CN101468097A - Chinese medicinal composition for nourishing liver and kidney, moistening intestines and relaxing piss, preparation and method for preparing the same - Google Patents

Chinese medicinal composition for nourishing liver and kidney, moistening intestines and relaxing piss, preparation and method for preparing the same Download PDF

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CN101468097A
CN101468097A CNA2007103045860A CN200710304586A CN101468097A CN 101468097 A CN101468097 A CN 101468097A CN A2007103045860 A CNA2007103045860 A CN A2007103045860A CN 200710304586 A CN200710304586 A CN 200710304586A CN 101468097 A CN101468097 A CN 101468097A
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kidney
chinese medicine
liver
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CN101468097B (en
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张润琪
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Beijing Qianjiheng Beverage Sales Co., Ltd.
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Beijing Zhangrunqi Medical Research Institute
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Abstract

The invention relates to a traditional Chinese medicine composition for invigorating the liver and the kidney and loosing the bowel to relieve constipation, preparation and preparation method thereof, belonging to the traditional Chinese medicine field, prepared by the following raw material by the following weight parts: prepared rehmannia root 10-60 parts, flgwort 10-20 parts, broomrape 15-30 parts, garden burnet 3-10 parts, mulberrt 10-85 parts, pagodatree flower bud 3-6 parts, cassia seed 1-35 parts. The traditional Chinese medicine composition has obvious constipation-relieving effect and also has the liver and kidney invigorating function. The beverage and preparation of the traditional Chinese medicine composition is convenient for oral administration without side effect and medicine dependence is suitable for child and the elder and for long-time administration.

Description

The Chinese medicine composition of nourishing the liver and kidney loosening bowel to relieve constipation, preparation and preparation method thereof
Technical field
Chinese medicine composition that can nourishing the liver and kidney when the present invention relates to a kind of loosening bowel to relieve constipation, specifically a kind of is the Chinese medicine preparation of feedstock production with the Chinese herbal medicine, the invention still further relates to the preparation method of this Chinese medicine preparation, belongs to the field of Chinese medicines.
Background technology
At present, because the raising of people's living standard, the quickening of live and work rhythm, reason such as diet is irregular, mental pressure is excessive, the appearance constipation symptom that most of people are light or heavy.The constipation general solution be interpreted as be hard and dry stiff undesired and drain the symptom of difficulty.From medical angle, constipation is not a kind of concrete disease, but a symptom of multiple disease.More particularly, constipation is that defecation frequency obviously reduces, and per 2~3 days or longer time, once irregular, excrement matter was stiff, often with the pathological phenomenon of difficult defecation sense.Constipation can be divided into acute and chronic two classes.Acute constipation is caused by acute illnesss such as intestinal obstruction, enteroparalysis, acute peritonitis, cerebrovascular accidents; The chronic constipation cause of disease is complicated, but general non-evident sympton.Press site of pathological change classification, can be divided into two kinds: 1. colonic constipation.Because the constipation that the inside and outside mechanical obstruction of colon causes is referred to as the mechanicalness constipation.Because the constipation that colonic peristalsis miopragia or forfeiture cause is referred to as senile constipation.Because the constipation that the intestinal smooth muscle spasm causes is referred to as spastic constipation.2. proctogenous constipation.Because mucous membrane of rectum sensor sensitivity weakens and causes the excrement piece to be piled up at rectum.See rectal cancer, perianal etc.
Prolonged constipation can not get Drug therapy can cause serious harm to human body.Because prolonged constipation can seriously hinder the human body toxin expelling.Even can can't go into a coma even death by toxin expelling because of prolonged constipation.Ordinary person's food enters gastrointestinal, and through digestion, absorb the most at last residue and become feces and excreted about needs 24~48 hours, generally be 1~2 day twice stool blanking time.If because some reason makes feces of a specified duration excessively in the big enteral time of staying, moisture contained in the feces is by excessive absorption, the feces dry, hard that becomes, with time lengthening, be difficult to discharge rectal tenesmus, pain during defecation, or abdominal distention, stomachache, many wind, inappetence, dizzy symptom such as weak have been caused, normal defecation rule is upset, and defecation frequency reduces, and prolong blanking time, the stool that severe patient is discharged is the pellet shapes graininess as sheep dung sample.If defecation frequency is less than 3 times weekly, and accompany obvious difficult defecation, this situation just can be defined as constipation.
The old people is more common in constipation, can divide constipation of colon and proctogenous constipation.Because how unsound old people's tooth is, the low meticulous diet of slag is eaten in happiness, thereby lacks the stimulation of cellulose to intestinal wall, makes the time lengthening of colon running feces; The old people moves and lacks in addition, and the myenteron contractility generally descends, and all easily facilitates constipation of colon.Old people's levator ani and anal sphincter are lax unable, cause fecal impaction to form proctogenous constipation in rectal sinuses.
The treatment means commonly used that is directed to constipation at present has the branch of external preparation and oral preparations.External preparation commonly used is a glycerin, but it cures the symptoms, not the disease, can only short term relief constipation symptom, in case stop using, the constipation symptom exists.
Medicine for oral administration at constipation, major part all contains diarrheal effectiveness, after constipation patient is taken, cause diarrhoea in short time, though constipation transference cure outwardly, but these medicines are taken for a long time drug dependence are not only taken place easily the equal toxic side effect of human body, the serious enterokinesia Disability that causes.Also have the part patient strong,, health is had great harm repeatedly being easy to cause the health dehydration after the diarrhoea to this kind drug susceptibility.
Therefore, be badly in need of a kind of having no side effect at present, can fundamentally improve gastrointestinal function, really play the pharmaceutical preparation of loosening bowel to relieve constipation effectiveness.
Summary of the invention
To sum up, people to good effect, have no side effect, still there is demand in the medicine that can play tonic effect at loosening bowel to relieve constipation, when regulating the intestines and stomach, up to now, does not also find any report about pharmaceutical composition of the present invention.Inventor Zhang Runqi doctor is engaged in tcm clinical practice, research cause four more than ten years.Teacher of the taking part in Taoism is in the quite high traditional Chinese medical science well-known doctor Li Zheng doctor's of public praise self-passing at first, in the near future, eager to learn because of natural endowment, smart diligent tireless, and be subjected to liking of well-known doctor old docter of TCM doctor Su Zhixuan among the people (" reviving one time " doctor Lao Su that common people's public praise is widely read), and formally receive and be disciple, from then on master and apprentice two people are together morning and night, learn and pass on the art industry, moral becomes skill smart, and teacher people and clay figurine are not doublely got the chief.Study repeatedly through the inventor, and the clinical verification by for many years, having found finally has the loosening bowel to relieve constipation of this better curative effect Chinese medicine composition, thereby has finished the present invention.Prescription is that the inventor uses the traditional diseases prevention of Chinese medicine, the mechanism of curing the disease is clinical through what accumulate over a long period for many years with theory and himself, face the disease experience, the connection between theory and practice, and sum up with him " ascending, descending, exiting and entering; move smooth and easy; gastric qi is gentle; the healthy energy internal memory; heresy can not be done; " medical knowledge be to instruct the Chinese medicine technology of thinking and his exquisiteness, join this side of marrow, beverage preparation of the present invention with dietetic therapy for medication, satisfy in the process of daily drinking-water demand people, effectively prevented, treatment, help healthy population fundamentally to keep the purpose of normal defecation on ordinary days, and with the effect of nourishing the liver and kidney.
The object of the present invention is to provide a kind of nourishing the liver and kidney effect of relaxing bowel remarkable, and human body is had no side effect, simultaneously also can liver heat removing item, the blood pressure lowering of dispeling the wind, blood fat reducing, the Chinese medicine composition that relieves inflammation or internal heat.
Another object of the present invention is to provide the preparation that contains above-mentioned nourishing the liver and kidney loosening bowel to relieve constipation Chinese medicine composition.
A further object of the present invention provides a kind of preparation method of nourishing the liver and kidney loosening bowel to relieve constipation Chinese medicinal composition preparation.
For achieving the above object, the present invention adopts following technical scheme:
The present invention selects Radix Rehmanniae Preparata, Radix Scrophulariae, Herba Cistanches, Radix Sanguisorbae, Fructus Mori, the Flos Sophorae Immaturus, Semen Cassiae, and totally 7 flavor medicines make up, and make each medicine produce synergism these drug regimens, thereby can effectively play the effect of loosening bowel to relieve constipation.
It is irregular sheet, fragment the Radix Rehmanniae Preparata of wherein selecting for use (RADIX REHMANNIAE PREPARATA), and size, thickness differ.The surface corvinus, glossy, stickiness is big.Soft and the band toughness of matter, frangibility not, the section corvinus, glossy.Odorless, it is sweet to distinguish the flavor of.Sweet, tepor.Return liver, kidney channel.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Be used for the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair.
Radix Scrophulariae (RADIX SCROPHULARIAE) its to be class cylindrical, the centre is slightly thick or upper coarse and lower fine, the microbend that has, long 6~20cm, diameter 1~3cm.Surface lark or taupe have irregular longitudinal furrow, horizontal hole skin and sparse transverse crack and mark of fibrous root.Sweet, bitter, salty, be slightly cold.Return lung, stomach, kidney channel.Has the removing heat from blood YIN nourishing, the effect of eliminating fire and detoxication.Be used for consumption of YIN caused by febrile disease, the crimson tongue excessive thirst, maculae caused by violent heat pathogen, constipation is hindered in Tianjin, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.
It is oblate cylindricality Herba Cistanches (HERBA CISTANCHES), and is crooked slightly, long 3~15cm, diameter 2~8cm.Surface sepia or taupe brown, the close fleshly scale leaf of being arranged by imbricate, the scale leaf tip is disconnected usually, body weight, matter is hard, and little have a flexibility, frangibility not, the section sepia has light brown point-like vascular bundle, is arranged in wavy ring grain.Feeble QI, sweet, little hardship of distinguishing the flavor of.Sweet, salty, temperature.Return kidney, large intestine channel.Has kidney-replenishing, benefiting essence-blood, the effect of loosening bowel to relieve constipation.Be used for sexual impotence, infertile, soreness of the waist and knees, muscles and bones is unable, the dryness of the intestine constipation.
It is irregular spindle or cylindrical Radix Sanguisorbae (RADIX SANGUISORBAE), crooked slightly or distortion, long 5~25cm, diameter 0.5~2cm.Surface taupe, sepia or mulberry, coarse, vertical wrinkle, transverse crack and supporting root trace are arranged.Matter is hard, and there is numerous yellow-whites in the more smooth or skin zone of section to the continuous shape fiber of yellowish-brown, and woody part yellow or yellowish-brown slightly are radial arrangement.Section is irregular cycle or ellipse, thick 0.2~0.5cm; Tangent plane aubergine or sepia.Odorless, mildly bitter flavor is puckery.Bitter, acid, puckery are slightly cold.Return liver, large intestine channel.Have cooling blood for hemostasis, the effect of skin ulcer is held back in detoxifcation.Be used to have blood in stool hemorrhoidal bleeding, dysentery, metrorrhagia, burn due to hot liquid or fire, carbuncle sore tumefacting virus.
It is collective fruit for a Fructus Mori (FRUCTUS MORI), is formed by the little achene set of majority, is Long Circle, long 1~2cm, diameter 0.5~0.8cm.Yellowish-brown, brownish red have short infructescence stalk to mulberry.Little achene oval, flat slightly, be about 2mm, wide about 1mm, 4 pieces of outer tool meat tapels.Feeble QI, the little acid and sweet of distinguishing the flavor of.Sweet, sour, cold.GUIXIN, liver, kidney channel.Has the YIN nourishing of enriching blood, the effect of promoting the production of body fluid and moisturizing.Be used for vertigo and tinnitus, palpitation and insomnia, early whitening of beard and hair, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, blood deficiency and constipation.
The flowers are in blossom summer puts or alabastrum is gathered when forming for Flos Sophorae for the Flos Sophorae Immaturus (FLOS SOPHORAE), in time dry, removes debranching, stalk and impurity.It is avette or oval that the Flos Sophorae Immaturus is, long 2~6mm, the about 2mm of diameter.Several longitudinal grins are arranged at the calyx bottom.The top of calyx is the unopened petal of yellow-white.Bennet is tiny.Body is light, and hands is twisted with the fingers promptly broken.Odorless, mildly bitter flavor is puckery.Hardship is slightly cold.Return liver, large intestine channel.Has cooling blood for hemostasis, the effect of purging liver-fire.Be used to have blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia is spitted blood, epistaxis, the liver-heat conjunctival congestion, it is dizzy to have a headache.
Semen Cassiae (SEMEN CASSIAE) slightly is the square or short cylindrical shape of rib, two ends parallel oblique, long 3~7mm, wide 2~4mm.The green brown or burgundy in surface, smoothly glossy.One end is more smooth, and end is tiltedly sharp in addition, and dorsal ventral side respectively has the crest line of 1 projection, and respectively there is 1 oblique symmetry the crest line both sides and the more shallow linear dimpled grain of color.Matter is hard, is difficult for broken.It is thin to plant skin, cotyledon 2, and yellow is serpentine warpage and overlapping.Feeble QI, mildly bitter flavor.Sweet, bitter, salty, be slightly cold.Return liver, large intestine channel.Has clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.Be used for the puckery pain of conjunctival congestion, the many tears of photophobia, it is dizzy to have a headache, poor vision, constipation.
The consumption of each drug component of the present invention also is that the inventor draws through groping in a large number to sum up, and each is organized consumption and all have better curative effect in the following weight parts ratio range.
The concrete technical scheme of the present invention is:
A kind of Chinese medicine composition of nourishing the liver and kidney loosening bowel to relieve constipation, it is to be made by following raw materials in weight portion medicine: 10~60 parts of Radix Rehmanniae Preparata, 10~20 parts of Radix Scrophulariaes, 15~30 parts of Herba Cistanches, 3~10 parts of Radix Sanguisorbaes, 10~85 parts in Fructus Mori, 3~6 parts of the Flos Sophorae Immaturus, 1~35 part of Semen Cassiae.
The Chinese medicine composition of above-mentioned a kind of nourishing the liver and kidney loosening bowel to relieve constipation, the preferable weight portion proportioning of its crude drug is: 15~55 parts of Radix Rehmanniae Preparata, 12~18 parts of Radix Scrophulariaes, 20~25 parts of Herba Cistanches, 5~8 parts of Radix Sanguisorbaes, 25~60 parts in Fructus Mori, 3~5 parts of the Flos Sophorae Immaturus, 2~25 parts of Semen Cassiaes.
A kind of Chinese medicine preparation of nourishing the liver and kidney loosening bowel to relieve constipation, its Chinese medicine composition and pharmaceutics acceptable auxiliary by above-mentioned nourishing the liver and kidney loosening bowel to relieve constipation is formed.
Can be according to known method in the pharmaceuticals industry, aforementioned pharmaceutical compositions is made various peroral dosage form after by the known method degerming.
According to the route of administration difference, Chinese medicine composition of the present invention is made can only oral formulations, as decoction, oral liquid, granule, tablet, sweet mastic, honeydew body, capsule etc.
Preferred dosage form of the present invention is a peroral dosage form, and best peroral dosage form is a decoction.Prepare the method for nourishing the liver and kidney loosening bowel to relieve constipation Chinese medicine decoction of the present invention, concrete steps are:
(1) by claim 1 or 2 weight portion proportioning weighting raw materials;
(2) in crude drug, add 3 times of water gagings, soaked 20~30 minutes;
(3) back that is fried boiling kept fluidized state 10~15 minutes, taking liquid;
(4) add 3 times of water gagings, the back that is fried boiling kept fluidized state 10~15 minutes, taking liquid;
(5) twice medicinal liquid mixing promptly made decoction stock solution.
The best approach kept fluidized state 10~15 minutes, taking liquid for the back slow fire that is fried boiling with high heat in above-mentioned steps (3) and (5);
Above-mentioned a kind of preparation method for preparing nourishing the liver and kidney loosening bowel to relieve constipation Chinese medicine decoction adds the field of beverage acceptable auxiliary after the dilution of the decoction stock solution of preparing interpolation water and makes beverage.
Above-mentioned a kind of preparation method for preparing nourishing the liver and kidney loosening bowel to relieve constipation Chinese medicine decoction, the dilution ratio of described decoction stock solution and water is 1:6~12.
Above-mentioned a kind of preparation method for preparing nourishing the liver and kidney loosening bowel to relieve constipation Chinese medicine decoction, described acceptable auxiliary is a fruice natural juice.
The present invention also can make the Sugarless type beverage that is fit to the diabetes patient with according to actual needs, and its batching is equipped with sugar-free beverage adjuvant commonly used for Chinese medicine composition decoction of the present invention.
The present invention also can adopt the conventional preparation method of the field of Chinese medicines to be prepared into other peroral dosage forms, as with crude drug grind into powder mix homogeneously, makes powder, uses mixing in water for oral taking.Raw material liquid medicine is carried, and the condensed water decocting liquid is made oral liquid.Also can concentrate and make clear paste, add adjuvant and make sweet mastic (soft extract) etc.
Usage of the present invention and consumption:
Decoction of the present invention or beverage are the oral way administration, every day twice, sooner or later each once, one time 300 milliliters.
Advantage of the present invention and benefit: medical knowledge of the present invention for " ascending, descending, exiting and entering, operation is smooth and easy, gastric qi is gentle, healthy energy internal memory, heresy can not do " be utilization Chinese medicine traditional diseases prevention, the mechanism of curing the disease and theory and inventor for many years clinical, face the disease experience, the summary of combining theory and practice together draws.The present invention can effectively play the effect of loosening bowel to relieve constipation, and without any side effects, also has the effect of nourishing the liver and kidney, blood fat reducing, heat-clearing and toxic substances removing simultaneously.Chinese medicine composition of the present invention is made beverage to be taken, mouthfeel makes that well people are easy to accept, and with dietetic therapy for medication, in the process that satisfies the daily drinking-water demand of people, effectively arrived prevention, treatment, help healthy population and fundamentally kept the purpose of normal defecation on ordinary days.Because the present invention is without any side effects, takes no drug dependence for a long time, therefore same suitable child and old man take.The crowd of being suitable for is extensive.The present invention is different from the existing side that moisturizes, and do not have the relieving constipation medicine of the method that kidney tonifying enriches blood, the present invention when improving gastrointestinal function with nourishing the liver and kidney, the effect of supplementing fluid to relax the bowels, fundamentally solve this puzzlement of constipation, help people to reach and keep the purpose of normal defecation on ordinary days.
The specific embodiment
The used medical material of present embodiment meets 2000 editions one ministerial standards of Pharmacopoeia of People's Republic of China all available from Chinese Medicinal Materials Co.
The preparation of embodiment 1 medicine beverage of the present invention
Preparation method:
(1) by following consumption weighting raw materials;
(2) in crude drug, add 3 times of water gagings, soaked 20~30 minutes;
(3) kept fluidized state 10~15 minutes with slow fire, taking liquid after intense fire is fried boiling;
(4) add 3 times of water gagings, slow fire kept fluidized state 10~15 minutes, taking liquid after intense fire was fried boiling;
(5) twice medicinal liquid mixing promptly made decoction stock solution;
(6) decoction stock solution is added 6 times of water dilution backs and add the seasoning of fruit juice natural juice, promptly make drink agent.
Crude drug and consumption:
55 parts of Radix Rehmanniae Preparata, 12 parts of Radix Scrophulariaes, 23 parts of Herba Cistanches, 8 parts of Radix Sanguisorbaes, 25 parts in Fructus Mori, 3 parts of the Flos Sophorae Immaturus, 22 parts of Semen Cassiaes.
Embodiment 2 sugar-free beverage agent preparations of the present invention
Preparation method:
(1) by following consumption weighting raw materials;
(2) in crude drug, add 3 times of water gagings, soaked 20~30 minutes;
(3) back that is fried boiling kept fluidized state 10~15 minutes, taking liquid;
(4) add 3 times of water gagings, the back that is fried boiling kept fluidized state 10~15 minutes, taking liquid;
(5) twice medicinal liquid mixing promptly made decoction stock solution;
(6) decoction stock solution is added 12 times of water dilution backs and add the sugar-free beverage auxiliary material, promptly make drink agent.
Crude drug and consumption:
15 parts of Radix Rehmanniae Preparata, 18 parts of Radix Scrophulariaes, 20 parts of Herba Cistanches, 5 parts of Radix Sanguisorbaes, 60 parts in Fructus Mori, 5 parts of the Flos Sophorae Immaturus, 25 parts of Semen Cassiaes.
Embodiment 3 medicinal granule preparations of the present invention
Preparation method:
By following consumption weighting raw materials, crude drug of the present invention was soaked 20~30 minutes according to a conventional method, add 3 times of water gagings back that is fried boiling and kept fluidized state 10~15 minutes, taking liquid; Add 3 times of water gagings back that is fried boiling again and kept fluidized state 10~15 minutes, taking liquid; Twice medicinal liquid hybrid filtering is concentrated into relative density 1.3~1.34 thick pastes, spray granulation, drying.Packing.Crude drug and consumption:
40 parts of Radix Rehmanniae Preparata, 16 parts of Radix Scrophulariaes, 25 parts of Herba Cistanches, 7 parts of Radix Sanguisorbaes, 54 parts in Fructus Mori, 4 parts of the Flos Sophorae Immaturus, 2 parts of Semen Cassiaes.
Clinical experiment of the present invention and interpretation of result:
One, clinical data:
1, source of data: totally 48 examples are collected in Beijing Zhangrunqi Medical Research Institute.
2, the age: between 18-82 years old, male's 18 examples wherein, women's 30 examples.
Two, choice criteria: the plain body deficiency of YIN, or surfeit is pungent, or puerperal, reason such as blood deficiency caused constipation, and healthy usually, habitual constipation is more than 1-3 years, on ordinary days constipation with dry stool, about 3~4 days once, vexed often irritability, sleep difference and with two quasi-representative cases of the soreness of waist.Through examining: red tongue, yellow and thin fur, thready and rapid pulse, be diagnosed as: the constipation of deficiency of the kidney yin type.
Three, Therapeutic Method:
1, treatment group 1: select patient's 12 examples at random, the drink agent of the oral embodiment of the invention 1 preparation 15 days, 1 month, 2 months; Twice/day, 300 milliliters/time, early, the evening each 1 time.
2, treatment group 2: select patient's 12 examples at random, the sugar-free beverage agent of the oral embodiment of the invention 2 preparations 15 days, 1 month, 2 months; Twice/day, 300 milliliters/time, early, the evening each 1 time.
3, treatment group 3: select patient's 12 examples at random, the granule of the oral embodiment of the invention 3 preparations 15 days, 1 month, 2 months; Twice/day, early, the evening each 1 time, boiled water is taken after mixing it with water.
4, the blank group 4: select patient's 12 examples at random, oral blank placebo 15 days, 1 month, 2 months; Twice/day, early, the evening each 1 time, boiled water is taken after mixing it with water.
Four, criterion of therapeutical effect:
(1) recovery from illness:
(1): the patient's readme after oral 15 days: symptoms such as the conscious soreness of waist of patient all disappear.Simultaneously conscious just soft, once a day.
(2): continue oral 1 month patient's readme: symptoms such as the conscious constipation and the soreness of waist all disappear, and every day is defecation on time.
(3): continue oral 2 months patient's readme: symptoms such as the conscious constipation and the soreness of waist all disappear, and every day is defecation on time.
(2) effective:
(1): the patient's readme after oral 15 days: the symptom of the conscious sleep quality and the soreness of waist before has clear improvement, and is just soft, once a day.
(2): oral 1 month patient's readme: conscious sleep quality be improved significantly, symptoms such as the soreness of waist disappear substantially, simultaneously conscious just soft, every day is defecation on time.
(3): oral 2 months patient's readme: conscious sleep quality be improved significantly, symptoms such as the soreness of waist disappear substantially, simultaneously conscious just soft, every day is defecation on time.
(3) invalid:
(1) oral 15 days: patient's readme had no significant change.
(2) continue oral 1-2 month: patient's readme has no significant change.
Five, clinical practice result and analysis:
Among the therapeutic outcome 48 routine patients, treatment group 1 recovery from illness 8 examples, effective 3 examples, invalid 1 example, effectively reaching cure rate is 91.7%.Treatment group 2 recoveries from illness 9 examples, effective 3 examples, invalid 0 example, effectively reaching cure rate is 100%.Treatment group 3 recoveries from illness 9 examples, effective 2 examples, invalid 1 example, effectively reaching cure rate is 91.7%.Blank group 4 recoveries from illness 0 example, effective 2 examples, invalid 10 examples, effectively reaching cure rate is 1.67%.And without any side effects and drug dependence generation in whole therapeutic process.
The Chinese medicine composition of above-mentioned clinical experiment presentation of results nourishing the liver and kidney loosening bowel to relieve constipation of the present invention is compared the curative effect with good loosening bowel to relieve constipation with matched group, effectively reach cure rate up to 91.7%~100%.The result it can also be seen that from clinical experiment, and the present invention is simultaneously with the effect of good nourishing the liver and kidney, and without any side effects to human body.

Claims (9)

1, a kind of Chinese medicine composition of nourishing the liver and kidney loosening bowel to relieve constipation is characterized in that, it is to be made by following raw materials in weight portion medicine:
10~60 parts of Radix Rehmanniae Preparata, 10~20 parts of Radix Scrophulariaes, 15~30 parts of Herba Cistanches, 3~10 parts of Radix Sanguisorbaes, 10~85 parts in Fructus Mori, 3~6 parts of the Flos Sophorae Immaturus, 1~35 part of Semen Cassiae.
2, the Chinese medicine composition of a kind of nourishing the liver and kidney loosening bowel to relieve constipation according to claim 1 is characterized in that, it is to be made by following raw materials in weight portion medicine:
15~55 parts of Radix Rehmanniae Preparata, 12~18 parts of Radix Scrophulariaes, 20~25 parts of Herba Cistanches, 5~8 parts of Radix Sanguisorbaes, 25~60 parts in Fructus Mori, 3~5 parts of the Flos Sophorae Immaturus, 2~25 parts of Semen Cassiaes.
3, a kind of Chinese medicine preparation of nourishing the liver and kidney loosening bowel to relieve constipation is characterized in that, is made up of the Chinese medicine composition and the pharmaceutics acceptable auxiliary of claim 1 or 2 described loosening bowel to relieve constipation.
4, the Chinese medicine preparation of a kind of nourishing the liver and kidney loosening bowel to relieve constipation according to claim 3 is characterized in that, described dosage form is a peroral dosage form.
5, the Chinese medicine preparation of a kind of nourishing the liver and kidney loosening bowel to relieve constipation according to claim 4 is characterized in that, described peroral dosage form is decoction, oral liquid, granule, tablet, sweet mastic, honeydew body, capsule.
6, a kind of preparation method for preparing nourishing the liver and kidney loosening bowel to relieve constipation Chinese medicine decoction is characterized in that, its concrete steps are as follows:
(1) by claim 1 or 2 weight portion proportioning weighting raw materials;
(2) in crude drug, add 3 times of water gagings, soaked 20~30 minutes;
(3) back that is fried boiling kept fluidized state 10~15 minutes, taking liquid;
(4) add 3 times of water gagings, the back that is fried boiling kept fluidized state 10~15 minutes, taking liquid;
(5) twice medicinal liquid mixing promptly made decoction stock solution.
7, a kind of preparation method for preparing nourishing the liver and kidney loosening bowel to relieve constipation Chinese medicine decoction according to claim 6 is characterized in that, adds the field of beverage acceptable auxiliary after the decoction stock solution interpolation water dilution of preparing and makes beverage.
8, a kind of preparation method for preparing nourishing the liver and kidney loosening bowel to relieve constipation Chinese medicine decoction according to claim 7, the dilution ratio that it is characterized in that described decoction stock solution and water is 1:6~12.
9, a kind of preparation method for preparing nourishing the liver and kidney loosening bowel to relieve constipation Chinese medicine decoction according to claim 7 is characterized in that described acceptable auxiliary is a fruice natural juice.
CN2007103045860A 2007-12-28 2007-12-28 Chinese medicinal composition for nourishing liver and kidney, moistening intestines and relaxing piss, preparation and method for preparing the same Expired - Fee Related CN101468097B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103416808A (en) * 2013-07-10 2013-12-04 安徽福顺食品有限公司 Beverage with juicy peach flavor for relaxing bowel and preparation method thereof
CN104784457A (en) * 2015-03-17 2015-07-22 北京千基恒饮料销售有限公司 Beverage product for nourishing lung and kidney, moistening intestines and facilitating feces excretion and preparation method thereof
CN106418151A (en) * 2016-09-29 2017-02-22 广西南宁乐蕊生物科技有限责任公司 Nutritional power capable of relaxing bowels

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1056530C (en) * 1997-08-29 2000-09-20 刘进成 Chinese medicinal herb composition for treating habitual oppilation

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103416808A (en) * 2013-07-10 2013-12-04 安徽福顺食品有限公司 Beverage with juicy peach flavor for relaxing bowel and preparation method thereof
CN103416808B (en) * 2013-07-10 2016-02-10 安徽福顺食品有限公司 A kind of juicy peach beverage relaxed bowel and preparation method thereof
CN104784457A (en) * 2015-03-17 2015-07-22 北京千基恒饮料销售有限公司 Beverage product for nourishing lung and kidney, moistening intestines and facilitating feces excretion and preparation method thereof
CN106418151A (en) * 2016-09-29 2017-02-22 广西南宁乐蕊生物科技有限责任公司 Nutritional power capable of relaxing bowels

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