CN101473041B - He4与其它生化标记物在评估子宫内膜癌和子宫癌中的应用 - Google Patents

He4与其它生化标记物在评估子宫内膜癌和子宫癌中的应用 Download PDF

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Publication number
CN101473041B
CN101473041B CN200780007052.XA CN200780007052A CN101473041B CN 101473041 B CN101473041 B CN 101473041B CN 200780007052 A CN200780007052 A CN 200780007052A CN 101473041 B CN101473041 B CN 101473041B
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patient
polypeptide
he4a
expression
endometrial cancer
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Chinese (zh)
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CN101473041A (zh
Inventor
理查德·摩尔
伊丽莎白·萨默斯
杰弗里·W·阿拉德
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Fujirebio America Inc
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Fujirebio America Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5755—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the uterine cervix, uterine corpus or endometrium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57545—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the ovaries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Genetics & Genomics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biophysics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
CN200780007052.XA 2006-01-04 2007-01-04 He4与其它生化标记物在评估子宫内膜癌和子宫癌中的应用 Active CN101473041B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75613106P 2006-01-04 2006-01-04
US60/756,131 2006-01-04
PCT/US2007/000215 WO2007081767A2 (en) 2006-01-04 2007-01-04 Use of he4 and other biochemical markers for assessment of endometrial and uterine cancers

Publications (2)

Publication Number Publication Date
CN101473041A CN101473041A (zh) 2009-07-01
CN101473041B true CN101473041B (zh) 2017-11-14

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ID=38256906

Family Applications (3)

Application Number Title Priority Date Filing Date
CN200780007052.XA Active CN101473041B (zh) 2006-01-04 2007-01-04 He4与其它生化标记物在评估子宫内膜癌和子宫癌中的应用
CN200780007130.6A Active CN101460630B (zh) 2006-01-04 2007-01-04 He4与其它生化标记物在卵巢癌评估中的应用
CN201610512072.3A Pending CN106124765A (zh) 2006-01-04 2007-01-04 He4与其它生化标记物在卵巢癌评估中的应用

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN200780007130.6A Active CN101460630B (zh) 2006-01-04 2007-01-04 He4与其它生化标记物在卵巢癌评估中的应用
CN201610512072.3A Pending CN106124765A (zh) 2006-01-04 2007-01-04 He4与其它生化标记物在卵巢癌评估中的应用

Country Status (7)

Country Link
US (8) US20080020473A1 (https=)
EP (6) EP2982761B1 (https=)
JP (3) JP5221381B2 (https=)
CN (3) CN101473041B (https=)
ES (2) ES2748397T3 (https=)
PL (1) PL2982761T3 (https=)
WO (2) WO2007081767A2 (https=)

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US10267802B2 (en) 2015-09-23 2019-04-23 The Board Of Trustees Of The Leland Stanford Junior University Methods of prognosis and diagnosis of ovarian cancer
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Publication number Publication date
JP2009521953A (ja) 2009-06-11
EP1969136A4 (en) 2009-04-15
JP5164855B2 (ja) 2013-03-21
EP3026119A1 (en) 2016-06-01
JP5221381B2 (ja) 2013-06-26
US20080020473A1 (en) 2008-01-24
US20200292549A1 (en) 2020-09-17
CN101460630A (zh) 2009-06-17
JP5711196B2 (ja) 2015-04-30
ES2650244T3 (es) 2018-01-17
HK1219514A1 (en) 2017-04-07
WO2007081768A3 (en) 2008-04-24
US20240288434A1 (en) 2024-08-29
US20240133889A1 (en) 2024-04-25
JP2013050457A (ja) 2013-03-14
WO2007081767A2 (en) 2007-07-19
CN101473041A (zh) 2009-07-01
EP2423321A2 (en) 2012-02-29
CN101460630B (zh) 2016-08-10
US20240230652A9 (en) 2024-07-11
EP1969136A2 (en) 2008-09-17
US20200182878A1 (en) 2020-06-11
EP2982761A1 (en) 2016-02-10
WO2007081768A2 (en) 2007-07-19
EP2420576A3 (en) 2012-03-14
US20180156805A1 (en) 2018-06-07
PL2982761T3 (pl) 2018-03-30
EP2423321A3 (en) 2012-03-14
EP2420576A2 (en) 2012-02-22
US20070286865A1 (en) 2007-12-13
JP2009522578A (ja) 2009-06-11
EP2982761B1 (en) 2017-10-04
EP1846768A4 (en) 2009-04-08
EP1846768A2 (en) 2007-10-24
ES2748397T3 (es) 2020-03-16
CN106124765A (zh) 2016-11-16
US20180180620A1 (en) 2018-06-28
WO2007081767A3 (en) 2008-04-24
EP3026119B1 (en) 2019-09-18

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