CN105497111B - Traditional Chinese medicine preparation for promoting lactation and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for promoting lactation and preparation method thereof Download PDFInfo
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Abstract
The invention relates to the field of traditional Chinese medicine health care medicines, in particular to a traditional Chinese medicine preparation for promoting lactation and a preparation method thereof. The traditional Chinese medicine composition with the function of promoting lactation is prepared from the following raw materials in parts by weight: donkey-hide gelatin 0.8-9, astragalus root 3-30, pilose asiabell root 3-30, Chinese angelica root 2-12, Ligusticum wallichii 1-10, kudzu vine root 3-15. The invention also provides a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition has the health-care function of promoting lactation, and has the advantages of stable quality, exact efficacy and high safety.
Description
Technical Field
The invention relates to the field of traditional Chinese medicine health care medicines, in particular to a traditional Chinese medicine preparation for promoting lactation and a preparation method thereof.
Background
The growth and development of the newborn are closely related to the feeding mode, breast milk is the best food and beverage for the infant, contains more than three hundred immune substances which are not contained in any processed food, such as secreted immunoglobulin A, immunoglobulin M, D, G, growth promotion factors, intestinal hormones, active enzymes, large phagocytic cells, lymphocyte B, T and the like, can enhance the immunity of the infant, is rich in nutrition, is suitable for the digestive absorption of the infant, is most beneficial to the growth and development of the infant, can promote the communication of emotion among mothers and mothers by breast feeding, promotes the intelligent development of the infant and is also beneficial to the health of the mother. The milk is sucked by the baby to stimulate the uterine contraction of the mother, reduce the postpartum hemorrhage, inhibit the ovulation, delay the menstruation reoccurrence and reduce the incidence of breast cancer and ovarian cancer. Therefore, the world health organization prescribes that breastfeeding must be performed except for those with clear indications.
The outline of development of children in China (2011) in 2020 specifies that the pure breast-feeding rate of infants in 0-6 months reaches 50 percent. The global strategy for infant feeding, established by the world health organization together with the foundation of children in the united nations, clearly states that infants should be purely breastfed in the first 6 months of life, after which complementary food is added and breastfeeding continues to the age of 2 or above.
National family planning committee data center displays: 39.8% of the women who are born have severe symptoms of no or little milk. In view of the above, there is a need for a safe and effective Chinese medicinal composition with lactation promoting function, which is suitable for most of the puerperae with hypogalactia, and does not affect the physical recovery of the puerperae and the growth and development of the infants.
Disclosure of Invention
In order to solve the problem of hypogalactia of the lying-in woman, the invention aims to provide the traditional Chinese medicine preparation for promoting lactation and the preparation method thereof.
In order to solve the technical problems, the invention adopts the following technical scheme that the traditional Chinese medicine composition with the function of promoting lactation is characterized by being prepared from the following raw materials in parts by weight: 0.8-9 parts of donkey-hide gelatin, 3-30 parts of astragalus, 3-30 parts of codonopsis pilosula, 2-12 parts of angelica, 1-10 parts of ligusticum wallichii and 3-15 parts of kudzu root.
Preferably, the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: donkey-hide gelatin 0.96 parts, astragalus root 4.2 parts, pilose asiabell root 3 parts, Chinese angelica root 3 parts, rhizome of Sichuan lovage 1.8 parts, kudzu vine root 4.2 parts.
The Chinese medicinal composition with lactation promoting effect can also comprise other adjuvants to make into granule; the adjuvants used in the granule include, but are not limited to, one or more of microcrystalline cellulose, starch, dextrin, sucrose, lactose, mannitol, glucose, pregelatinized starch, polyvidone, ethyl cellulose, hydroxypropyl cellulose, and silica gel.
The traditional Chinese medicine considers that milk is generated by blood and depends on qi to move, so that qi and blood are tonified, and lactation is promoted. In the traditional Chinese medicine composition, the donkey-hide gelatin is sweet in taste and neutral in nature, is an emotional product of blood and has a good blood enriching effect; radix astragali and radix Codonopsis greatly reinforce primordial qi; the angelica enriches the blood, has sufficient qi and blood and is active in generating milk; the rhizoma ligustici wallichii is used for promoting qi and activating blood; the kudzu vine root has the effects of ascending the clear, entering the spleen and stomach, promoting blood circulation and removing obstruction in collaterals, and the stomach channel circulates two milk to ensure that qi and blood are transferred to the breast.
The invention also provides a preparation method of the traditional Chinese medicine composition.
A preparation method of a traditional Chinese medicine composition with a function of promoting lactation comprises the following steps:
preparing raw materials: 0.8-9 parts of donkey-hide gelatin, 3-30 parts of astragalus, 3-30 parts of codonopsis pilosula, 2-12 parts of angelica, 1-10 parts of ligusticum wallichii and 3-15 parts of kudzu root; pulverizing colla Corii Asini, sieving with 80 mesh sieve, and weighing; decocting radix astragali, radix Codonopsis, radix Angelicae sinensis, rhizoma Ligustici Chuanxiong, and radix Puerariae in water for 2 times, adding 4-10 times of water each time, decocting for 1.5-2 hr each time, mixing decoctions, filtering, concentrating the filtrate under reduced pressure to obtain soft extract, drying under reduced pressure to obtain dry extract, pulverizing, sieving with 80 mesh sieve, adding colla Corii Asini powder, mixing, and packaging.
Preferably, the preparation method of the traditional Chinese medicine composition comprises the following steps:
preparing raw materials: 0.8-9 parts of donkey-hide gelatin, 3-30 parts of astragalus, 3-30 parts of codonopsis pilosula, 2-12 parts of angelica, 1-10 parts of ligusticum wallichii and 3-15 parts of kudzu root; pulverizing colla Corii Asini, sieving with 80 mesh sieve, and weighing; decocting radix astragali, radix Codonopsis, radix Angelicae sinensis, rhizoma Ligustici Chuanxiong, and radix Puerariae in water for 2 times, adding 8 times of water for 2 hr for the first time, adding 6 times of water for 1.5 hr for the second time, mixing decoctions, filtering, concentrating the filtrate under reduced pressure to obtain soft extract with relative density of 1.30-1.35, drying under reduced pressure to obtain dry extract, pulverizing, sieving with 80 mesh sieve, adding colla Corii Asini powder, mixing, and packaging.
Preferably, the preparation method of the traditional Chinese medicine composition comprises the following steps:
preparing raw materials: 0.8-9 parts of donkey-hide gelatin, 3-30 parts of astragalus, 3-30 parts of codonopsis pilosula, 2-12 parts of angelica, 1-10 parts of ligusticum wallichii, 3-15 parts of kudzu root and other auxiliary materials; pulverizing colla Corii Asini, sieving with 80 mesh sieve, and weighing; decocting radix astragali, radix Codonopsis, radix Angelicae sinensis, rhizoma Ligustici Chuanxiong, and radix Puerariae in water for 2 times, adding 8 times of water for 2 hr for the first time, adding 6 times of water for 1.5 hr for the second time, mixing decoctions, filtering, concentrating the filtrate under reduced pressure to obtain soft extract with relative density of 1.30-1.35, drying under reduced pressure to obtain dry extract, pulverizing, sieving with 80 mesh sieve, adding colla Corii Asini powder, adding appropriate amount of adjuvants, mixing, granulating, drying, grading, mixing, and packaging.
Clinical tests prove that the traditional Chinese medicine composition has the health-care function of promoting lactation, and has the advantages of stable quality, exact efficacy and high safety. The preparation method of the traditional Chinese medicine composition can efficiently produce the traditional Chinese medicine composition with the function of promoting lactation.
Detailed Description
For a further understanding of the present invention, reference will now be made in detail to the following examples.
The inventor carries out a series of experiments to prove that the process is reasonable and feasible, and the quality is stable and controllable, so as to ensure the beneficial effect of the medicament.
1. Investigation of water addition
According to the optimal weight part of the prescription, the following components are taken: mixing 1 part of astragalus root 105g, codonopsis pilosula 75g, angelica 75g, ligusticum wallichii 45g and kudzu root 105g, and weighing 8 parts of samples. Considering that the above medicinal materials and substances related to lactation promotion are all water-soluble, water is preferably used as extraction solvent, and the cream yield is preferably used as index.
Extracting according to the water addition amount of the table 1 (2 hours each time), concentrating and drying to obtain eight dry extracts, wherein the results are shown in the table 2 by taking the yield as an evaluation index.
TABLE 1 Water addition optimization design
| Numbering | The first water adding amount | The second water adding amount |
| 1 | 6 | 6 |
| 2 | 6 | 4 |
| 3 | 8 | 8 |
| 4 | 8 | 6 |
| 5 | 8 | 4 |
| 6 | 10 | 8 |
| 7 | 10 | 6 |
| 8 | 10 | 4 |
Table 2 water addition amount investigation result table
| Sample numbering | Batch (g) | Multiple of water addition | Amount of plaster discharged (g) | Percentage of cream discharged (%) |
| 1 | 405.0 | 6、6 | 126.37 | 31.2 |
| 2 | 405.0 | 6、4 | 118.25 | 29.2 |
| 3 | 405.0 | 8、8 | 134.44 | 33.2 |
| 4 | 405.0 | 8、6 | 142.96 | 35.3 |
| 5 | 405.0 | 8、4 | 137.69 | 34.0 |
| 6 | 405.0 | 10、8 | 144.19 | 35.6 |
| 7 | 405.0 | 10、6 | 143.38 | 35.4 |
| 8 | 405.0 | 10、4 | 142.57 | 35.2 |
The results in Table 2 show that, taking the cream yield as an index, the effective components can be basically extracted by adding 6 to 10 times of water for the first time and 4 to 8 times of water for the second time, and the preferable results are that 8 times of water is added for the first time and 6 times of water is added for the second time, which comprehensively consider various factors.
2. Examination of the decoction time
According to the optimal proportioning weight parts of the prescription, 105g of astragalus, 75g of codonopsis pilosula, 75g of angelica, 45g of ligusticum wallichii and 105g of kudzuvine root are mixed into 1 part, 3 parts of samples are weighed, the samples are decocted for 2 times, 8 times of water is added for the first time, 6 times of water is added for the second time, and the test results are shown in table 3.
TABLE 3 examination of the decoction time
| Sample numbering | First time of decoction | Second decocting time | Amount of plaster discharged (g) | Percentage of cream discharged (%) |
| 1 | 2 | 2 | 143.36 | 35.4 |
| 2 | 2 | 1.5 | 143.16 | 35.3 |
| 3 | 2 | 2.5 | 143.38 | 35.4 |
The results in Table 3 show that the effective components can be extracted basically by using the extraction rate as an index, and by decocting for 2 hours for the first time and 1.5 hours for the second time.
The first embodiment is as follows:
donkey-hide gelatin 80g astragalus root 350g pilose asiabell root 250g
250g of angelica sinensis, 150g of ligusticum wallichii and 350g of kudzu root
Pulverizing colla Corii Asini, sieving with 80 mesh sieve, and weighing; decocting radix astragali, radix Codonopsis, radix Angelicae sinensis, rhizoma Ligustici Chuanxiong, and radix Puerariae in water for 2 times, adding 8 times of water for 2 hr for the first time, adding 6 times of water for 1.5 hr for the second time, mixing decoctions, filtering, concentrating the filtrate under reduced pressure to obtain soft extract with relative density of 1.30-1.35, drying under reduced pressure to obtain dry extract, pulverizing, sieving with 80 mesh sieve, adding colla Corii Asini powder, mixing, and packaging.
Example two:
donkey-hide gelatin 80g astragalus root 350g pilose asiabell root 250g
250g of angelica sinensis, 150g of ligusticum wallichii and 350g of kudzu root
Starch 324g dextrin 80g sucrose 30g
Pulverizing colla Corii Asini, sieving with 80 mesh sieve, and weighing; decocting radix astragali, radix Codonopsis, radix Angelicae sinensis, rhizoma Ligustici Chuanxiong, and radix Puerariae in water for 2 times, adding 8 times of water for 2 hr for the first time, adding 6 times of water for 1.5 hr for the second time, mixing decoctions, filtering, concentrating the filtrate under reduced pressure to obtain soft extract with relative density of 1.30-1.35, drying under reduced pressure to obtain dry extract, pulverizing, sieving with 80 mesh sieve, adding colla Corii Asini powder, adding appropriate amount of adjuvants, mixing, granulating, drying, grading, mixing, and packaging.
The following tests were carried out in order to detect the effect:
the first experimental example: animal experiments
1 Material
1.1 test sample: brown powder or granules. The recommended dosage of the effective components is 6.792g/60 kg.
1.2 Experimental animals: the SPF-level Kunming mouse is female, the weight of the female is 40-60 g, and the experimental environment is a barrier environment.
2 method of experiment
An overload lactation model method is adopted, and a negative blank control group and 3 test sample groups are set. The dose was set to 0.566g/kg · bw, 1.132g/kg · bw, 3.396g/kg · bw, corresponding to 5 times, 10 times, 30 times the recommended intake of the human body, respectively. Preparing a test substance by using distilled water; the placebo group was gavaged with water.
And (3) delivering after the pregnant mice are adaptively fed for 3-4 days, randomly dividing the pregnant mice into a blank control group and 5, 10 and 30 times dosage groups according to the nest of the pregnant mice and the weight of born newborn mice, wherein each group comprises 10 female mice, each female mouse carries 10 newborn mice, and each female mouse and the newborn mice are fed in a single cage. The corresponding dose of the test substance was gavaged starting from the birth day 1 of the female mice for 21 days continuously, and the lactation amount of each female mouse, the birth weight of the newborn mouse, and the body weight at the 7 th, 14 th, and 21 th days after birth were observed and measured regularly every day.
Lactation determination (weighing): weighing the mother mouse and the baby mouse respectively 8 days earlier, isolating the mother mouse and the baby mouse for 6h, combining the two mice to nurse for 1h, weighing the weight of the baby mouse before and after lactation, and representing the lactation amount of the mother mouse by the difference between the two weights.
3 results of the experiment
3.1 Effect on the lactation yield of the mother mouse
And (3) counting the average lactation amount of each group of the female mice from the 2 nd day to the 14 th day, and calculating the accumulated lactation amount of each group of the female mice from 2 d to 7d, 2 d to 10d and 2 d to 14d, wherein the results are shown in tables 4 and 5. Compared with the control group, the 10-fold and 30-fold dosage groups can obviously or very obviously increase the milk secretion of the female mice on the 10 th day (P is less than 0.05, and P is less than 0.01); the 3 dosage groups can obviously or very obviously increase the accumulated lactation amount (P is less than 0.05, and P is less than 0.01) of the female mice on the 2 nd to 10 th days and the 2 nd to 14 th days.
TABLE 4 lactation volume (+ -s) (unit: g) at different times for each group of dams during the experiment
| Group of | Number of animals | Day 2 | Day 7 | Day 10 | Day 14 |
| Control group | 10 | 0.20±0.24 | 0.98±0.36 | 0.52±0.35 | 0.76±0.56 |
| 5 times dose group | 10 | 0.23±0.20 | 1.27±0.82 | 0.98±0.62 | 1.02±0.58 |
| 10 times dosage group | 10 | 0.27±0.26 | 1.35±0.47 | 1.12±0.48(1) | 0.79±0.51 |
| 30 times dosage group | 10 | 0.22±0.20 | 1.30±0.79 | 1.17±0.58(2) | 1.20±0.51 |
Note: (1) compared with a control group, P is less than 0.05; (2) p is less than 0.01 compared with the control group.
TABLE 5 cumulative lactation (+ -s) (unit: g) of groups of dams during the experiment
| Group of | Number of animals | 2-7 d integration | 2-10 d total | 2-14 d integration |
| Control group | 10 | 3.50±1.41 | 5.77±2.31 | 8.99±3.82 |
| 5 times dose group | 10 | 5.08±2.04 | 8.14±2.43(1) | 12.94±3.12(1) |
| 10 times dosage group | 10 | 4.72±1.00 | 8.82±1.68(2) | 12.69±2.37(1) |
| 30 times dosage group | 10 | 5.03±2.62 | 8.91±2.86(2) | 13.92±3.41(2) |
Note: (1) compared with a control group, P is less than 0.05; (2) p is less than 0.01 compared with the control group.
3.2 Effect on weight growth in newborn mice
After the birth weight, the weights at 7 th day, 14 th day and 21 st day of newborn mice of each experimental group are subjected to homogeneity of variance test, the birth weight, the weights at 7 th day, 14 th day and 21 st day of newborn mice of each experimental group meet the requirement of homogeneity of variance, and statistical treatment is carried out by a single-factor variance analysis method and a pairwise comparison method of mean values between a plurality of experimental groups and a control group. The results in Table 6 show that there was no significant difference in birth weight (P > 0.05) among the groups of pups, i.e., the weight distribution among the groups of pups was uniform before the experiment. The weight of the mice in the 10-time dose group at day 7 is obviously higher than that of the control group (P < 0.01), the weight of the mice in the 5-time dose group at day 14 and day 21 is also obviously higher than that of the control group (P < 0.01), and the weight of the mice in the 30-time dose group is increased compared with that of the control group, but the difference is not obvious (P > 0.05).
TABLE 6 lactation weight changes (. + -. s) (unit: g) for groups of pups
Note: (1) p is less than 0.01 in comparison with the control group
4 conclusion
The animal experiment result shows that compared with a blank control group, the traditional Chinese medicine composition with different dosages can obviously and extremely improve the milk secretion or the accumulated milk secretion of the female rat (P is less than 0.05, and P is less than 0.01), the 5-time dosage can obviously increase the body weight of the newborn rat on the 14 th day and the 21 th day (P is less than 0.01), and the 10-time dosage can obviously increase the body weight of the newborn rat on the 7 th day (P is less than 0.01), which indicates that the traditional Chinese medicine composition can increase the milk secretion of the female rat and promote the body weight of the newborn rat to increase.
Experiment example two: clinical experiments
1. Materials and methods
1.1 test sample: brown powder or granules. The recommended dose of the effective components of the human body is 6.792g/60kg per day.
1.2 tasting population: according to the voluntary principle, the following criteria are selected.
1.2.1 test feeders inclusion criteria: the age of mother is less than or equal to 35 years old; degree of culture above high school; initial production; single tire; the mother and the child are healthy; the breast swelling degree is less than or equal to 1; the milk quantity is insufficient, and the infants eat the milk; the economic status of the family of the puerpera is good, and the normal diet needs of the puerpera can be met.
1.2.2 test taker exclusion criteria: mother or baby is weak and sick; postpartum hemorrhage; those who are allergic to the ingredients of the product; abnormal breast development of mother; patients with breast diseases; poor taste: people who are accustomed to smoking, drinking, etc.; other lactation promoting medicines or delactation medicines are taken.
1.3 experimental design and grouping: 120 hypogalactia women were equally divided into control and feeding groups of 60, and the control group was blank without any form of sample or placebo.
1.4 Observation index
1.4.1 general case: observing mental status, defecation status, diet status, sleep status, whether other adverse reactions exist, and the like.
1.4.2 safety observations: blood routine and urine routine indexes; conventional blood biochemical indexes; an electrocardiogram. The index of the test person is tested 1 time before and after the test, and the index of the control group is tested 1 time before the test.
1.4.3 Observation of efficacy
General conditions are as follows: mental status, eating status, sleeping status, defecation status, etc.
Breast distension degree: breast turgor was observed daily according to the following grading scale and breast turgor scores were recorded. The integral of the period (15d) during which the test substance is administered is accumulated. The integration and efficiency of the test group and the control group were compared.
A, mammary swelling, pain and milk overflow, 2 points.
B, slight breast swelling, slight pain on touch, no milk overflow but milk ejection by hand, 1 minute.
C, no expansion of breast, no pain on touch, no milk squeezed by hand or no milk drop, 0 point.
The method has the following advantages: breast distension is not less than 15 minutes, and is ineffective: the breast swelling degree is less than 15 minutes.
And (3) determining the milk secretion: milk is expressed from one breast 2h after the last lactation of the baby until no milk is expressed from the hands, and the milk yield is measured.
Determination of protein content in milk: at the end of the test, a measurement of the protein content of the milk was carried out.
1.5 safety criteria
1.5.1 evaluation of effectiveness: the breast swelling degree and the milk secretion amount have statistical significance, and the test object can be judged to have the effect of promoting milk secretion.
1.5.2 safety assessment: each safety index should not result in harm to human health and adverse reaction related to the test sample.
2 results
2.1 general case
In the test process, 60 cases of the test group have 1 missed visit, 60 cases of the control group have 2 missed visits, and the total missed visit rate is 2.5 percent. After the testers eat the samples for 15 days, the general condition of the mothers is good, the infants develop normally, and no adverse reaction occurs.
2.2 Effect on Breast distension
TABLE 7 Effect on Breast distension integral (. + -. s)
Note: (1) p is less than 0.01
As can be seen from Table 7, the variance of the original data is uneven, statistical treatment is carried out by using t' test, the total integral of the breast distension 15d is compared between the control group and the test food group, the difference is extremely significant (P is less than 0.01), and the traditional Chinese medicine composition can increase the integral of the breast distension.
2.3 Effect on lactation volume
TABLE 8 Effect on lactation (+ -s) (unit: ml)
Note: (1) p is less than 0.01
As can be seen from Table 8, the original data has different variances, and the statistical treatment is carried out by using the t' test, so that the increase value of the milk secretion is compared between the control group and the test group, and the difference has great significance (P is less than 0.01), namely the traditional Chinese medicine composition can increase the milk secretion.
2.4 Effect on the protein content of milk
TABLE 9 Effect on protein content in milk (+ -s) (unit: g/100g)
As can be seen from Table 9, the original data was subjected to the uniform variance test, which met the requirements of uniform variance, and the statistical treatment was performed by t-test, so that the comparative difference between the milk protein content after the feeding trial and the milk protein content between the control group and the feeding trial group was not significant (P > 0.05), i.e., the traditional Chinese medicine composition of the present invention had no effect on the milk protein content.
2.5 safety index observations before and after eating trials
2.5.1 blood, urine routine and blood Biochemical index
As can be seen from Table 10, the conventional and biochemical blood and blood test indexes of the two groups of people before the test are within the normal range, and the test indexes of the test eater are within the normal range after the test eating group eats a certain oral liquid for 15 days.
TABLE 10 before and after meal test, general index of blood, urine and biochemical index of blood (+ -s)
2.5.2 Electrocardiogram
The electrocardiogram results of 120 subjects in the first half of the test are all normal.
3 conclusion
The breast distension reflects the level of milk storage after a certain lactation interval and can therefore be used as an indirect observation indicator of lactation yield. The indicator of the protein content of the milk reflects whether the increased lactation is caused by the increased water content in the milk. In the test food observation, after the test food group eats the traditional Chinese medicine composition for 15 days, the experimental result shows that the breast swelling degree and the lactation amount can be increased. Compared with the control group, the content of the milk protein is not influenced. Therefore, the traditional Chinese medicine composition has certain function of promoting milk secretion. Through eating observation of the test taker 15d, no adverse reaction is subjectively caused, and no damage to the human body is found in objective physical examination and assay examination, so that the oral liquid is proved to be harmless to the human health under the experimental conditions.
The above description of the embodiments is only intended to facilitate the understanding of the method and the core idea of the present invention. It should be noted that, for those skilled in the art, it is possible to make various improvements and modifications to the present invention without departing from the principle of the present invention, and those improvements and modifications also fall within the scope of the claims of the present invention.
Claims (6)
1. A traditional Chinese medicine composition with a lactation promoting effect is characterized by being prepared from the following raw material medicines in parts by weight: 0.8-9 parts of donkey-hide gelatin, 3-30 parts of astragalus, 3-30 parts of codonopsis pilosula, 2-12 parts of angelica, 1-10 parts of ligusticum wallichii and 3-15 parts of kudzu root.
2. The traditional Chinese medicine composition with the lactation promoting effect according to claim 1, which is prepared from the following raw material medicines in parts by weight: donkey-hide gelatin 0.96 parts, astragalus root 4.2 parts, pilose asiabell root 3 parts, Chinese angelica root 3 parts, rhizome of Sichuan lovage 1.8 parts, kudzu vine root 4.2 parts.
3. The traditional Chinese medicine composition with lactation promoting effect according to claim 1 or 2, which is characterized in that: other adjuvants can also be added to make into granule.
4. A method for preparing the traditional Chinese medicine composition with lactation promoting effect of claim 1 or 2, which is characterized in that: weighing the components according to the formula amount, mixing the components completely, taking the donkey-hide gelatin, crushing, sieving with a 80-mesh sieve, and weighing for later use; decocting radix astragali, radix Codonopsis, radix Angelicae sinensis, rhizoma Ligustici Chuanxiong, and radix Puerariae in water for 2 times, adding 4-10 times of water each time, decocting for 1.5-2 hr each time, mixing decoctions, filtering, concentrating the filtrate under reduced pressure to obtain soft extract, drying under reduced pressure to obtain dry extract, pulverizing, sieving with 80 mesh sieve, adding colla Corii Asini powder, mixing, and packaging.
5. The preparation method of the traditional Chinese medicine composition with lactation promoting effect according to claim 4, is characterized in that: weighing the components according to the formula amount, mixing the components completely, taking the donkey-hide gelatin, crushing, sieving with a 80-mesh sieve, and weighing for later use; decocting radix astragali, radix Codonopsis, radix Angelicae sinensis, rhizoma Ligustici Chuanxiong, and radix Puerariae in water for 2 times, adding 8 times of water for 2 hr for the first time, adding 6 times of water for 1.5 hr for the second time, mixing decoctions, filtering, concentrating the filtrate under reduced pressure to obtain soft extract with relative density of 1.30-1.35, drying under reduced pressure to obtain dry extract, pulverizing, sieving with 80 mesh sieve, adding colla Corii Asini powder, mixing, and packaging.
6. A method for preparing the traditional Chinese medicine composition with the function of promoting lactation, which is characterized by comprising the following steps: weighing the components according to the formula amount, mixing the components completely, taking the donkey-hide gelatin, crushing, sieving with a 80-mesh sieve, and weighing for later use; decocting radix astragali, radix Codonopsis, radix Angelicae sinensis, rhizoma Ligustici Chuanxiong, and radix Puerariae in water for 2 times, adding 8 times of water for 2 hr for the first time, adding 6 times of water for 1.5 hr for the second time, mixing decoctions, filtering, concentrating the filtrate under reduced pressure to obtain soft extract with relative density of 1.30-1.35, drying under reduced pressure to obtain dry extract, pulverizing, sieving with 80 mesh sieve, adding colla Corii Asini powder, adding appropriate amount of adjuvants, mixing, granulating, drying, grading, mixing, and packaging.
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