CN101537216B - Safe infusion apparatus and preparation method thereof - Google Patents
Safe infusion apparatus and preparation method thereof Download PDFInfo
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- CN101537216B CN101537216B CN2009100668534A CN200910066853A CN101537216B CN 101537216 B CN101537216 B CN 101537216B CN 2009100668534 A CN2009100668534 A CN 2009100668534A CN 200910066853 A CN200910066853 A CN 200910066853A CN 101537216 B CN101537216 B CN 101537216B
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- 238000001802 infusion Methods 0.000 title claims abstract description 18
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- 239000010410 layer Substances 0.000 claims abstract description 107
- 239000004800 polyvinyl chloride Substances 0.000 claims abstract description 75
- 229920000915 polyvinyl chloride Polymers 0.000 claims abstract description 75
- 229920002635 polyurethane Polymers 0.000 claims abstract description 61
- 239000004814 polyurethane Substances 0.000 claims abstract description 61
- 239000002131 composite material Substances 0.000 claims abstract description 48
- 239000002344 surface layer Substances 0.000 claims abstract description 10
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims description 46
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 claims description 42
- 238000000071 blow moulding Methods 0.000 claims description 18
- 230000006835 compression Effects 0.000 claims description 16
- 238000007906 compression Methods 0.000 claims description 16
- 238000007664 blowing Methods 0.000 claims description 14
- 229910000831 Steel Inorganic materials 0.000 claims description 8
- 239000010959 steel Substances 0.000 claims description 8
- 230000001070 adhesive effect Effects 0.000 claims description 5
- 150000001875 compounds Chemical class 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 5
- 239000000853 adhesive Substances 0.000 claims description 4
- 239000012530 fluid Substances 0.000 claims description 4
- 238000001990 intravenous administration Methods 0.000 claims description 4
- 230000001105 regulatory effect Effects 0.000 claims description 4
- 239000002904 solvent Substances 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 229920002725 thermoplastic elastomer Polymers 0.000 claims description 3
- 239000003814 drug Substances 0.000 abstract description 9
- 239000004014 plasticizer Substances 0.000 abstract description 6
- 239000007788 liquid Substances 0.000 abstract description 5
- 239000002994 raw material Substances 0.000 abstract description 2
- 230000010412 perfusion Effects 0.000 abstract 4
- 230000007547 defect Effects 0.000 abstract 1
- 238000001125 extrusion Methods 0.000 abstract 1
- 238000010101 extrusion blow moulding Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 description 26
- BZHJMEDXRYGGRV-UHFFFAOYSA-N Vinyl chloride Chemical compound ClC=C BZHJMEDXRYGGRV-UHFFFAOYSA-N 0.000 description 7
- 238000012545 processing Methods 0.000 description 5
- 229940079593 drug Drugs 0.000 description 4
- 239000012760 heat stabilizer Substances 0.000 description 4
- 238000005303 weighing Methods 0.000 description 4
- 230000001627 detrimental effect Effects 0.000 description 3
- 239000000178 monomer Substances 0.000 description 3
- 239000004803 Di-2ethylhexylphthalate Substances 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- BJQHLKABXJIVAM-UHFFFAOYSA-N bis(2-ethylhexyl) phthalate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1C(=O)OCC(CC)CCCC BJQHLKABXJIVAM-UHFFFAOYSA-N 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 229910000041 hydrogen chloride Inorganic materials 0.000 description 2
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 description 2
- 238000005457 optimization Methods 0.000 description 2
- XNGIFLGASWRNHJ-UHFFFAOYSA-N phthalic acid Chemical compound OC(=O)C1=CC=CC=C1C(O)=O XNGIFLGASWRNHJ-UHFFFAOYSA-N 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 229910052788 barium Inorganic materials 0.000 description 1
- DSAJWYNOEDNPEQ-UHFFFAOYSA-N barium atom Chemical compound [Ba] DSAJWYNOEDNPEQ-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000711 cancerogenic effect Effects 0.000 description 1
- 231100000357 carcinogen Toxicity 0.000 description 1
- 239000003183 carcinogenic agent Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000000593 degrading effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000002991 molded plastic Substances 0.000 description 1
- WQDGUYZIAJKLAB-UHFFFAOYSA-N octan-2-yl nitrite Chemical compound CCCCCCC(C)ON=O WQDGUYZIAJKLAB-UHFFFAOYSA-N 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 239000002341 toxic gas Substances 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
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- B29C47/92—
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- Materials For Medical Uses (AREA)
- Extrusion Moulding Of Plastics Or The Like (AREA)
- Laminated Bodies (AREA)
Abstract
The invention provides a safe infusion apparatus and a preparation method thereof. The infusion apparatus comprises a dropping funnel and a perfusion tube; wherein, both the dropping funnel and the perfusion tube are made of polyurethane/ polyvinyl chloride double-layer composite material; the inner surface layer of the dropping funnel made of the polyurethane/ polyvinyl chloride double-layer composite material is a polyurethane layer, and the outer surface layer thereof is a polyvinyl chloride layer. The polyurethane/ polyvinyl chloride double-layer composite material is prepared by a co-extrusion blow molding method, and the perfusion tube made of the polyurethane/ polyvinyl chloride double-layer composite material is prepared by a co-extrusion method. The safe infusion apparatus can avoid the defect that the polyvinyl chloride perfusion tube absorbs micromolecules such as medicine, plasticizer and the like to pollute liquid medicine, and has the advantages of excellent mechanical property, easy bonding and assembling as well as low raw material cost.
Description
Technical field
The present invention relates to a kind of medical apparatus and instruments, be specifically related to a kind of safe infusion apparatus and preparation method.
Background technology
The polrvinyl chloride low price, high comprehensive performance generally is used to make disposable transfusion device.Along with clinical practice extensively and profoundly with the relevant medical science and technology development, it is found that there is potential safety hazard in pvc material itself, processing and serviceability on also have many defectives.Corvic can produce a spot of Vinyl Chloride Monomer in producing or processing, this chemical compound has been proved to be carcinogen.In order to obtain the soft PVC goods, must use plasticizer in the processing, wherein, (DEHP) use of plasticizer is maximum for phthalic acid two (2-Octyl Nitrite), and this class plasticizer can enter medicinal liquid, and enters human body thereupon, is detrimental to health.For preventing that polrvinyl chloride from degrading in the course of processing, the chemical compound that adds elements such as leaded, zinc and barium is usually made heat stabilizer, and in use, the heavy metal in these heat stabilizers may enter human body.The waste treatment difficulty of polrvinyl chloride medical disposable material is buried for a long time and is not degraded, and burns then to produce hydrogen chloride with toxic gas such as bioxin, contaminated environment.Polrvinyl chloride adds can decompose the generation hydrogen chloride gas man-hour, not only corrosion processing equipment, and threat operator ' s health.
Residual Vinyl Chloride Monomer, the DEHP plasticizer and the heat stabilizer of interpolation are not to be chemically bonded on the polrvinyl chloride molecule in the pvc material, the polrvinyl chloride transfusion device in use, these micromolecule can enter medicinal liquid by modes such as diffusion, extractions, and then enter human body, are detrimental to health.In addition, because polrvinyl chloride is a polar material, the polrvinyl chloride transfusion device of preparation has strong adsorption to the part medicine, directly causes curative effect of medication to descend, and not only wastes medicine, also can make drug dose inaccurate, incurs loss through delay the patients ' recovery time.
In view of the problem of pvc material and transfusion device existence thereof, the new material that all on the research and development price, can contend with both at home and abroad, performance satisfies the transfusion device instructions for use with polrvinyl chloride.
China's utility model patent 200420052781.0 discloses a kind of non-PVC transfusion device; China's utility model patent 200720029591.0 discloses a kind of disposable use TPO transfusion device; Chinese invention patent 200510014749.2 discloses a kind of radiation modified polyolefinic thermoplastic elastomer blending resin, and this resin can be used for replacing the PVC material that traditional disposable transfusion device adopts.
So far, there are many deficiencies in non-PVC transfusion device material and the transfusion device thereof developed, can reduce:
Phenomenons such as pipeline entanglement can appear in (1) non-PVC transfusion device surfaces of tacky in preservation or use.
(2) mechanical property of non-PVC transfusion material is relatively poor, and the transfusion device pipeline of preparation is in stressed easy deformation or fracture down.
(3) adhesive property of non-PVC transfusion material is not good, and transfusion device in use breakage, the phenomenon of leakage can occur.
(4) non-PVC transfusion device raw material and manufacturing cost are unfavorable for promoting the use of far above the polrvinyl chloride transfusion device.
Summary of the invention
Safety problem at the polrvinyl chloride transfusion device exists the invention provides a kind of safe infusion apparatus and preparation method.
A kind of safe infusion apparatus provided by the invention comprises dropping funnel and tube for transfusion; Described dropping funnel and tube for transfusion are the manufacturing of urethane/polyvinyl chloride double-layer composite material;
Described urethane/polyvinyl chloride double-layer composite material dropping funnel interior surface layers is a layer of polyurethane, and outer surface layer is a polyvinyl chloride layer, and layer of polyurethane is 1 with the thickness ratio of polyvinyl chloride layer: 2-5; The optimization polyurethane layer thickness is 0.1-0.4mm, and the polrvinyl chloride layer thickness is 0.4-0.8mm;
Described urethane/polyvinyl chloride double-layer composite material dropping funnel profile as shown in Figure 1.Among Fig. 1,1. polyurethane internal layer; 2. polrvinyl chloride skin
The interior surface layers of described urethane/polyvinyl chloride two-layer compound tube for transfusion is a layer of polyurethane, and outer surface layer is a polyvinyl chloride layer, and layer of polyurethane is 1 with the thickness ratio of polyvinyl chloride layer: 2-8; The optimization polyurethane layer thickness is 0.05-0.35mm, and the polrvinyl chloride layer thickness is 0.35-0.80mm;
Described urethane/polyvinyl chloride double-layer composite material tube for transfusion profile as shown in Figure 2.Among Fig. 2,3. layer of polyurethane; 4. polyvinyl chloride layer
Described polyurethane is Polyurethane Thermoplastic Elastomer, its melt flow rate (MFR) 1-10, shore hardness≤80, hot strength 〉=13MPa, elongation at break 〉=250%;
Described polrvinyl chloride is plastifying flexible PVC, its shore hardness≤80, hot strength 〉=13MPa, elongation at break 〉=250%.
Below introduce a kind of preparation method of safe infusion apparatus, comprise the preparation method of urethane/polyvinyl chloride double-layer composite material dropping funnel and urethane/polyvinyl chloride double-layer composite material tube for transfusion.
(1) urethane/polyvinyl chloride double-layer composite material dropping funnel adopts the coextrusion blow moulding, its step and condition are as follows: adopt double-layer coextrusion blowing unit, this unit is made up of two extruders and a co-extruding blow moulding machine head, and described co-extruding blow moulding machine head adopts the outer side-fed co-extruding blow moulding machine of internal layer central feeding head, ectonexine all the core rod type co-extruding blow moulding machine head or the outer all central feeding co-extruding blow moulding machine heads of internal layer of charging from the side;
The polyurethane extruder temperature is: feed zone 140-160 ℃, and compression section 150-180 ℃, metering section 160-190 ℃; The polyvinyl-chloride use extruder temperature is: feed zone 130-150 ℃, and compression section 150-170 ℃, metering section 160-180 ℃; Co-extruding blow moulding machine head temperature is 160-180 ℃;
After polyurethane and polrvinyl chloride oven dry, by weight adding in the polyurethane extruder hopper and polrvinyl chloride extruder hopper of double-layer coextrusion blowing unit respectively, regulate the die orifice of co-extruding blow moulding machine head and the thickness of air blowing parameter change urethane/polyvinyl chloride double-layer composite material, change polyurethane extruder and polrvinyl chloride extruder feed rate than layer of polyurethane and the polrvinyl chloride layer thickness ratio of regulating double-layer composite material, urethane/polyvinyl chloride double-layer composite material vane cooling with blowing, draw by carry-over pinch rolls, collect with the rustless steel pallet;
(2) urethane/polyvinyl chloride double-layer composite material tube for transfusion adopts coetrusion, and its step and condition are as follows: adopt the bimetallic tube unit; This unit is made up of two extruders and a coextrusion bimetallic tube head, and coextrusion bimetallic tube head adopts all outer all central feeding coextrusion bimetallic tube heads of charging core rod type coextrusion bimetallic tube head or internal layer from the side of the outer side-fed coextrusion of internal layer central feeding bimetallic tube head, ectonexine;
The polyurethane extruder temperature is: feed zone 140-170 ℃, and compression section 160-190 ℃, metering section 170-200 ℃; The polyvinyl-chloride use extruder temperature is: feed zone 140-160 ℃, and compression section 160-180 ℃, metering section 170-190 ℃; Coextrusion bimetallic tube head temperature is 170-190 ℃;
After polyurethane and polrvinyl chloride oven dry, by weight adding in the polyurethane extruder hopper and polrvinyl chloride extruder hopper of coextrusion bimetallic tube unit respectively, the die orifice change of adjusting coextrusion bimetallic tube head) thickness of urethane/polyvinyl chloride double-layer composite material tube for transfusion, change polyurethane extruder and polrvinyl chloride extruder feed rate than the thickness ratio of regulating layer of polyurethane and polyvinyl chloride layer, with what extrude) urethane/polyvinyl chloride double-layer composite material tube for transfusion cools off by bosh, draw by carry-over pinch rolls, collect with the rustless steel pallet;
With solvent adhesive with urethane/polyvinyl chloride double-layer composite material dropping funnel, urethane/polyvinyl chloride double-layer composite material tube for transfusion, wear a bottle pin and link together, accessories such as assembling fluid flow regulator and intravenous needle make safe infusion apparatus.
Beneficial effect: safe infusion apparatus provided by the invention, comprise urethane/polyvinyl chloride double-layer composite material dropping funnel and urethane/polyvinyl chloride double-layer composite material tube for transfusion, the inner surface of two-layer composite dropping funnel and double-layer composite material tube for transfusion is layer of polyurethane.The surface that this safe transfusion system contacts with medicinal liquid all is non-PVC materials, and the plasticizer, heat stabilizer and the Vinyl Chloride Monomer that have solved in the polrvinyl chloride transfusion device enter medicinal liquid, the problem that is detrimental to health.Overcome polrvinyl chloride transfusion device and drug reaction or absorption medicine simultaneously, made the prescription medication inaccurate, incured loss through delay the defective of rehabilitation duration.Polyurethane and pvc material that this safe transfusion system adopts have the compatibility preferably, preparation double-layer composite material dropping funnel and tube for transfusion interlaminar bonding performance are better, and good mechanical performance is fit to high-frequency welding, cost is far below non-PVC material, and large-scale promotion application suits.
Description of drawings
Fig. 1 is the profile of urethane/polyvinyl chloride double-layer composite material dropping funnel dropping funnel wall.
Fig. 2 is a urethane/polyvinyl chloride double-layer composite material tube for transfusion profile.
The specific embodiment
The numbering and the physical index of embodiment material therefor see table 1 for details.
Table 1
| The component code name | Trade name | Model | Manufacturer | Hardness (Shao Shi A) |
| A1 | Polyurethane | S-6558 | Hensel steps (China) company limited | ?77 |
| A2 | Polyurethane | E-4675 | Hensel steps (China) company limited | ?70 |
| B1 | Polrvinyl chloride | S-1000 | Qilu Petrochemical limited company | ?78 |
| B2 | Polrvinyl chloride | DS01 | Big electric plastics (Shanghai) Co., Ltd. | ?77 |
Embodiment 1
Take by weighing A1, B1 material, add respectively in the double-layer coextrusion blowing unit, the screw diameter of extruding unit is 40mm, and draw ratio is 36, and head is the outer side-fed coextrusion of an internal layer central feeding blow-molded plastic.Set 150-160 ℃ of extruder feed zone temperature of A1 material, compression section temperature 160-170 ℃, 170-180 ℃ of metering section temperature; Set 140-155 ℃ of extruder feed zone temperature of B1 material, compression section temperature 150-165 ℃, 160-175 ℃ of metering section temperature; Set 170-180 ℃ of co-extruding blow moulding machine head temperature.
After polyurethane and polrvinyl chloride oven dry, weight ratio is respectively to add at 1: 4 in the polyurethane extruder hopper and polrvinyl chloride extruder hopper of double-layer coextrusion blowing unit, setting polyurethane extruder, vinyl chloride extruder feed rate ratio are 1: 3.5, urethane/polyvinyl chloride double-layer composite material vane cooling with blowing, draw by carry-over pinch rolls, collect with the rustless steel pallet;
Take by weighing A2, B1 material respectively, add in the coextrusion bimetallic tube unit, the screw diameter of extruding unit is 40mm, and draw ratio is 36, and head is all charging core rod type coextrusion two-layer pipes from the side of ectonexine.Set 150-165 ℃ of extruder feed zone temperature of A2 material, compression section temperature 160-175 ℃, 170-185 ℃ of metering section temperature; Set 140-160 ℃ of extruder feed zone temperature of B1 material, compression section temperature 150-170 ℃, 165-175 ℃ of metering section temperature; Set 170-185 ℃ of coextrusion bimetallic tube head temperature.After polyurethane and polrvinyl chloride oven dry, weight ratio be set the polyurethane extruder in 1: 5 polyurethane and the polrvinyl chloride polyurethane extruder hopper that adds coextrusion bimetallic tube unit respectively and the polrvinyl chloride extruder hopper, vinyl chloride extruder feed rate ratio is 1: 4, the urethane/polyvinyl chloride double-layer composite material tube for transfusion of extruding is cooled off by bosh, draw by carry-over pinch rolls, collect with the rustless steel pallet;
With solvent adhesive with urethane/polyvinyl chloride double-layer composite material, the urethane/polyvinyl chloride double-layer composite material tube for transfusion of cutting, wear a bottle pin and link together, accessories such as assembling fluid flow regulator and intravenous needle make safe infusion apparatus.
Embodiment 2
Take by weighing A1, B2 material, add respectively in the double-layer coextrusion blowing unit, the screw diameter of extruding unit is 40mm, and draw ratio is 36.Set 150-160 ℃ of extruder feed zone temperature of A1 material, compression section temperature 160-170 ℃, 170-180 ℃ of metering section temperature; Set 140-155 ℃ of extruder feed zone temperature of B2 material, compression section temperature 150-165 ℃, 160-175 ℃ of metering section temperature; Set 170-180 ℃ of co-extruding blow moulding machine head temperature.After polyurethane and polrvinyl chloride oven dry, weight ratio is respectively to add at 1: 3 in the polyurethane extruder hopper and polrvinyl chloride extruder hopper of double-layer coextrusion blowing unit, setting polyurethane extruder, vinyl chloride extruder feed rate ratio are 1: 2.4, urethane/polyvinyl chloride double-layer composite material vane cooling with blowing, draw by carry-over pinch rolls, collect with the rustless steel pallet.
Take by weighing A2, B2 material, add respectively in the coextrusion bimetallic tube unit, the screw diameter of extruder is 40mm, and draw ratio is 36.Set 155-170 ℃ of extruder feed zone temperature of A2 material, compression section temperature 165-180 ℃, 175-190 ℃ of metering section temperature; Set 150-165 ℃ of extruder feed zone temperature of B2 material, compression section temperature 155-175 ℃, 165-185 ℃ of metering section temperature; Set 170-185 ℃ of coextrusion bimetallic tube head temperature.After polyurethane and polrvinyl chloride oven dry, weight ratio be set the polyurethane extruder in 1: 3 polyurethane and the polrvinyl chloride polyurethane extruder hopper that adds coextrusion bimetallic tube unit respectively and the polrvinyl chloride extruder hopper, vinyl chloride extruder feed rate ratio is 1: 2.4, with cooling off by bosh of extruding to urethane/polyvinyl chloride double-layer composite material tube for transfusion, draw by carry-over pinch rolls, collect with the rustless steel pallet.
With solvent adhesive with urethane/polyvinyl chloride double-layer composite material dropping funnel, urethane/polyvinyl chloride double-layer composite material tube for transfusion, wear a bottle pin and link together, accessories such as assembling fluid flow regulator and intravenous needle make safe infusion apparatus.
Claims (3)
1. a safe infusion apparatus comprises dropping funnel and tube for transfusion, it is characterized in that, described dropping funnel and tube for transfusion are the manufacturing of urethane/polyvinyl chloride double-layer composite material;
Described urethane/polyvinyl chloride double-layer composite material dropping funnel interior surface layers is a layer of polyurethane, and outer surface layer is a polyvinyl chloride layer, and layer of polyurethane is 1 with the thickness ratio of polyvinyl chloride layer: 2-5;
The interior surface layers of described urethane/polyvinyl chloride two-layer compound tube for transfusion is a layer of polyurethane, and outer surface layer is a polyvinyl chloride layer, and layer of polyurethane is 1 with the thickness ratio of polyvinyl chloride layer: 2-8;
Described polyurethane is Polyurethane Thermoplastic Elastomer, its melt flow rate (MFR) 1-10, shore hardness≤80, hot strength 〉=13MPa, elongation at break 〉=250%;
Described polrvinyl chloride is plastifying flexible PVC, its shore hardness≤80, hot strength 〉=13MPa, elongation at break 〉=250%;
The preparation method of described a kind of safe infusion apparatus comprises the preparation method of urethane/polyvinyl chloride double-layer composite material dropping funnel and urethane/polyvinyl chloride double-layer composite material tube for transfusion:
(1) urethane/polyvinyl chloride double-layer composite material dropping funnel adopts the coextrusion blow moulding, its step and condition are as follows: adopt double-layer coextrusion blowing unit, this unit is made up of two extruders and a co-extruding blow moulding machine head, and described co-extruding blow moulding machine head adopts the outer side-fed co-extruding blow moulding machine of internal layer central feeding head, ectonexine all the core rod type co-extruding blow moulding machine head or the outer all central feeding co-extruding blow moulding machine heads of internal layer of charging from the side;
The polyurethane extruder temperature is: feed zone 140-160 ℃, and compression section 150-180 ℃, metering section 160-190 ℃; The polyvinyl-chloride use extruder temperature is: feed zone 130-150 ℃, and compression section 150-170 ℃, metering section 160-180 ℃; Co-extruding blow moulding machine head temperature is 160-180 ℃;
After polyurethane and polrvinyl chloride oven dry, by weight adding in the polyurethane extruder hopper and polrvinyl chloride extruder hopper of double-layer coextrusion blowing unit respectively, regulate the die orifice of co-extruding blow moulding machine head and the thickness of air blowing parameter change urethane/polyvinyl chloride double-layer composite material, change polyurethane extruder and polrvinyl chloride extruder feed rate than layer of polyurethane and the polrvinyl chloride layer thickness ratio of regulating double-layer composite material, urethane/polyvinyl chloride double-layer composite material vane cooling with blowing, draw by carry-over pinch rolls, collect with the rustless steel pallet;
(2) urethane/polyvinyl chloride double-layer composite material tube for transfusion adopts coetrusion, and its step and condition are as follows: adopt the bimetallic tube unit; This unit is made up of two extruders and a coextrusion bimetallic tube head, and coextrusion bimetallic tube head adopts all outer all central feeding coextrusion bimetallic tube heads of charging core rod type coextrusion bimetallic tube head or internal layer from the side of the outer side-fed coextrusion of internal layer central feeding bimetallic tube head, ectonexine;
The polyurethane extruder temperature is: feed zone 140-170 ℃, and compression section 160-190 ℃, metering section 170-200 ℃; The polyvinyl-chloride use extruder temperature is: feed zone 140-160 ℃, and compression section 160-180 ℃, metering section 170-190 ℃; Coextrusion bimetallic tube head temperature is 170-190 ℃;
After polyurethane and polrvinyl chloride oven dry, by weight adding in the polyurethane extruder hopper and polrvinyl chloride extruder hopper of coextrusion bimetallic tube unit respectively, the die orifice change of adjusting coextrusion bimetallic tube head) thickness of urethane/polyvinyl chloride double-layer composite material tube for transfusion, change polyurethane extruder and polrvinyl chloride extruder feed rate than the thickness ratio of regulating layer of polyurethane and polyvinyl chloride layer, with what extrude) urethane/polyvinyl chloride double-layer composite material tube for transfusion cools off by bosh, draw by carry-over pinch rolls, collect with the rustless steel pallet;
With solvent adhesive with urethane/polyvinyl chloride double-layer composite material dropping funnel, urethane/polyvinyl chloride double-layer composite material tube for transfusion, wear a bottle pin and link together, accessories such as assembling fluid flow regulator and intravenous needle make safe infusion apparatus.
2. a kind of safe infusion apparatus as claimed in claim 1 is characterized in that, described urethane/polyvinyl chloride double-layer composite material dropping funnel, and layer of polyurethane thickness is 0.1-0.4mm, the polrvinyl chloride layer thickness is 0.4-0.8mm.
3. a kind of safe infusion apparatus as claimed in claim 1 is characterized in that, described urethane/polyvinyl chloride two-layer compound tube for transfusion, and layer of polyurethane thickness is 0.05-0.35mm, the polrvinyl chloride layer thickness is 0.35-0.80mm.
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| CN2009100668534A CN101537216B (en) | 2009-04-21 | 2009-04-21 | Safe infusion apparatus and preparation method thereof |
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| CN2009100668534A CN101537216B (en) | 2009-04-21 | 2009-04-21 | Safe infusion apparatus and preparation method thereof |
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| CN101537216B true CN101537216B (en) | 2011-08-10 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101804226A (en) * | 2010-04-02 | 2010-08-18 | 江西三鑫医疗器械集团有限公司 | Low adsorption multi-layer co-extrusion light proofing infusion apparatus |
| CN101797407A (en) * | 2010-04-02 | 2010-08-11 | 山东威高集团医用高分子制品股份有限公司 | Infusion apparatus assembly process |
| CN102152105B (en) * | 2011-05-12 | 2012-04-18 | 合肥工业大学 | Automatic bottle-inserting needle and catheter assembling device for disposable transfusion apparatuses |
| CN102501503A (en) * | 2011-10-19 | 2012-06-20 | 山东威高集团医用高分子制品股份有限公司 | Dropping funnel bottle of blood transfusion apparatus and preparation method thereof |
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| CN101537216A (en) | 2009-09-23 |
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