Background technology
Diabetes are a kind of common incretion metabolism diseases, are engulfing our healthy life day by day, and the morbidity of diabetes increases rapidly.Become the third-largest healthy killer who is only second to tumor, cardiovascular and cerebrovascular disease, brought significant damage and financial burden for patient family.
Diabetes are a kind of lifelong participation diseases.The sugared concentration that shows as in the blood raises and glycosuria.Contain certain density glucose in normal person's the blood, be called for short blood glucose, provide the active main energy source of people.After feed, the concentration of glucose in the blood raises, and under the effect of insulin, the glucose in the blood enters in the cell, and the concentration of glucose in the blood is reduced, and makes it to maintain in the normal range.The glucose that enters cell simultaneously is through series of biochemical reactions, for people's activity provides energy.When shortage insulin or insulin can not effectively play a role in the human body, the glucose in the blood can not enter by normal mode and carry out metabolism in the cell, and the glucose level in the blood increases unusually, and diabetes take place.So-called diabetic complication, be such definition in the WHO diabetes statement: diabetic complication is because diabetes and diabetes spp blood sugar condition and the acute or chronic disease and the clinical symptoms of secondary, and to spell out diabetic complication be the principal element of left and right sides patient after more.Brainstrust is found in the clinical position, and the diabetic complication that influences diabetics health, work, life and life-span mainly contains: infection, ketoacidosis, diabetic nephropathy, heart change, neuropathy, eye pathological changes, diabetic foot.
Diabetes are divided into two kinds, and type 1 diabetes occurs between child and the teenager, account for whole patients' 5-10%, and it mainly shows is that human body can not be secreted enough insulins.The morbidity of type ii diabetes thinks it mainly is that the physiological process of β cell-specific receptors bind of insulin and histoorgan morphs at present, thereby make insulin can not bring into normal play physiological action and the disease that forms, inherited genetic factors and environmental factors (comprise age, obesity and overweight, physical exertion minimizing, psychentonia, nutrition cross and contain and bad and infection and medicine etc.) its pathogenic process of fellowship based on carbohydrate metabolism disturbance at the β cell.Primary disease promptly is " quenching one's thirst " disease in the Chinese medicine.The traditional Chinese medical science is to the understanding of diabetes, and is with a long history, of long standing and well established.Promptly think the substantial connection that has of factors such as surfeit delicious food, disorder of emotion, the five internal organs weakness and primary disease in the Huangdi's Internal Classics, call as " element is asked strange sick opinion ": " this person must count the sweet and refreshing and many fertilizer of food also, overeating greasy food bringing about internal heat, over-eating the food with sweet flavor bringing about abdominal distension; so its gas overflow transfers to and quenching one's thirst." " Ling Shu Miraculous Pivot or Divine Axis five become a piece of writing " says: " and rage causing upward adverse flow of liver-QI is contrary, accumulates in the heart, and the vim and vigour adverse current, the hip skin fills flesh, and blood vessels are not all right, then for hot, and the heat skin that then disappears is so be diseases due to endogenous heat of ZANG FU organs." add: " all gentle weak person of the five internal organs, kind disease disappears overworked." understanding of the primary disease cause of disease has been consisted essentially of existing type ii diabetes is the adult to visible ancients basically, though in these patient's bodies enough insulins are arranged, all can not effectively allow it play a role.
At present, the patient of most diabetes relies on certain drug to come mitigate the disease, the infringement patient's that the complication of diabetes is serious human body causes cardio cerebrovascular affection, eye pathological changes, nephropathy, neuropathy, take the metformin antidiabetic drug throughout the year, cause many complication such as ketoacidosis.
The most of usefulness of medicine of treatment diabetes is diabetes pill, glyburide, metformin class Chinese patent medicine and certain import medicine at present, though it is effective in cure, but all drink poison to quench thirst, with the injury Liver and kidney is cost, the original Liver and kidney of diabetes patient seriously comes to harm, these medicines make the matter worse especially, have played to allow patient's the more serious phenomenon of complication, allow patient's the state of an illness further worsen.
Summary of the invention
Chinese medicine preparation of the treatment diabetes that the technical problem to be solved in the present invention provides a kind of curative effect height, have no side effect and preparation method thereof.
The technical scheme that the present invention solves the problems of the technologies described above employing is:
The Chinese medicine preparation of treatment diabetes, each component is by weight: Herba cassiae occidentalis 40-90 part, Radix Rehmanniae 30-90 part, Radix Astragali 60-70 part, Rhizoma Dioscoreae 60-80 part, Radix Scrophulariae 30-70 part, Rhizoma Atractylodis 40-80 part, Rhizoma Anemarrhenae 30-80 part, Herba Dendrobii 30-80 part, Rhizoma Polygonati Odorati 30-70 part and Radix Panacis Quinquefolii 20-70 part.
The Chinese medicine preparation of treatment diabetes, the dosage form of this Chinese medicine preparation is: oral Chinese medicine liquid, concentrated granular electuary, tablet and capsular wherein a kind of.
The method for preparing the Chinese medicine preparation of treatment diabetes according to claim 1, this method is as follows: each raw material is carried out the strictness screening, purify, oven dry takes by weighing, and makes various types of pharmaceutical preparatioies then.
The technological progress that the present invention obtains is:
The present invention adopts above technical scheme, is used for the treatment of diabetes and complication, has the kidney invigorating, spleen invigorating, QI invigorating, bactericidal antiphlogistic, the blood pressure lowering of invigorating blood circulation, and blood viscosity lowering and blood glucose do not have side effects, and reach treating both the principal and secondary aspects of a disease, and therapeutic effect is very desirable.
The effect that the present invention treats the Chinese medicine preparation of diabetes is, the equilibrium between yin and yang of tracking human body is removed rubbish in the blood vessel, dredge the meridian passage, blood circulation promoting and blood stasis dispelling, vessel softening, blood fat reducing, blood sugar lowering, cholesterol reducing activate patient self insulin function, himself insulin is played a role, improve high density lipoprotein, reduce low density lipoprotein, LDL, eliminate GAS.
Take that effective percentage is 100% in the medicine of the present invention 60 days the general diabetes initial stage, effective percentage is 100% in the cure rate 92%, type ii diabetes 90 days, and cure rate is 93%.
The Chinese medicine preparation side that the present invention treats diabetes separates as follows:
Herba cassiae occidentalis: nature and flavor are sweet flat, and function cures mainly, the liver heat removing dampness removing, and relieving stranguria by diuresis, the dissipating blood stasis removing food stagnancy is controlled five types of stranguria, edema, and the transconversion into heat that disappears is eaten, is promoted the production of body fluid, and controls infantile malnutrition, ends excessive thirst.
The Radix Rehmanniae: nature and flavor, sweetness and bitterness is cold.Function cures mainly, clearing away heat and cooling blood, hemostasis, and YIN nourishing is flat to nourish blood, bleeding due to blood-heat, hematemesis and epistaxis is had blood in stool, woman uterine bleeding, heat is gone into blood part, sends out the speckle dermexanthesis, upset and mania, heat is bright cloudy withered, and low grade fever does not move back, dysphoria with feverish sensation in the chest palms and soles.
The Radix Astragali: nature and flavor, Gan Wen, function cures mainly, tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the holder skin ulcer rises flesh, deficiency of both the splenic and pulmonary QI stasis, arthralgia, numbness.
Rhizoma Dioscoreae: nature and flavor, sweet flat, function cures mainly, instability of kidney QI, seminal emission leukorrhagia, frequent micturition, deficiency of both the splenic and pulmonary QI, diarrhea abdominal distention, lack of appetite asthenia, thin and weak cough, is quenched one's thirst flat nourishing YIN sun at asthma, dysphoria with smothery sensation, especially be outstanding to nourish spleen the moon, the property of medicine is flat not dry, specially useful in spleen the moon; " be one of choice drug of treatment diabetes, normal and Radix Astragali compatibility uses.
Radix Scrophulariae: nature and flavor, sweetness and bitterness is salty to be slightly cold, and function cures mainly, nourishing YIN to lower pathogenic fire, heat-clearing and toxic substances removing, disease is controlled, thermal burn nutrient blood, send out the speckle dermexanthesis, vexed coma, hyperactivity of deficient fire, pharyngalgia, diphtheria, conjunctival congestion, aphtha, the vehement impairment of body fluid of heat, dry mouth and tougue, constipation, scorchingly hot pent-up, scrofula are not moved back in heating.
Rhizoma Atractylodis: nature and flavor, arduous temperature, function cures mainly, and is drying damp and strengthening spleen, the diaphoresis of dispeling the wind, damp pathogen obstructing the spleen, distension and fullness in the abdomen, inappetence, the heavy sensation of the body limb is tired, the dairrhea caused by pathogenic damp edema, rheumatic Bi syndrome, jointed appendage bodily pain or swollen, damp invasion of lower energizer, sufficient knee joint is weak or swollen.
The Rhizoma Anemarrhenae: nature and flavor, bitter sweet cold, function cures mainly, the YIN nourishing lung heat clearing, analgesic relieving restlessness, the deficiency of YIN, hyperactivity of fire, the consumptive fever hectic fever due to YIN-deficiency, vexed cough, spitting of blood, lung intimately burns.
Herba Dendrobii: nature and flavor, sweet light little salty, be slightly cold, function cures mainly, reinforcing stomach reg fluid, the YIN nourishing heat extraction, deficiency of stomach-Yin, the xerostomia excessive thirst, the withered deficiency-heat in Tianjin is retched after being ill, and diet is not fragrant, and few Tianjin falls in tongue, rheumatism pyretic arthralgia, foot weakness.
Rhizoma Polygonati Odorati: nature and flavor, sweet being slightly cold, function cures mainly, nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst, YIN-fluid being insufficient, the cough due to deficiency of the lung, expectorant is told unfavorable, pharyngalgia, dry cough is lost blood, the hectic fever due to YIN-deficiency consumptive fever, xerostomia is quenched one's thirst, the easy flesh of polyphagia, vexed, constipation.
Radix Panacis Quinquefolii: nature and flavor, it is cool to work hard, and function cures mainly, deficiency of both QI and YIN, the chronic cough consumptive lung disease, the asthma hemoptysis, aphonia, the deficiency of YIN has fire, the asthenic fire toothache, tired tired Tianjin is few thirsty, consumption of YIN caused by febrile disease, with the passing of time interior-heat caused by deficiency of YIN does not move back after being ill.
Make a general survey of full side, all medicine compatibilities bring out the best in each other, and play benefiting QI and nourishing blood altogether, qi and blood tonifying, and blood circulation promoting and blood stasis dispelling, the merit of heat-clearing and toxic substances removing, effective, instant effect has determined curative effect, the characteristics of quick result.
The present invention treats the Chinese medicine preparation of diabetes; broken through the treatment means of traditional single blood sugar lowering; balance human body negative and positive; blood sugar lowering; trace element supplement; start with in aspects such as blood pressure regulation blood fat; make drug molecule enter blood fast, can increase serum insulin content fast, improve the permeability and the function of motion of cells in vivo film; increase the physiological reaction of cell and glucose; and effectively stoped the hepatic glycogen decomposition, and patient's blood glucose is descended fast, quicken to activate β cell regeneration; reduce the opposing of α cell; promote insulin secretion, suppressed the heteroplasia of sugar, regulated sugar; fat; proteinic metabolic imbalance; thereby maintenance blood glucose; glucose in urine is stable; improve immunity, absorbed certain remarkable blood fat reducing simultaneously; the antithrombotic effect has been protected the heart; brain; liver; important organ pipe such as kidney; effectively eliminated complication, the final diabetes of thoroughly curing.
We respectively get its long, complementary its short principle prescription according to Chinese medicine and western medicine, give full play to the blood sugar lowering effect of Western medicine, the advantage of Chinese herb prevention chronic complicating diseases, take into account the gastrointestinal reaction that alleviates Western medicine with Chinese medicine, stop the glibenclamide secondary failure, adopt traditional method to make quick-acting, efficient, permanent Jiangtang capsule of imitating.
Compound Chinese medicinal preparation of the present invention is compared with existing medicine, has following feature: 1. pure Chinese medicinal preparation; 2. the method for effecting a permanent cure of supplementing QI and nourishing YIN and the method for taking stopgap measures of blood circulation promoting and blood stasis dispelling are combined, thereby reach treating both the principal and secondary aspects of a disease.The special purpose of taking a tonic or nourishing food to build up one's health spleen the moon that embodies.3. prescription is rigorous, and the function of monarch is clearly demarcated.4. the clinical application several years, curative effect is sure, except that the effect that blood sugar lowering is arranged, can also regulate the blood lipid level of body.5. cheap.
The inventor is to 200 routine case clinical observations, male 150 people wherein, women 50 people, 30 years old-75 years old age, course of disease 2-15, by taking medicine of the present invention, general medication 2-3 course of treatment, 185 people healing, it is effective that cure rate reaches 92%, 200 people, and effective percentage is 100%.
The specific embodiment
Embodiment 1: the Chinese medicine preparation of this treatment diabetes adopts the preparation of following weight component: Herba cassiae occidentalis 35g, Radix Rehmanniae 30g, Radix Astragali 30g, Rhizoma Dioscoreae 25g, Radix Scrophulariae 20g, Rhizoma Atractylodis 25g, Rhizoma Anemarrhenae 25g, Herba Dendrobii 20g, Rhizoma Polygonati Odorati 20g and Radix Panacis Quinquefolii 15g.
Preparation method: each raw material is carried out the strictness screening, purify, oven dry takes by weighing, and then, pharmaceutical technology, flow process produce various types of pharmaceutical preparatioies routinely, as make oral Chinese medicine liquid, concentrated granular electuary, tablet and capsule.Instructions of taking: after the raw material of above-mentioned weight was made the Chinese medicine preparation of this treatment diabetes, at twice or take for three times, 30 days was a course of treatment in one day.
Embodiment 2-5 adopts the feedstock production of following weight, preparation method and taking with embodiment 1.
? |
2? |
3? |
4? |
5? |
Herba cassiae occidentalis (g) |
40? |
80? |
50? |
90? |
The Radix Rehmanniae (g) |
90? |
30? |
80? |
70? |
The Radix Astragali (g) |
60? |
70? |
60? |
55? |
Rhizoma Dioscoreae (g) |
80? |
40? |
50? |
60? |
Radix Scrophulariae (g) |
30? |
70? |
55? |
60? |
Rhizoma Atractylodis (g) |
80? |
40? |
60? |
75? |
The Rhizoma Anemarrhenae (g) |
30? |
80? |
55? |
70? |
Herba Dendrobii (g) |
80? |
30? |
35? |
50? |
Rhizoma Polygonati Odorati (g) |
30? |
70? |
55? |
60? |
Radix Panacis Quinquefolii (g) |
70? |
20? |
45? |
55? |
Model case:
Case history 1, Liu, woman 62 years old, Han nationality, the workman suffered from diabetes before 21 years, through tentatively treatment, blood glucose is steady substantially, the egg hematuria ++ ++ remove, think that just glycosuria heals, just do not take medicine, for 1 year, follow-up diabetes are shown effect again, adhere to exactly not taking medicine that the people is by more than the 150 jin of jin surplus 70 that fall sharply, and is worn to a shadow, its mother has advised and has been its preparation funeral affairs, after patient persuasion its promise to take medicine that through obeying 15 days our Chinese medicine, blood glucose is by 1.08mmol/L before the meal, reduce to 7.1mmol/L, 18.5mmol/L reduces to 12.3mmol/L after the meal, after again Ben Biming Chinese medicine is made capsule, early, noon, respectively obey 4 evening, take its 110 jin of weight recovery three courses of treatment (three months), blood glucose has been reduced to 6.0mmol/L before the meal, and post-prandial glycemia is reduced to 11.0mmol/L, its people got well in the past in 21 years.Following up a case by regular visits to does not have recurrence, thoroughly cures.
Case history 2, Lin, 41 years old, the man suffered from diabetes 3 years, and edema pruritus is from head to foot arranged, and took glyburide, diformin tablet all the year round, caused the Liver and kidney major injury, and taste digestion is also influenced, blood glucose 9.7mmol/L before the meal, post-prandial glycemia 17.5mmol/L.Through taking three courses of treatment of Chinese medicine preparation capsule of the present invention, the anasarca pruritus heals, and blood glucose is reduced to 6.1mmol/L before the meal, and post-prandial glycemia is reduced to 8.2mmol/L.
Case history 3, Wang 55 years old, suffered from diabetes 5 years, obey blood sugar lowering class, diformin tablet, disappear and drank ball 5 years, cause four liver numbness, prurituss from head to foot, trick is ice-cold, blood glucose 8.5mmol/L before the meal, post-prandial glycemia 16.8mmol/L, through taking three and half courses of treatment of Chinese medicine preparation of the present invention, numb limbs and tense tendons, pruritus is removed from head to foot, and trick is warm, blood glucose has been reduced to 5.9mmol/L before the meal, and post-prandial glycemia is reduced to 8.8mmol/L.
Case history 4, Deng, 47 years old, the man, the cadre suffered from diabetes 6 years, and the normal phase is taken glyburide, diformin tablet, causes ketoacidosis, medicinal too much kind in using instead, but blood glucose rises and falls always, and the blurring of vision symptom has appearred.Through taking four courses of treatment of capsule of the present invention, all diseases are healed, and it is clear to look thing.Following up a case by regular visits to does not have recurrence, thoroughly cures.
Case history 5, Lee, 61 years old, man, retired worker, suffered from diabetes 8 years, concurrent cardiovascular symptom, medicines such as orally-taken blood sugar reducing spirit, metformin are treated, and the back blood glucose of at every turn taking medicine descends, but drug withdrawal just has a rebound, vexed insomnia, and the vexed pain in ambition is the cardiovascular complication that diabetes cause through looking into.Through taking capsule of the present invention after three courses of treatment, complication disappears, and through observing 2 years, patient's blood glucose is steady.
Case history 6, Lee, 48 years old, the woman suffered from diabetes 7 years, took insoral, diformin tablet all the year round, caused numb limbs and tense tendons, and pain sees that thing is fuzzy, fasting glucose 9.9mmol/L, post-prandial glycemia 17.3mmol/L.
Through taking four courses of treatment of Chinese medicine preparation capsule of the present invention, the not numb pain of extremity sees that thing is fuzzy, and the anasarca pruritus heals, and fasting glucose is reduced to 6.0mmol/L, and post-prandial glycemia is reduced to 8.9mmol/L.Through tracing observation 6 years, the patient no longer take other medicines blood glucose before the meal, all normal, healthy after the meal.Following up a case by regular visits to does not have recurrence, thoroughly cures.