CN101559144B - Oral Tonglin Hushen capsule for curing urethritis, cystitis, acute pyelonephritis and chronic pyelonephritis and preparation method thereof - Google Patents

Oral Tonglin Hushen capsule for curing urethritis, cystitis, acute pyelonephritis and chronic pyelonephritis and preparation method thereof Download PDF

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Publication number
CN101559144B
CN101559144B CN2008100506075A CN200810050607A CN101559144B CN 101559144 B CN101559144 B CN 101559144B CN 2008100506075 A CN2008100506075 A CN 2008100506075A CN 200810050607 A CN200810050607 A CN 200810050607A CN 101559144 B CN101559144 B CN 101559144B
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cystitis
herba
urethritis
capsule
oral
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CN101559144A (en
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王守东
王守星
王守永
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Abstract

The invention relates to an oral Tonglin Hushen capsule prepared by taking Chinese herbal medicines as raw materials and used for curing urethritis, cystitis, acute pyelonephritis and chronic pyelonephritis. Taking eight Chinese herbal medicines such as corktree, herba violae, armstrong, dianthus superbus, pyrrosia lingua, dandelion, asiatic plantain seeds and licorice as the raw materials, the capsule is obtained by nine processing steps, such as material selecting, cleaning, drying, grinding, sieving, mixing, capsule filling, split charging and packing. According to the clinical observation,the oral Tonglin Hushen capsule has the advantages of good and fast curative effect and high curative ratio for curing the urethritis, the cystitis, the acute pyelonephritis and the chronic pyeloneph ritis, simple manufacture, convenient taking, low cost, and the like.

Description

A kind of oral capsule of treating urethritis and cystitis and preparation method thereof
Technical field
The present invention relates to a kind of medicine of treating urethritis, cystitis and acute and chronic pyelonephritis; A kind of specifically is the oral medicine nephritis capsule of treatment treatment urethritis, cystitis and the acute and chronic pyelonephritis of feedstock production with the Chinese herbal medicine, the invention still further relates to the method for preparing of this medicine.
Background technology
Urinary tract infection is common diseases of urinary system, refer to pathogen in body, urinate in growth and breeding, and invade mucous membrane of urethra or tissue and the inflammation that causes.Primary disease can betide each age group, and is the most common with the women especially, the urinary tract infection of about 3% women more than once taking place once in life, and bachelorette sexually transmitted disease (STD) rate is about 2%, and married woman's sickness rate increases to 5%, and is relevant with sexual life.Anemia of pregnant woman's bacteriuria incidence rate is about 7%; Elderly woman and male's urine infects can be up to 10%; Can it be divided into upper urinary tract infection (acute or chronic pyelonephritis) and lower urinary tract infection (cystitis and urethritis) according to the infection site difference, but be difficult to sometimes completely distinguish.Wherein cystitis accounts for the 50%-70% of urinary tract infection.At present, the clinician mostly adopts western medicine, but more with the side effect behind the Western medicine, part patient's incompatibility western medicine.
Summary of the invention
The objective of the invention is to provide a kind of treatment urethritis, the oral Tonglin Hushen capsule of cystitis and acute and chronic pyelonephritis with eliminating damp-heat, Tonglin Hushen.
Another object of the present invention provides this treatment urethritis, the method for preparing of the oral Tonglin Hushen capsule of cystitis and acute and chronic pyelonephritis.
The objective of the invention is to realize like this:
This medicine is the medicament of being processed by following raw materials by weight proportions:
Cortex Phellodendri 10-25 part Herba Violae 10-25 part Herba Polygoni Avicularis 10-25 part Herba Dianthi 10-25 part
Folium Pyrrosiae 10-35 part Herba Taraxaci 10-35 part Semen Plantaginis 10-35 part Radix Glycyrrhizae 10-20 part.
The weight proportion scope of preparation medicine of the present invention is:
Cortex Phellodendri 10-20 part Herba Violae 10-20 part Herba Polygoni Avicularis 10-20 part Herba Dianthi 10-20 part
Folium Pyrrosiae 10-30 part Herba Taraxaci 10-30 part Semen Plantaginis 10-30 part Radix Glycyrrhizae 10-15 part.
The weight proportion of medicine of the present invention is:
15 parts of 15 portions of Herba Dianthis of 15 parts of Herba Polygoni Avicularis of 15 portions of Herba Violaes of Cortex Phellodendri
10 parts in 20 portions of Radix Glycyrrhizaes of 20 portions of Semen Plantaginiss of 20 parts of Herba Taraxacis of Folium Pyrrosiae.
Above-mentioned each component is processed production of medicine method of the present invention is:
This method for preparing through select materials, clean, dry, grind, sieve, mixing, encapsulated, packing, nine steps of packing accomplish.
Above-mentioned Chinese medicine at first will through selecting materials, clean, process such as drying; When drying, to dry below 60 ℃, grind then, after sieve in dry in the sun under the sun or at low temperature; Reach 100 orders, mix then, encapsulated, packing, pack and promptly accomplished whole process of preparation at last.
When processing this medicine, require to accomplish aseptic in packer's bay and the storeroom, free from dampness.
The present invention has the curative effect height through clinical observation, instant effect, and cure rate is high, taking convenience, advantage such as expense is low.
Function: eliminating damp-heat, Tonglin Hushen.
Cure mainly: urethritis, cystitis and acute and chronic pyelonephritis.
Usage and consumption: oral.A 8-10 grain, 3 times on the one.
The clinical case visual report of medicine of the present invention
This treats urethritis, cystitis, and the medicine Tonglin Hushen capsule of acute and chronic pyelonephritis is a Chinese medicine preparation, this medical instrument has eliminating damp-heat, the effect of Tonglin Hushen.Observe this invention medicines through 290 routine clinical cases and have the curative effect height aspect the urinary tract infection treating the court, and advantage such as have no side effect.
One, case is selected
15-30 year 29 examples among the 125 routine urethritis patients; 31-45 year 33 examples; 46-60 year 36 examples; 61-74 year 27 examples.15-30 year 47 examples among the 165 routine cystitis patients; 31-45 year 39 examples; 46-60 year 41 examples; 61-70 year 38 examples.
Two, diagnosis basis
According to " clinical disease diagnosis is according to curing the improvement standard " diagnosis basis
The urethritis diagnosis basis:
1, acute stage,, urethra had burn feeling, increase the weight of when urinating, so that dysuria.The sense of pruritus or ant row is only arranged when transferring chronic phase to.
2, external orifice of urethra is red and swollen, and purulent secretion is arranged.Along urethra tenderness can be arranged.
3, in the urine red, the leukocyte of volume is arranged.First glass of urine of three-glass test is obviously undesired.
4, urethral secretions smear for microscopic examination can be differentiated with gonococcal urethritis mutually.
5, urethral secretions or prostatic fluid are made PCR inspection pathogen such as gonococcus, mycoplasma, chlamydia etc. to get rid of sexually transmitted disease (STD).
The cystitis diagnosis basis:
(1) acute cystitis
1, burst frequent micturition, urgent micturition and dysurea.Suprapubic region discomfort or pain.Many no General Symptomies.
2, naked eyes terminal hematuria, total hematuria or pyuria.
3, suprapubic region can have tenderness.
4, the urine mirror down inspection red, leukocyte or pus cell are arranged.The urine positive bacterial culture.
(2) chronic cystitis
1, the acute cystitis history of attack is arranged.Slight frequent micturition, urgent micturition and dysurea.
2, routine urianlysis continues to have red, leukocyte.The urine positive bacterial culture.
3, cystoscopy: mucous membrane of urinary bladder is pale, and blood vessel reduces, or has folliculus shape, water pocket shape, granulation shape to change.
4, get biopsy in case of necessity to clarify a diagnosis.
5, the visible bladder edge of cystography is rough, indentation.
Three, cure the improvement standard
Cure the improvement standard according to " clinical disease diagnosis is according to curing the improvement standard "
The urethritis criterion of cure: transference cure, unobstructed micturition, routine urianlysis is normal.The improvement standard: doing well,improving, external orifice of urethra have a small amount of secretions.Routine urianlysis is undesired.
The cystitis criterion of cure:
1, symptom complete obiteration, and do not have outbreak repeatedly.
2, repeatedly routine urianlysis is normal.Continuous 3 urine thin bacterium negative culture results.
The improvement standard:
1, irritation sign of bladder obviously alleviates, but recurrence is arranged.
2, red, the leukopenia of urine.The urine thin born of the same parents cultivate still positive sometimes.
3, cystoscopy: inflammation changes not complete obiteration.
Four, usage and dosage
Oral Tonglin Hushen capsule.A 8-10 grain, one 3 times, one month is a course of treatment.
Five, conclusion analysis
Table 1, oral Tonglin Hushen capsule treatment urethritis 125 examples are observed, and see the following form:
Age Case load Cure Take a turn for the better
15-30 29 22(75.86%) 7(24.14%)
31-45 33 24(72.73%) 9(27.27%)
46-60 36 27(75%) 9(25%)
61-74 27 20(74.07%) 7(25.93%)
Amount to 125 93(74.4%) 32(25.6%)
Can find out that from table 1 this medicine is cured 93 examples, cure rate 74.4% to the treatment urethritis; 32 examples that take a turn for the better, improvement rate 25.6%.
Table 2, oral Tonglin Hushen capsule treatment cystitis 165 examples are observed, and see the following form:
Age Case load Cure Take a turn for the better
15-30 47 37(78.72%) 10(21.28%)
31-45 39 30(76.92%) 9(23.08%)
46-60 41 32(78.05%) 9(21.95%)
61-70 38 28(73.68%) 10(26.32%)
Amount to 165 127(76.97%) 38(23.03%)
From table 2, can find out this medicine to the treatment cystitis cure 127 examples, cure rate 76.97%; 38 examples that take a turn for the better, improvement rate 23.03%.
Description of drawings
Fig. 1 is preparation technology's flow chart of medicine of the present invention.
The specific embodiment
The method for preparing of from Fig. 1, learning this medicine through select materials, clean, dry, grind, sieve, mixing, encapsulated, packing, nine steps of packing accomplish.At first choose raw material 1: 15 kilograms of Cortex Phellodendris, 15 kilograms of Herba Violaes, 15 kilograms of Herba Polygoni Avicularis, 15 kilograms of Herba Dianthis, 20 kilograms of Folium Pyrrosiaes, 20 kilograms of Herba Taraxacis, 20 kilograms of Semen Plantaginiss, 10 kilograms in Radix Glycyrrhizae according to proportioning dosage; Clean set by step, dry, when drying, to dry below 60 ℃ in dry in the sun under the sun or low temperature; And then grind, after sieve, to reach 100 orders; Mix, encapsulated, packing, pack, accomplish whole processing step at last; This medicine is with every dress 0.25g preparation, 100 every bottle.

Claims (5)

1. oral capsule of treating urethritis and cystitis, it is characterized in that: it is processed by following raw materials by weight proportions:
Cortex Phellodendri 10-25 part Herba Violae 10-25 part Herba Polygoni Avicularis 10-25 part Herba Dianthi 10-25 part
Folium Pyrrosiae 10-35 part Herba Taraxaci 10-35 part Semen Plantaginis 10-35 part Radix Glycyrrhizae 10-20 part.
2. a kind of oral capsule of treating urethritis and cystitis according to claim 1 is characterized in that: wherein the weight proportion scope of crude drug is:
Cortex Phellodendri 10-20 part Herba Violae 10-20 part Herba Polygoni Avicularis 10-20 part Herba Dianthi 10-20 part
Folium Pyrrosiae 10-30 part Herba Taraxaci 10-30 part Semen Plantaginis 10-30 part Radix Glycyrrhizae 10-15 part.
3. a kind of oral capsule of treating urethritis and cystitis according to claim 1, it is characterized in that: wherein the weight proportion of crude drug is:
15 parts of 15 portions of Herba Dianthis of 15 parts of Herba Polygoni Avicularis of 15 portions of Herba Violaes of Cortex Phellodendri
10 parts in 20 portions of Radix Glycyrrhizaes of 20 portions of Semen Plantaginiss of 20 parts of Herba Taraxacis of Folium Pyrrosiae.
4. according to claim 1,2 or 3 described a kind of method for preparinies of treating the oral capsule of urethritis and cystitis, it is characterized in that: this method for preparing through select materials, clean, dry, grind, sieve, mixing, encapsulated, packing, nine steps of packing accomplish.
5. a kind of method for preparing of treating the oral capsule of urethritis and cystitis according to claim 4 is characterized in that: choose raw material, cleaning, drying in proportion, when drying, will dry below 60 ℃ in dry in the sun under the sun or at low temperature; Grind then,, reach 100 orders after sieve; Mix then, encapsulated, packing; Pack at last and promptly accomplished whole preparation process, when processing this medicine, require to accomplish aseptic in packer's bay and the storeroom, free from dampness.
CN2008100506075A 2008-04-17 2008-04-17 Oral Tonglin Hushen capsule for curing urethritis, cystitis, acute pyelonephritis and chronic pyelonephritis and preparation method thereof Expired - Fee Related CN101559144B (en)

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CN102253009B (en) * 2011-03-17 2012-08-29 河南科技大学 Detection method of edible fungus specimen preserving liquid
CN108272869B (en) * 2013-09-12 2021-04-06 株洲千金药业股份有限公司 Preparation method of traditional Chinese medicine composition oral liquid preparation for treating lower urinary tract infection
CN103735695A (en) * 2013-12-27 2014-04-23 奉娟 Chinese medicine composition for treating urinary tract infection and preparation method thereof
CN105343615A (en) * 2015-11-29 2016-02-24 刘巍 Medicine for treating chronic pyelonephritis and preparation method

Citations (2)

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CN1404868A (en) * 2002-11-12 2003-03-26 吉林华康药业股份有限公司 Chinese medicinal preparation for treating pyretic stranguria
CN1593477A (en) * 2003-09-11 2005-03-16 谢昌贞 Chinese herbal medicine for treating chronic prostatitis and its preparation

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
CN1404868A (en) * 2002-11-12 2003-03-26 吉林华康药业股份有限公司 Chinese medicinal preparation for treating pyretic stranguria
CN1593477A (en) * 2003-09-11 2005-03-16 谢昌贞 Chinese herbal medicine for treating chronic prostatitis and its preparation

Non-Patent Citations (4)

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Title
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冉军.三金排石汤配合体外震波碎石治疗泌尿系结石78例.《实用中医药杂志》.2005,第21卷(第01期),
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