CN101507822B - 皮肤瘢痕形成的减少 - Google Patents

皮肤瘢痕形成的减少 Download PDF

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Publication number
CN101507822B
CN101507822B CN2009101287188A CN200910128718A CN101507822B CN 101507822 B CN101507822 B CN 101507822B CN 2009101287188 A CN2009101287188 A CN 2009101287188A CN 200910128718 A CN200910128718 A CN 200910128718A CN 101507822 B CN101507822 B CN 101507822B
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China
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rad
waf1
cip1
cell
wound
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Expired - Fee Related
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CN2009101287188A
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English (en)
Chinese (zh)
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CN101507822A (zh
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D·古
M·泽佩达
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Canji Inc
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Canji Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN2009101287188A 2003-11-24 2004-11-23 皮肤瘢痕形成的减少 Expired - Fee Related CN101507822B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52499303P 2003-11-24 2003-11-24
US60/524993 2003-11-24

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNB2004800406132A Division CN100482674C (zh) 2003-11-24 2004-11-23 皮肤瘢痕形成的减少

Publications (2)

Publication Number Publication Date
CN101507822A CN101507822A (zh) 2009-08-19
CN101507822B true CN101507822B (zh) 2012-06-06

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ID=34632948

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CN2009101287188A Expired - Fee Related CN101507822B (zh) 2003-11-24 2004-11-23 皮肤瘢痕形成的减少
CNB2004800406132A Expired - Fee Related CN100482674C (zh) 2003-11-24 2004-11-23 皮肤瘢痕形成的减少

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CNB2004800406132A Expired - Fee Related CN100482674C (zh) 2003-11-24 2004-11-23 皮肤瘢痕形成的减少

Country Status (13)

Country Link
US (3) US7465442B2 (https=)
EP (1) EP1692154A4 (https=)
JP (2) JP4842139B2 (https=)
KR (1) KR101167330B1 (https=)
CN (2) CN101507822B (https=)
AU (1) AU2004293474B2 (https=)
BR (1) BRPI0416920A (https=)
CA (1) CA2546287C (https=)
IL (1) IL175603A (https=)
NO (1) NO20062978L (https=)
NZ (1) NZ546983A (https=)
WO (1) WO2005051971A1 (https=)
ZA (1) ZA200604147B (https=)

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CN101507822B (zh) * 2003-11-24 2012-06-06 坎吉有限公司 皮肤瘢痕形成的减少
US8287538B2 (en) 2008-01-14 2012-10-16 Conventus Orthopaedics, Inc. Apparatus and methods for fracture repair
EP2342340A1 (en) 2008-09-22 2011-07-13 Rxi Pharmaceuticals Corporation Rna interference in skin indications
WO2011088172A1 (en) 2010-01-15 2011-07-21 Brenzel Michael P Rotary-rigid orthopaedic rod
CA2823873A1 (en) 2010-01-20 2011-07-28 Conventus Orthopaedics, Inc. Apparatus and methods for bone access and cavity preparation
CA2829193A1 (en) 2010-03-08 2011-09-15 Conventus Orthopaedics, Inc. Apparatus and methods for securing a bone implant
EP3560503B1 (en) 2010-03-24 2021-11-17 Phio Pharmaceuticals Corp. Rna interference in dermal and fibrotic indications
CN105960265A (zh) * 2013-12-04 2016-09-21 阿克赛医药公司 利用经化学修饰的寡核苷酸处理伤口愈合的方法
JP6539652B2 (ja) 2013-12-12 2019-07-03 コンベンタス オーソピディックス， インコーポレイテッド 組織変位ツールおよび方法
US10900039B2 (en) 2014-09-05 2021-01-26 Phio Pharmaceuticals Corp. Methods for treating aging and skin disorders using nucleic acids targeting Tyr or MMP1
CN109069559A (zh) * 2016-04-14 2018-12-21 崔泽尔有限公司 病毒载体稳定化
US12544344B2 (en) 2017-04-19 2026-02-10 Phio Pharmaceuticals Corp. Topical delivery of nucleic acid compounds
US10918426B2 (en) 2017-07-04 2021-02-16 Conventus Orthopaedics, Inc. Apparatus and methods for treatment of a bone

Citations (1)

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US20020111304A1 (en) * 2000-12-01 2002-08-15 Andrius Kazlauskas Methods and compositions for treating fibrotic diseases

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Also Published As

Publication number Publication date
AU2004293474A1 (en) 2005-06-09
ZA200604147B (en) 2007-11-28
KR20060127414A (ko) 2006-12-12
CN101507822A (zh) 2009-08-19
US20090142397A1 (en) 2009-06-04
EP1692154A4 (en) 2009-07-08
US7465442B2 (en) 2008-12-16
IL175603A0 (en) 2006-09-05
CN1906205A (zh) 2007-01-31
CA2546287C (en) 2014-04-22
JP4842139B2 (ja) 2011-12-21
KR101167330B1 (ko) 2012-07-23
JP2011207912A (ja) 2011-10-20
US20110129534A1 (en) 2011-06-02
NO20062978L (no) 2006-06-26
JP2007512377A (ja) 2007-05-17
IL175603A (en) 2011-02-28
EP1692154A1 (en) 2006-08-23
BRPI0416920A (pt) 2007-01-23
US8329671B2 (en) 2012-12-11
WO2005051971A1 (en) 2005-06-09
NZ546983A (en) 2009-05-31
CN100482674C (zh) 2009-04-29
CA2546287A1 (en) 2005-06-09
AU2004293474B2 (en) 2010-12-23
US20050271623A1 (en) 2005-12-08

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Granted publication date: 20120606

Termination date: 20161123