CN101501207B - 合成基因组 - Google Patents

合成基因组 Download PDF

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Publication number
CN101501207B
CN101501207B CN200680052444.3A CN200680052444A CN101501207B CN 101501207 B CN101501207 B CN 101501207B CN 200680052444 A CN200680052444 A CN 200680052444A CN 101501207 B CN101501207 B CN 101501207B
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expression cassette
genome
synthetic
gene group
nucleic acid
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CN101501207A (zh
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J·克雷格·文特尔
汉密尔顿·O·史密斯
克莱德·A·哈奇森三世
丹尼尔·G·吉布森
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Viridos Inc
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Synthetic Genomics Inc
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1093General methods of preparing gene libraries, not provided for in other subgroups
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease

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  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN200680052444.3A 2005-12-06 2006-12-06 合成基因组 Active CN101501207B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74254205P 2005-12-06 2005-12-06
US60/742,542 2005-12-06
PCT/US2006/046803 WO2008024129A2 (en) 2005-12-06 2006-12-06 Synthetic genomes

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CN101501207A CN101501207A (zh) 2009-08-05
CN101501207B true CN101501207B (zh) 2014-03-12

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US (2) US10041060B2 (enExample)
EP (1) EP1968994B1 (enExample)
JP (1) JP5106412B2 (enExample)
CN (1) CN101501207B (enExample)
AU (1) AU2006347573B2 (enExample)
CA (1) CA2643356A1 (enExample)
DK (1) DK1968994T3 (enExample)
IL (1) IL192041A (enExample)
WO (1) WO2008024129A2 (enExample)

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US10093552B2 (en) 2008-02-22 2018-10-09 James Weifu Lee Photovoltaic panel-interfaced solar-greenhouse distillation systems
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EP2998402A1 (en) 2008-10-17 2016-03-23 Joule Unlimited Technologies, Inc. Ethanol production by microorganisms
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US7794969B1 (en) 2009-07-09 2010-09-14 Joule Unlimited, Inc. Methods and compositions for the recombinant biosynthesis of n-alkanes
US20120077251A1 (en) 2010-09-14 2012-03-29 C/O Joule Unlimited Technologies, Inc. Methods and Compositions for Targeting Heterologous Integral Membrane Proteins to the Cyanobacterial Plasma Membrane
WO2011038134A1 (en) 2009-09-25 2011-03-31 Ls9, Inc. Production of fatty acid derivatives
US20110269119A1 (en) 2009-10-30 2011-11-03 Synthetic Genomics, Inc. Encoding text into nucleic acid sequences
MX2012005069A (es) * 2009-10-30 2012-07-17 Synthetic Genomics Inc Codificar texto hacia secuencias de acido nucleico.
CN102939380A (zh) * 2010-03-05 2013-02-20 合成基因组股份有限公司 用于克隆和操作基因组的方法
GB2481425A (en) 2010-06-23 2011-12-28 Iti Scotland Ltd Method and device for assembling polynucleic acid sequences
US8349587B2 (en) 2011-10-31 2013-01-08 Ginkgo Bioworks, Inc. Methods and systems for chemoautotrophic production of organic compounds
US8790901B2 (en) 2011-12-14 2014-07-29 Pronutria, Inc. Microorganisms and methods for producing unsaturated fatty acids
HK1206765A1 (en) 2012-03-26 2016-01-15 Axcella Health Inc. Nutritive fragments, proteins and methods
SG10201604464SA (en) 2012-03-26 2016-07-28 Axcella Health Inc Charged nutritive proteins and methods
HK1206764A1 (en) 2012-03-26 2016-01-15 Axcella Health Inc. Nutritive proteins and methods
EP2831102A4 (en) 2012-03-26 2015-12-02 Pronutria Inc NUTRITIONAL FRAGMENTS, PROTEINS THEREFOR AND METHOD
GB201219989D0 (en) 2012-11-06 2012-12-19 Discuva Ltd Bacterial engineering
WO2014089436A1 (en) 2012-12-07 2014-06-12 Ginkgo Bioworks, Inc. Methods and systems for methylotrophic production of organic compounds
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
WO2015048334A2 (en) 2013-09-25 2015-04-02 Pronutria, Inc. Edible species nutritive polypeptides and methods of production and use thereof
WO2015048339A2 (en) 2013-09-25 2015-04-02 Pronutria, Inc. Compositions and formulations for non-human nutrition and methods of production and use thereof
WO2015054507A1 (en) 2013-10-10 2015-04-16 Pronutria, Inc. Nutritive polypeptide production systems, and methods of manufacture and use thereof
GB201413202D0 (en) 2014-07-25 2014-09-10 Discuva Ltd Process for producing bacterial mutants
EP3430133A1 (en) 2016-03-17 2019-01-23 INVISTA Textiles (U.K.) Limited Carboxylic acid reductase polypeptides and variants having improved activity, materials and processes relating thereto
US11085037B2 (en) * 2016-03-23 2021-08-10 Codex Dna, Inc. Generation of synthetic genomes
CN110494566A (zh) 2017-02-02 2019-11-22 嘉吉公司 产生c6-c10脂肪酸衍生物的经遗传修饰的细胞
EP3775182A1 (en) 2018-03-30 2021-02-17 INVISTA Textiles (U.K.) Limited Materials and methods for biosynthetic manufacture of pimelic acid and utilization of synthetic polypeptides
EP3775242A1 (en) 2018-03-30 2021-02-17 INVISTA Textiles (U.K.) Limited High hydrogen utilization and gas recycle
EP3775240A1 (en) 2018-03-30 2021-02-17 INVISTA Textiles (U.K.) Limited Method for controlling dissolved oxygen concentration in a continuous aerobic fermentation
US11512276B2 (en) 2018-03-30 2022-11-29 Inv Nylon Chemicals Americas, Llc Methods for controlling oxygen concentration during aerobic biosynthesis
WO2019213033A1 (en) 2018-05-02 2019-11-07 Invista North America S.A.R.L. Materials and methods for maximizing biosynthesis through alteration of pyruvate-acetyl-coa-tca balance in species of the genera ralstonia and cupriavidus and organisms related thereto
EP3788156A1 (en) 2018-05-02 2021-03-10 INVISTA Textiles (U.K.) Limited Methods for controlling limitation conditions in product biosynthesis for non-phb generating cupriavidus or ralstonia

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Also Published As

Publication number Publication date
EP1968994B1 (en) 2013-07-03
EP1968994A2 (en) 2008-09-17
IL192041A0 (en) 2008-12-29
WO2008024129A2 (en) 2008-02-28
US20070264688A1 (en) 2007-11-15
US10041060B2 (en) 2018-08-07
JP5106412B2 (ja) 2012-12-26
US20180340165A1 (en) 2018-11-29
JP2009518038A (ja) 2009-05-07
DK1968994T3 (da) 2013-09-30
CN101501207A (zh) 2009-08-05
CA2643356A1 (en) 2008-02-28
AU2006347573B2 (en) 2013-01-17
EP1968994A4 (en) 2009-04-08
WO2008024129A3 (en) 2008-10-09
AU2006347573A1 (en) 2008-02-28
IL192041A (en) 2013-08-29

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