CN101439064B - Nourishing tonic for sport - Google Patents
Nourishing tonic for sport Download PDFInfo
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- CN101439064B CN101439064B CN2008102403961A CN200810240396A CN101439064B CN 101439064 B CN101439064 B CN 101439064B CN 2008102403961 A CN2008102403961 A CN 2008102403961A CN 200810240396 A CN200810240396 A CN 200810240396A CN 101439064 B CN101439064 B CN 101439064B
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- radix
- acanthopanacis senticosi
- caulis acanthopanacis
- octacosanol
- sport
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Abstract
The invention relates to a sports nutritional supplement, the main components of which include acanthopanax extract and octocosanol. The sports nutritional supplement has the functions of promoting hepatin synthesizing, increasing resistance and recovering physical fitness and is particularly suitable for athletes.
Description
Technical field
The invention belongs to the sport nutrition technical field, be specifically related to a kind of can stamina intensifying, recover the bodily exercises nutritional supplement.
Background technology
The athlete must bear the training of large amount of exercise and big intensity continuously, and the recovery after this training becomes the training period key that is accomplished of task.The athlete will guarantee to get the hang of with good physical ability after the training, promotes that glycogen is synthetic, stamina intensifying, recovery physical ability just have very realistic meanings.
Radix Et Caulis Acanthopanacis Senticosi is dry rhizome and the root of Araliaceae (Araliaceae) plant Radix Et Caulis Acanthopanacis Senticosi Acanthopanax senticosus (Rupr.etMaxim.) Harms.syn.EleutherococccusSenticosus (Rupr.etMaxim.) Maxim..Radix Et Caulis Acanthopanacis Senticosi is shown in Shennong's Herbal the earliest, classifies as top grade.Commodity are called Radix Acanthopanacis Senticosi, and former main product is in the mountain area, Heilongjiang Province, and local popular name is practised and claimed " tiger is hasty and careless ", then is called the smooth slender acanthopanax of shrimp in Japan, and is called Siberian ginseng in the former Soviet Union.Radix Et Caulis Acanthopanacis Senticosi acrid in the mouth, little hardship, warm in nature, nontoxic.Radix Et Caulis Acanthopanacis Senticosi has good replenishing QI to invigorate the spleen is arranged, the effect of tonifying the kidney for tranquilization, cures mainly that soreness of the waist and knees, body void are weak, insomnia, dreaminess, inappetence.Shennong's Herbal mentions that the earliest Radix Et Caulis Acanthopanacis Senticosi has hard muscles and bones; Strong will is obeyed the anti-old effectiveness of making light of one's life by commiting suicide for a long time, payes attention to but obtain the descendant; Mention that until European medical journals in 1980 continent, the athlete of the former Soviet Union take Radix Et Caulis Acanthopanacis Senticosi with after improving endurance and exempting anxiety, the beginning is obtained global sport and payes attention to.
Octacosanol (Ocatacosanol); Claim that again the illiteracy dawn is pure, Sorghum vulgare Pers. is pure; Be the monobasic high fatty alcohol that a kind of pure natural has physiologically active, be white powder or flakey crystal, fusing point 81-83 ℃; Dissolve in organic solvents such as hot ethanol, ether, benzene, toluene, chloroform, dichloromethane, petroleum ether, water insoluble.Doctor cureton of American I llinois university through 20 years to 42 project testings of 894 people, confirm that its main effect is stamina intensifying, energy and muscle power; Improve muscular strength; Improve response time, reflection and acuteness; Cardiac function enhancing; Eliminate myalgia, reduce the muscle friction; Reduce necessary oxygen amount.Octacosanol is a kind of natural resisting fatigue material, has significant resisting fatigue, promotes physical ability, improves human tolerance, improves the metabolism ratio, reduces multiple functions such as necessary oxygen demand and zest hormone.In the U.S., Japan and other countries, octacosanol has been widely used in functional food, various nutrition contribution, medicine, cosmetics, the high-grade feedstuff, and its market share is in continuous expansion.
Radix Et Caulis Acanthopanacis Senticosi relatively is widely used for sports tonica, does not see bibliographical information as yet but Radix Et Caulis Acanthopanacis Senticosi combines octacosanol to be used to improve motor capacity.
Summary of the invention
The object of the present invention is to provide a kind of nourishing tonic for sport, it is synthetic that this nourishing tonic for sport has the glycogen of promotion, stamina intensifying, and the effect that recovers physical ability is particularly suitable for the athlete and eats.
Nourishing tonic for sport provided by the present invention, it contains the component of following weight portion:
Radix Et Caulis Acanthopanacis Senticosi extract 1～50
Octacosanol 1.
Preferably, the component that contains following weight portion:
Radix Et Caulis Acanthopanacis Senticosi extract 1～20
Octacosanol 1.
More preferably, the component that contains following weight portion:
Radix Et Caulis Acanthopanacis Senticosi extract 2～10
Octacosanol 1.
Most preferably, the component that contains following weight portion:
Radix Et Caulis Acanthopanacis Senticosi extract 5
Octacosanol 1.
Wherein, said Radix Et Caulis Acanthopanacis Senticosi extract is the Radix Et Caulis Acanthopanacis Senticosi ethanol extract; The purity of said octacosanol is 10%-90%.Both all can buy through commercially available.
Nourishing tonic for sport of the present invention can add suitable adjuvant, is prepared into various dosage forms, like tablet, pill, granule or capsule etc.
For example, can adopt following method that nourishing tonic for sport of the present invention is prepared into tablet: promptly, to add the appropriate amount of starch mixing by weight the pure and mild Radix Et Caulis Acanthopanacis Senticosi extract of octacosane is fully mixed; Adding an amount of 10% starch slurry fully refines and closes; Cross 20 mesh sieves and granulate, after the drying, cross 20 mesh sieve granulate; Add an amount of magnesium stearate mixing, compacting in flakes.
Weight portion described in the present invention can be the known content units of field of nutrition such as microgram, milligram, gram, kilogram.
Nourishing tonic for sport provided by the present invention can promote glycogen synthetic better, and stamina intensifying recovers physical ability.
The specific embodiment
Following examples are used to explain the present invention, but are not used for limiting scope of the present invention.
Embodiment 1
With the abundant mixing of octacosanol powder 10g of Radix Et Caulis Acanthopanacis Senticosi ethanol extract 250g and 90%, add 80 gram starch mixings, adding 20 grams 10% starch slurry fully refines and closes; Cross 20 mesh sieves and granulate, after the drying, cross 20 mesh sieve granulate; Add 0.5 gram magnesium stearate mixing, compacting promptly gets 1000 in tablet in flakes.Wherein, the Radix Et Caulis Acanthopanacis Senticosi ethanol extract is available from Baoji, Shaanxi province city Yongjia natural plants development corporation, Ltd., and octacosanol is available from the gloomy not biotechnology in Shaanxi Co., Ltd.
Embodiment 2
With the abundant mixing of octacosanol powder 10g of Radix Et Caulis Acanthopanacis Senticosi ethanol extract 200g and 90%, add 130 gram starch mixings, adding 20 grams 10% starch slurry fully refines and closes; Cross 20 mesh sieves and granulate, after the drying, cross 20 mesh sieve granulate; Add 0.5 gram magnesium stearate mixing, compacting promptly gets 1000 in tablet in flakes.Wherein, the Radix Et Caulis Acanthopanacis Senticosi ethanol extract is available from Baoji, Shaanxi province city Yongjia natural plants development corporation, Ltd., and octacosanol is available from the gloomy not biotechnology in Shaanxi Co., Ltd.
Embodiment 3
With the abundant mixing of octacosanol powder 10g of Radix Et Caulis Acanthopanacis Senticosi ethanol extract 150g and 90%, add 220 gram starch mixings, adding 20 grams 10% starch slurry fully refines and closes; Cross 20 mesh sieves and granulate, after the drying, cross 20 mesh sieve granulate; Add 0.5 gram magnesium stearate mixing, compacting promptly gets 1000 in tablet in flakes.Wherein, the Radix Et Caulis Acanthopanacis Senticosi ethanol extract is available from Baoji, Shaanxi province city Yongjia natural plants development corporation, Ltd., and octacosanol is available from the gloomy not biotechnology in Shaanxi Co., Ltd.
Embodiment 4
With the abundant mixing of octacosanol powder 10g of Radix Et Caulis Acanthopanacis Senticosi ethanol extract 90g and 10%, add 280 gram starch mixings, adding 20 grams 10% starch slurry fully refines and closes; Cross 20 mesh sieves and granulate, after the drying, cross 20 mesh sieve granulate; Add 0.5 gram magnesium stearate mixing, compacting promptly gets 1000 in tablet in flakes.
Embodiment 5
With the abundant mixing of octacosanol powder 10g of Radix Et Caulis Acanthopanacis Senticosi ethanol extract 500g and 90%, add 230 gram starch mixings, adding 20 grams 10% starch slurry fully refines and closes; Cross 20 mesh sieves and granulate, after the drying, cross 20 mesh sieve granulate; Add 0.5 gram magnesium stearate mixing, compacting promptly gets 2000 in tablet in flakes.
Embodiment 6
With the abundant mixing of octacosanol powder 10g of Radix Et Caulis Acanthopanacis Senticosi ethanol extract 100g and 50%, add 280 gram starch mixings, adding 20 grams 10% starch slurry fully refines and closes; Cross 20 mesh sieves and granulate, after the drying, cross 20 mesh sieve granulate; Add 0.5 gram magnesium stearate mixing, compacting promptly gets 1000 in tablet in flakes.
Embodiment 7
With the abundant mixing of octacosanol powder 10g of Radix Et Caulis Acanthopanacis Senticosi ethanol extract 50g and 50%, add 280 gram starch mixings, adding 20 grams 10% starch slurry fully refines and closes; Cross 20 mesh sieves and granulate, after the drying, cross 20 mesh sieve granulate; Add 0.5 gram magnesium stearate mixing, compacting promptly gets 1000 in tablet in flakes.
Embodiment 8
With the abundant mixing of octacosanol powder 10g of Radix Et Caulis Acanthopanacis Senticosi ethanol extract 10g and 10%, add 80 gram starch mixings, adding 20 grams 10% starch slurry fully refines and closes; Cross 20 mesh sieves and granulate, after the drying, cross 20 mesh sieve granulate; Add 0.5 gram magnesium stearate mixing, compacting promptly gets 300 in tablet in flakes.
Embodiment 9
Get the octacosanol powder 30g of Radix Et Caulis Acanthopanacis Senticosi ethanol extract 150g, purity 90%, cross 40 mesh sieves successively, stir; Pour capsule into and fill in the mould, process capsule, the powder of polishing capsule surface; With container packing such as medicine bottles, add desiccant, Cotton Gossypii in the container, seal electromagnetic induction film afterwards; Spiral cover, sterilization.
Embodiment 10
Get octacosanol powder 30g, starch 200 grams of Radix Et Caulis Acanthopanacis Senticosi ethanol extract 150g, purity 90%, cross 40 mesh sieves successively, stir; The HPMC that adds above-mentioned material gross weight 2.5% again; All materials are added groove mix in the machine, the adding appropriate amount of purified water is closed and is sticked together, and processes soft material; Soft material is put into pill behind the pellet processing machine, oven dry, polishing is carried out packing behind the whole ball, makes pill.
Embodiment 11
Get octacosanol powder 30g, the starch 200g of Radix Et Caulis Acanthopanacis Senticosi ethanol extract 150g, purity 90%, cross 40 mesh sieves successively, stir; The ethanol 100g of use 80% is as adhesive; Make soft material, above soft material is waved the granulator granulation through the YK-160 type of 12 mesh sieves, process wet granular; The wet granular component is divided, treat ethanol volatilization fully after, above material is inserted in the multi-functional granulator of DPL-30 type, 50 ℃ of airpillow-dry one hour, make the final products moisture Control in 5%; Carry out granulate and packing again.
Experimental example 1 nourishing tonic for sport of the present invention is to the observation on effect of application evaluation of movement human
1. experimental subject:
Select 48 of 5 monthly age SD rats for use, be divided into 4 groups at random: blank control group (A), Radix Et Caulis Acanthopanacis Senticosi group (B), octacosanol group (C) and Radix Et Caulis Acanthopanacis Senticosi+octacosanol group (D).
2. experimental technique:
Blank control group is used distilled water; The Radix Et Caulis Acanthopanacis Senticosi group is with the tablet (0.4 is dissolved in the 30ml distilled water) of Comparative Examples 1; The octacosanol group is with the tablet (0.4 is dissolved in the 30ml distilled water) of Comparative Examples 2, and Radix Et Caulis Acanthopanacis Senticosi+octacosanol group is with the tablet (0.4 is dissolved in the 30ml distilled water) of embodiment 6.
The tablet of Comparative Examples 1: get Radix Et Caulis Acanthopanacis Senticosi extract 100g, add 320 gram starch mixings, adding 20 grams 10% starch slurry fully refines and closes, and crosses 20 mesh sieves and granulates, and after the drying, crosses 20 mesh sieve granulate, adds 0.5 and restrains the magnesium stearate mixing, and compacting promptly gets 1000 in tablet in flakes.
The tablet of Comparative Examples 2: get octacosanol powder 20g, add 230 gram starch mixings, adding 20 grams 10% starch slurry fully refines and closes, and crosses 20 mesh sieves and granulates, and after the drying, crosses 20 mesh sieve granulate, adds 0.5 and restrains the magnesium stearate mixing, and compacting promptly gets 1000 in tablet in flakes.
Each is organized rat and regularly irritates stomach (adopting the equal-volume administration by gavage) every day three times, each 10ml, continuous 15 days equal every day.Select the influence experiment of swimming with a load attached to the body experiment in the national regulation index, hepatic glycogen to measure.
Swimming with a load attached to the body experiment: with every group of rat average 30 ± 1 ℃ in water temperature; Depth of water 50cm; In the ceramic cylinder of diameter 50cm with fine rule rope fixedly the heavy lead of 5g carry out swimming with a load attached to the body and train to power and exhaust, power exhaust criterion for the rat submerged above 10s, can't emerge; The power of being regarded as exhausts, and record power exhausts the time.
The influence experiment of hepatic glycogen: mice is got liver through taking off after cervical vertebra is put to death immediately, behind the normal saline flushing, blots with filter paper, according to the explanation of test kit, carries out the liver glycogen Determination on content.Concrete grammar is: accurately take by weighing 100mg, put into the trichloroacetic acid (TCA) of 8ml 5%, homogenate is with the centrifugal 15min of 3000r/min; Get in the ethanol that the 1ml supernatant joins 4ml 95% fully that mixing to interface disappears, behind the deposition 12h, the centrifugal supernatant of abandoning is transferred to the 10ml color comparison tube after dissolving with the 2ml redistilled water; In standard pipe, add 1mg/ml glucose titer 0.5ml and 1.5ml redistilled water simultaneously, add the 2ml redistilled water in the blank pipe, each pipe is placed ice-water bath, add the 10ml anthrone reagent; Mixing, be cooled to room temperature after, place boiling water bath to boil 15min each pipe; Move to ice-water bath immediately, be cooled to room temperature, mixing; Under the 620nm wavelength, with blank pipe zeroing, colorimetric determination absorbance.
3. result
3.1 rat swimming with a load attached to the body test
The rat swimming with a load attached to the body time: blank control group (A) is that 125.20 ± 53.58min, Radix Et Caulis Acanthopanacis Senticosi group (B) are that 149.73 ± 62.57min, octacosanol group (C) are that 137.79 ± 79.08min, Radix Et Caulis Acanthopanacis Senticosi+octacosanol group (D) are 211.34 ± 47.52min.
Experimental result shows that the swimming time of B group and D group is all than the obvious prolongation of blank control group (P＜0.05), and the C group does not have significant difference with matched group.The length of swimming time has reflected the tired degree of animal movement.
3.2 the influence of rats'liver glycogen
Glycogen is the main energy sources material of long-time strenuous exercise, and the deposit of hepatic glycogen has important and positive effect to the motion body.The mensuration result of hepatic glycogen is as shown in table 1.
Table 1 rat serum lactic acid and hepatic glycogen are measured the result
| Divide into groups | The example number | Hepatic glycogen (mg/kg) |
| A | 12 | 12.35±3.95 |
| B | 12 | 35.54±6.69 * |
| C | 12 | 28.14±4.83 * |
| D | 12 | 57.76±8.94 **# + |
Annotate: compare with the A group:
*P＜0.05,
*P＜0.01, compare with the B group: #P＜0.05, compare with the C group :+P＜0.05
Visible by table 1; The hepatic glycogen level of Radix Et Caulis Acanthopanacis Senticosi group (B), octacosanol group (C) and Radix Et Caulis Acanthopanacis Senticosi+octacosanol group (D) group is all apparently higher than blank control group (A); And the hepatic glycogen level of D group is apparently higher than B, C group; The deposit of pointing out this product can increase hepatic glycogen, thus the physical ability of enhancement, physical strength reinforcing, antifatigue effect had.
4. conclusion:
Nourishing tonic for sport of the present invention can prolong movement time, and can promote glycogen synthetic better, promotes physical ability.
Claims (6)
1. a nourishing tonic for sport is characterized in that, contains the component of following weight portion:
Radix Et Caulis Acanthopanacis Senticosi extract 1～50
Octacosanol 1;
Said Radix Et Caulis Acanthopanacis Senticosi extract is the Radix Et Caulis Acanthopanacis Senticosi ethanol extract.
2. nourishing tonic for sport as claimed in claim 1 is characterized in that, contains the component of following weight portion:
Radix Et Caulis Acanthopanacis Senticosi extract 1～20
Octacosanol 1;
Said Radix Et Caulis Acanthopanacis Senticosi extract is the Radix Et Caulis Acanthopanacis Senticosi ethanol extract.
3. nourishing tonic for sport as claimed in claim 2 is characterized in that, contains the component of following weight portion:
Radix Et Caulis Acanthopanacis Senticosi extract 2～10
Octacosanol 1;
Said Radix Et Caulis Acanthopanacis Senticosi extract is the Radix Et Caulis Acanthopanacis Senticosi ethanol extract.
4. nourishing tonic for sport as claimed in claim 3 is characterized in that, contains the component of following weight portion:
Radix Et Caulis Acanthopanacis Senticosi extract 5
Octacosanol 1;
Said Radix Et Caulis Acanthopanacis Senticosi extract is the Radix Et Caulis Acanthopanacis Senticosi ethanol extract.
5. like the arbitrary described nourishing tonic for sport of claim 1-4, it is characterized in that the purity of said octacosanol is 10%-90%.
6. like the arbitrary described nourishing tonic for sport of claim 1-4, it is characterized in that this nourishing tonic for sport is tablet, granule, pill or capsule.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2008102403961A CN101439064B (en) | 2008-12-19 | 2008-12-19 | Nourishing tonic for sport |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2008102403961A CN101439064B (en) | 2008-12-19 | 2008-12-19 | Nourishing tonic for sport |
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| Publication Number | Publication Date |
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| CN101439064A CN101439064A (en) | 2009-05-27 |
| CN101439064B true CN101439064B (en) | 2012-03-14 |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103907919A (en) * | 2013-01-04 | 2014-07-09 | 杨立英 | Composition capable of reducing athletic fatigue and rapidly replenishing physical fitness |
| CN106805223A (en) * | 2015-12-01 | 2017-06-09 | 杭州衡美食品科技有限公司 | A kind of sports type nutrition bar |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1736220A (en) * | 2005-08-04 | 2006-02-22 | 苟春虎 | Anti-fatigue yoghurt tablet |
| US20070207187A1 (en) * | 2004-09-29 | 2007-09-06 | Mizuo Yajima | Functional Composition Or Food Comprising Whey Protein, Antibody Derived From Milk Or Antibody |
| CN101248873A (en) * | 2008-04-03 | 2008-08-27 | 四川健丰科技发展有限公司 | Drinking food product with sight protection function |
-
2008
- 2008-12-19 CN CN2008102403961A patent/CN101439064B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070207187A1 (en) * | 2004-09-29 | 2007-09-06 | Mizuo Yajima | Functional Composition Or Food Comprising Whey Protein, Antibody Derived From Milk Or Antibody |
| CN1736220A (en) * | 2005-08-04 | 2006-02-22 | 苟春虎 | Anti-fatigue yoghurt tablet |
| CN101248873A (en) * | 2008-04-03 | 2008-08-27 | 四川健丰科技发展有限公司 | Drinking food product with sight protection function |
Non-Patent Citations (3)
| Title |
|---|
| 张东杰，等.刺五加茶饮料抗疲劳作用的实验研究.《营养学报》.2003,第25卷(第3期),第309-311页. * |
| 曹志然,等.二十八烷醇对实验动物免疫功能及游泳耐力的影响.《食品科学》.2004,第25卷(第7期),第158-160页. * |
| 陈芳，等.二十八烷醇提取物的抗疲劳作用研究.《营养学报》.2006,第28卷(第3期),第269-270页. * |
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