pain is only arranged, acid is expanded uncomfortable, or the calculus history is arranged; Bladder, calculus of urethra then have dysuria, and urine stream interrupts symptoms such as urine retention and terminal hematuria.
2, pain or tenderness are kowtowed in kidney district or ureter position during the sign acute attack; Giant hydronephrosis, renal abscess patient can lay one's hand on and enclosed mass; Big vesical calculus often can footpath rectum touch be touched; Back calculus of urethra, rectal touch can be touched; Penis inspection can touch the anterior urethra calculus.
3, X ray examination 95% lithangiuria develops on abdominal part X plain film, can show size, form, the number of calculus, and the composition of calculus according to a preliminary estimate.The plain film feminine gender still can not get rid of the lithangiuria fully person; Need make excretory urography or ascending urography; Understanding the position that has that it's too late of calculus, and anatomic forms such as renal pelvis, renal calices, ureter be can further understand, hydronephrosis and degree thereof had or not; Excess of the kidney matter thickness, last urinary tract have or not birth defect and other organic diseases.
4, uroscopy urine R-RBC often increases to some extent, especially increases significantly after angor outbreak back or the motion, very then gross hematuria.The saline crystallization body can appear, visible more leukocyte or pus cell during accompanying infection.
5, the ING inspection can reflect the existence and the degree thereof of renal function situation and last urinary tract obstruction.
6, the existence of ultrasound investigation auxiliary diagnosis calculus and size thereof, position, hydronephrotic degree.
7, other also need make the relevant biochemical analysis of blood, urine, need go cystoscopy in case of necessity, comprise retrograde urography etc.
Three, criterion of therapeutical effect
" Chinese medicine clinical pharmacology " curative effect determinate standard according to Weng Weiliang chief editor in 2002
Recovery from illness: calculus is discharged, and collects the calculus BIAO and BEN, the check plain abdominal radiograph, and the calculus shade disappears; Though or do not collect the calculus BIAO and BEN, in certain urinates process, have tangible calculus to discharge sense, check abdomen plain film calculus shade disappears; Though or do not have tangible calculus and discharge sense, long-term no conscious sympton is repeatedly checked plain film, the calculus shade disappears, the contrast examination result is negative, kidney figure, ultrasound diagnosis all show blocks releasing, hydrops alleviates or disappears.
Produce effects: calculus is discharged more than 2/3 or position and is moved down more than 2 cones or more than the 6cm; Hydronephrosis disappears or obviously reduces, and symptom obviously alleviates.
Effectively: descend 1 cone or more than the 3cm of ureteral calculus; Or multiple calculus is partly discharged; Though or the calculus nothing is mobile, the Ipsilateral hydronephrosis alleviates after treatment; Or continuously plain film is observed, disclose and diminish (get rid of because of calculus rotation, projection angle change due to the change of plain film reduction calculus size), or the calculus cracking occurs and dissolve broken phenomenon; Concurrent urinary system infection alleviates, and subjective symptoms has certain alleviating.
Invalid: calculus does not have eliminating or does not have and move, or 1 cone of mobile less than or not enough 3c m; Concurrent hydronephrosis, block, urinary system infection etc. loses and alleviates, even increase the weight of day by day; Renal function is further impaired; Subjective symptoms does not have improvement.
Four, usage and dosage
Oral Tonglin Paishi capsule.A 8-10 grain, 3 times on the one, 30 days is a course of treatment.
Five, conclusion analysis
Oral Tonglin Paishi capsule treatment urinary system calculus 266 examples are observed, and see the following form:
| Age | Case load | Cure rate | Produce effects | Effectively | Invalid |
| 19-30 31-40 41-50 51-60 61-72 adds up to | 42 79 62 51 32 266 | 26(61.9％) 51(64.56％) 43(69.35％) 32(62.75％) 18(56.25％) 170(63.91％) | 8(19.05％) 15(18.99％) 10(16.13％) 9(17.65％) 5(15.63％) 47(17.67％) | 5(11.9％) 8(10.13％) 6(9.68％) 8(15.69％) 7(21.88％) 34(12.78％) | 3(7.14％) 5(6.33％) 3(4.84％) 2(3.92％) 2(6.25％) 15(5.64％) |
Can find out that from table this medicine is cured 170 examples, cure rate 63.91% to the treatment urinary system calculus; Produce effects 47 examples, obvious effective rate 17.67%; Effective 34 examples, effective percentage 12.78%; Invalid 15 examples, inefficiency 5.64%.
Description of drawings
Fig. 1 is preparation technology's flow chart of medicine of the present invention.
The specific embodiment
The method for preparing of from Fig. 1, learning this medicine through select materials, clean, dry, grind, sieve, mixing, encapsulated, packing, nine steps of packing accomplish.At first choose raw material: 15 kilograms of Herba Lysimachiaes, 12 kilograms of Endothelium Corneum Gigeriae Galli, 12 kilograms of Radix Et Rhizoma Rhei, 12 kilograms in Natrii Sulfas, 12 kilograms of Fructus Aurantii Immaturuss, 12 kilograms of Cortex Magnoliae Officinalis, 12 kilograms of Semen Vaccariae, 6 kilograms of Squama Maniss, 12 kilograms of Herba Plantaginiss, 12 kilograms of Rhizoma Alismatis according to proportioning dosage; Clean set by step, dry, when drying, to dry below 60 ℃ in dry in the sun under the sun or low temperature; And then grind, after sieve, to reach 100 orders; Mix, encapsulated, packing, pack, accomplish whole processing step at last; This medicine is with every dress 0.25g preparation, 100 every bottle.
Claims (4)
1. oral Tonglin Paishi capsule of treating urinary system calculus, it is characterized in that: this medicine is the medicament of being processed by following raw materials by weight proportions:
Herba Lysimachiae 10-30 part Endothelium Corneum Gigeriae Galli 10-25 part Radix Et Rhizoma Rhei 10-20 part Natrii Sulfas 10-20 part
Fructus Aurantii Immaturus 10-20 part Cortex Magnoliae Officinalis 10-20 part Semen Vaccariae 10-20 part Squama Manis 5-15 part
Herba Plantaginis 10-20 part Rhizoma Alismatis 10-20 part;
Method for preparing through select materials, clean, dry, grind, sieve, mixing, encapsulated, packing, nine steps of packing accomplish.
2. a kind of oral Tonglin Paishi capsule of treating urinary system calculus according to claim 1 is characterized in that: the weight proportion scope of medicine is:
Herba Lysimachiae 10-20 part Endothelium Corneum Gigeriae Galli 10-20 part Radix Et Rhizoma Rhei 10-15 part Natrii Sulfas 10-15 part
Fructus Aurantii Immaturus 10-15 part Cortex Magnoliae Officinalis 10-15 part Semen Vaccariae 10-15 part Squama Manis 5-10 part
Herba Plantaginis 10-15 part Rhizoma Alismatis 10-15 part.
3. a kind of oral Tonglin Paishi capsule of treating urinary system calculus according to claim 1, it is characterized in that: the weight proportion of medicine is:
12 parts of 12 parts of Fructus Aurantii Immaturuss of 12 parts of Natrii Sulfas of 12 parts of Radix Et Rhizoma Rhei of 15 parts of Endothelium Corneum Gigeriae Galli of Herba Lysimachiae
12 parts of 12 portions of Rhizoma Alismatis of 6 portions of Herba Plantaginiss of 12 parts of Squama Maniss of 12 parts of Semen Vaccariae of Cortex Magnoliae Officinalis.
4. a kind of method for preparing of treating the oral Tonglin Paishi capsule of urinary system calculus according to claim 1 is characterized in that: choose raw material, cleaning, drying in proportion, when drying, will dry below 60 ℃ in dry in the sun under the sun or at low temperature; Grind then,, reach 100 orders after sieve; Mix encapsulated, packing then; Pack at last and promptly accomplished whole preparation process, when processing this medicine, require to accomplish aseptic in packer's bay and the storeroom, free from dampness.
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| CN2008100506107A CN101559146B (en) | 2008-04-17 | 2008-04-17 | Oral Tonglin Paishi capsule for curing urinary calculi and preparation method thereof |
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| CN101559146B true CN101559146B (en) | 2012-03-14 |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1127128A (en) * | 1995-09-14 | 1996-07-24 | 隋嫣玲 | Traditional Chinese medicine for cholelithiasis and preparing method |
| CN1132643A (en) * | 1995-12-01 | 1996-10-09 | 冯学祯 | Medicine for diseases of liver and gall |
| CN1586524A (en) * | 2004-07-25 | 2005-03-02 | 夏光福 | External medicine for treating lithiasis |
| CN1723919A (en) * | 2005-07-20 | 2006-01-25 | 王友富 | Medicine for treating urinary system stone disease, and its prepn. method |
| CN1868531A (en) * | 2005-05-23 | 2006-11-29 | 宿连存 | Traditional Chinese medicine composition for treating hepatolith |
-
2008
- 2008-04-17 CN CN2008100506107A patent/CN101559146B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1127128A (en) * | 1995-09-14 | 1996-07-24 | 隋嫣玲 | Traditional Chinese medicine for cholelithiasis and preparing method |
| CN1132643A (en) * | 1995-12-01 | 1996-10-09 | 冯学祯 | Medicine for diseases of liver and gall |
| CN1586524A (en) * | 2004-07-25 | 2005-03-02 | 夏光福 | External medicine for treating lithiasis |
| CN1868531A (en) * | 2005-05-23 | 2006-11-29 | 宿连存 | Traditional Chinese medicine composition for treating hepatolith |
| CN1723919A (en) * | 2005-07-20 | 2006-01-25 | 王友富 | Medicine for treating urinary system stone disease, and its prepn. method |
Non-Patent Citations (5)
| Title |
|---|
| 周同.泌尿系统结石的辨治体会.《南京中医药大学学报》.1999,第15卷(第4期),242-243. * |
| 张春艳等.消坚排石汤治疗泌尿系统结石36例.《云南中医学院学报》.2007,第30卷(第4期),52-53. * |
| 徐海波等.排石汤配合金钱草泡茶代饮治疗泌尿系统结石.《中国实用医药》.2007,第2卷(第19期),93-94. * |
| 李华荣.中药治疗泌尿系统结石的中文文献分析.《医院药学》.2001,第10卷(第11期),41-42. * |
| 赵鹏.通淋排石补肾活血利气疏导法治疗泌尿系统结石初探.《中国民族民间医药杂志》.2006,(第79期),85-86. * |
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