CN102847073A - Medicine for promoting discharging of urinary calculus - Google Patents

Abstract

The invention relates to a medicine for promoting discharging of urinary calculus. The medicine for promoting discharging of urinary calculus is prepared by traditional Chinese medicines and prepared by the following steps: selecting and evenly mixing lysimachia christinae hance, lygodium japonicum, endothelium corneum gigeriae galli, magnesium silicate, semen plantaginis, dandelion, radix paeoniae rubra, curcuma zedoary, scirpus fluviatilis, flower carthami, the root of bidentate achyranthes, polygonum aviculare and dianthus superbus which are washed by clean water, smashing the mixture into medicine powder of 100-120 meshes, and sterilizing and disinfecting the powder to prepare capsule products in a conventional method. The medicine for promoting discharging of urinary calculus is good in removing urinary calculus of urinary calculus patients adopting external lithontriptic treatment and fast in treating effect, greatly shortens urinary calculus discharging time of patients and improves curing rate.

Description

A kind of medicine that promotes that urinary system calculus is discharged

Technical field

The present invention relates to a kind of medicine that promotes that urinary system calculus is discharged, relate in particular to a kind of medicine of promotion urinary system calculus discharge of the preparation take Chinese medicine as crude drug.

Background technology

Urinary system calculus is called for short urinary calculi, is a kind of commonly encountered diseases, refers at urinary system endogenous cause of ill urine concentrating and precipitating and forms granule or in bulk sample aggregation, comprises renal calculus, ureteral calculus, vesical calculus and lithangiuria.The urinary system calculus main manifestations is: 1. renal colic history is in various degree arranged, and with lower abdominal distention pain, hematuria or discontinuity hematuria; 2. can be with in the symptoms such as frequent micturition, urgent micturition, dysurea one or more.This patient onset is anxious, hurt like hell, if calculus in vivo long-term existence arrange not go out externally, cause the long-term hydrops of kidney, can cause the impaired renal function wound, even increase the weight of state of an illness threat to life, bring very big misery and financial burden to patient and family members.

Using extracorporeal lithotiptor is one of common method of urinary system calculus treatment, the method has been avoided the shortcoming of medicine and operative treatment, need not be in hospital, to the human zero damage, do not affect Working Life, but after the treatment, often need patient's Natural excrement rubble, because people's individual variation, natural lithagogue effect are not bery desirable.

Summary of the invention

The purpose of this invention is to provide a kind ofly have no side effect, lithagogue effect significantly promotes the medicine that urinary system calculus is discharged, solve use the extracorporeal lithotiptor treatment after, the calculus efflux time is long, halfway problem.

Medicine of the present invention is that the Chinese medicine by following parts by weight is that crude drug prepares:

Herba Lysimachiae 6～14, Spora Lygodii 2～8 Endothelium Corneum Gigeriae Galli 2～8 Talcums 2～8

Semen Plantaginis 2～8 Herba Taraxacis 2～8 Radix Paeoniae Rubra 1～6 Rhizoma Curcumae 2～8

Rhizoma sparganic 2～8 Flos Carthamis 1～6 Radix Achyranthis Bidentatae 2～8 Herba Polygoni Avicularis 2～8

Herba Dianthi 2～8.

Preferably, medicine of the present invention is that the Chinese medicine by following parts by weight is that crude drug prepares:

Herba Lysimachiae 8～12, Spora Lygodii 4～6 Endothelium Corneum Gigeriae Galli 4～6 Talcums 4～6

Semen Plantaginis 4～6 Herba Taraxacis 4～6 Radix Paeoniae Rubra 2～5 Rhizoma Curcumae 4～6

Rhizoma sparganic 4～6 Flos Carthamis 2～5 Radix Achyranthis Bidentataes 4～6 Herba Polygoni Avicularis 4～6

Herba Dianthi 4～6.

The medicine of above-mentioned each component can be made said peroral dosage form on any pharmaceuticss such as tablet, pill, powder, capsule, and the preferred dosage form of the present invention is capsule.

The concrete preparation method of medicine capsule of the present invention is: said medicine by described parts by weight mix homogeneously, is ground into 100～120 purpose medicated powder, and the sterilization dress makes the capsule product according to a conventional method.

The traditional Chinese medical science thinks and suffers from a deficiency of the kidney and damp-heat in the urinary bladder is the basic reason that urinary system calculus forms, and sandstone forms and further causes kidney, ureter, the local qi depression to blood stasis of bladder, the very bright network of heat, the absurd row of forcing blood and see hematuria.Stone amasss the duty of then involving kidney department urine in upper, and pent-up must not be let out down, stagnation of QI-blood, and stagnation of QI and blood may bring about pain, stone amass in downside bladder qi dysfunction, dysuria.The Therapeutic Principle answers clearing away heat-damp and promoting diuresis, and Tonglin Paishi is main, blood circulation promoting and blood stasis dispelling, and it is auxiliary augmenting kidney unit.In this prescription, the Herba Lysimachiae relieving stranguria by diuresis, lithagogue effect is remarkable; The Spora Lygodii eliminating damp-heat, only urethra pain is arrogated to oneself in treating stranguria pain relieving especially; The blood stasis dispelling of Endothelium Corneum Gigeriae Galli Sal Nitri is strengthened Herba Lysimachiae, the Spora Lygodii lithagogue effect; Herba Taraxaci, Talcum, the heat clearing away of Semen Plantaginis ， Herba Polygoni Avicularis, inducing diuresis for treating stranguria syndrome, calculus; Radix Paeoniae Rubra, Rhizoma Sparganii, Rhizoma Curcumae, the Flos Carthami blood circulation promoting and blood stasis dispelling, merit is amassed pain relieving, thereby strengthens the merit of Tonglin Paishi; The Radix Achyranthis Bidentatae promoting blood circulation to remove obstruction in the collateral, the guiding calculus is descending; The Herba Dianthi inducing diuresis for treating stranguria syndrome, removing blood stasis stimulates the menstrual flow.All medicines share, and play altogether heat clearing away, promoting urination and stopping pain, and the merit of calculus, effective to the discharge that promotes urinary system calculus, have no side effect.

Be that further investigation medicine of the present invention promotes the clinical efficacy that urinary system calculus is discharged, the Patients with Urinary Stone of selecting 96 routine preparations to carry out external stone crushing has carried out clinical observation on the therapeutic effect.

1, clinical data

96 routine Patients with Urinary Stones, it all is clinic case, male 57 examples wherein, women 39 examples, minimum 15 years old of age, maximum 63 years old, all cases all detect through B ultrasonic and abdominal X-ray and are diagnosed as urinary system calculus and prepare to carry out the external stone crushing treatment, renal calculus 44 examples wherein, ureteral calculus 51 examples, the minimum 0.3x0.3CM of ultrasound diagnosis calculus, maximum 0.9x0.8CM.

96 routine Patients with Urinary Stones are divided into treatment group and matched group, treatment group 50 people, matched group 46 people.

2, Therapeutic Method

Treatment group is oral capsule medicine of the present invention after the extracorporeal lithotiptor treatment, every day 4 times, each 4;

Matched group is taken conventional anti-inflammation drugs after the extracorporeal lithotiptor treatment.

3, criterion of therapeutical effect

Diagnostic criteria with reference to " modern difficult treatment Chinese traditional medical diagnose is learned " is drafted:

Recovery from illness: subjective symptoms and sign disappear, and calculus is discharged fully, and x-ray or ultrasound diagnosis urinary system are without calculus sound shadow picture;

Effectively: subjective symptoms and sign are obviously improved, and multiple calculus is discharged, and x-ray or ultrasound diagnosis urinary system calculus dwindle or the calculus position moves down more than the 2CM;

Invalid: sings and symptoms is without significant change, and x-ray or ultrasound diagnosis urinary system calculus are without obviously dwindling or the position moves down.

4, therapeutic outcome

The curative effect comparative result sees Table 1 after two groups of case treatments;

Curative effect relatively after the table 1 liang group case treatment.

Group	The example number	Recovery from illness n(%)	Effective n(%)	Invalid n(%)	Total effective rate n(%)
						Matched group	46	37（80.4）	4（8.7）	5（10.9）	41（89.1）
Treatment group	50	45（90）	3（6）	2（4）	45（96）

5, carry out the calculus time relatively for two groups of recovery from illness cases;

37 example recovery from illness patients in the matched group drain 50 days average times of rubble, the shortest 25 days, the longest 90 days;

45 example recovery from illness patients in the treatment group drain 15 days average times of rubble, the shortest 10 days, the longest 35 days.

Clinical observation on the therapeutic effect result demonstration, medicine of the present invention is discharged effective, rapid-action to the rubble of the Patients with Urinary Stone of use external stone crushing treatment, shortened greatly patient's the calculus time, has improved cure rate.

Concrete case:

Zhang, the man 35 years old, suffers from proximal ureteral calculus, stomachache, nausea and vomiting.B ultrasonic shows right hydronephrosis, the right side proximal ureteral calculus, and calculus is the 0.8x0.4CM size approximately.Behind the extracorporeal lithotiptor rubble, take one week of capsule of the present invention, cooperating does more physical exercises drinks water more, and B ultrasonic is checked right kidney without hydrops after ten days, and ureter has no calculus.

Lee so-and-so, the woman 28 years old, suffers from distal ureteral calculi, stomachache, nausea and vomiting.B ultrasonic shows left hydronephrosis, the left side distal ureteral calculi, and calculus is the 0.6x0.3CM size approximately.Behind the extracorporeal lithotiptor rubble, take one week of capsule of the present invention, cooperating does more physical exercises drinks water more, and B ultrasonic is checked left kidney without hydrops after seven days, and ureter has no calculus.

Zhang, the man, 53 years old, suffer from defeated right renal calculus, ache in the kidney district.B ultrasonic shows right renal calculus, and calculus is the 0.5x0.4CM size approximately.Behind the extracorporeal lithotiptor rubble, take two weeks of capsule of the present invention, cooperating does more physical exercises drinks water more, and B ultrasonic is checked right renal calculus and is discharged behind the fortnight, and ureter has no calculus.

The specific embodiment

Embodiment 1

Get Herba Lysimachiae 60g, Spora Lygodii 20g, Endothelium Corneum Gigeriae Galli 20g, Talcum 20g, Semen Plantaginis 20g, Herba Taraxaci 20g, Radix Paeoniae Rubra 10g, Rhizoma Curcumae 20g, rhizoma sparganic 20g, Flos Carthami 10g, Radix Achyranthis Bidentatae 20g, Herba Polygoni Avicularis 20g, Herba Dianthi 20g mix homogeneously selected, that clear water is cleaned, be ground into 100～120 medicated powder, sterilization makes the capsule product according to a conventional method.

Embodiment 2

Get Herba Lysimachiae 140g, Spora Lygodii 80g, Endothelium Corneum Gigeriae Galli 80g, Talcum 80g, Semen Plantaginis 80g, Herba Taraxaci 80g, Radix Paeoniae Rubra 60g, Rhizoma Curcumae 80g, rhizoma sparganic 80g, Flos Carthami 60g, Radix Achyranthis Bidentatae 80g, Herba Polygoni Avicularis 80g, Herba Dianthi 80g mix homogeneously selected, that clear water is cleaned, be ground into 100～120 medicated powder, sterilization makes the capsule product according to a conventional method.

Embodiment 3

Get Herba Lysimachiae 80g, Spora Lygodii 40g, Endothelium Corneum Gigeriae Galli 40g, Talcum 40g, Semen Plantaginis 40g, Herba Taraxaci 40g, Radix Paeoniae Rubra 20g, Rhizoma Curcumae 40g, rhizoma sparganic 40g, Flos Carthami 20g, Radix Achyranthis Bidentatae 40g, Herba Polygoni Avicularis 40g, Herba Dianthi 40g mix homogeneously selected, that clear water is cleaned, be ground into 100～120 medicated powder, sterilization makes the capsule product according to a conventional method.

Embodiment 4

Get Herba Lysimachiae 120g, Spora Lygodii 60g, Endothelium Corneum Gigeriae Galli 60g, Talcum 60g, Semen Plantaginis 60g, Herba Taraxaci 60g, Radix Paeoniae Rubra 50g, Rhizoma Curcumae 60g, rhizoma sparganic 60g, Flos Carthami 50g, Radix Achyranthis Bidentatae 60g, Herba Polygoni Avicularis 60g, Herba Dianthi 60g mix homogeneously selected, that clear water is cleaned, be ground into 100～120 medicated powder, sterilization makes the capsule product according to a conventional method.

Claims (2)

1. medicine that promotes that urinary system calculus is discharged is that the Chinese medicine by following parts by weight is that crude drug prepares:

Herba Lysimachiae 6～14, Spora Lygodii 2～8 Endothelium Corneum Gigeriae Galli 2～8 Talcums 2～8

Semen Plantaginis 2～8 Herba Taraxacis 2～8 Radix Paeoniae Rubra 1～6 Rhizoma Curcumae 2～8

Rhizoma sparganic 2～8 Flos Carthamis 1～6 Radix Achyranthis Bidentatae 2～8 Herba Polygoni Avicularis 2～8

Herba Dianthi 2～8.

2. the promotion urinary system calculus according to claim 1 medicine of discharging is that the Chinese medicine by following parts by weight is that crude drug prepares:

Herba Lysimachiae 8～12, Spora Lygodii 4～6 Endothelium Corneum Gigeriae Galli 4～6 Talcums 4～6

Semen Plantaginis 4～6 Herba Taraxacis 4～6 Radix Paeoniae Rubra 2～5 Rhizoma Curcumae 4～6

Rhizoma sparganic 4～6 Flos Carthamis 2～5 Radix Achyranthis Bidentataes 4～6 Herba Polygoni Avicularis 4～6

Herba Dianthi 4～6.